CN101966258A - Traditional Chinese medicine for treating diabetic retinopathy - Google Patents

Abstract

The invention discloses a traditional Chinese medicine for treating diabetic retinopathy, belongs to the field of traditional Chinese medicines for treating diabetes, and aims to achieve good effect and quick response. The traditional Chinese medicine is prepared from raw materials of mulberry leaf, pseudoginseng root, rehmannia, lucid ganoderma, Chinese angelica, hedge prinsepia nut and the like. The traditional Chinese medicine has the effects of strengthening the body resistance and reinforcing the body, tonifying qi and nourishing blood and nourishing the liver and improving visual acuity, and has the advantages of obvious effect, exact curative effect and quick response.

Description

The Chinese medicine that a kind of treatment of diabetic retinopathy becomes

Technical field

The invention belongs to the field of Chinese medicines of treatment diabetes.

Background technology

Diabetic renal papillary necrosis is the retinal microvascular pathological changes that diabetes cause, and is a domestic generally acknowledged treatment " difficult problem " at present.The existing Chinese medicine that is intended to the treatment of diabetic retinopathy change, exist some obviously not enough: the one, effect is humbleer, the 2nd, it is slower to take effect, not especially effectively means and channel of western medicine and medical practitioners, retinal hemorrhage dry and astringent to blurred vision, the eyes of alleviating this disease and forming, edema in addition is so that large quantities of patients with diabetic retinopathy constantly develops into " losing one's sight ".

At problem set forth above, the invention provides the Chinese medicine that a kind of treatment of diabetic retinopathy becomes, it is obvious inadequately that it can solve in this type of treatment by Chinese herbs in the past effect, the slower problem that takes effect, effective, instant effect, it is remarkable to have effect, drug effect is definite, the advantage of quick result.

Summary of the invention

The present invention is achieved through the following technical solutions:

1, a kind of Chinese medicine of treatment of diabetic retinopathy change adopts the raw material of Chinese medicine preparation, and filling a prescription is (by weight):

Folium Mori 5-15 part Radix Notoginseng 3-9 part Radix Rehmanniae 6-18 part

Ganoderma 6-18 part Radix Angelicae Sinensis 6-18 part Nux Prinsepiae 6-18 part

The Chinese medicine that this treatment of diabetic retinopathy becomes is made by following method:

(1) by above-mentioned weight ratio, Ganoderma is extracted ganoderan with decoction and alcohol sedimentation technique, technological process is as follows: Ganoderma is broken into graininess, cross 40 mesh sieves →, concentrate → mixed, leave standstill 1012 hours, centrifugal → as to add 75% ethanol with 95% ethanol of 3 times of volumes with 1: 20 hot water (95 ℃) lixiviate → lixiviating solution decompression, precipitate polysaccharide → dry the ganoderan extract fine powder;

(2) by above-mentioned weight ratio, Folium Mori, Radix Rehmanniae, Radix Angelicae Sinensis, Nux Prinsepiae are extracted through conventional water extraction process, make extract extractum fine powder;

(3) by above-mentioned weight ratio, Radix Notoginseng is ground into fine powder, mixes, stir, make Chinese medicine granules, capsule, tablet with above-mentioned (1), (2) two kinds of extract fine powders.

The present invention is according to the folk tradition prescription, and the theory according to traditional Chinese medical science the body resistance strengthening and constitution consolidating, blood circulation promoting and blood stasis dispelling develops meticulously.We think that diabetic renal papillary necrosis is the microangiopathies of diabetic retina in essence at research, and its main diseases is because of being the diabetics hypoimmunity, deficiency of both QI and YIN, the five internal organs are scorching, and the blood network stasis of blood stagnates, blood coagulates, gathers, sticks, and causes blood supply insufficiency, with the passing of time causes amphiblestroid injury.Control and to attach most importance to supplementing QI and nourishing YIN heat clearing away, blood circulation promoting and blood stasis dispelling to set upright.The maximum characteristics of we are to start with from enhancing immunity, and by " removing " and " reparation " effect of immunity, blood clean makes blood no longer sticky, but rich mobile, the retina blood supply is full.This is the key of treatment primary disease.The value of maximum of the present invention just is: do not have at present under the situation that active drug can control in this disease, it can save the vision of thousands of patients with diabetic retinopathy, realize two targets: the one, the microangiopathies of remarkable relieving retina, make it no longer to develop and worsen, eyes " do not lose one's sight ", the 2nd, the microangiopathies of repairing retina makes the whole or big portion of impaired vision obtain " recovery ".We can say that this is a comparatively great invention.Ganoderma, Radix Rehmanniae the body resistance strengthening and constitution consolidating among the we, benefiting QI and nourishing blood, enhancing human body immunity power; Radix Angelicae Sinensis, pseudo-ginseng blood-circulation-invigovating blood stasis dispelling, eliminating stasis to stop pain; Be aided with the Folium Mori dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, nourishing the liver to improve visual acuity; The Nux Prinsepiae wind-dispelling heat-dissipating, nourishing the liver to improve visual acuity.All medicine compatibilities bring out the best in each other, and play the body resistance strengthening and constitution consolidating altogether, benefiting QI and nourishing blood, and blood circulation promoting and blood stasis dispelling, the merit of nourishing the liver to improve visual acuity, effective, instant effect, it is remarkable to have effect, and drug effect is definite, the advantage of quick result.

