CN110302283A - A kind of Chinese medicine composition for nursing breast nursing - Google Patents
A kind of Chinese medicine composition for nursing breast nursing Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/86—Violaceae (Violet family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention belongs to breast-nursing technical fields, especially a kind of Chinese medicine composition for nursing period nursing, is made of raw material from the following weight: 3-5 parts of wormwood stostes, 5-10 parts of essential oils, 2-4 portions of dandelions, 0.5-1 portions of viola mandshuricas, 1-2 portions of honeysuckles, 2-3 parts of Fructus Liquidambaris, the 1-3 parts of seeds of cowherb, 2-4 parts of luffa extracting solutions.Chinese medicine composition used in the present invention has effects that clearing heat and detoxicating, dispersing swelling and dissipating binds, promotes lactation, swollen breasts, mazoitis caused by can preventing and treating because of galactostasis；It can promote the secretion of milk again.
Description
Technical field
The invention belongs to breast-nursing technical field, especially a kind of Chinese medicine composition for nursing period nursing.
Background technique
Nursing period refers to postpartum puerpera with the period of the milk feeding infant of oneself, exactly starts lactation to stopping lactation
This period；Generally it is about 10 months to 1 year or so.Initial stage after parturient childbirth is influenced by certain factors, and part puerpera is conscious
No interior milk or milk amount are reduced, and just abandon lactation；Or due to lacking lactation experience, will not breast-nursing, cause galactosis slow,
Breast amount is insufficient or since milk silts up obstructed, milk smoulders are blocking, cause the symptoms such as swollen breasts, mazoitis, not only cause mother
The interruption that cream is fed, and return puerpera and bring very big physiology and do not accommodate psychological pressure, seriously affect the body of mother and baby
Health；Therefore, breast-nursing is the key that delivery woman in lactation period nursing.
Since the nursing of nursing breast affects the health of baby, which has limited many care drugs or medicinal materials
It uses；Therefore, studying the care drug harmless to mother and baby is the key that newborn breast-nursing, and the country is protected about breast at present
The research of drug is managed, but these drugs are usually distending pain and mastoptosis, the coarse relaxation of skin etc. caused by preventing and treating milk
The effect of aspect cannot secrete with adjusting milk well；Easily cause recurrence.As application No. is CN201410520814.8
A kind of medicament for controlling acute mastitis containing Semen Vaccariae of patent disclosure, by and component be made: concha meretricis seu cylinae, Semen Vaccariae, blueness
Each 10 grams of skin, raw each 10 grams of Radix Astragali, party, 30-45 grams of dandelion, each 6 grams of the stem pith of the rice-paper plant, radix bupleuri, tangerine pith, Radix Curcumae, rhizoma nardostachyos, CORTEX MAGNOLIAE OFFICINALIS from Sichuan of China,
Each 10 grams of cornu cerve degelatinatum, honeysuckle, tangerine seed, 15 grams of Fructus Liquidambaris, 12-15 grams of luffa, each 15-20 grams of spina gleditsiae, fritillaria thunbergii, gold and silver
18-30 grams of rattan of flower, 3 grams of licorice, the present invention has the effect of clearing heat and detoxicating, activating microcirculation and removing stasis medicinal, the newborn dissipating bind that disappears, especially acute mastitis from the beginning of
With lump disease person.The patent is but right for galactostasis, nipple damage, acute purulent mammitis caused by syndrome of liver-stomach heat
Do not shown in the adjustment effect of lactation mechanism, and the medicament be it is for oral administration, therapeutic effect is slow.
Summary of the invention
In order to solve the above technical problems existing in the prior art, researcher of the present invention passes through the research and development of many years and faces
Bed experiment carries out screening study with numerous Chinese medicines, and also carries out the impact analysis of different factors to medicinal material treatment process, proposes
A kind of Chinese medicine composition for nursing breast nursing, is realized particular by following technical scheme:
A kind of Chinese medicine composition for nursing breast nursing, is made of raw material from the following weight: 3-5 parts of wormwoods are former
Liquid, 5-10 part essential oil, 2-4 portions of dandelions, 0.5-1 portions of viola mandshuricas, 1-2 portions of honeysuckles, 2-3 parts of Fructus Liquidambaris, 1-3 parts of kings do not stay
Row, 2-4 parts of luffa extracting solutions.
Preferably, the Chinese medicine composition for nursing breast nursing, is made of raw material from the following weight: 3
Part wormwood stoste, 8 parts of essential oils, 2.5 portions of dandelions, 0.6 portion of viola mandshurica, 1.2 portions of honeysuckles, 2.4 parts of Fructus Liquidambaris, 1.5 parts of kings
Do not stay row, 3 parts of luffa extracting solutions.
Preferably, the preparation of the wormwood stoste: after wormwood is smashed to pieces, 10 times of water soaked overnight is added, centrifugation takes
Clear liquid to obtain the final product.
Preferably, the preparation of the luffa extracting solution: after luffa is cut into small pieces, being added 6 times of water and decoct 2 times,
It decocts 2 times every time, merges 2 times and decoct obtained filtrate.
Preferably, the essential oil is made of tea tree ethereal oil, Peppermint essential oil by the weight ratio mixing of 2:1.
Preferably, the preparation method of the Chinese medicine composition for nursing breast nursing, includes the following steps:
(1) each raw material is weighed by the above parts by weight, Fructus Liquidambaris, the seed of cowherb, dandelion, viola mandshurica, honeysuckle is mixed
It closes, 4-5 times of water is added and decocts 1-2h, obtains an extracting solution, a filter residue, it is spare；
(2) luffa extracting solution, wormwood stoste are mixed, a filter residue is added and stirs evenly, is first put into hot environment
4-5h is extracted, places into and extracts 2-3h in low temperature environment, filters, obtains secondary filter residue and admixing medical solutions；
(3) secondary filter residue is taken advantage of into cold crushing, 30 DEG C or so of warm water is added and decocts 20-30min, filtering obtains secondary mention
Take liquid；
(4) extracting solution is uniformly mixed with secondary raffinate, is concentrated into specific gravity d=1.05-1.10, it is after cooling and mixed
Medical fluid, essential oil mixing are closed, ultrasonic wave high-shear emulsion machine internal emulsification is put into, obtains missible oil finished product.
Preferably, the step (2), hot environment refer to that temperature is 40-50 DEG C of environment, and low temperature environment to temperature is 2-4
DEG C environment.
Preferably, the step (3), secondary filter residue are crushed to 16-20 mesh.
Preferably, the step (4), temperature when emulsification is 40-45 DEG C, time 1.2-1.5h.
The Chinese medicine that the present invention selects has effects that following:
Wormwood: it Wen Jing, dries, cold dispelling, hemostasis, anti-inflammatory, relieving asthma, cough-relieving, miscarriage prevention, antiallergy.
Dandelion: clearing heat and detoxicating, diuresis dissipating bind；Main treatment acute mastitis, adenolymphitis, scrofula, boil poisonous soreness are acute
Conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infections.
Viola mandshurica: clearing heat and detoxicating；Cure mainly jaundice, dysentery, mazoitis, red eye, swell pain, pharyngitis；External application control traumatic injury,
Carbuncle swells, venomous snake bite.Flavonoid glycosides and organic acid contained by viola mandshurica to gold-coloured staphylococci, pig Pasteurella, Escherichia coli,
Streptococcus and salmonella have stronger bacteriostasis.
Honeysuckle: clearing heat and detoxicating, anti-inflammatory, qi-restoratives treats wind；Cure mainly disease under turgor, warm disease heating, heat toxin large carbuncle and tumour etc.
Disease.Can be used for dizziness, thirst, sweating and boring, enteritis, bacillary dysentery, morbilli, pneumonia, encephalitis, epidemic meningitis, acute mastitis,
The diseases such as septicemia, ecphyaditis, skin infection, ulcer boils, erysipelas, parotitis, suppurative tonsillitis.
Fructus Liquidambaris: dispelling, collateral-activating, Li Shui, promoting menstruation；For treating arthralgia, numb spasm, edema swelling, cream is few,
Menostasis.
The effect of seed of cowherb: blood circulation, lower cream are reduced swelling, inducing diuresis for treating strangurtia；For menostasis, dysmenorrhea, agalactia, acute mastitis
Swelling and pain, the puckery pain of stranguria.
Luffa: dredging collateral, promoting blood circulation, wind-dispelling；For numbness pain muscular constricture, distending pain in the chest and hypochondrium, alactation.
Compared with prior art, the beneficial effects of the present invention are:
The present invention selects Fructus Liquidambaris, the seed of cowherb, luffa collocation to use, and has the effect of promoting lactation, preventing galactostasis；
Wormwood, dandelion, viola mandshurica, honeysuckle collocation use, and have clearing heat and detoxicating, dispersing swelling and dissipating binds, prevent and treat the effect of mazoitis；Peppermint
Essential oil has the effect of adjusting sebum secretion, shares with tea tree ethereal oil, can prevent cracked nipple, promotes chap wound healing,
Breast can be made to hold elasticity of skin simultaneously.All medicines share facilitates nursing period the effect of playing clearing heat and detoxicating, dispersing swelling and dissipating binds altogether, promote lactation
Breast-nursing.And there is no any tool irritation medicinal material in Chinese medicine composition, any chemical classes cream is also not added in preparation process
Agent has no toxic side effect, harmless to mother and baby.
Specific embodiment
It is limited below with reference to specific embodiment technical solution of the present invention is further, but claimed
Range is not only limited to made description.
Embodiment 1
Component: 3 parts of wormwood stostes, 5 parts of essential oils, 2 portions of dandelions, 0.5 portion of viola mandshurica, 1 portion of honeysuckle, 2 parts of Fructus Liquidambaris,
1 part of seed of cowherb, 2 parts of luffa extracting solutions.
The preparation of the wormwood stoste: after wormwood is smashed to pieces, 10 times of water soaked overnight is added, centrifugation takes supernatant i.e.
?.
The preparation of the luffa extracting solution: after luffa is cut into small pieces, 6 times of water is added and decocts 2 times, decocts every time
2 times, merges 2 times and decoct obtained filtrate.
The essential oil is made of tea tree ethereal oil, Peppermint essential oil by the weight ratio mixing of 2:1.
The preparation method of the Chinese medicine composition for nursing breast nursing, includes the following steps:
(1) each raw material is weighed by the above parts by weight, Fructus Liquidambaris, the seed of cowherb, dandelion, viola mandshurica, honeysuckle is mixed
It closes, 4-5 times of water is added and decocts 1-2h, obtains an extracting solution, a filter residue, it is spare；
(2) luffa extracting solution, wormwood stoste are mixed, a filter residue is added and stirs evenly, is first put into 40-50 DEG C of ring
4-5h is extracted in border, places into 2-4 DEG C of environment and extracts 2-3h, is filtered, is obtained secondary filter residue and admixing medical solutions；
(3) by secondary filter residue take advantage of it is cold be crushed to 16-20 mesh, 30 DEG C or so of warm water is added and decocts 20-30min, filtering obtains
Obtain secondary raffinate；
(4) extracting solution is uniformly mixed with secondary raffinate, is concentrated into specific gravity d=1.05-1.10, it is after cooling and mixed
Medical fluid, essential oil mixing are closed, ultrasonic wave high-shear emulsion machine internal emulsification is put into, maintains 40-45 DEG C, emulsify 1.2-1.5h, obtain cream
Oily finished product.
Embodiment 2
Component: 3 parts of wormwood stostes, 8 parts of essential oils, 2.5 portions of dandelions, 0.6 portion of viola mandshurica, 1.2 portions of honeysuckles, 2.4 parts
Fructus Liquidambaris, 1.5 parts of seeds of cowherb, 3 parts of luffa extracting solutions.
The preparation of the wormwood stoste: after wormwood is smashed to pieces, 10 times of water soaked overnight is added, centrifugation takes supernatant i.e.
?.
The preparation of the luffa extracting solution: after luffa is cut into small pieces, 6 times of water is added and decocts 2 times, decocts every time
2 times, merges 2 times and decoct obtained filtrate.
The essential oil is made of tea tree ethereal oil, Peppermint essential oil by the weight ratio mixing of 2:1.
The preparation method of the Chinese medicine composition for nursing breast nursing, includes the following steps:
(1) each raw material is weighed by the above parts by weight, Fructus Liquidambaris, the seed of cowherb, dandelion, viola mandshurica, honeysuckle is mixed
It closes, 4-5 times of water is added and decocts 1-2h, obtains an extracting solution, a filter residue, it is spare；
(2) luffa extracting solution, wormwood stoste are mixed, a filter residue is added and stirs evenly, is first put into 40-50 DEG C of ring
4-5h is extracted in border, places into 2-4 DEG C of environment and extracts 2-3h, is filtered, is obtained secondary filter residue and admixing medical solutions；
(3) by secondary filter residue take advantage of it is cold be crushed to 16-20 mesh, 30 DEG C or so of warm water is added and decocts 20-30min, filtering obtains
Obtain secondary raffinate；
(4) extracting solution is uniformly mixed with secondary raffinate, is concentrated into specific gravity d=1.05-1.10, it is after cooling and mixed
Medical fluid, essential oil mixing are closed, ultrasonic wave high-shear emulsion machine internal emulsification is put into, maintains 40-45 DEG C, emulsify 1.2-1.5h, obtain cream
Oily finished product.
Embodiment 3
Component: 4 parts of wormwood stostes, 8 parts of essential oils, 2.5 portions of dandelions, 0.6 portion of viola mandshurica, 1.5 portions of honeysuckles, 2.5 parts
Fructus Liquidambaris, 2 parts of seeds of cowherb, 3 parts of luffa extracting solutions.
The preparation of the wormwood stoste: after wormwood is smashed to pieces, 10 times of water soaked overnight is added, centrifugation takes supernatant i.e.
?.
The preparation of the luffa extracting solution: after luffa is cut into small pieces, 6 times of water is added and decocts 2 times, decocts every time
2 times, merges 2 times and decoct obtained filtrate.The essential oil is pressed the weight ratio mixing group of 2:1 by tea tree ethereal oil, Peppermint essential oil
At.
The preparation method of the Chinese medicine composition for nursing breast nursing, includes the following steps:
(1) each raw material is weighed by the above parts by weight, Fructus Liquidambaris, the seed of cowherb, dandelion, viola mandshurica, honeysuckle is mixed
It closes, 4-5 times of water is added and decocts 1-2h, obtains an extracting solution, a filter residue, it is spare；
(2) luffa extracting solution, wormwood stoste are mixed, a filter residue is added and stirs evenly, is first put into 40-50 DEG C of ring
4-5h is extracted in border, places into 2-4 DEG C of environment and extracts 2-3h, is filtered, is obtained secondary filter residue and admixing medical solutions；
(3) by secondary filter residue take advantage of it is cold be crushed to 16-20 mesh, 30 DEG C or so of warm water is added and decocts 20-30min, filtering obtains
Obtain secondary raffinate；
(4) extracting solution is uniformly mixed with secondary raffinate, is concentrated into specific gravity d=1.05-1.10, it is after cooling and mixed
Medical fluid, essential oil mixing are closed, ultrasonic wave high-shear emulsion machine internal emulsification is put into, maintains 40-45 DEG C, emulsify 1.2-1.5h, obtain cream
Oily finished product.
Embodiment 4
Component: 5 parts of wormwood stostes, 10 parts of essential oils, 4 portions of dandelions, 1 portion of viola mandshurica, 2 portions of honeysuckles, 3 parts of Fructus Liquidambaris, 3
Part seed of cowherb, 4 parts of luffa extracting solutions.
The preparation of the wormwood stoste: after wormwood is smashed to pieces, 10 times of water soaked overnight is added, centrifugation takes supernatant i.e.
?.
The preparation of the luffa extracting solution: after luffa is cut into small pieces, 6 times of water is added and decocts 2 times, decocts every time
2 times, merges 2 times and decoct obtained filtrate.The essential oil is pressed the weight ratio mixing group of 2:1 by tea tree ethereal oil, Peppermint essential oil
At.
The preparation method of the Chinese medicine composition for nursing breast nursing, includes the following steps:
(1) each raw material is weighed by the above parts by weight, Fructus Liquidambaris, the seed of cowherb, dandelion, viola mandshurica, honeysuckle is mixed
It closes, 4-5 times of water is added and decocts 1-2h, obtains an extracting solution, a filter residue, it is spare；
(2) luffa extracting solution, wormwood stoste are mixed, a filter residue is added and stirs evenly, is first put into 40-50 DEG C of ring
4-5h is extracted in border, places into 2-4 DEG C of environment and extracts 2-3h, is filtered, is obtained secondary filter residue and admixing medical solutions；
(3) by secondary filter residue take advantage of it is cold be crushed to 16-20 mesh, 30 DEG C or so of warm water is added and decocts 20-30min, filtering obtains
Obtain secondary raffinate；
(4) extracting solution is uniformly mixed with secondary raffinate, is concentrated into specific gravity d=1.05-1.10, it is after cooling and mixed
Medical fluid, essential oil mixing are closed, ultrasonic wave high-shear emulsion machine internal emulsification is put into, maintains 40-45 DEG C, emulsify 1.2-1.5h, obtain cream
Oily finished product.
1 low dose group of comparative example
Comparative example 1 the difference from embodiment 1 is that component is different, be 3 parts of wormwood stostes, 5 parts of essential oils, 2 portions of dandelions,
0.5 portion of viola mandshurica, 1 portion of honeysuckle, 2 parts of Fructus Liquidambaris, 1 part of seed of cowherb, 2 parts of luffa extracting solutions；Remaining process is identical.
2 high dose group of comparative example
Comparative example 2 is that component is different from the difference of embodiment 4, is 5 parts of wormwood stostes, 10 parts of essential oils, 4 parts of dandelions, 1
Part viola mandshurica, 2 portions of honeysuckles, 3 parts of Fructus Liquidambaris, 3 parts of seeds of cowherb, 4 parts of luffa extracting solutions；Remaining process is identical.
Comparative example 3
For comparative example 3 the difference from embodiment 1 is that not having wormwood stoste in component, remaining is identical.
Comparative example 4
For comparative example 4 the difference from embodiment 1 is that not having essential oil in component, remaining is identical.
Comparative example 5
For comparative example 5 the difference from embodiment 1 is that not having wormwood stoste, essential oil in component, remaining is identical.
Comparative example 6
Comparative example 6 is directly by one without step (2), step (3) the difference from embodiment 1 is that preparation method is different
Secondary extracting solution is concentrated into specific gravity d=1.05-1.10, it is cooling after with wormwood stoste, luffa extracting solution, essential oil mixing and emulsifying.Water
Decoction, emulsification condition are same as Example 1.
Comparative example 7
Comparative example 7 the difference from embodiment 1 is that preparation method is different, be directly by road the logical, seed of cowherb, dandelion,
It after viola mandshurica, honeysuckle co-grinding to 20 mesh, adds water to cook, obtains decoction liquor；Decoction liquor is concentrated into specific gravity d=again
1.05-1.10, it is cooling after with wormwood stoste, luffa extracting solution, essential oil mixing and emulsifying.Water decoction, emulsification condition and embodiment 1
It is identical.
Experimental study:
1, it is real for acute skin irritation skin irritation test: to randomly select the small white mouse that 55 sizes are close, healthy
It tests, the weight of small white mouse is 18-22g, before administration for 24 hours shaves off the hair of small white mouse backbone two sides.It will remove the skin of gross area
It is divided into two sides, side skin keeps complete；Other side skin is gently rubbed with sand paper, to hurt epidermis, does not hurt corium, slight oozing of blood
For degree.
The small white mouse handled well is divided into 11 groups, every group 5, is given using made of embodiment 1-4 and comparative example 1-7
Whole skin and the coating of damaged skin small white mouse back hair removal section, are administered, continuous 7d for 24 hours, remove the remaining drug in small white mouse back,
There is erythema and oedema situation in local application position after observation is discontinued, the small white mouse back after medication without erythema and oedema situation,
Stimulate the reaction scoring is 0, shows the Chinese traditional medicine composition without apparent irritation.
2, zoopery: preparation prepared by research embodiment 1-4 and comparative example 1-7 is to SD rat acute breast blood stasis mould
The influence of type Hemorheology index, as shown in table 1
Influence of 1 preparation of table to SD rat acute breast Blood stasis model Hemorheology index
As known from Table 1, embodiment 1-4, comparative example 1-7 be compared with Blood stasis model group, whole blood contrast viscosity, erythrocyte sedimentation rate, red thin
Born of the same parents, hematocrit are significantly reduced, and embodiment 1-4 group reducing effect becomes apparent from, and illustrate that preparation prepared by the present invention has work
The effect of distending pain, is eliminated in blood stagnation resolvation.
3, clinical trial:
3.1 patient datas: in May, 2016 is chosenIn August, 2017 gives a birth in provincial, and municipal level hospital and has swollen breasts
Puerpera 100, it is classified as experimental group (embodiment example 1-4 made preparation is smeared) and control group (warm water's applying hot soaks).It is real
Test group 80, average age 27.42 years old, control group 20, average age 27.2 years old.2 groups in age, parity and postpartum hemorrhage amount
Etc. no difference of science of statistics (p > 0.05), be comparable.2 groups of puerperal breasts hardness and distending pain judgment criteria are consistent, breast
Hardness and distending pain indexing are as follows: I degree of touching such as lip, II degree of touching such as nose, III degree of touching such as forehead.2 groups of breast hardness and swollen
The distribution of pain indexing constitutes no difference of science of statistics.
3.2 method
Experimental group: experimental group is divided into 1-4 group, and every group of 20 people are externally applied to cream using the made preparation of embodiment 1-4 respectively
15min, each 1 time of daily morning and afternoon, then cooperation correctly milking posture milk ejection are gently massaged in room；5d is used continuously.
Control group: being soaked towel with warm water, and temperature is 40 DEG C or so hot compresses in postpartum double cream 15min, daily up and down
Noon each 1 time, then cooperation correctly milking posture milk ejection；Continuously 5d is applied with hot towel.
Over the course for the treatment of, the C&T of breast is observed at any time, and listens attentively to the main suit of puerpera.
3.3 observation index:
(1) fully recover: breast is without distending pain, and breast is interior, and without lump, milk ejection is unobstructed, and breast hardness is I degree；
(2) effective: swollen breasts are substantially reduced, and lump in breast diameter is less than 2cm, and breast hardness is I degree；
(3) effectively: swollen breasts improve, and lump in breast diameter is 2-5cm or so, and breast hardness is II degree；
(4) invalid: without improvement, lump in breast diameter is greater than 5cm for treatment rear udder attachment distending pain and breast hardness.
3.4 experimental result
2 curative effect of table
| Group | Number of cases | Recovery from illness | It is effective | Effectively | In vain | It is efficient |
| Experimental group 1 | 20 | 12 | 4 | 4 | 0 | 100% |
| Experimental group 2 | 20 | 14 | 3 | 3 | 0 | 100% |
| Experimental group 3 | 20 | 14 | 3 | 2 | 1 | 95% |
| Experimental group 4 | 20 | 10 | 3 | 7 | 0 | 100% |
| Experimental group | 80 | 50 | 13 | 16 | 1 | 98.75% |
| Control group | 20 | 8 | 3 | 6 | 3 | 85% |
It is important to point out that, above embodiments and test example are only limitted to do further technical solution of the present invention herein
Elaboration and understanding, should not be understood as it is further to technical solution of the present invention limited, what those skilled in the art made
The innovation and creation of non-protruding essential characteristics and marked improvement still fall within protection category of the invention.
Claims (9)
1. a kind of Chinese medicine composition for nursing breast nursing, which is characterized in that be made of raw material from the following weight: 3-
5 parts of wormwood stostes, 5-10 parts of essential oils, 2-4 portions of dandelions, 0.5-1 portions of viola mandshuricas, 1-2 portions of honeysuckles, 2-3 parts of Fructus Liquidambaris, 1-
3 parts of seeds of cowherb, 2-4 parts of luffa extracting solutions.
2. the Chinese medicine composition for nursing breast nursing as described in claim 1, which is characterized in that described is used to feed
The Chinese medicine composition of newborn phase breast-nursing, is made of raw material from the following weight: 3 parts of wormwood stostes, 8 parts of essential oils, 2.5 parts of Pu public affairs
English, 0.6 portion of viola mandshurica, 1.2 portions of honeysuckles, 2.4 parts of Fructus Liquidambaris, 1.5 parts of seeds of cowherb, 3 parts of luffa extracting solutions.
3. the Chinese medicine composition for nursing breast nursing as described in claim 1, which is characterized in that the wormwood stoste
Preparation: after wormwood is smashed to pieces, 10 times of water soaked overnight is added, centrifugation takes supernatant to obtain the final product.
4. the Chinese medicine composition for nursing breast nursing as described in claim 1, which is characterized in that the luffa mentions
It takes the preparation of liquid: after luffa is cut into small pieces, 6 times of water is added and decocts 2 times, decocts 2 times every time, merges 2 decoctions and obtained
Obtain filtrate.
5. the Chinese medicine composition for nursing breast nursing as described in claim 1, which is characterized in that the essential oil is by tea
It sets essential oil, Peppermint essential oil and mixes composition by the weight ratio of 2:1.
6. the preparation method of the Chinese medicine composition as described in any one in claim 1-5 for nursing breast nursing, special
Sign is, includes the following steps:
(1) each raw material is weighed by the above parts by weight, Fructus Liquidambaris, the seed of cowherb, dandelion, viola mandshurica, honeysuckle is mixed, added
Enter 4-5 times of water and decoct 1-2h, obtains an extracting solution, a filter residue, it is spare；
(2) luffa extracting solution, wormwood stoste are mixed, a filter residue is added and stirs evenly, is first put into hot environment and extracts
4-5h is placed into and is extracted 2-3h in low temperature environment, and filtering obtains secondary filter residue and admixing medical solutions；
(3) secondary filter residue is taken advantage of into cold crushing, 30 DEG C or so of warm water is added and decocts 20-30min, filtering obtains secondary raffinate；
(4) extracting solution is uniformly mixed with secondary raffinate, is concentrated into specific gravity d=1.05-1.10, it is cooling after with mix medicine
Liquid, essential oil mixing, are put into ultrasonic wave high-shear emulsion machine internal emulsification, obtain missible oil finished product.
7. the preparation method for the Chinese medicine composition of nursing breast nursing as claimed in claim 6, which is characterized in that institute
It states step (2), hot environment refers to that temperature is 40-50 DEG C of environment, and low temperature environment refers to that temperature is 2-4 DEG C of environment.
8. the preparation method for the Chinese medicine composition of nursing breast nursing as claimed in claim 6, which is characterized in that institute
Step (3) are stated, secondary filter residue is crushed to 16-20 mesh.
9. the preparation method for the Chinese medicine composition of nursing breast nursing as described in claim 1, which is characterized in that institute
It states step (4), temperature when emulsification is 40-45 DEG C, time 1.2-1.5h.
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