CN110772449A

CN110772449A - Skin rejuvenation freeze-dried powder and preparation method thereof

Info

Publication number: CN110772449A
Application number: CN201911260468.3A
Authority: CN
Inventors: 王洪波
Original assignee: Individual
Current assignee: Individual
Priority date: 2019-12-10
Filing date: 2019-12-10
Publication date: 2020-02-11

Abstract

The invention discloses a freeze-dried powder for repairing and tendering skin, which comprises the following components in percentage by mass: 4-5% of mannitol, 2.5-3.5% of trehalose, 32.5-3.5% of oligopeptide, 40.5-1.5% of palmitoyl pentapeptide, 0.03-0.07% of adenosine, 0.03-0.07% of copper chlorophyll, 0.5-1.5% of hydrolyzed collagen, 1.5-2.5% of sodium hyaluronate and 84.5-86% of water, wherein the preparation method comprises the following steps: s1 and S1, weighing sodium hyaluronate, hydrolyzed collagen, mannitol and water, stirring for 12-30 minutes, and heating to obtain a transparent first preparation solution; s2, cooling the transparent first preparation liquid; s3, weighing trehalose, oligopeptide-3, palmitoyl pentapeptide-4, adenosine and copper chlorophyll, adding into the first transparent solution, and stirring and heating to obtain a second transparent solution; and S4, filling the transparent preparation liquid II into a penicillin bottle, covering a bottle stopper, putting the penicillin bottle into freeze-drying equipment, and freeze-drying. The invention has the advantages that: can effectively repair damaged skin, keep skin moisture, and increase skin elasticity and luster.

Description

Skin rejuvenation freeze-dried powder and preparation method thereof

Technical Field

The invention relates to the technical field of cosmetics, in particular to a freeze-dried powder for repairing and tendering skin and a preparation method thereof.

Background

Nowadays, social substance life is more and more abundant, people pay more and more attention to the personal appearance problem, however, with the increase of age and the deterioration of living environment, the metabolism of skin is reduced, the function of absorbing various beneficial elements is reduced, water is easy to lose, and various harmful substances are easy to stay on the surface of the skin, so that the skin care product gradually loses the original elasticity, and the skin care product becomes the most popular choice of most people, especially contemporary women, and the good skin care product can play the effects of promoting skin blood circulation, repairing skin injury, keeping skin moisture, increasing skin elasticity and luster, maintaining sensitive skin and the like.

However, although skin care products on the market are full of scales and various, most skin care products are fine chemical products, only the surface layer problem of the skin is solved, the skin repair effect cannot be fundamentally achieved, and some cosmetics are added with components such as hormone, so that the beauty effect is not obvious, the negative influence is caused on the human body, and the use safety performance is poor.

Disclosure of Invention

The technical problem to be solved by the invention is to provide a freeze-dried powder for repairing and tendering skin and a preparation method thereof, wherein the freeze-dried powder can effectively repair damaged skin, keep skin moisture and increase skin elasticity and luster.

In order to solve the technical problems, the technical scheme provided by the invention is as follows: the freeze-dried powder for repairing and tendering skin comprises the following components in percentage by mass: 4-5% of mannitol, 2.5-3.5% of trehalose, 32.5-3.5% of oligopeptide, 40.5-1.5% of palmitoyl pentapeptide, 0.03-0.07% of adenosine, 0.03-0.07% of copper chlorophyll, 0.5-1.5% of hydrolyzed collagen, 1.5-2.5% of sodium hyaluronate and 84.5-86% of water.

Preferably, the composition comprises the following components in percentage by mass: 4.2-4.8% of mannitol, 2.7-3.2% of trehalose, 32.7-3.2% of oligopeptide, 40.7-1.3% of palmitoyl pentapeptide, 0.04-0.06% of adenosine, 0.04-0.06% of copper chlorophyll, 0.7-1.3% of hydrolyzed collagen, 1.7-2.3% of sodium hyaluronate and 84.5-85.5% of water.

Preferably, the composition comprises the following components in percentage by mass: 5% of mannitol, 3% of trehalose, 33% of oligopeptide, 41% of palmitoyl pentapeptide, 0.05% of adenosine, 0.05% of copper chlorophyll, 1% of hydrolyzed collagen, 2% of sodium hyaluronate and 84.9% of water.

Preferably, the water is purified water after secondary filtration.

Preferably, the preparation method of the freeze-dried powder for repairing and tendering skin comprises the following steps:

s1, weighing sodium hyaluronate, hydrolyzed collagen, mannitol and water, stirring for 12-30 minutes, and heating at 70-80 ℃ to obtain a first transparent solution;

s2, cooling the transparent first preparation solution to enable the transparent first preparation solution to be cooled to 15-30 ℃ at a constant speed;

s3, weighing trehalose, oligopeptide-3, palmitoyl pentapeptide-4, adenosine and copper chlorophyll, adding into the first transparent solution, stirring for 15-30 minutes, heating at 40-60 ℃ to obtain a second transparent solution;

s4, filling the transparent preparation liquid II into a penicillin bottle, covering a bottle stopper, putting the penicillin bottle into a freeze-drying device, and freeze-drying at the temperature of-15 to-5 ℃.

