CN104689107A - Traditional Chinese medicine for treating nearsightedness and preparation method thereof - Google Patents

Traditional Chinese medicine for treating nearsightedness and preparation method thereof Download PDF

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CN104689107A
CN104689107A CN201510073203.8A CN201510073203A CN104689107A CN 104689107 A CN104689107 A CN 104689107A CN 201510073203 A CN201510073203 A CN 201510073203A CN 104689107 A CN104689107 A CN 104689107A
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chinese medicine
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CN104689107B (en
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潘雄峰
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Abstract

The invention relates to a traditional Chinese medicine for treating nearsightedness and a preparation method thereof, relating to the field of traditional Chinese medicines. The traditional Chinese medicine comprises the following raw materials in parts by weight: 10-15 parts of semen cassiae, 10-15 parts of glossy privet fruit, 7-9 parts of chrysanthemum, 5-7 parts of the fruit of Chinese wolfberry, 5-7 parts of semen plantaginis, 5-7 parts of ophiopogon root, 3-5 parts of nacre mother of pearl, 10-15 parts of endothelium corneum gigeriae galli, 10-15 parts of mulberry, 3-5 parts of radix angelicae, 3-5 parts of asarum, 1-3 parts of rehmanniae vaporata, 1-3 parts of codonopsis pilosula, and 5-7 parts of lophatherum gracile. The traditional Chinese medicine for treating nearsightedness provided by the invention has the effects of clearing heat, removing toxicity, soothing liver, regulating vital energy, invigorating circulation of blood and improving eyesight, and is used for treating nearsightedness due to various reasons; therefore, the eyesight of patients can be improved within a short time; and the traditional Chinese medicine is free from toxic and side effect and obvious in treatment effect.

