CN111110817A

CN111110817A - Traditional Chinese medicine composition for treating eye diseases, preparation method and application thereof

Info

Publication number: CN111110817A
Application number: CN202010073841.0A
Authority: CN
Inventors: 李强
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-01-22
Filing date: 2020-01-22
Publication date: 2020-05-08

Abstract

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating eye diseases, a preparation method and application thereof. The Chinese medicinal composition comprises water, flos Chrysanthemi, pericarpium Citri Reticulatae viride, Alumen, Borneolum Syntheticum, Coptidis rhizoma, rhizoma Zingiberis recens juice and transdermal agent. The preparation method comprises the following steps: s1, grinding menthol, rutabaga and garden balsam stem into powder, soaking in a mixed solution of laurocapram, propylene glycol and alcohol, and performing solid-liquid separation to obtain a transdermal agent; s2, mixing flos Chrysanthemi, pericarpium Citri Reticulatae viride, Alumen, rhizoma Coptidis and Borneolum Syntheticum, pulverizing, and sieving to obtain mixed powder; s3, mixing the mixed powder, ginger juice and transdermal agent, stirring, adding water, and making into cream to obtain the Chinese medicinal composition. The traditional Chinese medicine composition prepared by the method can be used as a medicine for treating eye diseases such as myopia, hypermetropia, glaucoma, muscae volitantes and optic atrophy, and solves the problem that the medicine in the current market is difficult to effectively treat the eye diseases such as myopia, hypermetropia, glaucoma, muscae volitantes and optic atrophy.

Description

Traditional Chinese medicine composition for treating eye diseases, preparation method and application thereof

Technical Field

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating eye diseases, a preparation method and application thereof.

Background

The eyes are one of the important organs of the human body, and once eye diseases occur, the eyesight of a patient is affected, and physical pain is brought to the patient. In particular, myopia, hypermetropia, glaucoma, muscae volitantes, optic atrophy and the like are eye diseases which have a high incidence in recent years. Eyes are open to five zang organs and six fu organs, and virtually any eye disease (except eye trauma) is caused by dysfunction of zang-fu organs, obstructed meridians and collaterals, and upward penetration of qi, blood and body fluids of human body to eyes. The pathological changes of the eyes are an external manifestation of the breakdown of the zang-fu organs, meridians and collaterals, visual pathways, etc.

According to the theory of traditional Chinese medicine, myopia is caused by congenital heredity due to the deficiency of innate essence and deficiency of liver and kidney, the absence of essence and blood to lift the eyes and nourish them, and the inability of spirit to go beyond the eyes. The spleen and stomach are the acquired root, the qi and blood are the source of transformation, and the spleen and stomach are weakened, so the spleen and stomach are lifted, transported and transformed, the eyes cannot receive blood, the spirit cannot be seen far, and the heart-yang is weakened due to exhaustion. Deficiency of yang causes excess of yin, yang is yin invasion and consumes liver blood, and due to liver blood deficiency, the eyes cannot be nourished and the veins are blocked, so that qi stagnation and blood stasis, eye collaterals are blocked, essence and blood cannot nourish the eyes, qi and blood deficiency occurs, people work for exhaustion, fine carving, long-term vision impairment, liver blood damage, dry and unsmooth meridians in the eyes, fine veins and insufficient qi and blood, and myopia is formed.

Hyperopia refers to an ocular condition in which distance vision is more clear than near vision. The main causes of the disease are astringing yin, deficiency of kidney yin and failure of convergence of light bloom in the eyes; deficient innate endowment or deficiency of liver and kidney, light bloom in the eyes and diffuse, resulting in inability to see near.

According to the traditional Chinese medicine, the blind (glaucoma) means that the eye is basically not abnormal, the pupil is clear in black and white, and the eyes cannot see the ears. However, the essence and qi of the five zang-organs and six fu-organs are all injected into the eyes, and if the zang-organs are deficient, there are pathogenic phlegm and retained fluid, there is heat which can cause red pain, there is no heat but produces cockroach, so the appearance is not different, and only what is not seen is called the blindness.

The traditional Chinese medicine calls that the muscae volitantes is clouded eye moving, which means that the eyes have good appearance and feel like flies or cloud-like black shadows flying in front of the eyes and even blurred vision. The main causes of the disease are: damp-heat with phlegm-fire, stagnation and steaming, turbid qi invading the clear orifices; liver qi stagnation, qi stagnation and blood stasis, liver yang hyperactivity, damage to vessels and blood outflow from collaterals; deficiency of the liver and kidney, hyperactivity of fire due to yin deficiency, consumption of essence and fluid, deficiency of qi and blood, and malnutrition of the eyes.

At present, no specific medicine for treating eye diseases such as myopia, hypermetropia, glaucoma, muscae volitantes, optic atrophy and the like exists, and the eye diseases are usually treated by adopting an operation method. However, the treatment mode of the operation has very high requirements on the technical level of doctors, high treatment risk, long recovery time of patients and unsatisfactory treatment effect.

Disclosure of Invention

The technical problem to be solved by the invention is to provide a traditional Chinese medicine composition for treating eye diseases and a preparation method thereof, and solve the problem that the existing medicine in the market is difficult to effectively treat the eye diseases such as myopia, hypermetropia, glaucoma, muscae volitantes, optic atrophy and the like.

