CN110582271B - 包含pgi2受体激动剂的组合物及其制备方法 - Google Patents
包含pgi2受体激动剂的组合物及其制备方法 Download PDFInfo
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- CN110582271B CN110582271B CN201880029276.9A CN201880029276A CN110582271B CN 110582271 B CN110582271 B CN 110582271B CN 201880029276 A CN201880029276 A CN 201880029276A CN 110582271 B CN110582271 B CN 110582271B
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- A—HUMAN NECESSITIES
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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- Pharmacology & Pharmacy (AREA)
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- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Inorganic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762465675P | 2017-03-01 | 2017-03-01 | |
| US62/465,675 | 2017-03-01 | ||
| US201762468832P | 2017-03-08 | 2017-03-08 | |
| US62/468,832 | 2017-03-08 | ||
| US201762526039P | 2017-06-28 | 2017-06-28 | |
| US62/526,039 | 2017-06-28 | ||
| US201762530515P | 2017-07-10 | 2017-07-10 | |
| US62/530,515 | 2017-07-10 | ||
| PCT/US2018/020519 WO2018160882A1 (en) | 2017-03-01 | 2018-03-01 | Compositions comprising pgi2-receptor agonists and processes for the preparation thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110582271A CN110582271A (zh) | 2019-12-17 |
| CN110582271B true CN110582271B (zh) | 2022-06-14 |
Family
ID=61622823
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880029276.9A Active CN110582271B (zh) | 2017-03-01 | 2018-03-01 | 包含pgi2受体激动剂的组合物及其制备方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US11123298B2 (enExample) |
| EP (2) | EP3977985B1 (enExample) |
| JP (2) | JP7023559B2 (enExample) |
| KR (2) | KR20220119169A (enExample) |
| CN (1) | CN110582271B (enExample) |
| AU (2) | AU2018227842B2 (enExample) |
| CA (1) | CA3054835A1 (enExample) |
| ES (2) | ES2897024T3 (enExample) |
| IL (1) | IL268997B2 (enExample) |
| MA (1) | MA47686A (enExample) |
| WO (1) | WO2018160882A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102441249B1 (ko) | 2014-10-23 | 2022-09-08 | 아레나 파마슈티칼스, 인크. | Pgi2 수용체 관련 병태의 치료 방법 |
| KR20220119169A (ko) | 2017-03-01 | 2022-08-26 | 아레나 파마슈티칼스, 인크. | Pgi2-수용체 효능제를 포함하는 조성물 및 그의 제조 방법 |
| EP3796902A1 (en) | 2018-05-16 | 2021-03-31 | Arena Pharmaceuticals, Inc. | Compositions comprising pgi2-receptor agonists and processes for the preparation thereof |
| WO2023158634A1 (en) | 2022-02-15 | 2023-08-24 | United Therapeutics Corporation | Crystalline prostacyclin (ip) receptor agonist and uses thereof |
| KR20250008015A (ko) * | 2023-07-06 | 2025-01-14 | 재단법인대구경북과학기술원 | 셀렉시팍을 포함하는 퇴행성 뇌질환의 예방 또는 치료용 약학 조성물 |
| WO2025193579A1 (en) | 2024-03-11 | 2025-09-18 | United Therapeutics Corporation | Methods of making ip-receptor agonists |
Citations (3)
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|---|---|---|---|---|
| CN102036659A (zh) * | 2008-03-18 | 2011-04-27 | 艾尼纳制药公司 | 用于治疗前列环素(pgi2)受体相关病症的pgi2受体调节剂 |
| CN102292321A (zh) * | 2008-11-26 | 2011-12-21 | 艾尼纳制药公司 | 作为前列环素(pgi2)受体调节剂用于治疗该受体相关病症的吡唑基取代的碳酸衍生物 |
| WO2016065103A1 (en) * | 2014-10-23 | 2016-04-28 | Arena Pharmaceuticals, Inc. | Method of treating conditions related to the pgi2 receptor |
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| KR20220119169A (ko) | 2017-03-01 | 2022-08-26 | 아레나 파마슈티칼스, 인크. | Pgi2-수용체 효능제를 포함하는 조성물 및 그의 제조 방법 |
| EP3796902A1 (en) | 2018-05-16 | 2021-03-31 | Arena Pharmaceuticals, Inc. | Compositions comprising pgi2-receptor agonists and processes for the preparation thereof |
-
2018
- 2018-03-01 KR KR1020227027530A patent/KR20220119169A/ko not_active Ceased
- 2018-03-01 EP EP21192192.9A patent/EP3977985B1/en active Active
- 2018-03-01 CA CA3054835A patent/CA3054835A1/en active Pending
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| CN103483226A (zh) * | 2008-03-18 | 2014-01-01 | 艾尼纳制药公司 | 用于治疗前列环素(pgi2)受体相关病症的pgi2受体调节剂 |
| CN104262267A (zh) * | 2008-03-18 | 2015-01-07 | 艾尼纳制药公司 | 用于治疗前列环素(pgi2)受体相关病症的pgi2受体调节剂 |
| CN102292321A (zh) * | 2008-11-26 | 2011-12-21 | 艾尼纳制药公司 | 作为前列环素(pgi2)受体调节剂用于治疗该受体相关病症的吡唑基取代的碳酸衍生物 |
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Also Published As
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| WO2018160882A1 (en) | 2018-09-07 |
| EP3589274A1 (en) | 2020-01-08 |
| MA47686A (fr) | 2021-05-12 |
| EP3977985A1 (en) | 2022-04-06 |
| JP2022070923A (ja) | 2022-05-13 |
| CA3054835A1 (en) | 2018-09-07 |
| KR102432505B1 (ko) | 2022-08-12 |
| JP2020510660A (ja) | 2020-04-09 |
| EP3589274B1 (en) | 2021-10-13 |
| IL268997B1 (en) | 2023-05-01 |
| US11826471B2 (en) | 2023-11-28 |
| CN110582271A (zh) | 2019-12-17 |
| JP7498202B2 (ja) | 2024-06-11 |
| JP7023559B2 (ja) | 2022-02-22 |
| IL268997B2 (en) | 2023-09-01 |
| EP3977985B1 (en) | 2023-09-06 |
| KR20190124261A (ko) | 2019-11-04 |
| AU2018227842A1 (en) | 2019-09-19 |
| US20190240159A1 (en) | 2019-08-08 |
| KR20220119169A (ko) | 2022-08-26 |
| ES2965069T3 (es) | 2024-04-11 |
| US11123298B2 (en) | 2021-09-21 |
| US20210378965A1 (en) | 2021-12-09 |
| AU2018227842B2 (en) | 2024-05-02 |
| AU2024203156A1 (en) | 2024-05-30 |
| IL268997A (en) | 2019-10-31 |
| US20240285537A1 (en) | 2024-08-29 |
| ES2897024T3 (es) | 2022-02-28 |
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