CN101926890B - Medicament for treating xerophthalmia - Google Patents
Medicament for treating xerophthalmia Download PDFInfo
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- CN101926890B CN101926890B CN2010102550493A CN201010255049A CN101926890B CN 101926890 B CN101926890 B CN 101926890B CN 2010102550493 A CN2010102550493 A CN 2010102550493A CN 201010255049 A CN201010255049 A CN 201010255049A CN 101926890 B CN101926890 B CN 101926890B
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Abstract
The invention relates to a medicament for treating xerophthalmia. In the medicament, traditional Chinese medicinal herbs with simple preparation method and low cost are used as a main agent of the medicament, Chinese medicinal materials of manchurian wildginger, Chinese angelica, mulberry leaf, Chinese wolfberry and the like are mainly adopted, and a method of infusion is adopted, so the medicament is convenient to be carried and administrated by patients; and simultaneously, the medicament has the good effect on the treatment of the xerophthalmia, and is suitable for the patients who suffer from the xerophthalmia at age groups of youth, prime of life, agedness and the like.
Description
Technical field
The present invention relates to a kind of medicine, be specifically related to a kind of medicine for the treatment of xerophthalmia.
Background technology
Xerophthalmia is a kind of because the tear film that causes unusually of the amount of tear or matter is unstable or the infringement of eye table organization, thereby causes a class disease of a malaise symptoms, is the common disease of ophthalmology, common symptom comprises that eyes are dried dry and astringent puckery, tired easily, sleepy, can itch, foreign body sensation is arranged, the pain burning sensation, eyelid is tight heavy, the secretions thickness, aversion to wind, photophobia, stimulate to external world very sensitive, temporary blurred vision; Sometimes eyes are too dried, and basic oligodacrya stimulates the reflexive lacrimal secretion on the contrary and causes the symptom that usually drops tears; Can be red and swollen than the severe patient eyes, hyperemia, keratinization, the broken skin of corneal epithelium and have filament to adhere to, long-term injury then can cause the angle conjunctive disorder, thereby and can affect one's power of vision people's work and study are caused great influence.
That the treatment xerophthalmia is used at present is the artificial tears the most widely, mainly be by apish tear composition, drip the effect that the alleviating dry eye symptom is arranged in the eye table, but it is shorter to hold time, and most artificial tears contains antiseptic and additive, and life-time service is shown prejudicial effect to eye; In addition lacrimal point or lacrimal ductule being stopped up the quality and quantity that can stop the discharge of tear and improve tear, is the most frequently used non-drug therapy of treatment xerophthalmia.In addition, the operation method of employing sublingual gland free grafting is treated the severe forms of dry eye disease becomes research emphasis, but indication is answered careful selection, the scope of using is less, and the cost of treatment is higher, can't be promoted widely, and application motherland traditional medicine is for the treatment of xerophthalmia, also be in the comparatively primary stage, major part can only realize by the mode of acupuncture or herbal fumigation, and the research of fundamentally xerophthalmia being treated is also few, and therefore being badly in need of a kind of medicine that can fundamentally treat xerophthalmia fills up this blank.
Summary of the invention
For solving the various difficult problems of above-mentioned treatment xerophthalmia, easy to utilize, we select Chinese medicine Folium Mori drink treatment xerophthalmia, and are simple and easy to do, with the economic pressures of reduction of patient greatly.The invention provides a kind of medicine of new treatment xerophthalmia, the prescription of this medicine mainly comprises Chinese herbal medicine such as Radix Angelicae Sinensis, Herba Asari, Fructus Lycii, Folium Mori, after adopting these a few flavor Chinese medicines, xerophthalmia can fundamentally treated, conditioning patient self internal organs have mainly been adopted, improve the situation of the sufferer hepatic and renal YIN deficiency by conditioning, thereby in the symptom of fundamentally having improved xerophthalmia, overcome the drawback that existing Therapeutic Method and medicine are cured the symptoms, not the disease, for the treatment of xerophthalmia provides a brand-new thinking and method.
Main technical schemes of the present invention is: the each component of this medicine is according to the weight portion meter, and its proportioning is: Radix Angelicae Sinensis 1-20 part, Herba Asari 1-10 part, Fructus Lycii 1-30 part, Folium Mori 1-30 part.
