CN105943753A - Traditional Chinese medicinal composition for preventing and treating chronic fatigue syndrome - Google Patents
Traditional Chinese medicinal composition for preventing and treating chronic fatigue syndrome Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
Abstract
The invention relates to a traditional Chinese medicinal composition for preventing and treating the chronic fatigue syndrome. The traditional Chinese medicinal composition is prepared from the following medicinal materials in parts by weight: 10-30 parts of radix bupleuri, 10-30 parts of radix paeoniae alba, 10-30 parts of honey-fried licorice root, 10-30 parts of immature bitter orange, 5-30 parts of cassia twig, and 5-20 parts of rhizoma acori graminei. The traditional Chinese medicinal composition can be prepared into decoctions, pills, capsules and granules according to a conventional method. The medicinal materials are carefully selected and reasonably mixed, so that the efficacies are complementary, and the synergistic interaction effect is good. The clinical application and experimental study show that when used for treating stagnation of qi which causes the chronic fatigue syndrome, the traditional Chinese medicinal composition can treat both symptoms and root causes, after healing of the chronic fatigue syndrome, the curative effects are consolidated, and the total effective rate can achieve 88.5%. The traditional Chinese medicinal composition is a pure traditional Chinese medicine product, is safe, and takes effect rapidly, the treatment cost is low, the paint of the patient is small, the drug resistance is not caused, the toxic and side effects are small, and thus the traditional Chinese medicinal composition can be easily accepted by the patient.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine composition preventing and treating chronic fatigue syndrome
Thing.
Background technology
Chronic fatigue syndrome (Chronic Fatigue Syndrome, CFS), with chronic lasting or recurrent exerbation
Mental and physical fatigue is the syndrome of principal character.Primary disease has become affects the healthy main sick kind of our people
One.From the perspective of clinical onset, main and long-term lasting excessive chronic of the morbidity of chronic fatigue syndrome
Stress be relevant.Chronic fatigue syndrome is primarily present central nervous system, immune system, hormonal system and cell line grain
The exception of body function.In terms of immunology, the function inhibitio showing as natural killer cell is exempted from quantity minimizing, low-level circulation
Epidemic disease complex, low-level autoantibody particularly antinuclear antibody and anti-thyroid antibody, immunoglobulin level change etc..Grind
Studying carefully and show that chronic fatigue syndrome mitochondrial DNA exists damage, cytokine profiles and oxidative stress take part in DNA damage mistake
Journey, so that energy synthesizes not enough and produces clinical symptoms.
The investigation of 1999 shows, the prevalence of the CFS meeting U.S. CDC standard has reached 0.42%.U.S. CDC is predicted,
CFS will become one of 21 century subject matter affecting human health.One research of the U.S. shows, estimation of personal and society are often
With individual CFS patient, cost directly or indirectly is 9436 dollars.Up till now, China there is no the big rule being specifically designed for CFS specification
Mould is investigated, but some data reflect CFS to a certain extent and have in crowd in higher distribution, especially brain worker
CFS is the most universal.China is in the people of sub-health state and alreadys more than 700,000,000, accounts for the 60%～70% of country's total population, wherein CFS
Quantity can not be underestimated.Modern medicine is currently without the Therapeutic Method of specially good effect, and main use 5-HT mediator reuptake inhibitor is such as
Paroxetine hydrochloride is treated, but curative effect can not be affirmed.So, study effective Therapeutic Method and medicine has important reality meaning
Justice.
The Chinese medicine research to primary disease, the basic principle controlled based on determining the pathogenesis of ZANG-FU disease based on the differentiation of symptoms and signs opinion, it is now recognized that function is not normal
Cause morbidity.Existing research mainly has two aspects: one is that function deficiency causes the deficiency of QI and blood essence etc. to produce
Deficiency syndrome, opinion reinforcement；Two is that the function that disorder of movement of QI causes is not normal, advocates to use regulating functional activities of vital QI method.Treatment prescription includes
BUZHONG YIQI TANG, RENSHEN YANGRONG TANG, Herba Sidae Rhombifoliae soup, " Shengyang Yiwei Decoction ", bupleurum powder for relieving liver-qi, XIAOYAO POWDER etc..