The technical scheme for solving the technical problems is as follows:

a Chinese medicinal composition for treating eye diseases comprises (by weight parts) water 4-13, flos Chrysanthemi 3-9, pericarpium Citri Reticulatae viride 3-9, Alumen 3-9, Borneolum 1-3, Coptidis rhizoma 1-3, rhizoma Zingiberis recens juice 3-9 and transdermal agent 3-9;

the transdermal agent comprises 0.6-1.8 parts of menthol, 0.6-1.8 parts of rutabaga, 0.6-1.8 parts of garden balsam stem, 0.6-1.8 parts of laurocapram, 0.5-1.5 parts of propylene glycol and 0.1-0.3 part of alcohol.

The white chrysanthemum is pungent, sweet, bitter and slightly cold in nature. It enters lung and liver meridians. Has the effects of dispelling wind and heat, calming liver, improving eyesight, and clearing away heat and toxic materials. Chrysanthemum is good at dispelling wind and clearing heat, clearing liver-fire, and nourishing yin to improve vision, so it is indicated for blood-shot eyes with swelling and pain due to wind-heat in liver channel or up-flaming of liver fire. The efficacies of the chrysanthemum in the book Ben Cao Zheng Yi (Chinese materia medica): all flowers are mainly used to disperse and dredge qi, while only Ju Hua is used to lower the intake, so it can calm liver fire, extinguish internal wind and suppress the transverse reversal of wood qi. For dizziness due to wind, it is indicated by yin deficiency with yang floating, rising of qi-fire and upward disturbance of liver and phoenix, and it is not exogenous wind pathogen and can cause dizziness in the book Jing. Swelling and pain, combined with wind-stroke and dizziness. Liver fire ascends directly to the vertex, and is the most intense, manifested as dizziness, swelling, pain, and ascending yang-flame. The force is almost the same as that of the head phoenix which can not shake the wind without internal fire, but chrysanthemum can treat the disease but not descend and calm the earth. The condition of the eyes should be relieved, especially the liver-yang causing the wind. The head-phoenix pain is so severe that the eyes are prominent like the sparrow egg. The eye herbs are essential for the eyes because they are deficient in yin and deficient in yang, so that liver fire ascends and yin cannot be absorbed, but wind-yang is used for dispelling and discharging, so that liver and kidney yin is deficient when the eyes face and tears, while floating yang is excessive and ascending, but chrysanthemum can purge and descend to absorb and absorb deficient yang. "

Qing Pi, the peel of immature fruit or young fruit of orange, is known as green. Qing Pi is bitter, pungent and warm in nature. It enters liver, gallbladder and stomach meridians. The pungent and pungent flavor of Qing Pi has the actions of dispersing warm and promoting diuresis, strong bitter and purgative effect and strong smell, and moves downward due to its descending and descending nature, and it is good at relieving liver, qi and pain, dissipating nodulation and resolving stagnation, especially moving qi, dispersing food stagnation and resolving stagnation. The liver governs smoothing flow of qi and has the function of regulating qi activity of human body. Qi can produce blood, promote the production of body fluid, and promote blood and body fluid production. All blood and body fluids supplied to the eyes are not driven independently by qi, and whether qi movement of the human body is regulated smoothly is closely related to the characteristic of the liver that governs ascending and initiative. Therefore, the "bier & pulse rate" records: "liver qi unblocks eyes, liver and eyes can distinguish five colors . This emphasizes that the eyes can distinguish the color from the object only if the liver qi is smooth and smooth. The green tangerine peel can soothe liver and relieve depression, can break qi stagnation and has great effect on treating eye diseases.

Alum is crystal processed with alum ore, belongs to mineral Chinese medicinal material and has the main component of potassium aluminum sulfate dodecahydrate. Alum is sour, astringent and cold in nature, enters lung, liver, spleen and large intestine channels, and has strong astringency. It has the effects of eliminating dampness, relieving itching and counteracting toxic substances, and has the effects of relieving diarrhea, stopping bleeding, clearing heat, eliminating phlegm and eliminating jaundice.

Borneol is a crystal extracted from resin and volatile oil processed product of borneol family plant, and is semitransparent crystal, and is similar to plum petal block and sheet, so that it is also called "plum slice", its colour is white to light grey brown, smell is fragrant, taste is pungent and cool, and can be used for curing heart meridian, and its smell is fragrant, pungent and fragrant, can be used for preventing foul smell and dredging nine orifices. The new repair herbal records: borneol is used to treat heart and abdomen pathogenic qi, rheumatism, deafness, vision improvement, red eyes and nebula. Borneol enters heart meridian, heart governs spirit and is called monarch organ, so it can induce resuscitation with aromatics and refresh mind. The product has effects of inducing resuscitation, refreshing mind, clearing heat, removing toxic substance, improving eyesight, and removing nebula, and can be used for treating fever, hyperpyrexia, coma, apoplexy, phlegm syncope, convulsion, summer-heat dampness covering resuscitation, pharyngitis, deafness, aphtha, swelling of teeth, skin ulcer, carbuncle, malnutritional hemorrhoid, conjunctival congestion, swelling and pain, nebula, and eye covering.

The coptis root is bitter and cold in property, enters heart, stomach, liver and large intestine channels, and has the effects of clearing heat and drying dampness, and purging fire and removing toxicity. The record in the pearl sac tonic drug property endowment: huang Lian is bitter in taste, cold in nature and nontoxic. Sinking also in yin. It is used for relieving stuffiness and fullness in the lower abdomen; governing the intestines to remove miscellaneous substances in the intestines; it is suitable for eye diseases and fulminant diseases; treat both the head and the tail of sores and ulcers. The book of Shen nong Ben Cao Jing mentions: bitter and cold in taste. It is mainly used for treating hot air, eye pain, angular injury, qi-eliminating, eye sight improving, intestine , abdominal pain, diarrhea, and female yin swelling and pain. People can not forget after taking the medicine for a long time. The record in the book of materia medica new edition is as follows: huang Lian is bitter and cold in taste, can ascend and descend, and is also nontoxic. Enter the heart and the cell collaterals. It can enter liver when purging fire. "

The rhizoma Zingiberis recens juice is prepared by cleaning rhizoma Zingiberis recens of Zingiberaceae, mashing, and mixing with the juice. Ginger, rhizoma Zingiberis recens, pungent in property and slightly warm in flavor, enters lung and spleen meridians. Its protein, fat, dietary fiber and vitamin contents are very high, and the contained gingerol and diphenyl heptane compounds have strong antioxidant and free radical scavenging effects, and can promote blood circulation, dispel cold and remove toxic substance. Rhizoma Zingiberis recens has effects of inducing sweat, relieving exterior syndrome, warming middle warmer, stopping emesis, warming lung, and relieving cough. Rhizoma Zingiberis recens has effects of relieving exterior syndrome with pungent and warm natured drugs, and can stimulate capillary vessel and improve local blood circulation.

The transdermal agent is a commonly used liquid for promoting the penetration of the medicine, generally adopts menthol, water rutabaga, garden balsam stem, laurocapram, propylene glycol and trace alcohol, promotes the penetration more quickly and accelerates the penetration of the medicine liquid.

Menthol, consisting of a saturated cyclic alcohol obtained from peppermint oil. The menthol has the function of remarkably promoting the transdermal absorption of paracetamol. The transdermal absorption mechanism of menthol for promoting paracetamol is closely related to the change of the epidermal structure, and the mechanism is that the mint promotes the transdermal of the medicine.

The cleome watercress not only can clear away lung heat and reduce phlegm, eliminate lung inflammation and clear away lung heat, but also can dilute sputum in trachea and accelerate sputum discharge. The external application of the clevervine root has the effects of relieving swelling, detoxifying and relieving itching, and can relieve the symptoms of swelling and pain.

The garden balsam stem can dredge the channels and collaterals and accelerate qi and blood circulation. Tuberculate speranskia herb enters liver meridian and liver governs tendons, so it has the effect of relaxing muscles and tendons and activating collaterals. In addition, the garden balsam stem also has the functions of dissipating blood stasis, relieving pain, promoting blood circulation, removing blood stasis, detoxifying and reducing swelling.

Laurocapram is a skin penetration enhancer, can change lipid and protein structure of skin cortex stratum, promote drug absorption through skin, and enhance skin penetration effect of hydrophilic and hydrophobic compounds. Has obvious transdermal permeation-aiding effect on both hydrophilic and lipophilic medicaments, and has good permeation-aiding effect in an emulsion or an alternate state. Practice proves that laurocapram can safely promote penetration and absorption of active ingredients on the skin.

The propylene glycol can enable the effective components in the traditional Chinese medicine composition to be better absorbed by the skin, so that the propylene glycol can be used as a penetration enhancer.

The alcohol is helpful for precipitation of effective components of the medicine, and various components of the traditional Chinese medicine are easy to dissolve in the alcohol.

The white chrysanthemum can not only disperse wind and clear heat, clear liver and purge fire, but also can nourish yin and improve eyesight, and is mainly used for treating conjunctival congestion and swelling pain caused by wind heat in liver channel or upward attack of liver fire; pericarpium Citri Reticulatae viride has effects of soothing liver and relieving qi stagnation, and eliminating stagnation of qi; alumen has antibacterial and astringent effects, and is effective in removing toxic substance, killing parasite, eliminating dampness, relieving itching, stopping bleeding, relieving diarrhea, clearing away heat, and eliminating phlegm; borneol enters heart channel, heart governs spirit and is called monarch organ, so that the borneol can induce resuscitation and refresh mind, and has the effects of inducing resuscitation and refreshing mind, clearing heat and removing toxicity, and improving eyesight and removing nebula; the coptis chinensis has the effects of clearing heat, drying dampness, purging fire, removing toxin and purging liver fire, and the liver governs eyes, so that the coptis chinensis can treat sudden attack of eye diseases; the ginger juice can stimulate capillary vessels and improve local blood circulation; the transdermal agent can promote the penetration of the medicine and help the skin to better absorb the effective components in the traditional Chinese medicine composition. The traditional Chinese medicine composition for treating eye diseases adopts white chrysanthemum, green tangerine orange peel, alum, borneol, coptis, ginger juice and transdermal agent, and can effectively treat eye diseases such as myopia, hypermetropia, glaucoma, muscae volitantes and optic atrophy.

Further, the medicine comprises, by weight, 7-11 parts of water, 5-7 parts of white chrysanthemum, 5-7 parts of green tangerine orange peel, 5-7 parts of alum, 1.5-2.5 parts of borneol, 1.5-2.5 parts of coptis root, 5-7 parts of ginger juice and 5-7 parts of transdermal agent;

the transdermal agent comprises 1-1.4 parts of menthol, 1-1.4 parts of aquatica, 1-1.4 parts of garden balsam stem, 1-1.4 parts of laurocapram, 0.85-1.15 parts of propylene glycol and 0.15-0.25 part of alcohol.

The eye disease treatment liquid is prepared from water, white chrysanthemum, green tangerine peel, alum, borneol, coptis chinensis, ginger juice, menthol, water turnip, garden balsam stem, laurocapram, propylene glycol and alcohol in parts by weight, and has better treatment effect on eye diseases such as myopia, hypermetropia, glaucoma, muscae volitantes and optic atrophy.

The invention provides an application of a traditional Chinese medicine composition in preparing a medicine for treating myopia, hypermetropia, glaucoma, muscae volitantes and optic atrophy.

The traditional Chinese medicine composition provided by the invention is mainly used as a medicine for treating eye diseases such as myopia, hypermetropia, glaucoma, muscae volitantes and optic atrophy.

The invention also provides a preparation method of the traditional Chinese medicine composition for treating eye diseases, which comprises the following steps:

s1, grinding menthol, rutabaga and garden balsam stem into powder, soaking in a mixed solution of laurocapram, propylene glycol and alcohol, and performing solid-liquid separation to obtain a transdermal agent;

s2, mixing flos Chrysanthemi, pericarpium Citri Reticulatae viride, Alumen, rhizoma Coptidis and Borneolum Syntheticum, pulverizing, and sieving to obtain mixed powder;

s3, mixing the mixed powder, ginger juice and transdermal agent, stirring, adding water, and making into cream to obtain the Chinese medicinal composition.

In S1, the menthol, the watercress and the garden balsam stem are ground into powder and soaked in the propylene glycol and the alcohol, so that the traditional Chinese medicine components in the menthol, the watercress and the garden balsam stem can be fully extracted. The purpose of adding laurocapram is to promote the penetration of the above Chinese medicinal components into human skin. In S2, flos Chrysanthemi, pericarpium Citri Reticulatae viride, Alumen, rhizoma Coptidis and Borneolum Syntheticum are mixed and pulverized to release the effective components of the Chinese medicinal materials. Step S3, mixing the mixed powder, ginger juice and transdermal agent, stirring, adding water, and making into cream, so that the ginger juice and the Chinese medicinal components in the mixed powder can be soaked into human skin. The Chinese medicinal composition prepared by the method can effectively treat eye diseases such as myopia, hypermetropia, glaucoma, muscae volitantes, optic atrophy and the like.

Further, the step S1 specifically includes:

grinding Mentholum, radix Cyathulae and caulis et folium Gaultheriae Yunnanensis into powder, soaking in mixed solution of laurocapram, propylene glycol and alcohol, performing solid-liquid separation by centrifugal separation, and collecting supernatant after solid-liquid separation to obtain transdermal agent.

In S1, the menthol, the watercress and the garden balsam stem are ground into powder and soaked in the propylene glycol and the alcohol, so that the traditional Chinese medicine components in the menthol, the watercress and the garden balsam stem can be fully extracted. The purpose of adding laurocapram is to promote the penetration of the above Chinese medicinal components into human skin. The liquid medicine and the dregs of a decoction can be separated out by adopting a solid-liquid separation mode to obtain the transdermal agent.

Further, the step S2 specifically includes:

mixing flos Chrysanthemi, pericarpium Citri Reticulatae viride, Alumen, Coptidis rhizoma and Borneolum Syntheticum, pulverizing, and sieving with 100-mesh and 150-mesh sieve to obtain mixed medicinal powder.

The white chrysanthemum, the green tangerine orange peel, the alum, the coptis chinensis and the borneol are crushed and sieved by a sieve with 150 meshes in 100 meshes, so that the effective traditional Chinese medicine components in the white chrysanthemum, the green tangerine orange peel, the alum, the coptis chinensis and the borneol can be fully released, and the fine feeling of the traditional Chinese medicine composition is ensured.

Further, before the step S1, the method further includes the following steps:

after the white chrysanthemum, the green tangerine orange peel, the coptis chinensis, the water turnip and the garden balsam stem are cleaned, the drying treatment is carried out until the water content is 0.5 to 2 percent.

Through the steps, the white chrysanthemum, the green tangerine peel, the coptis chinensis, the water turnip and the garden balsam stem are dried until the water content is 0.5-2%, so that the white chrysanthemum, the green tangerine peel, the coptis chinensis, the water turnip and the garden balsam stem are favorably crushed or ground into powder.

Further, the step S3 specifically includes:

mixing the mixed powder, rhizoma Zingiberis recens juice and transdermal agent, stirring, adding water, and adjusting to obtain cream with water content of 10-30% to obtain the Chinese medicinal composition.

The water content of the cream-shaped traditional Chinese medicine composition prepared by the invention is 10-30%, the traditional Chinese medicine composition can be ensured to be applied on the facial skin of a patient, the effective components of the traditional Chinese medicine composition can be ensured to permeate into a human body, and the traditional Chinese medicine composition is ensured not to easily slip off the skin.

Compared with the prior art, the invention has the beneficial effects that: the traditional Chinese medicine composition for treating eye diseases comprises white chrysanthemum, green tangerine orange peel, alum, borneol, coptis, ginger juice and transdermal agent. Wherein the white chrysanthemum can clear liver-fire, nourish yin and improve eyesight; pericarpium Citri Reticulatae viride has effects of dispersing stagnated liver qi, relieving qi stagnation, and eliminating stagnation of qi; alumen has antibacterial and astringent effects, and is effective in removing toxic substance, killing parasite, eliminating dampness, and relieving itching; the borneol can clear heat, remove toxicity, improve eyesight and remove nebula; rhizoma Coptidis has effects of clearing heat, eliminating dampness, purging pathogenic fire, and removing toxic substances; the ginger juice can stimulate capillary vessels and improve local blood circulation; the transdermal agent can promote the penetration of the traditional Chinese medicine components and help the skin to better absorb the effective components in the traditional Chinese medicine composition. The invention also provides a method for preparing the traditional Chinese medicine composition for treating eye diseases, and the traditional Chinese medicine composition prepared according to the method can effectively treat eye diseases such as myopia, hypermetropia, glaucoma, muscae volitantes, optic atrophy and the like.

Detailed Description

It should be noted that the following detailed description is exemplary and is intended to provide further explanation of the disclosure. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs.

It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments according to the present application. As used herein, the singular forms also include the plural forms unless the context clearly dictates otherwise, and further, it is understood that when the terms "comprises" and/or "comprising" are used in this specification, they specify the presence of the stated features, steps, operations, devices, components, and/or combinations thereof.

Hereinafter, embodiments of the present invention will be described in detail. The following examples are only for illustrating the technical solutions of the present invention more clearly, and therefore are only examples, and the protection scope of the present invention is not limited thereby.

Example 1

Preparing 4ml of water, 3 g of white chrysanthemum, 3 g of green tangerine peel, 3 g of alum, 1 g of borneol, 1 g of coptis root, 3 g of ginger juice and 3 g of transdermal agent, wherein each part is 1 g; the transdermal agent comprises 0.6 g of menthol, 0.6 g of rutabaga, 0.6 g of speranskia herb, 0.6 g of laurocapram, 0.5 g of propylene glycol and 0.1 g of alcohol.

The traditional Chinese medicine composition for treating eye diseases is prepared according to the following steps:

s11, grinding menthol, rutabaga and garden balsam stem into powder, soaking in a mixed solution of laurocapram, propylene glycol and alcohol, and performing solid-liquid separation to obtain a transdermal agent;

s12, mixing white chrysanthemum, green tangerine peel, alum, coptis chinensis and borneol, crushing, and sieving by a 100-mesh sieve to obtain mixed medicinal powder;

s13, mixing the mixed powder, ginger juice and transdermal agent, stirring, adding water, and making into cream to obtain the Chinese medicinal composition.

Typical cases are as follows: a certain Wang, acquired myopia, naked eye vision of left eye 0.5 and naked eye vision of right eye 0.6, the Chinese medicinal composition is externally applied to the double temples in the middle of the bridge of the nose of the two eyes once a day, each time is for 1 hour, and the double vision is recovered to 0.9 after three months.

Typical cases are as follows: a certain Liu is a female, the age of 42 years, the patient suffers from glaucoma for three years, the naked vision of the right eye is 0.4, the naked vision of the left eye is 0.5, the eyeballs are suffocated and painful, and the user looks at objects in a blurred way. The traditional Chinese medicine composition is externally applied to the middle of the bridge of the nose and the double temples once a day for 1 hour each time. After three months of treatment, the naked eyes of the right eye and the left eye return to 0.9. The swelling and pain of the eyeball are completely eliminated, the intraocular pressure is normal, and the eyeball does not relapse.

Example 2

Preparing 6ml of water, 4 g of white chrysanthemum, 4 g of green tangerine peel, 4 g of alum, 1.3 g of borneol, 1.3 g of coptis root, 4 g of ginger juice and 4 g of transdermal agent, wherein each part is 1 g; the transdermal agent comprises 0.8 g of menthol, 0.8 g of rutabaga, 0.8 g of speranskia herb, 0.8 g of laurocapram, 0.65 g of propylene glycol and 0.15 g of alcohol.

Firstly, cleaning white chrysanthemum, green tangerine peel, coptis chinensis, stachys sieboldii and garden balsam stem, drying until the water content is 0.5%, and preparing the traditional Chinese medicine composition for treating eye diseases according to the following steps:

s21, grinding menthol, rutabaga and garden balsam stem into powder, soaking in a mixed solution of laurocapram, propylene glycol and alcohol, performing solid-liquid separation by using a centrifugal separation method, and sucking supernatant after the solid-liquid separation to obtain a transdermal agent;

s22, mixing white chrysanthemum, green tangerine peel, alum, coptis chinensis and borneol, crushing, and sieving by a 105-mesh sieve to obtain mixed medicinal powder;

s23, mixing the mixed powder, ginger juice and transdermal agent, stirring, adding water, and adjusting to obtain cream with water content of 10% to obtain the Chinese medicinal composition.

Typical cases are as follows: some Hu, man, 36 years old. The left eye sight is fuzzy, and the inspection shows that: the left eye is hyperopic at 390 degrees and the right eye is normal. The traditional Chinese medicine composition is externally applied to the middle of the bridge of the nose and the double temples once a day for 1 hour each time, and the degree of the left eye is recovered to 50 degrees after three months.

Typical cases are as follows: zhengzhi, male, 36 years old, suffered from inflammatory optic atrophy in both eyes for 2 months. Through examination, the left eye has 420 degrees of hyperopia, the right eye has 340 degrees of hyperopia, and walking needs to be supported by others. The traditional Chinese medicine composition is externally applied to the middle of the bridge of the nose and the double temples once a day for 1 hour each time. After three months, the hypermetropia degree of the left eye is recovered to 60 degrees and the hypermetropia degree of the right eye is recovered to 50 degrees. The people can live independently, and the vision of the people is not reduced by follow-up visits till now.

Example 3

Preparing 7ml of water, 5 g of white chrysanthemum, 5 g of green tangerine peel, 5 g of alum, 1.5 g of borneol, 1.5 g of coptis root, 5 g of ginger juice and 4.5 g of transdermal agent, wherein each part is 1 g; the transdermal agent comprises 0.9 g of menthol, 0.9 g of rutabaga, 0.9 g of speranskia herb, 0.9 g of laurocapram, 0.72 g of propylene glycol and 0.18 g of alcohol.

Firstly, cleaning white chrysanthemum, green tangerine peel, coptis chinensis, stachys sieboldii and garden balsam stem, drying until the water content is 1%, and preparing the traditional Chinese medicine composition for treating eye diseases according to the following steps:

s31, grinding menthol, rutabaga and garden balsam stem into powder, soaking in a mixed solution of laurocapram, propylene glycol and alcohol, performing solid-liquid separation by using a centrifugal separation method, and sucking supernatant after the solid-liquid separation to obtain a transdermal agent;

s32, mixing white chrysanthemum, green tangerine peel, alum, coptis chinensis and borneol, crushing, and sieving by a 110-mesh sieve to obtain mixed medicinal powder;

s33, mixing the mixed powder, ginger juice and transdermal agent, stirring, adding water, and adjusting to obtain cream with water content of 15% to obtain the Chinese medicinal composition.

Typical cases are as follows: when a certain amount of Liu is in acquired myopia, the naked eye vision of the left eye is 0.7, and the naked eye vision of the right eye is 0.5, the traditional Chinese medicine composition is externally applied to the double temple in the middle of the bridge of the nose of the two eyes once a day, each time is 1 hour, and the double vision is recovered to 1.1 after four months.

Typical cases are as follows: a certain Wang is a female in age of 64 years, suffering from muscae volitantes for five years, with floating black spots in front of eyes and dry eyes, and is diagnosed as muscae volitantes caused by aging of eyes. The traditional Chinese medicine composition is externally applied to the middle of the bridge of the nose and the double temples once a day for 1 hour each time. After three months, the symptoms are greatly improved, the eyes are bright, and the comfort level of the eyes is greatly improved. The symptoms of the muscae volitantes are eliminated after five months of treatment.

Example 4

Preparing 8ml of water, 6 g of white chrysanthemum, 6 g of green tangerine peel, 6 g of alum, 1.8 g of borneol, 1.5 g of coptis root, 6 g of ginger juice and 5 g of transdermal agent, wherein each part is 1 g; the transdermal agent comprises 1 g of menthol, 1 g of rutabaga, 1 g of speranskia herb, 1 g of laurocapram, 0.8 g of propylene glycol and 0.2 g of alcohol.

Firstly, cleaning white chrysanthemum, green tangerine peel, coptis chinensis, stachys sieboldii and garden balsam stem, drying until the water content is 1.5%, and preparing the traditional Chinese medicine composition for treating eye diseases according to the following steps:

s41, grinding menthol, rutabaga and garden balsam stem into powder, soaking in a mixed solution of laurocapram, propylene glycol and alcohol, performing solid-liquid separation by using a centrifugal separation method, and sucking supernatant after the solid-liquid separation to obtain a transdermal agent;

s42, mixing white chrysanthemum, green tangerine peel, alum, coptis chinensis and borneol, crushing, and sieving by a 115-mesh sieve to obtain mixed medicinal powder;

s43, mixing the mixed powder, ginger juice and transdermal agent, stirring, adding water, and adjusting to obtain cream with water content of 20% to obtain the Chinese medicinal composition.

Typical cases are as follows: a certain Qian, male, age 54, suffered from muscae volitantes for 3 years, had black spots floating in front of eyes and dry eyes, and was diagnosed as muscae volitantes caused by aging of eyes. The traditional Chinese medicine composition is externally applied to the middle of the bridge of the nose and the double temples once a day for 1 hour each time. After one month, the symptoms are greatly improved, the eyes are bright, and the comfort level of the eyes is greatly improved. The symptoms of the muscae volitantes are eliminated after three months of treatment.

Typical cases are as follows: when certain Zhao is in certain age, acquired myopia, 0.7 naked eye vision of the left eye and 0.6 naked eye vision of the right eye are treated with the Chinese medicinal composition of the embodiment, the Chinese medicinal composition is externally applied to the points of double temples in the middle of the bridge of the two eyes once a day for 1 hour each time. After three months, the naked eye vision of the left eye is recovered to 1.2, and the naked eye vision of the right eye is recovered to 1.0.

Example 5

Preparing 9ml of water, 6.5 g of white chrysanthemum, 6.5 g of green tangerine orange peel, 6.5 g of alum, 2 g of borneol, 1.8 g of coptis root, 6.5 g of ginger juice and 6 g of transdermal agent, wherein each part is 1 g; the transdermal agent comprises 1.2 g of menthol, 1.2 g of rutabaga, 1.2 g of speranskia herb, 1.2 g of laurocapram, 0.95 g of propylene glycol and 0.25 g of alcohol.

Firstly, cleaning white chrysanthemum, green tangerine peel, coptis chinensis, stachys sieboldii and garden balsam stem, drying until the water content is 2%, and preparing the traditional Chinese medicine composition for treating eye diseases according to the following steps:

s51, grinding menthol, rutabaga and garden balsam stem into powder, soaking in a mixed solution of laurocapram, propylene glycol and alcohol, performing solid-liquid separation by using a centrifugal separation method, and sucking supernatant after the solid-liquid separation to obtain a transdermal agent;

s52, mixing white chrysanthemum, green tangerine peel, alum, coptis chinensis and borneol, crushing, and sieving by a 120-mesh sieve to obtain mixed medicinal powder;

s53, mixing the mixed powder, ginger juice and transdermal agent, stirring, adding water, and adjusting to obtain cream with water content of 25% to obtain the Chinese medicinal composition.

Typical cases are as follows: some Zhu and woman, age 42. The patient suffers from hyperopia for five years, the left eye hyperopia is 350 degrees, and the right eye hyperopia is 340 degrees. The traditional Chinese medicine composition is externally applied to the middle of the bridge of the nose and the double temples once a day for 1 hour each time, and after five months, the degree of the left eye is recovered to 63 degrees and the degree of the right eye is recovered to 45 degrees.

Typical cases are as follows: somebody of the week, male, age 43, with glaucoma for two years, naked right eye 0.5, naked left eye 0.3, eyeball swelling pain, increased intraocular pressure, and blurred vision. The traditional Chinese medicine composition is externally applied to the middle of the bridge of the nose and the double temples once a day for 1 hour each time. After four months of treatment, the naked eyes of the right eye and the left eye return to 0.9 and 0.8 respectively. The swelling and pain of the eyeball are completely eliminated, the intraocular pressure is normal, and the eyeball does not relapse.

Example 6

Preparing 10ml of water, 7 g of white chrysanthemum, 7 g of green tangerine peel, 7 g of alum, 2.2 g of borneol, 2 g of coptis root, 7 g of ginger juice and 7 g of transdermal agent, wherein each part is 1 g; the transdermal agent comprises 1.4 g of menthol, 1.4 g of rutabaga, 1.4 g of speranskia herb, 1.4 g of laurocapram, 1.15 g of propylene glycol and 0.25 g of alcohol.

Firstly, cleaning white chrysanthemum, green tangerine peel, coptis chinensis, stachys sieboldii and garden balsam stem, drying until the water content is 1.8%, and preparing the traditional Chinese medicine composition for treating eye diseases according to the following steps:

s61, grinding menthol, rutabaga and garden balsam stem into powder, soaking in a mixed solution of laurocapram, propylene glycol and alcohol, performing solid-liquid separation by using a centrifugal separation method, and sucking supernatant after the solid-liquid separation to obtain a transdermal agent;

s62, mixing white chrysanthemum, green tangerine peel, alum, coptis chinensis and borneol, crushing, and sieving by a 130-mesh sieve to obtain mixed medicinal powder;

s63, mixing the mixed powder, ginger juice and transdermal agent, stirring, adding water, and adjusting to obtain a cream with water content of 30% to obtain the Chinese medicinal composition.

Typical cases are as follows: somebody in horse, female, age 49, suffering from glaucoma for six years, naked vision of right eye 0.3, naked vision of left eye 0.4, eyeball oppression and pain, increased intraocular pressure, and blurred vision. The traditional Chinese medicine composition is externally applied to the middle of the bridge of the nose and the double temples once a day for 1 hour each time. After five months of treatment, the naked eye of the right eye is recovered to be 0.9, and the naked eye of the left eye is recovered to be 1.0. The swelling and pain of the eyeball are completely eliminated, the intraocular pressure is normal, and the eyeball does not relapse.

Typical cases are as follows: in the same place, women are 43 years old, and have inflammatory optic atrophy in both eyes for 3 months. Through examination, the right eye has 450 degrees of hyperopia, and the left eye has 410 degrees of hyperopia, and walking needs to be supported by others. The traditional Chinese medicine composition is externally applied to the middle of the bridge of the nose and the double temples once a day for 1 hour each time. Two months later, the right eye hyperopia recovered 70 degrees, and the left eye hyperopia recovered 50 degrees. The people can live independently, and the vision of the people is not reduced by follow-up visits till now.

Example 7

Preparing 11ml of water, 8 g of white chrysanthemum, 8 g of green tangerine peel, 8 g of alum, 2.5 g of borneol, 2.5 g of coptis root, 8 g of ginger juice and 8 g of transdermal agent, wherein each part is 1 g; the transdermal agent comprises 1.6 g of menthol, 1.6 g of rutabaga, 1.6 g of speranskia herb, 1.6 g of laurocapram, 1.32 g of propylene glycol and 0.28 g of alcohol.

Firstly, cleaning white chrysanthemum, green tangerine peel, coptis chinensis, stachys sieboldii and garden balsam stem, drying until the water content is 0.8%, and preparing the traditional Chinese medicine composition for treating eye diseases according to the following steps:

s71, grinding menthol, rutabaga and garden balsam stem into powder, soaking in a mixed solution of laurocapram, propylene glycol and alcohol, performing solid-liquid separation by using a centrifugal separation method, and sucking supernatant after the solid-liquid separation to obtain a transdermal agent;

s72, mixing white chrysanthemum, green tangerine peel, alum, coptis chinensis and borneol, crushing, and sieving by a 140-mesh sieve to obtain mixed medicinal powder;

s73, mixing the mixed powder, ginger juice and transdermal agent, stirring, adding water, and adjusting to obtain cream with water content of 27% to obtain the Chinese medicinal composition.

