CN110327433A - It is a kind of so that canthus is raised up, the liquid preparation that eye loosens - Google Patents
It is a kind of so that canthus is raised up, the liquid preparation that eye loosens Download PDFInfo
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Abstract
The present invention relates to technical field of traditional Chinese medicine preparation, and in particular to it is a kind of so that canthus is raised up, the liquid preparation that eye loosens.Liquid preparation of the invention, by Chinese medicine Radix Notoginseng, Selaginella tamariscina, radix tetrastigme and corn stigma 60-70%(v/v) ethyl alcohol immersion, each constituents in medicinal material are extracted, obtain liquid preparation after then removing ethyl alcohol therein by revolving volatilization.The preparation process of liquid preparation of the invention is easy, can high-volume large-scale production.Liquid preparation prepared by the present invention, energy activating microcirculation and removing stasis medicinal, clearing and activating the channels and collaterals can effectively improve local microcirculation obstacle caused by excess eye-using, reduce skin temperature, it is nervous to alleviate eye muscle, restores elasticity, accelerates the metabolism of eye capillary, promote ocular circulation, alleviate eye strain, eye nutrition is supplemented, to take good care of eye health comprehensively.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, and in particular to it is a kind of so that canthus is raised up, the liquid preparation that eye loosens.
Background technique
The national health health committee, the Ministry of Education, General Administration of Sport, which combine, to have printed and distributed " about the development whole nation in 2018
" Eye-care Day " movable notice ".Should " notice " require that health at different levels, education, that sports departments further recognize children and youth is close
It is common to promote the work of children and youth sight protectio depending on the importance of prevention and control.
It is reported that the continuous 3 years themes by " Eye-care Day " of country focused on children and youth myopia prevention and control from 2016.
June 6 this year is the 23rd whole nation " Eye-care Day ", and active theme is " science bridle myopia, love child's eye health ".
In recent years, the myopia problem of children and youth is got worse and low age trend is obvious, it has also become great society is public
Hygienic issues.According to incompletely statistics, pupil's disease incidence about 30% in junior middle school possible 60%, arrives senior middle school about 80%, university is about
90%.Although also lacking a country-wide survey data at present, overall incidence presentation morbidity is early, progress is fast, degree
High trend.
The eyes are the windows of the mind, and modern is generally near-sighted, and modern electronic equipment is polynary, and portable computer is with modern
Daily 8-12 hour, since work and study pressure is big, continuously eye fatigue, myopia caused by eye of staying up late is that puzzlement is modern
How the problem of people alleviates eye pressure, loosens eyes, is a big proposition.
As excess eye-using, stay up late, black eye, eye pouch caused by daily life is bad etc. the problems such as, and with the increasing at age
The problem of the problems such as relaxation of eye caused by big is sagging, microgroove, crow's feet and people seeking beauty extremely take notice of.
Loosen the product of eye for alleviating eye strain on the market now, three categories can be attributed to.The first kind is medicament for the eyes
The effect of water class, alleviates the sensation of dryness of eyes by way of instillation, existing product be not significant；Second class is eye essence
Patch, by applying now, in terms of more beauty partially, and effect is limited；Third class is instrument class, passes through the sides such as infrared, heating
Formula improves eye strain, and limitation is inconvenient to carry.Existing Chinese medicine eye-care class product is usually to solve black eye
The problems such as circle, eye pouch, alleviation microgroove, skin care, without solving canthus sagging problem.It is eye fatigue that canthus is sagging, is declined
Old sign.
Summary of the invention
For the deficiencies in the prior art, the first purpose of this invention be to provide it is a kind of canthus can be made to raise up,
The liquid preparation that eye muscle loosens and promotes blood circulation loosens eye muscle by being applied with or be applied to eye circumference skin,
Blood circulation system is smooth, and eye strain is made to be eased, and external be mainly manifested in raises up in canthus, while making eye black eye
Thin out, eye pouch mitigates, microgroove shoals, white of the eye de-etiolation highlights.
Second object of the present invention is to provide the preparation method of aforesaid liquid preparation.
Inventive concept of the invention is as follows:
Eye fatigue can be divided into modulability eye fatigue, flesh eye fatigue and nerve eye fatigue.In addition to nerve
Outside eye fatigue, the state of an illness of the former two may cause myopia, astigmatism or the different presbyopia of right and left eyes degree etc..Crystalline lens week
It is with one layer of ciliary muscle, ciliary body suspensorium, eye strain can enable ciliary spasm, boundary, follow the string, and make lenticular curvature
Increase, causes adjusting inaccuracy, adjustment speed slow, that is, pseudo-myopia phenomenon occur.If chronic fatigue, muscle loses bullet
Property, when will compress eyeball generation horizontal axis deformation (eyeball variation ellipse shape), occur as soon as true myopia.Pseudo-myopia is restorative
It is relatively good, it can cure.True myopia, available part are restored, and few people restore completely.And each A nearsighted person is more
It less while including false and true myopia, therefore, false part is treated, and true property part cannot restore completely；Also it just explains
Why most of myopia can only restore eyesight to 1.2-1.3, and few people can be restored to the basic reason of 1.5 eyesights.
The entire densely covered capillary microcirculation of eye, provides energy and metabolism waste liquid for eye, when excessive eye use, blood
When the energy supply deficiency of liquid circulation, needed for eye circulating system priority of supply eyeball, so as to cause black eye and eye pouch, after
Eyeball congestion is resulted in again.Eye energy supply deficiency will lead to asthenopia, at the moment feel ophthalmic uncomfortable, eyeball or its around
Pain, nasion portion or temples acid is swollen, blurred vision, eye are dry, has constriction and burning heat sensation, keep in dark place, diplopia and shed tears etc. is felt,
When feeling eye fatigue, actually eye muscle has been seriously to overwork, and blood circulation system severely exceeds.
In conclusion improve eye problems is two o'clock at all: first, the eye muscle of relaxation of tension, eye muscle
Loosen, restore elasticity, no longer compressing involves augen, and eye is fundamentally loosened, and is relieved fatigue.The microgroove of eye and fish
Tail line is fundamentally product after eye muscle relaxation is sagging, squeezes and occurs when being periocular muscle and facial muscles facial expressions and acts
Characterization, therefore, eye muscle of loosening, it is possible to find eye raises up state from sagging recovery, reduces the extruding with facial muscles, from
And the problems such as improving crow's feet, microgroove；Second, improve ocular circulation and metabolic system, promotes eye QI-blood circulation, eye
Energy supply is kept up with, eye is congested, it is dry and astringent etc. energize insufficient problem and be eased, while the dysbolisms problem such as black eye, eye pouch obtains
To alleviate.
In order to realize the first purpose of this invention, present invention employs following technical measures:
It is a kind of so that canthus is raised up, the liquid preparation that eye loosens, by Chinese medicine Radix Notoginseng, Selaginella tamariscina, radix tetrastigme and corn stigma use
60-70% (v/v) ethyl alcohol impregnates, and extracts each constituents in medicinal material, after then removing ethyl alcohol therein by revolving volatilization
Obtain liquid preparation.
Further, the Radix Notoginseng be fresh Panax notoginseng root cleaned, dried, smashed powder；
Further, the Selaginella tamariscina be fresh Selaginella tamariscina herb cleaned, dried, smashed powder；
Further, the radix tetrastigme be fresh radix tetrastigme root cleaned, dried, smashed powder；
Further, the corn stigma is gained after fresh corn silk is cleaned, dried.
Further, the Chinese medicine Radix Notoginseng, Selaginella tamariscina, radix tetrastigme, corn stigma weight are as follows:
Preferred proportion are as follows:
Optimal proportion are as follows:
In order to realize second purpose, present invention employs following technical measures:
A kind of parts by weight of raw materials proportion it is as above so that canthus is raised up, the preparation method for the liquid preparation that eye loosens, step
It is rapid as follows:
(1) it takes Radix Notoginseng, Selaginella tamariscina, radix tetrastigme and corn stigma to be placed in container, 60-70% (v/v) ethyl alcohol is added, impregnate no mistake
Chinese drugs powder 10-30cm impregnates 3-6 months；
(2) filtrate is obtained by filtration；
(3) add 60-70% (v/v) ethyl alcohol into filtering gained sediment, impregnate and do not cross sediment 5-10cm, impregnate 1-3
A month；
(4) filtrate is obtained by filtration；
(5) filtrate obtained by step (2) and (4) is merged, device is rotated by vacuum decompression, is arranged 50-70 revs/min of revolving speed
Clock, distills out ethyl alcohol and volatile substances therein (under this condition, with the growth of time, second by 50-60 DEG C of bath temperature
The volatile substances such as alcohol gradually volatilize, until volatilization completely, there is no until condensate liquid) obtain the extract of primary aqueous, i.e.,
For it is of the invention so that canthus is raised up, the liquid preparation that eye loosens.
Further, described so that canthus is raised up, liquid preparation color that eye loosens is yellow, sticky and easy wire drawing liquid
Shape, main component are water, amino acid, mucin and polysaccharide etc..
The principles of formulating prescriptions of each traditional Chinese medicinal material raw materials of the present invention are as follows:
The effect of Radix Notoginseng: Compendium of Material Medica, which records Radix Notoginseng, hemostasis, scattered blood, analgesic therapy.Golden sword arrow wound, falls and flutters cane sore, blood goes out
More than person chews rotten painting, or mixes it for end, and blood is i.e. only.Also main haematemesis, bleeding from five sense organs or subcutaneous tissue, lower blood, bloody flux, metrorrhagia, incessant menorrhea, postpartum
Extravesated blood not under, blood fortune, blood pain, Akamu, carbuncle swells, tiger stings, all diseases of snakebite.Promote blood cell new old generation modern research shows that having
It thanks, the function of balance adjustment blood cell.
Selaginella tamariscina: it is recorded in " book on Chinese herbal medicine is looked for the truth ": Selaginella tamariscina, slightly cold, power energy blood-breaking promoting menstruation, therefore control the diseases such as abdominal mass leaching knot.Herb has
Hemostasis, convergent efficiency.It is civil that its complete stool incinerates, it is for oral administration to treat various haemorrhages and rape oil mixes external application, it can control
Treat various wounds.Long term usage is made light of one's life by commiting suicide and color (Shennong's Herbal).
Radix tetrastigme: also known as gold thread hoist, hemsley rockvine root, soil, through ball, herb can be used as medicine, with underground root tuber medicinal effects
Preferably, there is clearing heat and detoxicating, blood circulation promoting and dispersing pathogen accumulation, anti-inflammatory analgetic, dispelling pathogenic wind and eliminating phlegm, regulating qi-flowing for strengthening spleen and other effects.
Corn stigma: corn stigma, Chinese medicine name.For the style and column cap of gramineae plant maize Zea mays L., there is diuresis
The effect of detumescence, clear liver and gallbladder." civil common glossary of Herbs and Drugs ": corn stigma can reduce blood pressure, inducing diuresis to remove edema.It controls nosebleed, red collapse.
" Traditional Chinese Medicine in Sichuan will ": removing heat from blood, diuresis.Yellow River harnessing subcutaneous ulcer, wind-heat, eruption are spitted blood and red are collapsed.
It is different from most of drug matchings, tens kinds of even hundreds of Chinese medicines are piled up, and the present invention only simplifies four kinds of medicinal materials, and four
Kind of medicinal material belongs to medicinal herbs most in use, and also one of which is used for the solution of eye problems by someone, and the present invention program is by these four medicines
After material combination, sticky wire drawing can be obtained, is rich in amino acid, and be easy to absorbed liquid preparation.Chinese medicine is particular about compatibility, compatibility
Monarch is particular about, and the assurance of the amount to medicinal material, core of the present invention are Radix Notoginseng, Selaginella tamariscina, radix tetrastigme, corn creatively
Four kinds of compatibility of drugs of palpus, Radix Notoginseng is monarch drug in a prescription, leading promoting blood circulation to remove blood stasis；Radix tetrastigme is ministerial drug, leading removing heat from blood, drives blood poison；Selaginella tamariscina is
Adjutant, blood-breaking promoting menstruation；Corn stigma is to make medicine, clear liver and gallbladder.This is thousands of kinds of Chinese medicine former material obtained by experience and intention inspiration,
Compatibility is proper just to obtain prescription significant in efficacy.
Compared with prior art, the present invention has the following advantages and beneficial effects:
The present invention is studied by a large amount of theory and practice, creatively proposes that a kind of pure Chinese medicine composition is extracted to be obtained
So that canthus is raised up, the liquid preparation that eye loosens, the liquid preparation have activating microcirculation and removing stasis medicinal, promote blood circulation, loosen eye
Muscle can provide energy for eye, so that the bright eye of improving eyesight, eliminates black eye, eye pouch, loosen eye.Liquid prepared by the present invention
Preparation, energy activating microcirculation and removing stasis medicinal, clearing and activating the channels and collaterals can effectively improve local microcirculation obstacle caused by excess eye-using, reduce skin temperature,
It is nervous to alleviate eye muscle, restores elasticity, accelerates the metabolism of eye capillary, promotes ocular circulation, alleviates eye
Portion's fatigue, supplements eye nutrition, to take good care of eye health comprehensively.
The preparation process of liquid preparation of the invention is easy, smashes-impregnating twice-and filters merging filtrate-revolving, can all make
With instrument and equipment, streamlined mechanization.All raw materials have all realized cultivation, and cost is controllable, can high-volume large-scale production.
Detailed description of the invention
Fig. 1 is human eye section internal anatomy.
Fig. 2 is mankind's asthenopia crux analysis figure.
Fig. 3 is effect picture of the case one using the liquid preparation of the embodiment of the present invention 1.
Fig. 4 is effect picture of the case two using the liquid preparation of the embodiment of the present invention 1.
Fig. 5 is effect picture of the case three using the liquid preparation of the embodiment of the present invention 1.
Fig. 6 is effect picture of the case four using the liquid preparation of the embodiment of the present invention 1.
Fig. 7 is effect picture of the case five using the liquid preparation of the embodiment of the present invention 1.
Fig. 8 is effect picture of the case six using the liquid preparation of the embodiment of the present invention 1.
Fig. 9 is effect picture of the case seven using the liquid preparation of the embodiment of the present invention 1.
Figure 10 is effect picture of the case nine using the liquid preparation of the embodiment of the present invention 1.
Figure 11 is effect picture of the case ten using the liquid preparation of the embodiment of the present invention 2.
Figure 12 is effect picture of the case 11 using the liquid preparation of the embodiment of the present invention 2.
Figure 13 is effect picture of the case 12 using the liquid preparation of the embodiment of the present invention 3.
Figure 14 is effect picture of the case 13 using the liquid preparation of the embodiment of the present invention 3.
Specific embodiment
Applicant will in conjunction with specific embodiments be described in further detail application of the invention below.It should be understood that
The following contents should not in any way limit protection scope of the present invention.
Embodiment 1: it is a kind of so that canthus is raised up, the preparation method for the liquid preparation that eye loosens, its step are as follows:
It smashes: taking dry Roots of Panax Notoginseng, Selaginella tamariscina herb, radix tetrastigme root, crushed respectively by pulverizer, respectively obtain Radix Notoginseng
Powder, Spikemoss, radix tetrastigme powder, it is spare；
It impregnates: the dry corn stigma of 2000g Notoginseng Root, 200g Spikemoss, 1000g radix tetrastigme powder and 2000g is set
Do not had herb powder 30cm high in 60 degree of kaoliang spirits in 50L ceramic vessel, are added, impregnated 3 months.
Filtering: two layers of crocus cloth of medical fluid is filtered；
It impregnates again: 60 degree of kaoliang spirits being added into filter residue, do not had filter residue 10cm high, impregnate 1 month.
It refilters: two layers of crocus cloth of medical fluid is filtered；
Revolving: merging filtrate twice, rotates evaporimeter using vacuum, and 60 revs/min of revolving speed, 55 DEG C of bath temperature.At this
Under the conditions of, the volatile substances such as ethyl alcohol can preferential volatilization, water can also evaporate in right amount, condensation liquor collecting device after ten minutes there is no
Condensate liquid generates, and is considered as ethyl alcohol volatilization completely, is sterilized by ultraviolet light irradiation, obtain aqueous liquid preparation, is applied by practical eye
Observation, it is nonirritant.
By high performance liquid chromatography detection, it is rich in amino acid and microelement in this liquid preparation, wherein primary amino acid
Component, the concentration in Essence and content are shown in Table one, and main trace element, the concentration in liquid preparation and content are shown in Table
Two.
One primary amino acid component of table, concentration and content in liquid preparation
In 17 kinds of amino acid, the content of aspartic acid, glutamic acid and proline is higher, accounts for amino in liquid preparation respectively
18.09%, 23.24% and the 11.63% of sour total component.
Firstly, aspartic acid is small-molecule substance, molecular weight is less than 1000.Aspartic acid participates in ornithine circulation, promotes
Oxygen and carbon dioxide generates urea, reduces the amount of nitrogen and carbon dioxide in blood, enhances liver function, eliminates fatigue.It can enhancing
Liver function adjusts the metabolic function of brain and nerve, eliminates fatigue, plays good health-care effect to eye.Promote epithelial cell
The ability of differentiation.