The specific embodiment

By following embodiment the present invention is done and to specify:

1, get following prescription (weight is unit by gram):

Folium Mori 50 gram Radix Notoginseng 30 gram Radix Rehmanniae 60 grams

Ganoderma 60 gram Radix Angelicae Sinensis 60 gram Nux Prinsepiae 60 grams

Weight is extracted Ganoderma with decoction and alcohol sedimentation technique in accordance with regulations; With conventional water extraction process Folium Mori, Radix Rehmanniae, Radix Angelicae Sinensis, Nux Prinsepiae are extracted, make extract fine powder 58 grams altogether, Radix Notoginseng is ground into fine powder, mix with said extracted thing fine powder, stir, make fine particle, the capsule of packing into No. 0, make 314 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

2, get following prescription (weight is unit by gram):

Folium Mori 100 gram Radix Notoginseng 60 gram Radix Rehmanniae 120 grams

Ganoderma 120 gram Radix Angelicae Sinensis 120 gram Nux Prinsepiae 120 grams

By above-mentioned same method, make 628 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

3, get following prescription (weight is unit by gram):

Folium Mori 150 gram Radix Notoginseng 90 gram Radix Rehmanniae 180 grams

Ganoderma 180 gram Radix Angelicae Sinensis 180 gram Nux Prinsepiae 180 grams

By above-mentioned same method, make 942 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

4, get following prescription (by weight):

7 parts of 3 portions of Radix Rehmanniae of 6 portions of Radix Notoginseng of Folium Mori

7 parts of 7 parts of Nux Prinsepiae of 7 parts of Radix Angelicae Sinensis of Ganoderma

By above-mentioned same method, make Chinese medicinal capsule, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

5, get following prescription (by weight):

17 parts of 7 portions of Radix Rehmanniae of 13 portions of Radix Notoginseng of Folium Mori

17 parts of 17 parts of Nux Prinsepiae of 17 parts of Radix Angelicae Sinensis of Ganoderma

By above-mentioned same method, make Chinese medicinal capsule, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

Clinical data:

The present invention is an example with traditional Chinese medical science diabetic renal papillary necrosis (retinopathy), through 6 routine clinical observations.Selecting the tcm diagnosis diabetic renal papillary necrosis is standard: diabetics is had a dizzy spell, and gum is too much; Binocular dryness, eye socket pain; Visual deterioration, blurred vision; That retina occurs is hemorrhage, edema, ooze out.As above symptom can be made a definite diagnosis.In making a definite diagnosis the object of observation, male's 3 examples, women's 3 examples do not have other serious disease, and the age is 47 years old-76 years old, 62.1 years old mean age.

Efficacy determination:

1, produce effects: gum is normal, eyes Clear and Bright; Binocular dryness disappears, and eyes are comfortable; Blurred vision is alleviated, and vision improves more than 0.1; The white macula that the optical fundus occurs, macula lutea, blood stain quantity reduce, and area dwindles.

2, effective: the dry and astringent disappearance of eyes, blurred vision is alleviated.

3, invalid: the disease no change.

During clinical experiment, except that the antidiabetic drug that diabetics is necessary is taken (medicine is constant, amount is constant) as usual, withdraw other medicines and health nutrient.Taking Chinese medicinal capsule of the present invention, observed 6 months, is a course of treatment.Instructions of taking: every day 2 times, each 3 capsules, every capsules include Chinese medicine fine powder and extract 0.28 gram, warm water delivery service after meal, symptom promptly has alleviation after 1 month, take 6 months after, symptom is obviously improved.6 philtrums of clinical experiment, produce effects 3 people, effective 2 people, invalid 1 people, total effective rate 83.3%.

Claims (1)

1. the Chinese medicine that becomes of a treatment of diabetic retinopathy, it is characterized in that: it is to make with the component of following weight ratio: Folium Mori 5-15 part, Radix Notoginseng 3-9 part, Radix Rehmanniae 6-18 part, Ganoderma 6-18 part, Radix Angelicae Sinensis 6-18 part, Nux Prinsepiae 6-18 part.