CN110302089A - Eye mask and preparation method thereof containing micromolecule polypeptide - Google Patents
Eye mask and preparation method thereof containing micromolecule polypeptide Download PDFInfo
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- CN110302089A CN110302089A CN201910556708.8A CN201910556708A CN110302089A CN 110302089 A CN110302089 A CN 110302089A CN 201910556708 A CN201910556708 A CN 201910556708A CN 110302089 A CN110302089 A CN 110302089A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The invention discloses a kind of eye mask and preparation method thereof containing micromolecule polypeptide; wherein contain Matrixyl -4, Argireline, -4 four kinds of acetyl group tetrapeptide -5, myristoyl pentapeptide micromolecule polypeptides; reasonably combined plant extracts, moisturizer and other adjuvants; without additives such as essence, pigment, preservatives; micromolecule polypeptide ingredient in the present invention naturally safely, be easy to be absorbed by the skin; collocation plant extracts; with more significant moisture-keeping crease-shedding effect; and it is dense to can be the more fine length of eyelashes; keep binocular more obvious bright, it is more charming.
Description
Technical field
The present invention relates to a kind of eye mask and preparation method thereof containing micromolecule polypeptide.
Background technique
In recent years, with the continuous improvement of people's living standards, the demand to the function skin care item in daily cosmetics is sent out
Exhibition rapidly, the problem of to the maintenance of skin at people's growing interest.
Eye circumference microgroove is common cosmetic problem, and in daily life, computer radiation, dust, vehicle exhaust etc. are all adding
The aging of fast skin, and the wherein most sensitive fragility of eye circumference skin, while its profile variation is also the most obvious.Along with the age
Increase and external environment problem, the skin of circumference of eyes breed small microgroove because of water shortage and deposit a large amount of melanin, serious shadow
Ring face aesthetic feeling.
Eye mask is common eye skin care item, but at present most of eye mask product be equipped with synthetics non-woven fabrics,
The materials such as jelly formula, biological fiber composition, this kind of eye mask have that nutrient absorption is slow, expensive and beauty is imitated in use
Not the problems such as fruit is not good enough, and current eye mask function focuses mostly in moisturizing, and function is more single.Therefore, a kind of ingredient collocation is closed
Reason, the more preferable absorbed eye mask of effective component energy accord with the demands of the market very much.
Summary of the invention
The purpose of the present invention is to provide a kind of eye mask and preparation method thereof containing micromolecule polypeptide.
The technical solution used in the present invention is:
A kind of eye mask containing micromolecule polypeptide, wherein containing: micromolecule polypeptide, plant extracts, parahydroxyacet-ophenone, sugar
Base trehalose, dipotassium glycyrrhizinate, glycerol, butanediol, Sodium Hyaluronate, niacinamide, cyclomethicone, poly dimethyl silicon
Oxygen alkane/vinyl dimethicone cross polymer, hydrolecithin, carbohydrate isomer, citric acid, citric acid
Sodium, 1,2- hexylene glycol, thickener, pH adjusting agent, water.
Further, the mass fraction of each raw material are as follows: 8-60 parts of micromolecule polypeptide, 2-20 parts of plant extracts, to hydroxyl
0.5-5 parts of acetophenone, 1-10 parts of glycosyl trehalose, 0.05-0.5 parts of dipotassium glycyrrhizinate, 5-20 parts of glycerol, 5-20 parts of butanediol,
0.05-0.5 parts of Sodium Hyaluronate, 1-10 parts of niacinamide, 0.15-3 parts of cyclomethicone, dimethyl silicone polymer/second
0.15-3 parts of alkenyl Dimethicone Crosspolymer, 0.2-4 parts of hydrolecithin, carbohydrate isomer 0.15-1.5
Part, 0.15-1.5 parts of citric acid, 0.2-2 parts of sodium citrate, 0.5-5 parts of 1,2- hexylene glycol, 0.1-2 parts of thickener, pH adjusting agent
0.1-5 parts, 35-50 parts of water.
Further, the mass fraction of each raw material are as follows: 16-48 parts of micromolecule polypeptide, 4.75-16 parts of plant extracts, right
1.5-4 parts of hydroxy acetophenone, 3-8.5 parts of glycosyl trehalose, 0.15-0.4 parts of dipotassium glycyrrhizinate, 7-18 parts of glycerol, butanediol 8-
16 parts, 0.15-0.4 parts of Sodium Hyaluronate, 2.5-8 parts of niacinamide, 0.5-2.5 parts of cyclomethicone, poly dimethyl silicon
Oxygen alkane/0.5-2.5 parts of vinyl dimethicone cross polymer, 1.5-3 parts of hydrolecithin, carbohydrate isomer
0.5-1.2 parts, 0.5-1.2 parts of citric acid, 0.5-1.5 parts of sodium citrate, 1.5-4 parts of 1,2- hexylene glycol, thickener 0.5-1.5
Part, 1-4 parts of pH adjusting agent, 40-48 parts of water.
Further, micromolecule polypeptide is Matrixyl -4, Argireline, acetyl group tetrapeptide -5, myristoyl
At least one of pentapeptide -4.
Further, in terms of mass fraction, contain -4 2-15 parts of Matrixyl, 2-15 parts of Argireline, second
- 5 2-15 parts of acyl group tetrapeptide, -4 2-15 parts of myristoyl pentapeptide.
Further, in terms of mass fraction, contain -4 4-12 parts of Matrixyl, 4-12 parts of Argireline, second
- 5 4-12 parts of acyl group tetrapeptide, -4 4-12 parts of myristoyl pentapeptide.
Further, plant extracts is Astragalus membranacus root extract, Rhizoma Atractylodis Macrocephalae rhizome extract, windproof root extract, mother
At least one of chrysanthemum extract, silk tree bark extract, licorice root extract, purslane extract.
Further, in terms of mass fraction, contain 0.15-1.5 parts of Astragalus membranacus root extract, Rhizoma Atractylodis Macrocephalae rhizome extract
0.15-1.5 parts, windproof 0.15-1.5 parts of root extract, 0.15-1.5 parts of german chamomile flower extract, silk tree bark extract 0.15-
1.5 parts, 0.25-2.5 parts of licorice root extract, 1-10 parts of purslane extract.
Further, in terms of mass fraction, contain 0.45-1.2 parts of Astragalus membranacus root extract, Rhizoma Atractylodis Macrocephalae rhizome extract
0.45-1.2 parts, windproof 0.45-1.2 parts of root extract, 0.45-1.2 parts of german chamomile flower extract, silk tree bark extract 0.45-
1.2 parts, 0.5-2 parts of licorice root extract, 2-8 parts of purslane extract.
Further, thickener is carbomer.
Further, pH adjusting agent is triethanolamine.
The preparation method of eye mask in the present invention containing micromolecule polypeptide the following steps are included:
1) A phase is sequentially added into agitated kettle, is heated to 75-80 DEG C, stirring is completely dissolved；
2) with after 75-80 DEG C of constant temperature stirring 30min of 15HZ blender, 40 DEG C are cooled to；
3) B is added to, stirs 15min with 15HZ blender；
4) C is added to, stirs 15min with 15HZ blender；
5) D is added to, stirs 15min with 15HZ blender；
6) inspection is qualified, and discharging, sampling observation is qualified, storage；
A phase are as follows: water, parahydroxyacet-ophenone, glycosyl trehalose, dipotassium glycyrrhizinate, glycerol, butanediol, Sodium Hyaluronate, cigarette
Amide, thickener；
B phase are as follows: plant extracts, cyclomethicone, Dimethicone/Vinyl Dimethicone
Cross-linked polymer, hydrolecithin, carbohydrate isomer, citric acid, sodium citrate；
C phase are as follows: pH adjusting agent；
D phase are as follows: micromolecule polypeptide, 1,2- hexylene glycol.
The beneficial effects of the present invention are:
Matrixyl -4 is Type I collagen albumen premise sequence fragment, fine in its energy intense stimulus extracellular matrix (ECM)
The growth of cell is tieed up, so that the synthesis of I and III collagen type of stimulation and fibrin and hyaluronic acid, can significantly pierce
Swash collagen in dermal layer of the skin to generate, it is obvious particular for deep wrinkles effect.
Argireline is one of earliest and most widely used crease-resistant polypeptide, is a kind of clostridium botulinum that safety is mild
Substitute can mitigate wrinkle caused by being shunk by mimetic muscle, especially in the wrinkle of eye circumference, forehead and the corners of the mouth, such as fish in a short time
Tail line, decree line, corners of the mouth line etc..
Inhibitor of the acetyl group tetrapeptide -5 as angiotensin converting enzyme, is able to suppress capillary permeability and promotes
Eye Lymph microcirculation eliminates oedema, mitigates black eye, improves skin elasticity and smoothness.There are also inhibit collagen simultaneously
Glycosylated effect can prevent collagen aging, aggregation, mitigate eye pouch and crease-resistant effect to further reach.
Myristoyl pentapeptide -4 is a kind of signal peptide for keratin gene, can be with the keratin gene table of human activin
Up to more keratin are generated, keep the more fine length of eyelashes dense.
By using four kinds of polypeptides in combination in the present invention, reasonably combined plant extracts, moisturizer and other adjuvant systems
At eye mask, without the additives such as essence, pigment, preservative.The natural safety of micromolecule polypeptide ingredient in the present invention, easy quilt
Skin absorbs, and plant extracts of arranging in pairs or groups has more significant moisture-keeping crease-shedding effect, and it is dense to can be the more fine length of eyelashes,
Keep binocular more obvious bright, it is more charming.
Detailed description of the invention
Attached drawing 1 is skin care item preparation process flow.
Specific embodiment
Below in conjunction with embodiment, the present invention is further explained, it should be appreciated that following embodiment be merely to illustrate the present invention and
It is not used in and limits the scope of the invention.
Embodiment 1
A kind of eye mask containing micromolecule polypeptide, the raw material including following mass fraction are made: 2 parts of Matrixyl -4, second
- 82 parts of acyl group hexapeptide, 2 parts of acetyl group tetrapeptide -5, -4 2 parts of myristoyl pentapeptide, 0.5 part of parahydroxyacet-ophenone, glycosyl seaweed
Sugared 1 part, 0.05 part of dipotassium glycyrrhizinate, 5 parts of glycerol, 5 parts of butanediol, 0.05 part of Sodium Hyaluronate, 1 part of niacinamide, carbomer 0.1
Part, 0.15 part of Astragalus membranacus root extract, 0.15 part of Rhizoma Atractylodis Macrocephalae rhizome extract, windproof 0.15 part of root extract, Flos Chrysanthemi extract
0.15 part of object, 0.15 part of silk tree bark extract, 0.25 part of licorice root extract, 1 part of purslane extract, ring poly dimethyl silicon
0.15 part of oxygen alkane, 0.15 part of Dimethicone/Vinyl Dimethicone cross-linked polymer, hydrolecithin 0.2
Part, 0.15 part of carbohydrate isomer, 0.15 part of citric acid, 0.2 part of sodium citrate, 0.1 part of triethanolamine, 1,2- hexylene glycol
0.5 part, 35 parts of water.
Eye mask the preparation method comprises the following steps:
Raw material is divided into tetra- phase of A, B, C and D, in which:
A phase are as follows: water, parahydroxyacet-ophenone, glycosyl trehalose, dipotassium glycyrrhizinate, glycerol, butanediol, Sodium Hyaluronate, cigarette
Amide, carbomer；
B phase are as follows: Astragalus membranacus root extract, Rhizoma Atractylodis Macrocephalae rhizome extract, windproof root extract, german chamomile flower extract, silk tree
Bark extract, licorice root extract, purslane extract, cyclomethicone, dimethyl silicone polymer/vinyl are poly-
Dimethicone crosspolymers, hydrolecithin, carbohydrate isomer, citric acid, sodium citrate；
C phase are as follows: triethanolamine；
D phase are as follows: Matrixyl -4, Argireline, acetyl group tetrapeptide -5, myristoyl pentapeptide -4,1,2- oneself two
Alcohol.
Preparation step is as follows:
1) A phase is sequentially added into agitated kettle, is heated to 80 DEG C, stirring is completely dissolved；
2) with after 80 DEG C of constant temperature stirring 30min of 15HZ blender, 40 DEG C are cooled to；
3) B is added to, stirs 15min with 15HZ blender；
4) C is added to, stirs 15min with 15HZ blender；
5) D is added to, stirs 15min with 15HZ blender；
6) inspection is qualified, and discharging, sampling observation is qualified, storage.
Embodiment 2
A kind of eye mask containing micromolecule polypeptide, the raw material including following mass fraction are made: 15 parts of Matrixyl -4,
15 parts of Argireline, 15 parts of acetyl group tetrapeptide -5, -4 15 parts of myristoyl pentapeptide, 5 parts of parahydroxyacet-ophenone, glycosyl
10 parts of trehalose, 0.5 part of dipotassium glycyrrhizinate, 20 parts of glycerol, 20 parts of butanediol, 0.5 part of Sodium Hyaluronate, 10 parts of niacinamide, card
2 parts of wave nurse, 1.5 parts of Astragalus membranacus root extract, 1.5 parts of Rhizoma Atractylodis Macrocephalae rhizome extract, windproof 1.5 parts of root extract, Flos Chrysanthemi mention
Take 1.5 parts of object, 1.5 parts of silk tree bark extract, 2.5 parts of licorice root extract, 10 parts of purslane extract, ring poly dimethyl silicon
3 parts of oxygen alkane, 3 parts of Dimethicone/Vinyl Dimethicone cross-linked polymer, 4 parts of hydrolecithin, carbohydrate are same
1.5 parts of enantiomers, 1.5 parts of citric acid, 2 parts of sodium citrate, 5 parts of triethanolamine, 5 parts of 1,2- hexylene glycol, 50 parts of water.
Eye mask the preparation method comprises the following steps:
Raw material is divided into tetra- phase of A, B, C and D, in which:
A phase are as follows: water, parahydroxyacet-ophenone, glycosyl trehalose, dipotassium glycyrrhizinate, glycerol, butanediol, Sodium Hyaluronate, cigarette
Amide, carbomer；
B phase are as follows: Astragalus membranacus root extract, Rhizoma Atractylodis Macrocephalae rhizome extract, windproof root extract, german chamomile flower extract, silk tree
Bark extract, licorice root extract, purslane extract, cyclomethicone, dimethyl silicone polymer/vinyl are poly-
Dimethicone crosspolymers, hydrolecithin, carbohydrate isomer, citric acid, sodium citrate；
C phase are as follows: triethanolamine；
D phase are as follows: Matrixyl -4, Argireline, acetyl group tetrapeptide -5, myristoyl pentapeptide -4,1,2- oneself two
Alcohol.
Preparation step is as follows:
1) A phase is sequentially added into agitated kettle, is heated to 75 DEG C, stirring is completely dissolved；
2) with after 75 DEG C of constant temperature stirring 30min of 15HZ blender, 40 DEG C are cooled to；
3) B is added to, stirs 15min with 15HZ blender；
4) C is added to, stirs 15min with 15HZ blender；
5) D is added to, stirs 15min with 15HZ blender；
6) inspection is qualified, and discharging, sampling observation is qualified, storage.
Embodiment 3
A kind of eye mask containing micromolecule polypeptide, the raw material including following mass fraction are made: 4 parts of Matrixyl -4, second
- 84 parts of acyl group hexapeptide, 4 parts of acetyl group tetrapeptide -5, -4 4 parts of myristoyl pentapeptide, 1.5 parts of parahydroxyacet-ophenone, glycosyl seaweed
Sugared 3 parts, 0.15 part of dipotassium glycyrrhizinate, 7 parts of glycerol, 8 parts of butanediol, 0.15 part of Sodium Hyaluronate, 2.5 parts of niacinamide, carbomer
0.5 part, 0.45 part of Astragalus membranacus root extract, 0.45 part of Rhizoma Atractylodis Macrocephalae rhizome extract, windproof 0.45 part of root extract, Flos Chrysanthemi mention
Take 0.45 part of object, 0.45 part of silk tree bark extract, 0.5 part of licorice root extract, 2 parts of purslane extract, ring poly dimethyl
0.5 part of siloxanes, 0.5 part of Dimethicone/Vinyl Dimethicone cross-linked polymer, hydrolecithin 1.5
Part, 0.5 part of carbohydrate isomer, 0.5 part of citric acid, 0.5 part of sodium citrate, 1 part of triethanolamine, 1.5 parts of 1,2- hexylene glycol,
40 parts of water.
Eye mask the preparation method comprises the following steps:
Raw material is divided into tetra- phase of A, B, C and D, in which:
A phase are as follows: water, parahydroxyacet-ophenone, glycosyl trehalose, dipotassium glycyrrhizinate, glycerol, butanediol, Sodium Hyaluronate, cigarette
Amide, carbomer；
B phase are as follows: Astragalus membranacus root extract, Rhizoma Atractylodis Macrocephalae rhizome extract, windproof root extract, german chamomile flower extract, silk tree
Bark extract, licorice root extract, purslane extract, cyclomethicone, dimethyl silicone polymer/vinyl are poly-
Dimethicone crosspolymers, hydrolecithin, carbohydrate isomer, citric acid, sodium citrate；
C phase are as follows: triethanolamine；
D phase are as follows: Matrixyl -4, Argireline, acetyl group tetrapeptide -5, myristoyl pentapeptide -4,1,2- oneself two
Alcohol.
Preparation step is as follows:
1) A phase is sequentially added into agitated kettle, is heated to 80 DEG C, stirring is completely dissolved；
2) with after 75 DEG C of constant temperature stirring 30min of 15HZ blender, 40 DEG C are cooled to；
3) B is added to, stirs 15min with 15HZ blender；
4) C is added to, stirs 15min with 15HZ blender；
5) D is added to, stirs 15min with 15HZ blender；
6) inspection is qualified, and discharging, sampling observation is qualified, storage.
Embodiment 4
A kind of eye mask containing micromolecule polypeptide, the raw material including following mass fraction are made: 12 parts of Matrixyl -4,
12 parts of Argireline, 12 parts of acetyl group tetrapeptide -5, -4 12 parts of myristoyl pentapeptide, 4 parts of parahydroxyacet-ophenone, glycosyl
8.5 parts of trehalose, 0.4 part of dipotassium glycyrrhizinate, 18 parts of glycerol, 16 parts of butanediol, 0.4 part of Sodium Hyaluronate, 8 parts of niacinamide, card
1.5 parts of wave nurse, 1.2 parts of Astragalus membranacus root extract, 1.2 parts of Rhizoma Atractylodis Macrocephalae rhizome extract, windproof 1.2 parts of root extract, Flos Chrysanthemi
1.2 parts of extract, 1.2 parts of silk tree bark extract, 2 parts of licorice root extract, 8 parts of purslane extract, ring poly dimethyl silicon
2.5 parts of oxygen alkane, 2.5 parts of Dimethicone/Vinyl Dimethicone cross-linked polymer, 3 parts of hydrolecithin, sugar
1.2 parts of class isomer, 1.2 parts of citric acid, 1.5 parts of sodium citrate, 4 parts of triethanolamine, 4 parts of 1,2- hexylene glycol, 48 parts of water.
Eye mask the preparation method comprises the following steps:
Raw material is divided into tetra- phase of A, B, C and D, in which:
A phase are as follows: water, parahydroxyacet-ophenone, glycosyl trehalose, dipotassium glycyrrhizinate, glycerol, butanediol, Sodium Hyaluronate, cigarette
Amide, carbomer；
B phase are as follows: Astragalus membranacus root extract, Rhizoma Atractylodis Macrocephalae rhizome extract, windproof root extract, german chamomile flower extract, silk tree
Bark extract, licorice root extract, purslane extract, cyclomethicone, dimethyl silicone polymer/vinyl are poly-
Dimethicone crosspolymers, hydrolecithin, carbohydrate isomer, citric acid, sodium citrate；
C phase are as follows: triethanolamine；
D phase are as follows: Matrixyl -4, Argireline, acetyl group tetrapeptide -5, myristoyl pentapeptide -4,1,2- oneself two
Alcohol.
Preparation step is as follows:
1) A phase is sequentially added into agitated kettle, is heated to 80 DEG C, stirring is completely dissolved；
2) with after 80 DEG C of constant temperature stirring 30min of 15HZ blender, 40 DEG C are cooled to；
3) B is added to, stirs 15min with 15HZ blender；
4) C is added to, stirs 15min with 15HZ blender；
5) D is added to, stirs 15min with 15HZ blender；
6) inspection is qualified, and discharging, sampling observation is qualified, storage.
Embodiment 5
A kind of eye mask containing micromolecule polypeptide, the raw material including following mass fraction are made: 8 parts of Matrixyl -4, second
- 88 parts of acyl group hexapeptide, 8 parts of acetyl group tetrapeptide -5, -4 8 parts of myristoyl pentapeptide, 3 parts of parahydroxyacet-ophenone, glycosyl trehalose
6 parts, 0.3 part of dipotassium glycyrrhizinate, 12.5 parts of glycerol, 12 parts of butanediol, 0.25 part of Sodium Hyaluronate, 5.5 parts of niacinamide, carbomer
1 part, 0.8 part of Astragalus membranacus root extract, 0.8 part of Rhizoma Atractylodis Macrocephalae rhizome extract, windproof 0.8 part of root extract, german chamomile flower extract
0.8 part, 0.8 part of silk tree bark extract, 1.3 parts of licorice root extract, 6 parts of purslane extract, cyclomethicone
1.5 parts, 1.5 parts of Dimethicone/Vinyl Dimethicone cross-linked polymer, 2.3 parts of hydrolecithin, carbohydrate
0.85 part of isomer, 0.85 part of citric acid, 1 part of sodium citrate, 2.5 parts of triethanolamine, 2.3 parts of 1,2- hexylene glycol, water 45
Part.
Eye mask the preparation method comprises the following steps:
Raw material is divided into tetra- phase of A, B, C and D, in which:
A phase are as follows: water, parahydroxyacet-ophenone, glycosyl trehalose, dipotassium glycyrrhizinate, glycerol, butanediol, Sodium Hyaluronate, cigarette
Amide, carbomer；
B phase are as follows: Astragalus membranacus root extract, Rhizoma Atractylodis Macrocephalae rhizome extract, windproof root extract, german chamomile flower extract, silk tree
Bark extract, licorice root extract, purslane extract, cyclomethicone, dimethyl silicone polymer/vinyl are poly-
Dimethicone crosspolymers, hydrolecithin, carbohydrate isomer, citric acid, sodium citrate；
C phase are as follows: triethanolamine；
D phase are as follows: Matrixyl -4, Argireline, acetyl group tetrapeptide -5, myristoyl pentapeptide -4,1,2- oneself two
Alcohol.
Preparation step is as follows:
1) A phase is sequentially added into agitated kettle, is heated to 75 DEG C, stirring is completely dissolved；
2) with after 75 DEG C of constant temperature stirring 30min of 15HZ blender, 40 DEG C are cooled to；
3) B is added to, stirs 15min with 15HZ blender；
4) C is added to, stirs 15min with 15HZ blender；
5) D is added to, stirs 15min with 15HZ blender；
6) inspection is qualified, and discharging, sampling observation is qualified, storage.
Using effect
30-60 years old women is selected, eye has 50 people of subject of apparent microgroove, is divided into 5 groups, and every group of 10 people try respectively
With the eye mask in embodiment 1-5.Time on probation is 90 days, primary in night use every 5 days, after cleaning face, directly will
Eye mask is uniformly applied to eye circumference.When before proof test starting with trying out 90 days, analyzed using face skin detector tested
Person's eye same position skin condition, 50% or more microgroove reduction are denoted as effective.All subjects carry out allergy test before test,
All subjects occur without allergic phenomena.
Result on trial
Claims (10)
1. a kind of eye mask containing micromolecule polypeptide, wherein containing: micromolecule polypeptide, plant extracts, parahydroxyacet-ophenone, glycosyl
Trehalose, dipotassium glycyrrhizinate, glycerol, butanediol, Sodium Hyaluronate, niacinamide, cyclomethicone, polydimethylsiloxanes
Alkane/vinyl dimethicone cross polymer, hydrolecithin, carbohydrate isomer, citric acid, sodium citrate,
1,2- hexylene glycol, thickener, pH adjusting agent, water.
2. the eye mask according to claim 1 containing micromolecule polypeptide, it is characterised in that: the mass fraction of each raw material are as follows: small
8-60 parts of molecular polypeptide, 2-20 parts of plant extracts, 0.5-5 parts of parahydroxyacet-ophenone, 1-10 parts of glycosyl trehalose, glycyrrhizic acid two
0.05-0.5 parts of potassium, 5-20 parts of glycerol, 5-20 parts of butanediol, 0.05-0.5 parts of Sodium Hyaluronate, 1-10 parts of niacinamide, ring poly- two
0.15-3 parts of methylsiloxane, 0.15-3 parts of Dimethicone/Vinyl Dimethicone cross-linked polymer, hydrogenation
0.2-4 parts of lecithin, 0.15-1.5 parts of carbohydrate isomer, 0.15-1.5 parts of citric acid, 0.2-2 parts of sodium citrate, 1,2-
0.5-5 parts of hexylene glycol, 0.1-2 parts of thickener, 0.1-5 parts of pH adjusting agent, 35-50 parts of water.
3. the eye mask according to claim 2 containing micromolecule polypeptide, it is characterised in that: the mass fraction of each raw material are as follows: small
It is 16-48 parts of molecular polypeptide, 4.75-16 parts of plant extracts, 1.5-4 parts of parahydroxyacet-ophenone, 3-8.5 parts of glycosyl trehalose, sweet
0.15-0.4 parts of oxalic acid dipotassium, 7-18 parts of glycerol, 8-16 parts of butanediol, 0.15-0.4 parts of Sodium Hyaluronate, niacinamide 2.5-8
Part, 0.5-2.5 parts of cyclomethicone, Dimethicone/Vinyl Dimethicone cross-linked polymer
0.5-2.5 parts, 1.5-3 parts of hydrolecithin, 0.5-1.2 parts of carbohydrate isomer, 0.5-1.2 parts of citric acid, sodium citrate
0.5-1.5 parts, 1.5-4 parts of 1,2- hexylene glycol, 0.5-1.5 parts of thickener, 1-4 parts of pH adjusting agent, 40-48 parts of water.
4. described in any item eye masks containing micromolecule polypeptide according to claim 1~3, it is characterised in that: micromolecule polypeptide is
At least one of Matrixyl -4, Argireline, acetyl group tetrapeptide -5, myristoyl pentapeptide -4.
5. the eye mask according to claim 4 containing micromolecule polypeptide, it is characterised in that: in terms of mass fraction, contain palm
- 4 2-15 parts of acyl pentapeptide, 2-15 parts of Argireline, -5 2-15 parts of acetyl group tetrapeptide, -4 2-15 of myristoyl pentapeptide
Part.
6. described in any item eye masks containing micromolecule polypeptide according to claim 1~3, it is characterised in that: plant extracts is
Astragalus membranacus root extract, Rhizoma Atractylodis Macrocephalae rhizome extract, windproof root extract, german chamomile flower extract, silk tree bark extract, Radix Glycyrrhizae
At least one of root extract, purslane extract.
7. the eye mask according to claim 6 containing micromolecule polypeptide, it is characterised in that: in terms of mass fraction, contain film pod
0.15-1.5 parts of Radix Astragali root extract, 0.15-1.5 parts of Rhizoma Atractylodis Macrocephalae rhizome extract, windproof 0.15-1.5 parts of root extract, Flos Chrysanthemi
0.15-1.5 parts of extract, 0.15-1.5 parts of silk tree bark extract, 0.25-2.5 parts of licorice root extract, purslane extract
1-10 parts.
8. described in any item eye masks containing micromolecule polypeptide according to claim 1~3, it is characterised in that: thickener is card wave
Nurse.
9. described in any item eye masks containing micromolecule polypeptide according to claim 1~3, it is characterised in that: pH adjusting agent three
Ethanol amine.
10. the eye mask according to claim 1 containing micromolecule polypeptide, preparation method includes the following steps:
1) A phase is sequentially added into agitated kettle, is heated to 75-80 DEG C, stirring is completely dissolved；
2) with after 75-80 DEG C of constant temperature stirring 30min of 15HZ blender, 40 DEG C are cooled to；
3) B is added to, stirs 15min with 15HZ blender；
4) C is added to, stirs 15min with 15HZ blender；
5) D is added to, stirs 15min with 15HZ blender；
6) inspection is qualified, and discharging, sampling observation is qualified, storage；
A phase are as follows: water, parahydroxyacet-ophenone, glycosyl trehalose, dipotassium glycyrrhizinate, glycerol, butanediol, Sodium Hyaluronate, nicotinoyl
Amine, thickener；
B phase are as follows: plant extracts, cyclomethicone, Dimethicone/Vinyl Dimethicone crosslinking
Polymer, hydrolecithin, carbohydrate isomer, citric acid, sodium citrate；
C phase are as follows: pH adjusting agent；
D phase are as follows: micromolecule polypeptide, 1,2- hexylene glycol.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| CN201910502880 | 2019-06-11 | ||
| CN2019105028805 | 2019-06-11 |
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| CN110302089A true CN110302089A (en) | 2019-10-08 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201910556708.8A Pending CN110302089A (en) | 2019-06-11 | 2019-06-25 | Eye mask and preparation method thereof containing micromolecule polypeptide |
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| US11311475B2 (en) | 2019-01-02 | 2022-04-26 | The Procter And Gamble Company | Skin care compositions containing peptide compound and aphanothece sacrum exopolysaccharide extract |
| US11571378B2 (en) | 2021-01-22 | 2023-02-07 | The Procter & Gamble Company | Skin care composition and method of using the same |
| US11771637B2 (en) | 2021-01-22 | 2023-10-03 | The Procter & Gamble Company | Skin care composition and method of using the same |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US11311475B2 (en) | 2019-01-02 | 2022-04-26 | The Procter And Gamble Company | Skin care compositions containing peptide compound and aphanothece sacrum exopolysaccharide extract |
| US11571378B2 (en) | 2021-01-22 | 2023-02-07 | The Procter & Gamble Company | Skin care composition and method of using the same |
| US11771637B2 (en) | 2021-01-22 | 2023-10-03 | The Procter & Gamble Company | Skin care composition and method of using the same |
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