CN110384766A - A kind of Se-enriched herbal medicine composition improving spermatoblast vigor - Google Patents
A kind of Se-enriched herbal medicine composition improving spermatoblast vigor Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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Abstract
The invention discloses a kind of Se-enriched herbal medicine compositions for improving spermatoblast vigor, belong to field of Chinese herbal medicine technology.It counts composed of the following components in mass ratio: 30-50 parts of organic Se-rich yam flour, 5-20 parts of organic Se-rich wolfberry fruit powder, 0.2-2.0 parts of dendrobium officinale powder, 10-30 parts of kudzu-vine root powder, 2-10 parts of Poria cocos powder, 5-20 parts of brown sugar.Wherein organic Se-rich yam flour is iron rod yam powder, and Se content reaches 1.5-6ppm, and organic Se-rich wolfberry fruit powder is lycium barbarum powder, and Se content reaches 3-15ppm, and dendrobium officinale powder, kudzu-vine root powder, Poria cocos powder originate from Da Bie Mountain area.The Se content of final gained herbal composite is 2.0-6.0ppm.The present invention can greatly increase the quantity of sperm, improve the quality and vigor of sperm, reduce rate of teratosperm, have no toxic side effect, have no adverse reaction, do not stimulate digestion, and can obtain the effect for improving male sterility well.
Description
Technical field
The invention belongs to field of Chinese herbal medicine technology, and in particular to a kind of Se-enriched herbal medicine combination for improving spermatoblast vigor
Object.
Background technique
Healthy reproduction is to constitute the important foundation stone of human individual's health, even more everyone fundamental right.And current, China
The status of male reproductive health equally allows of no optimist, and is faced with that male sterility, prostatic disorders, reproductive tract infection etc. are many to ask
Topic, the public and society also need to be further increased to the cognition degree and participation of male reproductive health.Male sterility is that male is raw
Grow healthy focus in recent years, China male sterility patient is in the trend increased year by year.The sperm average counter of human seminal fluid
41.5% is had dropped in halfth century.In recent years the disease incidence of American-European countries's sterility is also up to 15%, i.e., in every seven couples of Mr. and Mrs just about
There is a pair of of infertility person, cause of disease men and women is fifty-fifty.China only sporadicly reports on the ground such as Beijing, Henan that male sterility disease incidence is just at present
Up to 2-5%.Lead to the factor of male sterility, including Sperm specific enzyme and maturation exception, semen quality problem, AsAb
Equal immune factors, pathogenic infection etc., and indicate that the index of male fecundity most critical is under sperm quality in outpatients
Drop, causes fecundity to decline.Male sterility problem becomes the focal issue of male reproductive health at present and China compels to be essential
The important healthy reproduction problem of to be paid close attention to one.
Selenium is essential for the fecundity of man.The biosynthesis of stosterone needs selenium, the formation of sperm
Selenium is also required to development.There is the exception of structure in the sperm body portion of the animal of selenium deficiency diet, and the mobility of sperm is poor,
Tail portion has the tendency that fracture.The U.S. (science) magazine was once published research report and claimed: the amount that selenium is taken in diet is male less
One of the reason of infertility, because selenium can effectively prevent, the protein in sperm is not oxidized, greatly improves the survival rate of sperm,
Improve the vigor of sperm.
Selenium organizes in body fluid content successively in male are as follows: kidney, liver, testis, cardiac muscle, intestines, lung, brain, muscle.In males
Selenium, there is 25%-40% to concentrate on reproductive system, selenium has effects that enhance sperm motility and sexual performance.To there is different degrees of property
For the male of deterioration, the adjustable immune function of selenium-supply and anti-oxidation function, selenium can improve and improve sexual function, help
There is the people of impotence, premature ejaculation, sexual disorder gradually back to normal.Selenium can enhance the vigor of mankind spermatozoon simultaneously, before promoting sperm
The penetration power of calcium acrosome is held, increases pregnancy chance, reaches prenatal and postnatal care.
Selenium is divided into inorganic selenium, organic selenium, vegetable active selenium.Inorganic selenium belongs to industrial selenium, is to be prohibited (to use by the world
In edible and medical treatment).Inorganic selenium is very big to human injury, and inorganic selenium has biggish toxicity, and is not easy to be absorbed, and is not suitable for people
It is used with animal.There is (such as yeast selenium) generally in the form of selenomethionine in organic selenium, Methionine metabolism approach is followed to be metabolized, ginseng
With the synthesis of albumen, stores, absorbs within the organization；It is absorbed by the body and is immediately used by the body, be effectively improved blood selenium situation in human body.But
The absorptivity of organic selenium is incomplete, and it is internal to be not easy discharge.Present some selenium-supply food are all organic selenium mostly.Vegetable active
Selenium refers to that crops absorb selenium element from the soil improved by technique of enriched selenium, turns through photosynthesis and crops vivo biodistribution
Change effect, exists in the form of seleno-amino acids in crops body.
Summary of the invention
It is an object of the invention to be gradually risen for male sterility disease incidence described above, the quantity of mankind spermatozoon and
The case where there is the trend being decreased obviously in quality, and male reproductive health is just seriously threatened, provide one kind have no toxic side effect,
It has no adverse reaction, and the quality and vigor, the organic Se-rich herbal composite for reducing rate of teratosperm of sperm can be improved.
A kind of Se-enriched herbal medicine composition improving spermatoblast vigor, counts composed of the following components in mass ratio: having
30-50 parts of machine selenium-rich Chinese yam powder, 5-20 parts of organic Se-rich wolfberry fruit powder, 0.2-2.0 parts of dendrobium officinale powder, 10-30 parts of kudzu-vine root powder, Fu
2-10 parts of Siberian cocklebur powder, 5-20 parts of brown sugar.
As preferred case, the organic Se-rich yam flour is iron rod yam powder, and Se content reaches 1.5-6ppm, contained by selenium
The organic Se-rich Chinese yam processing that amount is 0.5-2ppm is made, and the excrement that 30 jin of piggys below are applied within Chinese yam growth period is made
Standby selenium-rich farmyard manure, the albumen selenium (in terms of selenium) in the feed of piggy containing 0.5-1.0ppm, is first used before planting Chinese yam
Selenium-rich pig manure after fermentation improves soil, then respectively applies 1 selenium-rich pig manure farmyard manure 100- in Chinese yam Seedling Stage and growth period
150kg/ mus, water-solubility protein selenium aqueous solution (organic selenium content 0.02 ‰) is used pouring root 2 times in Chinese yam tuber expansion period, twice
Interval 30 days.
As preferred case, the organic Se-rich wolfberry fruit powder is lycium barbarum powder, and Se content reaches 3-15ppm, contained by selenium
The organic Se-rich fructus lycii processing of amount up to 1-5ppm are made, prepared by the excrement that half free-ranging selenium enriched chicken is applied within fructus lycii growth period
Farmyard manure, the albumen selenium (in terms of selenium) containing 0.5-1.0ppm in the feed of selenium enriched chicken, in fructus lycii germination period, florescence and bears fruit
Phase, respectively to 100-150kg/ mus of selenium-rich chicken manure farmyard manure after the application fermentation of its root, after bearing fruit, water of foliage-spray
Dissolubility albumen selenium aqueous solution (organic selenium content 0.02 ‰).
As preferred case, the dendrobium officinale powder is huoshan dendrobium candidum powder, by originating from Da Bie Mountain area --- Anhui
Cleaned-low temperature drying -200 mesh of ultramicro grinding-mistake of the huoshan dendrobium candidum of Huoshan County, province, the dendrobium candidum being prepared are super
Fine powder.
As preferred case, the kudzu-vine root powder by the wild bavin Pueraria lobota for originating from Da Bie Mountain area it is cleaned-crush defibrination-
Screenings separation-sedimentation starch-drying-crushing is prepared.
As preferred case, the Poria cocos powder raw material is the Yuexi Poria cocos for originating from Da Bie Mountain area, through sweating, brewed, profit
It makes, steam, being sliced, drying, crushing and be prepared.
As preferred case, the Se content of the herbal composite is 2.0-6.0ppm.
As preferred case, the Chinese herbal medicine group, which is combined into, can be made into tablet, pill, decoction or powder.
The beneficial effects of the present invention are: selenium is one of indispensable microelement in animal body, as glutathione
The important composition ingredient of catalase (GSH-Px) can eliminate the free radical of body generation, and sperm is extremely sensitive to free radical,
Selenium deficiency will lead to sperm motility decline, mitochondria development and paramophia；Herbal composite in the present invention can tonify the liver and kidney,
Establishing-Yang controlling nocturnal emission with astringent drugs, having improves sexual function, and strengthen immunity increases semen quality and other effects, and clinical effectiveness is significant, shortens male
The infertility treatment course for the treatment of alleviates the financial burden of male sterility patient.
Selenium in the present invention is vegetable active selenium, and selenium is absorbed into vivo from the soil of selenium-rich element, passes through by crops
The entire growth course of crops, by the biotransformation of photosynthesis and crops itself, by minerals and organic shape
The selenium element of state is converted to the selenomethionine etc. for being easily absorbed by the human body and being metabolized.That is vegetable active selenium is to be easier to human body suction
It receives.The vegetable active selenium rate of being absorbed by the body is up to 99% or more, while also solving the problems, such as that metabolic rate is low, vegetable active selenium
Pass through body metabolism channel such as in conjunction with human body heavy metal and toxic organics, and by harmful substance: sweat, breathing, row
It lets out etc. and to excrete, to play a protective role to human health.
Specific embodiment
In order to be easy to understand the technical means, the creative features, the aims and the efficiencies achieved by the present invention, tie below
Specific embodiment is closed, the present invention is further explained.
Embodiment powder of the invention
Organic Se-rich yam flour 1000g, organic Se-rich wolfberry fruit powder 160g, kudzu-vine root powder 330g, Poria cocos powder 150g, iron sheet stone are taken respectively
Dry measure used in former times powder 60g, brown sugar 300g are uniformly mixed, are distributed into 100 bags and powder of the present invention is made.
Application method: boiled water is taken after mixing it with water, and daily 1 dose, is continuously taken 20-30 days.For improving mankind spermatozoon cell viability one
As 10 days work, can obviously improve within 20-30 days.
Typical case:
Guizhou patient Pei, the age 35 years old, wife week certain, 30 years old, educate female 3.5 years old, secondary standby pregnant, wife is once in 2018 years 10
The moon becomes pregnant, miscarriage in November.On inspection, the wife's side is normal, bridegroom's or husband's side Sperm recovery: (PR+NR) sperm total activity 40%, before PR to
Motile rate 27%, semen analysis result is similar for several times before.Diagnosis: it is undesirable to belong to long-term sperm motility.Take the present invention
20 doses of Chinese herbal medicine powder after, conventional semen efamination: (PR+NR) sperm total activity 73.6% is carried out again, as motile before PR
Rate 64.2%.
Kunming patient poplar, the age 40 years old, patient got married the several years, unfertilized always, and sperm motility only has 5% on inspection, essence
Sub- every milliliter of density 40,000,000.Diagnosis: belong to azoospermia.After taking 15 doses of Chinese herbal medicine powder of the invention, carry out again conventional
Semen efamination: sperm motility is up to 63%, every milliliter of sperm concentration 45,000,000.Its wife of next year is pregnant and gives birth to a girl baby.
Shanghai patient Lee, male, 34 years old, 6 years after marriage unfertilized, and sexual life is normal, and on inspection, spouse is normal, Semen routione
It checks: 2.5 milliliters of semen volume, not liquefying within 1 hour, 1 hour living spermatozoa percentage 25% of sperm drainage, diagnosis: disease of not liquefied sperm, weak essence
Disease.It takes Chinese herbal medicine powder of the invention, after 30 doses, carries out conventional semen efamination again: 3 milliliters of semen volume, liquefying time 40
Minute, living spermatozoa percentage continues after taking 20 doses of Chinese herbal medicine powder of the present invention up to 75%, its wife of next year is pregnant and gives birth to a male
Baby.
Shandong patient Liu, male 38 years old, wife Mr. Wang 35 years old educates female 10 years old, intends having two babies from patient 2016 having no resolution,
Wife is normal on inspection, and Liu treats drinking too much, severe fatty liver, high blood pressure, accidental premature ejaculation disease with courtesy because usually operating pressure is big
Shape, while suffering from aspermia or oligospermia.Using rouge calming the liver drug of dispelling, and cooperate and take 14 doses of Chinese herbal medicine powder of the invention, examines after two weeks
It looks into fatty liver condition and vascular hypertension is mitigated, sperm motility increases, its wife of Liu's incoming all announcement has cherished after 2 months
Pregnant, next year gives birth to a boy baby.
Beijing patient week certain, the age 35 years old, wife Liu, the age 32 years old, 2 years after marriage without pregnant.On inspection, patient's sperm
Hypoplasia, for rate of teratosperm 80% or more, wife is healthy.Chinese medicine is moved on under western medical treatment is invalid, takes Chinese herbal medicine of the present invention
After 14 doses of powder, 2 months, wife's pregnancy.
Finally, it should be noted that the above description is only a preferred embodiment of the present invention, it is not intended to restrict the invention, although
The present invention will be described in detail with reference to the foregoing embodiments, for those skilled in the art, still can be to preceding
Technical solution documented by each embodiment is stated to modify or equivalent replacement of some of the technical features, it is all at this
Within the spirit and principle of invention, any modification, equivalent replacement, improvement and so on should be included in protection model of the invention
Within enclosing.
Claims (8)
1. a kind of Se-enriched herbal medicine composition for improving spermatoblast vigor, it is characterised in that: it is counted by with the following group in mass ratio
It is grouped as: 30-50 parts of organic Se-rich yam flour, 5-20 parts of organic Se-rich wolfberry fruit powder, 0.2-2.0 parts of dendrobium officinale powder, kudzu-vine root powder
10-30 parts, 2-10 parts of Poria cocos powder, 5-20 parts of brown sugar.
2. a kind of Se-enriched herbal medicine composition for improving spermatoblast vigor according to claim 1, it is characterised in that: institute
The organic Se-rich yam flour stated is iron rod yam powder, and Se content reaches 1.5-6ppm, the organic Se-rich for being 0.5-2ppm by Se content
Chinese yam processing is made, and selenium-rich farmyard manure prepared by the excrement of 30 jin of piggys below is applied within Chinese yam growth period, in piggy
Feed in the albumen selenium (in terms of selenium) containing 0.5-1.0ppm, before planting Chinese yam first with fermentation after selenium-rich pig manure conditioned soil
Then earth is respectively applied 1 100-150kg/ mus of selenium-rich pig manure farmyard manure in Chinese yam Seedling Stage and growth period, is expanded in Chinese yam stem tuber
Phase uses water-solubility protein selenium aqueous solution (organic selenium content 0.02 ‰) pouring root 2 times, two minor ticks 30 days.
3. a kind of Se-enriched herbal medicine composition for improving spermatoblast vigor according to claim 1, it is characterised in that: institute
The organic Se-rich wolfberry fruit powder stated is lycium barbarum powder, and Se content reaches 3-15ppm, and the organic Se-rich fructus lycii of 1-5ppm is reached by Se content
Processing is made, and farmyard manure prepared by the excrement of half free-ranging selenium enriched chicken is applied within fructus lycii growth period, is contained in the feed of selenium enriched chicken
There is the albumen selenium (in terms of selenium) of 0.5-1.0ppm, in fructus lycii germination period, florescence and the phase of bearing fruit, its root is applied ferment respectively
100-150kg/ mus of selenium-rich chicken manure farmyard manure afterwards, after bearing fruit, water-solubility protein selenium aqueous solution (organic selenium of foliage-spray
Content 0.02 is ‰).
4. a kind of Se-enriched herbal medicine composition for improving spermatoblast vigor according to claim 1, it is characterised in that: institute
The dendrobium officinale powder stated is huoshan dendrobium candidum powder, by originating from Da Bie Mountain area --- the huoshan dendrobium candidum of Huoshan County, Anhui Province passes through
Cleaning-low temperature drying -200 mesh of ultramicro grinding-mistake, the dendrobium candidum ultrafine powder being prepared.
5. a kind of Se-enriched herbal medicine composition for improving spermatoblast vigor according to claim 1, it is characterised in that: institute
The kudzu-vine root powder stated by the wild bavin Pueraria lobota for originating from Da Bie Mountain area it is cleaned-crush defibrination-screenings separation-sedimentation starch-drying-
Crushing is prepared.
6. a kind of Se-enriched herbal medicine composition for improving spermatoblast vigor according to claim 1, it is characterised in that: institute
The Poria cocos powder raw material stated is the Yuexi Poria cocos for originating from Da Bie Mountain area, makes through sweating, brewed, profit, steams, is sliced, dries, crushes system
It is standby and obtain.
7. a kind of Se-enriched herbal medicine composition for improving spermatoblast vigor according to claim 1, it is characterised in that: institute
The Se content for the herbal composite stated is 2.0-6.0ppm.
8. a kind of Se-enriched herbal medicine composition for improving spermatoblast vigor according to claim 1, it is characterised in that: institute
The Chinese herbal medicine group stated, which is combined into, can be made into tablet, pill, decoction or powder.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116211948A (en) * | 2023-02-21 | 2023-06-06 | 上海奥格营养生物科技有限公司 | Traditional Chinese medicine composition for improving sperm quality and mixing equipment thereof |
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|---|---|---|---|---|
| CN104069315A (en) * | 2014-06-29 | 2014-10-01 | 苟晓龙 | Sperm production formula for treating male infertility |
| CN104758715A (en) * | 2014-09-03 | 2015-07-08 | 江苏颐海药业有限责任公司 | Traditional Chinese medicine for treating male infertility |
| CN105233001A (en) * | 2015-10-29 | 2016-01-13 | 山东省计划生育科学技术研究所 | Traditional Chinese medicine for treating male sexual dysfunction and infertility and preparation method of traditional Chinese medicine |
| CN109453306A (en) * | 2018-12-27 | 2019-03-12 | 同溢堂药业有限公司 | A kind of drug and preparation method thereof for treating male sterility |
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2019
- 2019-08-05 CN CN201910715922.3A patent/CN110384766A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104069315A (en) * | 2014-06-29 | 2014-10-01 | 苟晓龙 | Sperm production formula for treating male infertility |
| CN104758715A (en) * | 2014-09-03 | 2015-07-08 | 江苏颐海药业有限责任公司 | Traditional Chinese medicine for treating male infertility |
| CN105233001A (en) * | 2015-10-29 | 2016-01-13 | 山东省计划生育科学技术研究所 | Traditional Chinese medicine for treating male sexual dysfunction and infertility and preparation method of traditional Chinese medicine |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116211948A (en) * | 2023-02-21 | 2023-06-06 | 上海奥格营养生物科技有限公司 | Traditional Chinese medicine composition for improving sperm quality and mixing equipment thereof |
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Application publication date: 20191029 |
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