Description

One is used for the treatment of bathomorphic Chinese medicine formula and preparation method thereof
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to one and be used for the treatment of bathomorphic Chinese medicine formula and preparation method thereof.
Background technology
Myopia, names of disease of tcm.Be that eye is regulating under relaxed state, parallel rays is before the refraction back focus of the dioptric system of eye drops on retina.Ancient medical book is early recognized primary disease, is called that order can not hypermetropia, and having another name called can nearly timid disease far away, begins to claim myopia to " order is through great achievement ".By congenital generation, myopic degree the higher person is also known as myopia.The generation of myopia with hereditary, grow, the factors such as environment is relevant, but definite pathogeny is still under study for action.Myopia has the multiple origin cause of formation, such as, due to by the bad myopia caused of eye mode, due to the myopia that heredity causes, due to drug-induced myopia etc.Its sickness rate has the trend risen year by year in recent years, especially juvenile onset rate is more obvious, and there is no good medicine at present, most employing is worn glasses, health-care appliance is treated, adopt operative treatment in severe case, the health care instruments such as the eye-protection instrument sold in the market, physiotherapeutic glasses for myopia, although some effect, but can not cure, and easily recur and increase the weight of the state of an illness; Also have some medicines, effect is bad, and treatment time is long; There is great risk in operative treatment, and sequela is more.Why related drugs on the market and therapeutic equipments do not reach the object of effecting a permanent cure, be because treatment myopia be Huoxue Shugan at all, have left medicine or method that this goes blindly to find treatment myopia eye diseases presentation at all, all can have that effect is bad, relapse rate is high even increases the weight of the adverse consequencess such as the state of an illness.
Summary of the invention
Object of the present invention is exactly have for its sickness rate in recent years the trend risen year by year, especially juvenile onset rate is more obvious, and there is no good medicine at present, most employing is worn glasses, health-care appliance is treated, adopt operative treatment in severe case, the health care instruments such as the eye-protection instrument sold in the market, physiotherapeutic glasses for myopia, although some effect, but can not cure, and easily recur and increase the weight of the state of an illness; Also have some medicines, effect is bad, and treatment time is long; There is great risk in operative treatment, and the deficiency that sequela is more, and provide one to be used for the treatment of bathomorphic Chinese medicine formula, the bathomorphic Chinese medicine formula for the treatment of of the present invention has effect of depressed liver-energy dispersing and QI regulating, blood circulation-activating eyesight-improving, is reached fundamentally treat bathomorphic object by dispersing liver and promoting blood circulation.
The present invention comprises the raw material of following weight portion: Semen Cassiae 10-15 part, Fructus Ligustri Lucidi 10-15 part, Flos Chrysanthemi 7-9 part, Fructus Lycii 5-7 part, Semen Plantaginis 5-7 part, Radix Ophiopogonis 5-7 part, Concha Margaritifera 3-5 part, Endothelium Corneum Gigeriae Galli 10-15 part, Fructus Mori 10-15 part, Radix Angelicae Dahuricae 3-5 part, Herba Asari 3-5 part, Radix Rehmanniae Preparata 1-3 part, Radix Codonopsis 1-3 part, Herba Lophatheri 5-7 part.
Preferably, comprise the raw material of following weight portion: Semen Cassiae 13 parts, Fructus Ligustri Lucidi 13 parts, Flos Chrysanthemi 8 parts, Fructus Lycii 6 parts, Semen Plantaginis 6 parts, Radix Ophiopogonis 6 parts, Concha Margaritifera 4 parts, Endothelium Corneum Gigeriae Galli 13 parts, 13 parts, Fructus Mori, the Radix Angelicae Dahuricae 4 parts, Herba Asari 4 parts, 2 parts, Radix Rehmanniae Preparata, Radix Codonopsis 2 parts, Herba Lophatheri 6 parts.
The preparation method of above-mentioned Chinese medicine formula comprises step below:
(1) by Semen Cassiae, Fructus Ligustri Lucidi, Flos Chrysanthemi, Fructus Lycii, Semen Plantaginis, Radix Ophiopogonis, Concha Margaritifera, Endothelium Corneum Gigeriae Galli, Fructus Mori, the Radix Angelicae Dahuricae, Herba Asari, Radix Rehmanniae Preparata, Radix Codonopsis, Herba Lophatheri first uses 2 ° of-5 ° of cold water soak 5 hours, puts into drying baker and carry out drying after immersion, drying baker temperature controls at 46 °-50 °, and drying time is 20 minutes, for subsequent use after placing room temperature;
(2) get dried Semen Cassiae, Fructus Ligustri Lucidi, Flos Chrysanthemi, Fructus Lycii, Semen Plantaginis grinds, and is ground into 300-400 object micropowder, micropowder is put into the ethanol water filling 75%, and reflux, extract, 5 times, is then concentrated into extractum by extracting solution for subsequent use;
(3) dried Radix Ophiopogonis is got, Concha Margaritifera, Endothelium Corneum Gigeriae Galli, Fructus Mori, the Radix Angelicae Dahuricae, Herba Asari, Radix Rehmanniae Preparata, Radix Codonopsis, Herba Lophatheri is put into container and pounds, keep vessel temp under 30 DEG C of environment, pound to one-tenth graininess, then put into and decoct container, decoct 3 times, each decoction 0.5 hour, then the decoction liquor obtained is filtered, get the filtrate after filtration, to make extractum for subsequent use by concentrated for filtrate steaming and decocting;
(4) by the extractum mix homogeneously that the 2nd step and the 3rd step obtain, then carry out drying, again pulverize as 300-400 object micropowder after drying, make tablet, pill, unguentum after the micropowder obtained is added filler, binding agent or load snap fit capsule.In above-mentioned each Chinese medicine ingredients:
Semen Cassiae, Semen Cassiae, bitter but sweet flavor, cool in nature, have the effect of liver heat removing, improving eyesight, can control wind heat acute conjunctivitis, optic atrohic blindness, nyctalopia etc. and take a disease, be monarch drug.
Fructus Ligustri Lucidi, liver and kidney tonifying, clearind deficient heat, improving eyesight.Cure mainly: Light-headedness, soreness of the waist and knees, seminal emission, early whitening of beard and hair, osteopyrexia and fever, poor vision, the hepatic and renal YIN deficiency is monarch drug.
Flos Chrysanthemi, mildly bitter flavor, property gas peace, having loose wind heat clearing away, effect of suppressing the hyperactive liver improving eyesight, is ministerial drug.
Fructus Lycii, sweet in the mouth, property gas peace, having nourishing kidney, lung moistening, tonifying liver, effect of improving eyesight, is ministerial drug.
Semen Plantaginis, sweet in the mouth, cold nature, has clearing away heat and promoting diuresis, and eliminating dampness by diuresis is treating stranguria, improving eyesight, the effect of eliminating the phlegm, and is ministerial drug.
Radix Ophiopogonis, sweet in the mouth, micro-hardship, cold nature, has YIN nourishing and the production of body fluid promoting, effect that lung moistening clears away heart-fire, and is ministerial drug.
Concha Margaritifera, taste is micro-salty, and cold nature has suppressing the hyperactive liver and subsiding YANG, and effect of arresting convulsion improving eyesight is adjuvant drug.
Endothelium Corneum Gigeriae Galli, sweet in the mouth, property gas peace, having invigorating the stomach and promoting digestion, effect of arresting seminal emission, is adjuvant drug.
Fructus Mori, sweet in the mouth, acid, cold nature, has YIN nourishing of enriching blood, effect of moisturizing of promoting the production of body fluid, and is adjuvant drug.
The Radix Angelicae Dahuricae, acrid in the mouth, warm in nature and, have loose wind dehumidifying, understand things pain-stopping, effect of detumescence and apocenosis is adjuvant drug.
Herba Asari, acrid in the mouth, warm in nature and, having expelling wind and cold, understand things pain-stopping, effect of warming the lung to resolve fluid-retention, is adjuvant drug.
Radix Rehmanniae Preparata, sweet in the mouth, warm in nature and, there is the effect of YIN nourishing of enriching blood, for making medicine.
Radix Codonopsis, sweet in the mouth, property gas peace, has invigorating the spleen and replenishing QI, effect of spleen invigorating lung benefiting, for making medicine.
Herba Lophatheri, sweet in the mouth, cold nature, has clearing heat and relieving fidgetness, effect of diuresis, for making medicine.
Advantage of the present invention is:
The present invention can provide one to treat bathomorphic Chinese medicine formula, there is effect of heat-clearing and toxic substances removing, depressed liver-energy dispersing and QI regulating, blood circulation-activating eyesight-improving, be used for the treatment of the myopia that a variety of causes causes, patient can be improved vision at short notice, have no side effect, therapeutic effect is remarkable.
Detailed description of the invention
The present invention comprises the raw material of following weight portion: Semen Cassiae 10-15 part, Fructus Ligustri Lucidi 10-15 part, Flos Chrysanthemi 7-9 part, Fructus Lycii 5-7 part, Semen Plantaginis 5-7 part, Radix Ophiopogonis 5-7 part, Concha Margaritifera 3-5 part, Endothelium Corneum Gigeriae Galli 10-15 part, Fructus Mori 10-15 part, Radix Angelicae Dahuricae 3-5 part, Herba Asari 3-5 part, Radix Rehmanniae Preparata 1-3 part, Radix Codonopsis 1-3 part, Herba Lophatheri 5-7 part.
Embodiment 1:
