CN110770343A - 用于rna干扰的长双链rna - Google Patents

用于rna干扰的长双链rna Download PDF

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CN110770343A
CN110770343A CN201880024222.3A CN201880024222A CN110770343A CN 110770343 A CN110770343 A CN 110770343A CN 201880024222 A CN201880024222 A CN 201880024222A CN 110770343 A CN110770343 A CN 110770343A
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ldrna
mrna
cells
composition
complementary
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Chinese (zh)
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李东起
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Olix Pharmaceuticals Inc
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Chengjunguan University School-Industry-University Cooperation Group
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CN201880024222.3A 2017-02-10 2018-02-12 用于rna干扰的长双链rna Pending CN110770343A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762457282P 2017-02-10 2017-02-10
US62/457,282 2017-02-10
PCT/IB2018/000330 WO2018146557A2 (en) 2017-02-10 2018-02-12 Long double-stranded rna for rna interference

Publications (1)

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CN110770343A true CN110770343A (zh) 2020-02-07

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CN201880024222.3A Pending CN110770343A (zh) 2017-02-10 2018-02-12 用于rna干扰的长双链rna

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US (1) US11591600B2 (https=)
EP (1) EP3580339A4 (https=)
JP (1) JP7424728B2 (https=)
KR (1) KR20190108167A (https=)
CN (1) CN110770343A (https=)
WO (1) WO2018146557A2 (https=)

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DK2631291T3 (da) 2010-10-22 2019-06-11 Olix Pharmaceuticals Inc Nukleinsyremolekyler, der inducerer rna-interferens, og anvendelser deraf
KR101567576B1 (ko) 2012-05-22 2015-11-10 올릭스 주식회사 세포 내 관통능을 가지고 ｒｎａ 간섭을 유도하는 핵산 분자 및 그 용도
JP7027311B2 (ja) 2015-11-16 2022-03-01 オリックス ファーマシューティカルズ，インコーポレーテッド ＭｙＤ８８又はＴＬＲ３を標的とするＲＮＡ複合体を使用した加齢黄斑変性の治療
JP6944942B2 (ja) 2016-02-02 2021-10-06 オリックス ファーマシューティカルズ，インコーポレーテッド ＩＬ４Ｒα、ＴＲＰＡ１、またはＦ２ＲＬ１を標的とするＲＮＡ複合体を用いたアトピー性皮膚炎および喘息の治療
CN108779464B (zh) 2016-02-02 2022-05-17 奥利克斯医药有限公司 使用靶向angpt2和pdgfb的rna复合物治疗血管生成相关性疾病
JP7049262B2 (ja) 2016-04-11 2022-04-06 オリックス ファーマシューティカルズ，インコーポレーテッド 結合組織成長因子を標的とするｒｎａ複合体を用いた特発性肺胞線維症の治療
KR101916652B1 (ko) 2016-06-29 2018-11-08 올릭스 주식회사 작은 간섭 rna의 rna 간섭효과 증진용 화합물 및 이의 용도
EP3580339A4 (en) 2017-02-10 2020-12-23 Research & Business Foundation Sungkyunkwan University LONG DOUBLE STRAND RNA FOR RNA INTERFERENCE
WO2023043239A1 (ko) * 2021-09-15 2023-03-23 올릭스 주식회사 선천성 면역 반응 유도 효과를 갖는 이중가닥 rna 및 이의 용도
WO2024186166A1 (ko) * 2023-03-08 2024-09-12 올릭스 주식회사 선천성 면역 반응 유도 효과를 갖는 이중가닥 rna 및 이의 용도
WO2026054553A1 (ko) * 2024-09-06 2026-03-12 올릭스 주식회사 선천성 면역 반응 기반 항암 요법을 위한 이중 가닥 rna 및 이의 용도

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