Treatment mechanism of the present invention is: by theory of Chinese medical science, the hepatic and renal YIN deficiency, order void must not flourish foster and dry and astringent, few liquid, wind syndrome caused by deficiency is disturbed order and consumed Tianjin and decrease liquid in addition, and the deficiency of body fluid of order is promptly suffered from the xerophthalmia of modern medicine so cause dryness and uneasy feeling of the eye's sand gritty.Based on this treatment mechanism, the inventor has used 4 above-mentioned flavor Chinese medicines, Folium Mori in each Chinese medicine of distinguishing the flavor of, and dispelling wind and heat pathogens, liver heat removing and eyesight improving, suppressing the hyperactive liver and subsiding YANG are monarch; Fructus Lycii, nourishing the liver and kidney, replenishing vital essence to improve eyesight are minister; Radix Angelicae Sinensis, tonifying blood and regulating menstruation are invigorated blood circulation and are assistant; Herba Asari, the cold expelling that induces sweat, expelling pathogenic wind and restoring the functions of orifices in face is for making; All medicines share to reach nourishing the liver and kidney, the effect that tonifying YIN dispels the wind, wherein with Folium Mori as monarch drug, in medicine for the treatment of xerophthalmia before and method, all do not occur, just it is used as one of stifling medicine of external before, the inventor is through studying discovery for a long period of time, Folium Mori have effect preferably through the symptom for alleviating dry eye disease after stifling, can't fundamentally treat xerophthalmia but this external is stifling, therefore the inventor is stifling with the external Folium Mori, changes form for oral administration into, because it has above-mentioned drug effect, can fundamentally change the situation of the sufferer hepatic and renal YIN deficiency, thereby unusual in amount that fundamentally solves tear or matter, the treatment xerophthalmia, other a few flavor ministerial drugs can with the good compatibility of monarch drug, and all can improve the symptom of the hepatic and renal YIN deficiency, thereby make medicine reach best drug effect.
In order to play better effect, and make things convenient for patient's use, the not first-selected method of controlling of frying in shallow oil that adopts Chinese medicine of the present invention, but adopted the mode of convenient tea-drinking, with Radix Angelicae Sinensis, Herba Asari, Fructus Lycii, above-mentioned Chinese crude drug such as Folium Mori is made medicated bag, the method that employing is taken after being infused in hot water or decoction is for tea-drinking usefulness, can effectively treat the hepatic and renal YIN deficiency or be subjected to the medicine of the xerophthalmia that wind syndrome caused by deficiency causes, and is easy to use, cheap and be free from side effects, avoided only adopting a defective of curing the symptoms, not the disease stifling and that western medicine therapy is brought.
Through the studying for a long period of time and manufacturing experimently of inventor, when the proportioning of finally having found above-mentioned Chinese medicine was following value, the effect of treatment was best, and the weight portion of this proportioning is: Radix Angelicae Sinensis 10-20 part, Herba Asari 1-5 part, Fructus Lycii 5-10 part, Folium Mori 10-30 part.Adopt this proportioning, improved the consumption of Folium Mori emphatically, can better play drug effect, and when adopting this compatibility, after soaking through tea-drinking, can be with the better stripping of effective ingredient wherein, and after other Chinese medicines of respectively distinguishing the flavor of are adjusted into above-mentioned consumption, played the effect of vital base and primordial QI consolidating, in the time of the treatment disease, also having preferably, health-care effect can play the effect that improves immunity.
With above-mentioned medication preparation is tea-drinking, and its preparation method is as follows:
With above each component material medicine mix homogeneously, to insert and be ground into coarser powder in the Chinese medicine grinder jointly, coarser powder can be crossed the 100-120 mesh sieve and get final product, and with the filter paper bag of packing into of the thick medicamental pulverata after pulverizing, per 10 grams mix medicamental pulverata and are one bag and are packaged as finished product.Pulverize that medicine is careful to be helped bubbling out of effective ingredient and take.
Instructions of taking: adopt and take with boiled water, take 1 bag at every turn, take every day 2 times.Taking 15 days is a course of treatment.Generally taking can have remarkable result 2 courses of treatment.
Except above-mentioned medication preparation is become the tea-drinking, for the patient who is fit to all ages and classes stage uses, its preparation can also be become following dosage form: cream, pellet, ball, loose, dosage forms such as capsule, oral liquid, but above-mentioned dosage form is oral preparations, and the preparation method that is adopted can adopt existing method directly to prepare according to above-mentioned proportioning.
The medicine of treatment xerophthalmia provided by the present invention, because the Chinese medicine that is China that adopts, cheap can promoting the use of on a large scale, simultaneously owing to adopted the method that brews, can replace tea-drinking, more help taking of patient, the patient who is fit to various age brackets such as youth, the prime of life, old age takes; Treatment time is short, and instant effect after process clinical experiment Most patients is taken 3-6 the course of treatment, can obtain curing, and cure rate is more than 90%; Owing to all adopt the Chinese crude drug of pure natural, there is not the addiction of Western medicine, also just reduced side effects of pharmaceutical drugs; Adopt the packing of filter bag, both made things convenient for daily drinking, be convenient for carrying medication at any time again,, can also adopt other dosage forms simultaneously, enriched its application in all cases more to alleviate and to remove the misery of patient's xerophthalmia.
The specific embodiment
Embodiment 1
A kind of medicine for the treatment of xerophthalmia, each component are according to the weight portion meter, and its proportioning is: 10 parts of Radix Angelicae Sinensis, and 2 parts of Herba Asaris, 20 parts of Fructus Lyciis, 10 parts on Folium Mori, every part of weight is 20g.
Add man-hour with above each component material medicine by the proportioning mix homogeneously, insert and be ground into coarser powder in the Chinese medicine grinder jointly, coarser powder can be crossed 100 mesh sieves and get final product, with the filter paper bag of packing into of the thick medicamental pulverata after pulverizing, per 10 grams mix medicamental pulverata and are one bag and are packaged as finished product.Take 1 bag at every turn, take every day 2 times.
Embodiment 2
A kind of medicine for the treatment of xerophthalmia, each component are according to the weight portion meter, and its proportioning is: 20 parts of Radix Angelicae Sinensis, and 5 parts of Herba Asaris, 10 parts of Fructus Lyciis, 15 parts on Folium Mori, every part of weight is 5g.
Add man-hour with above each component material medicine by the proportioning mix homogeneously, insert and be ground into coarser powder in the Chinese medicine grinder jointly, coarser powder can be crossed 100 mesh sieves and get final product, and the thick medicamental pulverata after pulverizing is carried out the refined honey pill, every ball 10 grams, the every box of 10 balls packages spare.Take 1 ball at every turn, take every day 2 times.
Embodiment 3
A kind of medicine for the treatment of xerophthalmia, each component are according to the weight portion meter, and its proportioning is: 5 parts of Radix Angelicae Sinensis, and 5 parts of Herba Asaris, 10 parts of Fructus Lyciis, 10 parts on Folium Mori, every part of weight is 10g.
Add man-hour with above each component material medicine by the proportioning mix homogeneously, insert and be ground into coarser powder in the Chinese medicine grinder jointly, coarser powder can be crossed 100 mesh sieves and get final product, and the thick medicamental pulverata after pulverizing is incapsulated, per 5 grams are one bag and are packaged as finished product.One bag of each clothes are taken twice every day.
Embodiment 4
A kind of medicine for the treatment of xerophthalmia, each component are according to the weight portion meter, and its proportioning is: 20 parts of Radix Angelicae Sinensis, and 10 parts of Herba Asaris, 20 parts of Fructus Lyciis, 30 parts on Folium Mori, every part of weight is 30g.
Add man-hour with above each component material medicine by the proportioning mix homogeneously, decocting and concentrating is made oral liquid.Every 10ml/ props up, and takes two every day.
Embodiment 5
A kind of medicine for the treatment of xerophthalmia, each component are according to the weight portion meter, and its proportioning is: 1 part of Radix Angelicae Sinensis, and 2 parts of Herba Asaris, 15 parts of Fructus Lyciis, 25 parts on Folium Mori, every part of weight is 14g.
Add man-hour with above each component material medicine by the proportioning mix homogeneously, insert and be ground into coarser powder in the Chinese medicine grinder jointly, coarser powder can be crossed 120 mesh sieves and get final product, with the filter paper bag of packing into of the thick medicamental pulverata after pulverizing, per 10 grams mix medicamental pulverata and are one bag and are packaged as finished product.Take 1 bag at every turn, take every day 2 times.
