CN110684083A - 抑制黑色素合成的偶联物ii及其在药品和化妆品中的应用 - Google Patents
抑制黑色素合成的偶联物ii及其在药品和化妆品中的应用 Download PDFInfo
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- CN110684083A CN110684083A CN201911245149.5A CN201911245149A CN110684083A CN 110684083 A CN110684083 A CN 110684083A CN 201911245149 A CN201911245149 A CN 201911245149A CN 110684083 A CN110684083 A CN 110684083A
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Birds (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cosmetics (AREA)
Abstract
Description
有效人数 | 有效率 | |
美白 | 28 | 93.3% |
Claims (7)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201911245149.5A CN110684083B (zh) | 2019-12-06 | 2019-12-06 | 抑制黑色素合成的偶联物ii及其在药品和化妆品中的应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201911245149.5A CN110684083B (zh) | 2019-12-06 | 2019-12-06 | 抑制黑色素合成的偶联物ii及其在药品和化妆品中的应用 |
Publications (2)
Publication Number | Publication Date |
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CN110684083A true CN110684083A (zh) | 2020-01-14 |
CN110684083B CN110684083B (zh) | 2020-05-15 |
Family
ID=69117735
Family Applications (1)
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CN201911245149.5A Active CN110684083B (zh) | 2019-12-06 | 2019-12-06 | 抑制黑色素合成的偶联物ii及其在药品和化妆品中的应用 |
Country Status (1)
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CN (1) | CN110684083B (zh) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009044162A1 (en) * | 2007-10-05 | 2009-04-09 | Cancer Research Technology Limited | Pyrazin-2-yl-pyridin-2-yl-amine and pyrazin-2-yl-pyrimidin-4-yl-amine compounds and their use |
WO2013171470A1 (en) * | 2012-05-15 | 2013-11-21 | Cancer Research Technology Limited | 5-[[4-[[morpholin-2-yl]methylamino]-5-(trifluoromethyl)-2-pyridyl]amino]pyrazine-2-carbonitrile and therapeutic uses thereof |
-
2019
- 2019-12-06 CN CN201911245149.5A patent/CN110684083B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009044162A1 (en) * | 2007-10-05 | 2009-04-09 | Cancer Research Technology Limited | Pyrazin-2-yl-pyridin-2-yl-amine and pyrazin-2-yl-pyrimidin-4-yl-amine compounds and their use |
WO2013171470A1 (en) * | 2012-05-15 | 2013-11-21 | Cancer Research Technology Limited | 5-[[4-[[morpholin-2-yl]methylamino]-5-(trifluoromethyl)-2-pyridyl]amino]pyrazine-2-carbonitrile and therapeutic uses thereof |
CN106279142A (zh) * | 2012-05-15 | 2017-01-04 | 癌症研究技术有限公司 | 5‑[[4‑[[吗啉‑2‑基]甲基氨基]‑5‑(三氟甲基)‑2‑吡啶基]氨基]吡嗪‑2‑腈及其治疗应用 |
Non-Patent Citations (1)
Title |
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马严: "可在体实现胞内直接投递的新型细胞穿膜肽的构建、筛选和穿膜机制研究", 《中国博士学位论文全文数据库(电子期刊)》 * |
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Publication number | Publication date |
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CN110684083B (zh) | 2020-05-15 |
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Address after: 100176 room 801, 8th floor, building 2, yard 5, Ronghua Middle Road, Beijing Economic and Technological Development Zone, Daxing District, Beijing Patentee after: Beijing Daxi Biotechnology Co.,Ltd. Address before: 100010 1408, 14th floor, building 1, yard 5, Ronghua Middle Road, Beijing Economic and Technological Development Zone, Daxing District, Beijing Patentee before: Beijing Northai Research Institute of Regenerative Medicine Co.,Ltd. |
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Effective date of registration: 20210122 Address after: 100176 room 01-12, 1st floor, building 1, No.3, Yongchang North Road, Beijing Economic and Technological Development Zone, Daxing District, Beijing Patentee after: Nuosa Union (Beijing) Biomedical Technology Co.,Ltd. Patentee after: Beijing Daxi Biotechnology Co.,Ltd. Address before: 100176 room 801, 8th floor, building 2, yard 5, Ronghua Middle Road, Beijing Economic and Technological Development Zone, Daxing District, Beijing Patentee before: Beijing Daxi Biotechnology Co.,Ltd. |
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