CN104027651A

CN104027651A - Eye drops for treating eye diseases

Info

Publication number: CN104027651A
Application number: CN201410294781.XA
Authority: CN
Inventors: 郑增友
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-06-27
Filing date: 2014-06-27
Publication date: 2014-09-10

Abstract

The invention provides eye drops for treating eye diseases. Active ingredients of the eye drops are calamine, herba equiseti hiemalis, butterflybush flower, semen cassia, tabasheer, bat dung, wild chrysanthemum flower, caulis akebiae, radix scrophulariae, bluestone, pipewort, mirabilite, vatica astrotricha and coptidis rhizome. The product is an external-application liquid water product, and does not contain any unnatural chemical component. The eye drops disclosed by the invention have curative effect for eye diseases such as cataract, glaucoma, presbyopia, juvenile myopia, trachoma, acute ophthalmia, dark eye circles, diabetic eye diseases, fundus hemorrhage, and the like.

Description

A kind of collyrium for the treatment of ophthalmic

Technical field

The invention belongs to tcm field, relate to a kind of collyrium that can treat ophthalmic.

Background technology

Along with the raising of people's living standard and the quickening of rhythm of life, each electronic product has become the necessary of life, but to allow eyes obtain time of having a rest fewer and feweri simultaneously.The sickness rate of all kinds of oculopathy also rises year by year, is tending towards becoming younger, variation.Cataract and keratopathy are the large main blinding oculopathy of China three, therefore very urgent to the love of eyes health.I talks about in < < Classic of the Virtue of the Tao > >: " five colors make us blindness; It is deaf that the five notes of traditional Chinese music make us; It is refreshing that the five tastes make us mouth; Galloping goes hunting hunts, and makes us the heart and goes mad; Rare goods, makes us capable harm ... ".The five colors make us blindness except disclosing abstruse Philosophical Significance, for treatment oculopathy, also have positive directive significance, and eyes are limited for various visual stimulus, and blindness is exactly inevitable outcome excessively afterwards.

For the patient who has suffered from oculopathy, need to correct on the one hand it and be accustomed to eye, also need on the other hand the auxiliary treatment of certain medicine.Collyrium is the conventional medicine for the treatment of disease of eye, and its composition has numerous species, such as steroid, antibiotic, antihistaminic, beta-blocker, on-steroidal anti-inflammation analgesic etc. according to the difference of effect.General collyrium has added micro-antiseptic for long-term preservation, under normal use, can not impact human body.But if the collyrium that life-time service contains antiseptic is easier to cause cornea injured, there is the symptoms such as one's eyes became bloodshot, photophobia.

Chinese medicine is of long standing and well established, and in treatment during ophthalmic, most important viewpoint is exactly to pay attention to especially the relation of eye and internal organs meridians, qi-blood-body fluid.The large puzzled opinion > of < < Ling Shu Miraculous Pivot or Divine Axis >: " the essence of five ZANG-organs and six FU-organs gas is noted in order on all and essence for it.The eye being the nest of essence, the essence of the kidney manifesting in pupil, the essence of the liver manifesting in the black part of eye, the essence of the heart replenishing in the venules of eye, its nest the essence of the lung manifesting in the white part of eye, the essence of the spleen manifesting in the eyelids, wraps up in the essence of picking muscles and bones vim and vigour, and with arteries and veins for being, above belong to brain, after in item." and meridians are operation whole body QI and blood, play communication the exterior and the interior upper and lower at human body, the effect of contact internal organs organ.< < Ling Shu Miraculous Pivot or Divine Axis pathogen cacosplanchnia shape piece of writing > >: " its vim and vigour all go up in face and walk sky key for the twelve regular channels, 365 networks, on its vivid YANG QI, walk order and for it essence." this all illustrates between eye and internal organs, is to connect by the connection of meridians, is keeping organically contact.Be that meridians are constantly carried QI and blood, just maintained the visual performance of eye.

The present invention, according to moral spring hall medicine spectrum secret recipe, is improved, and is incorporated tcm health preserving theory on basis handed down from one's ancestors, successfully develops a kind of collyrium for the treatment of ophthalmic.

Chinese herb medicine eye liquid medicine of the present invention, its raw material is green plants, is rare Chinese medicine formula; This product is external application liquid water dress product, containing any denaturalization, does not study minute.All 72 ophthalmic diseasess such as cataract, presbyopia, adolescent myopia, trachoma, outburst acute catarrhal conjunctivitis, black eye, diabetes salt, retinal hemorrhage are had to curative effect.Without any side effects through long-term practice proof.

Technology contents

The object of this invention is to provide a kind of collyrium for the treatment of multiple ophthalmic, this collyrium can be used for treating the multiple ophthalmic diseasess such as cataract, presbyopia.

The collyrium that the present invention treats multiple ophthalmic is formed by following preparation of raw material: Calamina, Herba Equiseti Hiemalis, Flos Buddlejae, Semen Cassiae, Concretio Silicea Bambusae, Faeces Vespertilionis, Flos Chrysanthemi Indici, Caulis Akebiae, Radix Scrophulariae, Chalcanthitum, Flos Eriocauli, Mirabilitum < Natrii Sulfas >, Pericarpium Citri Reticulatae Viride, Rhizoma Coptidis.

The present invention treats the collyrium medicinal liquid of multiple ophthalmic, and the weight portion proportioning of the various Chinese crude drugs of selecting is:

30 parts of Calaminas, 30 parts of Herba Equiseti Hiemalis, 20 parts of Flos Buddlejaes, 30 parts of Semen Cassiaes, 30 parts of Concretio Silicea Bambusaes, 30 parts of Faeces Vespertilioniss, 20 parts of Flos Chrysanthemi Indicis, 10 parts of Caulis Akebiaes, 20 parts of Radix Scrophulariaes, 10 parts, Chalcanthitum, 30 parts of Flos Eriocaulis, 10 parts of Mirabilitum < Natrii Sulfas >, 10 parts, Pericarpium Citri Reticulatae Viride, 30 parts of Rhizoma Coptidis.

The present invention treats the collyrium of multiple ophthalmic with reference to plurality of medical pharmacopeia, is aided with the optimization of clinical application for many years simultaneously, has overcome the problem of taboo combination, specifically selects the pharmacological basis of Chinese medicine to be:

Calamina: removing toxic substances improving acuity of vision and removing nebula, the antipruritic sore of removing dampness., eczema dripping for conjunctival congestion and swelling pain, marginal blepharitis, nebula film bulbar conjunctiva polyp, ulcer being unable to heal, pus and skin pruritus.

Herba Equiseti Hiemalis: treatment conjunctival congestion and swelling pain, Chinese medicine Herba Equiseti Hiemalis has effect and the effect of clearing away heat to improve acuity of vision, as well-known doctor Zhang Shanlei, says: " Chinese medicine Herba Equiseti Hiemalis, all diseases of the wooden evil perverse and unreasonable manner for the treatment of liver and gall, the corneal nebula that can disappear, removing mass is stagnant, all wears down the use of having a surplus also.Then the key medicine person of Wei Mu section, Gu not only get its gram of wood, can rub and hide from view, also contain dispelling wind, let out removing dampness heat, rise the loose all justice of stagnated fire.”

Flos Buddlejae: there is heat clearing away nourishing the liver, the effect of improving acuity of vision and removing nebula.Be used for the treatment of conjunctival congestion and swelling pain, many tear photophobia, the nebula of looking unfamiliar film, hepatasthenia dim eyesight, blurring of vision.In < < Bencao Haili > >, record " profit liver is dry, controls blood vessel in order for Flos Buddlejae, sweet being slightly cold, optic atrohic blindness nebula, and red swollen gum eye, children's's infantile malnutrition gas is attacked eye.”

Semen Cassiae: sweet in the mouth, salty, bitter, cold nature.Return liver, large intestine channel.The function of tool clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.Raw Semen Cassiae is longer than removing heat from the liver, and intestine moistening is dry.For conjunctival congestion and swelling pain, constipation.

Concretio Silicea Bambusae: clear heat and eliminate phlegm, cool heart arresting convulsion.Cure mainly calentura coma delirium, middle wind-phlegm fan in silence, twitch, epilepsy by infantile convulsion.Phlegm-heat cough.

Faeces Vespertilionis: original name sky Mus dung, crude drug is the dry feces of Vespertilio class animal.< < Bencao Jingshu > >: Faeces Vespertilionis, the main improving eyesight of moderns, controls blindness and hide from view.Its acrid in the mouth is cold, is into meridian of Foot-JUE YIN medicine, and < < herbal classic > > leads all cards, total belong to be through send out, get the loose inside and outside knot of its pungent energy stagnant, therefore the heap soil or fertilizer over and around the roots of cold energy dehematize steam is also.Though right main treatment is many, property has exclusive, and outside improving eyesight, Yu Jieke slightly.

Flos Chrysanthemi Indici: heat, the improving eyesight that clears away heart-fire, wind and heat dispersing, clear swollen the alleviating pain of disappearing avoids heat.< < Shanxi Chinese medicinal herbal > >: dispelling wind heat, refresh oneself, pathogenic fire reducing removing toxic substances.Control all dizziness due to wind pathogen dizzy, headache, conjunctival congestion, toxic swelling.

Caulis Akebiae: clearing away heart-fire, diuresis, the stimulating milk secretion of stimulating the menstrual flow.

Radix Scrophulariae: cure mainly epidemic febrile disease and nutrient blood, fever of the body, excessive thirst, crimson tongue, send out speckle, hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency not awake, Tianjin hinder constipation, order puckery dim-sighted, throat larynx swells and ache, scrofula sucutaneous nodule, skin sore.

Chalcanthitum: have emetic, putrefaction removing, the effect of removing toxic substances; Control wind-phlegm and be jammed, sore throat, epilepsy, ulcerative gingivitis, aphtha, marginal blepharitis eye, hemorrhoid, the effect of toxic swelling and have certain side effect.

Flos Eriocauli: wind and heat eliminating, improving acuity of vision and removing nebula.Control corneal nebula, night blindness, headache, toothache, time numbness, epistaxis.< < Compendium of Materia Medica > >: " the light property of Flos Eriocauli body is floating, can the bright dividing line of up sun.Allly control all diseases in order, add and with it, very good.The merit of improving acuity of vision and removing nebula, like on Flos Chrysanthemi also.”

Mirabilitum: there is purging heat to relax the bowels, moistening for dryness and softening hard mass, the effect of the detumescence of relieving inflammation or internal heat.

Pericarpium Citri Reticulatae Viride: there is soothing the liver dispelling the stagnated QI, the stagnant effect of removing food stagnancyization.Be used for the treatment of distending pain in the chest and hypochondrium, hernia, nodule in the breast, acute mastitis, abdominal pain due to retention of food.

Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.The kind clear part of the body cavity above the diaphragm housing the heart and lungs of Rhizoma Coptidis (processed with wine) is burning hot.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.For cold and heat, tie mutually damp and hot middle resistance, feeling of fullness vomiting.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.

Concrete embodiment

(1) take and concoct 30 grams of rear Herba Equiseti Hiemalis, 20 grams of Flos Buddlejaes, 30 grams of Semen Cassiaes, 30 grams of Concretio Silicea Bambusaes, 30 grams of Faeces Vespertilioniss, 20 grams of Flos Chrysanthemi Indicis, 10 grams of Caulis Akebiaes, 20 grams of Radix Scrophulariaes, 30 grams of Flos Eriocaulis, 10 grams, Pericarpium Citri Reticulatae Viride, 30 grams of Rhizoma Coptidis, add 2.5kg clear water to decoct 1 hour.

(2) cooling, filter, filtering residue adds 1.3kg clear water to decoct 0.5 hour, filters.Merging filtrate, standing 5 hours, filter, it was 1.1 (being about 1.2kg) that filtrate is concentrated into relative density.

(3) add 95% ethanol 1000mL, stir 30 minutes, refining 5 hours, filter, filtrate concentration and recovery ethanol is extremely without alcohol taste.Add 30 grams of Calaminas, 10 grams, Chalcanthitum, 10 grams of Mirabilitum < Natrii Sulfas >, with water for injection, be diluted to every 1mL containing crude drug 1g, standing 8 hours, standby.

(4) filter, filtrate checks that pH value is 4.5-5.0, fine straining, the ultrafiltration of 10kg pressure, inflated with nitrogen embedding, 110-120 degree sterilizing 30 minutes, lamp inspection, packing, warehouse-in.

Claims

1. treat a liquid medicine for ophthalmic, its technical characterictic is comprised of following active Chinese medicine ingredients for this liquid medicine: Calamina, Herba Equiseti Hiemalis, Flos Buddlejae, Semen Cassiae, Concretio Silicea Bambusae, Faeces Vespertilionis, Flos Chrysanthemi Indici, Caulis Akebiae, Radix Scrophulariae, Chalcanthitum, Flos Eriocauli, Mirabilitum < Natrii Sulfas >, Pericarpium Citri Reticulatae Viride, Rhizoma Coptidis.

2. treat as claimed in claim 1 the liquid medicine of ophthalmic, the weight portion proportioning of contained effective ingredient is: 30 parts of Calaminas, 30 parts of Herba Equiseti Hiemalis, 20 parts of Flos Buddlejaes, 30 parts of Semen Cassiaes, 30 parts of Concretio Silicea Bambusaes, 30 parts of Faeces Vespertilioniss, 20 parts of Flos Chrysanthemi Indicis, 10 parts of Caulis Akebiaes, 20 parts of Radix Scrophulariaes, 10 parts, Chalcanthitum, 30 parts of Flos Eriocaulis, 10 parts of Mirabilitum < Natrii Sulfas >, 10 parts, Pericarpium Citri Reticulatae Viride, 30 parts of Rhizoma Coptidis.