CN110269832A - A kind of anti-aging Essence of the fungus extract containing root nodule and preparation method thereof - Google Patents

A kind of anti-aging Essence of the fungus extract containing root nodule and preparation method thereof Download PDF

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Publication number
CN110269832A
CN110269832A CN201811298358.1A CN201811298358A CN110269832A CN 110269832 A CN110269832 A CN 110269832A CN 201811298358 A CN201811298358 A CN 201811298358A CN 110269832 A CN110269832 A CN 110269832A
Authority
CN
China
Prior art keywords
skin
root nodule
aging
fungus extract
essence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201811298358.1A
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Chinese (zh)
Inventor
夏黎明
施惠喆
黄文羽
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangzhou Jnumeso Biotechnology Inc
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Guangzhou Jnumeso Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangzhou Jnumeso Biotechnology Inc filed Critical Guangzhou Jnumeso Biotechnology Inc
Priority to CN201811298358.1A priority Critical patent/CN110269832A/en
Publication of CN110269832A publication Critical patent/CN110269832A/en
Withdrawn legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

Abstract

The invention discloses a kind of anti-wrinkle containing root nodule fungus extract, anti-aging cosmetics and preparation method thereof, it is related to cosmetics preparation field, in particular to a kind of Essence and preparation method thereof with removing wrinkle and resisting aging effect always.The features such as the present invention provides a kind of existing preferable moisturizings, moisturizing effect, and have the facial treatment essence liquid of senile-resistant efficacy, and the facial treatment essence liquid has skin sense soft and smooth property, easily sprawl easy absorption.Facial treatment essence liquid of the invention, can significantly improve the elasticity of skin, and anti-aging effects are good.

Description

A kind of anti-aging Essence of the fungus extract containing root nodule and preparation method thereof
Technical field
The present invention relates to cosmetics preparation field, in particular to a kind of Essence and its system with removing wrinkle and resisting aging effect always Preparation Method.
Background technique
In recent years, with the development of the society, the raising of living standards of the people, people want the quality and performance of cosmetics Ask also higher and higher, cosmetics are no longer limited to the mixture of industrial chemicals product, need combine skin physiology, psychology, The multi-disciplinary theoretical and research achievement such as pharmacology, thus meeting the needs of people are to cosmetics in different level.
Body nutrient balance is critically important to the skin for maintaining health, perhaps skin cannot be made to youthen, but ignore this Point will but greatly speed up skin aging.Skin aging is the intrinsic physiological mechanism of human senility and extraneous exposing to the weather, environment dirt The coefficient result of the damage such as dye.Reasonable nutrition can partially inhibit physiological aging, but be difficult to protect skin not by the external world The influence of environment.The presenility excessively of skin could only be inhibited by supplement nutrient in due course.
In the numerous extraneous factors for causing skin aging, skin photoage caused by ultraviolet radioactive is most important reason One of, long-term ultraviolet light irradiation can cause the peroxidating of Skin Cell, increase the free-radical contents in skin, and in skin Middle generation lipid peroxide, and the collagen in lipid peroxide and skin acts on, and skin can be made to follow the string, and freely Base can promote elastomer to crosslink and polymerize again, and can cause elastin laminin and collagen degradation, to make skin keratin Excessively, so that skin is become coarse, relaxation, the aging phenomena such as wrinkle occur.Therefore, the ultraviolet protection of skin is the weight of anti-aging Measure is wanted, the attention to light problem of aging is based on, sunscreen cosmetic has become an important field in everyday skincare. However, in skin care item add ultraviolet absorbing agent be only from outer protection skin from UV-induced skin lesion must Want means.Due to current sunscreen product preparation technique and consumer's use aspect the problem of, to by merely using sun-proof Product reach to skin absolutely ultraviolet protection be it is very difficult, therefore, in skin care item add natural biological it is thin Born of the same parents protect additive, to improve the immune protection of skin itself, promote skin elasticity cell to generate, especially by reduction Free radical reduces the peroxidation of Skin Cell inner lipid ingredient, is then particularly important.
For many years the study found that beta glucan is the activator of macrophage, in terms of immunology viewpoint, what is be activated is huge Phagocyte can induce immune connection grade amplification, as a result generate cytokinin, epithelical cell growth factor (ECGF), angiogenic growth Thus the factor (AF) and interferon can stimulate Skin Cell active, promote cell Proliferation metabolism, help skin rejuvenation, reduce skin Skin wrinkle generates, delay skin aging.
Summary of the invention
For the demand of current Cosmetic Market, the present invention provides a kind of existing preferable moisturizings, moisturizing effect, and have There is the features such as facial treatment essence liquid of senile-resistant efficacy, the facial treatment essence liquid has skin sense soft and smooth property, easily sprawls easy absorption.This The facial treatment essence liquid of invention, can significantly improve the elasticity of skin, and anti-aging effects are good.
The purpose of the present invention is what is be achieved through the following technical solutions:
A kind of anti-aging Essence of the fungus extract containing root nodule, which is characterized in that the total weight based on Essence, the essence Liquid includes the ingredient of following weight proportion:
Further, the root nodule fungus extract is prepared through special control purification technique with good water The beta glucan of dissolubility just has highly-water-soluble and fairly good skin sense without carboxy methylation.
Further, the moisturizer be propylene glycol, glycerol, dipropylene glycol, methyl propanediol, 1,2- pentanediol, 1,3- Butanediol, Sodium Hyaluronate, two kinds or more of combination in tremella polysaccharides.
Further, the emollient is reed fragrant plant glue, reed fragrant plant oil, PPG-10 methyl ether, polyglycereol;
Preferably, moisturizer is the combination of glycerol, methyl propanediol, pentanediol and Sodium Hyaluronate.
Further, the skin conditioning agent be licorice, Mel extract, purslane extract, yeast extract, At least one of rose flower extract or several combinations;
It is another object of the present invention to what is be achieved through the following technical solutions:
A kind of preparation method with the removing wrinkle and resisting aging Essence of effect always, comprising the following steps:
1) water of formula ratio is added in a kettle, begins to warm up, while opening stirring;
2) moisturizer of formula ratio, emollient are added in the reaction kettle, are heated to 85 DEG C, keep each material sufficiently molten Solution is cooled to 45 DEG C after keeping the temperature half an hour;
3) skin conditioning agent, preservative, colorant for sequentially adding formula ratio, stir evenly, and be down to room temperature;
4) it discharges after detection is qualified, then carries out filling, be then packed and stored.
The beneficial effects of the present invention are:
1, the stoste texture with senile-resistant efficacy of the invention is plentiful, natural no stimulation, has good replenishing water and preserving moisture Effect, while a variety of anti-aging strategies are used, it can not only be used for the skincare product to delay senescence after aging occurs, but also as prevention The daily skincare product that aging generates, anti-aging effects become apparent from.
2, the present invention is needed by the moisturizing for combining polysaccharide moisturizer, skin conditioning agent etc. to meet skin different level It asks, while skin being helped preferably to enter in benign cycle, adjust the hydration of skin, not only reached instant moisturizing effect, but also can be deep Enter skin and help long-acting water holding, makes skin that water profit state be presented;It can promote cellular respiration simultaneously, promote the aerobic rate of cell, promote Cell metabolism reduces stress reaction;And can effectively clear free radical and active oxygen, impaired skin is repaired, protection flesh is reached The effect of skin.Each component is reasonably combined, synergistic effect, safe and stable, can be used for moisturizing, provide the cosmetics of energy for skin In.
3, the stoste for having effects that removing wrinkle and resisting aging is old of the invention, the root nodule fungus extract contained have stronger film forming Ability and hygroscopicity make cuticula keep certain water content, to reach moisturizing and reparation by adjusting the percutaneous loss of water The effect of the barrier function of skin.
Ability and hygroscopicity make cuticula keep certain water content, to reach guarantor by adjusting the percutaneous loss of water The effect of barrier function that is wet and repairing skin.
The features such as anti-aging Essence of the present invention has skin sense soft and smooth property, easily sprawls easy absorption.Of the invention Facial treatment essence liquid, can significantly improve the elasticity of skin, and anti-aging effects are good.
Detailed description of the invention
Fig. 1 is to add the anti-ageing Essence of different root nodule fungus extracts to skin elasticity improvement schematic diagram.
Specific embodiment
Below with reference to embodiment, the present invention is described in further detail, and embodiments of the present invention are not limited thereto.
Embodiment 1
A kind of anti-aging Essence is made: root nodule fungus extract 2%, glycerol of the component of following mass percent meter 3%, methyl propanediol 4%, tremella polysaccharides 0.3%, reed fragrant plant glue 2%, polyglycereol 2%, licorice 0.2%, purslane mentions Take object 3%, preservative 1% and excess water;The total percentage composition of above-mentioned each component is 100%.
Embodiment 2
A kind of anti-aging Essence is made: root nodule fungus extract 4%, glycerol of the component of following mass percent meter 6%, 1,3-BDO 6%, reed fragrant plant glue 2%, tremella polysaccharides 0.2%, PPG-10 methyl ether 2%, licorice 0.2%, yeast extract 6%, preservative 0.8% and excess water;The total percentage composition of above-mentioned each component is 100%.
Embodiment 3
A kind of anti-aging Essence is made of the component of following mass percent meter: root nodule fungus extract 6%, and 1,2- penta Glycol 3%, methyl propanediol 4%, dipropylene glycol 4%, Sodium Hyaluronate 0.2%, reed fragrant plant oil 2%, polyglycereol 2%, Radix Glycyrrhizae mentions Take object 0.2%, rose flower extract 3%, preservative 1% and excess water;The total percentage composition of above-mentioned each component is 100%.
Methyl propanediol 4%, 1,2- pentanediol 1%, Sodium Hyaluronate 0.3%, reed fragrant plant glue 2%, polyglycereol 2%, honey Extract 1%, purslane extract 2%, preservative 0.6% and excess water;The total percentage composition of above-mentioned each component is 100%.
Embodiment 5
The present embodiment is the testing result of above-described embodiment:
Research uses suction method, and with constant negative pressure mode, i.e. test probe applies negative pressure in skin surface and sucks skin Probe aperture, skin deformation is restored after negative pressure disappears, skin deformation with negative pressure and time change can by emit in tester light and The device for receiving light measures, which can reflect that skin is inhaled into depth, and skin stretch length can be obtained in this way and change over time Curve graph, indicate skin maximum tension amount with Uf, the stretching of dermoreaction when Ue is indicated on constant negative pressure to skin 0.1 second Amount, Ur indicate that no negative pressure skin amount of recovery after 0.1 second, Uv=Uf-Ue viscoelasticity part, Ua indicate that cancel negative pressure connects to next Continuous test is again plus the amount of recovery of negative pressure skin, R2=Ua/Uf, R2 are the parameter of a reflection skin elasticity, the more big then skin of R2 value Skin elasticity is better, better closer to 1 elasticity.
Test number is 40 people, is divided into 4 groups, every group of 10 people, test period is 28 days, using skin elasticity as test index.
Test method is before smearing sample, and subject cleans face using identical mild detergent, in subject face Left and right sides symmetric position selectes about 5 × 5cm2About 0.5g implementation is smeared on the left of face as Experimental Area in the region of size The anti-aging Essence of example, smears the reference substance of equivalent on the right side of face, and reference substance does not add rhizobium compared with embodiment and mentions Object is taken, frequency of use is that once in the morning and once at night, continuous use daily avoids outdoor from being exposed to the sun.
Before using anti-aging Essence of the invention, in test zone Reviscometer RV600 skin test Instrument detects each experiment position elasticity R2 value, is repeated 5 times respectively, obtains average value;
It is detected respectively again after smearing 7,14,21,28 days at these positions, each detection zone respectively detects 5 hypoelasticity R2 value, and find out 5 R2 average values of the period.
40 subjects measure subject's face using reference substance and after each embodiment 28 days, by skin elasticity tester Skin elasticity variation at mark point using preceding with 7,14,21,28 days after use is as shown in Figure 1, embodiment 1, real as shown in Figure 1 It applies example 2, embodiment 3,4 skin elasticity of embodiment and the trend improved is presented relative to reference substance, 4 groups of skin elasticities of embodiment are opposite It improves significant.
Embodiments of the present invention are not restricted to the described embodiments, other any without departing from Spirit Essence of the invention With the changes, modifications, substitutions, combinations, simplifications done under principle, equivalent substitute mode should be, be included in of the invention Within protection scope.

Claims (6)

1. a kind of anti-aging Essence of fungus extract containing root nodule, which is characterized in that the Essence includes following weight proportion Ingredient:
Wherein root nodule fungus extract be from root nodule bacteria culture fluid through special purification technique it is isolated have good aqueous solubility Beta glucan, design feature is that three spirals being polymerized by D-Glucose.
2. the anti-aging Essence of the fungus extract according to claim 1 containing root nodule, it is characterised in that: the moisturizer is By following two or more than at being grouped as: propylene glycol, glycerol, dipropylene glycol, methyl propanediol, 1,2- pentanediol, 1,3- fourth Glycol, Sodium Hyaluronate, tremella polysaccharides.
3. the anti-aging Essence of the fungus extract according to claim 1 containing root nodule, it is characterised in that: the emollient is The combination of one or more of reed fragrant plant glue, reed fragrant plant oil, polyglycereol, PPG-10 methyl ether, and be water solubility.
4. the anti-aging Essence of the fungus extract according to claim 1 containing root nodule, it is characterised in that: the skin condition Agent is one or both of licorice, yeast extract, Mel extract, purslane extract, rose flower extract Above combination.
5. the anti-aging Essence of the fungus extract according to claim 1 containing root nodule, it is characterised in that: the preservative is The compound of paraben esters, Phenoxyethanol and Sensiva SC50.(paraben esters are preferably methyl p-hydroxybenzoate, to hydroxyl Yl benzoic acid ethyl ester, propylparaben, n -butyl p -hydroxybenzoate and p-Hydroxybenzoic acid isobutyl ester, more preferably Methyl p-hydroxybenzoate).
6. a kind of anti-aging essence liquid and preparation method thereof of fungus extract containing root nodule as described in Claims 1 to 5, feature exist In: the preparation method comprises the following steps:
1) water of formula ratio is added in a kettle, begins to warm up, while opening stirring;
2) moisturizer of formula ratio, emollient are added in the reaction kettle, are heated to 85 DEG C, dissolve each material sufficiently, protected 45 DEG C are cooled to after warm half an hour;
3) skin conditioning agent, the preservative for sequentially adding formula ratio, stir evenly, and be down to room temperature;
4) it discharges after detection is qualified, then carries out filling, be then packed and stored.
CN201811298358.1A 2018-10-25 2018-10-25 A kind of anti-aging Essence of the fungus extract containing root nodule and preparation method thereof Withdrawn CN110269832A (en)

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Application Number Priority Date Filing Date Title
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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150174033A1 (en) * 2012-06-15 2015-06-25 Syrnrise AG Cosmetic Compositions Comprising Hyaluronan Biosynthesis Promoting Agents
CN105250184A (en) * 2015-11-18 2016-01-20 关美玲 Whitening anti-aging essence liquid and preparation method thereof
US20160228351A1 (en) * 2013-09-22 2016-08-11 Cutech Srl Extracts of halimione portulacoides and their application
CN106038416A (en) * 2016-07-19 2016-10-26 欧标(广州)化妆品有限公司 Cool and refreshing composition as well as medicament and cosmetic containing cool and refreshing composition
CN107802540A (en) * 2017-11-29 2018-03-16 广东芭薇生物科技股份有限公司 A kind of anti-apolexis composition and its application

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150174033A1 (en) * 2012-06-15 2015-06-25 Syrnrise AG Cosmetic Compositions Comprising Hyaluronan Biosynthesis Promoting Agents
US20160228351A1 (en) * 2013-09-22 2016-08-11 Cutech Srl Extracts of halimione portulacoides and their application
CN105250184A (en) * 2015-11-18 2016-01-20 关美玲 Whitening anti-aging essence liquid and preparation method thereof
CN106038416A (en) * 2016-07-19 2016-10-26 欧标(广州)化妆品有限公司 Cool and refreshing composition as well as medicament and cosmetic containing cool and refreshing composition
CN107802540A (en) * 2017-11-29 2018-03-16 广东芭薇生物科技股份有限公司 A kind of anti-apolexis composition and its application

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Application publication date: 20190924

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