Glutamic acid is one of the primary amino acid of nitrogen metabolism in living organism, is of great significance in metabolism.Liver pair
Obstacle is occurred by the link that ammonia is converted into urea, causes blood ammonia to increase, encephalopathy symptom occurs.The intake of glutamic acid advantageously reduces
And blood ammonia is eliminated, so as to improve Ocular indications.And blood vessel can be expanded, enhancing blood circulation effect is obvious.
Proline is one of component of phytoprotein, and can be widely present in plant with free state.In biology
In vivo, proline is not only ideal osmotic adjustment, and be alternatively arranged as film and enzyme Protective substances and free radical it is clear
Except agent, to play a protective role to growth of the plant under osmotic stress, for another is important in potassium ion organism
Accumulation of the osmotic adjustment in vacuole, proline can play the adjustment effect to cytoplasm osmotic equilibrium again.Dried meat
The connective tissue that propylhomoserin can promote tissue trauma position is grown up healthy and sound.
Two main trace element of table, concentration and content in liquid preparation
In 11 kinds of microelements, the content of zinc and copper is higher, accounts for microelement total amount in surveyed liquid preparation respectively
57.71% and 9.43%.
Zinc widely participates in the metabolism of nucleic acid and protein, the adjusting to the various enzymes and receptor that influence physiological brain function
There is important role, and cell fast breeding and differentiation can be promoted, to make healing wound fast.Zinc participates in liver and retina
The composition of retinol reductase in histocyte directly affects the metabolism of vitamin A and the effect of retinol.It is rod-shaped thin when zinc-deficiency
Born of the same parents synthesize rhodopsin obstacle, and dark adaptation is caused to weaken, and occur " sparrow is blind ", and cone cell synthesizes the influence of visual purple orchid obstacle and cone cell is thin
Born of the same parents distinguish color miopragia.Illustrate that zinc has special function in maintenance visual aspects.
Copper has a major impact the development of brain and central nervous system and function.Some researches show that high myopias
Serum copper, Zn content are significantly lower than normal person, and copper becomes apparent from than zinc reduction, shows that eyesight is related with copper zinc metabolic disorder.
Liquid preparation prepared by embodiment 1 is used for different study subjects:
Application method: taking liquid preparation drop in eye cotton pads, and infiltration is drenched, closes eyes, cotton pads is covered in
Eye is removed after 20min, is massaged into and fully absorbs, take pictures after 10min.
Case one: postgraduate uses eye, eye pouch, black eye weight for a long time
See that Fig. 3, right eye (picture left eye) observe eye pouch diminution, black eye recession, canthus using primary, comparison left eye
It is promoted, pupil exposure increases.
Case two: product designer often works overtime, and eye pouch is deep, canthus is sagging
After seeing that Fig. 4, right eye (picture left eye) are used once, left eye is compared, eye pouch reduces, and canthus is promoted, and pupil exposes increasing
Add.
Case three: laboratory student stays up late for a long time, all night, eye relaxation are obvious once in a while
See that Fig. 5, right eye (picture left eye) are promoted using primary rear variation, canthus, eye part skin is obviously compact, pupil exposure
Increase, the color of the white of the eye and pupil is limpid.
Case four: enterpriser drinks all the year round, stays up late, treats with courtesy, and eye pouch is deep, canthus is sagging, eye is without mind
After seeing that Fig. 6, left eye (picture right eye) are used once, right eye is compared, red capillary is reduced, eye pouch partial remission, black eye
Circle mitigates, eye circumference is compact.
Case five: retired teacher's eyes are dim-sighted, muddy, eye pouch weight
After seeing that Fig. 7, left eye (picture right eye) are used once, right eye is compared, eye pouch is reduced, and periocualr skin is compact, and eyes have
Mind.
Case six: junior, often have stay up late all night, game, eye have serious black eye
After seeing that Fig. 8, right eye (picture left eye) are used once, left eye is compared, black eye mitigates.
Case seven: company clerk, through commonly using eye
After seeing that Fig. 9, right eye (picture left eye) are used once, left eye is compared, black eye and eye pouch mitigate, and canthus is promoted.
Case eight: company clerk, through commonly using eye
See that Figure 10, eyes are used, adheres to that once every two days, using two weeks, black eye mitigated, eyeball exposure increases, the white of the eye
Increase with eyeball contrast.
