CN110522890A - Prevent and treat chicken rhinitis and the Chinese herbal feed additive of protozoosis and preparation method thereof - Google Patents

Prevent and treat chicken rhinitis and the Chinese herbal feed additive of protozoosis and preparation method thereof Download PDF

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CN110522890A
CN110522890A CN201910753329.8A CN201910753329A CN110522890A CN 110522890 A CN110522890 A CN 110522890A CN 201910753329 A CN201910753329 A CN 201910753329A CN 110522890 A CN110522890 A CN 110522890A
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feed additive
chinese herbal
herbal feed
chinese
protozoosis
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CN110522890B (en
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张冰坤
吴洁
卢寿运
何陈灿
沈永强
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GUANGDONG GAOSHAN ANIMAL MEDICINE CO Ltd
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GUANGDONG GAOSHAN ANIMAL MEDICINE CO Ltd
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Abstract

The purpose of the present invention is to propose to a kind of prevention and treatment chicken rhinitis and the Chinese herbal feed additive of protozoosis and preparation method thereof, which can reduce medicament residue, improve the quality of chicken and egg, and then improve culture efficiency.The Chinese herbal feed additive of prevention and treatment chicken rhinitis and protozoosis of the invention is mixed by raw material Chinese medicine according to following portions by weight ratio: cloves 7~10, rhizoma zingiberis 7~10, Chinese torreyanut 10~15, Lappula echinata 10~15, stone-like omphalia 8~10, dandelion 15~18, betel nut 5~8, cordate houttuynia 10~12, hairyvein agrimony 10~12, Radix Astragali 35~40.Above-mentioned Chinese herbal feed additive can drive away the various protozoosises of chicken, and concurrent bacterium, viral disease with rhinitis, it effectively prevent laying rate to decline, Egg Quality is improved, kills, the harmful bacteria in inhibition body, maintains body bacterium colony balance, improve the immunity of body, the development for controlling epidemic situation, reduces epidemic disease palindromia, and preferable control efficiency is obtained from implementation.

Description

Prevent and treat chicken rhinitis and the Chinese herbal feed additive of protozoosis and preparation method thereof
Technical field
The invention belongs to cultivate and field of feed, and in particular to arrive a kind of Chinese herbal feed additive and its preparation side Method.
Background technique
Infectious coryza of chicken is as caused by haemophilus, is the mainly young chicken of special disease and production with eye and schneiderian membrane inflammation The acute upper respiratory tract infection of laying hen.Chicken leucocyte protozoon be by colonize in chicken blood monocyte and it is endoerythrocytic live A kind of parasitic disease caused by leukocytozoon.The cause of disease of this disease is a kind of sporozoite, and infected chicken mainly has Sharpe to live white worm White worm is lived with Cattell, but most of lived caused by white worm as Cattell.The disease is characterized by internal organs and hemorrhage of muscle, performance It is pale for cockscomb, so being called " white comb ".Above two disease is chicken infectious disease more typical in farm, is easy to cause chicken Hypoevolutism, activity are difficult, or even cause chicken group dead.
Farm uses west drug generally to treat infectious coryza of chicken and chicken leucocyte protozoon at present, such as says The treatment for carrying out infectious coryza of chicken is generally shared with Compound New Nomin or trimethoprim (TMP) and other sulfa drugs, using sulphur Amine hexakis-methoxy pyrimidine treats chicken leucocyte protozoon, and the method for injection, generally selection strepto- are also taken through common antibiotics Element or penicillin, streptomysin merge application.But above-mentioned therapeutic modality is easy to cause medicament residue in chicken, is unable to satisfy people To the increasingly higher demands of chicken, egg quality, it is therefore necessary to which researching and developing one kind can treat infectious coryza of chicken, while again Reduction or the not therapeutic modality of medicament residue.
Summary of the invention
The purpose of the present invention is to propose to a kind of prevention and treatment chicken rhinitis and the Chinese herbal feed additive of protozoosis and preparation method thereof, The Chinese herbal feed additive can reduce medicament residue, improve the quality of chicken and egg, and then improve culture efficiency.
