CN109223919A - A kind of graphene precious jade medicine cover glass and preparation method thereof - Google Patents

A kind of graphene precious jade medicine cover glass and preparation method thereof Download PDF

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Publication number
CN109223919A
CN109223919A CN201811411488.1A CN201811411488A CN109223919A CN 109223919 A CN109223919 A CN 109223919A CN 201811411488 A CN201811411488 A CN 201811411488A CN 109223919 A CN109223919 A CN 109223919A
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weight
parts
graphene
cover glass
leaf
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赵立春
唐农
冷静
宋策
李俊秀
江婵玲
李玉凤
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Guangxi University of Chinese Medicine
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Guangxi University of Chinese Medicine
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/04Eye-masks ; Devices to be worn on the face, not intended for looking through; Eye-pads for sunbathing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/56Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638Ligustrum, e.g. Chinese privet
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    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/55Liquid-liquid separation; Phase separation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0635Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643Applicators, probes irradiating specific body areas in close proximity
    • A61N2005/0645Applicators worn by the patient
    • A61N2005/0647Applicators worn by the patient the applicator adapted to be worn on the head
    • AHUMAN NECESSITIES
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    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0659Radiation therapy using light characterised by the wavelength of light used infrared

Abstract

The present invention provides a kind of graphene precious jade medicine cover glasses and preparation method thereof, cover glass includes outer eyeshade and frenulum, outer eyeshade is divided into three layers, it is back sheet respectively, bulk pharmaceutical chemicals layer and heat conduction layer, bulk pharmaceutical chemicals are by following parts by weight material composition: climbing groundsel leaf 15-25 parts by weight, bajiao banana skin 5-10 parts by weight, dried peppermint leaf 5-10 parts by weight, fructus lycii 3-8 parts by weight, dandelion 3-8 parts by weight, chrysanthemum 1-5 parts by weight, honeysuckle 1-5 parts by weight, mulberry leaf 2-4 parts by weight, fruit of glossy privet 3-5 parts by weight, seed of feather cockscomb 1-3 parts by weight and butterflybush flower 2-5 parts by weight, far infrared can be launched by being provided between bulk pharmaceutical chemicals layer and back sheet, promote the graphene film material of eye microcirculation, using the principle of Chinese medicine meridian, the characteristic physical therapy efficacy of traditional precious jade medicine composition, in conjunction with graphene film What layer released is suitable for the far infrared progress physiotherapy that body absorbs, and can open eye peripheral point, dredge eye channels and collaterals, have and inhibit bacteria breed, restore improvement eye function, enhance the effect of ocular physiology function.

Description

A kind of graphene precious jade medicine cover glass and preparation method thereof
Technical field
The present invention relates to cover glass field, specially a kind of graphene precious jade medicine cover glass and preparation method thereof.
Background technique
With the development of China's economic and the progress of science and technology, the electronic products such as mobile phone, computer have come into everyone It lives, be unable to do without electronic product in more and more people's life.And the prolonged screen against electronic products such as computer, mobile phones The eye damage of people can be generated the symptoms such as visual fatigue, puckery, the near-sighted and long sight of eye again, cause the trouble of ocular pain The trend increased year by year is presented in person.
It is not only related with external environmental stimulus when there are the symptoms such as eye strain, pain, the own situation also with inherence Related, the remedy measures often taken for symptoms such as eye strain, myopia and amblyopias at present have is treated by eye drops, It has reached and alleviates eye strain, treatment myopia, the symptom of amblyopia, and eye drops is as common method for the treatment of, although in certain journey Alleviate the symptoms such as eye strain on degree, but the various chemical reagent wherein contained can also stimulate human eye, some patients due to To reagent allergy, the generation of side effect is also resulted in, and Chinese medicine thinks that the lesion of eye part is, liver blood closely related with whole body It is also the main reason for leading to eye symptom that deficiency, irascibility are partially high, and therefore, simple does not simply fail to radical cure closely using eye drops Depending on symptoms such as, long sights, alleviate eye strain, and have stimulated eyes to a certain extent, is not suitable for long-term use.
Therefore, how cover glass is improved, so that it is overcome disadvantages mentioned above again and can have the advantages that certain, is this field Technical staff's problem urgently to be resolved.
Summary of the invention
Graphene precious jade medicine cover glass is used the main purpose of the present invention is to provide a kind of, the characteristic of traditional precious jade medicine composition is managed Effect is treated, the far infrared that body absorbs that is suitable for released in conjunction with graphene film layer carries out physiotherapy, eye peripheral point is opened, Eye channels and collaterals are dredged, bacteria breed is inhibited, restores to improve eye function, enhances the effect of ocular physiology function.
To achieve the above objectives, the technical solution adopted by the present invention are as follows: a kind of graphene precious jade medicine cover glass, including outer eyeshade And frenulum, the outer eyeshade are divided into three layers, are back sheet, bulk pharmaceutical chemicals layer and heat conduction layer respectively, the bulk pharmaceutical chemicals are by following Parts by weight material composition: climbing groundsel leaf 15-25 parts by weight, bajiao banana skin 5-10 parts by weight, dried peppermint leaf 5-10 parts by weight, fructus lycii 3-8 Parts by weight, dandelion 3-8 parts by weight, chrysanthemum 1-5 parts by weight, honeysuckle 1-5 parts by weight, mulberry leaf 2-4 parts by weight, fruit of glossy privet 3-5 Parts by weight, seed of feather cockscomb 1-3 parts by weight and butterflybush flower 2-5 parts by weight, being provided between bulk pharmaceutical chemicals layer and back sheet can emit Out far infrared, promote eye microcirculation graphene film material.
As an improvement, the bulk pharmaceutical chemicals are by following parts by weight material composition: 20 parts by weight of climbing groundsel leaf, 8 weight of bajiao banana skin Part, 8 parts by weight of dried peppermint leaf, 6 parts by weight of fructus lycii, 6 parts by weight of dandelion, 3 parts by weight of chrysanthemum, 3 parts by weight of honeysuckle, 3 weight of mulberry leaf Measure part, 4 parts by weight of 4 parts by weight of the fruit of glossy privet, 2 parts by weight of seed of feather cockscomb and butterflybush flower.
As an improvement, the material that the back sheet uses is imitation velvet fabric.
As a further improvement, the back sheet is shading dark color fabric.
The second object of the present invention is to provide a kind of preparation method of graphene precious jade medicine cover glass, is included the following steps:
A kind of production method of graphene precious jade medicine cover glass, it is characterised in that: the following steps are included:
S1 weighs 20 parts by weight of climbing groundsel leaf, 8 parts by weight of bajiao banana skin, 6 parts by weight of fructus lycii, 6 weight of dandelion by formula The pure water of 200 parts by weight is added as in extractor altogether according to the proportion in part, 4 parts by weight of the fruit of glossy privet, 2 parts by weight of seed of feather cockscomb, It heating extraction 3-6 hours, is filtered with flame filter press, medical fluid is spare;
The pure water of 150 parts by weight is added into extractor again by S2, extracts 2-4 hours, is filtered with flame filter press, Filtered medical fluid merges with the medical fluid of first time filtration, discards the dregs of a decoction;
S3, it is 1.36-1.45 that the medicine liquid heating in S2, which is concentrated into specific gravity, and dehydrated alcohol is added after placing cooling, so that Medical fluid alcohol content is up to 35%, after mixing, is placed in return tank and is back to medical fluid without alcohol taste, heating is concentrated to give extractum A;
S4, by 8 parts by weight of dried peppermint leaf, 3 parts by weight of chrysanthemum, 3 parts by weight of honeysuckle, 3 parts by weight of mulberry leaf, 4 weight of butterflybush flower Part is co-located in extractor, and the ultrapure water of 80 parts by weight is added, heating extraction 2-4 hours, is filtered with flame filter press, medical fluid is standby With;
60 parts by weight pure water are added into S4 extractor, heating extraction 1-2 hours, are filtered with flame filter press, medicine by S5 Liquid merges with extracting solution in S4, discards filter residue, and heating is concentrated into paste, obtains medicinal extract B;
Extractum A and medicinal extract B are successively equably applied on the graphene film material of backing layer surface, it is small to dry 4-6 by S6 When, 60-80 DEG C dries 2 hours, encapsulates to get graphene precious jade medicine cover glass.
Preferably, thickening temperature is cooled to room temperature after being 80-100 DEG C, 6-8 hours in S3.
Preferably, after extractum A and medicinal extract B are successively equably applied to the graphene film material of backing layer surface in S5, in It is dried in baking oven, temperature is set as 70 DEG C in baking oven.
Beneficial effects of the present invention are as follows:
Graphene precious jade medicine cover glass provided by the invention, by using traditional national precious jade medicine composition, from treating both manifestation and root cause of disease Angle is set out, and using climbing groundsel leaf, bajiao banana skin and dried peppermint leaf as main ingredient, climbing groundsel leaf is cold in nature, has clearing heat and detoxicating, improving eyesight The effect of, bajiao banana skin smell is sweet, Great Cold, there is clearing heat and detoxicating effect, and dried peppermint leaf taste is refrigerant, the mutual compatibility of three is not only It can clear liver and improve vision, effectively inhibit the growth of eye bacterium, prevent ocular infection, meanwhile, refrigerant smell can cover tradition The taste of Chinese medicine so that more salubrious comfortable when using, also include in bulk pharmaceutical chemicals fructus lycii, the fruit of glossy privet, dandelion, chrysanthemum, Honeysuckle, mulberry leaf, the fruit of glossy privet, seed of feather cockscomb and butterflybush flower cooperate as auxiliary medicinal material, main ingredient and adjuvant, have evacuation wind The effect of heat, head clearing, wind-expelling pain-stopping, blood-activating and qi-promoting, can not only loosen eye muscle, and fundamentally alleviates and bring Graphene film material, when taking eyeshade, graphene film layer is arranged in the reason of eye strain between bulk pharmaceutical chemicals layer and back sheet The far infrared absorbed suitable for body can be launched, promote eye microcirculation, optimal stimulation is carried out on eye peripheral point and arrive and pass through Network has adjusted the balance of maincenter and nervous system, and far infrared further suppresses the nourishing of bacterium, keeps eye cleaning, accelerates The transmitting of bulk pharmaceutical chemicals promotes effective ingredient to absorb by body capillary rapid osmotic to circumference of eyes tissue and quickly, It complements each other, reaches equilibrium between yin and yang, and then eyesight is stablized or improved.
Detailed description of the invention
Fig. 1 is graphene precious jade medicine cover glass preparation method flow chart.
Specific embodiment
It is described below for disclosing the present invention so that those skilled in the art can be realized the present invention.It is excellent in being described below Embodiment is selected to be only used as illustrating, it may occur to persons skilled in the art that other obvious modifications.
Preparation method embodiment 1:
Formula:
20 parts by weight of climbing groundsel leaf, 8 parts by weight of bajiao banana skin, 8 parts by weight of dried peppermint leaf, 6 parts by weight of fructus lycii, 6 weight of dandelion Part, 3 parts by weight of chrysanthemum, 3 parts by weight of honeysuckle, 3 parts by weight of mulberry leaf, 4 parts by weight of the fruit of glossy privet, 2 parts by weight of seed of feather cockscomb and close illiteracy Spend 4 parts by weight.
Preparation process:
S1 weighs 20 parts by weight of climbing groundsel leaf, 8 parts by weight of bajiao banana skin, 6 parts by weight of fructus lycii, 6 weight of dandelion by formula The pure water of 200 parts by weight is added as in extractor altogether according to the proportion in part, 4 parts by weight of the fruit of glossy privet, 2 parts by weight of seed of feather cockscomb, It heating extraction 3-6 hours, is filtered with flame filter press, medical fluid is spare;
The pure water of 150 parts by weight is added into extractor again by S2, extracts 2-4 hours, is filtered with flame filter press, Filtered medical fluid merges with the medical fluid of first time filtration, discards the dregs of a decoction;
S3, it is 1.36-1.45 that the medicine liquid heating in S2, which is concentrated into specific gravity, and dehydrated alcohol is added after placing cooling, so that Medical fluid alcohol content is up to 35%, after mixing, is placed in return tank and is back to medical fluid without alcohol taste, heating is concentrated to give extractum A;
S4, by 8 parts by weight of dried peppermint leaf, 3 parts by weight of chrysanthemum, 3 parts by weight of honeysuckle, 3 parts by weight of mulberry leaf, 4 weight of butterflybush flower Part is co-located in extractor, and the ultrapure water of 80 parts by weight is added, heating extraction 2-4 hours, is filtered with flame filter press, medical fluid is standby With;
60 parts by weight pure water are added into S4 extractor, heating extraction 1-2 hours, are filtered with flame filter press, medicine by S5 Liquid merges with extracting solution in S4, discards filter residue, and heating is concentrated into paste, obtains medicinal extract B;
Extractum A and medicinal extract B are successively equably applied on the graphene film material of backing layer surface, it is small to dry 4-6 by S6 When, 60-80 DEG C dries 2 hours, encapsulates to get graphene precious jade medicine cover glass.
Preparation method embodiment 2:
Formula:
15 parts by weight of climbing groundsel leaf, 5 parts by weight of bajiao banana skin, 5 parts by weight of dried peppermint leaf, 3 parts by weight of fructus lycii, 3 weight of dandelion Part, 1 parts by weight of chrysanthemum, 1 parts by weight of honeysuckle, 2 parts by weight of mulberry leaf, 3 parts by weight of the fruit of glossy privet, 1 parts by weight of seed of feather cockscomb and close illiteracy Spend 2 parts by weight.
Preparation process:
S1 weighs 15 parts by weight of climbing groundsel leaf, 5 parts by weight of bajiao banana skin, 3 parts by weight of fructus lycii, 3 weight of dandelion by formula The pure water of 200 parts by weight is added as in extractor altogether according to the proportion in part, 3 parts by weight of the fruit of glossy privet, 1 parts by weight of seed of feather cockscomb, It heating extraction 3-6 hours, is filtered with flame filter press, medical fluid is spare;
The pure water of 150 parts by weight is added into extractor again by S2, extracts 2-4 hours, is filtered with flame filter press, Filtered medical fluid merges with the medical fluid of first time filtration, discards the dregs of a decoction;
S3, it is 1.36-1.45 that the medicine liquid heating in S2, which is concentrated into specific gravity, and dehydrated alcohol is added after placing cooling, so that Medical fluid alcohol content is up to 35%, after mixing, is placed in return tank and is back to medical fluid without alcohol taste, heating is concentrated to give extractum A;
S4, by 5 parts by weight of dried peppermint leaf, 1 parts by weight of chrysanthemum, 1 parts by weight of honeysuckle, 2 parts by weight of mulberry leaf, 2 weight of butterflybush flower Part is co-located in extractor, and the ultrapure water of 80 parts by weight is added, heating extraction 2-4 hours, is filtered with flame filter press, medical fluid is standby With;
60 parts by weight pure water are added into S4 extractor, heating extraction 1-2 hours, are filtered with flame filter press, medicine by S5 Liquid merges with extracting solution in S4, discards filter residue, and heating is concentrated into paste, obtains medicinal extract B;
Extractum A and medicinal extract B are successively equably applied on the graphene film material of backing layer surface, it is small to dry 4-6 by S6 When, 60-80 DEG C dries 2 hours, encapsulates to get graphene precious jade medicine cover glass.
Preparation method embodiment 3:
Formula:
25 parts by weight of climbing groundsel leaf, 10 parts by weight of bajiao banana skin, 10 parts by weight of dried peppermint leaf, 8 parts by weight of fructus lycii, 8 weight of dandelion Measure part, 5 parts by weight of chrysanthemum, 5 parts by weight of honeysuckle, 4 parts by weight of mulberry leaf, 5 parts by weight of the fruit of glossy privet, 3 parts by weight of seed of feather cockscomb and close Illiteracy spends 5 parts by weight.
Preparation process:
S1 weighs 25 parts by weight of climbing groundsel leaf, 10 parts by weight of bajiao banana skin, 8 parts by weight of fructus lycii, 8 weight of dandelion by formula The pure water of 200 parts by weight is added as in extractor altogether according to the proportion in part, 5 parts by weight of the fruit of glossy privet, 3 parts by weight of seed of feather cockscomb, It heating extraction 3-6 hours, is filtered with flame filter press, medical fluid is spare;
The pure water of 150 parts by weight is added into extractor again by S2, extracts 2-4 hours, is filtered with flame filter press, Filtered medical fluid merges with the medical fluid of first time filtration, discards the dregs of a decoction;
S3, it is 1.36-1.45 that the medicine liquid heating in S2, which is concentrated into specific gravity, and dehydrated alcohol is added after placing cooling, so that Medical fluid alcohol content is up to 35%, after mixing, is placed in return tank and is back to medical fluid without alcohol taste, heating is concentrated to give extractum A;
S4, by 10 parts by weight of dried peppermint leaf, 5 parts by weight of chrysanthemum, 5 parts by weight of honeysuckle, 4 parts by weight of mulberry leaf, 5 weight of butterflybush flower Part is co-located in extractor, and the ultrapure water of 80 parts by weight is added, heating extraction 2-4 hours, is filtered with flame filter press, medical fluid is standby With;
60 parts by weight pure water are added into S4 extractor, heating extraction 1-2 hours, are filtered with flame filter press, medicine by S5 Liquid merges with extracting solution in S4, discards filter residue, and heating is concentrated into paste, obtains medicinal extract B;
Extractum A and medicinal extract B are successively equably applied on the graphene film material of backing layer surface, it is small to dry 4-6 by S6 When, 60-80 DEG C dries 2 hours, encapsulates to get graphene precious jade medicine cover glass.
Preparation method embodiment 4:
Formula:
23 parts by weight of climbing groundsel leaf, 8 parts by weight of bajiao banana skin, 8 parts by weight of dried peppermint leaf, 6 parts by weight of fructus lycii, 7 weight of dandelion Part, 4 parts by weight of chrysanthemum, 4 parts by weight of honeysuckle, 3 parts by weight of mulberry leaf, 5 parts by weight of the fruit of glossy privet, 2 parts by weight of seed of feather cockscomb and close illiteracy Spend 4 parts by weight.
Preparation process:
S1 weighs 23 parts by weight of climbing groundsel leaf, 8 parts by weight of bajiao banana skin, 6 parts by weight of fructus lycii, 7 weight of dandelion by formula The pure water of 200 parts by weight is added as in extractor altogether according to the proportion in part, 5 parts by weight of the fruit of glossy privet, 2 parts by weight of seed of feather cockscomb, It heating extraction 3-6 hours, is filtered with flame filter press, medical fluid is spare;
The pure water of 150 parts by weight is added into extractor again by S2, extracts 2-4 hours, is filtered with flame filter press, Filtered medical fluid merges with the medical fluid of first time filtration, discards the dregs of a decoction;
S3, it is 1.36-1.45 that the medicine liquid heating in S2, which is concentrated into specific gravity, and dehydrated alcohol is added after placing cooling, so that Medical fluid alcohol content is up to 35%, after mixing, is placed in return tank and is back to medical fluid without alcohol taste, heating is concentrated to give extractum A;
S4, by 8 parts by weight of dried peppermint leaf, 4 parts by weight of chrysanthemum, 4 parts by weight of honeysuckle, 3 parts by weight of mulberry leaf, 4 weight of butterflybush flower Part is co-located in extractor, and the ultrapure water of 80 parts by weight is added, heating extraction 2-4 hours, is filtered with flame filter press, medical fluid is standby With;
60 parts by weight pure water are added into S4 extractor, heating extraction 1-2 hours, are filtered with flame filter press, medicine by S5 Liquid merges with extracting solution in S4, discards filter residue, and heating is concentrated into paste, obtains medicinal extract B;
Extractum A and medicinal extract B are successively equably applied on the graphene film material of backing layer surface, it is small to dry 4-6 by S5 When, 60-80 DEG C dries 2 hours, encapsulates to get graphene precious jade medicine cover glass.
Preparation method embodiment 5:
Formula:
20 parts by weight of climbing groundsel leaf, 8 parts by weight of bajiao banana skin, 8 parts by weight of dried peppermint leaf, 6 parts by weight of fructus lycii, 6 weight of dandelion Part, 3 parts by weight of chrysanthemum, 3 parts by weight of honeysuckle, 3 parts by weight of mulberry leaf, 4 parts by weight of the fruit of glossy privet, 2 parts by weight of seed of feather cockscomb and close illiteracy Spend 4 parts by weight.
Preparation process:
S1 weighs 20 parts by weight of climbing groundsel leaf, 8 parts by weight of bajiao banana skin, 6 parts by weight of fructus lycii, 6 weight of dandelion by formula The pure water of 200 parts by weight is added as in extractor altogether according to the proportion in part, 4 parts by weight of the fruit of glossy privet, 2 parts by weight of seed of feather cockscomb, It heating extraction 3-6 hours, is filtered with flame filter press, medical fluid is spare;
The pure water of 150 parts by weight is added into extractor again by S2, extracts 2-4 hours, is filtered with flame filter press, Filtered medical fluid merges with the medical fluid of first time filtration, discards the dregs of a decoction;
S3, it is 1.36-1.45 that the medicine liquid heating in S2, which is concentrated into specific gravity, and dehydrated alcohol is added after placing cooling, so that Medical fluid alcohol content is up to 35%, after mixing, is placed in return tank and is back to medical fluid without alcohol taste, heating is concentrated to give extractum A;
S4, by 8 parts by weight of dried peppermint leaf, 3 parts by weight of chrysanthemum, 3 parts by weight of honeysuckle, 3 parts by weight of mulberry leaf, 4 weight of butterflybush flower Part is co-located in extractor, and the ultrapure water of 80 parts by weight is added, heating extraction 2-4 hours, is filtered with flame filter press, medical fluid is standby With;
60 parts by weight pure water are added into S4 extractor, heating extraction 1-2 hours, are filtered with flame filter press, medicine by S5 Liquid merges with extracting solution in S4, discards filter residue, and heating is concentrated into paste, obtains medicinal extract B;
Extractum A and medicinal extract B are successively equably applied on the surface of the back sheet not comprising graphene film material by S5, It dries 4-6 hours, 60-80 DEG C dries 2 hours, encapsulates to get the common precious jade medicine cover glass of graphene film material is not included.
Test example 1:
It is not wrapped with the preparation method embodiment 1-4 of the invention graphene precious jade medicine cover glass being prepared and embodiment 5 The common precious jade medicine cover glass of containing graphene film layer be experimental group, use common cover glass as control group, observation experiment group with The antibacterial situation of control group, using healthy rabbits, male and female, hair color is regardless of, and 1.5-2 kilograms of weight.
Strain inoculation method: first with 0.5% dicaine make anterior corneal surface anesthesia it is secondary, by 3,000,000/milliliter Pseudomonas aeruginosas About 0.01 milliliter of bacterium solution, injection cornea essence shallow-layer, make about 3 × 3 millimeter 2 of focal zone.
For each cover glass that table 1 shows, 50 rabbit are chosen, each one cover glass, every 6 × 8 milli of agreement that contracts a film or TV play to an actor or actress Rice 2, is attached to lesion and goes by about 0.2 milligram of content of dispersion, and 2 times a day, inoculation takes secretion to make bacterium training with " flat band method " after 24 hours It supports, checked that once until turning out cloudy for the second time, Bacteria Culture situation was as shown in table 1 every three days later:
Table 1: test example
As can be seen from the above table, it is statistically analyzed, embodiment 1-4, common precious jade medicine cover glass group and control group Meaning that there was a significant difference (P < 0.01) illustrates effectively inhibit bacterium using graphene film layer and the mutual cooperation of bulk pharmaceutical chemicals layer It breeds, helps to maintain the cleaning of eye, accelerate the recovery situation of ocular infection.
Test example 2
This test example for investigate embodiment 1, the common cover glass not comprising graphene film layer and it is commercially available value it is bright The clinical trial effect of eye drops.
This test example selects low myopia Patients with 300 Cases using random, contrast clinical trial altogether, using simple randomization method, fortune Uniformly go out table of random number with SAS software, is randomly divided into experimental group, common cover glass group and ZHENSHIMING DIYANYE group, every group 100 A nearsighted persons, no matter gender, age, each group treatment time is 3 courses for the treatment of, and experimental group and common cover glass group use 1 Times/day, 1 30min proposes a course for the treatment of for 7 days, and 3 courses for the treatment of are a cycle;ZHENSHIMING DIYANYE group, dripping eyedrop, 1 drop/time, 4 times a day, 7 days as a course for the treatment of, and 3 courses for the treatment of are a cycle, and treatment results are as shown in table 2:
Table 2:
Wherein, it fully recovers: uncorrected visual acuity >=1.0;Effective: eyesight improves (logarithmic visual acuity chart) 3 row (containing) or more, but is not achieved 1.0;Improve: eyesight improves (logarithmic visual acuity chart) 1~2 row, but is not achieved 1.0;It is invalid: exclude other diseases interference, eyesight compared with Decline before treatment.
Cross the randomized control study to Chinese medicine heat therapy eyeshade, simple Traditional Chinese medicine eyeshade and ZHENSHIMING DIYANYE to low myopia eye Show that, to 3 course of therapy of low myopia eye, graphene precious jade medicine cover glass and common precious jade medicine cover glass curative effect are superior to value The curative effect of bright eye drops, graphene precious jade medicine cover glass is better than common precious jade medicine cover glass curative effect, shows graphene precious jade medicine cover glass There is preferable effect in clinical treatment low myopia.
The basic principles, main features and advantages of the present invention have been shown and described above.The technology of the industry Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and what is described in the above embodiment and the description is only the present invention Principle, various changes and improvements may be made to the invention without departing from the spirit and scope of the present invention, these variation and Improvement is both fallen in the range of claimed invention.The present invention claims protection scope by appended claims and its Equivalent defines.

Claims (8)

1. a kind of graphene precious jade medicine cover glass, including outer eyeshade and frenulum, the outer eyeshade are divided into three layers, be respectively back sheet, Bulk pharmaceutical chemicals layer and heat conduction layer, it is characterised in that: the bulk pharmaceutical chemicals are by following parts by weight material composition: climbing groundsel leaf 15-25 Parts by weight, bajiao banana skin 5-10 parts by weight, dried peppermint leaf 5-10 parts by weight, fructus lycii 3-8 parts by weight, dandelion 3-8 parts by weight, chrysanthemum 1- 5 parts by weight, honeysuckle 1-5 parts by weight, mulberry leaf 2-4 parts by weight, fruit of glossy privet 3-5 parts by weight, seed of feather cockscomb 1-3 parts by weight and close illiteracy Flower 2-5 parts by weight are provided with the graphite that can launch far infrared, promote eye microcirculation between bulk pharmaceutical chemicals layer and back sheet Alkene membrane material.
2. graphene precious jade medicine cover glass according to claim 1, it is characterised in that: the bulk pharmaceutical chemicals are by following parts by weight object Matter composition: 20 parts by weight of climbing groundsel leaf, 8 parts by weight of bajiao banana skin, 8 parts by weight of dried peppermint leaf, 6 parts by weight of fructus lycii, 6 weight of dandelion Part, 3 parts by weight of chrysanthemum, 3 parts by weight of honeysuckle, 3 parts by weight of mulberry leaf, 4 parts by weight of the fruit of glossy privet, 2 parts by weight of seed of feather cockscomb and close illiteracy Spend 4 parts by weight.
3. graphene precious jade medicine cover glass according to claim 1 to 2, it is characterised in that: the material that the back sheet uses Material is imitation velvet fabric.
4. graphene precious jade medicine cover glass according to claim 3, it is characterised in that: the back sheet is shading dark color face Material.
5. graphene precious jade medicine cover glass according to claim 1, it is characterised in that: the bulk pharmaceutical chemicals are particle, tablet, powder One of agent.
6. a kind of production method of graphene precious jade medicine cover glass, it is characterised in that: the following steps are included:
S1 weighs 20 parts by weight of climbing groundsel leaf, 8 parts by weight of bajiao banana skin, 6 parts by weight of fructus lycii, 6 parts by weight of dandelion, female by formula Loyal son 4 parts by weight, 2 parts by weight of seed of feather cockscomb, are added the pure water of 200 parts by weight as in extractor altogether according to the proportion, heating mentions It takes 3-6 hours, is filtered with flame filter press, medical fluid is spare;
The pure water of 150 parts by weight is added into extractor again by S2, extracts 2-4 hours, is filtered with flame filter press, filters Medical fluid afterwards merges with the medical fluid of first time filtration, discards the dregs of a decoction;
S3, it is 1.36-1.45 that the medicine liquid heating in S2, which is concentrated into specific gravity, dehydrated alcohol is added after placing cooling, so that medical fluid Alcohol content is up to 35%, after mixing, is placed in return tank and is back to medical fluid without alcohol taste, heating is concentrated to give extractum A;
8 parts by weight of dried peppermint leaf, 3 parts by weight of chrysanthemum, 3 parts by weight of honeysuckle, 3 parts by weight of mulberry leaf, 4 parts by weight of butterflybush flower are total to by S4 It is placed in extractor, the ultrapure water of 80 parts by weight is added, heating extraction 2-4 hours, is filtered with flame filter press, medical fluid is spare;
60 parts by weight pure water are added into S4 extractor, heating extraction 1-2 hours, are filtered with flame filter press by S5, medical fluid with Extracting solution merges in S4, discards filter residue, and heating is concentrated into paste, obtains medicinal extract B;
Extractum A and medicinal extract B are successively equably applied on the graphene film material of backing layer surface by S6, are dried 4-6 hours, 60-80 DEG C dries 2 hours, encapsulates to get graphene precious jade medicine cover glass.
7. the production method that graphene according to claim 6 warms up precious jade medicine cover glass, it is characterised in that: thickening temperature in S3 It is 80-100 DEG C, is cooled to room temperature after 6-8 hours.
8. graphene according to claim 7 warm up precious jade medicine cover glass production method, it is characterised in that: in S6 extractum A and After medicinal extract B is successively equably applied to the graphene film material of backing layer surface, dried in baking oven, temperature is set as in baking oven 70℃。
CN201811411488.1A 2018-11-24 2018-11-24 A kind of graphene precious jade medicine cover glass and preparation method thereof Pending CN109223919A (en)

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Application publication date: 20190118