CN104840855A - Traditional Chinese medicine composition for treating pulmonary tuberculosis - Google Patents

Abstract

A traditional Chinese medicine composition for treating pulmonary tuberculosis. The raw material components are as follows in parts by weight: 30-45 parts of Bletilla striata, 9-12 parts of Baibu, 5-20 parts of peach kernel, 5-20 parts of Wulingzhi, 5- 12 parts, 5-12 parts of Ophiopogon japonicus, 10-30 parts of yam, 6-15 parts of Chuanbei, 6-15 parts of Asparagus, 6-20 parts of Yunling, 6-20 parts of oyster, 5-18 parts of turtle shell, 3-10 parts of Magnolia Bark, 10-15 parts of Cordyceps sinensis, 3-15 parts of bellflower, 9-15 parts of Gonggong leaves and 3-9 parts of licorice. The present invention rationally matches the above-mentioned various traditional Chinese medicine raw materials, and the ratio of the given ingredients makes each raw material play a very good synergistic effect, nourishing yin and promoting body fluid, moisturizing the lungs and relieving cough, resolving stagnation and dispelling stagnation, and the combined effect is remarkable in the treatment of tuberculosis .

Description

A kind of traditional Chinese medicine composition for treating pulmonary tuberculosis

Technical field:

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating pulmonary tuberculosis.

Background technique:

Pulmonary tuberculosis (PTB) is a pulmonary infectious disease caused by Mycobacterium tuberculosis, which is a serious threat to human health. The source of infection of Mycobacterium tuberculosis (abbreviated as Mycobacterium tuberculosis, the same below) is mainly pulmonary tuberculosis patients who excrete bacteria and spread through the respiratory tract. Healthy people infected with tuberculosis do not necessarily have the disease, only when the body's immunity is weakened. Statistics from the World Health Organization (WHO) show that 8 to 10 million cases of tuberculosis occur in the world every year, and about 3 million people die from tuberculosis every year. It is the single infectious disease that causes the largest number of deaths.

Invention content:

Aiming at the above existing problems, the present invention provides a traditional Chinese medicine composition for treating pulmonary tuberculosis. The traditional Chinese medicine is developed from pure natural traditional Chinese medicine, has definite curative effect and no toxic or side effects, and has a remarkable effect on treating pulmonary tuberculosis.

In order to achieve the above object, the present invention adopts the following technical solutions:

A traditional Chinese medicine composition for treating pulmonary tuberculosis. The raw material components are as follows in parts by weight: 30-45 parts of Bletilla striata, 9-12 parts of Baibu, 5-20 parts of peach kernel, 5-20 parts of Wulingzhi, 5- 12 parts, 5-12 parts of Ophiopogon japonicus, 10-30 parts of yam, 6-15 parts of Chuanbei, 6-15 parts of Asparagus, 6-20 parts of Yunling, 6-20 parts of oyster, 5-18 parts of turtle shell, 3-10 parts of Magnolia Bark, 10-15 parts of Cordyceps sinensis, 3-15 parts of bellflower, 9-15 parts of Gonggong leaves and 3-9 parts of licorice.

Preferably, in parts by weight, the raw material components are as follows: 40 parts of Bletilla striata, 12 parts of Baibu, 15 parts of walnut kernel, 12 parts of Wulingzhi, 10 parts of Radix Ginseng, 10 parts of Ophiopogon japonicus, 20 parts of Chinese yam, and 12 parts of Chuanbei , 12 parts of asparagus, 10 parts of Yun Ling, 15 parts of oysters, 13 parts of turtle shells, 6 parts of Magnolia officinalis, 12 parts of Cordyceps sinensis, 10 parts of bellflower, 12 parts of Gonggong leaves and 6 parts of licorice.

Among the Chinese medicine composition of the present invention, the pharmacological analysis of each crude drug is as follows:

Bletilla striata: bitter, sweet, astringent, slightly cold in nature. Return lung, liver, stomach warp. It has the effects of astringent and hemostasis, detumescence and granulation promoting.

Libu: Alias: Libucao, angiosperm, is a plant of the family Libaceae. Cure mainly to moisten the lungs, relieve cough, and kill parasites. For chronic cough, tuberculosis cough, pertussis; externally for head lice, body lice, pinworms, genital itching. Moisturizing the lungs and relieving cough. For cough due to yin deficiency.

Peach kernel: sweet in nature, bitter in taste, enters the lung, liver, and large intestine meridian. It has the effects of dispelling blood and promoting blood stasis, moistening dryness and smoothing intestines. For amenorrhea, dysmenorrhea, lump in the abdomen, injury from falling down, dryness of the intestine and constipation.

Wulingzhi: sweet in taste, warm in nature. Go into Liver Channel. Tongli blood vessels, dissipating blood stasis to relieve pain, dispelling blood stasis to stop bleeding.

Radix Ginseng: Nourishing yin and clearing the lungs, resolving phlegm and relieving cough, benefiting the stomach and promoting body fluid. It has the effects of strengthening the heart, significantly and continuously eliminating phlegm, and inhibiting skin fungi.

Ophiopogon japonicus: sweet, slightly bitter, slightly cold. GUIXIN, lung, stomach warp. Nourishing yin and promoting body fluid, nourishing the lungs and clearing the heart. It is used for dry cough due to dryness of the lung, cough due to deficiency, thirsty wound, vexation and insomnia, internal heat and thirst, intestinal dryness and constipation, and pharyngeal diphtheria.

Yam: flat in nature, sweet in taste, non-toxic, has the functions of invigorating the spleen and Qi, nourishing the lungs and stomach, nourishing the kidney and strengthening essence.

Chuanbei: cool in nature, sweet and flat. Go into lung meridian, stomach meridian. It has the effects of moistening the lung and relieving cough, resolving phlegm and relieving asthma, clearing away heat and resolving phlegm.

Asparagus: sweet, bitter, cold in nature. Return lung, kidney channel. Nourishing yin and promoting body fluid, nourishing the lungs and clearing the heart. It is used for dry cough due to dryness of the lung, cough due to consumptive fatigue, thirsty body fluid wound, vexation and insomnia, internal heat quenching one's thirst, intestinal dryness and constipation, and diphtheria.

Yunling: mild in nature, sweet in taste, non-toxic. Functions: Replenish qi and calm the nerves, invigorate the spleen and harmonize the stomach, dispel dampness and heat, flow water to stop leakage, treat qi deficiency and fatigue, fullness of trusted subordinates, edema, diarrhea, forgetfulness, insomnia and other diseases.

Oyster: salty, slightly cold. Return liver, gallbladder, kidney channel. Suppressing liver and subduing yang; calming the nerves; softening hard masses and dispelling stagnation; astringent and astringent. Mainly vertigo and tinnitus; palpitations and insomnia; scrofula gall tumors; lumps in the abdomen; spontaneous sweating, night sweats; nocturnal emission; uterine bleeding; leukorrhea.

Turtle shell: salty in taste, neutral in nature. It has the effects of nourishing yin and suppressing yang, softening and resolving hard masses.

Magnolia officinalis: bitter in the mouth, pungent, warm in nature. It has the effects of dispelling qi and drying dampness, reducing adverse reactions and eliminating ruffian. For dampness stagnation injury, nausea, vomiting and diarrhea, stagnation of Qi due to food accumulation, abdominal distension and constipation, dyspnea and cough due to phlegm retention.

Cordyceps sinensis: It has the effects of regulating immune system function, direct anti-tumor effect, and anti-fatigue.

Platycodon grandiflorum: expectorant, sore throat, pus drainage. Platycodon grandiflorum is bitter in taste, pungent, and flat in nature. Return lung meridian. It can be used for cough with excessive phlegm and chest tightness. This product is pungent, relieves bitterness, releases lung qi, eliminates phlegm, and can be used regardless of cold or heat.

Gonggong leaves: bitter in taste, cool in nature. Return liver, kidney channel. It has the effects of clearing deficiency heat, benefiting liver and kidney, and dispelling rheumatism. Deficiency of yin and labor heat; cough and hemoptysis; dizziness; soreness of the waist and knees; rheumatic arthralgia; vitiligo.

Licorice root: calm in nature, sweet in taste, belongs to the twelve meridians. Raw licorice can clear away heat and detoxify, moisturize the lungs and relieve cough, and reconcile the properties of various medicines; roasted licorice can invigorate the spleen and Qi.

The combination of the above-mentioned medicines makes the efficacy of each medicine produce a synergistic effect, and all the medicines in the prescription are used together to play the effects of nourishing yin and promoting body fluid, moistening the lungs and relieving cough, dispelling stagnation and dispelling stagnation, and jointly achieve the purpose of treating pulmonary tuberculosis.

The beneficial effects of the present invention are:

The present invention rationally matches the above-mentioned various traditional Chinese medicine raw materials, and the ratio of the given ingredients makes each raw material play a very good synergistic effect, nourishing yin and promoting body fluid, moisturizing the lungs and relieving cough, resolving stagnation and dispelling stagnation, and the combined effect is remarkable in the treatment of tuberculosis . Compared with the prior art, the present invention is more optimized, has no adverse reaction, has the advantages of short course of treatment, quick effect and no recurrence after cure.

Detailed ways:

The present invention will be described in detail below in conjunction with the examples, but it is not intended to limit the protection scope of the present invention.

Example 1:

A traditional Chinese medicine composition for treating pulmonary tuberculosis. The raw material components are as follows in parts by weight: 40 grams of Bletilla striata, 12 grams of Baibu, 15 grams of peach kernel, 12 grams of Wulingzhi, 10 grams of Radix Radix, 10 grams of Radix Radix, 20 grams of Chinese yam gram, Chuanbei 12 grams, Asparagus 12 grams, Yunling 10 grams, oyster 15 grams, turtle shell 13 grams, Magnolia officinalis 6 grams, Cordyceps sinensis 12 grams, Campanulaceae 10 grams, Gonggong leaves 12 grams and licorice 6 grams.

Make decoction, concentrated tablet or concentrated capsule according to conventional methods. (1) The preparation method of the decoction is as follows: by weight, take the raw material components and put them in a container, add cold water to cover the medicine surface, soak for 15 to 20 minutes, add water to cover the medicine surface for about 8 cm, and carry out the second step. Cook once. Before boiling, use strong fire to decoct, and after boiling, use slow fire to decoct for 20-30 minutes; for the second decoction, add water to cover about 6 cm of the medicine surface, and decoct for 15-20 minutes after the water boils. Decoct twice to remove the residue and extract the juice, then combine. (2) The preparation method of concentrated tablets or concentrated capsules is as follows: put the above-mentioned Chinese medicine raw materials into a Chinese medicine extraction tank, add 15-20 times the total volume of raw materials for extraction, extract for 8-10 hours, and filter out the medicinal liquid Obtain the extract, concentrate the extract, dry, pulverize, and make tablets or capsules according to the conventional pharmaceutical process, 1g per tablet or capsule.

Usage and dosage: 1 dose of decoction per day, divided into 2 doses, 1 time in the morning and 1 time in the evening, 20 days is a course of treatment, generally 1-4 courses of treatment are required as appropriate; Concentrated tablets or capsules, taken orally, warmed Take with boiling water, 2 times a day, 4-5 capsules each time.

Example 2:

A traditional Chinese medicine composition for treating pulmonary tuberculosis. The raw material components are as follows in parts by weight: 42 grams of Bletilla striata, 12 grams of Baibu, 15 grams of peach kernel, 12 grams of Wulingzhi, 10 grams of Radix Radix Radix, 9 grams of Radix Ophiopogon japonicus, 18 grams of Chinese yam gram, Chuanbei 12 grams, Asparagus 10 grams, Yunling 12 grams, oyster 12 grams, turtle shell 15 grams, Magnolia officinalis 8 grams, Cordyceps sinensis 13 grams, Campanulaceae 12 grams, Gonggong leaves 12 grams and licorice 5 grams.

Its preparation method and usage and consumption are with embodiment 1.

Example 3:

A traditional Chinese medicine composition for treating pulmonary tuberculosis. The raw material components are as follows in parts by weight: 38 grams of Bletilla striata, 10 grams of Baibu, 12 grams of peach kernel, 12 grams of Wulingzhi, 10 grams of Radix Radix, 10 grams of Radix Radix, 15 grams of Chinese yam gram, Chuanbei 9 grams, Asparagus 9 grams, Yunling 10 grams, oyster 12 grams, turtle shell 10 grams, Magnolia officinalis 9 grams, Cordyceps sinensis 11 grams, Campanulaceae 12 grams, Gonggong leaves 12 grams and licorice 8 grams.

Its preparation method and usage and consumption are with embodiment 1.

Example 4:

A traditional Chinese medicine composition for treating pulmonary tuberculosis. The raw material components are as follows in parts by weight: 30 grams of Bletilla striata, 9 grams of Baibu, 5 grams of peach kernels, 5 grams of Wulingzhi, 5 grams of Radix Radix, 5 grams of Ophiopogon japonicus, and 10 grams of Chinese yam. 6 grams, 6 grams of Chuanbei, 6 grams of Asparagus, 6 grams of Yunling, 6 grams of oysters, 5 grams of turtle shells, 3 grams of Magnolia officinalis, 10 grams of Cordyceps sinensis, 3 grams of Campanulaceae, 9 grams of Gonggong leaves and 3 grams of licorice.

Its preparation method and usage and consumption are with embodiment 1.

Example 5:

A traditional Chinese medicine composition for treating pulmonary tuberculosis, the raw material components are as follows in parts by weight: 45 grams of Bletilla striata, 12 grams of Baibu, 20 grams of peach kernel, 20 grams of Wulingzhi, 12 grams of Radix Radix Radix, 12 grams of Radix Ophiopogon japonicus, 30 grams of Chinese yam gram, Chuanbei 15 grams, Asparagus 15 grams, Yunling 20 grams, oyster 20 grams, turtle shell 18 grams, Magnolia officinalis 10 grams, Cordyceps sinensis 15 grams, Campanulaceae 15 grams, Gonggong leaves 15 grams and licorice 9 grams.

Its preparation method and usage and consumption are with embodiment 1.

Embodiment 6:

Efficacy survey

1. Diagnosis basis

According to the "Guidelines for the Implementation of China's Tuberculosis Prevention and Control Program (2002)" standards. The selected patients with pulmonary tuberculosis were all sputum smear positive.

2. General situation

For testing the therapeutic effect of the present invention, choose 75 routine pulmonary tuberculosis patients to give the Chinese medicine composition treatment that above-mentioned embodiment makes. Among them, there were 45 males and 30 females, aged 16-58 years, with an average age of 38 years.

3. Efficacy Judgment Criteria

(1) Clinical cure: symptoms disappear, lung lesions absorb calcification, and sputum examination turns negative;

(2) Effective: Symptoms are improved, and lung lesions are partially absorbed;

(3) Ineffective: no change in symptoms and lesions.

4. Results

After 75 cases of pulmonary tuberculosis took 1-4 courses of treatment of the traditional Chinese medicine composition of the present invention, 60 cases were clinically cured, with a cure rate of 80%; 12 cases were effective, with an effective rate of 16%; 3 cases were ineffective, with an ineffective rate of 4%. The total effective rate is 96%.

5. Side effects

No toxic side effects were found.

Typical cases:

Zhang, man, 22 years old, people from Nanning City, Guangxi, suffering from pulmonary tuberculosis, cough, bloody sputum, night sweats, weak pulse, white tongue coating, diagnosed as pulmonary tuberculosis through bacteriological examination and X-ray examination; take the medicine of the present invention After 10 days of the Chinese medicine composition, there was no blood in the sputum, and after taking the Chinese medicine composition of the present invention for 1 course of treatment, all symptoms disappeared, and the reexamination of sputum bacteria turned negative, and X-ray examination showed that the tuberculosis focus absorbed calcification and was cured. Follow up a case by regular visits to half a year without recurrence.

Tang, female, 31 years old, is from Beihai City, Guangxi. Intermittent fever and dry cough for 1 year, aggravated recently with hemoptysis, fever in the afternoon and at night, cough, night sweats, red tongue with less fluid, weak pulse, and diagnosed as pulmonary tuberculosis by laboratory tests and X-ray examinations; taking the traditional Chinese medicine composition of the present invention After 1 course of treatment, the symptoms improved, and the X-ray examination showed that the lung lesions were partially absorbed, and continued to take 1 course of treatment, and he was cured, and no recurrence has been followed up so far.

Chen, male, 50 years old, from Liuzhou City, Guangxi. Intermittent cough and expectoration for 1 month, aggravated recently with chest tightness and shortness of breath, cough, expectoration, night sweats, chest tightness, shortness of breath, red tongue with less fluid, weak pulse, and was diagnosed as pulmonary tuberculosis by laboratory examination; taking the traditional Chinese medicine combination of the present invention 3 courses of treatment were cured, followed up for 2 years without recurrence.

Claims (2)

1. the phthisical Chinese medicine composition for the treatment of, it is characterized in that, by weight, raw material components is as follows: Pseudobulbus Bletillae (Rhizoma Bletillae) 30-45 part, Radix Stemonae 9-12 part, Semen Persicae 5-20 part, Oletum Trogopterori 5-20 part, Radix Adenophorae (Radix Glehniae) 5-12 part, Radix Ophiopogonis 5-12 part, Rhizoma Dioscoreae 10-30 part, Bulbus Fritillariae Cirrhosae 6-15 part, Radix Asparagi 6-15 part, Poria 6-20 part, Concha Ostreae 6-20 part, Carapax Trionycis 5-18 part, Cortex Magnoliae Officinalis 3-10 part, Cordyceps 10-15 part, Radix Platycodonis 3-15 part, Folium Mahoniae 9-15 part and Radix Glycyrrhizae 3-9 part.

2. the phthisical Chinese medicine composition for the treatment of as claimed in claim 1, it is characterized in that, by weight, raw material components is as follows: the Pseudobulbus Bletillae (Rhizoma Bletillae) 40 parts, the Radix Stemonae 12 parts, 15 parts, Semen Persicae, Oletum Trogopterori 12 parts, Radix Adenophorae (Radix Glehniae) 10 parts, Radix Ophiopogonis 10 parts, Rhizoma Dioscoreae 20 parts, Bulbus Fritillariae Cirrhosae 12 parts, Radix Asparagi 12 parts, Poria 10 parts, Concha Ostreae 15 parts, Carapax Trionycis 13 parts, Cortex Magnoliae Officinalis 6 parts, Cordyceps 12 parts, Radix Platycodonis 10 parts, Folium Mahoniae 12 parts and 6 parts, Radix Glycyrrhizae.