The Chinese herbal feed additive of prevention and treatment chicken rhinitis and protozoosis of the invention is by raw material Chinese medicine according to following portions by weight Than mixing: cloves 7~10, rhizoma zingiberis 7~10, Chinese torreyanut 10~15, Lappula echinata 10~15, stone-like omphalia 8~10, dandelion 15~18, Betel nut 5~8, cordate houttuynia 10~12, hairyvein agrimony 10~12, Radix Astragali 35~40.
Preferably, above-mentioned Chinese herbal feed additive is mixed by raw material Chinese medicine according to following portions by weight ratio: cloves 10, Rhizoma zingiberis 10, Chinese torreyanut 15, Lappula echinata 15, stone-like omphalia 10, dandelion 18, betel nut 8, cordate houttuynia 12, hairyvein agrimony 12, Radix Astragali 40.
The preparation method of the Chinese herbal feed additive of above-mentioned prevention and treatment chicken rhinitis and protozoosis includes the following steps:
A, various raw material Chinese medicines are also known as taken into predetermined weight number;
B, it takes cloves, rhizoma zingiberis, betel nut, cordate houttuynia to mix and is distilled, obtain volatile oil and the dregs of a decoction;
C, the above-mentioned dregs of a decoction are mixed with Chinese torreyanut, Lappula echinata, stone-like omphalia, dandelion, hairyvein agrimony and adds water to cook secondary, will decocted twice To medical fluid mixing, concentration, stand after obtain mixing supernatant;
D, Radix Astragali is added water to cook three times, the medical fluid decocted three times is mixed, be concentrated, obtains Radix Astragali supernatant after standing;
E, oil, mixing supernatant and Radix Astragali supernatant be will volatilize and be mixed to get the Chinese herbal feed additive.
Cloves is the dry flower of plant clove of myrtaceae Eugenia caryophllata Thunb., and property is acrid in flavour and warm in nature, Enter stomach, spleen, kidney channel.This product have antibacterial action, antifungic action, anthelmintic action, digestion promoting function, analgesic effect, resist oxygen lack and by Cold equal influence and other effects.It is dropped with middle benefit gas inverse;The functions such as warming kidney and enhancing yang.Cure mainly main hiccup;Coldness and pain in the epigastrium;Deficiency of food leaf rushes down;Kidney Empty impotence;Waist and knee acid is cold;Negative subcutaneous ulcer.
Rhizoma zingiberis is the dry rhizome of zingiber Zingiber officinale Rosc..It is sweet in flavor, it is mild-natured.Acrid flavour, property Heat.Returns spleen, stomach, the heart, lung channel.This product has analgesia, anti-inflammatory, resistant to aggregation, antibacterial, antiprotozoan effect, anti anoxia, irritability stomach to burst Ulcer/acetic acid, which induces gastric ulcer/Pylorus Ligated Gastric Ulcer, obvious inhibiting effect.With warming spleen and stomach for dispelling cold, recover Yang and smooth venation, eliminating dampness Dissolving phlegm, the functions such as warming lung and resolving fluid.Cure mainly coldness and pain in the epigastrium;Vomiting;Diarrhea, yang depletion are fainted inverse;Cold drink is breathed with cough;Numbness and ache of cold dampness.
Chinese torreyanut is the dry mature seed of taxaceae plant Chinese torreya Torreya grandis Fort..Nature and flavor sweet and neutral.Return Lung, stomach, large intestine channel.With killing insect and eliminating accumulation, the functions such as moistening dryness for relaxing bowels.For abdominal pain due to enterositosis, constipation.
Lappula echinata is the dry mature fruit of compositae plant day name essence Carpesium abrotanoides L..Nature and flavor are returned Through: it is flat;It is bitter, pungent;Returns spleen, stomach meridian.In fruit containing valeric acid, n-caproic acid, oleic acid, dextrorotation linolenic acid, 1 alkane, stigmasterol and The lactone compounds such as carpesia-lactone, carabrone.Seed contains torilin.FRUCTUS LAPPULAE ECHINATAE seed oil content 19.48%.Fruit contains Volatile oil, oil in contain carpesia-lactone and carabrone;Shang Hanzheng acid, stigmasterol, melissane and hentriacontane etc..With killing Worm, clearing heat and detoxicating, strengthening the spleen and stomach and other effects.
Stone-like omphalia is the dry sclerotia of Tricholomataceae fungi stone-like omphalia Omphalia lapidescens Schroet..Nature and flavor are returned Through: bitter is trembled with fear, slightly poisonous.With disperse accumulation, desinsection.Control abdominal pain due to enterositosis, infantile malnutrition due to digestive disturbances or intestinalparasites disease, the functions such as wind epilepsy.Tapeworm can be treated, inhaled Worm, around worm.1, to having hook and Taenia mediocanellata, Taenia elliptica has anthelmintic action.The effect of stone-like omphalia expelling tenia is not paralysis polypide, and It is the decomposition due to the protease in stone-like omphalia to protein, caused by causing worm section to destroy.2. the effect of pair roundworm: experiment in vitro pair Ascaris suum is effective, but invalid to roundworm infection person.3. the effect of anti-trichomonas vaginalis: 10% stone-like omphalia decoction, medical fluid and culture Base is at the concentration of 1:1, and most of polypide granulating deformation, individual polypides still have activity after five minutes.4. other are acted on: stone-like omphalia pair Leech and earthworm have more significant insecticidal action.Experiment shows: stone-like omphalia Polysaccharides on Mice croton oil otitis disease, rat agar There is obvious inhibiting effect with yeast swollen joint;There is humidification to body non-specificity and specific immune function.Stone-like omphalia Element has certain inhibiting effect to mouse S180 and W256.
Dandelion is compositae plant dandelion Taraxacum mongolicum Hand.-Mazz., alkali ground dandelion Taraxacum sinicum Kitag. or the drying herb for belonging to several plants.It is bitter in taste, sweet, it trembles with fear.Return liver, stomach meridian.This product Rich in vitamin A, vitamin C and potassium, also contain iron, calcium, vitamin B2, vitamin B1, magnesium, vitamin B6, folic acid and copper.Pu Contain a variety of health-nutrition ingredients such as taraxol, taraxacin, choline, organic acid, synanthrin in public English plant.Nature and flavor are sweet, Slight bitter is trembled with fear.Return liver, stomach meridian.There are diuresis, laxative, removing jaundice subcutaneous ulcer, cholagogue and other effects.It is swollen to control heat toxin, carbuncle swells, sore, internal carbuncle, hot eyes Bitterly, the puckery pain of damp and hot, jaundice, dribbling urination, furuncle swelling toxin, acute mastitis, scrofula, toothache, hot eyes, pharyngalgia, pulmonary abscess, acute appendicitis, damp and hot Huang Subcutaneous ulcer, puckery pain of heat gonorrhea.Control acute mastitis, adenolymphitis, scrofula, boil poisonous soreness, acute conjunctivitis, cold, fever, acute almond Body is scorching, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infections etc.
Betel nut is the dry mature seed of babassu betel nut Areca catechu L..It is bitter in taste, acrid in flavour and warm in nature.Return stomach, big Intestines warp.Major function killing insect and eliminating accumulation, sending down abnormally ascending, row water, preventing malaria.For tapeworm, roundworm, fasciolopsiasis, abdominal pain due to enterositosis is stagnant to rush down Dysentery, tenesmus, oedema tinea pedis, malaria.
Cordate houttuynia is the dry aerial parts of saururaceae plant houttuynia cordata Houttuynia cordata Thunb..Taste It is pungent, it is cold, it is distributed in lung channel.Can clearing heat and detoxicating, detumescence treat sore, promoting urination and removing dampness, clearing away heat to cure dysentery, stomach strengthening and digestion promoting, with controlling real heat, heat Poison, damp evil, disease heat are pulmonary abscess, sore swollen toxin, hemorrhoidal hemorrhage, the retention of heat in the spleen and stomach etc. suffered from.Modern pharmacology experiment shows that this product has Antibacterial, it is antiviral, improve immunity of organisms, diuresis the effects of.
Hairyvein agrimony is the dry aerial parts of rosaceous plant hairyvein agrimony Agrimonia pilosa Ledeb..Nature and flavor It is bitter, puckery, it puts down.Converge to heart and liver channels.Astringing to arrest bleeding, preventing malaria, stop dysentery, removing toxic substances.For hemoptysis, spit blood, metrostaxis, malaria, bloody flux, De-power internal lesion caused by overexertion, carbuncle sore tumefacting virus.
Radix Astragali is the root of leguminous perennial herb Radix Astragali and Inner Mongolia Astragalis, is a kind of common tonifying middle-Jiao and Qi medicine, property is micro- Temperature, sweet in flavor, returns spleen, lung channel have tonifying Qi and lifting yang, strengthening exterior and reducing sweat, promoting pus discharge and tissue regeneration and inducing diuresis for removing edema and other effects.Its main component is Astragalus polyose, Astragaloside IV, flavone compound etc..A large amount of clinical tests prove, Radix Astragali has cardioprotection and kidney, two-way The effects of adjusting blood glucose and blood pressure, anti anoxia, free radical resisting oxidation and enhancing immunity of organisms.Radix Astragali also has the anti-of wide spectrum Virus function also has certain inhibiting effect to lesion caused by oral cavity virus and influenza celestial platform BBI virus;Radix Astragali is to dysentery bar Bacterium, Diplococcus pneumopniae, hemolytic streptococcus and staphylococcus aureus, lemon yellow and staphylococcus albus etc. have inhibition to make With.
The present invention mainly according to Chinese medicine rising Yang drop inverse, expelling parasite, hemostasis, promoting the circulation of qi, tonifying Qi, improve immunity of organisms, antibacterial, The research of the effects of antiviral and mechanism has in prescription with cloves, rhizoma zingiberis, Chinese torreyanut, Lappula echinata, stone-like omphalia, betel nut and drives away different portions The effects of protozoon, promoting the circulation of qi, change product, preventing or arresting vomiting of position etc. are the monarch drug in a prescription of antiprotozoan, are stopped blooding using hairyvein agrimony is ministerial drug, cloves rising Yang drop Inverse, antibacterial is adjutant, and the Radix Astragali reparation mucous membrane impaired because of body caused by protozoon, raisings immunity of organisms is adjuvant.Fourth simultaneously It is monarch drug in a prescription that perfume, rhizoma zingiberis, cordate houttuynia, dandelion, which are rhinitis with antibacterial, antiviral etc., has tonifying Qi and lifting yang with Radix Astragali, Gu table stops It is adjutant that sweat, promoting pus discharge and tissue regeneration and inducing diuresis for removing edema etc., which improve immunity of organisms,.Prescription shares,
In Production of Livestock and Poultry, " tiger " is visible to be prevented;And " small worm (medical protozoon) " is not clear to or sees, has become " disease ", to production Influence and caused by lose it is bigger!Traditional antibiotic treatment mode is anti-" tiger " and controls " small worm ";And use the present invention Pure Chinese medicine feed addictive, " tiger " and " small worm " can be prevented simultaneously.
Above-mentioned Chinese herbal feed additive is clinically used for poultry, can drive away various protozoosises, and concurrent with rhinitis Bacterium, viral disease, effectively prevent laying rate to decline, improve Egg Quality, kill, the harmful bacteria in inhibition body, maintain machine Body bacterium colony balance, improve the immunity of body, control the development of epidemic situation, reduce epidemic disease palindromia, and from implementation obtain compared with Good control efficiency.Since feed addictive is made of pure Chinese medicine, medicament residue will not be caused, it is ensured that chicken and egg Quality.
Specific embodiment
Below by the description to embodiment, to the shape of for example related each component of a specific embodiment of the invention The works such as shape, construction, the mutual alignment between each section and connection relationship, the effect of each section and working principle are further detailed Explanation.
Embodiment 1:
The present embodiment proposes a kind of prevention and treatment chicken rhinitis and the Chinese herbal feed additive of protozoosis and preparation method thereof, which raises Feed additives can reduce medicament residue, improve the quality of chicken and egg, and then improve culture efficiency.
The Chinese herbal feed additive for preventing and treating chicken rhinitis and protozoosis of the present embodiment is by raw material Chinese medicine according to following weight parts Number ratio mixes: cloves 10, rhizoma zingiberis 10, Chinese torreyanut 15, Lappula echinata 15, stone-like omphalia 10, dandelion 18, betel nut 8, cordate houttuynia 12, red crowned crane Careless 12, Radix Astragali 40.
The preparation method of above-mentioned Chinese herbal feed additive includes the following steps:
A, various raw material Chinese medicines are also known as taken into predetermined weight number;
B, it takes cloves, rhizoma zingiberis, betel nut, cordate houttuynia to mix and carries out second distillation, it is dilute to lead to steam distillation acquirement concentration for the first time Distillate adds water and carries out second of distillation again, and contained volatility active principle is extracted to greatest extent, collects twice Distillate mixing and obtain the volatile oil of high-purity, the surplus materials after distillation is the dregs of a decoction;
C, the above-mentioned dregs of a decoction are mixed and is added water to cook with Chinese torreyanut, Lappula echinata, stone-like omphalia, dandelion, hairyvein agrimony, medical fluid is obtained by filtration and mixed The dregs of a decoction are closed, then the mixing dregs of a decoction are added water to cook for the second time, medical fluid is obtained by filtration;The medical fluid obtained twice is mixed, concentration, is stood After obtain mixing supernatant;
D, according to method described in step C, Radix Astragali is added water to cook three times, the medical fluid decocted three times is mixed, is concentrated, is quiet It postpones to obtain Radix Astragali supernatant;
E, oil, mixing supernatant and Radix Astragali supernatant be will volatilize and be mixed to get the Chinese herbal feed additive.
During above-mentioned preparation method, by the method for second distillation, it is sufficiently extracted cloves, rhizoma zingiberis, betel nut, fish Effective ingredient --- volatile oil in raw meat grass;If the method for not using second distillation, common decoction extracting method can make to wave Hair oil vapors away, and loses the effective ingredient in formula.In addition, the dregs of a decoction after distillation is extracted are mixed with other Chinese medicines again It closes and decocts, water soluble drug effective ingredient therein can be extracted, thus substantially increased to cloves, rhizoma zingiberis, betel nut, fish raw meat The utilization rate of effective ingredient in grass, and then enhance the whole drug effect of Chinese herbal feed additive.
The Chinese herbal feed additive of the present embodiment is the natural plants joint product of new generation combined through special process, dashes forward Broken the temperature of prescription natural plants, heat, cold, four cool bias, belonged in pharmacological property without acute levelling, can in breeding production the stage Property or regular health care addition, can have alleviate poultry rhinitis and release protozoon (such as white comb) malnutrition due to parasitic infestation card double effects, energy It is effectively relieved all caused by the single or mixed infections such as poultry acute and chronic respiratory diseases, infective rhinitis and infective bronchitis Card.Card see breathing rale, dehisce to stretch neck breathing, face swelling, nose is swollen, eye is swollen, nasal sinus stores purulence and nostril outflow serosity, glues Fluidity to purulence stench secretion etc.;Internal enteron parasite (including coccidia) can be effectively released, especially organizer is dirty Interior protozoon, such as the white firmly all cards of card cell worm (white comb) malnutrition due to parasitic infestation;Endotoxin can be removed, inferior health is released, improves production performance, It interim in breeding production can add, be effectively improved Growing Chicken growth retardation and weight gain slows down, reduce chicken group's Restoration stage The death rate and superseded number effectively release laying hen because the egg production caused by worm declines and inferior health syndrome, production performance of taping the latent power mention The Chinese herbal feed additive of high culture efficiency.
Illustrate Chinese herbal feed additive to the therapeutic effect of chicken rhinitis and protozoosis below by specific case.
It chooses that 2000 ages in days are 21, body condition, the good Sanhuang chicken of health status etc. are randomly divided into two groups, guarantees Every 1000 chickens composition is completely the same, and 2~4kg by the invention/ton material addition is fed since chicken 21 days (by Chinese medicine fodder Additive is sprayed on feed and stirs evenly), it is used in conjunction 5~7 days, effectively prevents chicken rhinitis and protozoosis, while setting up control Group the results are shown in Table 1:
Table 1:
Index subjet Quantity (only) Disease incidence (%) Weight
Control group 1000 15.5 265
Test group 1000 1% 290
Experiments have shown that, the Chinese herbal feed additive of the present embodiment can reduce disease incidence, and rapid growth weight by above-mentioned.
The good Sanhuang chicken laying hen of selection 2000, body condition, health status etc. is randomly divided into two groups, guarantees every 1000 Chicken composition is completely the same, in the addition of laying period, is used in conjunction 5~7 days, adds and (adds Chinese medicine fodder by 2~4kg/ton material Agent is sprayed on feed and stirs evenly), while control group is set up, it the results are shown in Table 2:
Table 2:
Index subjet Quantity (only) Disease incidence (%) Laying rate (%)
Control group 1000 10% 81.5
Test group 1000 0 94.5
Experiments have shown that, the Chinese herbal feed additive of the present embodiment can reduce disease incidence, and improve laying rate by above-mentioned.
The present invention is exemplarily described above, it is clear that the present invention is specifically designed and is not subject to the restrictions described above, As long as use the improvement for the various unsubstantialities that conception and technical scheme of the invention carry out, or it is not improved will be of the invention Conception and technical scheme directly apply to other occasions, within the scope of the present invention.

Claims (3)

1. the Chinese herbal feed additive of a kind of prevention and treatment chicken rhinitis and protozoosis, it is characterised in that by raw material Chinese medicine according to following weight Portion rate mixes: cloves 7~10, rhizoma zingiberis 7~10, Chinese torreyanut 10~15, Lappula echinata 10~15, stone-like omphalia 8~10, and dandelion 15~ 18, betel nut 5~8, cordate houttuynia 10~12, hairyvein agrimony 10~12, Radix Astragali 35~40.
2. the Chinese herbal feed additive of prevention and treatment chicken rhinitis according to claim 1 and protozoosis, it is characterised in that by raw material Chinese medicine is mixed according to following portions by weight ratio: cloves 10, rhizoma zingiberis 10, Chinese torreyanut 15, Lappula echinata 15, stone-like omphalia 10, dandelion 18, Bin Bulky 8, cordate houttuynia 12, hairyvein agrimony 12, Radix Astragali 40.
3. the preparation method of the Chinese herbal feed additive of prevention and treatment chicken rhinitis according to claim 1 and protozoosis, feature It is to include the following steps:
A, various raw material Chinese medicines are also known as taken into predetermined weight number;
B, it takes cloves, rhizoma zingiberis, betel nut, cordate houttuynia to mix and is distilled, obtain volatile oil and the dregs of a decoction;
C, the above-mentioned dregs of a decoction are mixed with Chinese torreyanut, Lappula echinata, stone-like omphalia, dandelion, hairyvein agrimony and adds water to cook secondary, will decocted twice To medical fluid mixing, concentration, stand after obtain mixing supernatant;
D, Radix Astragali is added water to cook three times, the medical fluid decocted three times is mixed, be concentrated, obtains Radix Astragali supernatant after standing;
E, oil, mixing supernatant and Radix Astragali supernatant be will volatilize and be mixed to get the Chinese herbal feed additive.
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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104222525A (en) * 2014-09-29 2014-12-24 青岛田瑞生态科技有限公司 Breeding method for reducing morbidity of laying hen whitecomb
CN105709081A (en) * 2014-12-02 2016-06-29 北京大北农动物保健科技有限责任公司 Pharmaceutical composition used for treating infectious rhinitis of chicken, applications thereof, and feed
CN107362337A (en) * 2017-06-28 2017-11-21 禹州市合同泰药业有限公司 One breeder Chinese medicine composition of enteron aisle expelling parasite and preparation method thereof
CN108392563A (en) * 2018-04-20 2018-08-14 佛山迁宇科技有限公司 A kind of feed addictive of prevention infectious coryza of chicken
CN109481591A (en) * 2018-12-27 2019-03-19 鼎正动物药业(天津)有限公司 The Chinese medicine composition and preparation method thereof for treating curing gallinaceous leucocyto zoonosis

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104222525A (en) * 2014-09-29 2014-12-24 青岛田瑞生态科技有限公司 Breeding method for reducing morbidity of laying hen whitecomb
CN105709081A (en) * 2014-12-02 2016-06-29 北京大北农动物保健科技有限责任公司 Pharmaceutical composition used for treating infectious rhinitis of chicken, applications thereof, and feed
CN107362337A (en) * 2017-06-28 2017-11-21 禹州市合同泰药业有限公司 One breeder Chinese medicine composition of enteron aisle expelling parasite and preparation method thereof
CN108392563A (en) * 2018-04-20 2018-08-14 佛山迁宇科技有限公司 A kind of feed addictive of prevention infectious coryza of chicken
CN109481591A (en) * 2018-12-27 2019-03-19 鼎正动物药业(天津)有限公司 The Chinese medicine composition and preparation method thereof for treating curing gallinaceous leucocyto zoonosis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
于匆: "《最新实用兽医手册》", 31 August 1999, 中国农业科技出版社 *
养殖宝平台: "《中兽药处方大全》", 20 June 2019 *

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