CN110742936A - Traditional Chinese medicine for treating gastrorrhagia and preparation method thereof - Google Patents

Traditional Chinese medicine for treating gastrorrhagia and preparation method thereof Download PDF

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CN110742936A
CN110742936A CN201911011939.7A CN201911011939A CN110742936A CN 110742936 A CN110742936 A CN 110742936A CN 201911011939 A CN201911011939 A CN 201911011939A CN 110742936 A CN110742936 A CN 110742936A
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chinese medicine
gastrorrhagia
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刘桂安
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

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Abstract

The invention discloses a traditional Chinese medicine for treating gastrorrhagia and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine for treating gastrorrhagia is prepared from the following raw materials in parts by weight: 18-22g of rhodomyrtus tomentosa root, 18-22g of red peony, 18-22g of copperleaf herb, 18-22g of herba Melastomatis Cannabis, 18-22g of white backleaf, 18-22g of rhizoma polygoni paleacei, 18-22g of uncinata spikemoss herb and 18-22g of toddalia asiatica. The invention also discloses a preparation method of the traditional Chinese medicine for treating gastrorrhagia. The traditional Chinese medicine for treating gastrorrhagia is prepared from multiple traditional Chinese medicines, has reasonable composition and proper compatibility, fully releases the active ingredients of each component, has the effects of removing blood stasis, stopping bleeding, promoting blood circulation and relieving pain, and is mainly used for treating gastrorrhagia, hemoptysis, hematochezia, hemorrhoidal bleeding and other diseases.

Description

Traditional Chinese medicine for treating gastrorrhagia and preparation method thereof
Technical Field
The invention relates to a traditional Chinese medicine for treating gastrorrhagia and a preparation method thereof, and belongs to the technical field of medicinal liquor.
Background
Gastrorrhagia refers to upper gastrointestinal hemorrhage, which refers to hemorrhage caused by pathological changes of the digestive tract above the ligamentum flexor, including esophagus, stomach, duodenum or pancreas and gallbladder. The clinical manifestations of the disease are hematemesis or dark stool, and the bleeding part can be determined by gastroscopy. When the amount of the bleeding is large, the bleeding is often accompanied by acute peripheral circulation failure caused by hypovolemia, the bleeding is common emergency, and if the bleeding is not treated properly, the bleeding can also endanger life and even cause death.
At present, most western medicines for treating gastrorrhagia adopt medicines with the effects of reducing the acidity in stomach to prevent the hydrogen ions from being dispersed reversely to aggravate gastric mucosa damage and stopping bleeding, and are supplemented with blood transfusion and fluid infusion, so that the treatment time is short, but the treatment effect is poor, the recurrence is easy, and the side effect is large. The Chinese patent medicine has the defects of complex prescription, unobvious effect, long administration time and the like although the Chinese patent medicine has small toxic and side effects.
In view of this, there is an urgent need for a new traditional Chinese medicine for treating gastrorrhagia and a preparation method thereof, so as to solve the defects of the prior art.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine for treating gastrorrhagia. The traditional Chinese medicine for treating gastrorrhagia is prepared from multiple traditional Chinese medicines, has reasonable composition and proper compatibility, fully releases the active ingredients of each component, has the effects of removing blood stasis, stopping bleeding, promoting blood circulation and relieving pain, and is mainly used for treating gastrorrhagia, hemoptysis, hematochezia, hemorrhoidal bleeding and other diseases.
The technical scheme for solving the technical problems is as follows: a traditional Chinese medicine for treating gastrorrhagia is prepared from the following raw materials by weight: 18-22g of rhodomyrtus tomentosa root, 18-22g of red peony, 18-22g of copperleaf herb, 18-22g of herba Melastomatis Cannabis, 18-22g of white backleaf, 18-22g of rhizoma polygoni paleacei, 18-22g of uncinata spikemoss herb and 18-22g of toddalia asiatica.
The rhodomyrtus tomentosa root selected by the invention is slightly bitter and astringent in taste, has mild nature, enters spleen and liver channels, and has the effects of promoting digestion, relieving diarrhea, reducing swelling and stopping bleeding; the red peony is slightly astringent in taste and warm in nature, and has the effects of tonifying qi, generating blood, dissipating blood stasis and stopping bleeding; the copperleaf herb is bitter and astringent in taste, cold in nature, and has the effects of clearing heat and removing toxicity, promoting diuresis, astringing and stopping bleeding, and the lung channel is accessed; the whole plant of Melastoma dodecandrum lour and the like is used for medicine, and has the effects of astringing intestine to stop diarrhea, relaxing muscles and tendons to promote blood circulation, enriching blood and preventing miscarriage, and clearing heat and drying dampness; the white dorsum leaves are slightly bitter and astringent in taste, have neutral nature, enter liver and spleen channels, and have the effects of softening liver, activating blood circulation, invigorating spleen, eliminating dampness, astringing and relieving depletion; the rhizoma polygoni paleacei is bitter and astringent in taste and slightly warm in nature, enters spleen, stomach and kidney channels, and has the effects of activating blood circulation, dissipating blood stasis, relieving pain and stopping bleeding; selaginella uncinata, sweet and light in flavor, cool in nature, and entering lung, liver and large intestine channels, has the effects of clearing heat and promoting diuresis, stopping bleeding and relieving cough; toddalia asiatica, bitter in taste, numb in nature and warm in nature, has the effects of promoting blood circulation, removing blood stasis, dispelling wind, removing dampness, and relieving swelling and pain. The raw materials play a single role, simultaneously play the efficacies of promoting blood circulation by removing blood stasis, relieving swelling and pain, stopping bleeding and reuniting bones, and are mainly used for treating diseases such as traumatic injury, lumbocrural pain, fracture and the like.
The invention has the beneficial effects that:
(1) the traditional Chinese medicine for treating gastrorrhagia is prepared from multiple traditional Chinese medicines, has reasonable composition and proper compatibility, fully releases the active ingredients of each component, has the effects of removing blood stasis, stopping bleeding, promoting blood circulation and relieving pain, and is mainly used for treating gastrorrhagia, hemoptysis, hematochezia, hemorrhoidal bleeding and other diseases.
(2) The invention does not contain chemical additives such as antibacterial agents, preservatives and the like, has no toxic or side effect, quick and lasting effect, high cure rate and low cost.
On the basis of the technical scheme, the invention can be further improved as follows.
Further, the feed is prepared from the following raw materials in parts by weight: 18g of rhodomyrtus tomentosa root, 22g of red peony, 18g of copperleaf herb, 22g of herba whiskeris, 18g of folium Malloti Apeltae, 22g of rhizoma polygoni palustris, 18g of uncinata spikemoss herb and 22g of toddalia asiatica.
The adoption of the further beneficial effects is as follows: the traditional Chinese medicine for treating gastrorrhagia, which is prepared from the raw materials according to the proportion, has more obvious drug effect.
Further, the feed is prepared from the following raw materials in parts by weight: 20g of rhodomyrtus tomentosa root, 20g of red peony, 20g of copperleaf herb, 20g of herba whiskeris, 20g of white back leaf, 20g of rhizoma polygoni paleacei, 20g of uncinata spikemoss herb and 20g of toddalia asiatica.
The adoption of the further beneficial effects is as follows: the traditional Chinese medicine for treating gastrorrhagia, which is prepared from the raw materials according to the proportion, has more obvious drug effect.
Further, the feed is prepared from the following raw materials in parts by weight: 22g of rhodomyrtus tomentosa roots, 18g of red peony, 22g of copperleaf herb, 18g of herba whistles, 22g of gynura divaricata, 18g of rhizoma polygoni palustris, 22g of uncinata spikemoss herb and 18g of toddalia asiatica.
The adoption of the further beneficial effects is as follows: the traditional Chinese medicine for treating gastrorrhagia, which is prepared from the raw materials according to the proportion, has more obvious drug effect.
The second purpose of the invention is to provide a preparation method of the traditional Chinese medicine for treating gastrorrhagia. The traditional Chinese medicine for treating gastrorrhagia has the advantages of simple preparation method, easy operation, wide medicine sources, low cost and wide market prospect, and is suitable for popularization and application.
The technical scheme for solving the technical problems is as follows: a preparation method of a traditional Chinese medicine for treating gastrorrhagia comprises the following steps: preparing the following raw materials by weight: 18-22g of rhodomyrtus tomentosa root, 18-22g of red peony, 18-22g of copperleaf herb, 18-22g of herba Melastomatis Cannabis, 18-22g of folium Malloti Apeltae, 18-22g of rhizoma polygoni palustris, 18-22g of uncinata spikemoss herb and 18-22g of toddalia asiatica are respectively crushed and uniformly mixed to obtain the traditional Chinese medicine for treating gastrorrhagia.
The invention has the beneficial effects that:
the traditional Chinese medicine for treating gastrorrhagia has the advantages of simple preparation method, easy operation, wide medicine sources, low cost and wide market prospect, and is suitable for popularization and application.
The drinking method of the traditional Chinese medicine for treating gastrorrhagia comprises the following steps:
weighing the traditional Chinese medicine raw materials according to the proportion, taking 1 dose of decoction 2-3 times per day, 1 dose per day, 1 course of 6 days, 1-3 courses of medicine taking, and avoiding spicy food during medicine taking.
On the basis of the technical scheme, the invention can be further improved as follows.
Further, the particle size of the crushed particles is 1cm-2 cm.
The adoption of the further beneficial effects is as follows: the particle size of the crushed Chinese medicinal composition is 1cm-2cm, so that the beneficial components of the raw materials in the Chinese medicinal composition for treating gastrorrhagia are easier to dissolve, and the medicinal effect is better.
Detailed Description
The principles and features of this invention are described below in conjunction with specific embodiments, which are set forth merely to illustrate the invention and are not intended to limit the scope of the invention.
Example 1:
the traditional Chinese medicine for treating gastrorrhagia is prepared from the following raw materials in parts by weight: 18g of rhodomyrtus tomentosa root, 22g of red peony, 18g of copperleaf herb, 22g of herba whiskeris, 18g of folium Malloti Apeltae, 22g of rhizoma polygoni palustris, 18g of uncinata spikemoss herb and 22g of toddalia asiatica.
The preparation method of the traditional Chinese medicine for treating gastrorrhagia comprises the following steps: preparing the following raw materials by weight: 18g of rhodomyrtus tomentosa root, 22g of red peony, 18g of copperleaf herb, 22g of herba whiskeris, 18g of folium Malloti Apeltae, 22g of rhizoma polygoni palustris, 18g of uncinata spikemoss herb and 22g of toddalia asiatica are respectively ground to the particle size of 1cm-2cm and then are uniformly mixed to obtain the traditional Chinese medicine for treating gastrorrhagia.
Example 2:
the traditional Chinese medicine for treating gastrorrhagia is prepared from the following raw materials in parts by weight: 20g of rhodomyrtus tomentosa root, 20g of red peony, 20g of copperleaf herb, 20g of herba whiskeris, 20g of white back leaf, 20g of rhizoma polygoni paleacei, 20g of uncinata spikemoss herb and 20g of toddalia asiatica.
The preparation method of the traditional Chinese medicine for treating gastrorrhagia comprises the following steps: preparing the following raw materials by weight: 20g of rhodomyrtus tomentosa root, 20g of red peony, 20g of copperleaf herb, 20g of herba whiskeris, 20g of folium Malloti Apeltae, 20g of rhizoma polygoni palustris, 20g of uncinata spikemoss herb and 20g of asiatic toddalia root, grinding the raw materials to the particle size of 1cm-2cm respectively, and mixing the raw materials uniformly to obtain the traditional Chinese medicine for treating gastrorrhagia.
Example 3:
the traditional Chinese medicine for treating gastrorrhagia is prepared from the following raw materials in parts by weight: 22g of rhodomyrtus tomentosa roots, 18g of red peony, 22g of copperleaf herb, 18g of herba whistles, 22g of gynura divaricata, 18g of rhizoma polygoni palustris, 22g of uncinata spikemoss herb and 18g of toddalia asiatica.
The preparation method of the traditional Chinese medicine for treating gastrorrhagia comprises the following steps: preparing the following raw materials by weight: 22g of rhodomyrtus tomentosa root, 18g of red peony, 22g of copperleaf herb, 18g of herba whiskeris, 22g of folium Malloti Apeltae, 18g of rhizoma polygoni palustris, 22g of uncinata spikemoss herb and 18g of asiatic toddalia root, grinding the raw materials to the particle size of 1cm-2cm respectively, and mixing the raw materials uniformly to obtain the traditional Chinese medicine for treating gastrorrhagia.
And (3) clinical observation:
the inventor carries out clinical observation treatment on 35 patients with gastrorrhagia in 2015 to date, wherein 15 male patients and 20 female patients are aged 26-65 years old.
1. Method of treatment
1 dose of the traditional Chinese medicine for treating gastrorrhagia, which is prepared in the embodiment 1, the embodiment 2 or the embodiment 3, is decocted for 2-3 times per day, 1 dose is taken for 1 day, 1 course is taken for 6 days, 1-3 courses are taken, and spicy food is avoided during the taking period. The treatment time is calculated according to the severity of the illness state of the patient, the mild patient takes about 1 course of treatment, and the severe patient can be cured after taking 3 courses of treatment.
2. Diagnostic criteria
(1) The primary diseases causing upper gastrointestinal hemorrhage, such as peptic ulcer, liver cirrhosis, chronic gastritis and stress lesion, etc.
(2) Hematemesis and/or dark stool.
(3) Corresponding manifestations may appear in different bleeding degrees, and patients with mild bleeding may have no symptoms, while patients with severe bleeding may have hemorrhagic shock.
(4) Fever, mostly below 38.5 ℃, lasts for several days to a week.
(5) Azotemia.
(6) Emergency endoscopes may show a source of blood.
3. Standard of care
(1) The effect is shown: after the patient receives 1 course of treatment, the problems of black stool, hematemesis and the like do not appear, a stool occult blood test is carried out on the patient, and the test result shows negative;
(2) the method has the following advantages: after the patient receives more than 2 courses of treatment, the symptoms of black stool and hematemesis disappear, and a stool occult blood test is carried out on the patient, and the test result shows negative;
(3) and (4) invalidation: after the patient receives more than 3 courses of treatment, the patient still has the symptoms of black stool and hematemesis, and the result is positive after receiving a stool occult blood test.
4. Clinical results
The clinical effect is 30 cases (85.72%), the effect is 3 cases (8.57%), the effect is 2 cases (5.71%), and the total effective rate is 94.29%.
5. Typical cases
Case 1: in addition, male, age 46, suffered from gastrorrhagia for 3 months, hematochezia, coffee color, epigastric pain, and tragic white face. The traditional Chinese medicine for treating gastrorrhagia, prepared in the embodiment 1, is taken for 1 dose, decocted 2-3 times a day, 1 dose in 1 day, and 1 course of treatment in 6 days. After 2 treatment courses, the symptoms are relieved, and the illness is cured after the patient continues to take the medicine for 1 treatment course. The disease does not relapse after 2 years of follow-up.
Case 2: anysome, female, age 52, with a history of duodenal ulcer, recently developed hematochezia, which was initially black and then dark red. The traditional Chinese medicine for treating gastrorrhagia, prepared in the embodiment 2 of the invention, is taken for 1 dose, decocted 2-3 times a day, 1 dose in 1 day, and 1 course of treatment for 6 days. After 2 treatment courses, the symptoms are relieved, and the illness is cured after the patient continues to take the medicine for 1 treatment course. The disease does not relapse after 1 year of follow-up visit.
Case 3: wangzhi, male, 36 years old, with irregular diet, suffered from stomachache and resulted in bleeding due to eating a lot of spicy food. The traditional Chinese medicine for treating gastrorrhagia, prepared in the embodiment 3 of the invention, is taken for 1 dose, decocted 2-3 times a day, 1 dose in 1 day, and 1 course of treatment for 6 days. After 2 treatment courses, the symptoms are relieved, and the illness is cured after the patient continues to take the medicine for 1 treatment course. No recurrence occurred during the follow-up 10 months.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims (6)

