CN110741081B - 肿瘤选择性tata盒和caat盒突变体 - Google Patents
肿瘤选择性tata盒和caat盒突变体 Download PDFInfo
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- CN110741081B CN110741081B CN201880021788.0A CN201880021788A CN110741081B CN 110741081 B CN110741081 B CN 110741081B CN 201880021788 A CN201880021788 A CN 201880021788A CN 110741081 B CN110741081 B CN 110741081B
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- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762452075P | 2017-01-30 | 2017-01-30 | |
| US62/452,075 | 2017-01-30 | ||
| PCT/US2018/016025 WO2018140970A1 (en) | 2017-01-30 | 2018-01-30 | Tumor selective tata-box and caat-box mutants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110741081A CN110741081A (zh) | 2020-01-31 |
| CN110741081B true CN110741081B (zh) | 2024-07-23 |
Family
ID=62978967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880021788.0A Active CN110741081B (zh) | 2017-01-30 | 2018-01-30 | 肿瘤选择性tata盒和caat盒突变体 |
Country Status (14)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102089121B1 (ko) | 2013-03-14 | 2020-03-13 | 더 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 종양살상형 아데노바이러스 조성물 |
| KR20180112024A (ko) | 2016-02-23 | 2018-10-11 | 더 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 바이러스 동역학에 미치는 영향 최소화를 위한 치료용 아데노바이러스의 외인성 유전자 발현 |
| CA3013637A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| AU2017375633C1 (en) | 2016-12-12 | 2023-04-27 | Salk Institute For Biological Studies | Tumor-targeting synthetic adenoviruses and uses thereof |
| CN111133102B (zh) * | 2017-04-10 | 2024-08-16 | 埃皮辛特瑞柯斯公司 | 生产重组病毒的方法 |
| AU2019251356B2 (en) | 2018-04-09 | 2025-06-12 | Salk Institute For Biological Studies | Oncolytic adenovirus compositions with enhanced replication properties |
| EP4554559A1 (en) | 2022-07-13 | 2025-05-21 | EpicentRx, Inc. | Adenoviral vectors encapsulated in cationic liposomes, and preparation and use thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102325887A (zh) * | 2009-02-02 | 2012-01-18 | 昂克斯治疗有限公司 | 非-Ad5腺病毒载体及与其相关的方法和用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001023004A1 (en) * | 1999-09-30 | 2001-04-05 | The Trustees Of The University Of Pennsylvania | Replication selective adenoviruses for use in cancer therapy |
| EP1381276A4 (en) * | 2001-04-13 | 2005-02-02 | Univ Pennsylvania | METHOD FOR TREATMENT OR DEVELOPMENT SLUDGE DEGRADATION |
| CN1597939A (zh) * | 2001-11-15 | 2005-03-23 | 杭州中肽生化有限公司 | 多功能抗癌重组腺病毒 |
| CN101319215B (zh) * | 2008-07-01 | 2010-12-22 | 郑骏年 | 人肿瘤特异性Ki67基因启动子 |
| DK3029144T3 (da) * | 2009-03-02 | 2019-10-21 | Univ California | Tumorselektive adenovirus e1a- og e1b-mutanter |
| EP2784155B1 (en) * | 2011-11-24 | 2018-06-13 | Viromed Co. Ltd. | Adenovirus producing novel cell line and the use thereof |
| FI123955B (en) * | 2011-11-25 | 2014-01-15 | Oncos Therapeutics Ltd | Oncolytic adenovirus |
| US20140350087A9 (en) * | 2012-03-22 | 2014-11-27 | Halozyme, Inc. | Oncovector Nucleic Acid Molecules and Methods of Use |
| CA3190510A1 (en) | 2014-07-16 | 2016-01-21 | Transgene Sa | Oncolytic virus for expression of immune checkpoint modulators |
| JP7216668B2 (ja) * | 2017-05-26 | 2023-02-01 | エピセントアールエックス,インコーポレイテッド | 導入遺伝子を保持する組換えアデノウイルス |
-
2018
- 2018-01-30 BR BR112019015514A patent/BR112019015514A2/pt unknown
- 2018-01-30 EP EP18744813.9A patent/EP3573632B1/en active Active
- 2018-01-30 IL IL268289A patent/IL268289B2/en unknown
- 2018-01-30 CA CA3052086A patent/CA3052086A1/en active Pending
- 2018-01-30 AU AU2018212017A patent/AU2018212017B2/en active Active
- 2018-01-30 US US16/482,049 patent/US20190352669A1/en not_active Abandoned
- 2018-01-30 WO PCT/US2018/016025 patent/WO2018140970A1/en not_active Ceased
- 2018-01-30 EA EA201991806A patent/EA201991806A1/ru unknown
- 2018-01-30 KR KR1020237040310A patent/KR102880548B1/ko active Active
- 2018-01-30 KR KR1020197025497A patent/KR102607220B1/ko active Active
- 2018-01-30 CN CN201880021788.0A patent/CN110741081B/zh active Active
- 2018-01-30 JP JP2019541082A patent/JP7242534B2/ja active Active
- 2018-01-30 SG SG11201906976YA patent/SG11201906976YA/en unknown
- 2018-01-30 MX MX2019008922A patent/MX2019008922A/es unknown
-
2019
- 2019-07-31 ZA ZA2019/05070A patent/ZA201905070B/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102325887A (zh) * | 2009-02-02 | 2012-01-18 | 昂克斯治疗有限公司 | 非-Ad5腺病毒载体及与其相关的方法和用途 |
Non-Patent Citations (3)
| Title |
|---|
| Adenoviral expression vector Ad-hiNOS;Shapiro,R.等;《Genbank》;20010917;2 * |
| Shapiro,R., Gao,W., Tzeng,E., Robbins,P.D., Timoty,B.R. and Gamb.Adenoviral expression vector Ad-hiNOS.《Genbank》.2001,1-8. * |
| Timothy F. Osborne 等.The TATA homology and the mRNA 5' untranslated sequence are not required for expression of essential adenovirus E1A functions.Cell.1982,第29卷第139-148页,特别是摘要. * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP7242534B2 (ja) | 2023-03-20 |
| JP2020505046A (ja) | 2020-02-20 |
| IL268289B2 (en) | 2025-09-01 |
| AU2018212017B2 (en) | 2024-11-28 |
| WO2018140970A1 (en) | 2018-08-02 |
| KR20230164231A (ko) | 2023-12-01 |
| SG11201906976YA (en) | 2019-08-27 |
| CN110741081A (zh) | 2020-01-31 |
| EP3573632B1 (en) | 2024-08-07 |
| EA201991806A1 (ru) | 2020-02-13 |
| AU2018212017A1 (en) | 2019-08-15 |
| EP3573632A1 (en) | 2019-12-04 |
| CA3052086A1 (en) | 2018-08-02 |
| ZA201905070B (en) | 2024-12-18 |
| EP3573632C0 (en) | 2024-08-07 |
| KR102880548B1 (ko) | 2025-11-05 |
| KR20190128633A (ko) | 2019-11-18 |
| US20190352669A1 (en) | 2019-11-21 |
| KR102607220B1 (ko) | 2023-12-01 |
| MX2019008922A (es) | 2020-01-20 |
| IL268289B1 (en) | 2025-05-01 |
| EP3573632A4 (en) | 2020-09-23 |
| BR112019015514A2 (pt) | 2020-04-07 |
| IL268289A (en) | 2019-09-26 |
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