CN104606367A - Traditional Chinese medicine eye drop for treating liver and kidney insufficiency myopia, and preparation method thereof - Google Patents
Traditional Chinese medicine eye drop for treating liver and kidney insufficiency myopia, and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to the field of Chinese herbal preparations, and particularly relates to a traditional Chinese medicine eye drop for treating liver and kidney insufficiency myopia, and a preparation method for the eye drop. The traditional Chinese medicine eye drop comprises the pharmaceutical ingredients of grossy privet fruit, desertliving cistanche, cynomorium songaricum, mulberry seeds, red ginseng, semen cuscutae, prepared rehmannia roots, poria with hostwood, astragalus membranaceus, Chinese angelica, szechuan lovage rhizome, gingko, pearl powder, chrysanthemum, honeysuckle, semen cassiae, roses, peppermint, Chinese wolfberry, vitamin A and vitamin E. The eye drop is prepared by adopting the modern advanced medicine pharmaceutical technology, has the effects of nourishing liver and kidney, calming liver and suppressing yang, removing liver-fire for improving eyesight, reducing fever and clearing heat-fire, and alleviating spasm and removing eye opacity, can treat myopia caused by liver and kidney insufficiency, is reasonable in the pharmaceutical ingredient compatibility, obvious in curative effect, high in safety performance, free of negative and side effects, low in cost and worthy of wide popularization and application.
Description
Technical field
The invention belongs to field of traditional Chinese, be specifically related to one and treat bathomorphic traditional Chinese medicine eye drops of deficiency of the liver and kindey type and preparation method thereof.
Background technology
Human eye is as plus lens, and when dormant state, its diopter (diopter, D) is 58.64D, can reach 70.57D during maximal regulated.Myopia is that ophthalmic refractive power is excessively strong, when regulating, ophthalmic is entered from the parallel rays beyond 5 meters, after becoming the convex excessive flexion of crystalline lens, macula retinae portion center recess can not be focused on, and drop on before retina, form a dispersion ring, so that things at a distance cannot be seen clearly.In addition, bathomorphic axis oculi is usually longer, and myopia degree is higher, and axis oculi is longer.
The myopia of modern medicine, Ancient Chinese claims " the nearly timid disease far away of energy ", and the Qing Dynasty's yellow front yard mirror is shown " order is through great achievement " and begun to claim " myopia ", of the same name with the present.East Asia is global near-sighted sickness rate superlatively district, and China, Japan and Singapore in recent years suffer from near-sighted number and rises sharply.According to ministry of Health of China, Ministry of Education's joint investigation display, current Chinese student's myopia sickness rate, close to 60%, is only second to Japan, occupies the 2nd, the world; Patient numbers, more than 6,000 ten thousand, occupies first of the world, because near-sighted blinding person reaches 300,000 people.Students in middle and primary schools' rate of myopia is 34.6%, and high school student reaches 70%.Hesperian near-sighted sickness rate also rising, about three point of one American suffers from myopia, and there is the children with myopia of 50%12 years old in Sweden, to they 18 years old time, this ratio more reaches to 70%.
Environmental factors and inherited genetic factors play important function in the morbidity of juvenile myopia.In environmental factors, long-time near work is the main cause causing adolescent myopia.The treatment of modern medicine to primary disease divides operation and No operation two kinds, because teenager is in growth and development stage, the dioptric system of eye is not yet stable, operative treatment its first-selection non-.Non-operative treatment mainly contains wears glasses, applies cycloplegic etc., but curative effect is not all affirmed.
Motherland's medical science is thought, the ametropia oculopathy such as myopia are all often owing to using eyesight improper, overworked eyes; Or the motive is weak, spleen kidney deficiency; Or stagnation of liver-QI is depressed, hyperactivity of fire caused by deficiency of YIN; Or the hepatic and renal YIN deficiency, first reporting caused by deficiency, is congenital heredity and the coefficient result of acquired environment factor.Therefore treatment is cloudy when pressing down with invigorating YANG, temperature compensation heart spleen kidney yang gas is main, holds concurrently with dispersing the stagnated live-QI to relieve the stagnation of QI, promoting flow of QI and blood, nourishing the liver to improve visual acuity, enrich and benefit essence and blood, nourishing YIN to lower pathogenic fire.