1. The traditional Chinese medicine for treating gastrorrhagia is characterized by being prepared from the following raw materials in parts by weight: 18-22g of rhodomyrtus tomentosa root, 18-22g of red peony, 18-22g of copperleaf herb, 18-22g of herba Melastomatis Cannabis, 18-22g of white backleaf, 18-22g of rhizoma polygoni paleacei, 18-22g of uncinata spikemoss herb and 18-22g of toddalia asiatica.
2. The traditional Chinese medicine for treating gastrorrhagia according to claim 1, which is prepared from the following raw materials by weight: 18g of rhodomyrtus tomentosa root, 22g of red peony, 18g of copperleaf herb, 22g of herba whiskeris, 18g of folium Malloti Apeltae, 22g of rhizoma polygoni palustris, 18g of uncinata spikemoss herb and 22g of toddalia asiatica.
3. The traditional Chinese medicine for treating gastrorrhagia according to claim 1, which is prepared from the following raw materials by weight: 20g of rhodomyrtus tomentosa root, 20g of red peony, 20g of copperleaf herb, 20g of herba whiskeris, 20g of white back leaf, 20g of rhizoma polygoni paleacei, 20g of uncinata spikemoss herb and 20g of toddalia asiatica.
4. The traditional Chinese medicine for treating gastrorrhagia according to claim 1, which is prepared from the following raw materials by weight: 22g of rhodomyrtus tomentosa roots, 18g of red peony, 22g of copperleaf herb, 18g of herba whistles, 22g of gynura divaricata, 18g of rhizoma polygoni palustris, 22g of uncinata spikemoss herb and 18g of toddalia asiatica.
5. A preparation method of a traditional Chinese medicine for treating gastrorrhagia is characterized by comprising the following steps: preparing the following raw materials by weight: 18-22g of rhodomyrtus tomentosa root, 18-22g of red peony, 18-22g of copperleaf herb, 18-22g of herba Melastomatis Cannabis, 18-22g of folium Malloti Apeltae, 18-22g of rhizoma polygoni palustris, 18-22g of uncinata spikemoss herb and 18-22g of toddalia asiatica are respectively crushed and uniformly mixed to obtain the traditional Chinese medicine for treating gastrorrhagia.
6. The method for preparing a traditional Chinese medicine for treating gastrorrhagia according to claim 5, wherein the particle size of the pulverized is 1cm-2 cm.
CN201911011939.7A 2019-10-23 2019-10-23 Traditional Chinese medicine for treating gastrorrhagia and preparation method thereof Withdrawn CN110742936A (en)

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