Compared with the prior art, the invention has the advantages that: according to the skin rejuvenation freeze-dried powder and the preparation method thereof, trehalose can form a unique protective film on the surface of cells under severe environmental conditions such as high temperature, high cold, high osmotic pressure, drying and dehydration, so that protein molecules can be effectively protected from inactivation without denaturation, and skin cells can be well protected; oligopeptide-3 is combined with a cell surface specific receptor to regulate and control division, reproduction and growth differentiation of skin epithelium, endothelium and stromal cells, promote cell metabolism, enhance oxidation and have good skin repair effect; palmitoyl pentapeptide-4 can penetrate dermis to increase collagen, reverse skin aging process through reconstruction from inside to outside, stimulate collagen, elastic fiber and hyaluronic acid proliferation, improve skin water content and water locking degree, increase skin thickness and reduce fine lines, and enhance skin absorption capacity; meanwhile, the freeze-drying synthesis process is adopted to fully extract the effective components in the raw materials, so that the freeze-drying powder is smeared on the face when in use, and the face mask is convenient to use and good in absorptivity.

Detailed Description

Example one

The freeze-dried powder for repairing and tendering skin comprises the following components in percentage by mass: 4.8% of mannitol, 3.2% of trehalose, 32.8% of oligopeptide, 41.2% of palmitoyl pentapeptide, 0.04% of adenosine, 0.06% of copper chlorophyll, 0.8% of hydrolyzed collagen, 2.2% of sodium hyaluronate and 84.9% of water.

The preparation method comprises the following steps:

s1, weighing sodium hyaluronate, hydrolyzed collagen, mannitol and water, stirring for 15 minutes, and heating at the temperature of 70 ℃ to obtain a transparent first preparation solution;

s2, cooling the transparent first preparation solution to enable the temperature to be reduced to 20 ℃ at a constant speed;

s3, weighing trehalose, oligopeptide-3, palmitoyl pentapeptide-4, adenosine and copper chlorophyll, adding into the first transparent solution, stirring for 20 minutes, heating to 45 ℃ to obtain a second transparent solution;

s4, filling the transparent preparation liquid II into a penicillin bottle, covering a bottle stopper, putting the penicillin bottle into freeze-drying equipment, and freeze-drying at the temperature of-8 ℃.

Example two

The freeze-dried powder for repairing and tendering skin comprises the following components in percentage by mass: 5% of mannitol, 3% of trehalose, 33% of oligopeptide, 41% of palmitoyl pentapeptide, 0.05% of adenosine, 0.05% of copper chlorophyll, 1% of hydrolyzed collagen, 2% of sodium hyaluronate and 84.9% of water.

The preparation method comprises the following steps:

s1, weighing sodium hyaluronate, hydrolyzed collagen, mannitol and water, stirring for 25 minutes, and heating at 75 ℃ to obtain a first transparent solution;

s2, cooling the transparent first preparation solution to enable the temperature to be reduced to 25 ℃ at a constant speed;

s3, weighing trehalose, oligopeptide-3, palmitoyl pentapeptide-4, adenosine and copper chlorophyll, adding into the first transparent solution, stirring for 25 minutes, heating to 50 ℃ to obtain a second transparent solution;

s4, filling the transparent preparation liquid II into a penicillin bottle, covering a bottle stopper, putting the penicillin bottle into freeze-drying equipment, and freeze-drying at the temperature of-10 ℃.

The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.

Claims

1. The freeze-dried powder for repairing and tendering skin is characterized by comprising the following components in percentage by mass: 4-5% of mannitol, 2.5-3.5% of trehalose, 32.5-3.5% of oligopeptide, 40.5-1.5% of palmitoyl pentapeptide, 0.03-0.07% of adenosine, 0.03-0.07% of copper chlorophyll, 0.5-1.5% of hydrolyzed collagen, 1.5-2.5% of sodium hyaluronate and 84.5-86% of water.

2. The freeze-dried powder for repairing skin tenderness as claimed in claim 1, which is characterized by comprising the following components in percentage by mass: 4.2-4.8% of mannitol, 2.7-3.2% of trehalose, 32.7-3.2% of oligopeptide, 40.7-1.3% of palmitoyl pentapeptide, 0.04-0.06% of adenosine, 0.04-0.06% of copper chlorophyll, 0.7-1.3% of hydrolyzed collagen, 1.7-2.3% of sodium hyaluronate and 84.5-85.5% of water.

3. The freeze-dried powder for repairing skin tenderness as claimed in claim 1, which is characterized by comprising the following components in percentage by mass: 5% of mannitol, 3% of trehalose, 33% of oligopeptide, 41% of palmitoyl pentapeptide, 0.05% of adenosine, 0.05% of copper chlorophyll, 1% of hydrolyzed collagen, 2% of sodium hyaluronate and 84.9% of water.

4. The lyophilized powder for repairing skin rejuvenation as claimed in claim 1, which is characterized in that: the water is purified water after secondary filtration.

5. The preparation method of the freeze-dried powder for repairing tender skin as claimed in claim 1, which is characterized by comprising the following steps: