CN102000279A - Traditional Chinese medicine for treating myopia eye diseases - Google Patents

Traditional Chinese medicine for treating myopia eye diseases Download PDF

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CN102000279A
CN102000279A CN 201010552778 CN201010552778A CN102000279A CN 102000279 A CN102000279 A CN 102000279A CN 201010552778 CN201010552778 CN 201010552778 CN 201010552778 A CN201010552778 A CN 201010552778A CN 102000279 A CN102000279 A CN 102000279A
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chinese medicine
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fructus
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CN102000279B (en
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李宗智
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Abstract

The invention discloses a traditional Chinese medicine for treating myopia eye diseases and relates to a medicament prepared by taking the traditional Chinese medicine as a raw material. The traditional Chinese medicine is prepared from 16 kinds of medicinal materials comprising cassia seed, salvia miltiorrhiza, glossy privet fruit, common nasturtium herb, yam, adenophora tetraphylla, forsythia core, raspberry, poria, tuber of dwarf lilyturf, tribulus terrestris, lophatherum gracile, semen plantaginis, motherwort fruit, astragalus root and uncaria laevigata. Proved by clinical use result, the traditional Chinese medicine prescription for treating the myopia eye diseases has the efficacies of clearing and nourishing lever, nourishing kidney and improving the acuity of vision, dispelling the wind, relieving spasm and promoting the generation of visual cells, can promote the repair of optic nerve and retina cell, enhance the stability of a vitreous body and prevent the retina from falling off, can be used for treating myopia, visual fatigue and other suffered diseases caused by various reasons, has unique formula and curative effect, has especial efficacies for children and juvenile patients and can ensure that the symptoms of the patients are eliminated and the visions of the patients are recovered.

Description

A kind of Chinese medicine for the treatment of near-sighted ophthalmic
Technical field
The present invention relates to pharmaceutical composition, in particular to the medicine that with the Chinese herbal medicine is the treatment myopia of preparation of raw material.
Background technology
Eyes are one of most important sensory organ of human body, and myopia is that common ophthalmology takes a disease.The myopia disease has the multiple origin cause of formation, for example because with the bad myopia that causes of eye mode, owing to the hereditary myopia that causes, because drug-induced myopia or the like.The myope has the blurring of vision symptom usually; The patient that other ophthalmics are arranged also has that order is dark, blurred vision, conjunctival congestion, many tear, symptom such as hide from view.
China has accumulated rich experience over thousands of year aspect treatment myopia takes a disease.In recent years, had many treatment myopia the Chinese medicine preparation application patent of invention, for example No. 91103283.5, Chinese patent application " preparation of amblyopia ball and take method ", No. 93121249.9 " a kind of near-sighted treatment by Chinese herbs type health care medicine ", 98121617.x number " Chinese medicine pill that treating catarct is used and production method thereof ", No. 01120241.6 " a kind of Chinese medicine preparation and manufacture method for the treatment of disease of eye " application part etc.; Also have some patent applications that vision is kept healthy, as No. 96120157.6 " a kind of health beverage " and No. 96120158.4 " a kind of health tea ".The Chinese medicine preparation and the health product of above-mentioned ophthalmics such as all treatment myopia have nothing in common with each other, and therapeutic effect also is not quite similar.In medical practice, in general, that the traditional Chinese medical science is cured the disease is effective, be free from side effects substantially.The inventor also once had " a kind of Chinese medicine preparation for the treatment of near-sighted ophthalmic and preparation method thereof " ZL200410040984.2 number, the Chinese medicine preparation that proposes has certain therapeutic effect to the myope, belong to first generation product, but this patented technology need be improved, and could reach better effect when the treatment myope.
Summary of the invention
Purpose of the present invention just is to provide a kind of Chinese medicine for the treatment of near-sighted ophthalmic, makes the patient can be in shorter anti-, and the vision that is improved obtains better therapeutic effect.
Solution of the present invention is based on the research of inventor at first generation product clinical treatment, examines the pluses and minuses of its original prescription closely, the second filial generation Chinese medicine preparation that develops.
The component and the consumption of the Chinese medicine preparation of the near-sighted ophthalmic of treatment of the present invention are as follows:
80~250 parts of 80~200 parts of Fructus Ligustri Lucidi of 80~200 parts of Radix Salviae Miltiorrhizaes of Semen Cassiae
80~200 parts of 80~200 parts of Radix Adenophoraes of 80~200 portions of Rhizoma Dioscoreaes of Herba Tropaeoli
80~200 parts of 80~200 portions of Fructus Rubies of 50~150 parts of Poria of golden bell core
50~90 parts of 50~150 portions of Herba Lophatheris of 80~200 portions of Fructus Tribulis of Radix Ophiopogonis
80~200 parts of 50~150 parts of Radixs Astragali of 80~200 parts of Fructus Leonuris of Semen Plantaginis
50~150 parts of Ramulus Uncariae macrophyllae
In the above-mentioned Chinese medicine, Semen Cassiae (Cassia tora), bitter but sweet flavor, cool in nature, the effect that liver heat removing is arranged, makes eye bright can be controlled wind heat acute conjunctivitis, optic atrohic blindness, nyctalopia etc. take a disease (see the new medical college in Jiangsu compile " Chinese medicine voluminous dictionary " P949); Radix Salviae Miltiorrhizae (Salvia miltiorrhiza), bitter in the mouth, slightly warm in nature has the effect of promoting blood circulation and stopping pain, can control acute conjunctivitis (seeing " Chinese medicine voluminous dictionary " P480); Fructus Ligustri Lucidi (Ligustrum lucidum), bitter but sweet flavor, property is flat, and the effect of invigorating the liver and kidney is arranged, and materials for improving vision is controlled order flower tinnitus (seeing " Chinese medicine voluminous dictionary " P237); Herba Tropaeoli (Tropaeolum majus), acrid in the mouth, cool in nature, the energy heat-clearing and toxic substances removing can be controlled conjunctival congestion and swelling pain (seeing " Chinese medicine voluminous dictionary " P1124); Rhizoma Dioscoreae (Dioscorea opposita) has another name called Rhizoma Dioscoreae, sweet in the mouth, and property is flat, but normal hearing and eyesight (seeing " Chinese medicine voluminous dictionary " P166) is obeyed in spleen invigorating for a long time; Radix Adenophorae (Ophiopogon japonicus) has another name called the bubble ginseng, and sweet and slightly bitter taste is cool in nature, but nourishing YIN and clearing away lung-heat (seeing " Chinese medicine voluminous dictionary " P1560); Golden bell core (Forsythia suspensa), i.e. Fructus Forsythiae, bitter in the mouth, cool in nature, but heat-clearing and toxic substances removing (seeing " Chinese medicine voluminous dictionary " P1111); Poria (Poria cocos), slightly sweet flavor, property is flat, and the effect (seeing " Chinese medicine voluminous dictionary " P1596) of eliminating dampness and diuresis, happy Fructus Alpiniae Oxyphyllae is arranged; Fructus Rubi (Rubus chingii), sweet in the mouth acid, property is flat, can make eye bright, control order dark (seeing " Chinese medicine voluminous dictionary " P2698) by controlling nocturnal emission with astringent drugs; Radix Ophiopogonis (Ophiopogon japonicus), sweet and slightly bitter taste, property is flat, but nourishing YIN and moistening the lung, the liver benefiting that clears away heart-fire (seeing " Chinese medicine voluminous dictionary " P1024); Fructus Tribuli (Tribulus terrestris), the acrid in the mouth hardship, warm in nature, the wind that can loose makes eye bright, and controls the swollen nebula (seeing " Chinese medicine voluminous dictionary " P1274) of conjunctival congestion; Herba Lophatheri (Lopha therum gracile), slightly sweet flavor, cold in nature, but clearing away heart-fire, heat clearing away and restlessness relieving (seeing " Chinese medicine voluminous dictionary " P2253); Semen Plantaginis (Plantago asiatica), sweet in the mouth, cold in nature, can clearing away heat to improve acuity of vision, can control conjunctival congestion hide from view (seeing " Chinese medicine voluminous dictionary " P403); Fructus Leonuri (Leonurus heterophyllus), i.e. FRUCTUS LEONURI, the bitter but sweet flavor suffering, cool in nature, but wind and heat dispersing is controlled conjunctival congestion and swelling pain, nebula film (seeing " Chinese medicine voluminous dictionary " P1609); The Radix Astragali (Astragalus membranaceus), sweet in the mouth, slightly warm in nature, energy stomach reinforcing consolidating superficial resistance, inducing diuresis to remove edema, invigorating the spleen and replenishing QI (seeing " Chinese medicine voluminous dictionary " P2036); Ramulus Uncariae macrophyllae, i.e. Ramulus Uncariae macrophyllae (Uncaria macrophylla), sweet-bitter flavor, cool in nature, can the heat clearing away suppressing the hyperactive liver, relieving convulsion (seeing " Chinese medicine voluminous dictionary " P142) relieves dizziness, high fever, infantile convulsions, epilepsy, etc.Above-mentioned medical material should meet " the regulation in one one of the Chinese pharmacopoeia nineteen ninety-five version under each medical material item.
Contrast first generation medicine (patent ZL200410040984.2 number) and second filial generation medicine, as can be seen, two generations most medical materials of filling a prescription be identical, but second filial generation prescription has increased the Radix Astragali and Ramulus Uncariae macrophyllae without Semen Sesami Nigrum.This is that if use the treatment by Chinese herbs of first generation prescription, effect is difficult to satisfactory because the inventor explores many patients in medical practice myopia is because its YANG QI deficiency, and the deficiency of vital energy causes.For this reason, the inventor adds the Radix Astragali in prescription, can improve patient's immunocompetence, promotes its visual cell to generate; Add Ramulus Uncariae macrophyllae simultaneously, the help patient dispels the wind, spasmolytic, improves, improves, strengthens the function of eye regulating muscle, finally reaches the effect of lifting vision.
The preparation method of Chinese medicine of the near-sighted ophthalmic of treatment of the present invention is to be equipped with medicine by the Chinese medicine of respectively distinguishing the flavor of in the prescription, and wherein, Rhizoma Dioscoreae and Poria are through cleaning, cure, be ground into fine powder, and be standby; Again the medicinal clear water of 14 flavors such as Semen Cassiae, Radix Salviae Miltiorrhizae, Fructus Ligustri Lucidi, Herba Tropaeoli, Radix Adenophorae, golden bell core, Fructus Rubi, Radix Ophiopogonis, Fructus Tribuli, Herba Lophatheri, Semen Plantaginis, Fructus Leonuri, the Radix Astragali and Ramulus Uncariae macrophyllae is decocted, extract decoction liquor, carry out altogether 3 times, decocted 1 hour at every turn; Then the decoction liquor of extracting is filtered, get its filtrate steaming and decocting and concentrate and make extractum, add standby medicated powder again, mixing; With the conventional method drying, pulverize, sieve, require the medicated powder fineness usually below 1mm, after the assay was approved, can carry out dosage form processing.Usually incapsulate, make the capsule product.Product should meet " requirement in one one of the Chinese pharmacopoeia nineteen ninety-five version, product index is as follows: it is 2.0g that every capsules contains former dose, and content uniformity is at 2.0g ± 10%; Moisture must not surpass 9.0%, and product disintegration is 30 minutes.
The Chinese medicinal formulae of the near-sighted ophthalmic of treatment of the present invention, method that also can be by routine or make powder or add compressed with adhesive to become tablet or make pill or add implant and make electuary etc. and make product by agitation procedure.
The usage of capsule of the present invention is oral, warm water delivery service, every day 3 times, each 2~3.
The Chinese medicinal formulae of the near-sighted ophthalmic of treatment of the present invention is clinical use result show, the effect that this prescription has liver heat removing nourishing the liver, improving kidney and eyes, dispels the wind, spasmolytic, promotion visual cell generate, can promote optic nerve, retina cell reparation, reinforcing glass body steadiness, prevention retina shedding, being used for the treatment of myopia that a variety of causes causes, asthenopia etc. takes a disease, prescription is unique, and curative effect is also unique, especially to child and juvenile patient, evident in efficacy, can make the patient eliminate symptom, recover vision.
The inventor successfully cured many myopes, wherein more typical case has: (1) lives in the girl patient Fu Benjing of Guiyang City, Guizhou Province public security bureau dormitory, the time 8 years old year, suffered from eyes myopia disease in 2003, rise and take the Drug therapy that the present invention makes in October, 2003, and the state of an illness progressively takes a turn for the better, the back vision raising of 11 week of medication, at the beginning of 2004, vision reaches normally substantially, and left eye, right eye all reach 1.2.The phone 0851-5622029 of this patient family.(2) live in the girl Zhang Fangming of No. 402,13 unit of expensive ferrum commercial and residential building, Kweiyang, the time 9 years old 1,2004 year year because of suffering from eyes myopia, through taking the Drug therapy that the present invention makes, the state of an illness takes a turn for the better rapidly, after treatment March, the right and left eyes vision all reaches 1.0.The phone 0851-8134026 of this patient family.(3) live in the girl Chen Lu that the stockaded village is newly added in the Guiyang, the time 11 years old year, in October, 2003 first visit finds to suffer from eyes myopia disease, the images of left and right eyes vision is all less than 1.0, rise in by the end of October, 2003 and take the capsule for treating that the present invention makes, the state of an illness progressively takes a turn for the better, and vision improves after the medication, in mid-January, 2004, eye vision reached 1.2, the basic healing.The phone 0851-6843123 of this patient family.(4) live in the get on well with others boy Cai Jiazhi on Lu Meiyun square of Guiyang, the time 10 years old year, suffer from eyes myopia in November, 2003, visual deterioration 3 years, the images of left and right eyes vision is respectively 0.8/1.5 and 0.3/0.66, and through taking the Drug therapy that the present invention makes, the state of an illness takes a turn for the better rapidly, after treating for 2 15th day of a month, the images of left and right eyes vision reaches 1.2/1.5 and 1.0/1.5.The phone 0851-6577470 of this patient family.
The specific embodiment
Embodiment gets Rhizoma Dioscoreae 122g and Poria 122g through cleaning, cure, be ground into fine powder, and is standby; Again the medicinal clear water of 14 flavors such as Semen Cassiae 122g, Radix Salviae Miltiorrhizae 122g, Fructus Ligustri Lucidi 244g, Herba Tropaeoli 122g, Radix Adenophorae 122g, golden bell core 97g, Fructus Rubi 122g, Radix Ophiopogonis 122g, Fructus Tribuli 97g, Herba Lophatheri 73g, Semen Plantaginis 122g, Fructus Leonuri 97g, Radix Astragali 122g, Ramulus Uncariae macrophyllae 97g is decocted, extract decoction liquor, carry out altogether 3 times, decocted 1 hour at every turn; Then the decoction liquor of extracting is filtered, get its filtrate steaming and decocting and concentrate and make extractum, add standby medicated powder again, mixing; With the conventional method drying, pulverize, sieve, require the medicated powder fineness usually below 1mm, after the assay was approved, the capsule of promptly packing into is made the capsule product.
When the patient takes, every day 3 times, each 2~3.

Claims (3)

1. Chinese medicine for the treatment of near-sighted ophthalmic, contain Semen Cassiae, Radix Salviae Miltiorrhizae, Fructus Ligustri Lucidi, Herba Tropaeoli, Rhizoma Dioscoreae, Radix Adenophorae, golden bell core, Fructus Rubi, Poria, Radix Ophiopogonis, Fructus Tribuli, Herba Lophatheri, Semen Plantaginis, Fructus Leonuri, it is characterized in that this Chinese medicine also contains the Radix Astragali and Ramulus Uncariae Cum Uncis, this Chinese medicine preparation component and consumption are as follows:
80~250 parts of 80~200 parts of Fructus Ligustri Lucidi of 80~200 parts of Radix Salviae Miltiorrhizaes of Semen Cassiae
80~200 parts of 80~200 parts of Radix Adenophoraes of 80~200 portions of Rhizoma Dioscoreaes of Herba Tropaeoli
80~200 parts of 80~200 portions of Fructus Rubies of 50~150 parts of Poria of golden bell core
50~90 parts of 50~150 portions of Herba Lophatheris of 80~200 portions of Fructus Tribulis of Radix Ophiopogonis
80~200 parts of 50~150 parts of Radixs Astragali of 80~200 parts of Fructus Leonuris of Semen Plantaginis
50~150 parts of Ramulus Uncariae macrophyllae.
2. according to the preparation method of the Chinese medicine preparation of the near-sighted ophthalmic of the described treatment of claim 1, it is characterized in that being equipped with medicine by the Chinese crude drug of respectively distinguishing the flavor of in the prescription, wherein, Rhizoma Dioscoreae and Poria are through cleaning, cure, be ground into fine powder, and be standby; Again the medicinal clear water of 14 flavors such as Semen Cassiae, Radix Salviae Miltiorrhizae, Fructus Ligustri Lucidi, Herba Tropaeoli, Radix Adenophorae, golden bell core, Semen Sesami Nigrum, Fructus Rubi, Radix Ophiopogonis, Fructus Tribuli, Herba Lophatheri, Semen Plantaginis, Fructus Leonuri, the Radix Astragali and Ramulus Uncariae macrophyllae is decocted, extract decoction liquor, carry out altogether 3 times, decocted 1 hour at every turn; Then the decoction liquor of extracting is filtered, get its filtrate steaming and decocting and concentrate and make extractum, add standby medicated powder again, mixing; With the conventional method drying, pulverize, sieve, require the medicated powder fineness usually below 1mm, after the assay was approved, promptly can be made into preparation.
3. according to the Chinese medicine of the described treatment amblyopia of claim 1 ophthalmic, it is characterized in that this Chinese medicine can incapsulate, make the capsule product, method that can also be by routine or make powder or add compressed with adhesive to become tablet or make pill or add implant and make electuary and make product by agitation procedure.
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103181431A (en) * 2012-06-06 2013-07-03 严丰丽 Liver-nourishing health protection tea and preparation method
CN104689107A (en) * 2015-02-10 2015-06-10 潘雄峰 Traditional Chinese medicine for treating nearsightedness and preparation method thereof
CN106214992A (en) * 2016-07-08 2016-12-14 贵州宗智医药科技有限公司 A kind of Chinese medicine formula for treating myopia

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CN1268354C (en) * 2004-11-03 2006-08-09 李宗智 Traditional Chinese medicine preparation for treating myopia and method for preparing the same
CN1268353C (en) * 2004-11-03 2006-08-09 李宗智 Traditional Chinese medicine preparation for treating amblyopia and method for preparing the same

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CN1268353C (en) * 2004-11-03 2006-08-09 李宗智 Traditional Chinese medicine preparation for treating amblyopia and method for preparing the same

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103181431A (en) * 2012-06-06 2013-07-03 严丰丽 Liver-nourishing health protection tea and preparation method
CN103181431B (en) * 2012-06-06 2014-09-10 严丰丽 Liver-nourishing health protection tea and preparation method
CN104689107A (en) * 2015-02-10 2015-06-10 潘雄峰 Traditional Chinese medicine for treating nearsightedness and preparation method thereof
CN104689107B (en) * 2015-02-10 2017-12-26 潘雄峰 It is a kind of to be used to treat Chinese medicine composition of myopia and preparation method thereof
CN106214992A (en) * 2016-07-08 2016-12-14 贵州宗智医药科技有限公司 A kind of Chinese medicine formula for treating myopia

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