Preferably, comprise the raw material of following weight portion: Semen Cassiae 13 parts, Fructus Ligustri Lucidi 13 parts, Flos Chrysanthemi 8 parts, Fructus Lycii 6 parts, Semen Plantaginis 6 parts, Radix Ophiopogonis 6 parts, Concha Margaritifera 4 parts, Endothelium Corneum Gigeriae Galli 13 parts, 13 parts, Fructus Mori, the Radix Angelicae Dahuricae 4 parts, Herba Asari 4 parts, 2 parts, Radix Rehmanniae Preparata, Radix Codonopsis 2 parts, Herba Lophatheri 6 parts.
Concrete preparation method following steps:
(1) by Semen Cassiae, Fructus Ligustri Lucidi, Flos Chrysanthemi, Fructus Lycii, Semen Plantaginis, Radix Ophiopogonis, Concha Margaritifera, Endothelium Corneum Gigeriae Galli, Fructus Mori, the Radix Angelicae Dahuricae, Herba Asari, Radix Rehmanniae Preparata, Radix Codonopsis, Herba Lophatheri first uses 2 ° of-5 ° of cold water soak 5 hours, puts into drying baker and carry out drying after immersion, drying baker temperature controls at 46 °-50 °, and drying time is 20 minutes, for subsequent use after placing room temperature;
(2) get dried Semen Cassiae, Fructus Ligustri Lucidi, Flos Chrysanthemi, Fructus Lycii, Semen Plantaginis grinds, and is ground into 300-400 object micropowder, micropowder is put into the ethanol water filling 75%, and reflux, extract, 5 times, is then concentrated into extractum by extracting solution for subsequent use;
(3) dried Radix Ophiopogonis is got, Concha Margaritifera, Endothelium Corneum Gigeriae Galli, Fructus Mori, the Radix Angelicae Dahuricae, Herba Asari, Radix Rehmanniae Preparata, Radix Codonopsis, Herba Lophatheri is put into container and pounds, keep vessel temp under 30 DEG C of environment, pound to one-tenth graininess, then put into and decoct container, decoct 3 times, each decoction 0.5 hour, then the decoction liquor obtained is filtered, get the filtrate after filtration, to make extractum for subsequent use by concentrated for filtrate steaming and decocting;
(4) by the extractum mix homogeneously that the 2nd step and the 3rd step obtain, then carry out drying, again pulverize as 300-400 object micropowder after drying, make tablet, pill, unguentum after the micropowder obtained is added filler, binding agent or load snap fit capsule.Clinical observation on the therapeutic effect
1, physical data
Selection of clinical Patients with 300 Cases, wherein man 150 example, female 150 example, wherein 10-15 year 75 example, 15-25 year 75 example, 25-35 year 75 example, 35-45 year 75 example.
2, diagnostic criteria
Effective: vision improves fast, observe 3 months without bounce-back person.
Take a turn for the better: vision slightly improves, and can maintain in existing vision level and do not worsen.
Invalid: invalid after taking medicine.
3, Therapeutic Method
Adopt the capsule made of embodiment 1, every containing crude drug 1g, every day is early, middle and late respectively takes one to patient, within 15 days, is a course for the treatment of, minimumly takes 3 courses for the treatment of.
4, therapeutic outcome
Carry out for 300 routine clinical samples the medicine that Chinese medicine formula of the present invention makes to treat, therapeutic effect is as follows:
Clinical samples total number of persons: 300 people
Treatment time Effective number Improvement number Invalid number Inefficiency
3 courses for the treatment of 280 150 5 1.7%
6 courses for the treatment of 290 250 3 1%
Carry out drug withdrawal observation in 2 years to the clinical samples that 200 routine therapeutic effect take a turn for the better, recurrence is as follows:
Withdrawal time The unchanged number of vision Recurrence number Untoward reaction number Relapse rate
2 years 190 9 1 4.5%
Model case is as follows:
Case 1, Liu, man 15 years old, suffer from high myopia, object at the moment cannot be seen clearly, after using 3 courses for the treatment of of product of embodiment 1, can obviously feel that vision improves, after continuing 6 courses for the treatment of of use, vision restoration is to 1.0, drug withdrawal 2 years, anopsia bounce-back sign, has no adverse reaction.
Case 2, together certain, female 24 years old, two eye visions are 0.5, once use laser surgery treatment mistake before, but vision bounce-back after a year, vision gets back to 0.5 again, and after using 3 courses for the treatment of of product of embodiment 1, vision restoration is to 0.8, after continuing 6 courses for the treatment of of use, vision restoration is to 1.2, and drug withdrawal 2 years, do not rebound sign.
Case 3, become certain, female 35 years old, binocular vision 0.4, continue nearly 25 years of myopia, tried the bathomorphic medicine of various treatment, all without positive effect, after 10 courses for the treatment of of product of use embodiment 1, binocular vision all reaches 0.8, at present still in the treatment.
Certainly; the present invention can also have other various embodiments; when not deviating from the present invention's spirit and essence thereof, those of ordinary skill in the art are when making various corresponding change and distortion according to the present invention, but these change accordingly and distortion all should belong to protection scope of the present invention.

Claims (3)

1. be used for the treatment of a bathomorphic Chinese medicine formula, comprise the raw material of following weight portion: Semen Cassiae 10-15 part, Fructus Ligustri Lucidi 10-15 part, Flos Chrysanthemi 7-9 part, Fructus Lycii 5-7 part, Semen Plantaginis 5-7 part, Radix Ophiopogonis 5-7 part, Concha Margaritifera 3-5 part, Endothelium Corneum Gigeriae Galli 10-15 part, Fructus Mori 10-15 part, Radix Angelicae Dahuricae 3-5 part, Herba Asari 3-5 part, Radix Rehmanniae Preparata 1-3 part, Radix Codonopsis 1-3 part, Herba Lophatheri 5-7 part.
2. one according to claim 1 is used for the treatment of bathomorphic Chinese medicine formula, comprises the raw material of following weight portion: Semen Cassiae 13 parts, Fructus Ligustri Lucidi 13 parts, Flos Chrysanthemi 8 parts, Fructus Lycii 6 parts, Semen Plantaginis 6 parts, Radix Ophiopogonis 6 parts, Concha Margaritifera 4 parts, Endothelium Corneum Gigeriae Galli 13 parts, 13 parts, Fructus Mori, the Radix Angelicae Dahuricae 4 parts, Herba Asari 4 parts, 2 parts, Radix Rehmanniae Preparata, Radix Codonopsis 2 parts, Herba Lophatheri 6 parts.
3. be used for the treatment of a preparation method for bathomorphic Chinese medicine formula as claimed in claim 1 or 2, it is characterized in that comprising step below:
(1) by Semen Cassiae, Fructus Ligustri Lucidi, Flos Chrysanthemi, Fructus Lycii, Semen Plantaginis, Radix Ophiopogonis, Concha Margaritifera, Endothelium Corneum Gigeriae Galli, Fructus Mori, the Radix Angelicae Dahuricae, Herba Asari, Radix Rehmanniae Preparata, Radix Codonopsis, Herba Lophatheri first uses 2 ° of-5 ° of cold water soak 5 hours, puts into drying baker and carry out drying after immersion, drying baker temperature controls at 46 °-50 °, and drying time is 20 minutes, for subsequent use after placing room temperature;
(2) get dried Semen Cassiae, Fructus Ligustri Lucidi, Flos Chrysanthemi, Fructus Lycii, Semen Plantaginis grinds, and is ground into 300-400 object micropowder, micropowder is put into the ethanol water filling 75%, and reflux, extract, 5 times, is then concentrated into extractum by extracting solution for subsequent use;
(3) dried Radix Ophiopogonis is got, Concha Margaritifera, Endothelium Corneum Gigeriae Galli, Fructus Mori, the Radix Angelicae Dahuricae, Herba Asari, Radix Rehmanniae Preparata, Radix Codonopsis, Herba Lophatheri is put into container and pounds, keep vessel temp under 30 DEG C of environment, pound to one-tenth graininess, then put into and decoct container, decoct 3 times, each decoction 0.5 hour, then the decoction liquor obtained is filtered, get the filtrate after filtration, to make extractum for subsequent use by concentrated for filtrate steaming and decocting;
(4) by the extractum mix homogeneously that the 2nd step and the 3rd step obtain, then carry out drying, again pulverize as 300-400 object micropowder after drying, make tablet, pill, unguentum after the micropowder obtained is added filler, binding agent or load snap fit capsule.
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CN110179890A (en) * 2019-07-05 2019-08-30 于丽文 A kind of prevention and treatment myopia and its Chinese medicine composition of complication and preparation method thereof

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CN110179890A (en) * 2019-07-05 2019-08-30 于丽文 A kind of prevention and treatment myopia and its Chinese medicine composition of complication and preparation method thereof

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