Especially deficiency of the liver and kindey type myopia sickness rate in myopia is the highest, and how because of natural endowment deficiency, nurture is bad, works with one's mind and overtaxes one's nerves, and heart-yang consumes, and makes conscience kidney deficiency, causes eyeball pearl paramophia and form.
Summary of the invention
According to above the deficiencies in the prior art, the invention provides one and treat bathomorphic traditional Chinese medicine eye drops of deficiency of the liver and kindey type and preparation method thereof, it is evident in efficacy, safe and reliable, have no side effect, there is wide potential applicability in clinical practice.
One of the present invention treats the bathomorphic traditional Chinese medicine eye drops of deficiency of the liver and kindey type, according to weight parts, comprise following ingredient: Fructus Ligustri Lucidi 20 ~ 30 parts, Herba Cistanches 20 ~ 30 parts, Herba Cynomorii 20 ~ 30 parts, Fructus Mori 20 ~ 30 parts, Radix Ginseng Rubra 15 ~ 20 parts, Semen Cuscutae 20 ~ 30 parts, Radix Rehmanniae Preparata 20 ~ 30 parts, Poria cum Radix Pini 15 ~ 20 parts, the Radix Astragali 5 ~ 10 parts, Radix Angelicae Sinensis 2 ~ 3 parts, Rhizoma Chuanxiong 3 ~ 5 parts, Semen Ginkgo 5 ~ 8 parts, Margarita powder 2 ~ 3 parts, Flos Chrysanthemi 10 ~ 20 parts, Flos Lonicerae 5 ~ 8 parts, Semen Cassiae 10 ~ 15 parts, Flos Rosae Rugosae 5 ~ 8 parts, Herba Menthae 3 ~ 5 parts, Fructus Lycii 10 ~ 20 parts, vitamin A 0.1 ~ 1 part and vitamin E 0.1 ~ 1 part.
Wherein, preferred version is as follows:
According to weight parts, comprise following ingredient: Fructus Ligustri Lucidi 25 parts, Herba Cistanches 25 parts, Herba Cynomorii 25 parts, Fructus Mori 25 parts, Radix Ginseng Rubra 18 parts, Semen Cuscutae 25 parts, Radix Rehmanniae Preparata 25 parts, Poria cum Radix Pini 18 parts, the Radix Astragali 8 parts, Radix Angelicae Sinensis 2 parts, Rhizoma Chuanxiong 4 parts, Semen Ginkgo 6 parts, Margarita powder 2 parts, Flos Chrysanthemi 15 parts, Flos Lonicerae 6 parts, Semen Cassiae 12 parts, Flos Rosae Rugosae 7 parts, Herba Menthae 4 parts, Fructus Lycii 15 parts, vitamin A 0.5 part and vitamin E 1 part.