Summary of the invention
The technical problem to be solved in the present invention: the Chinese medicine of the most inexpensive a kind of preventing and treating chronic fatigue syndrome is provided
Compositions.
Technical scheme:
A kind of Chinese medicine composition preventing and treating chronic fatigue syndrome, this Chinese medicine composition is made up of the crude drug of following weight portion,
Radix Bupleuri 10-30 part, Radix Paeoniae Alba 10-30 part, Radix Glycyrrhizae Preparata 10-30 part, Fructus Aurantii Immaturus 10-30 part, Ramulus Cinnamomi 5-30 part, Rhizoma Acori Graminei 5-20 part.
The crude drug of described Chinese medicine composition is preferably: Radix Bupleuri 10-25 part, Radix Paeoniae Alba 10-25 part, Radix Glycyrrhizae Preparata 10-25 part, trifoliate orange
Real 10-25 part, Ramulus Cinnamomi 5-25 part, Rhizoma Acori Graminei 5-15 part.
The crude drug of described Chinese medicine composition is preferably: Radix Bupleuri 10-20 part, Radix Paeoniae Alba 10-20 part, Radix Glycyrrhizae Preparata 8-20 part, trifoliate orange
Real 12-20 part, Ramulus Cinnamomi 9-20 part, Rhizoma Acori Graminei 6-12 part.
Described Chinese medicine composition be make according to a conventional method decoction, watered pill, capsule, granule.
Preparation method and instructions of taking:
Making decoction: take crude drug, add water with the weight ratio of 1:8-10, decoct, potion on the one, the morning, noon and afternoon divide 3 times and take, 30 days
Being a course for the treatment of, general 1-2 takes effect the course for the treatment of, and 4-6 the course for the treatment of cures.
Make watered pill or capsule, every watered pill or capsule containing effective ingredient 3 grams, three times a day, each 2-4 grain；Make
During granule, every bag of granule is containing active ingredient 3 grams, three times a day, each 2-4 bag.Within 30 days, being a course for the treatment of, general 1-2 is shown in the course for the treatment of
Effect, cures 4-6 the course for the treatment of.
The pharmacology analysis of the present invention:
The present invention is based on motherland's Traditional Chinese Medicine theory, and inventor associate professor Xie Zhongli is from the beginning of nineteen nineties
Being engaged in study and the research of Chinese medicine, the treatment to chronic fatigue syndrome defines the theory of Chinese medical science of uniqueness and puts into practice method.
Through the clinical observation in nearly more than ten years, defining with " regulating functional activities of vital QI, activating YANG to wake up the patient from unconciousness " is the only of main treatment chronic fatigue syndrome
Bit scheme.In the disease of clinical treatment chronic fatigue syndrome, find that the cause of disease of most patient belongs to the mechanism of qi in Chinese medicine
Caused by stasis, due to depression and stagnation of QI, qi-blood-body fluid is strongly fragrant and does not reaches, and function is difficult to normally play its effect, then occur chronic
Fatigue syndrome.Through Exploration and conclusion, in conjunction with the viewpoint of classical Chinese medicine theory all diseases resulting from disorder of QI, found out " regulating functional activities of vital QI,
Activate yang invigorate blood circulation, causing resuscitation with aromatic drugs " medicine.This medicine Radix Bupleuri regulating functional activities of vital QI, joins Fructus Aurantii Immaturus, Ramulus Cinnamomi, Rhizoma Acori Graminei relieving the inhibited functional activities of QI
The same use of product, interior dredge the stagnation of QI, can thoroughly reach outward Yu Yang.Fructus Aurantii Immaturus relieving stagnant and resolving masses, can gas in promoting the circulation of blood, Radix Paeoniae and blood promotes blood circulation, osmanthus
Branch enter the heart-nutriment, can temperature three-way meridian, pass unimpeded vim and vigour, and Rhizoma Acori Graminei is had one's ideas straightened out and rouse oneself yang-energy.In side, Ramulus Cinnamomi joined by Radix Bupleuri, and one enters few sun
Arteries and veins, one enters the warp of the sun, and two medicines share, and can rouse oneself the gas defending sun very little.On the other hand, the Radix Paeoniae Alba joined by Radix Bupleuri, and one dissipates and holds back, phase
Rely on mutually, mutually promote, mutually its short and Zhan Qichang of system.Therefore hold back with the acid of the Radix Paeoniae Alba, the pungent of Radix Bupleuri processed dissipates, and pungent with Radix Bupleuri dissipates, again
The acid of assistant Radix Paeoniae is held back, and goes directly Liver Channel with priming, and plays soothing the liver reconciliation, the merit of yang invigorating yin fluid astringing resolving depression.All medicines match, and effect is complementary,
Make the same use of the moon blood of the stagnation of QI and the soft conscience dredging conscience, make to dredge and but, hold back and do not receive, for the Yi great Te of we's regulating functional activities of vital QI
Point.Entirely can reach regulating functional activities of vital QI, dissipating depression of QI opens and closes, and thoroughly reaches the effect that Yu Yang, promoting QI to circulate and dispersing the agglomeration of the pathogens, and blood are promoted blood circulation, and disease is spontaneous recovery.
The pharmacological action of each crude drug:
Radix Bupleuri: bitter in the mouth, pungent, cold nature, return liver, gallbladder meridian, main liter；The thin gas lift of this taste is main liter for sun, can draw clear sun rise and
The most strongly fragrant, fragrance catharsis again, it is apt to regulating functional activities of vital QI and thoroughly reaches yang-energy, for principal agent in side.This product is soothing the liver dissipating depression of QI in side, rises and lifts yang-energy,
Light clear pungent dissipating, can draw the gas of clear sun from upper left liter, with thin tune yang-energy, reason liver spleen, for stagnation of QI due to depression of the liver, fullness and distention in the chest and hypochondrium, under the deficiency of vital energy
Fall into etc. disease.We are mainly used in chronic fatigue syndrome with depression and stagnation of QI for main pathogenesis person.
Fructus Aurantii Immaturus: bitter in the mouth, pungent, cold nature, to return spleen, stomach, large intestine channel, have dispelling the stagnated QI removing food stagnancy, reduce phlegm except the merit of painful abdominal mass, in side, Fructus Aurantii Immaturus is bitter
Fall row, promoting QI to circulate and dispersing the agglomeration of the pathogens and declare ventilation stagnant, fry black enter blood system, and the gas in promoting the circulation of blood.Stop in stagnant, feeling of fullness distending pain, expectorant
Stagnant vapour lock, the diseases such as breast gastral cavity painful abdominal mass is vexed.Fang Zhongyu Radix Bupleuri coordinates, and lifts and use, with regulating functional activities of qi；Match with the Radix Paeoniae Alba, cure mainly QI and blood
Stasis becomes real, and the resistance of mechanism of qi numbness is obstructed, wherein Fructus Aurantii Immaturus relieving stagnant and resolving masses, fry black can gas in promoting the circulation of blood, Radix Paeoniae regulating blood flow to alleviate pains, two medicines close and
With it, QI and blood can be made to declare logical and unhappy tired all cards certainly to remove.
The Radix Paeoniae Alba: sweet in the mouth, hardship, acid, cold nature, returns liver, spleen channel.Can be nourished blood yin fluid astringing, easing the affected liver to relieve pain, and this product is sweet mends acid receipts, mends
Liver blood, holds back liver-yin and has the merit of easing the affected liver emergency of enriching blood.The cold convergence of acid, can hold back body fluid and protect cloudy blood, receive yang-energy and rush down pathogenic heat, nourish blood
With easing the affected liver, emergency and pain relieving, the pathogenic heat of eliminating pathogen in the liver, with tonifying spleen-yin；The yin fluid astringing therefore the Radix Paeoniae Alba is nourished blood, easing the affected liver and blood.This product is all for blood deficiency
Card, spontaneous sweating, the disease such as contracture pain.Fang Zhongyu Radix Glycyrrhizae matches, and acid is sweet to match with Fructus Aurantii Immaturus to change the moon, regulate the flow of vital energy and nourish blood, with
Ramulus Cinnamomi matches, and has the merit of the yin fluid astringing that nourishes blood among tune is defended, and has the effect activated yang among He Ying.
Radix Glycyrrhizae: sweet in the mouth, flat, GUIXIN, lung, spleen, stomach warp；This product has QI invigorating invigorating middle warmer, nourishing the lung to arrest cough, heat-clearing and toxic substances removing, emergency
Pain relieving, the merit of coordinating the actions of various ingredients in a prescription.Wherein Radix Glycyrrhizae Preparata invigorating the spleen and replenishing QI is on this, Radix Glycyrrhizae heat-clearing and toxic substances removing, and expelling phlegm for arresting cough effect is good.For taste
Weakness, fatigue and weakness, shortness of breath and palpitation, cough, gastral cavity abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus is, and can the toxicity of cushion and strong
Property.
Ramulus Cinnamomi: acrid in the mouth, sweet, warm in nature, return lung, the heart, bladder warp, can expelling pathognic wind from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, invigorating middle warmer benefit
Gas.The sweet temperature of this product, can activate yang to hold up and defend, enter heart channel and walk blood system, can help heart-yang, promoting blood circulation, and cold expelling row is stagnant, for flaccidity of the heart-yang, blood
Arteries and veins is obstructed, and see that cardiopalmus is dynamic, irregularly intermittent and regularly intermittent pulse, spiritlessness and weakness person.In side, Ramulus Cinnamomi effect has be join the Radix Paeoniae Alba at two: one, and the Radix Paeoniae Alba is nourished blood yin fluid astringing
And the most stagnant heresy, Ramulus Cinnamomi and battalion's warming YANG and non-impairment of YIN.Two medicines are harmonious, and one dissipates receipts, and one trembles with fear a temperature, and monoyin and monoyang mutually restricts, and
Receive and adjust Ying Wei and QI and blood, the merit of inspiration yang-energy；Ramulus Cinnamomi red complexion again, enters blood system, can promoting blood circulation；The Radix Paeoniae Alba is apt to walk cloudy point, can tonifying YIN
In protecting, relieving spasm to stop pain；Ramulus Cinnamomi can rouse oneself again spleen sun, the Radix Paeoniae Alba kind benefit nourishing stomach-YIN again, and the two is harmonious, and monoyin and monoyang amounts to warming the meridian and leads to
Network, the blood vessels that pass unimpeded, rouses oneself the function of middle-jiao yang, function of the spleen and stomach, function of spleen and stomach regulating；Two is to join Radix Glycyrrhizae, and with pungent and sweet drugs can invigorate YANG, Radix Glycyrrhizae sweet in the mouth is put down, and master returns
The heart, lung, taste warp, side processs by temperature invigorating middle warmer, replenishing QI to invigorate the spleen, therefore the deficiency of QI and blood can be controlled.This product GUIXIN warp again, can the tonification heart
Gas, agitates blood vessels, therefore has the effect of supplementing qi and invigorating vasculum.
Rhizoma Acori Graminei: acrid in the mouth, hardship, warm in nature, GUIXIN, stomach warp.There is inducing resuscitation and resolving phlegm, refreshment brain-strengthening, the merit of removing dampness to restore normal function of the stomach.This product
The pungent dry temperature of scattered hardship is led to, and fragrance is walked to alter, and not only has the merit of refreshment of having one's ideas straightened out, and has removing dampness, eliminating phlegm, wards off dirty, the effect of mind tranquilizing and the heart calming, happily
Key, to go turbid liquid, refreshment will be its chief.This product has again refreshment brain-strengthening, the merit of audition improvement Fructus Alpiniae Oxyphyllae, can control deficiency of heart-QI, palpitate with fear, loses
Sleep, forgetful etc. is demonstrate,proved.Dissipating it addition, this product fragrance is dry, enter stomach warp, can rouse oneself taste yang-energy and rise, have removing dampness by means of aromatics, stomach function regulating is taken food
Merit, therefore can be used for rousing oneself taste and taste source.Therefore this product is arduous and warm, fragrance and dissipate, happy key, sharp nine orifices, bright knowledge,
Sound, dries except wind, and by expectorant removing food stagnancy, whet the appetite alleviating distention in middle-JIAO.It addition, the comfortable gas of Rhizoma Acori Graminei, the smooth mind, happy mood, benefit will.Removing summer-heat medicine
With it, rely and eliminate the phlegm dirty turbid and defend city wall；Nourish medicinal it, the being proficient in the law of natural movement so as to a surname's knot of thought.
The most all medicines coordinate, and have regulating functional activities of vital QI, and dissipating depression of QI opens and closes, and thoroughly reaches the effect that Yu Yang, promoting QI to circulate and dispersing the agglomeration of the pathogens, and blood are promoted blood circulation.
The positive beneficial effect of the present invention:
(1) present invention is according to traditional Chinese medical science traditional theory, in conjunction with the long-term clinical practice of inventor, defines so that " regulating functional activities of vital QI activates yang
Invigorate blood circulation, causing resuscitation with aromatic drugs " it is main unique treatment regimen.This medicine selected raw material, compatibility is reasonable, and effect is complementary, can produce preferably
Synergistic function.Clinical practice and experimentation show, this medicine belongs to depression and stagnation of QI to chronic fatigue syndrome person, can specimen hold concurrently
Controlling, efficacy consolidation after healing, total effective rate is up to 88.5%.
(2) present invention is pure tcm product, safety, and medical expense is low, instant effect, and general 1-2 the course for the treatment of takes effect, patient's pain
Bitter little, not drug resistance, toxic and side effects is little, is easily accepted by patients, it is to avoid the toxic and side effects of heavy dose of use Western medicine.
(3) Chinese medicine composition of the present invention reacts good in patients, firmly gets patient's favorable comment.
Pharmacological research:
We have carried out substantial amounts of experimentation in early stage, and result of study shows, we are to the confirmed fatigue caused by chronic stress
Model nervus centralis monoaminergic nerve system has regulation effect, it is possible to decrease in Chronic Stress Model Hypothalamus in Rats, NE's contains
Amount, raises the content of 5-HIAA and 5-HT；Raise Chronic Stress Model rat hippocampus district five hydroxytryptamine 2A receptor and mRNA thereof
Express and the expression of chronic stress rat frontal lobe 5-HT2AR and mRNA；We can grow tall chronic fatigue syndrome mould
Type Mice Body quality and motor capacity, reduce the content of IL-2 in peripheral blood, have regulation effect to body's immunity.We
Protected to the chronic fatigue syndrome mouse model frontal lobe caused by chronic stress and the mitochondrial damage of neurons of hippocampus CA 1
Effect, can improve frontal lobe and neurons of hippocampus CA 1 energy metabolism.Above result of study shows, we have the most anti-slow
Property stress be caused chronic fatigue syndrome effect, its mechanism is by regulation nervus centralis monoaminergic nerve mediator and relevant to be subject to
System system, change laboratory animal weight, regulation immunologic function and protection central nervous system neurons structure of mitochondria and merit
Can, improve what energy metabolism realized.
Case is added up:
Inventor accepts chronic fatigue syndrome 138 example on the books, male 76 examples, female 62 example, man: female altogether for medical treatment from 2000-2016
Ratio is 1.23:1, patient age 22-54 year between, 36.7 years old mean age, course of disease 6-18 month, average course of disease 14
Month.
In 138 example patients, cure 89 examples altogether, account for 64.5%；Progressive 33 examples, account for 24%；Invalid 16 examples, account for 11.5%；
Total effective rate is 88.5%.
The criterion of therapeutical effect of above-mentioned case is according to the Center for Disease Control (CDC) chronic fatigue syndrome in 1994
(CFS) diagnostic criteria designs and formulates, and standard is as follows:
(1) curing: fatigue recovery is normal, attention is concentrated, and forgetful is obviously improved, and depressive emotion disappears, and sleep is normal, myalgia
Disappearing, arthralgia disappears, and heating disappears, and throat pain disappears, and cervical region or axillary gland pain disappear, and muscle weakness disappears, prominent
The taediumvitae continuing more than 24 hours after the fatigue so occurred and slight work disappears, and continues February more than, maintains above nothing in June
Recurrence；
(2) progressive: tired basic to recover normal, attention is relatively concentrated, forgetful improvement, and depressive emotion alleviates, time have insomnia, muscle
Alleviation of pain is light, and arthralgia alleviates, and heating alleviates, and throat pain alleviates, and cervical region or axillary gland pain relief, muscle weakness alleviates
Losing, the taediumvitae continuing more than 24 hours after the fatigue occurred suddenly and slight work alleviates, and continues January more than, maintenance March with
On；
(3) invalid: above-mentioned various symptoms are not improved or deterioration person.
Model case:
Case 1, Lee, female, 38 years old, people from Zhengzhou City Henan Province.There is fatigue without obvious inducement in March, 2007, and companion's attention is not
Concentrate, forgetful, unhappy, insomnia, time have arthralgia.Identify oneself operating pressure not draw attention greatly and.Rear above-mentioned symptom is held
Renew, do not alleviate after rest.Then going to a doctor in Henan Prov. People's Hospital, pharyngeal have mild hyperaemia, and remaining every inspection is without bright
Aobvious abnormal.Hospital, with " tired to be checked " diagnosis and treatment, gives oral vitamin C, and about half a year treated by compound vitamin B, and fatigue has no bright
Aobvious alleviate, be then diagnosed as " chronic fatigue syndrome ", and oral paroxetine hydrochloride and having not yet to see after Chinese medicine SHENGMAI YIN treatment March
It is clearly better, seeks medical advice in inventor in February, 2009.Examining and see: complexion is partially dark, tired, forgetful, depressed, insomnia is strong
Forget, pharyngeal mild hyperaemia, time have arthralgia, easily angry, uncomfortable in chest, do not relax through carrying out breast feeling of distension and oppression, dark tongue quality, white and thin fur, stringy pulse
Carefully.Use the prescription of embodiment one, Radix Bupleuri 30g, Radix Paeoniae Alba 30g, Fructus Aurantii Immaturus 30g, Radix Glycyrrhizae Preparata 24g, Ramulus Cinnamomi 18g, Rhizoma Acori Graminei 15g.
Taking crude drug, add water with the weight ratio of 1:8-10, decoct, make decoction, every day 1 pair, point morning, noon and afternoon take for 3 times.
Taking medicine 14 days, tired and insomnia improves；Continue to take medicine mild hyperaemia tired, forgetful, depressed, forgetful, pharyngeal, pass after February
Joint pain, the transference cure such as the most angry, uncomfortable in chest.After change pill into, continue to strengthen treatment February, cure, follow up a case by regular visits to 1 year not recur.
Case 2, relative, man, 42 years old, people from Zhongmou County, Henan Province.There is major fatigue without obvious inducement in May, 2012, stops
Do not subtract after breath, absent minded, forgetful, it is in a very depressed state, latter end is had a sleepless night, arthralgia, heating, muscle weakness, tired postemphasis.
Above-mentioned symptom sustainable existence, once sought medical advice in the first Affiliated Hospital of Henan university of TCM, and was diagnosed as " chronic fatigue syndrome ", gives
After giving oral vitamin C, compound vitamin B, oryzanol and Chinese medicine BUZHONG YIQI TANG, tired change is inconspicuous, in May, 2013
Come to seek medical advice in inventor through colleague's introduction.Examining and see: tired face, conscious physical fatigue is difficult to resolve, and accompanies forgetful, and night sleeps the best, pharynx
Portion's mild hyperaemia, double knee joint pain, there is heating time conscious, uncomfortable in chest, red tongue, white and thin fur, stringy pulse.Use the group of embodiment two
Decoction, Radix Bupleuri 24g, Radix Paeoniae Alba 24g, Fructus Aurantii Immaturus 24g, Radix Glycyrrhizae Preparata 18g, Ramulus Cinnamomi 15g, Rhizoma Acori Graminei 12g make in side.Every day 1 pair, in point morning
Evening takes for 3 times.Take medicine physical fatigue after February, forgetful, insomnia, pharyngeal congestion, double knee joint pain, heating and the disease such as uncomfortable in chest disappears
Lose.Then change and take granule and take after mixing it with water, continue to strengthen treatment 2 months, thoroughly cure, follow up a case by regular visits to so far, not recur.
Case 3, Fan, man, 50 years old, people from Xinxiang City, Henan Province.In July, 2014, patient occurred lasting tired without obvious inducement
Labor, does not subtracts after rest, absent minded, forgetful, early section insomnia, double knee joint pain, conscious muscle fatigue and weak, Shi Youfa
Heat, tired postemphasis.Above-mentioned symptom sustainable existence, once sought medical advice in Third Affiliated Hospital of Xinxiang Medical Coll, was diagnosed as " confirmed fatigue
Syndrome ", after giving oral vitamin C, compound vitamin B, oryzanol, Shenqi oral liquid and remittance people's renal aid, tired change is failed to understand
Aobvious, come to seek medical advice in inventor upon somebody's introduction in May, 2015.Examining and see: tired face, conscious physical fatigue is difficult to resolve, and accompanies forgetful,
Night sleeps the best, and double knee joint pain has heating time conscious, vexed, uncomfortable in chest, body of the tongue is light red, white and thin fur, stringy pulse.Use embodiment
The prescription of three makes decoction, Radix Bupleuri 18g, Radix Paeoniae Alba 18g, Radix Glycyrrhizae Preparata 18g, Fructus Aurantii Immaturus 18g, Ramulus Cinnamomi 12g, Rhizoma Acori Graminei 12g.Take medicine February
Rear physical fatigue, forgetful, insomnia, double knee joint pain, heating, vexed, disease such as grade uncomfortable in chest disappears.Then change take capsule be administered orally, continue
Continuous after treatment 3 months, thoroughly cures, follows up a case by regular visits to so far, not recur.
Detailed description of the invention
Embodiment one: the Chinese medicine composition of preventing and treating chronic fatigue syndrome, crude drug prescription:
Radix Bupleuri 30g, Radix Paeoniae Alba 30g, Fructus Aurantii Immaturus 30g, Radix Glycyrrhizae Preparata 24g, Ramulus Cinnamomi 18g, Rhizoma Acori Graminei 15g.
Preparation method: take crude drug, adds water with the weight ratio of 1:8-10, decocts, and is brewed into decoction, every day 1 pair, point morning, noon and afternoon 3
Secondary take.
Embodiment two: essentially identical with embodiment one, difference is:
Crude drug prescription: Radix Bupleuri 24g, Radix Paeoniae Alba 24g, Fructus Aurantii Immaturus 24g, Radix Glycyrrhizae Preparata 18g, Ramulus Cinnamomi 15g, Rhizoma Acori Graminei 12g.
Embodiment three: essentially identical with embodiment one, difference is:
Crude drug prescription: Radix Bupleuri 18g, Radix Paeoniae Alba 18g, Radix Glycyrrhizae Preparata 18g, Fructus Aurantii Immaturus 18g, Ramulus Cinnamomi 12g, Rhizoma Acori Graminei 12g.
Embodiment four: essentially identical with embodiment one, difference is:
Crude drug prescription: Radix Bupleuri 12g, Radix Paeoniae Alba 12g, Radix Glycyrrhizae Preparata 12g, Fructus Aurantii Immaturus 12g, Ramulus Cinnamomi 12g, Rhizoma Acori Graminei 6g.
Embodiment five: essentially identical with embodiment one, difference is:
Crude drug prescription: Radix Bupleuri 10g, Radix Paeoniae Alba 10g, Radix Glycyrrhizae Preparata 10g, Fructus Aurantii Immaturus 10g, Ramulus Cinnamomi 5g, Rhizoma Acori Graminei 5g.
Embodiment six: essentially identical with embodiment one, difference is:
Crude drug prescription: Radix Bupleuri 30g, Radix Paeoniae Alba 30g, Radix Glycyrrhizae Preparata 30g, Fructus Aurantii Immaturus 30g, Ramulus Cinnamomi 30g, Rhizoma Acori Graminei 20g.
Claims (4)
1. prevent and treat a Chinese medicine composition for chronic fatigue syndrome, it is characterized in that: this Chinese medicine composition is by following weight portion
Crude drug is made, Radix Bupleuri 10-30 part, Radix Paeoniae Alba 10-30 part, Radix Glycyrrhizae Preparata 10-30 part, Fructus Aurantii Immaturus 10-30 part, Ramulus Cinnamomi 5-30 part, stone Chang
Pu 5-20 part.
The Chinese medicine composition of preventing and treating chronic fatigue syndrome the most according to claim 1, is characterized in that: described Chinese medicine composition
The crude drug of thing is preferably: Radix Bupleuri 10-25 part, Radix Paeoniae Alba 10-25 part, Radix Glycyrrhizae Preparata 10-25 part, Fructus Aurantii Immaturus 10-25 part, Ramulus Cinnamomi 5-25
Part, Rhizoma Acori Graminei 5-15 part.
The Chinese medicine composition of preventing and treating chronic fatigue syndrome the most according to claim 1, is characterized in that: described Chinese medicine composition
The crude drug of thing be preferably: Radix Bupleuri 10-20 part, Radix Paeoniae Alba 10-20 part, Radix Glycyrrhizae Preparata 8-20 part, Fructus Aurantii Immaturus 12-20 part, Ramulus Cinnamomi 9-20 part,
Rhizoma Acori Graminei 6-12 part.
The Chinese medicine composition of preventing and treating chronic fatigue syndrome the most according to claim 1, is characterized in that: described Chinese medicine composition
Thing is decoction, watered pill, capsule or the granule made according to a conventional method.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114010751A (en) * | 2021-12-03 | 2022-02-08 | 冯利 | Chinese medicinal composition for preventing and treating cancer-induced fatigue and cancer-treated fatigue |
-
2016
- 2016-05-10 CN CN201610302751.8A patent/CN105943753A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 谢忠礼，等: ""加味四逆散对慢性应激大鼠额叶5-HT2AR 及其mRNA 表达的影响"", 《中药药理与临床》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114010751A (en) * | 2021-12-03 | 2022-02-08 | 冯利 | Chinese medicinal composition for preventing and treating cancer-induced fatigue and cancer-treated fatigue |
| CN114010751B (en) * | 2021-12-03 | 2022-08-30 | 冯利 | Traditional Chinese medicine composition for preventing and treating cancer-induced fatigue |
| CN114010751B9 (en) * | 2021-12-03 | 2022-11-04 | 冯利 | Traditional Chinese medicine composition for preventing and treating cancer-induced fatigue |
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Application publication date: 20160921 |