CN110237140A - A kind of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition and preparation method thereof - Google Patents
A kind of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of Eradicates necrotic tissue and promoting muscle growing Chinese medicine compositions and preparation method thereof comprising following raw materials: the coptis, radix scutellariae, Cortex Phellodendri, Radix Notoginseng, safflower, borneol, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), elder, the rhizome of davallia, radix paeoniae rubra, minium, wild aconite root, sesame oil.The invention has the benefit that Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition of the present invention is using natural plants and traditional Chinese medicine perfect combination, antibacterial Eradicates corruption is made it have to draw out the pus, prevent the effect of skin bacteria breed, it can accelerate the metabolism of skin, contain skin division growth-promoting factors, promotes dry and cracked healing skin.Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition of the present invention has good therapeutic effect to the various wounds such as bedsore, burn, scald.Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition quality of the present invention is fine and smooth, smell is salubrious, does not add essence, pigment and preservative, after use, can quickly be absorbed by the skin, guarantee the dry and comfortable cleaning of skin.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition and preparation method thereof.
Background technique
For skin as first of physiology defence line of human body and maximum organ, the moment participates in the functional activity of body, dimension
Hold the unity of opposites of body and natural environment.In daily life, accidentally injury is extremely incident thing, skin to skin
When injured and inflammation infection, skin ulcer can be generated by dealing with improperly.
Various wounds such as burn and scald, wound, sore class (such as bedsore, Venous Ulcers) and hand postoperative incision do not conform to disease
Disease is clinically relatively common, and not only incidence is high, but also sick and wounded degree is multifarious, and traumatogenic reason is also varied, currently,
The means of the above-mentioned illness of clinical treatment have very much, but curative effect is different.The drug for being used to treat above-mentioned illness in western medicine therapy is used
It is exactly antibiotic, but effects of antibiotics is uncertain, completely ineffective if selecting medicine not suit the medicine to the illness, the side effect of antibiotic is compared
Greatly；Chinese medical and herbal therapy is another preferable approach for treating above-mentioned illness, and this kind of Chinese medicine is also many currently on the market, such as
Very famous Yunnan Baiyao and civil some burning hot plaster etc. play mitigate the wounded's slight illness to a certain extent, auxiliary
The effect for helping wound to heal, existing Chinese medicine drug majority scheme is from following ancient prescription, though some flavour of a drug are more, but drug effect
Difference, some then pharmacological property conflicts, brings side effect.
The reason of leading to wound long disunion, has very much, and wherein the age of patient is excessive, and tissue repairing ability's difference is easy to lead
The long disunion of mouth of causing injury, the systemic disease such as diabetes, chronic liver disease, panatatrophia are also possible to that wound is caused not to be cured
It closes, it is daily improper diet to also result in the long disunion of wound.In addition, wound surface defect of skin is excessive, and wound infection, wound
Inside there is foreign matter, debridement is not thorough, and the factors such as hemotoncus, inadequate drainage, suture mouth skin Poor fitness in wound, are to cause to hurt
The reason of mouth long disunion.
Summary of the invention
The object of the present invention is to provide one kind have antibacterial Eradicates is rotten, accelerate skin metabolism, prevent skin bacteria breed,
Promote the Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition of skin healing.
A kind of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition, the raw material including following weight parts: 1-10 parts of the coptis, 1-10 parts of radix scutellariae,
1-10 parts of Cortex Phellodendri, 1-5 parts of Radix Notoginseng, 1-5 parts of safflower, 1-5 parts of borneol, 1-3 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), 1-3 parts of elder, bone
1-15 parts of broken benefit, 1-15 parts of radix paeoniae rubra, 1-15 parts of minium, 1-5 parts of wild aconite root, 10-20 parts of sesame oil.
Further, the Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition, the raw material including following weight parts: 4-8 parts of the coptis, radix scutellariae
4-8 parts, 4-8 parts of Cortex Phellodendri, 2-4 parts of Radix Notoginseng, 2-4 parts of safflower, 2-4 parts of borneol, 1-2 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), elder 1-
2 parts, 5-10 parts of the rhizome of davallia, 5-10 parts of radix paeoniae rubra, 5-10 parts of minium, 2-3 parts of wild aconite root, 12-18 parts of sesame oil.
Further, the Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition, the raw material including following weight parts: 5 parts of the coptis, 6 parts of radix scutellariae,
6 parts of Cortex Phellodendri, 3 parts of Radix Notoginseng, 3 parts of safflower, 3 parts of borneol, 2 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), 2 parts of elder, 8 parts of the rhizome of davallia, 8 parts of radix paeoniae rubra, camphor tree
Red 8 parts, 3 parts of wild aconite root, 15 parts of sesame oil.
The function that the coptis has antibacterial, inhibits influenza virus and hepatitis B in Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition of the present invention
Effect, radix scutellariae have heat-clearing and damp-drying drug, removing toxic substances, anti-inflammatory effect, the immunity of body also can be improved；Cortex Phellodendri has heat-clearing and damp-drying drug, purging intense heat
The effect of except steaming；Radix Notoginseng has effects that dissipating stasis and stanching bleeding；Safflower has effects that blood circulation, removing blood stasis and acesodyne；Borneol has suppression
The effect that bacterium, anti-inflammatory, promotion effective component are absorbed by organisms；Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) has effects that dispelling wind and eliminating dampness, anti-inflammatory analgesic；It connects
Bone wood has effects that dredging the channel, activating microcirculation and removing stasis medicinal, analgesic；The rhizome of davallia has effects that continues and hinders pain relieving；Radix paeoniae rubra has heat-clearing cool
The effect of blood, removing blood stasis and acesodyne；Minium, wild aconite root have effects that scattered blood and dissolving stasis, swelling and pain relieving；In Eradicates necrotic tissue and promoting muscle growing of the present invention
Drug composition plays using Radix Notoginseng, safflower, elder, minium, wild aconite root as monarch drug in a prescription and accelerates the metabolism of skin, promotes skin
The effect of healing；Radix scutellariae, the coptis, Cortex Phellodendri are ministerial drug, play the effect of preventing skin bacteria breed；Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), the rhizome of davallia,
Radix paeoniae rubra is adjuvant, plays the role of anti-inflammatory analgesic；Borneol is the quick absorption that adjutant can promote effective component in drug.
The preparation method of the Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition, comprising the following steps:
(1) Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract is prepared；
(2) remaining each raw material for removing Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) is crushed, is filtered, then mixed with Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract
It stirs evenly, obtains mixed-powder；
(3) dry mixed powder, sterilization, the mixed-powder after sterilizing is added in sesame oil, and is mixed evenly, is obtained
The Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition.
Further, in step (1), the preparation method of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract, comprising the following steps:
A, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) is sliced, is then impregnated with clear water, wait impregnate finish, drain away the water it is spare；
B, it is sliced with heat oil pot frying Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), finishes, drain to frying, carry out frying；
C, parched medicinal material is ground into powder, obtains the Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract.
Further, it in step a, is impregnated with clear water are as follows: impregnate Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) with clear water, and replace one every 4-6h
Secondary water impregnates three.
Further, in step b, the oil is vegetable oil；Frying oil temperatures are 100-150 DEG C, frying at this temperature
Time is 10-15min；The temperature of the frying is 60-80 DEG C, and the frying time at this temperature is 3-6min.
Further, in step c, the fineness of gained Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract is 100-150 mesh.
Further, in step (2), the fineness of gained mixed-powder is 100-150 mesh.
Further, in step (3), the temperature of the drying is 60-80 DEG C, and the dry time is 8-10h；It is described to kill
Bacterium is microwave disinfection.
Each raw material is ground into fine powder, facilitated in this way by the production technology of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition of the present invention
Effective component in raw material is absorbed by organisms.
Coptis herbaceos perennial belongs to Ranunculaceae Coptis, has effects that heat-clearing and damp-drying drug, purging fire for removing toxin, be commonly used to
Damp and hot feeling of fullness is treated, acid regurgitation, dysphoria and insomnia, hot eyes, toothache etc. are vomitted.Additionally there is antibacterial, antitumor and anti-arrhythmia
Pharmacological activity, influenza virus and hepatitis B etc. can be inhibited.
Radix scutellariae is Lamiaceae plant radix scutellariae, has the effect of heat-clearing and damp-drying drug, removing toxic substances, cures mainly warm heat disease, the infection of the upper respiratory tract, lung
Heat cough, pneumonia, hemoptysis etc..Furthermore radix scutellariae has the function of antiviral, can inhibit influenza virus, hepatitis type B virus；Have
Anti-inflammatory effect can improve the immunity of body.
Cortex Phellodendri is the dry bark of rutaceae wampee, bitter, cold in nature, the function with heat-clearing and damp-drying drug, purging intense heat, except steaming
Effect is commonly used to the symptoms such as treatment damp-heat dysentery, leukorrhagia pruritus vulvae, hectic fever due to yin labor heat, night sweat.
Radix Notoginseng is Umbellales Araliaceae, sweet in flavor, slight bitter, warm-natured, has effects that dissipating stasis and stanching bleeding, detumescence ding-tong.This
Outer Radix Notoginseng has anti-inflammatory, the effect of liver protection, and the notoginsenoside in Radix Notoginseng has antineoplastic action.
Safflower category dicotyledon, composite family, it is acrid flavour, warm-natured, have effects that blood circulation, removing blood stasis and acesodyne, is commonly used to control
Treat dysmenorrhea, lochia, traumatic injury etc..
Borneol also known as piece brain, kapur etc. are that the resin of Spore density kapur and the extraction of volatile oil processed goods obtain
The crystallization obtained, is near pure d-Bomeol.Its smell faint scent, taste are refrigerant.Borneol have the function of it is antibacterial, anti-inflammatory,
Mucous membrane and subcutaneous tissue easily absorb, very light applied to stimulation of the part to sensory nerve, and have analgesic and mild anti-corrosion to make
With can be used for neuralgia.
Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) is derived from Yunnan, is civil wide-spread Sichuan and the bruise used, the anodyne cured the wound.For buttercup
The root tuber of section's plant aconitum brachypodum etc., it is bitter, warm-natured, have effects that dispelling wind and eliminating dampness, anti-inflammatory analgesic, is commonly used to treatment bruise damage
The symptoms such as wound, fracture, treating rheumatic ostealgia, toothache, venomous snake bite.Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) mainly contains three Alkaloid monoester type biologies
Alkali, diester-type alkaloids and lipo-alkaloids, lipo-alkaloids have the bioactivity such as analgesia, anti-inflammatory, with diester-type alkaloids
It compares, toxicity is smaller.
Sambucus machaka is the very high medicinal material of medical value simply, has great effect at medicinal aspect.It can dredge
The effects of degrading the channel, activating microcirculation and removing stasis medicinal, analgesic, clinically it is mainly used for rheumatic arthralgia, injuries from falls as well, oedema and difficult urination
Deng.
Davallia Polypodiaceae, Davallia have effects that The strong bone of kidney tonifying, continues and hinders pain relieving, are commonly used to treatment kidney deficiency
The symptoms such as pain in the loins, Hiccough and deaf, tooth mobility, injured bone.
Radix paeoniae rubra is the dry root of ranunculaceae plant radix paeoniae rubra or river radix paeoniae rubra, and bitter, cold nature have clearing heat and cooling blood, and the scattered stasis of blood is stopped
The effect of pain, is commonly used to treatment thermal man's ying blood, febrile virulent maculae, hematemesis and epistaxis, red eye, swell pain, liver-depressed hypochondrium pain, amenorrhea and algomenorrhea, addiction lump in the abdomen
Abdominal pain, injury from falling down, the symptoms such as carbuncle swells sore.
Minium is called red powder, Zhu Fen, lead powder used in cosmetics, acrid flavour, slightly cold, has effects that scattered blood and dissolving stasis, detumescence ding-tong, is commonly used to control
Treat malignant sore swollen drug.
Wild aconite root has effects that dispelling wind and eliminating dampness, warming channel and expelling cold, swelling and pain relieving, is commonly used to treatment wind-cold-dampness arthralgia, arthritis
Bitterly, trusted subordinate's crymodynia, cold hernia such as are had a pain at the symptoms.
The invention has the benefit that Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition of the present invention uses natural plants and traditional Chinese medicine
Perfect combination makes it have antibacterial Eradicates corruption and draws out the pus, prevents the effect of skin bacteria breed, can accelerate the metabolism of skin, accumulate
Growth-promoting factors are divided containing skin, promote dry and cracked healing skin.Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition of the present invention to bedsore, burn,
The various wounds such as scald have good therapeutic effect.
Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition quality of the present invention is fine and smooth, smell is salubrious, does not add essence, pigment and anti-corrosion
Agent after use, can be quickly absorbed by the skin, and guarantee the dry and comfortable cleaning of skin.
Specific embodiment
Embodiment 1
A kind of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition, the raw material including following weight parts: coptis 1kg, radix scutellariae 1kg, Cortex Phellodendri 1kg,
Radix Notoginseng 1kg, safflower 1kg, borneol 1kg, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 1kg, elder 1kg, rhizome of davallia 1kg, radix paeoniae rubra 1kg, minium 1kg, system
Radix aconiti agrestis 1kg, sesame oil 10kg.
The preparation method of the Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition, comprising the following steps:
(1) Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract is prepared；
(2) remaining each raw material for removing Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) is crushed, is filtered, then mixed with Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract
It stirs evenly, obtains mixed-powder；
(3) dry mixed powder, sterilization, the mixed-powder after sterilizing is added in sesame oil, and is mixed evenly, is obtained
The Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition.
Embodiment 2
A kind of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition, the raw material including following weight parts: coptis 4kg, radix scutellariae 4kg, Cortex Phellodendri 4kg,
Radix Notoginseng 2kg, safflower 2kg, borneol 2kg, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 1kg, elder 1kg, rhizome of davallia 5kg, radix paeoniae rubra 5kg, minium 5kg, system
Radix aconiti agrestis 2kg, sesame oil 12kg.
The preparation method of the Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition, comprising the following steps:
(1) Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract is prepared；Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) is sliced, then with clear water impregnate, every 4h more
A water is changed, is impregnated three, is finished, drain away the water spare wait impregnate, the heat oil pot frying Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) for being 100 DEG C with oil temperature
It is sliced 10min, finishes, drains to frying, parched medicinal material is ground into powder, obtained by frying 3min under conditions of temperature is 60 DEG C
Fineness is the Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract of 100 mesh；
(2) remaining each raw material for removing Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) is crushed, is filtered, then mixed with Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract
It stirs evenly, obtains the mixed-powder that fineness is 100 mesh；
(3) dry mixed powder 8h, again microwave disinfection under conditions of temperature is 60 DEG C, by the mixed-powder after sterilizing
It is added in sesame oil, and is mixed evenly, obtain the Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition.
Embodiment 3
A kind of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition, the raw material including following weight parts: coptis 5kg, radix scutellariae 6kg, Cortex Phellodendri 6kg,
Radix Notoginseng 3kg, safflower 3kg, borneol 3kg, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 2kg, elder 2kg, rhizome of davallia 8kg, radix paeoniae rubra 8kg, minium 8kg, system
Radix aconiti agrestis 3kg, sesame oil 15kg.
The preparation method of the Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition, comprising the following steps:
(1) Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract is prepared；Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) is sliced, then with clear water impregnate, every 5h more
A water is changed, is impregnated three, is finished, drain away the water spare wait impregnate, the heat oil pot frying Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) for being 110 DEG C with oil temperature
It is sliced 11min, finishes, drains to frying, parched medicinal material is ground into powder, obtained by frying 4min under conditions of temperature is 65 DEG C
Fineness is the Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract of 110 mesh；
(2) remaining each raw material for removing Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) is crushed, is filtered, then mixed with Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract
It stirs evenly, obtains the mixed-powder that fineness is 110 mesh；
(3) dry mixed powder 9h, again microwave disinfection under conditions of temperature is 65 DEG C, by the mixed-powder after sterilizing
It is added in sesame oil, and is mixed evenly, obtain the Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition.
Embodiment 4
A kind of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition, the raw material including following weight parts: coptis 8kg, radix scutellariae 8kg, Cortex Phellodendri 8kg,
Radix Notoginseng 4kg, safflower 4kg, borneol 4kg, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 2kg, elder 2kg, rhizome of davallia 10kg, radix paeoniae rubra 10kg, minium 10kg,
Wild aconite root 3kg, sesame oil 18kg.
The preparation method of the Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition, comprising the following steps:
(1) Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract is prepared；Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) is sliced, then with clear water impregnate, every 5h more
A water is changed, is impregnated three, is finished, drain away the water spare wait impregnate, the heat oil pot frying Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) for being 130 DEG C with oil temperature
It is sliced 13min, finishes, drains to frying, parched medicinal material is ground into powder, obtained by frying 3min under conditions of temperature is 75 DEG C
Fineness is the Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract of 130 mesh；
(2) remaining each raw material for removing Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) is crushed, is filtered, then mixed with Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract
It stirs evenly, obtains the mixed-powder that fineness is 130 mesh；
(3) dry mixed powder 8h, again microwave disinfection under conditions of temperature is 75 DEG C, by the mixed-powder after sterilizing
It is added in sesame oil, and is mixed evenly, obtain the Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition.
Embodiment 5
A kind of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition, the raw material including following weight parts: coptis 10kg, radix scutellariae 10kg, Cortex Phellodendri
10kg, Radix Notoginseng 5kg, safflower 5kg, borneol 5kg, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 3kg, elder 3kg, rhizome of davallia 15kg, radix paeoniae rubra 15kg, minium
15kg, wild aconite root 5kg, sesame oil 20kg.
The preparation method of the Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition, comprising the following steps:
(1) Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract is prepared；Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) is sliced, then with clear water impregnate, every 6h more
A water is changed, is impregnated three, is finished, drain away the water spare wait impregnate, the heat oil pot frying Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) for being 150 DEG C with oil temperature
It is sliced 15min, finishes, drains to frying, parched medicinal material is ground into powder, obtained by frying 6min under conditions of temperature is 80 DEG C
Fineness is the Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract of 150 mesh；
(2) remaining each raw material for removing Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) is crushed, is filtered, then mixed with Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract
It stirs evenly, obtains the mixed-powder that fineness is 150 mesh；
(3) dry mixed powder 10h, again microwave disinfection under conditions of temperature is 80 DEG C, by the mixed powder after sterilizing
End is added in sesame oil, and is mixed evenly, and obtains the Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition.
Comparative example 1: Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition is prepared according to the method for embodiment 3, difference is only that the Chinese traditional medicine composition
Raw material safflower is not added in object.
Comparative example 2: Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition is prepared according to the method for embodiment 3, difference is only that the Chinese traditional medicine composition
Raw material Cortex Phellodendri is not added in object.
Comparative example 3: Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition is prepared according to the method for embodiment 3, difference is only that the Chinese traditional medicine composition
Raw material Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) is not added in object.
Comparative example 4: Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition is prepared according to the method for embodiment 3, difference is only that the Chinese traditional medicine composition
The parts by weight of institute's fragrance oil are 5g in object.
Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition bacteriostasis property research of the present invention:
Experiment equipment:
1, in 9 generations, were cultivated in Escherichia coli (8099)；Candida albicans (ATCCI0231) cultivated for 9 generations；Staphylococcus aureus
(ATCC6538), cultivated for 9 generations；It is provided by Chinese Culture Collection Center.
2, ordinary nutrient agar culture medium, sabouraud's agar are provided by Beijing road and bridge technology Co., Ltd.
3,0.03mol/L phosphate buffer solution (PBS).
4, carrier: filter paper (2.0cm × 3.0cm), sterile measuring pipette, constant incubator etc..
Two, sample treatment
It weighs 5g Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition of the present invention to be added in 50ml sterile water dilution bottle, oscillation mixes, and puts
Enter in 70 DEG C of water-baths, taken out after 30min, obtains sample dilution mixed liquor；
The 5g resistance wound antibacterial cream of maintenance is weighed to be added in 50ml sterile water dilution bottle, oscillation mixes, it is put into 70 DEG C of water-baths,
It is taken out after 30min, obtains comparative example dilution mixed liquor.
Three, test method
According to GB15979-2002 " Disposable Sanitary Accessory sanitary standard " appendix C 4 and " disinfection technology standard "
2002 editions progress.
By strain by being diluted to certain density bacteria suspension with phosphate buffer solution, use is sterile after culture medium culture
3 kinds of bacteria suspensions are coated on lawn made of nutrient agar respectively by cotton swab, are then taken Taoist scripture sterilizing filter paper piece, are uniformly dipped respectively
Sample dilutes mixed liquor and comparative example dilutes mixed liquor, then is attached on lawn made of different bacteria suspensions respectively, is 20 in temperature
Under conditions of DEG C ± 1 DEG C, cultivate 2min, 5min, 10min, 20min, detect Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition of the present invention and
The resistance wound antibacterial cream of maintenance is to Escherichia coli (8099), Candida albicans (ATCCI0231), staphylococcus aureus (ATCC6538)
Bacteriostasis rate so in triplicate average, experimental result is as shown in table 1:
Table 1
As it can be seen from table 1 Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition of the present invention is in 20min to Escherichia coli, white
Candida albicans, staphylococcus aureus all have good bactericidal effect, and bactericidal property is better than the sterilization of the resistance wound antibacterial cream of maintenance
Performance reaches 70.75% to the sterilizing rate of Escherichia coli；71.76% is reached to the sterilizing rate of Candida albicans, to golden yellow Portugal
The sterilizing rate of grape coccus reaches 70.28%.
Inspection to Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition bacteriostasis property stability of the present invention:
By Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition of the present invention temperature be 37 DEG C -40 DEG C, the condition of relative humidity >=75%
Under, sample is taken after saving 90 days, then according to the above method to Escherichia coli (8099), Candida albicans (ATCCI0231) is golden yellow
The fungistatic effect of staphylococcus (ATCC6538) is studied, and bacteriostasis rate is as shown in table 2:
Table 2
It can be obtained through table 2, Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition of the present invention is 37 DEG C -40 DEG C in temperature, relative humidity >=
After handling under conditions of 75%, bactericidal property is not destroyed substantially, still keeps good bactericidal property.It is real to prepare bedsore animal
It tests:
Using SD rat, every angel its ischemic 2h in such a way that magnetic sheet is oppressed, Reperfu- sion 0.5h, continuous 5 circulations, and
Continuous action 4 days, rat back bedsore model is prepared, screening is randomly divided into 5 groups, is applied respectively with modeling successful rat 100
It smears described in the Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition of the present invention of equivalent (coating thin layer in wound), comparative example 1-4
Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition, daily coating twice, check after two weeks, the wound healing rate of rat.
Experimental result is as shown in table 4:
Table 4
The present invention is not limited to above-mentioned preferred forms, anyone can show that other are various under the inspiration of the present invention
The product of form, however, make any variation in its details, it is all that there is technical solution identical or similar to the present application,
It is within the scope of the present invention.
Claims (10)
1. a kind of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition, which is characterized in that the raw material including following weight parts: 1-10 parts of the coptis, radix scutellariae
1-10 parts, 1-10 parts of Cortex Phellodendri, 1-5 parts of Radix Notoginseng, 1-5 parts of safflower, 1-5 parts of borneol, 1-3 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), elder
1-3 parts, 1-15 parts of the rhizome of davallia, 1-15 parts of radix paeoniae rubra, 1-15 parts of minium, 1-5 parts of wild aconite root, 10-20 parts of sesame oil.
2. a kind of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition according to claim 1, which is characterized in that the original including following weight parts
Material: 4-8 parts of the coptis, 4-8 parts of radix scutellariae, 4-8 parts of Cortex Phellodendri, 2-4 parts of Radix Notoginseng, 2-4 parts of safflower, 2-4 parts of borneol, upper one of snow
1-2 parts of wormwood artemisia, 1-2 parts of elder, 5-10 parts of the rhizome of davallia, 5-10 parts of radix paeoniae rubra, 5-10 parts of minium, 2-3 parts of wild aconite root, sesame oil
12-18 parts.
3. a kind of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition according to claim 1, which is characterized in that the original including following weight parts
Material: 5 parts of the coptis, 6 parts of radix scutellariae, 6 parts of Cortex Phellodendri, 3 parts of Radix Notoginseng, 3 parts of safflower, 3 parts of borneol, 2 parts of Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), 2 parts of elder, bone
Broken benefit 8 parts, 8 parts of radix paeoniae rubra, 8 parts of minium, 3 parts of wild aconite root, 15 parts of sesame oil.
4. the preparation method of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition described in one of claim 1-3, which is characterized in that including following step
It is rapid:
(1) Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract is prepared；
(2) remaining each raw material for removing Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) is crushed, is filtered, then be mixed with Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract
Uniformly, mixed-powder is obtained；
(3) dry mixed powder, sterilization, the mixed-powder after sterilizing is added in sesame oil, and is mixed evenly, and is obtained described
Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition.
5. the preparation method of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition according to claim 4, which is characterized in that in step (1), on snow
The preparation method of Herba Achilleae extract, comprising the following steps:
A, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) is sliced, is then impregnated with clear water, wait impregnate finish, drain away the water it is spare；
B, it is sliced with heat oil pot frying Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), finishes, drain to frying, carry out frying；
C, parched medicinal material is ground into powder, obtains the Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) extract.
6. the preparation method of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition according to claim 5, which is characterized in that in step a, use clear water
It impregnates are as follows: impregnate Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) with clear water, and replace a water every 4-6h, impregnate three.
7. the preparation method of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition according to claim 5, which is characterized in that in step b, the oil
For vegetable oil；Frying oil temperatures are 100-150 DEG C, and the frying time at this temperature is 10-15min；The temperature of the frying
It is 60-80 DEG C, the frying time at this temperature is 3-6min.
8. the preparation method of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition according to claim 5, which is characterized in that in step c, gained snow
The fineness of aconite extract is 100-150 mesh.
9. the preparation method of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition according to claim 4, which is characterized in that in step (2), gained
The fineness of mixed-powder is 100-150 mesh.
10. the preparation method of Eradicates necrotic tissue and promoting muscle growing Chinese medicine composition according to claim 4, which is characterized in that in step (3), institute
Stating dry temperature is 60-80 DEG C, and the dry time is 8-10h；The sterilization is microwave disinfection.
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| CN110638976A (en) * | 2019-10-29 | 2020-01-03 | 陈启显 | Foot ointment for treating diabetic foot and preparation method thereof |
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