CN104258295A - Traditional Chinese medicine decoction for treating lymphoma - Google Patents

Traditional Chinese medicine decoction for treating lymphoma Download PDF

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Publication number
CN104258295A
CN104258295A CN201410537949.5A CN201410537949A CN104258295A CN 104258295 A CN104258295 A CN 104258295A CN 201410537949 A CN201410537949 A CN 201410537949A CN 104258295 A CN104258295 A CN 104258295A
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lymphoma
chinese medicine
decoction
traditional chinese
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王文玲
张敏丽
逄瑞莲
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536Prunella or Brunella (selfheal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • A61K36/03Phaeophycota or phaeophyta (brown algae), e.g. Fucus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/483Gleditsia (locust)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/808Scrophularia (figwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/902Sparganiaceae (Bur-reed family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
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Abstract

The invention relates to the technical field of traditional Chinese medicines, particularly to a traditional Chinese medicine decoction for treating the lymphoma. The decoction is prepared from bulk drugs by weight as follows: 20 g of common selfheal fruit-spike, 20 g of oyster shell, 30 g of milkvetch root, 15 g of catclaw buttercup root, 15 g of alga, 12 g of common burreed tuber, 12 g of curcumae rhizoma, 10 g of forsythia suspensa, 10 g of scrophularia, 10 g of poria cocos, 10 g of bombyx batryticatus, 10 g of Chinese honeylocust spine and 10 g of cassia twig. The decoction has effects of removing stasis, diminishing swelling, removing toxins, alleviating pain, invigorating qi, strengthening superficies, clearing away heat, purging pathogenic fire, eliminating pernicious influence, outthrusting pus, warming meridians and freeing vessels, is convenient to use, good in absorbing effect and free of adverse, toxic and side effects, and has very good relief and treatment effects on the lymphoma.

Description

One treats lymphadenomatous Chinese medicine decoction
Technical field
The present invention relates to the technical field of Chinese medicine, specifically one treats lymphadenomatous Chinese medicine decoction.
Background technology
Lymphoma is the malignant tumor originating from lymphohematological, and main manifestations is Silent Neuritis lymphadenectasis, hepatosplenomegaly, and each histoorgan of whole body all can be got involved, the heat that occurs together, night sweat, become thin, the General Symptoms such as pruritus.According to " World Health Organization's lymphsystem tumor pathological classification standard ", current known lymphoma has nearly 70 kinds of histological type, substantially can be divided into Hodgkin lymphoma and the large class of non-Hodgkin lymphoma two.In China, Hodgkin lymphoma accounts for lymphadenomatous 9% ~ 10%, is one group of curative effect malignant tumor relatively preferably; Non-Hodgkin lymphoma accounts for about 90% of whole lymphom case, and sickness rate raises year by year in recent ten years.
At present, lymphadenomatous Therapeutic Method mainly contains radiotherapy, chemotherapy, bone marrow transplantation and operative treatment.Although it is a lot of to treat lymphadenomatous medicine, but less effective, especially for old people, because body constitution is weak, immunity is low, as can the stagnation of QI be caused without suitably treating, blood stasis, food is poly-, a series of pathological changes such as evil poison gathering, therefore the necessary safety of lymphadenomatous medicine is treated, effectively, have no side effect, and Chinese materia medica is as the traditional medicine of China, there is effect strong, instant effect, the advantages such as lasting medicine, and there is no dependency, drug resistance and toxic and side effects, therefore a kind of Chinese medicine preparation is selected to treat lymphoma, for treatment lymphoma, there is very important clinical meaning.
Summary of the invention
The present invention is directed to the deficiencies in the prior art, according to theory of Chinese medical science, by drug screening and the clinical verification repeatedly of several years, provide one to treat lymphadenomatous Chinese medicine decoction, have fabulous alleviation and therapeutic effect to lymphoma.
The technical solution used in the present invention is: one treats lymphadenomatous Chinese medicine decoction, and it is made up of the material medicine of following weight proportion: Spica Prunellae 20 grams, Concha Ostreae 20 grams, the Radix Astragali 30 grams, Radix Ranunculi Ternati 15 grams, Sargassum 15 grams, Rhizoma Sparganii 12 grams, Rhizoma Curcumae 12 grams, Fructus Forsythiae 10 grams, Radix Scrophulariae 10 grams, 10 grams, Poria, Bombyx Batryticatus 10 grams, Spina Gleditsiae 10 grams, Ramulus Cinnamomi 10 grams.
Get material medicine of the present invention, after conventional Preparation process, add water and do not have powder 2 centimetres to be advisable, soak 30 minutes, head is decocted and is often paid medicine and decoct to 100ml.Two decoct the 300ml that adds water again, decoct to 100ml, decoct to each get two 100ml and be mixed and take.Every day one pair, every twice-daily, early, take evening, each 100ml 10th was 1 course for the treatment of.
Spica Prunellae in the present invention: bitter in the mouth, pungent, cold in nature; Return liver, gallbladder meridian; There is effect of liver heat removing and eyesight improving, clearing away heat and promoting diuresis, mass dissipating and swelling eliminating.Concha Ostreae: salty in the mouth, cold nature; Return liver, gallbladder, kidney channel; Have convergence calm, removing toxic substances analgesia, suppressing the hyperactive liver and subsiding YANG, tranquillizing the mind by relieving convulsion, hard masses softening and resolving, restrains astringent or styptic treatment for spontaneous sweating effect.The Radix Astragali: sweet in the mouth, slightly warm in nature; Return lung, spleen, liver, kidney channel; There is invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, effect of expelling pus and promoting granulation.Radix Ranunculi Ternati: sweet in the mouth, pungent, warm in nature, slightly poisonous; Return Liver Channel, lung meridian; There is eliminating stagnation, effect of detumescence; , pulmonary tuberculosis, tuberculous lymphadenitis, lymphadenitis, pharyngolaryngitis not routed for scrofula, tuberculous lymphadenitis.Sargassum: bitter in the mouth, salty, cold in nature; Enter lung, spleen, kidney, liver stomach warp; There is softening the hard mass, expectorant, diuretic, detumescent, effect of heat clearing away, hard masses softening and resolving.Rhizoma Sparganii: bitter in the mouth, property is put down; There is removing blood stasis, circulation of qi promoting, effect of removing food stagnancy pain relieving.Rhizoma Curcumae: acrid in the mouth, hardship, warm in nature; Return liver, spleen channel; There is circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving, promoting the circulation of QI to relieve pain, removing blood stasis removing food stagnancy, effect of promoting digestion and removing stagnation.Fructus Forsythiae: bitter in the mouth, cold nature; There is heat-clearing and toxic substances removing, dispelling wind and heat pathogens, effect of mass dissipating and swelling eliminating.Radix Scrophulariae: bitter in the mouth, salty, cold nature is nontoxic; There is yin nourishing removing heat from blood, clearing away heat-fire, relieving restlessness quenched the thirst, effect of detoxicating and resolving stagnation of pathogens.Poria: sweet in the mouth, light, property is put down; GUIXIN warp, lung meridian, spleen channel, kidney channel; There is effect of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Bombyx Batryticatus: salty in the mouth, pungent, property is put down; Return liver, lung, stomach warp; There is expelling wind for relieving convulsion, effect of dissipating phlegm and resolving masses.Spina Gleditsiae: acrid in the mouth, warm in nature; Return liver, lung meridian; There is the saturating pus of sterilization, search wind, effect of parasite killing; Cure mainly swollen ulcer drug, scrofula, skin ulcer rash stubborn dermatitis, puerperal hypogalactia, placenta retention, leprosy.Ramulus Cinnamomi: acrid in the mouth, sweet, warm in nature; GUIXIN, lung, urinary bladder channel; There is effect of diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain.
The invention has the beneficial effects as follows that cost is low, taking convenience, there is effect of mass dissipating and swelling eliminating, removing toxic substances analgesia, invigorating QI to consolidate the body surface resistance, clearing away heat-fire, the saturating pus of sterilization, warming the meridian and promoting blood circulation, easy to use, good absorbing effect, without bad and toxic and side effects, has fabulous alleviation and therapeutic effect to lymphoma.
Detailed description of the invention:
Embodiment 1: one treats lymphadenomatous Chinese medicine decoction, it is made up of the crude drug of following weight proportion: Spica Prunellae 20 grams, Concha Ostreae 20 grams, the Radix Astragali 30 grams, Radix Ranunculi Ternati 15 grams, Sargassum 15 grams, Rhizoma Sparganii 12 grams, Rhizoma Curcumae 12 grams, Fructus Forsythiae 10 grams, Radix Scrophulariae 10 grams, 10 grams, Poria, Bombyx Batryticatus 10 grams, Spina Gleditsiae 10 grams, Ramulus Cinnamomi 10 grams.
One is treated lymphadenomatous Chinese medicine decoction clinical efficacy and is summed up:
One, clinical data: select the routine clinical observation of Lymphoma 150 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 75 example, wherein male 40 example, women 35 example, 35 ~ 75 years old age, 55 years old mean age, the course of disease 1 ~ 20 year; Matched group 75 example, wherein male 42 example, women 34 example, 34 ~ 74 years old age, 54 years old mean age, the course of disease 1 ~ 18 year.The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
Two, Therapeutic Method: treatment group takes medicine of the present invention, with being decocted in water for oral dose, every day 1 dose, 2 sub-services; Within 7 days, be 1 course for the treatment of, 3 ~ 4 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.Matched group takes methotrexate, oral, a 5mg-10mg (2-4 sheet) of being grown up, 1 time on the one, 1-2 time weekly, a safe dose 50mg-100mg course for the treatment of (20--40 sheet).
Three, therapeutic evaluation:
Observe the x-ray performance bone texture of position of disease in the 1-2 month tiny or interrupt, femoral head cyst, sclerosis, flat or subside, the change before and after the symptom treatment such as pain, ankylosis.
Cure: lump disappears, symptom and sign disappears, and immunity strengthens, and does not recur after drug withdrawal.
Effective: lump obviously reduces, symptom and sign is obviously alleviated, and recurs lighter after drug withdrawal.
Effective: lump reduces to some extent, symptom and sign partial rcsponse, recurs after drug withdrawal to some extent.
Invalid: after treatment, clinical symptoms is without improvement, or has the trend of deterioration.
Four, therapeutic effect: use the present invention to treat 75 examples, result cures 64 examples, effective 6 examples, effective 2 examples, invalid 3 examples, total effective rate is 96%.
Five, model case
1, Wang, man, 55 years old, the prolonged low grade fever of patient's unknown cause, often itch with skin, hyperhidrosis, to become thin and symptom such as superficial lymph knot enlargement etc., once took various medicine, effect was all not obvious, and my institute checks afterwards, is diagnosed as lymphoma.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, symptom takes a turn for the better, and after continuing to take 3 courses for the treatment of, transference cure, body temperature is normal, and immunity strengthens.
2, Feng, female, 70 years old, originally patient have a fever, feel suffocated, uncomfortable in chest, there is no appetite, once suffer from super-dry syndrome.My institute checked afterwards, and find chlamydia, mycoplasma infection, peritoneum has lump, lymphadenectasis, and hepatosplenomegaly is diagnosed as lymphoma.After taking 3 courses for the treatment of of Chinese medicine preparation of the present invention, the symptoms such as peritoneum lump, lymph enlargement are obviously alleviated, and continue to take 2 courses for the treatment of, and lymphatic function recovers, and laboratory indexes is all normal.Follow up a case by regular visits to and do not recur so far.
3, in certain, female, 45 years old, the enlargement of patient's cervical lymph node, and, rapid breathing, body weight more than with cough baffledly alleviate, the frequent symptom such as low grade fever, excessive perspiration, especially at night, night sweat is very serious, once took various detumescence, cough suppressing medicine etc., effect is all not obvious, and my institute was diagnosed as lymphoma afterwards.After taking 3 courses for the treatment of of Chinese medicine preparation of the present invention, symptom takes a turn for the better, and after continuing to take 2 courses for the treatment of, transference cure, breathes smooth and easy.Follow up a case by regular visits to and do not recur so far.

Claims (1)

1. treat a lymphadenomatous Chinese medicine decoction, it is characterized in that it is made up of the material medicine of following weight proportion: Spica Prunellae 20 grams, Concha Ostreae 20 grams, the Radix Astragali 30 grams, Radix Ranunculi Ternati 15 grams, Sargassum 15 grams, Rhizoma Sparganii 12 grams, Rhizoma Curcumae 12 grams, Fructus Forsythiae 10 grams, Radix Scrophulariae 10 grams, 10 grams, Poria, Bombyx Batryticatus 10 grams, Spina Gleditsiae 10 grams, Ramulus Cinnamomi 10 grams.
CN201410537949.5A 2014-09-27 2014-09-27 Traditional Chinese medicine decoction for treating lymphoma Pending CN104258295A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109200248A (en) * 2018-11-20 2019-01-15 温州市中心医院 A kind of Chinese medicine composition for treating lymthoma
CN113797293A (en) * 2021-11-01 2021-12-17 刘世金 Anti-tumor traditional Chinese medicine composition and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102133376A (en) * 2011-03-16 2011-07-27 张新艳 Formula of Chinese medicinal herb for conditioning myoma of uterus
CN103877377A (en) * 2014-04-19 2014-06-25 郑玉霞 Chinese medicament preparation for treating lymphoma and preparation method of Chinese medicament preparation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102133376A (en) * 2011-03-16 2011-07-27 张新艳 Formula of Chinese medicinal herb for conditioning myoma of uterus
CN103877377A (en) * 2014-04-19 2014-06-25 郑玉霞 Chinese medicament preparation for treating lymphoma and preparation method of Chinese medicament preparation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
胡余绍等: "中西医结合治疗颈淋巴结结核临床观察", 《中国中西医结合杂志》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109200248A (en) * 2018-11-20 2019-01-15 温州市中心医院 A kind of Chinese medicine composition for treating lymthoma
CN113797293A (en) * 2021-11-01 2021-12-17 刘世金 Anti-tumor traditional Chinese medicine composition and preparation method thereof

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Application publication date: 20150107