Experimental example 1
Patient Zhang, man, 45 years old, dry and astringent uncomfortable 2 years of eye, diagnose xerophthalmia behind the ophthalmologic examination, lacrimal secretion test check tear 5mm/5min provides through the inventor, take the medicine of the treatment xerophthalmia that makes according to the embodiment of the invention 1 described proportioning and method, and according to every day each 1 time sooner or later, one time one bag dosage is taken, take 40 days continuously after, look into lacrimal secretion test check tear 12mm/5min, all inadaptations are eliminated and are fully recovered.So far not recurrence, the patient reacts well, has no side effect.
Experimental example 2
Patient Wang, the woman, 57 years old, diagnosis xerophthalmia 3 years was dripped tear always and is so kept symptom.Look into lacrimal secretion test check tear 4mm/5min (two); Advise through the inventor, take the medicine of the treatment xerophthalmia that makes according to the embodiment of the invention 1 described proportioning and method, and according to every day each 1 time sooner or later, one time one bag dosage is taken, after taking 3 months continuously, look into lacrimal secretion test check tear 15mm/5min (two), all inadaptations are eliminated and are fully recovered.
Experimental example 3
Patient Chen, the man, 22 years old, the life-time service computer was diagnosed as xerophthalmia 1 year, looked into lacrimal secretion test check tear 6mm/5min (two); Advise through the inventor, take the oral agents of the treatment xerophthalmia that makes according to the embodiment of the invention 4 described proportionings and method, and according to every day each 1 time sooner or later, one time one dosage is taken, take continuously 1 month surplus, look into lacrimal secretion test check tear 15mm/5min (two), all inadaptations are eliminated and are fully recovered.
Experimental example 4
The patient becomes certain, the man, and 76 years old, diagnosis xerophthalmia 7 years was looked into lacrimal secretion test check tear 2mm/5min (right side), 1mm/5min (left side); Advise through the inventor, take the medicine of the treatment xerophthalmia that makes according to the embodiment of the invention 1 described proportioning and method, and according to every day each 1 time sooner or later, one time one bag dosage is taken, take 5 months continuously after, look into lacrimal secretion test check tear 11mm/5min (right side), 7mm/5min (left side), all inadaptations are clearly better, and immunity of organisms increases, and body constitution improves significantly before taking medicine.
Claims (3)
1. medicine for the treatment of xerophthalmia, it is characterized in that: the each component of this medicine is according to the weight portion meter, and its proportioning is: Radix Angelicae Sinensis 10-20 part, Herba Asari 1-5 part, Fructus Lycii 5-10 part, Folium Mori 10-30 part.
2. the method for the medicine of xerophthalmia is treated in preparation according to claim 1, it is characterized in that: concrete steps are: with each component material medicine mix homogeneously proportionally, insert and be ground into coarser powder in the pulverizer jointly, with the filter paper bag of packing into of the drug powder after pulverizing, it is one bag that per 10 grams mix medicamental pulverata, is packaged as finished product.
3. method according to claim 2 is characterized in that: the coarser powder after the pulverizing is crossed the 100-120 mesh sieve.
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CN2010102550493A CN101926890B (en) | 2010-08-17 | 2010-08-17 | Medicament for treating xerophthalmia |
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CN2010102550493A CN101926890B (en) | 2010-08-17 | 2010-08-17 | Medicament for treating xerophthalmia |
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CN101926890B true CN101926890B (en) | 2011-11-30 |
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CN102920911B (en) * | 2012-12-05 | 2014-05-07 | 青岛市中心医院 | Traditional Chinese medicine for treating keratoconjunctivitis sicca and preparation method thereof |
CN104435516A (en) * | 2014-11-27 | 2015-03-25 | 邹士东 | Traditional Chinese medicine combination for treating liver-kidney yin deficiency type xerophthalmia |
CN104435685A (en) * | 2014-11-30 | 2015-03-25 | 顾蔷怡 | Medicine for treating xerophthalmia and preparation method thereof |
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CN1256111C (en) * | 2003-12-29 | 2006-05-17 | 吕莎 | Drink for treating xerophthalmia and alacrimia |
CN1868332A (en) * | 2006-06-06 | 2006-11-29 | 杨伯涛 | Health-care food with function of anti vision fatigue syndrome |
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Inventor after: Zhang Hongxing Inventor after: Zhang Yanru Inventor after: Cai Nan Inventor before: Zhang Hongxing Inventor before: Cai Nan |
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Free format text: CORRECT: INVENTOR; FROM: ZHANG HONGXING CAI NAN TO: ZHANG HONGXING ZHANG YANRU CAI NAN |