Typical cases are as follows: wang some, woman, 53 years old. The patient suffers from hyperopia for 4 years, the left eye hyperopia is 330 degrees, and the right eye hyperopia is 280 degrees. The traditional Chinese medicine composition is externally applied to the middle of the bridge of the nose and the double temples once a day for 1 hour each time, and after five months, the degree of the left eye is recovered to 50 degrees and the degree of the right eye is recovered to 40 degrees.

Typical cases are as follows: some von Decipiens, male, age 58, both eyes suffering from inflammatory optic atrophy for 3 months. Through examination, the right eye has 500 degrees of hyperopia and the left eye has 430 degrees of hyperopia, and walking needs to be supported by others. The traditional Chinese medicine composition is externally applied to the middle of the bridge of the nose and the double temples once a day for 1 hour each time. Three months later, the right-eye hyperopia recovered to 80 degrees, and the left-eye hyperopia recovered to 60 degrees. The people can live independently, and the vision of the people is not reduced by follow-up visits till now.

Example 8

Preparing 13ml of water, 9 g of white chrysanthemum, 9 g of green tangerine peel, 9 g of alum, 3 g of borneol, 3 g of coptis, 9 g of ginger juice and 9 g of transdermal agent, wherein each part is 1 g; the transdermal agent comprises 1.8 g of menthol, 1.8 g of rutabaga, 1.8 g of speranskia herb, 1.8 g of laurocapram, 1.5 g of propylene glycol and 0.3 g of alcohol.

Firstly, cleaning white chrysanthemum, green tangerine peel, coptis chinensis, stachys sieboldii and garden balsam stem, drying until the water content is 1.2%, and preparing the traditional Chinese medicine composition for treating eye diseases according to the following steps:

s81, grinding menthol, rutabaga and garden balsam stem into powder, soaking in a mixed solution of laurocapram, propylene glycol and alcohol, performing solid-liquid separation by using a centrifugal separation method, and sucking supernatant after the solid-liquid separation to obtain a transdermal agent;

s82, mixing white chrysanthemum, green tangerine peel, alum, coptis chinensis and borneol, crushing, and sieving by a 150-mesh sieve to obtain mixed medicinal powder;

s83, mixing the mixed powder, ginger juice and transdermal agent, stirring, adding water, and adjusting to cream with water content of 17% to obtain the Chinese medicinal composition.

Typical cases are as follows: a certain Liu, hereditary myopia, 0.6 of naked eye vision of the left eye and 0.6 of naked eye vision of the right eye is externally applied to the double temples in the middle of the bridge of the nose of the two eyes once a day for 1 hour each time, and the double-eye vision is recovered to 1.0 after six months.

Typical cases are as follows: somebody in sun, male, age 34, suffered from inflammatory optic atrophy in both eyes for 4 months. Through examination, the right eye has 370 degrees of hyperopia, the left eye has 330 degrees of hyperopia, the visual environment is clear and light, the tongue is red, ecchymosis exists, the tongue coating is thin and white, the pulse is thready and wiry, and the walking needs to be supported by other people. The traditional Chinese medicine composition is externally applied to the middle of the bridge of the nose and the double temples once a day for 1 hour each time. Three months later, the right eye hyperopia recovered to 60 degrees, and the left eye hyperopia recovered to 50 degrees. The people can live independently, and the vision of the people is not reduced by follow-up visits till now.

In summary, the invention provides a traditional Chinese medicine composition taking white chrysanthemum, green tangerine orange peel, alum, borneol, coptis, ginger juice and transdermal agent as raw materials and a preparation method thereof. The typical cases prove that the traditional Chinese medicine composition prepared by the method can effectively treat eye diseases such as myopia, hypermetropia, glaucoma, muscae volitantes, optic atrophy and the like.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims

1. A traditional Chinese medicine composition for treating eye diseases is characterized by comprising, by weight, 4-13 parts of water, 3-9 parts of white chrysanthemum, 3-9 parts of green tangerine orange peel, 3-9 parts of alum, 1-3 parts of borneol, 1-3 parts of coptis chinensis, 3-9 parts of ginger juice and 3-9 parts of transdermal agent;

2. The traditional Chinese medicine composition for treating eye diseases according to claim 1, which comprises, by weight, 7-11 parts of water, 5-7 parts of feverfew, 5-7 parts of green tangerine orange peel, 5-7 parts of alum, 1.5-2.5 parts of borneol, 1.5-2.5 parts of coptis chinensis, 5-7 parts of ginger juice and 5-7 parts of transdermal agent;

3. Use of a Chinese medicinal composition according to any one of claims 1-2 for the manufacture of a medicament for the treatment of myopia, hyperopia, glaucoma, muscae volitantes and optic atrophy.

4. A method of preparing a composition as claimed in any one of claims 1 to 2 for treating an ocular disorder, comprising the steps of:

5. The method as set forth in claim 4, wherein the step S1 includes:

6. The method as set forth in claim 4, wherein the step S2 includes:

7. The method for preparing a Chinese medicinal composition for treating ophthalmic diseases as claimed in claim 4, wherein before step S1, the method further comprises the following steps:

cleaning white chrysanthemum, green tangerine orange peel, coptis root, stachys sieboldii and garden balsam stem, and drying until the water content is 0.5-2%.

8. The method as set forth in claim 4, wherein step S3 includes the steps of: