CN104069424B - Traditional Chinese medicine for treating alzheimer disease and preparation method thereof - Google Patents
Traditional Chinese medicine for treating alzheimer disease and preparation method thereof Download PDFInfo
- Publication number
- CN104069424B CN104069424B CN201410140646.XA CN201410140646A CN104069424B CN 104069424 B CN104069424 B CN 104069424B CN 201410140646 A CN201410140646 A CN 201410140646A CN 104069424 B CN104069424 B CN 104069424B
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- preparation
- chinese medicine
- crude drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The invention discloses a traditional Chinese medicine for treating alzheimer disease and a preparation method thereof. The traditional Chinese medicine for treating alzheimer disease is prepared from the following raw medicinal materials in parts by weight: 5-20 parts of morinda officinalis, 5-20 parts of rhizoma acori graminei, 5-30 parts of radix curcumae, 5-30 parts of radix astragali and 1-20 parts of radix polygalae. The invention provides a preparation method of the traditional Chinese medicine for treating alzheimer disease, comprising the following steps: (1) weighing the raw medicinal materials in proportions for later use; (2) adding water to the raw medicinal materials for soaking, heating, decocting, filtering, adding water to decoction dregs again, heating, decocting, filtering and combining filtrates to obtain a supernate; and (3) concentrating the supernate, drying till medicine liquid is in a powder form to prepare a preparation. Through reasonable proportioning and synergistic effects of the medicinal materials, the traditional Chinese medicine has obvious curative effects on improvement of clinical symptoms of alzheimer disease and can be taken for a long period of time.
Description
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of Chinese medicine with treatment Alzheimer and its preparation side
Method.
Background technology
Alzheimer（Alzheimer disease, AD）It is a kind of neural degeneration with progressive dementia as performance
Pathological changes.With population in the world aging, AD sickness rate constantly rises.According to statistics, the whole world crowd of 65～69 years old about 1% suffers from
AD, the prevalence about 45% of more than 85 years old old man.The AD prevalences 4.8% of China, and have ever-increasing trend, and treat
Effect is unsatisfactory.Therefore the medicine for researching and developing effectively treatment Alzheimer is very urgent.
The medicine for the treatment of Alzheimer mainly has the therapy of the selective agonist Antioxidation Treatment of receptor etc., right
It is undesirable in the therapeutic effect of middle severe AD.
Although having applied for numerous patents in terms for the treatment of Alzheimer in prior art, current still needleless
There is the medicine of good therapeutic effect to Alzheimer.
The content of the invention
The brief overview with regard to the present invention is given below, to provide the basic reason with regard to certain aspects of the invention
Solution.It should be appreciated that this general introduction is not the exhaustive general introduction with regard to the present invention.It is not intended to determine the key of the present invention
Or pith, nor is it intended to limit the scope of the present invention.Its purpose only provides some concepts in simplified form, with
This is used as the preamble in greater detail discussed after a while.
The purpose of the embodiment of the present invention is the defect for above-mentioned prior art, there is provided a kind of to treating Alzheimer
There is the Chinese medicine of clear and definite therapeutical effect.
The present invention also provides a kind of preparation method of the Chinese medicine with treatment Alzheimer.
To achieve these goals, the present invention is adopted the technical scheme that：
A kind of Chinese medicine with treatment Alzheimer, is made up of the crude drug of following weight portion：
Radix Morindae Officinaliss 5-20, Rhizoma Acori Graminei 5-20 parts, Radix Curcumae 5-30 parts, Radix Astragali 5-30 parts, Radix Polygalae 1-20 part.
The invention provides a kind of preparation method of the Chinese medicine with treatment Alzheimer, comprises the following steps：
（1）By proportioning, each crude drug is weighed standby；
（2）To adding water immersion, heating to decoct in crude drug, filter, medicinal residues add water, heating is decocted, and is filtered, filtrate
Merge, obtain supernatant；
（3）After supernatant concentration, it is dried, it is powdered to medicinal liquid, it is prepared into preparation.
The each compositionss of Chinese medicine for having functions that to treat Alzheimer effect of the present invention：
Radix Morindae Officinaliss：Acrid in the mouth, it is sweet；Slightly warm in nature, return through：Kidney channel, Liver Channel.Function：Reinforcing the kidney and supporting YANG；Bone and muscle strengthening；Expelling wind and removing dampness.
《Book on Chinese herbal medicine is looked for the truth》：Radix Morindae Officinaliss, are referred to as the kidney invigorating according to book and want agent, can control infirmities and diseases, and reinforcing YIN-essence benefit essence, with its body profit event ear.
Rhizoma Acori Graminei：Acrid in the mouth, hardship, it is warm in nature.Return through：The heart, stomach.Function dampness elimination appetizing, eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae,《Book on Chinese herbal medicine
It is standby to want》：" the tonifying liver benefit heart, dries by wind, expectorant removing food stagnancy, and whet the appetite alleviating distention in middle-JIAO.Treatment is kept silent a mouthful fulminant dysentery, migratory arthralgia infantile convulsion." modern study is to changing
Learn the effect that the amnemonic improvement result scopolamine of medicine induced mice causes memory acquisition disturbance.
Radix Curcumae：Acrid in the mouth, hardship, it is cold in nature.Return through：Liver, the heart, lung meridian, function：Promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, clear away heart-fire removing heat from blood, profit
Gallbladder jaundice eliminating.For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy are gone mad, jaundice urine is red.《Detailed outline》：Control the vim and vigour heart
Stomachache, puerperal, alienation caused by lochioschesis was intended to extremely, lose heart mania.
The Radix Astragali：Sweet in the mouth, slightly warm in nature.Return through：Return lung, spleen, liver and kidney channel.《Bencao Jingshu》：" function reality table；Gas can be helped；Energy
Interior plug, tonifying for the deficiency can YANG invigorating.
Radix Polygalae：It is bitter, pungent, tepor.GUIXIN, kidney, lung meridian.Function：Tranquilize the mind and promote the intelligence, eliminating the phlegm, insomnia and dreamful sleep of subsiding a swelling are forgetful frightened
Throb with fear, staring spells.Insomnia and dreamful sleep, severe palpitation are forgetful.Epilepsy mania and irritation, spasm are twitched, skin sore.《Sheng Nong's herbal classic》：It is main
Cough with dyspnea damaging the spleen and stomach, tonifying for the deficiency, remove pathogenic factor, sharp nine orifices, Fructus Alpiniae Oxyphyllae are intelligent, and normal hearing and eyesight is not forgotten, strong will times power.
Compared with prior art, the invention has the beneficial effects as follows：
In the Chinese medicine of the present invention, crude drug used is under guidance of traditional Chinese medicine theory, for improving Alzheimer institute
Caused range of clinical symptom, with QI invigorating, kidney tonifying, wind-dispelling as Therapeutic Method, reaching improves the clinical symptoms of Alzheimer
Purpose.Rational proportion of the present invention by each medical material, synergism, the clinical symptoms to improving Alzheimer have clearly
Curative effect, can be with long-term taking.
Specific embodiment
For making purpose, technical scheme and the advantage of the embodiment of the present invention clearer, below in the embodiment of the present invention
Technical scheme is clearly and completely described, it is clear that described embodiment is a part of embodiment of the invention, rather than entirely
The embodiment in portion.The element for describing in one embodiment of the invention and feature can be with one or more embodiments
In the element that illustrates and feature combine.It should be noted that for purposes of clarity, eliminate in explanation it is unrelated to the invention,
Part known to persons of ordinary skill in the art and the expression for processing and description.Based on the embodiment in the present invention, this area is general
The every other embodiment obtained under the premise of creative work is not paid by logical technical staff, belongs to present invention protection
Scope.
The present invention provides a kind of Chinese medicine with treatment Alzheimer, is made up of the crude drug of following weight portion：
Radix Morindae Officinaliss 5-20, Rhizoma Acori Graminei 5-20 parts, Radix Curcumae 5-30 parts, Radix Astragali 5-30 parts, Radix Polygalae 1-20 part.
The different Chinese medicine monomer of present invention research screening, single medicine, compound recipe, under guidance of traditional Chinese medicine theory and by modern section
The research of means is ground, by the rational proportion of each medical material, synergism, has clearly treatment to make to treating Alzheimer
With.
In order to reach more preferable effect, preferred embodiments of the present invention：Chinese medicine with treatment Alzheimer, by following
The crude drug of weight portion is made：
Radix Morindae Officinaliss 10-15, Rhizoma Acori Graminei 10-15 parts, Radix Curcumae 15-20 parts, Radix Astragali 15-20 parts, Radix Polygalae 5-15 part.
In order to reach more preferable effect, the preferred scheme of the present invention：Chinese medicine composition with treatment Alzheimer
Thing, is made up of the crude drug of following weight portion：
Radix Morindae Officinaliss 10,15 parts of Rhizoma Acori Graminei, 15 parts of Radix Curcumae, 20 parts of the Radix Astragali, 10 parts of Radix Polygalae.
The present invention also provides the preparation method of the Chinese medicine with treatment Alzheimer, comprises the following steps：
（1）By proportioning, each crude drug is weighed standby；
（2）To adding water immersion, heating to decoct in crude drug, filter, medicinal residues add water, heating is decocted, and is filtered, filtrate
Merge, obtain supernatant；
（3）After supernatant concentration, it is dried, it is powdered to medicinal liquid, preparation is prepared into according to prior art.
The preparation method of the present invention is simple, and each crude drug is natural material, and human body is had no side effect.
In order that to Chinese medicine there is more preferable effect, it is preferable that the step（2）Including：Add in the crude drug
The amount for entering water is 8-10 times of crude drug gross weight, and soak time is 1-2 hours, heats 90-100 DEG C, and it is little that heating decocts 1-1.5
When；The amount for adding water in the medicinal residues is 6-8 times of crude drug gross weight, and soak time is 0.5-1 hours, heats 90-100
DEG C, heating decocts 0.5-1 hours.
In order to reach more preferable drying effect, the step（3）Including：
When the supernatant concentration to relative density is 1.05-1.08, it is put into exsiccator and is dried, baking temperature 80-
100℃。
The preparation of the present invention can add various adjuvants as needed, and being prepared using the conventional method of Chinese medicine preparation becomes piece
Agent, granule, capsule, pill, powder, soft extract, syrup or oral liquid.
Below by specific embodiment, the present invention is further illustrated：
Embodiment 1
Crude drug is weighed according to following weight（g）：
Radix Morindae Officinaliss 10, Rhizoma Acori Graminei 15, Radix Curcumae 15, the Radix Astragali 20, Radix Polygalae 10.
The preparation method of Tablets：
After Radix Morindae Officinaliss 10g, Rhizoma Acori Graminei 15g, Radix Curcumae 15g, Radix Astragali 20g and Radix Polygalae 10g are weighed according to proportioning, raw material is added
The water of 9 times of amounts of medicine gross weight soaks 1.5 hours, is heated to 100 DEG C, decocts 1.5 hours, filters, and it is total that medicinal residues add crude drug
The water of 7 times of amounts of weight, is heated to 100 DEG C, decocts 1 hour, filters, and filtrate merges, and obtains supernatant；Supernatant concentration is to relative
When density is 1.06, it is put into exsiccator and is dried, baking temperature is 100 DEG C, powdered to medicinal liquid, by above-mentioned powder by normal
Rule technique, adds adjuvant to make granule, and re-dry, tabletting obtain final product tablet.Specification：3g/ pieces.
Usage and dosage：1-3 pieces, daily 2-3 time every time.
Embodiment 2
Crude drug is weighed according to following weight（g）：
Radix Morindae Officinaliss 15, Rhizoma Acori Graminei 10, Radix Curcumae 20, the Radix Astragali 15, Radix Polygalae 5.
The preparation method of capsule of the present invention：
After Radix Morindae Officinaliss 15g, Rhizoma Acori Graminei 10g, Radix Curcumae 20g, Radix Astragali 15g and Radix Polygalae 5g are weighed according to proportioning, raw material is added
The water of 8 times of amounts of medicine gross weight soaks 1 hour, is heated to 90 DEG C, decocts 1 hour, filters, and medicinal residues add crude drug gross weight
The water of 6 times of amounts, is heated to 95 DEG C, decocts 0.5 hour, filters, and filtrate merges, and obtains supernatant；Supernatant concentration is to relative density
For 1.05 when, be put into exsiccator and be dried, baking temperature is 80 DEG C, powdered to medicinal liquid, by above-mentioned powder routinely work
Skill adds adjuvant, mixes loading gelatine capsule.Specification：3g/ grains.
Usage and dosage：2-3 grains, daily 1-2 time every time.
Embodiment 3
Crude drug is weighed according to following weight（g）：
Radix Morindae Officinaliss 12, Rhizoma Acori Graminei 13, Radix Curcumae 18, the Radix Astragali 17, Radix Polygalae 15.
The preparation method of granule of the present invention：
After Radix Morindae Officinaliss 12g, Rhizoma Acori Graminei 13g, Radix Curcumae 18g, Radix Astragali 17g and Radix Polygalae 15g are weighed according to proportioning, raw material is added
The water of 10 times of amounts of medicine gross weight soaks 1.3 hours, is heated to boiling, decocts 1.3 hours, filters, and it is total that medicinal residues add crude drug
The water of 8 times of amounts of weight, is heated to 90 DEG C, decocts 0.7 hour, filters, and filtrate merges, and obtains supernatant；Supernatant concentration is to phase
To density be 1.08 when, be put into exsiccator and be dried, baking temperature be 90 DEG C, it is powdered to medicinal liquid, above-mentioned powder is pressed
Common process, adds adjuvant to make granule, obtains final product granule.Specification：6g/ bags.
Usage and dosage：It is 1 bag every time, daily 1-2 time.
Embodiment 4
Crude drug is weighed according to following weight（g）：
Radix Morindae Officinaliss 5,20 parts of Rhizoma Acori Graminei, Radix Curcumae 5, the Radix Astragali 30, Radix Polygalae 1.
After Radix Morindae Officinaliss 5g, stone Chang 20g, Radix Curcumae 5g, Radix Astragali 30g and Radix Polygalae 1g are weighed according to proportioning, add crude drug total
The water of 10 times of amounts of weight soaks 1.5 hours, is heated to 95 DEG C, decocts 1.2 hours, filters, and medicinal residues add crude drug gross weight
7 times amount water, be heated to boiling, decoct 0.8 hour, filter, filtrate merge, obtain supernatant；Supernatant concentration is to relatively close
Spend for 1.07 when, be put into exsiccator and be dried, baking temperature be 95 DEG C, it is powdered to medicinal liquid, in powder add distillation
Water dissolution is medicinal liquid, adds with pleasantly sweet adjuvant, obtains final product oral liquid.Specification：10ml/ bottles.
Usage and dosage：1 bottle every time, 2 times a day.
Embodiment 5
Crude drug is weighed according to following weight（g）
Radix Morindae Officinaliss 20, Rhizoma Acori Graminei 5, Radix Curcumae 30, the Radix Astragali 5, Radix Polygalae 20.
The preparation method of the present embodiment and usage and dosage are same as Example 1.
The clinical experiment of the present invention：
Evaluation treatment by Chinese herbs of the invention is light, the effectiveness and reliability of moderate Alzheimer's disease.
Select that mini-mental state examination (MMSE) is light, moderate AD patients 60, be randomly divided into treatment group and
Matched group is each 30, and treatment group gives the tablet of the preparation of the embodiment of the present invention 1, respectively takes 3g medicines sooner or later daily, and matched group is given
Piracetam is given, 3g medicines is respectively taken sooner or later daily, treatment group and matched group are taken 6g medicines respectively altogether in one day, serve on 12
Week, and observe 12 weeks.
Mini-mental state examination MMSE, daily living measuring scale (ADL) is applied to evaluate and face before and after treatment
Bed curative effect；Untoward reaction is evaluated with untoward reaction scale (TESS).
As a result observe 12 weeks, Tablets treatment group is obviously improved (P compared with matched group MMES, ADL scoring<0.01)；Control
Before treatment group is relatively treated after treating 12 weeks, MMSE and ADL fractions improve respectively（P<0.05, P<0.01)；Tablets treatment group is not
Good response light, compares 2 groups of difference nonsignificance (P with piracetam matched group>0.05), it is shown in Table 1.
Conclusion：Tablets energy effectively treatment is light, moderate AD patients, and the cognitive function to patient and daily life are taken care of oneself
Ability has improvement, and better tolerance is safe.
Table 1 is treated front MMSE, daily living measuring scale (ADL) and evaluates (mean ± s point)
2 groups are compared, the not statistically significant (P of MMSE and ADL differences>0.05)
After treatment, 2 groups of MMSE scorings to be compared and have apparent raising compared with matched group MMSE scorings after Tablets are treated 12 weeks
(P<0.01, it is shown in Table 2);Tablets treatment group Self-controlled study, treatment have apparent raising before relatively treating after 12 weeks,
MMSE fractions improve (P<0.01, it is shown in Table 3)
Scale score result (mean ± s point) after the treatment 12 weeks of 22 groups of table
2 groups are compared, the not statistically significant * * P of MMSE and ADL differences<0.01
Appraisal result (mean ± s point) before the treatment of 3 Tablets of table and after treatment 12 weeks
Tablets own control P<0.01
Untoward reaction：Evaluated with untoward reaction scale (TESS), 4 (13.3%) in treatment group, 2 in matched group
(10.0%) there is the slight untoward reaction such as dizziness, mild diarrhea, nervous, inappetence, do not affect to continue medication or continue medication
Reaction disappears afterwards, does not find death or serious adverse reaction.2 groups of no significant difference (P>0.05).All patient medications
After have no that blood, routine urinalysis and Liver and kidney function change.
Typical clinical experiment example of the invention：
Lee, female are 71 years old, ill 4 years, patient's advanced dementia, and in keeping silent completely, long-term bed, forfeiture are taken care of oneself
Ability, emotion control power are weaker, and the mental status is unstable.The medicine of the embodiment of the present invention 1 is taken, after 1 month, emotion can control
And have verbalization, after taking 3 months, life can be taken care of oneself substantially, and memory is recovered, and the mental status preferably, can be normal with people
Exchange.
Zhang, man, 67 years old, ill 3 years, hypomnesis, outgoing Jing were often got lost, and do not recognize the looks that friend understands relatives,
Also forget their name, it is impossible to normally talk with people, Jing often murmurs to oneself.Take the medicine of the embodiment of the present invention 2,1
After month, memory is clearly better, and can remember name and looks, and after taking 2 months, memory is recovered, and the mental status is good, and energy
Normally talk with people.
Poplar, man, 60 years old, ill 2 years, especially forgetful, the telephone number of oneself was not always remembered, the thing oneself put, and was turned
Where body is just forgotten to be placed on, and computing power declines, and fairly simple account is counted and comes very laborious.The medicine of the embodiment of the present invention 3 is taken,
After two weeks, a symptom takes a turn for the better, and after taking 1 month, hypermnesia can remember telephone number, and simple calculating speed is fast.
In the various embodiments described above of the present invention, the sequence number of embodiment is merely convenient of description, does not represent the quality of embodiment.It is right
The description of each embodiment all emphasizes particularly on different fields, and does not have the part described in detail, may refer to the phase of other embodiment in certain embodiment
Close description.
In the embodiments such as apparatus and method of the present invention, it is clear that each part or each step can be decompose, combination and/
Or reconfigure after decomposing.These decompose and/or reconfigure should be regarded as the present invention equivalents.Meanwhile, it is right above
In the description of the specific embodiment of the invention, the feature for describing for a kind of embodiment and/or illustrating can be with same or like
Mode used in one or more other embodiments, it is combined with the feature in other embodiment, or substitute which
Feature in its embodiment.
It should be emphasized that term "comprises/comprising" refers to the presence of feature, key element, step or component when using herein, but and
It is not excluded for the presence of one or more further features, key element, step or component or additional.
Finally it should be noted that：Although the present invention and its advantage has below been described in detail it should be appreciated that not
Can carry out in the case of the spirit and scope of the present invention being defined by the claims appended hereto various changes, replacement and
Conversion.And, the scope of the present invention is not limited only to the concrete reality of the process described by description, equipment, means, method and steps
Apply example.One of ordinary skilled in the art will readily appreciate that from the disclosure, can be used according to the present invention and be held
The row function essentially identical to corresponding embodiment described herein obtains result, the existing and future essentially identical with which
Process to be developed, equipment, means, method or step.Therefore, appended claim is directed at wrapping in the range of them
Include such process, equipment, means, method or step.
Claims (7)
1. it is a kind of with the Chinese medicine for treating Alzheimer, it is characterised in that to be made up of the crude drug of following weight portion：
Radix Morindae Officinaliss 5-20 parts, Rhizoma Acori Graminei 5-20 parts, Radix Curcumae 5-30 parts, Radix Astragali 5-30 parts, Radix Polygalae 1-20 part.
2. it is as claimed in claim 1 that there is the Chinese medicine for treating Alzheimer, it is characterised in that by the original of following weight portion
Material medicine is made：
Radix Morindae Officinaliss 10-15 parts, Rhizoma Acori Graminei 10-15 parts, Radix Curcumae 15-20 parts, Radix Astragali 15-20 parts, Radix Polygalae 5-15 part.
3. it is as claimed in claim 2 that there is the Chinese medicine for treating Alzheimer, it is characterised in that by the original of following weight portion
Material medicine is made：
10 parts of Radix Morindae Officinaliss, 15 parts of Rhizoma Acori Graminei, 15 parts of Radix Curcumae, 20 parts of the Radix Astragali, 10 parts of Radix Polygalae.
4. the preparation method of the Chinese medicine with treatment Alzheimer as described in any one of claim 1-3, its feature exists
In comprising the following steps：
（1）By proportioning, each crude drug is weighed standby；
（2）To adding water immersion, heating to decoct in crude drug, filter, medicinal residues add water, heating is decocted, and is filtered, and filtrate is closed
And, obtain supernatant；
（3）After supernatant concentration, it is dried, it is powdered to medicinal liquid, it is prepared into preparation.
5. preparation method as claimed in claim 4, it is characterised in that the step（2）Including：Water is added in the crude drug
Amount be 8-10 times of crude drug gross weight, soak time is 1-2 hours, heats 90-100 DEG C, heating decoction 1-1.5 hours；
The amount for adding water in the medicinal residues is 6-8 times of crude drug gross weight, and soak time is 0.5-1 hours, heats 90-100 DEG C, plus
Heat decocts 0.5-1 hours.
6. preparation method as claimed in claim 5, it is characterised in that the step（3）Including：
When the supernatant concentration to relative density is 1.05-1.08, it is put into exsiccator and is dried, baking temperature 80-100
℃。
7. the preparation method as described in any one of claim 4-6, it is characterised in that
The preparation is tablet, granule, capsule, pill, powder, soft extract, syrup or oral liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410140646.XA CN104069424B (en) | 2014-04-09 | 2014-04-09 | Traditional Chinese medicine for treating alzheimer disease and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410140646.XA CN104069424B (en) | 2014-04-09 | 2014-04-09 | Traditional Chinese medicine for treating alzheimer disease and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104069424A CN104069424A (en) | 2014-10-01 |
| CN104069424B true CN104069424B (en) | 2017-03-22 |
Family
ID=51591290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410140646.XA Active CN104069424B (en) | 2014-04-09 | 2014-04-09 | Traditional Chinese medicine for treating alzheimer disease and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104069424B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105878649A (en) * | 2016-04-18 | 2016-08-24 | 易旭 | Pharmaceutical composition for treating AD (Alzheimer's disease) and preparation method of pharmaceutical composition |
| CN106177012A (en) * | 2016-07-01 | 2016-12-07 | 雷大鹏 | A kind of capsule preventing and treating Alzheimer |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1857666A (en) * | 2006-03-14 | 2006-11-08 | 王信锁 | Chinese medicine preparation for treating senile dementia |
| KR20090083780A (en) * | 2008-01-30 | 2009-08-04 | 주식회사 유비오스랩 | A pharmaceutical composition for the treatment and prophylaxis of dementia comprising a ginsenoside-f2 and a ginsenoside-ck |
| CN102895432A (en) * | 2011-07-26 | 2013-01-30 | 王登之 | Prescription and preparation method of rejoicing powder having new dosage form |
-
2014
- 2014-04-09 CN CN201410140646.XA patent/CN104069424B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1857666A (en) * | 2006-03-14 | 2006-11-08 | 王信锁 | Chinese medicine preparation for treating senile dementia |
| KR20090083780A (en) * | 2008-01-30 | 2009-08-04 | 주식회사 유비오스랩 | A pharmaceutical composition for the treatment and prophylaxis of dementia comprising a ginsenoside-f2 and a ginsenoside-ck |
| CN102895432A (en) * | 2011-07-26 | 2013-01-30 | 王登之 | Prescription and preparation method of rejoicing powder having new dosage form |
Non-Patent Citations (1)
| Title |
|---|
| 阿尔兹海默病临床治疗的研究进展;刘国艳等;《中国实用医药》;20140320;第9卷(第8期);第258-259页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104069424A (en) | 2014-10-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104435837B (en) | A kind of pharmaceutical composition for treating spontaneous perspiration, night sweat | |
| CN103784573B (en) | Chinese herbal medicine formula for treating pseudomyopia and producing method thereof | |
| CN101269174A (en) | Pharmaceutical composition for improving memory disturbance senile dementia and preparation method thereof | |
| CN104069424B (en) | Traditional Chinese medicine for treating alzheimer disease and preparation method thereof | |
| CN104524481B (en) | A kind of Chinese medicine for treating IBS and preparation method thereof | |
| CN101411798A (en) | Chinese medicine preparation for treating schizophrenia | |
| CN108186749A (en) | Treat Chinese medicine composition of cervical spondylosis and preparation method thereof | |
| CN107596331A (en) | A kind of Chinese medicine preparation and preparation method for treating stomach cancer | |
| CN104784495A (en) | Traditional Chinese medicine preparation for treating infantile convulsion and preparation method | |
| CN100408048C (en) | Capsule for treating rheumatism and rheumatoid diseases and scapulohumeral periarthritis and preparation method thereof | |
| CN104689107A (en) | Traditional Chinese medicine for treating nearsightedness and preparation method thereof | |
| CN110179953A (en) | A kind of Chinese medicine composition of relieving mental strain and helping sleep and its application | |
| CN103877204B (en) | A kind of Chinese medicine oral liquid and preparation method for the treatment of obesity | |
| CN101468071B (en) | Chinese medicine medicine for suppressing and alleviating sex urge for male and female | |
| CN108686094A (en) | A kind of Traditional Chinese medicine for decreasing blood sugar and preparation method thereof | |
| CN102727668A (en) | Chinese medicine composition with effect of alleviating asthenopia and preparation method thereof | |
| CN102319404B (en) | Preparation method of traditional Chinese medicine lotion for treating alcoholism-type bedsore | |
| CN105746773A (en) | Health care tea for control of diabetic cognitive disorder | |
| CN105920409A (en) | Medicinal preparation for treating Alzheimer disease and application of medicinal preparation | |
| CN104940551B (en) | A kind of drink and preparation method of adjustable hemopoietic function of bone marrow | |
| CN104707031A (en) | Traditional Chinese medicine composition for treating senile osteoporosis and preparation method thereof | |
| CN114767798A (en) | Liver-protecting fat-reducing oral liquid and preparation method thereof | |
| CN104474353A (en) | Medicine for treating myasthenia gravis and preparation method of medicine | |
| CN103784791B (en) | One treats cataractous herbal liquid medicine and preparation method thereof | |
| CN109432210A (en) | A kind of anaesthetic that treating skin grasserie and its preparation process |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |