CN110664787A - 右美托咪定缓释微针阵列及其制备方法 - Google Patents
右美托咪定缓释微针阵列及其制备方法 Download PDFInfo
- Publication number
- CN110664787A CN110664787A CN201910976803.3A CN201910976803A CN110664787A CN 110664787 A CN110664787 A CN 110664787A CN 201910976803 A CN201910976803 A CN 201910976803A CN 110664787 A CN110664787 A CN 110664787A
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- Prior art keywords
- dexmedetomidine
- microneedle array
- pharmaceutically acceptable
- microneedle
- auxiliary materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Pain & Pain Management (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201910976803.3A CN110664787B (zh) | 2019-10-15 | 2019-10-15 | 右美托咪定缓释微针阵列及其制备方法 |
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CN201910976803.3A CN110664787B (zh) | 2019-10-15 | 2019-10-15 | 右美托咪定缓释微针阵列及其制备方法 |
Publications (2)
Publication Number | Publication Date |
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CN110664787A true CN110664787A (zh) | 2020-01-10 |
CN110664787B CN110664787B (zh) | 2022-05-27 |
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CN201910976803.3A Active CN110664787B (zh) | 2019-10-15 | 2019-10-15 | 右美托咪定缓释微针阵列及其制备方法 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN117771220A (zh) * | 2024-02-28 | 2024-03-29 | 山东第二医科大学 | 一种右美托咪定中药多糖口溶膜剂及其制备方法和应用 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012122162A1 (en) * | 2011-03-07 | 2012-09-13 | 3M Innovative Properties Company | Microneedle devices and methods |
CN106422045A (zh) * | 2016-09-05 | 2017-02-22 | 中国科学院理化技术研究所 | 一种柔曲性缓释微针贴片及其制备方法 |
CN110114069A (zh) * | 2016-12-26 | 2019-08-09 | 久光制药株式会社 | 微针装置 |
-
2019
- 2019-10-15 CN CN201910976803.3A patent/CN110664787B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012122162A1 (en) * | 2011-03-07 | 2012-09-13 | 3M Innovative Properties Company | Microneedle devices and methods |
CN106422045A (zh) * | 2016-09-05 | 2017-02-22 | 中国科学院理化技术研究所 | 一种柔曲性缓释微针贴片及其制备方法 |
CN110114069A (zh) * | 2016-12-26 | 2019-08-09 | 久光制药株式会社 | 微针装置 |
Non-Patent Citations (2)
Title |
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I.-CHI LEE等: "Fabrication of a novel partially dissolving polymer microneedle patch for transdermal drug delivery", 《JOURNAL OF MATERIALS CHEMISTRY B》 * |
赵笑等: "聚合物微针介导经皮给药的研究", 《化学进展》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN117771220A (zh) * | 2024-02-28 | 2024-03-29 | 山东第二医科大学 | 一种右美托咪定中药多糖口溶膜剂及其制备方法和应用 |
CN117771220B (zh) * | 2024-02-28 | 2024-05-28 | 山东第二医科大学 | 一种右美托咪定中药多糖口溶膜剂及其制备方法和应用 |
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CN110664787B (zh) | 2022-05-27 |
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Effective date of registration: 20200903 Address after: 350005 No. 20 Cha Zhong Road, Fuzhou, Fujian Applicant after: THE FIRST AFFILIATED HOSPITAL OF FUJIAN MEDICAL University Address before: No. 134 Dongjie, Fuzhou City, Fujian Province, 350000 Applicant before: FUJIAN PROVINCIAL Hospital Applicant before: THE FIRST AFFILIATED HOSPITAL OF FUJIAN MEDICAL University |
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CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: Zeng Kai Inventor after: Wu Xiaodan Inventor after: Zhong Xincheng Inventor after: Tang Yijie Inventor before: Wu Xiaodan Inventor before: Zeng Kai Inventor before: Zhong Xincheng Inventor before: Tang Yijie |
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