The preparation method of the bathomorphic traditional Chinese medicine eye drops for the treatment of deficiency of the liver and kindey type of the present invention, during preparation, carry out according to following steps:
(1) first Fructus Ligustri Lucidi, Herba Cistanches, Herba Cynomorii, Fructus Mori, Radix Ginseng Rubra, Semen Cuscutae, Radix Rehmanniae Preparata, Poria cum Radix Pini, the Radix Astragali, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Semen Ginkgo, Margarita powder, Flos Chrysanthemi, Flos Lonicerae, Semen Cassiae, Flos Rosae Rugosae, Herba Menthae, Fructus Lycii are added water 5000 milliliters, slow fire boils 1 hour, gets filtrate;
(2) residue adds water 5000 milliliters again, and slow fire boils 1 hour, twice filtrate is merged;
(3) above-mentioned filtrate is concentrated into 125 milliliters, adds the ethanol mixing that 375 milliliters of mass fractions are 95% after cooling, place after 24 hours with filter paper filtering;
(4), after filtrate being waved most or recovery ethanol, vitaminize A and vitamin E powder, stir evenly adding distil water to 1000 ~ 5000 milliliter again and obtain medicinal liquid;
(5) adjust medicinal liquid and be equivalent to the osmotic pressure that mass fraction is the sodium chloride of 0.8 ~ 1.2%, adding preservative agent cyanogen Mercury difluoride. in medicinal liquid, wherein, the volume ratio of cyanogen Mercury difluoride. and medicinal liquid is 1:1500, then adjusts pH value to 7.0 with the sodium hydroxide that mass fraction is 10%;
(6) last medicinal liquid is through filter paper filtering, seals, autoclave sterilization, subpackage 8 mls/branch.
During use, every day 3 ~ 5 times, each 1 ~ 2.
Pharmacology analysis:
Fructus Ligustri Lucidi: sweet is bitter, flat.Return liver, kidney channel.For the poor vision of the hepatic and renal YIN deficiency, visual deterioration, early whitening of beard and hair, soreness of waist tinnitus and fever due to yin deficiency etc.This product energy tonifying liver kidney yin, but the efficacy of a drug is gentle, slowly must get effect.
Herba Cistanches: sweet, salty, temperature.Return kidney, large intestine channel.Kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation.For sexual impotence, infertile, soreness of the waist and knees, muscles and bones is unable, dryness of the intestine constipation.
Herba Cynomorii: sweet, temperature.Return spleen, kidney, large intestine channel.Kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation.Soft for waist knee joint flaccidity, sexual impotence spermatorrhea, dryness of the intestine constipation.
Fructus Mori: sweet; Acid; Cold in nature.Return liver, kidney channel.Nourishing YIN and benefiting blood; Promote the production of body fluid; Intestine moistening.Having a dizzy spell of main deficiency of the liver and kindey and blood deficiency damage of essence; Soreness of waist tinnitus; Early whitening of beard and hair; Insomnia and dreamful sleep; Tianjin wound is thirsty; Quench one's thirst; Dryness of the intestine constipation.
Radix Ginseng Rubra: sweet, micro-hardship, temperature.Return spleen, lung, heart channel.Strongly invigorating primordial QI, multiple arteries and veins takes off admittedly, nourishing qi to stop.For weak body and prostration, cold extremities faint pulse, QI failing to control blood, metrostaxis; Heart failure, cardiogenic shock.
Semen Cuscutae: sweet, temperature.Return liver,kidney,spleen warp.Nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.For impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen is suffered from a deficiency of the kidney and is rushed down; Externally treating leucoderma.
Radix Rehmanniae Preparata: sweet, tepor.Return liver, kidney channel.Nourishing YIN and supplementing blood, beneficial essence fills out marrow.For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, and metrostaxis is dizzy, tinnitus, early whitening of beard and hair.
Poria cum Radix Pini: nature and flavor are sweet, light flat.There are the functions such as eliminating dampness by diuresis, spleen invigorating, mind calming.For phlegm retention, edema, dysuria, have loose bowels, cardiopalmus, dizzy.
The Radix Astragali: gas in tonifying the spleen and stomach, and can yang-energy be promoted, QI and blood can arrive brain smoothly, put forward shake spirit, brains is clear, and can strengthen the ability of body surface resistance to colds.
Radix Angelicae Sinensis: enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.Cure mainly all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.
Rhizoma Chuanxiong: containing ligustrazine, ligustrazine energy coronary artery dilator, increases coronary artery blood flow, improves the blood oxygen supply of cardiac muscle, and reduces the oxygen consumption of cardiac muscle; The expansible cerebrovascular of ligustrazine, reduces vascular resistance, significantly increases brain and LBF amount, improves microcirculation; Can surface activity of blood platelet be reduced, suppress platelet aggregation, the formation of pre-preventing thrombosis; The neutral compound low dose of contained ferulic acid promotes, heavy dose of suppression uterine smooth muscle; Water decoction has sedation to animal central nervous systems, and has obvious and lasting hypotensive effect; The absorption of fracture local hematoma can be accelerated, promote callus formation; There is the effect of vitamin antagonist E shortage; Multiple bacillus can be suppressed; There are antihistaminic and choleretic effect.
Semen Ginkgo: property is put down, sweet in the mouth is pained, slightly poisonous; Enter lung, kidney channel.Folium Ginkgo extract principle active component is flavonoid and bilobalide-like biological active substances, referred to as Folium Ginkgo extract (GBE), ocular angiogenesis can be expanded, suppress platelet aggregation, reduce the permeability of blood capillary, antioxidation, scavenging activated oxygen, improve the activity of SOD, improve microcirculation with this.
Margarita powder: Margarita powder has the effect of heat-clearing and toxic substances removing, can clearing away liver-fire.The liver being in charge of the eyes, the raw nebula of hot-tempered then order, blurred vision.Find through research, the selenium in Margarita powder can strengthen the conduction of optic nerve, improves eyesight status simultaneously; Zinc in trace element can promote the axonal transport of optic nerve, improves metabolism and the function of retina and retinal pigment epithelium.The Pharmacopoeia of the People's Republic of China describes: " Margarita has the function of improving eyesight removing nebula, cures mainly the raw nebula of order ", so Margarita powder becomes " ophthalmology panacea " by a lot of scholar.
Flos Chrysanthemi: loose wind heat clearing away, suppressing the hyperactive liver improving eyesight.For anemopyretic cold, have a headache dizzy, conjunctival congestion and swelling pain, eyes is dim-sighted.
Flos Lonicerae: cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treat effect of wind, cures mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.The diseases such as it is dizzy for giddy, xerostomia is done yearningly, hyperhidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle furuncle, erysipelas, parotitis, suppurative tonsillitis all have certain curative effect.
Semen Cassiae: the function of tool clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.Removing heat from the liver is longer than by raw Semen Cassiae, and intestine moistening is dry.For conjunctival congestion and swelling pain, constipation.
Flos Rosae Rugosae: sweet and slightly bitter taste, slightly warm in nature, returns liver, spleen, stomach warp.Turbid clearly and not, and and violent, easing the affected liver is waken up stomach, and thin gas is invigorated blood circulation, and a surname is logical stops up stagnant and absolutely not pungent temperature is just dry fraud.
Herba Menthae: young tender stem point can make vegetable edible, and herb can be used as medicine again, cure cold heating laryngalgia, and headache, conjunctival congestion with ophthalmalgia, myalgia, skin rubella is scratched where it itches, the diseases such as measles without adequate eruption, also effective to carbuncle, cellulitis, scabies, tinea, dermatitis rhus in addition.Herba Menthae contains menthol, and this material can fresh breath have the multiple property of medicine, can alleviate stomachache, gallbladder problem as spasm, also have antisepsis and sterilization, diuresis, reduces phlegm, stomach invigorating and the effect such as aid digestion.
Fructus Lycii: cure mainly nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.Containing 14 seed amino acids in Fructus Lycii, and containing special dietary compositions such as betanin, beautiful another name for Sichuan Province flavin, physalins, make it have outstanding health-care effect.Fructus Lycii contains the required nutrient substance of abundant carotene, multivitamin and the healthy eye such as calcium, ferrum, therefore has the merit of improving eyesight, is commonly called as " bright eye ".What ancient Chinese medicine doctor treatment deficiency of liver-blood, deficiency of kidney-YIN caused looks thing duskization and nyctalopia, usually uses Fructus Lycii.Famous prescription " QIJU DIHUANG WAN " is just key agents with Fructus Lycii.
Vitamin A: also known as retinol (its aldehyde derivatives retinal) or antiophthalmic factor, be a unsaturated monohydric alcohol with alicyclic ring, comprising retinol1, the A2 two kinds in animal food source, is that a class has the bioactive material of retinol.Retinol1 is stored in the liver of mammal and saltwater fish more, and dehydroretinol is often stored in the liver of fresh-water fishes.Because the expression activitiy of dehydroretinol is low, so usually said vitamin A refers to retinol1.Vitamin A maintains normal visual performance, and vitamin A is sufficient, then soon and completely, dark adaptation is short for recovery time in the regeneration of rhodopsin.
Vitamin E: vitamin E can suppress the lipid peroxidation in eye lens to react, and makes end slightly vasodilation, improves blood circulation, pre-myopia prevention occurs and development.
Eye drop of the present invention adopts modern advanced medical pharmaceutical technology to make, and has nourishing the liver and kidney, suppressing the hyperactive liver and subsiding YANG, liver heat removing and eyesight improving, clearing away heat-fire, the effect of spasmolytic removing nebula, is used for the treatment of deficiency of the liver and kindey type myopia symptom, selected medical material compatibility is suitable, evident in efficacy, security performance is high, has no side effect, cheap, should be widely promoted application.
Outcome measure:
1.1 physical data
The present invention is light to 100 examples, medium myopia patient carries out clinical observation treatment, wherein age reckling 8 years old, the maximum 32 years old, 16 years old mean age; Man 54 example, female 46 example.Get rid of the caused myopia of heredity.
Wherein low myopia is within 300 degree; Medium myopia is 300-600 degree, and cardinal symptom is for seeing that distant objects is smudgy.
1.2 Therapeutic Method
Therapeutic Method: use collyrium of the present invention, instillation ophthalmic, every day 3 ~ 5 times, each 1 ~ 2.
Period in a medicine is avoided pungent.
Eye exercises 5-10 minute effect is done in medication every day after 1 hour better.
1.3 efficacy assessment standard
Cure: see that the smudgy Clinical symptom and sign that waits of thing far away disappears, more than vision restoration to 1.0.
Effective: see that the smudgy basic or large portion of Clinical symptom and sign that waits of thing far away disappears, vision does not reach 1.0, but improves more than 0.2.
Effective: see that the clinical symptoms such as thing far away is smudgy are clearly better or take a turn for the better, vision does not reach 1.0, increases, but improves below 0.2.
Invalid: Clinical symptom and sign is without improvement, and Index for examination has no improvement.
1.4 therapeutic effect:
Cure 88 examples, account for 88.0%, effective 6 examples, account for 6.0%, and effective 3 examples, account for 3.0%, and invalid 3 examples, account for 6.0%, total effective rate 97.0%.
Inventor to above-mentioned 88 examples " healing " follow-up of patients 1 year, recurrence 6 example.Visible collyrium of the present invention has good therapeutic effect in treatment myopia.
1.5 model cases:
Case 1: Zhang, female, 15 years old, school middle school student, naked vision left eye <0.5, right eye <0.6.Give and collyrium of the present invention, every day three times, each 1 ~ 2, according to subject treatment method, within 10 days, alleviate, correct defects of vision after 30 days as eyes 1.3.Pay a return visit without recurrence after 12 months.
Case 2: Song, man, 17 years old, school middle school student, naked vision left eye <0.2, right eye <0.12.Give and collyrium of the present invention, every day three times, each 1 ~ 2, according to subject treatment method, within 10 days, alleviate, correct defects of vision after 30 days as eyes 1.0.Pay a return visit without recurrence after 12 months.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1:
One treats the bathomorphic traditional Chinese medicine eye drops of deficiency of the liver and kindey type, according to weight parts, comprise following ingredient: Fructus Ligustri Lucidi 25 parts, Herba Cistanches 25 parts, Herba Cynomorii 25 parts, Fructus Mori 25 parts, Radix Ginseng Rubra 18 parts, Semen Cuscutae 25 parts, Radix Rehmanniae Preparata 25 parts, Poria cum Radix Pini 18 parts, the Radix Astragali 8 parts, Radix Angelicae Sinensis 2 parts, Rhizoma Chuanxiong 4 parts, Semen Ginkgo 6 parts, Margarita powder 2 parts, Flos Chrysanthemi 15 parts, Flos Lonicerae 6 parts, Semen Cassiae 12 parts, Flos Rosae Rugosae 7 parts, Herba Menthae 4 parts, Fructus Lycii 15 parts, vitamin A 0.5 part and vitamin E 1 part.
Embodiment 2:
Embodiment 1 is prepared according to following steps:
(1) first Fructus Ligustri Lucidi, Herba Cistanches, Herba Cynomorii, Fructus Mori, Radix Ginseng Rubra, Semen Cuscutae, Radix Rehmanniae Preparata, Poria cum Radix Pini, the Radix Astragali, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Semen Ginkgo, Margarita powder, Flos Chrysanthemi, Flos Lonicerae, Semen Cassiae, Flos Rosae Rugosae, Herba Menthae, Fructus Lycii are added water 5000 milliliters, slow fire boils 1 hour, gets filtrate;
(2) residue adds water 5000 milliliters again, and slow fire boils 1 hour, twice filtrate is merged;
(3) above-mentioned filtrate is concentrated into 125 milliliters, adds the ethanol mixing that 375 milliliters of mass fractions are 95% after cooling, place after 24 hours with filter paper filtering;
(4), after filtrate being waved most or recovery ethanol, vitaminize A and vitamin E powder, stir evenly adding distil water to 1000 ~ 5000 milliliter again and obtain medicinal liquid;
(5) adjust medicinal liquid and be equivalent to the osmotic pressure that mass fraction is the sodium chloride of 1.0%, adding preservative agent cyanogen Mercury difluoride. in medicinal liquid, wherein, the volume ratio of cyanogen Mercury difluoride. and medicinal liquid is 1:1500, then adjusts pH value to 7.0 with the sodium hydroxide that mass fraction is 10%;
(6) last medicinal liquid is through filter paper filtering, seals, autoclave sterilization, subpackage 8 mls/branch.
Claims (3)
1. the bathomorphic traditional Chinese medicine eye drops for the treatment of deficiency of the liver and kindey type, it is characterized in that according to weight parts, comprise following ingredient: Fructus Ligustri Lucidi 20 ~ 30 parts, Herba Cistanches 20 ~ 30 parts, Herba Cynomorii 20 ~ 30 parts, Fructus Mori 20 ~ 30 parts, Radix Ginseng Rubra 15 ~ 20 parts, Semen Cuscutae 20 ~ 30 parts, Radix Rehmanniae Preparata 20 ~ 30 parts, Poria cum Radix Pini 15 ~ 20 parts, the Radix Astragali 5 ~ 10 parts, Radix Angelicae Sinensis 2 ~ 3 parts, Rhizoma Chuanxiong 3 ~ 5 parts, Semen Ginkgo 5 ~ 8 parts, Margarita powder 2 ~ 3 parts, Flos Chrysanthemi 10 ~ 20 parts, Flos Lonicerae 5 ~ 8 parts, Semen Cassiae 10 ~ 15 parts, Flos Rosae Rugosae 5 ~ 8 parts, Herba Menthae 3 ~ 5 parts, Fructus Lycii 10 ~ 20 parts, vitamin A 0.1 ~ 1 part and vitamin E 0.1 ~ 1 part.
2. the bathomorphic traditional Chinese medicine eye drops for the treatment of deficiency of the liver and kindey type according to claim 1, it is characterized in that according to weight parts, comprise following ingredient: Fructus Ligustri Lucidi 25 parts, Herba Cistanches 25 parts, Herba Cynomorii 25 parts, Fructus Mori 25 parts, Radix Ginseng Rubra 18 parts, Semen Cuscutae 25 parts, Radix Rehmanniae Preparata 25 parts, Poria cum Radix Pini 18 parts, the Radix Astragali 8 parts, Radix Angelicae Sinensis 2 parts, Rhizoma Chuanxiong 4 parts, Semen Ginkgo 6 parts, Margarita powder 2 parts, Flos Chrysanthemi 15 parts, Flos Lonicerae 6 parts, Semen Cassiae 12 parts, Flos Rosae Rugosae 7 parts, Herba Menthae 4 parts, Fructus Lycii 15 parts, vitamin A 0.5 part and vitamin E 1 part.
3. a preparation method for the bathomorphic traditional Chinese medicine eye drops for the treatment of deficiency of the liver and kindey type according to claim 1, when it is characterized in that preparation, carry out according to following steps:
(1) first Fructus Ligustri Lucidi, Herba Cistanches, Herba Cynomorii, Fructus Mori, Radix Ginseng Rubra, Semen Cuscutae, Radix Rehmanniae Preparata, Poria cum Radix Pini, the Radix Astragali, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Semen Ginkgo, Margarita powder, Flos Chrysanthemi, Flos Lonicerae, Semen Cassiae, Flos Rosae Rugosae, Herba Menthae, Fructus Lycii are added water 5000 milliliters, slow fire boils 1 hour, gets filtrate;
(2) residue adds water 5000 milliliters again, and slow fire boils 1 hour, twice filtrate is merged;
(3) above-mentioned filtrate is concentrated into 125 milliliters, adds the ethanol mixing that 375 milliliters of mass fractions are 95% after cooling, place after 24 hours with filter paper filtering;
(4), after filtrate being waved most or recovery ethanol, vitaminize A and vitamin E powder, stir evenly adding distil water to 1000 ~ 5000 milliliter again and obtain medicinal liquid;
(5) adjust medicinal liquid and be equivalent to the osmotic pressure that mass fraction is the sodium chloride of 0.8 ~ 1.2%, adding preservative agent cyanogen Mercury difluoride. in medicinal liquid, wherein, the volume ratio of cyanogen Mercury difluoride. and medicinal liquid is 1:1500, then adjusts pH value to 7.0 with the sodium hydroxide that mass fraction is 10%;
(6) last medicinal liquid is through filter paper filtering, seals, autoclave sterilization, subpackage 8 mls/branch.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104983957A (en) * | 2015-07-07 | 2015-10-21 | 王红伟 | Eye care solution |
| CN105288053A (en) * | 2015-12-02 | 2016-02-03 | 北京林业大学 | Woods Chinese herbal medicine recipe for preventing and treating children shortsightedness and preparation method of recipe |
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| CN102188604A (en) * | 2010-03-09 | 2011-09-21 | 贺光民 | Medicament for treating myopia and presbyopia |
| CN104055841A (en) * | 2014-07-05 | 2014-09-24 | 庄成龙 | Medicine composition for treating and preventing myopia |
| CN104248716A (en) * | 2014-09-10 | 2014-12-31 | 青岛新视界眼科医院 | Compound eye drops and preparation method thereof |
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2015
- 2015-01-13 CN CN201510016470.1A patent/CN104606367A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102188604A (en) * | 2010-03-09 | 2011-09-21 | 贺光民 | Medicament for treating myopia and presbyopia |
| CN104055841A (en) * | 2014-07-05 | 2014-09-24 | 庄成龙 | Medicine composition for treating and preventing myopia |
| CN104248716A (en) * | 2014-09-10 | 2014-12-31 | 青岛新视界眼科医院 | Compound eye drops and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104983957A (en) * | 2015-07-07 | 2015-10-21 | 王红伟 | Eye care solution |
| CN105288053A (en) * | 2015-12-02 | 2016-02-03 | 北京林业大学 | Woods Chinese herbal medicine recipe for preventing and treating children shortsightedness and preparation method of recipe |
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Application publication date: 20150513 |