Embodiment 2: it is a kind of so that canthus is raised up, the preparation method for the liquid preparation that eye loosens, its step are as follows:
It smashes: taking dry Roots of Panax Notoginseng, Selaginella tamariscina herb, radix tetrastigme root, crushed respectively by pulverizer, respectively obtain Radix Notoginseng
Powder, Spikemoss, radix tetrastigme powder, it is spare；
It impregnates: the dry corn stigma of 1800g Notoginseng Root, 500g Spikemoss, 1200g radix tetrastigme powder and 1500g is set
Do not had herb powder 30cm high in 60 degree of liquor made from sorghums in 50L ceramic vessel, are added, impregnated 3 months.
Filtering: two layers of crocus cloth of medical fluid is filtered；
It impregnates again: 60 degree of liquor made from sorghums being added into filter residue, do not had filter residue 5cm high, impregnate 3 months.
It refilters: two layers of crocus cloth of medical fluid is filtered；
Revolving: merging filtrate twice, rotates evaporimeter using vacuum, and 60 revs/min of revolving speed, 55 DEG C of bath temperature.At this
Under the conditions of, the volatile substances such as ethyl alcohol can preferential volatilization, water can also evaporate in right amount, condensation liquor collecting device after ten minutes there is no
Condensate liquid generates, and is considered as ethyl alcohol volatilization completely, is sterilized by ultraviolet light irradiation, obtain aqueous liquid preparation, is applied by practical eye
Observation, it is nonirritant.
Liquid preparation prepared by embodiment 2 is used for different study subjects:
Application method: taking liquid preparation drop in eye cotton pads, and infiltration is drenched, closes eyes, cotton pads is covered in
Eye is removed after 20min, is massaged into and fully absorbs, take pictures after 10min.
Case nine: enterpriser drinks all the year round, treats with courtesy, and eye pouch longhole is without mind, black eye weight
See that Figure 11, right eye (picture left eye) observe eye pouch diminution, black eye recession, canthus using primary, comparison left eye
It is promoted, pupil exposure increases.
Case ten: company clerk uses eye for a long time, there is eye pouch, black eye
See that Figure 12, left eye (picture right eye) observe eye pouch diminution, black eye recession, canthus using primary, comparison right eye
It is promoted, pupil exposure increases.
Embodiment 3: it is a kind of so that canthus is raised up, the preparation method for the liquid preparation that eye loosens, its step are as follows:
It smashes: taking dry Roots of Panax Notoginseng, Selaginella tamariscina herb, radix tetrastigme root, crushed respectively by pulverizer, respectively obtain Radix Notoginseng
Powder, Spikemoss, radix tetrastigme powder, it is spare；
It impregnates: the dry corn stigma of 1500g Notoginseng Root, 100g Spikemoss, 1500g radix tetrastigme powder and 2000g is set
Do not had herb powder 30cm high in 60 degree of liquor made from sorghums in 50L ceramic vessel, are added, impregnated 3 months.
Filtering: two layers of crocus cloth of medical fluid is filtered；
It impregnates again: 60 degree of liquor made from sorghums being added into filter residue, do not had filter residue 5cm high, impregnate 3 months.
It refilters: two layers of crocus cloth of medical fluid is filtered；
Revolving: merging filtrate twice, rotates evaporimeter using vacuum, and 60 revs/min of revolving speed, 55 DEG C of bath temperature.At this
Under the conditions of, the volatile substances such as ethyl alcohol can preferential volatilization, water can also evaporate in right amount, condensation liquor collecting device after ten minutes there is no
Condensate liquid generates, and is considered as ethyl alcohol volatilization completely, is sterilized by ultraviolet light irradiation, obtain aqueous liquid preparation, is applied by practical eye
Observation, it is nonirritant.
Liquid preparation prepared by embodiment 3 is used for different study subjects:
Application method: taking liquid preparation drop in eye cotton pads, and infiltration is drenched, closes eyes, cotton pads is covered in
Eye is removed after 20min, is massaged into and fully absorbs, take pictures after 10min.
Case 11: university student uses eye, eye pouch, black eye weight for a long time
See that Figure 13, right eye (picture left eye) observe eye pouch diminution, black eye recession, canthus using primary, comparison left eye
It is promoted, pupil exposure increases.
Case 12: university student uses eye, eye pouch, black eye weight for a long time
See that Figure 14, right eye (picture left eye) observe eye pouch diminution, black eye recession, canthus using primary, comparison left eye
It is promoted, pupil exposure increases.
Claims (8)
1. it is a kind of so that canthus is raised up, the liquid preparation that eye loosens, which is characterized in that by Chinese medicine Radix Notoginseng, Selaginella tamariscina, radix tetrastigme and
Corn stigma 60-70%(v/v) ethyl alcohol immersion, each constituents in medicinal material are extracted, it is then therein by revolving volatilization removal
It is obtained after ethyl alcohol；
The Chinese medicine Radix Notoginseng, Selaginella tamariscina, radix tetrastigme, corn stigma weight are as follows:
Chinese medicine parts by weight
Radix Notoginseng 800-2500
Selaginella tamariscina 100-500
Radix tetrastigme 500-1500
Corn stigma 500-2000.
2. by liquid preparation described in claim 1, which is characterized in that the Radix Notoginseng be fresh Panax notoginseng root cleaned, dried,
Smashed powder；
The Selaginella tamariscina be fresh Selaginella tamariscina herb cleaned, dried, smashed powder；
The radix tetrastigme be fresh radix tetrastigme root cleaned, dried, smashed powder；
The corn stigma is gained after fresh corn silk is cleaned, dried.
3. by liquid preparation as claimed in claim 2, which is characterized in that the Chinese medicine Radix Notoginseng, Selaginella tamariscina, radix tetrastigme, corn stigma
Weight are as follows:
Chinese medicine parts by weight
Radix Notoginseng 1000-2000
Selaginella tamariscina 100-500
Radix tetrastigme 800-1200
Corn stigma 1000-2000.
4. by liquid preparation as claimed in claim 3, which is characterized in that the Chinese medicine Radix Notoginseng, Selaginella tamariscina, radix tetrastigme, corn stigma
Weight are as follows:
Chinese medicine parts by weight
Radix Notoginseng 2000
Selaginella tamariscina 200
Radix tetrastigme 1000
Corn stigma 2000.
5. making canthus raise up described in a kind of claim 2-4 is any, the preparation method for the liquid preparation that eye loosens, step is such as
Under:
(1) take Radix Notoginseng, Selaginella tamariscina, radix tetrastigme and corn stigma to be placed in container, 60-70%(v/v be added) ethyl alcohol, impregnates and does not cross Chinese medicine
Material powder 10-30cm impregnates 3-6 months；
(2) filtrate is obtained by filtration；
(3) 60-70%(v/v is added into filtering gained sediment) ethyl alcohol, impregnates and does not cross sediment 5-10cm, impregnate 1-3
Month；
(4) filtrate is obtained by filtration；
(5) filtrate obtained by step (2) and (4) is merged, is volatilized completely by vacuum decompression revolving distillation to ethyl alcohol, obtains liquid
Preparation.
6. the preparation method as described in claim 5, which is characterized in that middle revolving speed 50-70 turns of the revolving distillation setting of step (5)/
Minute, 50-60 DEG C of bath temperature.
7. by preparation method as claimed in claim 6, which is characterized in that the liquid preparation yellow, sticky and easy wire drawing for color
It is liquid, it include main component water, amino acid, mucin and polysaccharide.
8. any liquid preparation is preparing the application in eye skin care item in claim 2-4.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258442A (en) * | 2011-07-15 | 2011-11-30 | 广州市娇兰化妆品有限公司 | Compound traditional Chinese medicine extract and application thereof to whitening, moisturizing and anti-aging skin care product |
| CN102274141A (en) * | 2011-07-15 | 2011-12-14 | 广州市娇兰化妆品有限公司 | Herba selaginellae revival moisturizing cream and preparation method thereof |
| DE102017117125A1 (en) * | 2017-07-28 | 2019-01-31 | Fubing Li | Chinese medicine for the removal of crow's feet |
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2019
- 2019-08-19 CN CN201910765067.7A patent/CN110327433B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258442A (en) * | 2011-07-15 | 2011-11-30 | 广州市娇兰化妆品有限公司 | Compound traditional Chinese medicine extract and application thereof to whitening, moisturizing and anti-aging skin care product |
| CN102274141A (en) * | 2011-07-15 | 2011-12-14 | 广州市娇兰化妆品有限公司 | Herba selaginellae revival moisturizing cream and preparation method thereof |
| DE102017117125A1 (en) * | 2017-07-28 | 2019-01-31 | Fubing Li | Chinese medicine for the removal of crow's feet |
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