CN107582771A - Stick eyelid alleviation visual fatigue sticks preparation and preparation method thereof - Google Patents
Stick eyelid alleviation visual fatigue sticks preparation and preparation method thereof Download PDFInfo
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- CN107582771A CN107582771A CN201711018694.1A CN201711018694A CN107582771A CN 107582771 A CN107582771 A CN 107582771A CN 201711018694 A CN201711018694 A CN 201711018694A CN 107582771 A CN107582771 A CN 107582771A
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Abstract
Stick eyelid alleviation visual fatigue sticks preparation and preparation method thereof, and it belongs to field of medicaments.The present invention is mainly made up of seed of feather cockscomb, the fruit of glossy privet, cassia seed, pearl, calcined and quenched CALAMINA, grass-leaved sweetflag, peppermint, storax, chrysanthemum, mulberry leaf, borneol, ethylparaben, cod-liver oil, animal bile, pure water.The present invention directly sticks 10 minutes new technologies that can alleviate above-mentioned symptom of eyelid when using, conveniently, safely, evident in efficacy.It is safe to use, conveniently, it is effective be used for alleviating visual fatigue stick preparation, energy rapid recovery visual fatigue, it is horizontal to improve eye hygiene, pre- myopia prevention, used simultaneously suitable for crowds such as cataract, vitreous opacity, macular degeneration, retinal detachment, dacryocystitises, the alleviation of the not in good time symptom of eyes, refreshment eyesight improving.
Description
Technical field
The invention belongs to field of medicaments;More particularly to it is a kind of stick eyelid and alleviate visual fatigue stick preparation and its preparation side
Method.
Background technology
With extensive use of the extensive use and telecomputer of mobile phone in people live, regarded caused by excess eye-using tired
Labor has had a strong impact on the health of people.Excess eye-using can cause eye fatigue, and kopiopia is a kind of ophthalmology common disease, and it is drawn
The eye risen is done, eye is puckery, eye is sour swollen, and blurred vision even visual impairment directly affects the work and life of people.Kopiopia is main
When being due to that people usually concentrate to see computer screen, eyes number of winks is reduced, and causes tears Secretion to reduce, simultaneously
Flash caused by the intense stimulus eyes of fluorescent screen.It can cause the corresponding sites such as the neck of people, shoulder pain occur, can also trigger and add
The various illness in eye of weight.Ophthalmic administration is all based on eye drops, ointment formulation all the time, because eye drops, ointment are directly used in rainbow
Film, sclera, be also all based on relief of symptoms, and in-convenience in use, there is fear in user, irritation, while
In the presence of because eye circumference enclose it is unclean and caused by ocular infections situations such as also happen occasionally.
The content of the invention
It is an object of the present invention to provide it is a kind of it is safe to use, conveniently, effectively stick eyelid and alleviate visual fatigue and stick system
Agent and preparation method thereof, energy rapid recovery visual fatigue, eye hygiene level, pre- myopia prevention are improved, while be applied to cataract, green grass or young crops
The crowds such as light eye, vitreous opacity, macular degeneration, retinal detachment, dacryocystitis use the alleviation of the not in good time symptom of eyes, restoring consciouness
Improving eyesight.
The present invention is achieved through the following technical solutions:
It is a kind of stick that eyelid alleviates visual fatigue stick preparation, it is described stick that eyelid alleviates visual fatigue stick preparation master
If by seed of feather cockscomb, the fruit of glossy privet, cassia seed, pearl, calcined and quenched CALAMINA, grass-leaved sweetflag, peppermint, storax, chrysanthemum, mulberry leaf, borneol, Buddhist nun
Golden ethyl ester, cod-liver oil, animal bile, pure water is moored to be made, its parts by weight be respectively 130~180 parts seed of feather cockscomb, 130~
180 parts of the fruit of glossy privet, 150~200 parts of cassia seed, 10~20 parts of pearl, 200~250 parts of calcined and quenched CALAMINA, 200~250
Part grass-leaved sweetflag, 230~270 parts of peppermint, 220~260 parts of storax, 250~350 parts of chrysanthemum, 250~350 parts
Mulberry leaf, 10~20 parts of borneol, 10~20 parts of ethylparaben, 20~50 parts of cod-liver oil, 20~50 parts of animal bile,
7500~8500 parts of pure water.
