CN110302071A - Blue light protection cosmetic composition and preparation method thereof and the cosmetics for including the composition - Google Patents
Blue light protection cosmetic composition and preparation method thereof and the cosmetics for including the composition Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
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- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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- A61K2800/592—Mixtures of compounds complementing their respective functions
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Abstract
The invention discloses a kind of blue lights to protect cosmetic composition, each component containing following weight percents: opacifier is 0.01%~10.00%, and antioxidant is 0.01%~5.00%, and whitening agent is 0.01~10.00%, and anatrophic is 0.01%~20.00%.Blue light protection cosmetic composition can effectively resist and the injury caused by skin of maintenance blue light, safeguards skin health.The invention also discloses the preparation methods of blue light protection cosmetic composition, and the cosmetics containing the composition.
Description
Technical field
The present invention relates to cosmetic technical field, blue light protects cosmetic composition and preparation method thereof and includes the group
Close the cosmetics of object.
Background technique
As the all-round market of emerging light source technology is universal, blue light becomes the light injury of human body and the influence of Vision Health
Social hotspots.The product that blue light protecting film is influenced as effective protection blue light is applied in optical mirror slip, display, illuminating product
It is more and more extensive.
Blue light is wavelength between 400-500nm, the shortest high-energy visible light of wavelength.
Our daily contacted blue lights, 90% derives from daylight, and 10% from electronic equipment in daily life, such as day
Light lamp, mobile phone screen, computer screen, I pad screen etc..
With popularizing for smart phone, it is contemplated that 53% will be increased in the user of the year two thousand twenty smart phone, we use daily
The frequency of electronic product is also continuously increased, and the time in face of screen also constantly increases.
Under natural situation, human body is stepped up vigilance using blue light, adjusts biological rhythm.Artificial blue light (LED therapy) issues blue
Light pulse generates oxidative pressure to cure skin injury (LudgerKolbe.How much sun protection is
Needed?: Are we on the way to full-spectrum protection? Journal of
Investigative Dermatology(2012)132,1756–1757.)。
Although the blue light of appropriate dosage has certain benefit to our daily life and skin health, according in recent years
Come some research institutions studies have shown that human body is exposed to for a long time under the blue light of large dosage, can come for the health care belt of human body certain
Harm:
1) continued eye exposure under blue light, leads to visual fatigue, eye early ageing and sleep disordered.
2) since the wavelength of blue light is long, the deep enough skin of energy increases active oxygen (Dupont, E.Beyond UV
radiation:A skin under challenge,International Journal of Cosmetic Science,
2013,35,224-234.), degradation collagen and elastin laminin, damage mitochondrial DNA (Bernard F,
Godley.etc.Blue Light Induces Mitochondrial DNA Damage and Free Radical
production in Epidermal Cells.The Journal Of Biological Chemistry.Vol.280,
No.22, Issue of June 3, pp.21061-21066,2005.), weaken epidermal barrier, postpones epidermal barrier reparation
(Mitsuhiro,Denda；Shigeyoshi,Fuziwara.Visible Radiation Affects Epidermal
Permeability Barrier Recovery:Selective Effects of Red and Blue Light.Journal
Of Investigative Dermatology (2008) 128,1335-1336.), lead to hyperpigmentation, outside damaging cells
Matrix is to accelerated ageing.
Therefore, product or the invention that blue light protection can be provided for the mankind are more and more important.
Currently, occurring some blue light Protection Products for vision protection on the market, such as blue light safety goggles, anti-blue light
Screen protecting film, anti-blue light energy-saving lamp etc., but lack the cosmetics of the blue light protection for human skin protection.
Although commercially available sunscreen product has the function of protecting human bodies light injury, primarily directed to the shorter (280- of wavelength
The protection of ultraviolet light 400nm), and be willing and yet unable to help for longer wavelengths of blue light (400-500nm) protection.
In addition, commercially available sunscreen product contains a large amount of ultraviolet absorbing agent, it is most of more greasy, airtight, even
There is certain stimulation to skin, protection when unsuitable consumer is indoors or night uses electronic equipment for a long time to light.
Summary of the invention
Goal of the invention: the purpose of the invention is to make up the deficiency of existing investigative technique, a kind of blue light protection is provided
Cosmetic composition.
Technical solution: a kind of blue light protects cosmetic composition, each component containing following weight percents: opacifier is
0.01%~10.00%, antioxidant is 0.01%~5.00%, and whitening agent is 0.01~10.00%, anatrophic 0.01%
~20.00%.
Preferably, by weight percentage, the opacifier is 0.05%~5.00%, the antioxidant is
0.05%~2.50%, the whitening agent is 0.05~5.00%, and the anatrophic is 0.05%~10.00%.
Preferably, the optical wavelength range that the opacifier may filter that is 400-500nm, the opacifier is selected from methylene
In base pair-benzotriazole base tetramethyl butyl phenol, zinc oxide, titanium dioxide, melanin, borsal calcium and cerium oxide at least
It is a kind of；
Preferably, the antioxidant is selected from carnosine, tetrahydro curcumin, fullerene, tocopherol and its derivative, anti-bad
Hematic acid and its derivative, ubiquinone, glutathione, glutathione peroxidase, superoxide dismutase, resveratrol, shrimp are green
At least one of element, lutein, gallic acid, beta carotene, milk thistle extract, lycopene and procyanidine；Institute
Antioxidant is stated for preventing oxidative damage and removing free radical.
The whitening agent be selected from glycyrrhiza glabra root extract, hydrolysis conchiolin, emblic berry extract, mulberry tree (root/
Branch/leaf) extract, ascorbic acid and its derivative, 4- butyl resorcinol, hexyl resorcin, Symwhite-337, α-
Arbutin, kojic acid, tranexamic acid, diacetyl boldine, didextrose base gallate, undecylenoyl phenyl alanine, nonapeptide -1,
Yeast extract, punarnava root extract, tricholoma matsutake, ginseng extract, red algae extract, Semen Pisi sativi extract, bubble leaf
The sub- seed oil of algae extract, western Radix rumicis acetosae extract, medicine hollyhock extract, Rhizoma Polygonati Odorati extract, dark green tea bit of a bridle, peony extract, Radix Malvae sylvestris
Extract, garment or robe made of feathers grass extract, sweet mary extract, cowslip extract, veronica officinalis extract, common milfoil extract
Object, radix scutellariae root extract, Artemisia capillaris flower extract, jujube berry extract, tuckahoe extracts, Chinese herbaceous peony root extract, chrysanthemum extract,
The extraction of radix ampelopsis root, Rhizoma Atractylodis Macrocephalae root extract, shaggy-fruited dittany root extract, the bark of official magnolia bark extract, Angelica roots and bletilla striata root extract
At least one of；Whitening agent is used to inhibit the synthesis of melanin (to inhibit tyrosinase, DHICA oxidizing ferment (TRP-1), DOPA
The activity of pigment interconvertible enzyme (TRP-2) and α-MSH melanotropin), reduction melanin, inhibition and promote melanin transfer.
The anatrophic is selected from cacao seed extract, Jasmine leaf cell extract, Flos Tagetis Erectae extract, hydrolysis of pea egg
White, poly- Umbrella Yan Qiang Wei extract, retinol and its derivative, -1 copper of tripeptides, four victory peptide hexanoyls -3, acetyl group tetrapeptide -2, false friendship
For monad tunning extract, acetyl hydroxyproline, plankton extractions, rice tunning filtrate, glycerol glucose
Glycosides, tetrahydro methylpyrimidine carboxylic acid, Grifola Frondosa sporophore extract, bidens pilosa extract, salicyloyl phytosphingosine and apple
At least one of fruit seed extract.Anatrophic is for inhibiting collagen and elastin degradation and improving skin elasticity and wrinkle
Line.
Further, the blue light protection cosmetic composition in the present invention further includes by weight percentage moisturizer
0.10-20.00%, thickener 0.01-5.00%, grease 0.01-30.00%, emulsifier 0.01-10.00%, bacteriostatic agent
0.01-5.00%, surplus add water to absolutely.
Preferably, the moisturizer is selected from one of natural origin moisturizer and synthesis moisturizer or combinations thereof；
Preferably, the thickener is selected from one of natural source thickener and chemical synthesis thickener or its group
It closes；
Preferably, the grease in plant source grease, animal sources grease, petroleum source grease, Synthetic Oil one
Kind or combinations thereof；
Preferably, the emulsifier is selected from one of oil-water emulsifiers and water-in-oil emulsifier or combinations thereof；
Preferably, the bacteriostatic agent is selected from one of chemical synthesis preservative and natural source bacteriostatic agent or its group
It closes.
Preferably, the moisturizer is selected from glycerol, glycine betaine, trehalose, methyl gluceth -20, hyaluronic acid
Sodium, butanediol, dried tremella extract, propylene glycol, 1,3- propylene glycol, pungent glycol, acetyl chitosamine, dipropylene glycol, panthenol, PEG/
PPG-17/6 copolymer, algaroba berry extract, Anjidew NL50, Flos Rosae Rugosae extract, ethoxy urea, in polyglutamic acid sodium at least
It is a kind of；
Preferably, the thickener is selected from ammonium acryloyl taurate/VP copolymer, acryloyldimethyl ox sulphur
Sour ammonium/- 25 Methacrylate Crosspolymer of docosyl alcohol polyethers, Sodium Polyacrylate, hydroxy-ethyl acrylate/acryloyldimethyl
Taurate Copolymer, acrylic acid (ester) analog copolymer (sodium), polyacrylate cross-linked polymer -6, hydroxyethyl cellulose, silicon
Sour sodium magnesium lithium, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer, carbomer, Scleroglucan, hydrolysis pyrenomycetes
At least one of glue and gellan gum；
Preferably, the grease is selected from jojoba seed oil, isohexadecane, thorn A Ganshu benevolence oil, Butyrospermum parkii fruit rouge, angle
Shark alkane, lauric alcohol-caprylate/decylate, Dermol 105, horse fat, two heptanoate of neopentyl glycol, dormant oil, tridecanol are inclined
Benzenetricarboxylic acid ester, great Hua cocoa seeds of trees rouge, vaseline, olive oil, hydrogenated coco-glyceride class, paraffin, C12-15 alcohol benzoic acid
Ester, docosyl alcohol, dimethyl silicone polymer, ring five dimethyl silicone polymer, octyl polymethyl siloxane, dimethyl silicone polymer/
At least one of vinyl dimethicone cross polymer, cetostearyl alcohol, isopropyl palmitate；
Preferably, the emulsifier is selected from five stearate of Natrulon H-10, PEG-100 stearate, stearoyl lactoyl
Sodium lactate, C12-20 alkyl glucoside, Phosphoric acid monohexadecyl ester potassium, tribehenin essence PEG-20 esters, hydrolecithin, methyl
Sesquialter isostearate, PEG-20 methyl sesquistearate, stearine, PEG-75 stearate, stearoyl
Dilactic acid sodium, PEG-120 methyl dioleate, ceteth -20, stereth -20, polysorbate -20,
The smooth olive oleate of Natrulon H-10 myristinate, Plantacare 818, sorb, lauryl PEG-9 polydimethylsiloxanes ethyl are poly-
At least one of dimethyl siloxane, PEG-10 Polydimethylsiloxane；
Preferably, the bacteriostatic agent is sweet selected from potassium sorbate, sodium benzoate, dehydroactic acid sodium, Phenoxyethanol, chlorobenzene
Ether, methyl hydroxybenzoate, Nipasol, bright string coccus/radish root tunning filtrate, 1,2- pentanediol, Ammopiptanthus mongolicus lift in object
It is at least one.
The invention also discloses the preparation methods of blue light protection cosmetic composition, include the following steps:
1) grease, emulsifier are added in oily phase pot, are heated to 82-87 DEG C when stirring (10-50rpm), are sufficiently stirred
To uniform, oil mixture is obtained；
2) water, moisturizer, thickener are added in water phase pot, are heated to 82-87 DEG C when stirring (10-50rpm), sufficiently
It is stirred until homogeneous, obtains aqueous mixture；
3) by oil mixture, aqueous mixture pass sequentially through strainer valve be pumped into vacuum emulsification pot in, with revolving speed be 30~
35rpm is stirred, and is then that 2500~3200rpm carries out homogeneous extremely emulsification uniformly with revolving speed；
4) speed of agitator is down to 10~30rpm, is cooled to 45 DEG C, be separately added into opacifier, antioxidant, whitening agent,
Anatrophic and bacteriostatic agent continue to discharge after being stirred until homogeneous；
5) filling after detection is qualified to protect cosmetic composition to get blue light.
Third object of the present invention is to disclose a kind of cosmetics, and it includes above-mentioned blue lights to protect cosmetic combinations
Object, and the cosmetics are any cosmetic form.
Blue light protection cosmetic composition of the invention selects the shading that the optical wavelength range that may filter that is 400-500nm
Agent, the antioxidant that oxidative damage can be prevented and remove free radical, inhibition and reduction melanin and the beauty for controlling melanin metabolism
White dose and can inhibit collagen and elastin degradation and improve the anatrophic of skin elasticity and wrinkle, and by by they into
The scientific and reasonable combination of row, play it is synergistic, preferably resist and the injury caused by skin of maintenance blue light, maintenance skin are strong
The effect of health.
Using the cosmetics for including the cosmetic composition can effectively reduce skin splash caused by blue light generation,
Reduce blue light caused by Skin Cell active o content increase, reduce blue light caused by wrinkle of skin increase and can be significant
Skin elasticity is improved, and then reduces skin aging caused by blue light, safeguards the health of skin.
Detailed description of the invention
Colour patterns comparison diagram caused by Fig. 1 embodiment 4 and 1,2,5 pair of blue light of comparative example；
Cell activity oxygen caused by Fig. 2 embodiment 4 and 1,3 pair of blue light of comparative example changes comparison diagram；
Wrinkle caused by Fig. 3 embodiment 4 and 1,4 pair of blue light of comparative example changes effect contrast figure；
Skin elasticity caused by Fig. 4 embodiment 4 and 1,4 pair of blue light of comparative example changes comparison diagram.
Specific embodiment
The present invention will be described below by way of specific embodiments, but the present invention is not limited thereto.In following embodiments
The experimental method is unless otherwise specified conventional method；The reagent and material unless otherwise specified can be from business
Approach obtains, the scope of the patents that following example is not intended to limit the invention, all equivalence enforcements without departing from carried out by the present invention
Or change, it is intended to be limited solely by the scope of this patent.
Preparation method in the present invention, includes the following steps:
1) grease, emulsifier are added in oily phase pot, are heated to 82-87 DEG C when stirring (10-50rpm), are sufficiently stirred
To uniform, oil mixture is obtained；
2) water, moisturizer, thickener are added in water phase pot, are heated to 82-87 DEG C when stirring (10-50rpm), sufficiently
It is stirred until homogeneous, obtains aqueous mixture；
3) by oil mixture, aqueous mixture pass sequentially through strainer valve be pumped into vacuum emulsification pot in, with revolving speed be 30~
35rpm is stirred, and is then that 2500~3200rpm carries out homogeneous extremely emulsification uniformly with revolving speed；
4) speed of agitator is down to 10~30rpm, is cooled to 45 DEG C, be separately added into opacifier, antioxidant, whitening agent,
Anatrophic and bacteriostatic agent continue to discharge after being stirred until homogeneous；
5) filling after detection is qualified to protect cosmetic composition to get blue light.
Embodiment 1: blue light protects cosmetic composition (toner)
The blue light protection cosmetic composition of the present embodiment is composed of the following components:
Water 77.05%；Thickener: hydrolysis Scleroglucan 0.15%；Moisturizer: glycerol 20.00%；Opacifier: zinc oxide
0.10%；Antioxidant: superoxide dismutase 0.05%；Whitening agent: punarnava root extract 0.05%；Anatrophic: hydrolysis
Pea protein 0.05%, plankton extractions 0.05%；Bacteriostatic agent: 1,2- pentanediol 2.50%.
Embodiment 2: blue light protects cosmetic composition (Essence)
The blue light protection cosmetic composition of the present embodiment is composed of the following components:
Water 64.60%；Thickener: xanthan gum 0.15%；Moisturizer: 1,3- propylene glycol 10.00%；Emulsifier: polyglycereol-
10 myristinates 1.50%；Grease: great Hua cocoa seeds of trees rouge 0.50%；Opacifier: titanium dioxide 5.00%；Antioxidant:
Tocopherol acetate 2.50%；Whitening agent: peony extract 3.50%, Vitamin C sodium phosphate 1.50%；Anatrophic: poly- Umbrella rock
Qiang Wei extract 1.50%, Jasmine leaf cell extract 3.00%, Flos Tagetis Erectae extract 5.00%, acetyl group tetrapeptide -2
0.50%；Bacteriostatic agent: Phenoxyethanol: 0.60%, methyl hydroxybenzoate: 0.15%.
Embodiment 3: blue light protects cosmetic composition (w/o type lotion)
The blue light protection cosmetic composition of the present embodiment is composed of the following components:
1) oily phase: emulsifier: lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone 2.50%, PEG-10
Dimethyl silicone polymer 1.50%；Grease: ring five dimethyl silicone polymer 10.00%, cetostearyl alcohol 2.50%, the poly- first of octyl
Radical siloxane 4.00%, jojoba seed oil 2.50%, isohexadecane 5.00% pierce A Ganshu benevolence oil 2.00%, Butyrospermum parkii fruit
Rouge 1.50%, saualane 3.00%, lauric alcohol-caprylate/decylate 5.00%, Dermol 105 8.00%；
2) water phase: water 24.90%；Moisturizer: Sodium Hyaluronate 0.10%, glycine betaine 1.50%, dipropylene glycol 8.00%,
Panthenol 2.00%, PEG/PPG-17/6 copolymer 1 .50%, algaroba berry extract 2.00%, Anjidew NL50 2.50%；
3) opacifier: methylene bis-benzotriazolyl tetramethyl butyl phenol 0.50%；Antioxidant: glutathione
0.10%；Whitening agent: Symwhite-337 1.00%, alpha-arbutin 0.50%；Anatrophic: tetrahydro methylpyrimidine carboxylic acid
0.20%, rice tunning filtrate 2.00%, glycosylglycerol 2.00%, Grifola Frondosa sporophore extract 1.50%, three leaves
Beggarticks extract 1.00%, salicyloyl phytosphingosine 0.50%；Bacteriostatic agent: Phenoxyethanol 0.55%, Chlorphenesin
0.15%.
4 blue light of embodiment protects cosmetic composition (O/W type lotion)
The blue light protection cosmetic composition of the present embodiment is composed of the following components:
1) oily phase: emulsifier: C12-20 alkyl glucoside 3.00%, Natrulon H-10 myristinate 1.50%；Grease:
Butyrospermum parkii fruit rouge 1.00%, saualane 4.00%, dimethyl silicone polymer 2.00%；
2) water phase: water 72.10%；Moisturizer: butanediol 8.00%；Thickener: xanthan gum 0.20%；
3) opacifier: titanium dioxide 2.50%；Antioxidant: tocopherol acetate 0.30%, carnosine 0.20%；Whitening
Agent: glycyrrhiza glabra root extract 2.50%；Anatrophic: cacao seed extract 2.00%；Bacteriostatic agent: Phenoxyethanol 0.70%.
Comparative example 1-5 blue light protects cosmetic composition (O/W type lotion)
Comparative example 1-5 is identical as the basic components of embodiment 4, the difference is that being free of opacifier, antioxidant, whitening
Agent and anatrophic, or containing only one of which, specifically it is shown in Table 1.
The formula composition of 1 comparative example 1-5 of table
Embodiment 1-4 is prepared into corresponding blue light according to above-mentioned preparation method respectively and protects cosmetics, comparative example 1-5 system
Standby obtained photoprotection cosmetics carry out Performance Evaluation, and assessment content includes:
1, color spot quantity is tested
Utilize the situation of change of VISIA skin analysis system testing color spot in skin after blue light illumination.
Subject: totally 10 people, male 4 people, 6 people of female, the age 23-48 years old, average age 32.10 years old；
Light source: LED blue light 475nm (3mW/cm2Continue 30min)；
Subject: being randomly divided into 2 groups by test method, prepared by embodiment 4, comparative example 1, comparative example 2 and comparative example 5
Lotion difference equivalent (half face of 1.5g/) is applied to two one side of something of subject or so on the face, after absorbing and parching within 5 minutes, with above-mentioned LED
Blue light illumination subject face 30 minutes, the color of VISIA skin analysis system testing subject face was used in repetition after continuing 28 days
Spot quantity.
2, cell activity oxygen content is tested
It is shone using the dyeing of CellROX fluorescence intensity and Volocity image software quantitative analysis mankind's horn cell through blue light
Penetrate the active o content of front and back.
Light source: LED blue light 415nm (3mW/cm2Continue 18min)；
Cell: normal human subject horn cell；
Test method: by normal human subject horn cell respectively with the water containing 1.00% embodiment 4, comparative example 1 and comparative example 3
Solution processing for 24 hours, then uses the LED blue light (3mW/cm of 415nm2) prolonged exposure 18min, it is further continued for using at above-mentioned aqueous solution
Reason for 24 hours, then proceedes to the LED blue light (3mW/cm with 415nm2) prolonged exposure 18min, schemed after fluorescent staining with Volocity
As software quantitative analysis fluorecyte quantity.
3, wrinkle of skin and flexibility test
Subject is analyzed using DermaTOP image analyzer, CK skin elasticity tester uses blue light protection makeup
Wrinkle of skin and Flexible change before and after product composition.
Subject: totally 12 people, male 4 people, 8 people of female, the age 23-48 years old, average age 32.33 years old；
Light source: screen blue light (mobile phone, computer, tablet computer)；
Subject: being randomly divided into 3 groups by test method, the lotion for respectively preparing embodiment 4, comparative example 1 and comparative example 4
Equivalent (2mg/cm) is applied to two one side of something of subject or so on the face, once in the morning and once at night, is used continuously 8 weeks, during using product,
Want centre plane to screen blue light (mobile phone, computer, tablet computer) 4h.Respectively before use, the 56th day with DermaTOP image point
Analyzer, CK skin elasticity tester analyze the wrinkle of skin and Flexible change situation of subject's face.
The result of color spot quantity test is as shown in Figure 1, it is seen that half face of subject's smearing embodiment 4 relatively smearing comparative example 1,
Comparative example 2, comparative example 5 partly the visible color spot quantity of naked eyes substantially reduces on the face, illustrate that the blue light protects cosmetic composition energy
Effectively reduce the generation of skin splash caused by blue light.
The result of cell activity oxygen content test is as shown in Figure 2, it is seen that the cell activity through embodiment 4, the processing of comparative example 3
Oxygen is significantly reduced compared with the cell activity oxygen content that comparative example 1 is handled, and illustrates that blue light protection cosmetic composition can effectively subtract
Cell activity oxygen caused by few blue light.
The result of wrinkle of skin and flexibility test is as shown in Figure 3 and Figure 4, and half face that subject smears embodiment 4 is relatively smeared
Comparative example 1, comparative example 4 half wrinkle substantially reduce, elasticity significantly increases.Furthermore 75% subject thinks to smear
Half face skin of embodiment 4 is more sliding tender, illustrates that blue light protection cosmetic composition can effectively reduce skin caused by blue light and decline
Always.
Several preferred embodiments of the invention have shown and described in above description, but as previously described, it should be understood that the present invention
Be not limited to forms disclosed herein, should not be regarded as an exclusion of other examples, and can be used for various other combinations,
Modification and environment, and the above teachings or related fields of technology or knowledge can be passed through within that scope of the inventive concept describe herein
It is modified.And changes and modifications made by those skilled in the art do not depart from the spirit and scope of the present invention, then it all should be in this hair
In the protection scope of bright appended claims.
Claims (8)
1. a kind of blue light protects cosmetic composition, which is characterized in that each component containing following weight percents: opacifier is
0.01%~10.00%, antioxidant is 0.01%~5.00%, and whitening agent is 0.01~10.00%, anatrophic 0.01%
~20.00%.
2. protecting cosmetic composition according to blue light described in right 1, which is characterized in that by weight percentage, the shading
Agent is 0.05%~5.00%, and the antioxidant is 0.05%~2.50%, and the whitening agent is 0.05~5.00%, described
Anatrophic is 0.05%~10.00%.
3. blue light according to claim 1 protects cosmetic composition, which is characterized in that the light that the opacifier may filter that
Wave wave-length coverage is 400-500nm, and the opacifier is selected from methylene bis-benzotriazolyl tetramethyl butyl phenol, zinc oxide, two
At least one of titanium oxide, melanin, borsal calcium and cerium oxide；
The antioxidant is selected from carnosine, tetrahydro curcumin, fullerene, tocopherol and its derivative, ascorbic acid and its derivative
Object, glutathione, glutathione peroxidase, superoxide dismutase, resveratrol, astaxanthin, lutein, does not have ubiquinone
At least one of gallate-based, beta carotene, milk thistle extract, lycopene and procyanidine；
The whitening agent be selected from glycyrrhiza glabra root extract, hydrolysis conchiolin, emblic berry extract, mulberry tree (root/branch/
Leaf) extract, ascorbic acid and its derivative, 4- butyl resorcinol, hexyl resorcin, Symwhite-337, α-bear
Fruit glycosides, kojic acid, tranexamic acid, diacetyl boldine, didextrose base gallate, undecylenoyl phenyl alanine, nonapeptide -1, ferment
Female extract, punarnava root extract, tricholoma matsutake, ginseng extract, red algae extract, Semen Pisi sativi extract, yellow tang
The sub- seed oil of extract, western Radix rumicis acetosae extract, medicine hollyhock extract, Rhizoma Polygonati Odorati extract, dark green tea bit of a bridle, peony extract, Radix Malvae sylvestris mention
Object, garment or robe made of feathers grass extract, sweet mary extract, cowslip extract, veronica officinalis extract, common milfoil is taken to extract
Object, radix scutellariae root extract, Artemisia capillaris flower extract, jujube berry extract, tuckahoe extracts, Chinese herbaceous peony root extract, chrysanthemum extract,
The extraction of radix ampelopsis root, Rhizoma Atractylodis Macrocephalae root extract, shaggy-fruited dittany root extract, the bark of official magnolia bark extract, Angelica roots and bletilla striata root extract
At least one of；
The anatrophic be selected from cacao seed extract, Jasmine leaf cell extract, Flos Tagetis Erectae extract, hydrolysis of pea albumen,
Poly- Umbrella Yan Qiang Wei extract, retinol and its derivative, -1 copper of tripeptides, four victory peptide hexanoyls -3, acetyl group tetrapeptide -2, false alternately list
Born of the same parents' bacterium tunning extract, acetyl hydroxyproline, plankton extractions, rice tunning filtrate, glycosylglycerol, four
Hydrogen methylpyrimidine carboxylic acid, Grifola Frondosa sporophore extract, bidens pilosa extract, salicyloyl phytosphingosine and Apple Seeds mention
Take at least one of object.
4. blue light according to any one of claim 1-3 protects cosmetic composition, which is characterized in that with weight percent
Than meter, moisturizer 0.10-20.00%, thickener 0.01-5.00%, grease 0.01-30.00%, emulsifier 0.01-
10.00%, bacteriostatic agent 0.01-5.00%, surplus add water to absolutely.
5. blue light according to claim 4 protects cosmetic composition, which is characterized in that the moisturizer is selected from natural next
One of source moisturizer and synthesis moisturizer or combinations thereof；
The thickener is selected from one of natural source thickener and chemical synthesis thickener or combinations thereof；
The grease is selected from one of plant source grease, animal sources grease, petroleum source grease, Synthetic Oil or combinations thereof；
The emulsifier is selected from one of oil-water emulsifiers and water-in-oil emulsifier or combinations thereof；
The bacteriostatic agent is selected from one of chemical synthesis preservative and natural source bacteriostatic agent or combinations thereof.
6. blue light according to claim 5 protects cosmetic composition, which is characterized in that the moisturizer be selected from glycerol,
Glycine betaine, trehalose, methyl gluceth -20, Sodium Hyaluronate, butanediol, dried tremella extract, propylene glycol, 1,3- the third two
Alcohol, pungent glycol, acetyl chitosamine, dipropylene glycol, panthenol, PEG/PPG-17/6 copolymer, algaroba berry extract, Anjidew NL50, rose
At least one of rare flower extract, ethoxy urea, polyglutamic acid sodium；
It is poly- that the thickener is selected from ammonium acryloyl taurate/VP copolymer, ammonium acryloyldime-thyltaurate/docosyl alcohol
- 25 Methacrylate Crosspolymer of ether, Sodium Polyacrylate, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymerization
Object, acrylic acid (ester) analog copolymer (sodium), polyacrylate cross-linked polymer -6, hydroxyethyl cellulose, sodium metasilicate magnesium lithium, propylene
In sour (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer, carbomer, Scleroglucan, hydrolysis Scleroglucan and gellan gum
At least one；
The grease is selected from jojoba seed oil, isohexadecane, thorn A Ganshu benevolence oil, Butyrospermum parkii fruit rouge, saualane, lauric alcohol-
Caprylate/decylate, Dermol 105, horse fat, two heptanoate of neopentyl glycol, dormant oil, tridecanol trimellitate, great Hua
Cocoa seeds of trees rouge, vaseline, olive oil, hydrogenated coco-glyceride class, paraffin, C12-15 alcohol benzoic ether, docosyl alcohol, poly- two
Methylsiloxane, ring five dimethyl silicone polymer, octyl polymethyl siloxane, dimethyl silicone polymer/vinylpolydimethyl
At least one of Dimethicone Crosspolymer, cetostearyl alcohol, isopropyl palmitate；
The emulsifier is selected from five stearate of Natrulon H-10, PEG-100 stearate, stearoyl dilactic acid sodium, C12-20
Alkyl glucoside, Phosphoric acid monohexadecyl ester potassium, tribehenin essence PEG-20 esters, hydrolecithin, methyl sesquialter isostearic acid
Ester, PEG-20 methyl sesquistearate, stearine, PEG-75 stearate, stearoyl dilactic acid sodium,
PEG-120 methyl dioleate, ceteth -20, stereth -20, polysorbate -20, Natrulon H-10 meat
The smooth olive oleate of myristate, Plantacare 818, sorb, lauryl PEG-9 polydimethylsiloxanes ethyl polydimethylsiloxanes
At least one of alkane, PEG-10 Polydimethylsiloxane；
The bacteriostatic agent is selected from potassium sorbate, sodium benzoate, dehydroactic acid sodium, Phenoxyethanol, Chlorphenesin, methyl hydroxybenzoate, hydroxyl
Phenylpropyl alcohol ester, bright string coccus/radish root tunning filtrate, 1,2- pentanediol, Ammopiptanthus mongolicus lift at least one of object.
7. the preparation method of the protection cosmetic composition of blue light described in a kind of any one of claim 4-6, which is characterized in that
Include the following steps:
1) grease, emulsifier are added in oily phase pot, are heated to 82-87 DEG C when stirring (10-50rpm), be stirred well to
It is even, obtain oil mixture；
2) water, moisturizer, thickener are added in water phase pot, are heated to 82-87 DEG C when stirring (10-50rpm), are sufficiently stirred
To uniform, aqueous mixture is obtained；
3) oil mixture, aqueous mixture are passed sequentially through strainer valve to be pumped into vacuum emulsification pot, with revolving speed for 30~35rpm
It is stirred, is then that 2500~3200rpm carries out homogeneous extremely emulsification with revolving speed；
4) speed of agitator is down to 10~30rpm, is cooled to 45 DEG C, be separately added into opacifier, antioxidant, whitening agent, anti-ageing
Agent and bacteriostatic agent continue to discharge after being stirred until homogeneous；
5) filling after detection is qualified to protect cosmetic composition to get blue light.
8. a kind of cosmetics, include cosmetic composition of any of claims 1-6, the cosmetics are anyization
Cosmetic form.
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|---|---|---|---|
| CN201910528459.1A CN110302071A (en) | 2019-06-18 | 2019-06-18 | Blue light protection cosmetic composition and preparation method thereof and the cosmetics for including the composition |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910528459.1A CN110302071A (en) | 2019-06-18 | 2019-06-18 | Blue light protection cosmetic composition and preparation method thereof and the cosmetics for including the composition |
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|---|---|
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ID=68076707
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|---|---|---|---|
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Application publication date: 20191008 |
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