CN108904651A - A kind of eyes are releived liquid and preparation method thereof - Google Patents

A kind of eyes are releived liquid and preparation method thereof Download PDF

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CN108904651A
CN108904651A CN201811078237.6A CN201811078237A CN108904651A CN 108904651 A CN108904651 A CN 108904651A CN 201811078237 A CN201811078237 A CN 201811078237A CN 108904651 A CN108904651 A CN 108904651A
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liquid
eyes
releived
preparation
filtrate
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何沛杰
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
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    • A61K31/07Retinol compounds, e.g. vitamin A
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    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536Prunella or Brunella (selfheal)
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    • A61K2236/30Extraction of the material
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    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
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    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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Abstract

It releives liquid and preparation method thereof, including following components by weight percent the invention discloses a kind of eyes:Ginseng 200-320g, wild chrysanthemum 170-200g, cassia seed 200-400g, dandelion 100-200g, witch hazel 40-60g, honeysuckle 40-60g, structure matrimony vine 30-50g, pipewort 30-50g, Prunella vulgaris 10-20g, peppermint 10-20g.Ingredient is Chinese materia medica preparation, and safety is without side-effects, and is combined during the preparation process using flooding and alcohol extraction, and be repeated as many times and extract, and guarantees being fully dissolved out for active principle.The product has safer service performance, without side-effects, has highly application value.

Description

A kind of eyes are releived liquid and preparation method thereof
Technical field
The present invention relates to sight protection technical field, more particularly to a kind of eyes are releived liquid and its preparation side Method.
Background technique
With the development of science and technology these electronic products such as mobile phone, computer are already be unable to do without in daily life, due to Electronic product is used for a long time or be easy to cause asthenopia with eye is of long duration.Asthenopia is a kind of ophthalmology common disease, caused by it Eye it is dry, eye is puckery, eye is sour swollen, blurred vision even visual impairment directly affects the work and life of people.Asthenopia is mainly When usually concentrating to see computer screen due to people, eyes number of winks is reduced, and is caused tears Secretion that should reduce, is dodged simultaneously Caused by bright fluorescent screen intense stimulus eyes.The reason of causing asthenopia mainly include ophthalmic refractive is abnormal, excessive eye is closely sealed, With eye disease, dysplasia of eye, constitution and life factor and age environmental factor etc..
Alleviate the common method of asthenopia at present to be to maintain regular rest eyes, do eye exercises and use eye dropping of eye drops Liquid, first two have certain alleviation visual fatigue, but people work, learning pressure rhythm is fast, do not ensure that regular rest With do eye exercises;And eye dropping of eye drops liquid is mostly the drug of temporary ciliary muscle of releiving mostly, can not eliminate eye from the root Fatigue, it is important that the eye drops in the prior art for alleviating asthenopia contains a variety of chemical addition agents of a large amount of preservative, long Phase use will appear side effect, cause irreversible damage to eyes.
Therefore how to provide a kind of safety the eye drops that can be releived from the root to eyes without side-effects, it is this field Technical staff's urgent problem to be solved.
Summary of the invention
In view of this, releiving liquid the present invention provides a kind of eyes, uses pure Chinese medicinal preparation for component, do not add anyization Reagent is learned, and can solve the problems, such as asthenopia in root.
In order to achieve the above object, the present invention adopts the following technical scheme that:
A kind of eyes are releived liquid, including:Ginseng 200-320g, wild chrysanthemum 170-200g, cassia seed 200-400g, dandelion 100-200g, witch hazel 40-60g, honeysuckle 40-60g, fructus lycii 30-50g, pipewort 30-50g, Prunella vulgaris 10-20g are thin Lotus 10-20g.
Preferably, including following components by weight percent:
Ginseng 250g, wild chrysanthemum 180g, cassia seed 300g, dandelion 150g, witch hazel 50g, honeysuckle 50g, fructus lycii 40g, pipewort 40g, Prunella vulgaris 15g, peppermint 15g.
Further, further include:Vitamin A 0.5-1g and vitamin E 0.5-1g.
Wherein, the main component of ginseng is panaxoside, organic acid, esters, vitamin, sterol etc., adjustable maincenter The excited process and process of inhibition of nervous system improve the adaptability etc. of human body, can nourish optic nerve in the present invention, make Optic nerve is obtained to be loosened;
Flos Chrysanthemi Indici extract is compositae plant mother chrysanthemum Chrysanthemum indicum L., HERBA CHRYSANTHEMI LAVANDULAEFOLII C.boreale Mak. or the capitulum of lavandulaleaf dendranthema herb C.lavandulaefolium (Fisch.) Mak., there is anti-inflammatory, anti-aging, prevent powder Thorn, clearing heat and detoxicating and other effects;
Cassia seed:It is sweet in flavor, bitter, at cold nature;Return liver, large intestine channel, heat-clearing improving eyesight, relax bowel and defecation is used for the puckery pain of hot eyes, The more tears of photophobia, headache and dizziness, mesh is secretly unknown, constipation;
Dandelion:Clearing heat and detoxicating, diuresis dissipating bind can treat acute conjunctivitis;
Witch hazel:It is a variety of such as the adjustable sebum secretion of Ellagtannin and Hamamlitannin, tool to include tannin matter Moisturizing and Milk Protein promote lymph blood circulation, can specially overcome morning eye bladder and black eye, have effect that is calm, pacifying Fruit, remove eye pouch, have releive, restrain, antibacterial, the effect of anti-aging;
Honeysuckle:It is cold in nature, it is sweet in flavor, enter lung, the heart, stomach meridian, there is clearing heat and detoxicating, anti-inflammatory efficacy;
Fructus lycii:Fructus lycii is sweet natured, enters liver and kidney channel, has effects that replenishing the vital essence and the blood, nourishing liver and kidney, benefiting shrewd head, Kidney deficiency and liver, essence and blood cannot be gone up help the diseases curative effects such as the dim-sighted, hypopsia of eyes caused by mesh it is further preferred that;
Pipewort:It is acrid flavour, sweet, it is mild-natured.Return liver, lung channel, dispelling wind and heat from the body will move back screen tomorrow.For wind-heat hot eyes, swell and ache shy It is bright, screen of looking unfamiliar film, headache due to pathogenic wind-heat;
Prunella vulgaris:(scientific name:Prunella vulgaris L), contain triterpenoid saponin, glucoside member is oleanolic acid, is also contained Free oleanolic acid, ursolic acid, rutin, hyperin, along caffeic acid, anti-caffeic acid, tannin, volatile oil, a small amount of biology Alkali and water soluble salt (predominantly potassium chloride), anthocyanin, d- camphor, d- fennel fruit containing delphinidin and Cyanidin in flower spike Mattress ketone musk etc., it is cold in nature, it is bitter, pungent;Return liver, gallbladder channel.Major function:It relieves inflammation or internal heat, improving eyesight, dissipating bind, detumescence, for red eye, swell pain, mesh Pearl nyctalgia, headache and dizziness, scrofula, goiter, swelling and pain;Thyroid Gland Swell, scrofula, the proliferation of mammary gland, hypertension;
Peppermint:Peppermint is Chinese conventional Chinese medicine, and young tender stem tip can make vegetable edible, and herb can be used as medicine again, and cure cold fever laryngalgia, Headache, conjunctival congestion with ophthalmalgia, myalgia, itchy skin with rubella, the diseases such as measles without adequate eruption are furthermore also effective to carbuncle, subcutaneous ulcer, scabies, tinea, dermatitis rhus, Peppermint contains menthol, the substance can fresh breath and have a variety of pharmacological properties, can be relieved abdominal pain, gall-bladder problem such as spasm, also have There are antisepsis and sterilization, diuresis, resolving sputum, stomach invigorating and aid digestion and other effects.
It acts synergistically between above-mentioned plurality of Chinese, alleviates asthenopia from the root, and without side-effects, there is very high answer With value.
It releives the preparation method of liquid it is another object of the present invention to provide a kind of eyes, specifically includes following steps:
(1) by ginseng 200-320g, wild chrysanthemum 170-200g, cassia seed 200-400g, dandelion 100-200g, witch hazel 40-60g, honeysuckle 40-60g, fructus lycii 30-50g, pipewort 30-50g, Prunella vulgaris 10-20g, peppermint 10-20g are cleaned and are dried It is dry, it is ground into powdery later, obtains mixed powder;
(2) mixed powder obtained in the step (1) is subjected to flooding, then filtered, collect filtrate and filter is concentrated Liquid retains filter residue;
(3) filter residue in the step (2) is subjected to alcohol extraction, then filtered, collect filtrate and filtrate is concentrated;
(4) concentration filtrate obtained in the step (2) is mixed with concentration filtrate obtained in the step (3) And be stirred by ultrasonic and releive liquid to get eyes, sterilization packaging is carried out later.
Preferably, concentrate is being mixed while vitamin A 0.5-1g and vitamin E 0.5- is added in the step (4) 1g is sufficiently mixed.
The beneficial effect of above-mentioned optimal technical scheme is:Vitamin A can maintain normal vision function, and vitamin E can anti-inflammatory And promote blood circulation, have between above-mentioned traditional Chinese medicinal components and cooperates with facilitation.
Preferably, the partial size of the mixed powder ground in the step (1) is 250-300 mesh.
The beneficial effect of above-mentioned optimal technical scheme is:The partial size can guarantee that active principle quickly and effectively dissolves out, again It is convenient for filtering.
Preferably, the flooding in the step (1) uses sterile water, and alcohol extraction uses anhydrous second in the step (2) Alcohol.
The beneficial effect of above-mentioned optimal technical scheme is:Sterile water avoids miscellaneous bacteria from polluting product, guarantees that product relaxes The quality of slow liquid, while ethyl alcohol is nontoxic and has low volatility, is easily isolated.
Preferably, the step (1) and the step (2) alternately and repeatedly carry out 3 times or more.
The beneficial effect of above-mentioned optimal technical scheme is:Guarantee that the active principle in traditional Chinese medicine ingredients dissolves out completely, is promoted former Expect utilization rate.
Preferably, the concentration filtrate in the step (1) and the step (2) is using heating concentration, heating temperature 50- 70℃。
The beneficial effect of above-mentioned optimal technical scheme is:Guarantee that concentration quickly and effectively carries out while high temperature being avoided to extract Active principle in liquid.
Preferably, sterilization carries out pasteurize after sterilizing using TRANSIENT HIGH TEMPERATURE again in the step (4).
The beneficial effect of above-mentioned technical proposal is:Guarantee to avoid long-time high temperature sterilization to effective group while sterilization is thorough Divide and damages.
In summary technical solution, the opposite and prior art, the beneficial effects of the invention are as follows:Provide a kind of use in pure Medicament extract is that the eyes of active principle are releived liquid, can relieving eye strain from the root, and add, use without chemical products Safety is without side-effects, and preparation process is easy, has very high production and application value.
Specific embodiment
The following is a clear and complete description of the technical scheme in the embodiments of the invention, it is clear that described embodiment Only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, the common skill in this field Art personnel every other embodiment obtained without making creative work belongs to the model that the present invention protects It encloses.
Embodiment 1
Using the component of following weight:Ginseng 200g, wild chrysanthemum 170g, cassia seed 200g, dandelion 100g, witch hazel 40g, honeysuckle 40g, fructus lycii 30g, pipewort 30g, Prunella vulgaris 10g, peppermint 10g.
Preparation uses following steps:
(1) by ginseng 200g, wild chrysanthemum 170g, cassia seed 200g, dandelion 100g, witch hazel 40g, honeysuckle 40g, Chinese holly Matrimony vine 30g, pipewort 30g, Prunella vulgaris 10g, peppermint 10g are cleaned and are dried, and are ground into the powdery of 250-300 mesh later, are obtained mixed Close medicinal powder;
(2) mixed powder obtained in step (1) is subjected to sterile flooding, then filtered, collect filtrate and 50-70 DEG C Heating concentration filtrate, retains filter residue;
(3) filter residue in step (2) is subjected to alcohol steep, then filtered, collect filtrate and 50-70 DEG C of heating concentration filter Liquid;
(4) step (2) and (3) 3 times are repeated, will be concentrated obtained in concentration filtrate obtained in step (2) and step (3) Filtrate is mixed and is stirred by ultrasonic to be releived liquid to get eyes, carries out sterilization packaging later.
In order to advanced optimize above scheme, in step (4) concentrate is mixed be added simultaneously vitamin A 0.5-1g with Vitamin E 0.5-1g is sufficiently mixed.
Embodiment 2
Using the component of following weight:Ginseng 320g, wild chrysanthemum 200g, cassia seed 400g, dandelion 200g, witch hazel 60g, honeysuckle 60g, fructus lycii 50g, pipewort 50g, Prunella vulgaris 20g, peppermint 20g.
Preparation uses following steps:
(1) by ginseng 320g, wild chrysanthemum 200g, cassia seed 400g, dandelion 200g, witch hazel 60g, honeysuckle 60g, Chinese holly Matrimony vine 50g, pipewort 50g, Prunella vulgaris 20g, peppermint 20g are cleaned and are dried, and are ground into the powdery of 250-300 mesh later, are obtained mixed Close medicinal powder;
(2) mixed powder obtained in step (1) is subjected to sterile flooding, then filtered, collect filtrate and 50-70 DEG C Heating concentration filtrate, retains filter residue;
(3) filter residue in step (2) is subjected to alcohol steep, then filtered, collect filtrate and 50-70 DEG C of heating concentration filter Liquid;
(4) step (2) and (3) 3 times are repeated, will be concentrated obtained in concentration filtrate obtained in step (2) and step (3) Filtrate is mixed and is stirred by ultrasonic to be releived liquid to get eyes, carries out sterilization packaging later.
In order to advanced optimize above scheme, in step (4) concentrate is mixed be added simultaneously vitamin A 0.5-1g with Vitamin E 0.5-1g is sufficiently mixed.
Embodiment 3
Using the component of following weight:Ginseng 250g, wild chrysanthemum 180g, cassia seed 300g, dandelion 150g, witch hazel 50g, honeysuckle 50g, fructus lycii 40g, pipewort 40g, Prunella vulgaris 15g, peppermint 15g.
Preparation uses following steps:
(1) by ginseng 250g, wild chrysanthemum 180g, cassia seed 300g, dandelion 150g, witch hazel 50g, honeysuckle 50g, Chinese holly Matrimony vine 40g, pipewort 40g, Prunella vulgaris 15g, peppermint 15g are cleaned and are dried, and are ground into the powdery of 250-300 mesh later, are obtained mixed Close medicinal powder;
(2) mixed powder obtained in step (1) is subjected to sterile flooding, then filtered, collect filtrate and 50-70 DEG C Heating concentration filtrate, retains filter residue;
(3) filter residue in step (2) is subjected to alcohol steep, then filtered, collect filtrate and 50-70 DEG C of heating concentration filter Liquid;
(4) step (2) and (3) 3 times are repeated, will be concentrated obtained in concentration filtrate obtained in step (2) and step (3) Filtrate is mixed and is stirred by ultrasonic to be releived liquid to get eyes, carries out sterilization packaging later.
In order to advanced optimize above scheme, in step (4) concentrate is mixed be added simultaneously vitamin A 0.5-1g with Vitamin E 0.5-1g is sufficiently mixed.
Comparative example 1:
It is releived liquid using eyes conventional on the market.
Measure of merit:
Effect survey is carried out to the consistent subject of eye fatigue degree degree using embodiment 1-3 and the product of comparative example 1 Examination, it is as a result as follows
It is tested by the above results it is found that the resulting product of technical solution of the present invention is taken as, to alleviation and radical cure eye Fatiguability has good effect, and effect is in rising trend, and uses the comparative example 1 of market product to asthenopia situation With temporary improvement result, but after 30 days, eyes fatiguability situation has no improvement.
In conclusion technical solution provided by the invention can effectively alleviate asthenopia and eradicate eyes tire easily symptom, And it is safe without side-effects.
Each embodiment in this specification is described in a progressive manner, the highlights of each of the examples are with other The difference of embodiment, the same or similar parts in each embodiment may refer to each other.For device disclosed in embodiment For, since it is corresponded to the methods disclosed in the examples, so being described relatively simple, related place is said referring to method part It is bright.
The foregoing description of the disclosed embodiments enables those skilled in the art to implement or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, as defined herein General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, of the invention It is not intended to be limited to the embodiments shown herein, and is to fit to and the principles and novel features disclosed herein phase one The widest scope of cause.

Claims (10)

  1. The liquid 1. a kind of eyes are releived, which is characterized in that including following components by weight percent:
    Ginseng 200-320g, wild chrysanthemum 170-200g, cassia seed 200-400g, dandelion 100-200g, witch hazel 40-60g, gold Honeysuckle flower 40-60g, fructus lycii 30-50g, pipewort 30-50g, Prunella vulgaris 10-20g, peppermint 10-20g.
  2. The liquid 2. a kind of eyes according to claim 1 are releived, which is characterized in that including following components by weight percent:
    Ginseng 250g, wild chrysanthemum 180g, cassia seed 300g, dandelion 150g, witch hazel 50g, honeysuckle 50g, fructus lycii 40g, Pipewort 40g, Prunella vulgaris 15g, peppermint 15g.
  3. 3. being releived liquid according to a kind of described in any item eyes of right 1-2, which is characterized in that further include:Vitamin A 0.5-1g and Vitamin E 0.5-1g.
  4. The preparation method of liquid 4. a kind of eyes are releived, which is characterized in that include the following steps:
    (1) by ginseng 200-320g, wild chrysanthemum 170-200g, cassia seed 200-400g, dandelion 100-200g, witch hazel 40- 60g, honeysuckle 40-60g, fructus lycii 30-50g, pipewort 30-50g, Prunella vulgaris 10-20g, peppermint 10-20g are cleaned and are dried, It is ground into powdery later, obtains mixed powder;
    (2) mixed powder obtained in the step (1) is subjected to flooding, then filtered, collect filtrate and filtrate is concentrated, protected Stay filter residue;
    (3) filter residue in the step (2) is subjected to alcohol extraction, then filtered, collect filtrate and filtrate is concentrated;
    (4) concentration filtrate obtained in the step (2) is mixed and is surpassed with concentration filtrate obtained in the step (3) Sound stirring is releived liquid to get eyes, carries out sterilization packaging later.
  5. The preparation method of liquid 5. a kind of eyes according to claim 4 are releived, which is characterized in that in the step (4) Concentrate is mixed while vitamin A 0.5-1g is added and vitamin E 0.5-1g is sufficiently mixed.
  6. 6. a kind of preparation method of draft eyesight maintenance liquid according to claim 4, which is characterized in that the step (1) The partial size of the mixed powder of middle grinding is 250-300 mesh.
  7. The preparation method of liquid 7. a kind of eyes according to claim 4 are releived, which is characterized in that in the step (1) Flooding uses sterile water, and alcohol extraction uses dehydrated alcohol in the step (2).
  8. The preparation method of liquid 8. a kind of eyes according to claim 4 are releived, which is characterized in that the step (1) and institute Step (2) is stated alternately and repeatedly to carry out 3 times or more.
  9. The preparation method of liquid 9. a kind of eyes according to claim 4 are releived, which is characterized in that the step (1) and institute The concentration filtrate in step (2) is stated using heating concentration, heating temperature is 50-70 DEG C.
  10. The preparation method of liquid 10. a kind of eyes according to claim 4 are releived, which is characterized in that killed in the step (4) Bacterium carries out pasteurize after sterilizing using TRANSIENT HIGH TEMPERATURE again.
CN201811078237.6A 2018-09-12 2018-09-12 A kind of eyes are releived liquid and preparation method thereof Pending CN108904651A (en)

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CN110812438A (en) * 2019-11-21 2020-02-21 崔全昌 Traditional Chinese medicine composition for relieving visual fatigue, preparation method and application

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Application publication date: 20181130