CN104689107B - It is a kind of to be used to treat Chinese medicine composition of myopia and preparation method thereof - Google Patents
It is a kind of to be used to treat Chinese medicine composition of myopia and preparation method thereof Download PDFInfo
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Abstract
It is a kind of to be used to treat Chinese medicine composition of myopia and preparation method thereof, it is related to the field of Chinese medicines, is made up of the raw material of following parts by weight：10 15 parts of cassia seed, 10 15 parts of the fruit of glossy privet, 79 parts of chrysanthemum, 57 parts of the fruit of Chinese wolfberry, 57 parts of plantain seed, 57 parts of the tuber of dwarf lilyturf, 35 parts of mother-of-pearl, 10 15 parts of the membrane of a chicken's gizzard, 10 15 parts of mulberry fruit, 35 parts of the root of Dahurain angelica, 35 parts of asarum, 13 parts of cultivated land, 13 parts of Radix Codonopsis, 57 parts of lophatherum gracile；The popularization of the present invention can provide a kind of Chinese medicine composition that can treat myopia, the effect of with clearing heat and detoxicating, dispersing stagnated hepatoqi, blood circulation-activating eyesight-improving, for treating myopia caused by a variety of causes, patient is set to be improved in a short time eyesight, have no toxic side effect, therapeutic effect is notable.
Description
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of Chinese medicine composition and its preparation side for being used to treat myopia
Method.
Background technology
Myopia, names of disease of tcm.Be eye in the case where adjusting relaxed state, parallel rays focus after the refraction of the dioptric system of eye
Fall before retina.Ancient medical book is early recognized to this disease, and referred to as mesh is unable to long sight, also known as the nearly timid remote disease of energy, extremely《Mesh is through big
Into》Begin to claim myopia.By congenital generation, myopic degree the higher person is also known as closely looked.The generation and heredity, development, environment etc. of myopia are all
Multifactor relevant but definite pathogenesis is still under study for action.Myopia has a variety of origin causes of formation, such as due to being drawn with eye mode is bad
The myopia risen, it is near-sighted caused by heredity, due to drug-induced myopia etc..Its incidence of disease has what is risen year by year in recent years
Trend, especially juvenile onset rate become apparent, and there is no preferable medicine at present, majority using wear glasses,
Health-care appliance is treated, in severe case using the health care such as operative treatment, current market sales of eye-protection instrument, physiotherapeutic glasses for myopia
It instrument, although some effects, can not cure, and easily recur and aggravate the state of an illness；Also there are some medicines, effect is bad, treatment
Time is grown；There is great risk in operative treatment, and sequelae is more.Why related drugs on the market and therapeutic equipments be not up to
To the purpose effected a permanent cure, it is because treatment myopia is Huoxue Shugan at all, have left this and go blindly searching treatment near at all
Depending on the medicine or method of eye illness presentation, can all there are bad effect, high recurrence rate or even aggravate the adverse consequences such as the state of an illness.
The content of the invention
The purpose of the present invention has the trend risen year by year, especially juvenile onset rate aiming at its incidence of disease in recent years
Become apparent, and there is no preferable medicine at present, it is most using wear glasses, health-care appliance is treated, in serious conditions
It is lower to use the health care instrument such as operative treatment, current market sales of eye-protection instrument, physiotherapeutic glasses for myopia, although some effects, not
It can cure, and easily recur and aggravate the state of an illness；Also there are some medicines, effect is bad, treatment time length；Operative treatment presence is very big
Risk, and the deficiency that sequelae is more, and a kind of Chinese medicine composition for being used to treat myopia is provided, treatment of the present invention
The Chinese medicine composition of myopia has the effect of dispersing stagnated hepatoqi, blood circulation-activating eyesight-improving, is fundamentally treated by dispersing liver and promoting blood circulation to reach
The purpose of myopia.
The present invention is made up of the raw material of following parts by weight：Cassia seed 10-15 parts, fruit of glossy privet 10-15 parts, chrysanthemum 7-9 parts, Chinese holly
Matrimony vine 5-7 parts, plantain seed 5-7 parts, tuber of dwarf lilyturf 5-7 parts, mother-of-pearl 3-5 parts, the membrane of a chicken's gizzard 10-15 parts, mulberry fruit 10-15 parts, the root of Dahurain angelica
3-5 parts, asarum 3-5 parts, cultivated land 1-3 parts, Radix Codonopsis 1-3 parts, lophatherum gracile 5-7 parts.
Preferably, it is made up of the raw material of following parts by weight：13 parts of cassia seed, 13 parts of the fruit of glossy privet, 8 parts of chrysanthemum, the fruit of Chinese wolfberry 6
Part, 6 parts of plantain seed, 6 parts of the tuber of dwarf lilyturf, 4 parts of mother-of-pearl, 13 parts of the membrane of a chicken's gizzard, 13 parts of mulberry fruit, 4 parts of the root of Dahurain angelica, 4 parts of asarum, 2 parts of cultivated land,
2 parts of Radix Codonopsis, 6 parts of lophatherum gracile.
The preparation method of above-mentioned Chinese medicine preparation includes below step：
(1) by cassia seed, the fruit of glossy privet, chrysanthemum, the fruit of Chinese wolfberry, plantain seed, the tuber of dwarf lilyturf, mother-of-pearl, the membrane of a chicken's gizzard, mulberry fruit, the root of Dahurain angelica,
Asarum, cultivated land, Radix Codonopsis, lophatherum gracile first with 2 ° of -5 ° of cold water soaks 5 hours, are put into drying box and are dried, dry box temperature after immersion
At 46 ° -50 °, drying time is 20 minutes for degree control, standby after placement room temperature；
(2) dried cassia seed is taken, the fruit of glossy privet, chrysanthemum, the fruit of Chinese wolfberry, plantain seed grinds, and is ground into 300-400 mesh
Micro mist, micro mist is put into fill 75% ethanol water, refluxing extraction 5 times, it is standby that extract solution is then concentrated into medicinal extract；
(3) the dried tuber of dwarf lilyturf is taken, mother-of-pearl, the membrane of a chicken's gizzard, mulberry fruit, the root of Dahurain angelica, asarum, cultivated land, Radix Codonopsis, lophatherum gracile is put into
Pounded in container, holding container temperature is pounded into graininess, is then placed in decoction container, decoction 3 times, often under 30 DEG C of environment
It is secondary to decoct 0.5 hour, then obtained decoction liquor is filtered, the filtrate after filtering is taken, medicinal extract is made in filtrate boiling concentration
It is standby；
(4) medicinal extract that the 2nd step and the 3rd step obtain is well mixed, be then dried, it is 300- to be crushed again after drying
The micro mist of 400 mesh, obtained micro mist is added after filler, adhesive tablet, pill, paste is made or loads gelatin hard
Capsule.In above-mentioned each traditional Chinese medicine ingredients：
Cassia seed, cassia seed, bitter but sweet flavor is cool in nature, there is clearing liver, improving eyesight, can control wind-heat cute conjunctivitis, glaucoma, night blindness etc.
Take a disease, be monarch drug in a prescription.
The fruit of glossy privet, liver and kidney benefiting, clearind deficient heat, improving eyesight.Cure mainly：Light-headedness, soreness and weakness of waist and knees, seminal emission, poliosis, hectic fever due to yin tide
Heat, mesh are secretly failed to understand, the deficiency of liver-yin and kidney-yin, are monarch drug in a prescription.
Chrysanthemum, mildly bitter flavor, property gas peace, there is the effect of scattered wind heat-clearing, flat liver improving eyesight, be ministerial drug.
The fruit of Chinese wolfberry, it is sweet, property gas peace, there is nourshing kidney, moistening lung, tonifying liver, be ministerial drug the effect of improving eyesight.
Plantain seed, sweet, cold nature, there is reducing fever and causing diuresis, excreting dampness is treating stranguria, improving eyesight, is ministerial drug the effect of eliminating the phlegm.
The tuber of dwarf lilyturf, sweet, slight bitter, cold nature, there is the effect of nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire, be ministerial drug.
Mother-of-pearl, taste is micro- salty, cold nature, has the effect of calming the liver, improving eyesight of calming the frightened, is adjutant.
The membrane of a chicken's gizzard, it is sweet, property gas peace, there is the effect of stomach strengthening and digestion promoting, arresting seminal emission, be adjutant.
Mulberry fruit, sweet, sour, cold nature, there is the effect of enriching yin of enriching blood, fluid dryness, be adjutant.
The root of Dahurain angelica, acrid flavour, it is warm-natured and, have and dissipate wind and dehumidify, sensible analgesic, be adjutant the effect of detumescence and apocenosis.
Asarum, acrid flavour, it is warm-natured and, there is expelling wind and clearing away cold, sensible analgesic, be adjutant the effect of Wenfei of drink.
Cultivated land, it is sweet, it is warm-natured and, have enrich blood enriching yin the effect of, to make medicine.
Radix Codonopsis, it is sweet, property gas peace, there is the effect of tonifying middle-Jiao and Qi, strengthening spleen and tonifying lung, to make medicine.
Lophatherum gracile, sweet, cold nature, there is the effect of clearing heat and relieving fidgetness, diuresis, to make medicine.
The method have the advantages that：
The present invention can provide a kind of Chinese medicine composition for treating myopia, have clearing heat and detoxicating, dispersing stagnated hepatoqi, promoting blood circulation bright
Purpose effect, for treating myopia caused by a variety of causes, patient is set to be improved in a short time eyesight, nontoxic pair
Effect, therapeutic effect are notable.
Embodiment
The present invention is made up of the raw material of following parts by weight：Cassia seed 10-15 parts, fruit of glossy privet 10-15 parts, chrysanthemum 7-9 parts, Chinese holly
Matrimony vine 5-7 parts, plantain seed 5-7 parts, tuber of dwarf lilyturf 5-7 parts, mother-of-pearl 3-5 parts, the membrane of a chicken's gizzard 10-15 parts, mulberry fruit 10-15 parts, the root of Dahurain angelica
3-5 parts, asarum 3-5 parts, cultivated land 1-3 parts, Radix Codonopsis 1-3 parts, lophatherum gracile 5-7 parts.
Embodiment 1：
Preferably, it is made up of the raw material of following parts by weight：13 parts of cassia seed, 13 parts of the fruit of glossy privet, 8 parts of chrysanthemum, the fruit of Chinese wolfberry 6
Part, 6 parts of plantain seed, 6 parts of the tuber of dwarf lilyturf, 4 parts of mother-of-pearl, 13 parts of the membrane of a chicken's gizzard, 13 parts of mulberry fruit, 4 parts of the root of Dahurain angelica, 4 parts of asarum, 2 parts of cultivated land,
2 parts of Radix Codonopsis, 6 parts of lophatherum gracile.
Specific preparation method following steps：
(1) by cassia seed, the fruit of glossy privet, chrysanthemum, the fruit of Chinese wolfberry, plantain seed, the tuber of dwarf lilyturf, mother-of-pearl, the membrane of a chicken's gizzard, mulberry fruit, the root of Dahurain angelica,
Asarum, cultivated land, Radix Codonopsis, lophatherum gracile first with 2 ° of -5 ° of cold water soaks 5 hours, are put into drying box and are dried, dry box temperature after immersion
At 46 ° -50 °, drying time is 20 minutes for degree control, standby after placement room temperature；
(2) dried cassia seed is taken, the fruit of glossy privet, chrysanthemum, the fruit of Chinese wolfberry, plantain seed grinds, and is ground into 300-400 mesh
Micro mist, micro mist is put into fill 75% ethanol water, refluxing extraction 5 times, it is standby that extract solution is then concentrated into medicinal extract；
(3) the dried tuber of dwarf lilyturf is taken, mother-of-pearl, the membrane of a chicken's gizzard, mulberry fruit, the root of Dahurain angelica, asarum, cultivated land, Radix Codonopsis, lophatherum gracile is put into
Pounded in container, holding container temperature is pounded into graininess, is then placed in decoction container, decoction 3 times, often under 30 DEG C of environment
It is secondary to decoct 0.5 hour, then obtained decoction liquor is filtered, the filtrate after filtering is taken, medicinal extract is made in filtrate boiling concentration
It is standby；
(4) medicinal extract that the 2nd step and the 3rd step obtain is well mixed, be then dried, it is 300- to be crushed again after drying
The micro mist of 400 mesh, obtained micro mist is added after filler, adhesive tablet, pill, paste is made or loads gelatin hard
Capsule.Clinical observation on the therapeutic effect
1st, general information
Selection of clinical Patients with 300 Cases, wherein man 150, female 150, wherein 10-15 year 75,15-25 year 75,25-
35 years old 75,35-45 year 75.
2nd, diagnostic criteria
It is effective：Eyesight quickly improves, and observes 3 months without bounce-back person.
Take a turn for the better：Eyesight slightly improves, and can maintain and not deteriorate in existing eyesight level.
It is invalid：It is invalid after medication.
3rd, treatment method
Using embodiment 1, manufactured capsule, every 1g containing crude drug are early, middle and late daily respectively to take one to patient
Grain, 15 days as one therapeutic course, at least takes 3 courses for the treatment of.
4th, treatment results
Treated for medicine made of 300 clinical samples progress Chinese medicine preparations of the present invention, therapeutic effect is such as
Under：
Clinical samples total number of persons：300 people
| Treatment time | Effective number | Improvement number | Invalid number | Inefficiency |
| 3 courses for the treatment of | 280 | 150 | 5 | 1.7% |
| 6 courses for the treatment of | 290 | 250 | 3 | 1% |
The clinical samples to be taken a turn for the better to 200 therapeutic effects be discontinued 2 years and observed, and recurrence is as follows：
Model case is as follows：
Case 1, Liu, man 15 years old, suffer from high myopia, object at the moment can not be seen, use the product 3 of embodiment 1
It after the individual course for the treatment of, can substantially feel that eyesight improves, after being continuing with 6 courses for the treatment of, vision restoration to 1.0, be discontinued 2 years, ignored
Power bounce-back sign, has no adverse reaction.
Case 2, it is neat certain, female 24 years old, two eye visions are 0.5, before once with laser surgery treatment mistake, but eyesight after 1 year
Bounce-back, eyesight are returned to 0.5, after 3 courses for the treatment of of product of embodiment 1, vision restoration to 0.8, are continuing with 6 courses for the treatment of
Afterwards, vision restoration has been discontinued 2 years, do not rebound sign to 1.2.
Case 3, into certain, female 35 years old, binocular vision 0.4, continue myopia nearly 25 years, tried it is various treatment myopia medicines
Thing, without positive effect, after 10 courses for the treatment of of product of embodiment 1, binocular vision all reaches 0.8, at present still in the treatment.
Certainly, the present invention can also have other various embodiments, in the case of without departing substantially from spirit of the invention and its essence,
Those skilled in the art when can be made according to the present invention it is various it is corresponding change and deformation, but these it is corresponding change and
Deformation should all belong to protection scope of the present invention.
Claims (3)
1. a kind of Chinese medicine composition for being used to treat myopia, is made from the following raw materials in parts by weight：Cassia seed 10-15 parts, female
Loyal sub- 10-15 parts, chrysanthemum 7-9 parts, fruit of Chinese wolfberry 5-7 parts, plantain seed 5-7 parts, tuber of dwarf lilyturf 5-7 parts, mother-of-pearl 3-5 parts, the membrane of a chicken's gizzard
10-15 parts, mulberry fruit 10-15 parts, root of Dahurain angelica 3-5 parts, asarum 3-5 parts, cultivated land 1-3 parts, Radix Codonopsis 1-3 parts, lophatherum gracile 5-7 parts.
A kind of 2. Chinese medicine composition for being used to treat myopia according to claim 1, by the raw material system of following parts by weight
Into：13 parts of cassia seed, 13 parts of the fruit of glossy privet, 8 parts of chrysanthemum, 6 parts of the fruit of Chinese wolfberry, 6 parts of plantain seed, 6 parts of the tuber of dwarf lilyturf, 4 parts of mother-of-pearl, in chicken
13 parts of gold, 13 parts of mulberry fruit, 4 parts of the root of Dahurain angelica, 4 parts of asarum, 2 parts of cultivated land, 2 parts of Radix Codonopsis, 6 parts of lophatherum gracile.
A kind of 3. preparation method as claimed in claim 1 or 2 for being used to treat the Chinese medicine composition of myopia, it is characterised in that
Including below step：
(1) by cassia seed, the fruit of glossy privet, chrysanthemum, the fruit of Chinese wolfberry, plantain seed, the tuber of dwarf lilyturf, mother-of-pearl, the membrane of a chicken's gizzard, mulberry fruit, the root of Dahurain angelica, carefully
Pungent, cultivated land, Radix Codonopsis, lophatherum gracile first with 2 ° of -5 ° of cold water soaks 5 hours, is put into drying box and is dried after immersion, drying box temperature
At 46 ° -50 °, drying time is 20 minutes for control, standby after placement room temperature；
(2) dried cassia seed is taken, the fruit of glossy privet, chrysanthemum, the fruit of Chinese wolfberry, plantain seed grinds, and it is micro- to be ground into 300-400 purposes
Powder, micro mist is put into fill 75% ethanol water, refluxing extraction 5 times, it is standby that extract solution is then concentrated into medicinal extract；
(3) the dried tuber of dwarf lilyturf is taken, mother-of-pearl, the membrane of a chicken's gizzard, mulberry fruit, the root of Dahurain angelica, asarum, cultivated land, Radix Codonopsis, lophatherum gracile is put into container
Inside pound, holding container temperature is pounded into graininess under 30 DEG C of environment, is then placed in and decocts in container, decoct 3 times, decoct every time
Boil 0.5 hour, then obtained decoction liquor is filtered, take the filtrate after filtering, it is standby that filtrate boiling concentration is made into medicinal extract；
(4) medicinal extract that the 2nd step and the 3rd step obtain is well mixed, be then dried, it is 300-400 to be crushed again after drying
Purpose micro mist, obtained micro mist is added after filler, adhesive tablet, pill, paste is made or loads snap fit capsule.
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| CN105031227A (en) * | 2015-09-11 | 2015-11-11 | 上海婉静纺织科技有限公司 | Traditional Chinese medicine for treating myopia |
| CN110179890A (en) * | 2019-07-05 | 2019-08-30 | 于丽文 | A kind of prevention and treatment myopia and its Chinese medicine composition of complication and preparation method thereof |
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| CN102861173A (en) * | 2011-07-04 | 2013-01-09 | 欧亮 | Traditional Chinese medicine preparation method for treating myopia |
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| CN1895552A (en) * | 2006-06-12 | 2007-01-17 | 大理白族自治州中药制药有限责任公司 | Preparation of compound mixture and its inspection |
| CN102000279A (en) * | 2010-11-22 | 2011-04-06 | 李宗智 | Traditional Chinese medicine for treating myopia eye diseases |
| CN102861173A (en) * | 2011-07-04 | 2013-01-09 | 欧亮 | Traditional Chinese medicine preparation method for treating myopia |
| CN102441070A (en) * | 2011-12-06 | 2012-05-09 | 北京同御康泰科技有限公司 | Composition for alleviating eye fatigue |
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