The preparation that sticks of the present invention for sticking eyelid and alleviating visual fatigue, the described patch for sticking eyelid and alleviating visual fatigue
The parts by weight for applying seed of feather cockscomb in preparation are 130 parts, and the parts by weight of the fruit of glossy privet are 130 parts, and the parts by weight of cassia seed are 150
Part, the parts by weight of pearl are 10 parts, and the parts by weight of calcined and quenched CALAMINA are 200 parts, and the parts by weight of grass-leaved sweetflag are 200 parts, thin
The parts by weight of lotus are 230 parts, and the parts by weight of storax are 220 parts, and the parts by weight of chrysanthemum are 250 parts, the weight of mulberry leaf
Number is 250 parts, and the parts by weight of borneol are 10 parts, and the parts by weight of ethylparaben are 10 parts, the parts by weight of cod-liver oil
For 20 parts, the parts by weight of animal bile are 20 parts, and the parts by weight of pure water are 7500 parts.
The preparation that sticks of the present invention for sticking eyelid and alleviating visual fatigue, the described patch for sticking eyelid and alleviating visual fatigue
The parts by weight for applying seed of feather cockscomb in preparation are 180 parts, and the parts by weight of the fruit of glossy privet are 180 parts, and the parts by weight of cassia seed are 200
Part, the parts by weight of pearl are 20 parts, and the parts by weight of calcined and quenched CALAMINA are 250 parts, and the parts by weight of grass-leaved sweetflag are 250 parts, thin
The parts by weight of lotus are 270 parts, and the parts by weight of storax are 260 parts, and the parts by weight of chrysanthemum are 350 parts, the weight of mulberry leaf
Number is 350 parts, and the parts by weight of borneol are 20 parts, and the parts by weight of ethylparaben are 20 parts, the parts by weight of cod-liver oil
For 50 parts, the parts by weight of animal bile are 50 parts, and the parts by weight of pure water are 8500 parts.
The preparation that sticks of the present invention for sticking eyelid and alleviating visual fatigue, the described patch for sticking eyelid and alleviating visual fatigue
The parts by weight for applying seed of feather cockscomb in preparation are 150 parts, and the parts by weight of the fruit of glossy privet are 150 parts, and the parts by weight of cassia seed are 180
Part, the parts by weight of pearl are 15 parts, and the parts by weight of calcined and quenched CALAMINA are 210 parts, and the parts by weight of grass-leaved sweetflag are 210 parts, thin
The parts by weight of lotus are 240 parts, and the parts by weight of storax are 240 parts, and the parts by weight of chrysanthemum are 300 parts, the weight of mulberry leaf
Number is 300 parts, and the parts by weight of borneol are 10 parts, and the parts by weight of ethylparaben are 10 parts, the parts by weight of cod-liver oil
For 35 parts, the parts by weight of animal bile are 35 parts, and the parts by weight of pure water are 8000 parts.
The preparation method of the present invention that stick preparation for sticking eyelid and alleviating visual fatigue, comprises the following steps:
Step 1, seed of feather cockscomb, the fruit of glossy privet, cassia seed, pearl, the forge furnace for weighing according to parts by weight certain mass respectively are sweet
Stone, grass-leaved sweetflag, peppermint, storax, chrysanthemum, mulberry leaf, pure water, load weighted pure water is divided into three according to parts by weight
Part, by load weighted seed of feather cockscomb, the fruit of glossy privet, cassia seed, pearl, calcined and quenched CALAMINA, grass-leaved sweetflag, peppermint, storax, chrysanthemum, mulberry leaf
It is soaked in a pure water, soak time 2h, it is standby obtains mixture A;
Step 2, the soaked mixture A of step 1 is carried out to boiling to boiling, after holding fluidized state 30min, by decoction
Extrusion, obtains concentrate A, use of separately purchasing, the dregs of a decoction is soaked in a pure water again, obtain mixture B;
Step 3, the mixture B for obtaining step 2 carry out boiling to boiling, and after keeping fluidized state 30min, decoction is squeezed
Go out, obtain concentrate B, use of separately purchasing, the dregs of a decoction are soaked in a pure water again, obtain mixture C;
Step 4, the mixture C for obtaining step 3 carry out boiling to boiling, and after keeping fluidized state 30min, decoction is squeezed
Go out, obtain concentrate C, concentrate A, concentrate B, concentrate C are mixed, obtain concentrating medicine after 300 mesh sieve net filtrations
Liquid;
Step 5, borneol, ethylparaben, cod-liver oil, the animal bile for weighing according to parts by weight certain mass respectively,
After load weighted borneol, cod-liver oil, animal bile stirring are added into concentrated medicament made from step 4, delay under conditions of stirring
Slowly add load weighted ethylparaben, stand 30~60min, obtain it is described stick that eyelid alleviates visual fatigue stick preparation
It is stand-by;
Step 6, by non-woven fabrics be soaked in it is described stick that eyelid alleviates visual fatigue stick 1~3min in preparation, afterwards
It is fitted into plastic-aluminum overlay film bag and seals, is made containing the described eye sticker for sticking preparation for sticking eyelid and alleviating visual fatigue.
The preparation method of the present invention that stick preparation for sticking eyelid and alleviating visual fatigue, described sticks eyelid alleviation
The working environment of the preparation method for sticking preparation of visual fatigue is 18~26 DEG C of room temperature, relative humidity 45~65%, clean rank
100000 grades.
The preparation method of the present invention that stick preparation for sticking eyelid and alleviating visual fatigue, non-woven fabrics is length in step 6
Square non-woven fabrics, the length of non-woven fabrics is 5.5~6cm, and width is 2.5~3.5cm, and thickness is 0.05~0.15cm.
The preparation method of the present invention that stick preparation for sticking eyelid and alleviating visual fatigue, soaks in non-woven fabrics in step 6
The described preparation that sticks for sticking eyelid alleviation visual fatigue of bubble is 1.8~2.2g.
The seed of feather cockscomb in preparation that sticks of the present invention for sticking eyelid alleviation visual fatigue is the drying of amaranthaceous plant Celosia argentea
Mature seed, there is the effect of clearing liver and improving vision, clearing heat-fire, removing nebula.Cure mainly red eye, swell pain;Screen of looking unfamiliar film;Blurring of vision;
High blood pressure;Nosebleed epistaxis;Skin wind-heat itch;Sore tinea, liver void mesh disease is unsuitable alone, and mydriasis, glaucoma patient prohibit clothes.
The fruit of glossy privet in preparation that sticks of the present invention for sticking eyelid alleviation visual fatigue is that kidney tonifying enriching yin, nourishing the liver are bright simply
Purpose Chinese medicine, the illnesss such as kidney deficiency and liver, dizzy syrigmus, graying of hair and two blurred visions paste can be controlled, the mesh for the deficiency of liver-yin and kidney-yin is dark not
It is bright, hypopsia, poliosis, soreness of waist tinnitus and fever due to yin deficiency etc..The product energy tonifying liver kidney yin, the efficacy of a drug are gentle.Mesh is controlled secretly to fail to understand,
Often match somebody with somebody cultivated land, Semen Cuscutae, matrimony vine is equally used.
It is of the present invention stick eyelid alleviate visual fatigue stick cassia seed in preparation be legume Cassia or it is small certainly
Bright dry mature seed, with its have improving eyesight work(and name it.Autumn harvests ripening fruits, dries, lays seed, except impurity elimination
Matter.Cassia seed bitter, sweet, salty, cold nature, enter liver, kidney, large intestine channel;Relax bowel, lipid-loweringing improving eyesight, treat constipation and high fat of blood,
Hypertension.Clear liver and improve vision, sharp water defaecation, there is laxative action, reducing blood pressure and blood fat.
The calcined and quenched CALAMINA in preparation that sticks of the present invention for sticking eyelid alleviation visual fatigue is that carbonate mineral side solves
Stone race smithsonite, master contain zinc carbonate.After excavation, clean, dry, except impurity elimination stone.This product character is block aggregate, in irregular
Bulk, canescence or pale red.Surface mealiness, it is matt, it is uneven, it is porous, like cellular.Body is light, frangible.It is odorless,
Taste micro-puckery.Major function:Detoxify removing nebula, the antipruritic sore of hygroscopic.For red eye, swell pain, blepharitis cililiaris etc..
It is of the present invention stick eyelid and alleviate visual fatigue stick grass-leaved sweetflag category Araeceae, Acorus dogstail in preparation
Shape herbaceos perennial, its rhizome tool smell.Leaf full edge, line up two row, spadix (spadix), bennet green, Buddhist
Flame bract shape.Rhizome often makees medicine dampness elimination appetizing, slit phlegm of having one's ideas straightened out, inducing resuscitation intelligence development.
The storax in preparation that sticks of the present invention for sticking eyelid alleviation visual fatigue is Hamamelidaceae Plants storax
The secreted resin of tree has antibacterial, antiinflammatory action, available for various respiratory tract infection.Storax also has gentle stimulation,
It can alleviate inflammation for local, such as eczema and itch, and the healing of ulcer and wound can be promoted.
It is of the present invention that to stick eyelid to alleviate the mulberry leaf intact leaf in preparation that sticks of visual fatigue be in or width egg shape to be about
15 centimetres, wide about 10 centimetres, petiole is about 4 centimetres, and blade base is heart-shaped, the micro- point in top, and there is a sawtooth at edge, and vein is dense white
Pubescence.The thicker dirty-green of old leaf.Tender leaf is relatively thin, yellow green.Matter is crisp easily, holds prick the hand.Gas is light, and mildly bitter flavor is puckery.It is medicinal typically to recognize
It is good for the person's of adopting matter after frost.Mulberry leaf have dispelling wind and heat from the body, clearing away the lungheat and moisturizing, the effect of clearing liver and improving vision.And having treatment anemopyretic cold, lung heat is dry
Cough, dizziness headache, the dim-sighted effect of hot eyes.
The cod-liver oil in preparation that sticks of the present invention for sticking eyelid alleviation visual fatigue is the liver from shark, cod etc.
In the fat that extract, yellow, there is fishy smell, mainly contain vitamin A and vitamin D.It is usually used in preventing and treating yctalopia.
Of the present invention to stick eyelid to alleviate the preparation that sticks of visual fatigue be yellow or yellowish-brown liquid, the eye sticker of preparation
For gel emplastrum.
It is of the present invention to stick the animal bile in preparation that sticks that eyelid alleviates visual fatigue and have that clearing heat and detoxicating, soothing the liver is bright
The effect of mesh, desinsection hemostasis.
It is of the present invention stick eyelid and alleviate visual fatigue stick preparation, close mesh, directly stick eyelid 10 minutes
Alleviate the new technology of above-mentioned symptom, conveniently, safely, evident in efficacy.It is safe to use, conveniently, effective be used for alleviating visual fatigue
Stick preparation, can rapid recovery visual fatigue, it is horizontal to improve eye hygiene, pre- myopia prevention, at the same suitable for cataract,
The crowds such as vitreous opacity, macular degeneration, retinal detachment, dacryocystitis use, the alleviation of the not in good time symptom of eyes, and restoring consciouness is bright
Mesh.
Embodiment
Embodiment one:
The preparation method for sticking preparation that eyelid alleviation visual fatigue is sticked in present embodiment is carried out in the steps below:
Step 1, according to parts by weight be 130 parts of seed of feather cockscomb, 130 parts of the fruit of glossy privet, 150 parts of cassia seed, 10 parts of pearl, forge furnace
Sweet 200 parts of stone, 200 parts of grass-leaved sweetflag, 230 parts of peppermint, 220 parts of storax, 250 parts of chrysanthemum, 250 parts of mulberry leaf, 10 parts of borneol, Ni Bo
Golden 10 parts of ethyl ester, 20 parts of cod-liver oil, 20 parts of animal bile, 7500 parts of pure water weigh respectively seed of feather cockscomb, the fruit of glossy privet, cassia seed,
It is pearl, calcined and quenched CALAMINA, grass-leaved sweetflag, peppermint, storax, chrysanthemum, mulberry leaf, borneol, ethylparaben, cod-liver oil, animal bile, pure
Water purification, load weighted pure water is divided into three parts according to parts by weight, by load weighted seed of feather cockscomb, the fruit of glossy privet, cassia seed,
Pearl, calcined and quenched CALAMINA, grass-leaved sweetflag, peppermint, storax, chrysanthemum, mulberry leaf are soaked in a pure water, soak time 2h, are obtained
Mixture A is standby;
Step 2, the soaked mixture A of step 1 is carried out to boiling to boiling, after holding fluidized state 30min, by decoction
Extrusion, obtains concentrate A, use of separately purchasing, the dregs of a decoction is soaked in a pure water again, obtain mixture B;
Step 3, the mixture B for obtaining step 2 carry out boiling to boiling, and after keeping fluidized state 30min, decoction is squeezed
Go out, obtain concentrate B, use of separately purchasing, the dregs of a decoction are soaked in a pure water again, obtain mixture C;
Step 4, the mixture C for obtaining step 3 carry out boiling to boiling, and after keeping fluidized state 30min, decoction is squeezed
Go out, obtain concentrate C, concentrate A, concentrate B, concentrate C are mixed, obtain concentrating medicine after 300 mesh sieve net filtrations
Liquid;
Step 5, load weighted borneol, cod-liver oil, animal bile stirring added made from step 4 after concentrated medicament,
Load weighted ethylparaben is slowly added under conditions of stirring, stands 40min, the described eyelid that sticks is obtained and alleviates visual fatigue
To stick preparation stand-by;
Step 6, by non-woven fabrics be soaked in it is described stick that eyelid alleviates visual fatigue stick 3min in preparation, load afterwards
Seal, be made containing the described eye sticker for sticking preparation for sticking eyelid and alleviating visual fatigue in plastic-aluminum overlay film bag.
The preparation method for sticking preparation for sticking eyelid and alleviating visual fatigue described in present embodiment, described sticks eyelid
The working environment for alleviating the preparation method for sticking preparation of visual fatigue is 20 DEG C of room temperature, relative humidity 45%, clean rank 100,000
Level.
The preparation method for sticking preparation for sticking eyelid and alleviating visual fatigue described in present embodiment, non-woven fabrics in step 6
For rectangle non-woven fabrics, the length of non-woven fabrics is 5.5cm, width 2.5cm, thickness 0.05cm.
The preparation method for sticking preparation for sticking eyelid and alleviating visual fatigue described in present embodiment, non-woven fabrics in step 6
The preparation that sticks for sticking eyelid alleviation visual fatigue described in middle immersion is 2g.
Prepared by present embodiment sticks the eye sticker for sticking preparation that eyelid alleviates visual fatigue, carries out irritation test survey
Examination, method of testing are divided into multiple intact skin irritant test and disposable damaged skin irritant test:
Multiple intact skin Irritation Test Method is selection body weight 20-25kg health white rabbit 3, and 24h will before experiment
The hair of white rabbit back backbone both sides is cut, the left and right each about 3cm*3cm of unhairing scope.Next day, eyelid will be sticked and alleviated regarding tired
The preparation stoste 0.5ml that sticks of labor is uniformly applied to side skin of unhairing surface, and opposite side skin of unhairing is as blank control.Apply
4h is smeared, residual tested material is removed with distilled water, smears once daily, continuously smear 14d, if necessary cropping, do not damage skin.
24h observations result after smearing every time;
Disposable damaged skin irritant test selection body weight 20-25kg health white rabbit 3,24h is by rabbit before experiment
The hair of back backbone both sides is cut, the left and right each about 3cm*3cm of unhairing scope.Next day, first sterilized with concentration for 75% alcohol wipe
Unhairing area skin, with the damaged wound of injection needle standardized " well " shape in dermatotome, 0.5ml is sticked into eyelid and alleviated regarding tired
The preparation stoste that sticks of labor is dripped on the 4 layers of gauze covered on damaged part skin, is then covered with one layer of oilpaper, then with stingless
Swash property immobilization with adhesive tape.Opposite side unhairing damaged skin is by the use of equivalent sterile purified water as control, with the same processing of preceding work.Application 4h
Afterwards, remove residual with distilled water and stick eyelid and alleviate visual fatigue and stick preparation stoste, after tested material is removed 1,24,
48h, observation local skin reaction.
The conclusion of two groups of skin irritation tests is:Skin irritation test result shows, sticks eyelid and alleviates visual fatigue
Stick preparation to the multiple irritant test rabbit epidermis of rabbit intact skin without significant change, be determined as nonirritant;To rabbit
The disposable irritant test of damaged skin, rabbit epidermis are determined as nonirritant without significant change.
The described preparation that sticks for sticking eyelid alleviation visual fatigue prepared by present embodiment carries out acute eye irritation test:
Take stick that eyelid alleviates visual fatigue to stick preparation 0.1ml, it is intracapsular to instill eye conjunctivas on the left of 3 rabbit, and another branch hole is to sterilize
Physiological saline is as control.After dripping tested material, eye is passively closed into 4s, rinsed after 30s with sterile saline.It is different after eye drip
Time visually observes damage and the recovery situation of rabbit eye conjunctiva, iris and cornea.
Acute eye irritation test result be stick eyelid alleviate visual fatigue stick preparation instill rabbit eyes after, 3 after 1h
The contamination branch hole conjunctiva congestion of blood vessel of rabbit and slight oedema, cornea and iris not damaged;Eye irritation reaction disappears completely in 72h
Lose, termination test.
Shown by 3 groups of experiments, stick low, the Small side effects that stick preparation excitant that eyelid alleviates visual fatigue.
Embodiment two:
The preparation method for sticking preparation that eyelid alleviation visual fatigue is sticked in present embodiment is carried out in the steps below:
Step 1, stick eyelid alleviate visual fatigue the parts by weight for sticking seed of feather cockscomb in preparation be 150 parts, the fruit of glossy privet
Parts by weight are 150 parts, and the parts by weight of cassia seed are 180 parts, and the parts by weight of pearl are 15 parts, the parts by weight of calcined and quenched CALAMINA
Number is 210 parts, and the parts by weight of grass-leaved sweetflag are 210 parts, and the parts by weight of peppermint are 240 parts, and the parts by weight of storax are 240
Part, the parts by weight of chrysanthemum are 300 parts, and the parts by weight of mulberry leaf are 300 parts, and the parts by weight of borneol are 10 parts, nipalgin second
The parts by weight of ester are 10 parts, and the parts by weight of cod-liver oil are 35 parts, and the parts by weight of animal bile are 35 parts, the weight of pure water
Measure number be 8000 parts, weigh respectively seed of feather cockscomb, the fruit of glossy privet, cassia seed, pearl, calcined and quenched CALAMINA, grass-leaved sweetflag, peppermint, storax,
Chrysanthemum, mulberry leaf, borneol, ethylparaben, cod-liver oil, animal bile, pure water, by load weighted pure water according to parts by weight
Be divided into three parts, by load weighted seed of feather cockscomb, the fruit of glossy privet, cassia seed, pearl, calcined and quenched CALAMINA, grass-leaved sweetflag, peppermint, storax,
Chrysanthemum, mulberry leaf are soaked in a pure water, soak time 2h, it is standby to obtain mixture A;
Step 2, the soaked mixture A of step 1 is carried out to boiling to boiling, after holding fluidized state 30min, by decoction
Extrusion, obtains concentrate A, use of separately purchasing, the dregs of a decoction is soaked in a pure water again, obtain mixture B;
Step 3, the mixture B for obtaining step 2 carry out boiling to boiling, and after keeping fluidized state 30min, decoction is squeezed
Go out, obtain concentrate B, use of separately purchasing, the dregs of a decoction are soaked in a pure water again, obtain mixture C;
Step 4, the mixture C for obtaining step 3 carry out boiling to boiling, and after keeping fluidized state 30min, decoction is squeezed
Go out, obtain concentrate C, concentrate A, concentrate B, concentrate C are mixed, obtain concentrating medicine after 300 mesh sieve net filtrations
Liquid;
Step 5, load weighted borneol, cod-liver oil, animal bile stirring added made from step 4 after concentrated medicament,
Load weighted ethylparaben is slowly added under conditions of stirring, stands 60min, the described eyelid that sticks is obtained and alleviates visual fatigue
To stick preparation stand-by;
Step 6, by non-woven fabrics be soaked in it is described stick that eyelid alleviates visual fatigue stick 2min in preparation, load afterwards
Seal, be made containing the described eye sticker for sticking preparation for sticking eyelid and alleviating visual fatigue in plastic-aluminum overlay film bag.
The preparation method for sticking preparation for sticking eyelid and alleviating visual fatigue described in present embodiment, described sticks eyelid
The working environment for alleviating the preparation method for sticking preparation of visual fatigue is 25 DEG C of room temperature, relative humidity 65%, clean rank 100,000
Level.
The preparation method for sticking preparation for sticking eyelid and alleviating visual fatigue described in present embodiment, non-woven fabrics in step 6
For rectangle non-woven fabrics, the length of non-woven fabrics is 6cm, width 3cm, thickness 0.05cm.
The preparation method for sticking preparation for sticking eyelid and alleviating visual fatigue described in present embodiment, non-woven fabrics in step 6
The preparation that sticks for sticking eyelid alleviation visual fatigue described in middle immersion is 2.2g.
Prepared by present embodiment sticks the eye sticker for sticking preparation that eyelid alleviates visual fatigue, present embodiment selection age
100 people in 15~65 years old, minimum 15 years old of patient age, maximum 65 years old, average age 43.66 ± 16.81 years old, with eye it is sleepy,
Photophobia, ache, shed tears, foreign body sensation, eye are dry and astringent, ophthalmospasm symptom visual fatigue patient with sympotoms, carry out sticking eyelid in lasting 10 days
Alleviate the eye sticker for sticking preparation of visual fatigue, patient will stick the eye sticker for sticking preparation of eyelid alleviation visual fatigue after closing one's eyes daily
It is affixed on eyes, every time 2 patch, 2 times a day, 15~20min every time.It is shown in Table 1 using patient symptom situation after 10 days:
Table 1 alleviates the eye sticker curative effect record sheet for sticking preparation of visual fatigue using eyelid is sticked
Prepared by present embodiment sticks the eye sticker for sticking preparation that eyelid alleviates visual fatigue, photophobia sleepy to eye, acid
Bitterly, shed tears, foreign body sensation, eye are dry and astringent, ophthalmospasm has obvious therapeutic effect.The cure rate 100% sleepy to eye, photophobia are controlled
More rate 88.2%, the cure rate 98% ached, the cure rate 93.3% shed tears, the cure rate 93.3% of foreign body sensation, eye is dry and astringent
Cure rate 97.9%, the cure rate 100% of ophthalmospasm.
Claims (8)
1. it is a kind of stick eyelid and alleviate visual fatigue stick preparation, it is characterised in that:The described eyelid that sticks alleviates visual fatigue
Preparation is sticked mainly by seed of feather cockscomb, the fruit of glossy privet, cassia seed, pearl, calcined and quenched CALAMINA, grass-leaved sweetflag, peppermint, storax, chrysanthemum, mulberry
Leaf, borneol, ethylparaben, cod-liver oil, animal bile, pure water are made, and its parts by weight is respectively 130~180 parts of green grass or young crops
Chest, 130~180 parts of the fruit of glossy privet, 150~200 parts of cassia seed, 10~20 parts of pearl, 200~250 parts of forge furnace are sweet
Stone, 200~250 parts of grass-leaved sweetflag, 230~270 parts of peppermint, 220~260 parts of storax, 250~350 parts of chrysanthemum,
250~350 parts of mulberry leaf, 10~20 parts of borneol, 10~20 parts of ethylparaben, 20~50 parts of cod-liver oil, 20~50
The animal bile, 7500~8500 parts of pure water of part.
2. it is according to claim 1 stick eyelid and alleviate visual fatigue stick preparation, it is characterised in that:Described sticks eye
The parts by weight for sticking seed of feather cockscomb in preparation that eyelid alleviates visual fatigue are 130 parts, and the parts by weight of the fruit of glossy privet are 130 parts, Cassia
The parts by weight of son are 150 parts, and the parts by weight of pearl are 10 parts, and the parts by weight of calcined and quenched CALAMINA are 200 parts, the weight of grass-leaved sweetflag
It is 200 parts to measure number, and the parts by weight of peppermint are 230 parts, and the parts by weight of storax are 220 parts, and the parts by weight of chrysanthemum are
250 parts, the parts by weight of mulberry leaf are 250 parts, and the parts by weight of borneol are 10 parts, and the parts by weight of ethylparaben are 10 parts,
The parts by weight of cod-liver oil are 20 parts, and the parts by weight of animal bile are 20 parts, and the parts by weight of pure water are 7500 parts.
3. it is according to claim 1 stick eyelid and alleviate visual fatigue stick preparation, it is characterised in that:Described sticks eye
The parts by weight for sticking seed of feather cockscomb in preparation that eyelid alleviates visual fatigue are 180 parts, and the parts by weight of the fruit of glossy privet are 180 parts, Cassia
The parts by weight of son are 200 parts, and the parts by weight of pearl are 20 parts, and the parts by weight of calcined and quenched CALAMINA are 250 parts, the weight of grass-leaved sweetflag
It is 250 parts to measure number, and the parts by weight of peppermint are 270 parts, and the parts by weight of storax are 260 parts, and the parts by weight of chrysanthemum are
350 parts, the parts by weight of mulberry leaf are 350 parts, and the parts by weight of borneol are 20 parts, and the parts by weight of ethylparaben are 20 parts,
The parts by weight of cod-liver oil are 50 parts, and the parts by weight of animal bile are 50 parts, and the parts by weight of pure water are 8500 parts.
4. it is according to claim 1 stick eyelid and alleviate visual fatigue stick preparation, it is characterised in that:Described sticks eye
The parts by weight for sticking seed of feather cockscomb in preparation that eyelid alleviates visual fatigue are 150 parts, and the parts by weight of the fruit of glossy privet are 150 parts, Cassia
The parts by weight of son are 180 parts, and the parts by weight of pearl are 15 parts, and the parts by weight of calcined and quenched CALAMINA are 210 parts, the weight of grass-leaved sweetflag
It is 210 parts to measure number, and the parts by weight of peppermint are 240 parts, and the parts by weight of storax are 240 parts, and the parts by weight of chrysanthemum are
300 parts, the parts by weight of mulberry leaf are 300 parts, and the parts by weight of borneol are 10 parts, and the parts by weight of ethylparaben are 10 parts,
The parts by weight of cod-liver oil are 35 parts, and the parts by weight of animal bile are 35 parts, and the parts by weight of pure water are 8000 parts.
5. the preparation method for sticking preparation for sticking eyelid and alleviating visual fatigue described in a kind of one of claim 1-4, its feature
It is:Comprise the following steps:
Step 1, seed of feather cockscomb, the fruit of glossy privet, cassia seed, pearl, calcined and quenched CALAMINA, the stone for weighing according to parts by weight certain mass respectively
Calamus, peppermint, storax, chrysanthemum, mulberry leaf, pure water, load weighted pure water is divided into three parts according to parts by weight, will
Load weighted seed of feather cockscomb, the fruit of glossy privet, cassia seed, pearl, calcined and quenched CALAMINA, grass-leaved sweetflag, peppermint, storax, chrysanthemum, mulberry leaf are soaked in
In a pure water, soak time 2h, it is standby to obtain mixture A;
Step 2, the soaked mixture A of step 1 is carried out to boiling to boiling, after holding fluidized state 30min, decoction squeezed
Go out, obtain concentrate A, use of separately purchasing, the dregs of a decoction are soaked in a pure water again, obtain mixture B;
Step 3, the mixture B for obtaining step 2 carry out boiling to boiling, after holding fluidized state 30min, by medical liquid squeezing,
Concentrate B is obtained, use of separately purchasing, the dregs of a decoction is soaked in a pure water again, obtain mixture C;
Step 4, the mixture C for obtaining step 3 carry out boiling to boiling, after holding fluidized state 30min, by medical liquid squeezing,
Concentrate C is obtained, concentrate A, concentrate B, concentrate C are mixed, concentrated medicament is obtained after 300 mesh sieve net filtrations;
Step 5, borneol, ethylparaben, cod-liver oil, the animal bile for weighing according to parts by weight certain mass respectively, will claim
After measured borneol, cod-liver oil, animal bile stirring add concentrated medicament made from step 4, slowly add under conditions of stirring
Enter load weighted ethylparaben, stand 30~60min, obtain the described preparation that sticks for sticking eyelid alleviation visual fatigue and treat
With;
Step 6, by non-woven fabrics be soaked in it is described stick that eyelid alleviates visual fatigue stick 1~3min in preparation, load afterwards
Seal, be made containing the described eye sticker for sticking preparation for sticking eyelid and alleviating visual fatigue in plastic-aluminum overlay film bag.
6. the preparation method according to claim 5 that stick preparation for sticking eyelid and alleviating visual fatigue, it is characterised in that:Institute
The working environment that states stick the preparation method for sticking preparation that eyelid alleviates visual fatigue is 18~26 DEG C of room temperature, relative humidity 45
~65%, clean 100,000 grades of rank.
7. the preparation method according to claim 5 that stick preparation for sticking eyelid and alleviating visual fatigue, it is characterised in that:Step
Non-woven fabrics is rectangle non-woven fabrics in rapid 6, and the length of non-woven fabrics is 5.5~6cm, and width is 2.5~3.5cm, thickness 0.05
~0.15cm.
8. the preparation method according to claim 5 that stick preparation for sticking eyelid and alleviating visual fatigue, it is characterised in that:Step
It is 1.8~2.2g to soak the described preparation that sticks for sticking eyelid alleviation visual fatigue in rapid 6 in non-woven fabrics.
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