CN108478724A - It is a kind of to be used to treat Chinese medicine composition of myopia and preparation method thereof - Google Patents
It is a kind of to be used to treat Chinese medicine composition of myopia and preparation method thereof Download PDFInfo
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- 238000002360 preparation method Methods 0.000 title claims abstract description 9
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- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims abstract description 15
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- 240000002045 Guettarda speciosa Species 0.000 claims abstract description 14
- 235000001287 Guettarda speciosa Nutrition 0.000 claims abstract description 14
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- A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
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- A61K36/232—Angelica
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Abstract
It is a kind of to be used to treat Chinese medicine composition of myopia and preparation method thereof, it is related to the field of Chinese medicines, is made of the raw material of following parts by weight:10 15 parts of cassia seed, 10 15 parts of the fruit of glossy privet, 79 parts of chrysanthemum, 57 parts of the fruit of Chinese wolfberry, 57 parts of plantain seed, 57 parts of the tuber of dwarf lilyturf, 35 parts of mother-of-pearl, 10 15 parts of the membrane of a chicken's gizzard, 10 15 parts of mulberry fruit, 35 parts of the root of Dahurain angelica, 35 parts of asarum, 13 parts of radix rehmanniae preparata, 13 parts of Radix Codonopsis, 57 parts of lophatherum gracile;The popularization of the present invention is capable of providing a kind of Chinese medicine composition that can treat myopia, have effects that clearing heat and detoxicating, dispersing stagnated hepatoqi, blood circulation-activating eyesight-improving, for treating a variety of causes caused by myopia, so that patient is improved in a short time eyesight, it has no toxic side effect, therapeutic effect is notable.
Description
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of Chinese medicine composition and its preparation side for treating myopia
Method.
Background technology
Myopia, names of disease of tcm.It is eye in the case where adjusting relaxed state, parallel rays focus after the refraction of the dioptric system of eye
It falls before retina.Ancient medical book is early recognized this disease, and referred to as mesh is unable to long sight, also known as the nearly timid remote disease of energy, until《Mesh is through big
At》Begin to claim myopia.By congenital generation, myopic degree the higher person is also known as closely looked.The generation and heredity, development, environment etc. of myopia are all
It is multifactor related, but exact pathogenesis is still under study for action.There are many origin causes of formation for myopia, such as due to being drawn with eye mode is bad
The myopia risen, it is near-sighted caused by heredity, due to drug-induced myopia etc..Its incidence has in recent years rises year by year
Trend, especially juvenile onset rate become apparent, and there is no preferable medicine at present, majority using wear glasses,
Health-care appliance is treated, and uses operative treatment, the health cares such as current market sales of eye-protection instrument, physiotherapeutic glasses for myopia in severe case
Instrument cannot cure although some effects, and easily recur and aggravate the state of an illness;There are also drugs, and effect is bad, treatment
Time is long;There are great risks for operative treatment, and sequelae is more.Why related drugs on the market and therapeutic equipments be not up to
It is to have left this because treatment myopia is Huoxue Shugan at all and go blindly searching treatment close at all to the purpose effected a permanent cure
Depending on the drug or method of eye illness presentation, can all there are the adverse consequences such as the bad, the high recurrence rate even exacerbation state of an illness of effect.
Invention content
The purpose of the present invention has the tendency that rising year by year aiming at its incidence in recent years, especially juvenile onset rate
Become apparent, and there is no preferable medicine at present, it is most using wear glasses, health-care appliance is treated, in serious conditions
It is lower use operative treatment, the health care instruments such as current market sales of eye-protection instrument, physiotherapeutic glasses for myopia, although some effects, not
It can cure, and easily recur and aggravate the state of an illness;There are also drugs, and effect is bad, and treatment time is long;Operative treatment presence is very big
Risk, and the deficiency that sequelae is more, and a kind of Chinese medicine composition for treating myopia is provided, treatment of the present invention
The Chinese medicine composition of myopia has effects that dispersing stagnated hepatoqi, blood circulation-activating eyesight-improving, is fundamentally treated by dispersing liver and promoting blood circulation to reach
The purpose of myopia.
The present invention is made of the raw material of following parts by weight:10-15 parts of cassia seed, 10-15 parts of the fruit of glossy privet, 7-9 parts of chrysanthemum, Chinese holly
5-7 parts of matrimony vine, 5-7 parts of plantain seed, 5-7 parts of the tuber of dwarf lilyturf, 3-5 parts of mother-of-pearl, 10-15 parts of the membrane of a chicken's gizzard, 10-15 parts of mulberry fruit, the root of Dahurain angelica
3-5 parts, 3-5 parts of asarum, 1-3 parts of radix rehmanniae preparata, 1-3 parts of Radix Codonopsis, 5-7 parts of lophatherum gracile.
Preferably, it is made of the raw material of following parts by weight:13 parts of cassia seed, 13 parts of the fruit of glossy privet, 8 parts of chrysanthemum, the fruit of Chinese wolfberry 6
Part, 6 parts of plantain seed, 6 parts of the tuber of dwarf lilyturf, 4 parts of mother-of-pearl, 13 parts of the membrane of a chicken's gizzard, 13 parts of mulberry fruit, 4 parts of the root of Dahurain angelica, 4 parts of asarum, 2 parts of radix rehmanniae preparata,
2 parts of Radix Codonopsis, 6 parts of lophatherum gracile.
The preparation method of above-mentioned Chinese medicine preparation includes below step:
(1) by cassia seed, the fruit of glossy privet, chrysanthemum, the fruit of Chinese wolfberry, plantain seed, the tuber of dwarf lilyturf, mother-of-pearl, the membrane of a chicken's gizzard, mulberry fruit, the root of Dahurain angelica,
Asarum, radix rehmanniae preparata, Radix Codonopsis, lophatherum gracile first with 2 ° of -5 ° of cold water soaks 5 hours, are put into drying box and are dried after immersion, dry box temperature
At 46 ° -50 °, drying time is 20 minutes for degree control, spare after placement room temperature;
(2) take it is dry after cassia seed, the fruit of glossy privet, chrysanthemum, the fruit of Chinese wolfberry, plantain seed grinds, and is ground into 300-400 mesh
Micro mist, micro mist is put into fill 75% ethanol water, then it is spare to be concentrated into medicinal extract extracting solution by refluxing extraction 5 times;
(3) take it is dry after the tuber of dwarf lilyturf, mother-of-pearl, the membrane of a chicken's gizzard, mulberry fruit, the root of Dahurain angelica, asarum, radix rehmanniae preparata, Radix Codonopsis, lophatherum gracile is put into
It pounds in container, holding container temperature pounds at graininess under 30 DEG C of environment, is then placed in and decocts in container, decoction 3 times, often
It is secondary to decoct 0.5 hour, then obtained decoction liquor is filtered, filtered filtrate is taken, medicinal extract is made in filtrate boiling concentration
It is spare;
(4) medicinal extract that the 2nd step and the 3rd step obtain is uniformly mixed, is then dried, it is 300- to be crushed again after dry
Obtained micro mist is added after filler, adhesive and tablet, pill, paste is made or is packed into gelatin hard by the micro mist of 400 mesh
Capsule.In above-mentioned each traditional Chinese medicine ingredients:
Cassia seed, cassia seed, bitter but sweet flavor is cool in nature, there is clearing liver, improving eyesight, can control wind-heat cute conjunctivitis, glaucoma, night blindness etc.
It takes a disease, is monarch drug in a prescription.
The fruit of glossy privet, liver and kidney benefiting, clearind deficient heat, improving eyesight.It cures mainly:Light-headedness, soreness and weakness of waist and knees, seminal emission, poliosis, hectic fever due to yin tide
Heat, mesh is secretly unknown, the deficiency of liver-yin and kidney-yin, is monarch drug in a prescription.
Chrysanthemum, mildly bitter flavor, property gas peace have the effect of relieve heat heat-clearing, flat liver improving eyesight, are ministerial drug.
The fruit of Chinese wolfberry, sweet in flavor, property gas peace has the effect of nourshing kidney, moistening lung, tonifying liver, improving eyesight, is ministerial drug.
The effect of plantain seed, sweet in flavor, cold nature have reducing fever and causing diuresis, and excreting dampness is treating stranguria, improving eyesight, eliminating the phlegm is ministerial drug.
The tuber of dwarf lilyturf, sweet in flavor, slight bitter, cold nature have the effect of nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire, are ministerial drug.
Mother-of-pearl, taste is micro- salty, cold nature, has the effect of calming the liver, improving eyesight of calming the frightened, is adjutant.
The membrane of a chicken's gizzard, sweet in flavor, property gas peace has the effect of stomach strengthening and digestion promoting, arresting seminal emission, is adjutant.
Mulberry fruit, sweet in flavor, sour, cold nature have the effect of enriching yin of enriching blood, fluid dryness, are adjutant.
The root of Dahurain angelica, acrid flavour, it is warm-natured and, there is relieve heat dehumidifying, be adjutant the effect of sensible analgesic, detumescence and apocenosis.
Asarum, acrid flavour, it is warm-natured and, there is expelling wind and clearing away cold, be adjutant the effect of sensible analgesic, warming lung and resolving fluid.
Radix rehmanniae preparata, it is sweet in flavor, it is warm-natured and, have effects that enriching yin of enriching blood, to make medicine.
Radix Codonopsis, sweet in flavor, property gas peace has the effect of tonifying middle-Jiao and Qi, strengthening spleen and tonifying lung, to make medicine.
Lophatherum gracile, sweet in flavor, cold nature have the effect of clearing heat and relieving fidgetness, diuresis, to make medicine.
The method have the advantages that:
The present invention is capable of providing a kind of Chinese medicine composition for treating myopia, has clearing heat and detoxicating, dispersing stagnated hepatoqi, promoting blood circulation bright
Purpose effect, for treating a variety of causes caused by myopia, so that patient is improved in a short time eyesight, nontoxic pair
Effect, therapeutic effect are notable.
Specific implementation mode
The present invention is made of the raw material of following parts by weight:10-15 parts of cassia seed, 10-15 parts of the fruit of glossy privet, 7-9 parts of chrysanthemum, Chinese holly
5-7 parts of matrimony vine, 5-7 parts of plantain seed, 5-7 parts of the tuber of dwarf lilyturf, 3-5 parts of mother-of-pearl, 10-15 parts of the membrane of a chicken's gizzard, 10-15 parts of mulberry fruit, the root of Dahurain angelica
3-5 parts, 3-5 parts of asarum, 1-3 parts of radix rehmanniae preparata, 1-3 parts of Radix Codonopsis, 5-7 parts of lophatherum gracile.
Embodiment 1:
Preferably, it is made of the raw material of following parts by weight:13 parts of cassia seed, 13 parts of the fruit of glossy privet, 8 parts of chrysanthemum, the fruit of Chinese wolfberry 6
Part, 6 parts of plantain seed, 6 parts of the tuber of dwarf lilyturf, 4 parts of mother-of-pearl, 13 parts of the membrane of a chicken's gizzard, 13 parts of mulberry fruit, 4 parts of the root of Dahurain angelica, 4 parts of asarum, 2 parts of radix rehmanniae preparata,
2 parts of Radix Codonopsis, 6 parts of lophatherum gracile.
Specific preparation method following steps:
(1) by cassia seed, the fruit of glossy privet, chrysanthemum, the fruit of Chinese wolfberry, plantain seed, the tuber of dwarf lilyturf, mother-of-pearl, the membrane of a chicken's gizzard, mulberry fruit, the root of Dahurain angelica,
Asarum, radix rehmanniae preparata, Radix Codonopsis, lophatherum gracile first with 2 ° of -5 ° of cold water soaks 5 hours, are put into drying box and are dried after immersion, dry box temperature
At 46 ° -50 °, drying time is 20 minutes for degree control, spare after placement room temperature;
(2) take it is dry after cassia seed, the fruit of glossy privet, chrysanthemum, the fruit of Chinese wolfberry, plantain seed grinds, and is ground into 300-400 mesh
Micro mist, micro mist is put into fill 75% ethanol water, then it is spare to be concentrated into medicinal extract extracting solution by refluxing extraction 5 times;
(3) take it is dry after the tuber of dwarf lilyturf, mother-of-pearl, the membrane of a chicken's gizzard, mulberry fruit, the root of Dahurain angelica, asarum, radix rehmanniae preparata, Radix Codonopsis, lophatherum gracile is put into
It pounds in container, holding container temperature pounds at graininess under 30 DEG C of environment, is then placed in and decocts in container, decoction 3 times, often
It is secondary to decoct 0.5 hour, then obtained decoction liquor is filtered, filtered filtrate is taken, medicinal extract is made in filtrate boiling concentration
It is spare;
(4) medicinal extract that the 2nd step and the 3rd step obtain is uniformly mixed, is then dried, it is 300- to be crushed again after dry
Obtained micro mist is added after filler, adhesive and tablet, pill, paste is made or is packed into gelatin hard by the micro mist of 400 mesh
Capsule.Clinical observation on the therapeutic effect
1, general information
Selection of clinical Patients with 300 Cases, wherein man 150, female 150, wherein 10-15 Sui 75,15-25 Sui 75,25-
35 years old 75,35-45 Sui 75.
2, diagnostic criteria
It is effective:Eyesight quickly improves, and observes 3 months without rebound person.
It improves:Eyesight slightly improves, and can maintain and not deteriorate in existing eyesight level.
In vain:It is invalid after medication.
3, therapy
Using embodiment 1, manufactured capsule, every 1g containing crude drug are early, middle and late daily respectively to take one to patient
Grain, 15 days as one therapeutic course at least take 3 course for the treatment of.
4, treatment results
Drug made of Chinese medicine preparation of the present invention is carried out for 300 clinical samples to treat, therapeutic effect is such as
Under:
Clinical samples total number of persons:300 people
The clinical samples that 200 therapeutic effects improve be discontinued 2 years and are observed, recurrence is as follows:
Model case is as follows:
Case 1, Liu, man 15 years old, suffer from high myopia, object at the moment can not be seen, use the product 3 of embodiment 1
After a course for the treatment of, it can obviously feel that eyesight improves, after being continuing with 6 courses for the treatment of, vision restoration to 1.0 has been discontinued 2 years, has ignored
Power rebound sign, has no adverse reaction.
Case 2, it is neat certain, female 24 years old, two eye visions are 0.5, before once with laser surgery treatment mistake, but eyesight after 1 year
Rebound, eyesight are returned to 0.5, and after 3 courses for the treatment of of product of embodiment 1, vision restoration to 0.8 is continuing with 6 courses for the treatment of
Afterwards, vision restoration has been discontinued 2 years, do not rebound sign to 1.2.
Case 3, at certain, female 35 years old, binocular vision 0.4, continue myopia nearly 25 years, tried it is various treatment myopia medicines
Object, without positive effect, after 10 courses for the treatment of of product of embodiment 1, binocular vision all reaches 0.8, at present still in the treatment.
Certainly, the present invention can also have other various embodiments, without deviating from the spirit and substance of the present invention,
Those skilled in the art make various corresponding change and deformations in accordance with the present invention, but these it is corresponding change and
Deformation should all belong to the scope of protection of the present invention.
Claims (3)
1. a kind of Chinese medicine composition for treating myopia is made from the following raw materials in parts by weight:10-15 parts of cassia seed, female
Loyal sub- 10-15 parts, 7-9 parts of chrysanthemum, 5-7 parts of the fruit of Chinese wolfberry, 5-7 parts of plantain seed, 5-7 parts of the tuber of dwarf lilyturf, 3-5 parts of mother-of-pearl, the membrane of a chicken's gizzard
10-15 parts, 10-15 parts of mulberry fruit, 3-5 parts of the root of Dahurain angelica, 3-5 parts of asarum, 1-3 parts of radix rehmanniae preparata, 1-3 parts of Radix Codonopsis, 5-7 parts of lophatherum gracile.
2. a kind of Chinese medicine composition for treating myopia according to claim 1, by the raw material system of following parts by weight
At:13 parts of cassia seed, 13 parts of the fruit of glossy privet, 8 parts of chrysanthemum, 6 parts of the fruit of Chinese wolfberry, 6 parts of plantain seed, 6 parts of the tuber of dwarf lilyturf, 4 parts of mother-of-pearl, in chicken
13 parts of gold, 13 parts of mulberry fruit, 4 parts of the root of Dahurain angelica, 4 parts of asarum, 2 parts of radix rehmanniae preparata, 2 parts of Radix Codonopsis, 6 parts of lophatherum gracile.
3. a kind of preparation method as claimed in claim 1 or 2 for treating the Chinese medicine composition of myopia, it is characterised in that
Including below step:
(1) by cassia seed, the fruit of glossy privet, chrysanthemum, the fruit of Chinese wolfberry, plantain seed, the tuber of dwarf lilyturf, mother-of-pearl, the membrane of a chicken's gizzard, mulberry fruit, the root of Dahurain angelica, carefully
Pungent, radix rehmanniae preparata, Radix Codonopsis, lophatherum gracile first with 2 ° of -5 ° of cold water soaks 5 hours, is put into drying box and is dried after immersion, drying box temperature
At 46 ° -50 °, drying time is 20 minutes for control, spare after placement room temperature;
(2) take it is dry after cassia seed, the fruit of glossy privet, chrysanthemum, the fruit of Chinese wolfberry, plantain seed grinds, and it is micro- to be ground into 300-400 purposes
Powder, micro mist is put into fill 75% ethanol water, then it is spare to be concentrated into medicinal extract extracting solution by refluxing extraction 5 times;
(3) take it is dry after the tuber of dwarf lilyturf, mother-of-pearl, the membrane of a chicken's gizzard, mulberry fruit, the root of Dahurain angelica, asarum, radix rehmanniae preparata, Radix Codonopsis, lophatherum gracile is put into container
It inside pounds, holding container temperature pounds at graininess under 30 DEG C of environment, is then placed in and decocts in container, decoct 3 times, decoct every time
It boils 0.5 hour, then obtained decoction liquor is filtered, takes filtered filtrate, it is spare that medicinal extract is made in filtrate boiling concentration;
(4) medicinal extract that the 2nd step and the 3rd step obtain is uniformly mixed, is then dried, it is 300-400 to be crushed again after dry
Obtained micro mist is added after filler, adhesive and tablet, pill, paste is made or is packed into snap fit capsule by purpose micro mist.
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