CN105125769A - Ointment for treating burns and scalds and preparation method - Google Patents
Ointment for treating burns and scalds and preparation method Download PDFInfo
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- CN105125769A CN105125769A CN201510610086.4A CN201510610086A CN105125769A CN 105125769 A CN105125769 A CN 105125769A CN 201510610086 A CN201510610086 A CN 201510610086A CN 105125769 A CN105125769 A CN 105125769A
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses an ointment for treating burns and scalds. The ointment is mainly prepared from the following bulk pharmaceutical chemicals in parts by weight: 9-14 parts of leaves of purpleflower holly, 7-13 parts of cantonese ampelopsis, 8-14 parts of semen plantaginis, 10-15 parts of Berberis dasystachya Maxim., 7-16 parts of marsh marigold, 9-15 parts of herba elsholtziae ciliatae, 8-16 parts of Rubia yunnanensis, 6-14 parts of shrubby breynia, 9-13 parts of white-flowered agapetes, 8-12 parts of herba polygalae japonicae, 7-12 parts of gypsum, 10-16 parts of bushy knotweed leaves, 8-13 parts of Achnatherum inebrians, 10-13 parts of lotus petiole, 8-15 parts of common andrographis herb and 9-12 parts of ottelia alismoides. The ointment is obtained based on years of clinical practice, has the efficiency of invigorating the circulation of blood, diminishing swelling, and regenerating tissue to heal sore, and is remarkable in curative effect.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of ointment and method for making for the treatment of burn and scald.
Background technology
Burn and scald is common unexpected injury in life, boiling water, roll medicated porridge, deep fat, heat steam burn and scald be the thing that often can occur.Burn and scald by the degree of depth, is generally divided into three degree: 1. once burn and scald: only injure epidermal area, injured skin rubefaction, swelling, feels pain smartly, but anhydrous bubble out existing.2. two degree of burn and scald: injure skin corium, local is red and swollen, heating, and hurt like hell, has obvious blister.3. three degree of burn and scald: full thickness skin fat, bone and the muscle comprised below skin is all subject to imitative evil, and skin is burned black, downright bad, at this moment pain is inviolent on the contrary, because many nerves are also damaged all together.
Publication No. CN101884657A(application number 201010243130.X) Chinese patent literature disclose a kind of medicine for the treatment of burn and scald.The medication effect solving existing treatment burn and scald is not significant especially problem.This medicine is prepared by the following method, is burnt by Cornu Naemorhedi and grinds into powder into powder, grinds into powder into powder after Herba Cirsii drying, and Field Thistle Herb and Cornu Naemorhedi powder mix with the part by weight of 0.8-1.1:1.8-2.2, stir.Publication No. CN104147272A(application number 201410458210.5) Chinese patent literature disclose a kind of burn and scald medicine, its component proportion is: Herba veronicastri villosuli 5-15 part, Hibisci Mutabilis 8-15 part, Folium Aloe 3-10 part, Spica Prunellae 5-10 part, Radix Paeoniae Rubra 6-10 part, Rhizoma Impatienis Textori 15-20 part, Corium elephatis 5-15 part, Borneolum Syntheticum 15-20 part, Margarita powder 10-20 part.Publication No. CN104784333A(application number 201410026706.5) Chinese patent literature disclose one and can promote that empyrosis wound surface heals as early as possible, prevent wound surface from infecting, prevent and reduce the ointment that cicatrix generates.Its raw material components and weight proportion are: Flos Lonicerae 80-120, Cortex Phellodendri 30-90, Rhizoma Polygoni Cuspidati 30-90, little Ilicis Purpureae 30-90, Radix Arnebiae (Radix Lithospermi) 80-120, Radix Et Rhizoma Rhei 70-100, Radix Rehmanniae 80-120, Radix Sanguisorbae 70-100, Scolopendra 70-100, LUBIANHUANG 30-90, Rhizoma Coptidis 30-90, Spora Lygodii 30-90, Oleum Sesami 2000-3000.
The ointment being used for the treatment of scald in the market has much, but curative effect differs, and the suitability is wide not, therefore should strengthen research in this respect, strives for obtaining a kind of Be very effective, instant effect, not easily stays the Chinese medicine formula of scar.
Summary of the invention
For the problem of prior art, the object of this invention is to provide ointment and the method for making of the wide treatment burn and scald of a kind of Be very effective, the use safety suitability.
Technical scheme of the present invention is:
Treat an ointment for burn and scald, be prepared from primarily of following bulk drugs, be mass parts: Ilex purpurea Hassk.[I.chinensis Sims 9-14; Radix Ampelopsis Cantoniensis 7-13; Semen Plantaginis 8-14; Cortex berberidis dasystachyae 10-15; Kincup 7-16; Herba Elsholtziae Ciliatae 9-15; Radix Rubiae Yunnanensis 8-16; Folium et cacumen Breyniae Fruticosae 6-14; Radix Agapetis Mannii 9-13; Herba Polygalae Japonicae 8-12; Gypsum Fibrosum 7-12; Folium Polygoni Cuspidati 10-16; Herba oxytropis glabrae 8-13; Petiolus nelumbinis 10-13; Herba Andrographis 8-15; Herba Otteliae Alismoidis 9-12.
Preferred version is, Ilex purpurea Hassk.[I.chinensis Sims 10-13; Radix Ampelopsis Cantoniensis 9-11; Semen Plantaginis 10-12; Cortex berberidis dasystachyae 11-14; Kincup 9-14; Herba Elsholtziae Ciliatae 11-13; Radix Rubiae Yunnanensis 10-14; Folium et cacumen Breyniae Fruticosae 8-12; Radix Agapetis Mannii 10-12; Herba Polygalae Japonicae 9-11; Gypsum Fibrosum 9-10; Folium Polygoni Cuspidati 12-14; Herba oxytropis glabrae 9-12; Petiolus nelumbinis 11-12; Herba Andrographis 10-13; Herba Otteliae Alismoidis 10-11.
More preferably, Ilex purpurea Hassk.[I.chinensis Sims 11.5; Radix Ampelopsis Cantoniensis 10; Semen Plantaginis 11; Cortex berberidis dasystachyae 12.5; Kincup 11.5; Herba Elsholtziae Ciliatae 12; Radix Rubiae Yunnanensis 12; Folium et cacumen Breyniae Fruticosae 10; Radix Agapetis Mannii 11; Herba Polygalae Japonicae 10; Gypsum Fibrosum 9.5; Folium Polygoni Cuspidati 13; Herba oxytropis glabrae 10.5; Petiolus nelumbinis 11.5; Herba Andrographis 11.5; Herba Otteliae Alismoidis 10.5.
Described a kind of preparation method for the treatment of the ointment of burn and scald, step is as follows:
(1) get Ilex purpurea Hassk.[I.chinensis Sims, Folium et cacumen Breyniae Fruticosae, Folium Polygoni Cuspidati and Herba Andrographis and clean shredding, be placed in container, do not have crude drug 1cm to soak 12-22 minute (preferably: soak 14-20 minute with vinegar; Be more preferably: soak 17 minutes), take out, put into frying pan, slow fire stir-fries to surperficial zoom, drenches and mixes thoroughly into yellow wine, and taking-up cools;
(2) get Semen Plantaginis remove impurity to clean, add the saline soak of concentration 70%, take out and be placed in frying pan, moderate heat stir-fries to there being fragrance to overflow, and taking-up is pulverized, and cools;
(3) get Gypsum Fibrosum roguing, smash, be placed in refractory container, intense fire is calcined to and is popular in, taking-up cools, and is ground into coarse powder, adds candy sugar powder mixing (mass ratio of Gypsum Fibrosum powder and candy sugar powder is 4:1), the micro-stir-fry of little fire, takes out, pulverized 150 mesh sieves together with step (1) (2) made crude drug;
(4) get Radix Ampelopsis Cantoniensis, Cortex berberidis dasystachyae, Radix Rubiae Yunnanensis, Radix Agapetis Mannii, Herba Polygalae Japonicae and Petiolus nelumbinis and clean remove impurity, be placed in marmite, decoct with water, intense fire boils to boiling, add kincup, Herba Elsholtziae Ciliatae, Herba oxytropis glabrae and Herba Otteliae Alismoidis again, it is (preferred: to turn slow fire boiling 20-24 minute to turn slow fire boiling 16-28 minute; Be more preferably: turn slow fire boiling 22 minutes), collecting by filtration filtrate, filtering residue adds water and again decocts, and merges twice gained filtrate after filtering;
(5) heat concentration step (4) gained filtrate to clear paste, mix with step (3) made medicated powder, then add adjuvant and mix thoroughly, make ointment, obtain ointment.
Described a kind of preparation method for the treatment of the ointment of burn and scald, it is the 0.2-0.4 of crude drug quality doubly (preferred: drenching into yellow wine amount is 0.3 times of crude drug quality) that step (1) is drenched into yellow wine amount.
Described a kind of preparation method for the treatment of the ointment of burn and scald, step (2) adds saline soak 20-30 minute of concentration 70% (preferably: soak 23-27 minute; Be more preferably: soak 25 minutes).
Described a kind of preparation method for the treatment of the ointment of burn and scald, step (3) little fire micro-stir-fry 8-16 minute is (preferred: little fire micro-stir-fry 10-14 minute; Be more preferably: the micro-stir-fry of little fire 12 minutes).
Described a kind of preparation method for the treatment of the ointment of burn and scald, the 5-8 that step (4) amount of water is boiled crude drug quality is doubly (preferred: the 6-7 that amount of water is boiled crude drug quality is doubly; Be more preferably: amount of water is 6.5 times of boiled crude drug quality).
Described a kind of preparation method for the treatment of the ointment of burn and scald, step (4) filtering residue adds water and again decocts 12-20 minute (preferably: filtering residue adds water and again decocts 14-18 minute; Be more preferably: filtering residue adds water and again decocts 16 minutes).
Described a kind of preparation method for the treatment of the ointment of burn and scald, step (5) heating concentration step (4) gained filtrate to relative density is that the clear paste (70 DEG C) of 1.05-1.15 is (preferred: heating is concentrated into the clear paste that relative density is 1.08-1.12; Be more preferably: heating is concentrated into the clear paste that relative density is 1.10).
A kind of ointment formulations science for the treatment of burn and scald provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, therapeutic effect is good, and cure rate is high, and wound surface recovers fast, without cicatrix;
2, this formula is summed up through clinical practice for many years and is formed, and has effect of promoting blood circulation and detumescence, promoting tissue regeneration and ulcer healing;
3, Chinese crude drug selected by the present invention, safety has no side effect, cheap.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Ilex purpurea Hassk.[I.chinensis Sims: base is former: be the leaf of winter plant Ilicis Purpureae.Nature and flavor: bitter; Puckery; Cool.Function cures mainly: heat-clearing and toxic substances removing; Promoting tissue regeneration and ulcer healing; Promoting blood circulation and hemostasis.Main cough due to lung-heat; Laryngopharynx swelling and pain; Dysentery; Diarrhoea; Biliary tract infection; Urinary tract infection; Angina pectoris; Burn and scald; Pyretic toxicity carbuncle; Ulcer of the lower limb; Leprelcosis; Eczema; Chilblain; Chap; Thromboangiitis obliterans; Traumatic hemorrhage.
Radix Ampelopsis Cantoniensis: base is former: be root or the Herb of vitaceae Caulis seu folium ampelopsis brevipedunculatae in Guangdong.Nature and flavor: pungent; Bitter; Cool.Gui Jing: the heart; Spleen channel.Function cures mainly: removing dampness of dispeling the wind; Heat-clearing and toxic substances removing.Main summer catches a cold; Rheumatic arthralgia; Swollen ulcer drug; Eczema eczema.
Semen Plantaginis: base is former: be the seed of Plantaginaceae plant Herba Plantaginis or Plantago depressa Willd.Chemical analysis: containing volume phlegmatic temperament, aucubin, and containing plantenolic acid, choline, adenine, succinic acid, resin etc.Nature and flavor: sweet, cold.Gui Jing: enter kidney, urinary bladder channel.Function cures mainly: diuretic, heat clearing away, tomorrow, eliminates the phlegm.Control urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, heat-damp in summer dysentery, cough ant phlegm, arthralgia chiefly caused by damp pathogen, conjunctival congestion is hidden from view.
Cortex berberidis dasystachyae: base is former: be root and the branch endothelium of the straight fringe Radix Berberidis Amurensis of Berberidaceae plant, cadmium yellow Radix Berberidis Amurensis and kansu barberry bark.Nature and flavor: bitter; Cold in nature.Gui Jing: lung; Stomach; Large intestine channel.Function cures mainly: clearing away damp-heat; Relieving heat toxin.Main hygropyretic dysentery; Jaundice; Leukorrhagia; Pyretic toxicity carbuncle.
Kincup: base is former: be the herb of ranunculaceae plant kincup, Herba Calthae Sibiricae, slender lobule kincup and Herba Calthae.Nature and flavor: acrid in the mouth; Micro-hardship; Cool in nature.Gui Jing: spleen, lung meridian.Function cures mainly: wind dispelling; Expelling summer-heat; Promoting blood circulation and detumescence.Main Common Cold; Heatstroke sun stroke; Traumatic injury; Scald burning hot wound.
Herba Elsholtziae Ciliatae: base is former: be the herb of the continuous fringe Soviet Union of labiate.Nature and flavor: acrid in the mouth; Micro-hardship; Warm in nature.Function cures mainly: dispel the wind and deliver; Blood-arresting catamenia-regulating; Subduing swelling and detoxicating.Main flu; Headache; Paralysis; Over-strained hemoptysis; Metrorrhagia; Menoxenia; Dysmenorrhea; Sore and toxic.
Radix Rubiae Yunnanensis: base is former: for the root of grass is wished in dicotyledon medicine Maguireothamnus speciosus Yunnan.Nature and flavor: sweet; Temperature.Gui Jing: Liver Channel.Function cures mainly: relaxing muscles and tendons to promote blood circulation; Promoting tissue regeneration by removing blood stasis; Take good care of QI and blood.Main rheumatalgia; Traumatic injury, menoxenia; Amenorrhea; Leukorrhagia; Puerperal arthralgia; Pulmonary tuberculosis hemoptysis; Dizzy insomnia; Anemia.
Folium et cacumen Breyniae Fruticosae: base is former: be the browse of euphorbia plant Folium et cacumen Breyniae Fruticosae.Nature and flavor: mildly bitter flavor; Cool in nature poisonous.Gui Jing: large intestine; Liver Channel.Function cures mainly: clearing heat and expelling damp; Promoting blood circulation and detoxication.Main stomachache is vomited and diarrhoea; Eczema; Herpes zoster; Dermatitis; Dermatitis rhus; Rheumatic arthralgia; Puerperal galactostasis; Pudendal pruritus.
Radix Agapetis Mannii: base is former: be the tuber of ericad styrax tonkinensis Craib ex Hart Radix Raphani.Nature and flavor: light; Cool in nature.Gui Jing: the heart; Liver; Kidney channel.Function cures mainly: heat clearing away; Dampness removing; Blood stasis dispelling.Main icterohepatitis, edema, rheumatic arthralgia; Stomach institute pain; Traumatic injury; Menoxenia; Innominate toxic swelling.
Herba Polygalae Japonicae: base is former: be herb or the root of milk wort Herba Polygalae Japonicae.Chemical analysis: root is containing triterpenoid saponin, resin, fatty oil, polygalytol.Nature and flavor: bitter in the mouth; Micro-pungent; Property is put down.Gui Jing: lung; Stomach; Heart channel.Expelling phlegm for arresting cough; Dissipating blood stasis stops blooding; Mind tranquilizing and the heart calming; Removing toxic substances and promoting subsidence of swelling.Main cough with copious phlegm; Traumatic injury, rheumatic arthralgia; Spit blood; Have blood in stool; Cardiopalmus; Insomnia; Laryngopharynx swelling and pain; Carbuncle skin infection; Venom.
Gypsum Fibrosum: nature and flavor: pungent, sweet.Gui Jing: return stomach, lung meridian.Effect: clearing away heat-fire, relieving restlessness is quenched the thirst.Cure mainly: for fever caused by exogenous pathogenic factors, high hot excessive thirst, dyspnea and cough due to lung-heat, the high Sheng of stomach-fire, headache, toothache.
Folium Polygoni Cuspidati: base is former: be the leaf of polygonaceae plant Rhizoma Polygoni Cuspidati.Nature and flavor: bitter; Property is put down.Function cures mainly: wind-damp dispelling; Relieving heat toxin.Main air wets arthralgia; Venom; Dermatitis rhus.
Herba oxytropis glabrae: base is former: be the herb of leguminous plant glabrous crazyweed.Function cures mainly: anesthesia, calm, pain relieving.Control arthralgia, toothache, neurasthenia, skin pruritus.
Petiolus nelumbinis: base is former: be petiole or the anthocaulus of nymphaeaceae plant lotus.Nature and flavor: bitter; Property is put down.Gui Jing: spleen; Urinary bladder channel.Function cures mainly: expelling summer-heat heat clearing away; Regulating QI to expel dampness.Main heat-damp in summer is uncomfortable in chest does not relax; Have loose bowels; Dysentery; Gonorrhea; Leukorrhagia.
Herba Andrographis: base is former: be herb or the leaf of acanthaceous plant Herba Andrographis.Nature and flavor: " Quanzhou book on Chinese herbal medicine ": " bitter in the mouth, cold in nature, nontoxic." return through: " Quanzhou book on Chinese herbal medicine ": " enters the heart, lung two warp." function cures mainly: heat-clearing and toxic substances removing, and removing heat from blood is subsided a swelling.Control acute bacillary dysentery, gastroenteritis, flu, epidemic encephalitis, tracheitis, pneumonia, pertussis, pulmonary tuberculosis, lung abscess, cholecystitis, hypertension, epistaxis, oropharynx swells and ache, furuncle carbuncle, burn due to hot liquid or fire, venom.Pharmacological action: 1. antibacterial action 2. antivirus action 3. other effects.
Herba Otteliae Alismoidis: base is former: be the herb of Hydrocharctaceae vegetation water Herba Plantaginis.Nature and flavor: sweet in the mouth; Light; Cold nature.Function cures mainly: removing heat-phlegm; Removing toxic substances diuresis.Main lung-heat cough with asthma; Cough up phlegm yellow thick; Edema; Dysuria; Carbuncle; Burn.
embodiment 1treat an ointment for burn and scald, be prepared from (every part of 10g) primarily of following bulk drugs: Ilex purpurea Hassk.[I.chinensis Sims 9 parts, Radix Ampelopsis Cantoniensis 7 parts, Semen Plantaginis 8 parts, Cortex berberidis dasystachyae 10 parts, kincup 7 parts, Herba Elsholtziae Ciliatae 9 parts, Radix Rubiae Yunnanensis 8 parts, Folium et cacumen Breyniae Fruticosae 6 parts, Radix Agapetis Mannii 9 parts, Herba Polygalae Japonicae 8 parts, 7 parts, Gypsum Fibrosum, Folium Polygoni Cuspidati 10 parts, Herba oxytropis glabrae 8 parts, Petiolus nelumbinis 10 parts, Herba Andrographis 8 parts, Herba Otteliae Alismoidis 9 parts.Above-mentioned a kind of preparation method for the treatment of the ointment of burn and scald is:
(1) get Ilex purpurea Hassk.[I.chinensis Sims, Folium et cacumen Breyniae Fruticosae, Folium Polygoni Cuspidati and Herba Andrographis and clean shredding, be placed in container, do not have crude drug 1cm to soak 12 minutes with vinegar, take out, put into frying pan, slow fire stir-fries to surperficial zoom, the yellow wine drenched into crude drug quality 0.2 times is mixed thoroughly, and taking-up cools;
(2) get Semen Plantaginis remove impurity to clean, add the saline soak 20 minutes of concentration 70%, take out and be placed in frying pan, moderate heat stir-fries to there being fragrance to overflow, and taking-up is pulverized, and cools;
(3) get Gypsum Fibrosum roguing, smash, be placed in refractory container, intense fire is calcined to and is popular in, taking-up cools, and is ground into coarse powder, adds candy sugar powder mixing (mass ratio of Gypsum Fibrosum powder and candy sugar powder is 4:1), the micro-stir-fry of little fire 8 minutes, takes out, pulverized 150 mesh sieves together with step (1) (2) made crude drug;
(4) get Radix Ampelopsis Cantoniensis, Cortex berberidis dasystachyae, Radix Rubiae Yunnanensis, Radix Agapetis Mannii, Herba Polygalae Japonicae and Petiolus nelumbinis and clean remove impurity, be placed in marmite, add the soak by water of boiled crude drug quality 5 times, intense fire boils to boiling, add kincup, Herba Elsholtziae Ciliatae, Herba oxytropis glabrae and Herba Otteliae Alismoidis again, turn slow fire boiling 16 minutes, collecting by filtration filtrate, filtering residue adds water and again decocts 12 minutes, merges twice gained filtrate after filtering;
(5) heat the clear paste (70 DEG C) that concentration step (4) gained filtrate to relative density is 1.05, mix with step (3) made medicated powder, then add adjuvant and mix thoroughly, make ointment, obtain ointment.
embodiment 2treat an ointment for burn and scald, be prepared from (every part of 10g) primarily of following bulk drugs: Ilex purpurea Hassk.[I.chinensis Sims 14 parts, Radix Ampelopsis Cantoniensis 13 parts, Semen Plantaginis 14 parts, Cortex berberidis dasystachyae 15 parts, kincup 16 parts, Herba Elsholtziae Ciliatae 15 parts, Radix Rubiae Yunnanensis 16 parts, Folium et cacumen Breyniae Fruticosae 14 parts, Radix Agapetis Mannii 13 parts, Herba Polygalae Japonicae 12 parts, 12 parts, Gypsum Fibrosum, Folium Polygoni Cuspidati 16 parts, Herba oxytropis glabrae 13 parts, Petiolus nelumbinis 13 parts, Herba Andrographis 15 parts, Herba Otteliae Alismoidis 12 parts.Above-mentioned a kind of preparation method for the treatment of the ointment of burn and scald is:
(1) get Ilex purpurea Hassk.[I.chinensis Sims, Folium et cacumen Breyniae Fruticosae, Folium Polygoni Cuspidati and Herba Andrographis and clean shredding, be placed in container, do not have crude drug 1cm to soak 22 minutes with vinegar, take out, put into frying pan, slow fire stir-fries to surperficial zoom, the yellow wine drenched into crude drug quality 0.4 times is mixed thoroughly, and taking-up cools;
(2) get Semen Plantaginis remove impurity to clean, add the saline soak 30 minutes of concentration 70%, take out and be placed in frying pan, moderate heat stir-fries to there being fragrance to overflow, and taking-up is pulverized, and cools;
(3) get Gypsum Fibrosum roguing, smash, be placed in refractory container, intense fire is calcined to and is popular in, taking-up cools, and is ground into coarse powder, adds candy sugar powder mixing (mass ratio of Gypsum Fibrosum powder and candy sugar powder is 4:1), the micro-stir-fry of little fire 16 minutes, takes out, pulverized 150 mesh sieves together with step (1) (2) made crude drug;
(4) get Radix Ampelopsis Cantoniensis, Cortex berberidis dasystachyae, Radix Rubiae Yunnanensis, Radix Agapetis Mannii, Herba Polygalae Japonicae and Petiolus nelumbinis and clean remove impurity, be placed in marmite, add the soak by water of boiled crude drug quality 8 times, intense fire boils to boiling, add kincup, Herba Elsholtziae Ciliatae, Herba oxytropis glabrae and Herba Otteliae Alismoidis again, turn slow fire boiling 28 minutes, collecting by filtration filtrate, filtering residue adds water and again decocts 20 minutes, merges twice gained filtrate after filtering;
(5) heat the clear paste (70 DEG C) that concentration step (4) gained filtrate to relative density is 1.15, mix with step (3) made medicated powder, then add adjuvant and mix thoroughly, make ointment, obtain ointment.
Model case: xxx, women, 22 years old.Medical history: smoked in one's hands when patient cooks because of carelessness by steam, skin surface is red and swollen, and without blister, pain is obvious, the pain that self-induction is burning, and once use ice cube to apply, pain relief is not remarkable.Through this example of people's recommendation gained ointment, be applied in scald place, one day twice, within three days, be a course for the treatment of, after patient uses three days, pain is eliminated substantially, and skin surface recovers normal, adheres to that use is after five days, and patient fully recovers, and scald place is identical with normal skin.
embodiment 3treat an ointment for burn and scald, be prepared from (every part of 10g) primarily of following bulk drugs: Ilex purpurea Hassk.[I.chinensis Sims 10 parts, Radix Ampelopsis Cantoniensis 9 parts, Semen Plantaginis 10 parts, Cortex berberidis dasystachyae 11 parts, kincup 9 parts, Herba Elsholtziae Ciliatae 11 parts, Radix Rubiae Yunnanensis 10 parts, Folium et cacumen Breyniae Fruticosae 8 parts, Radix Agapetis Mannii 10 parts, Herba Polygalae Japonicae 9 parts, 9 parts, Gypsum Fibrosum, Folium Polygoni Cuspidati 12 parts, Herba oxytropis glabrae 9 parts, Petiolus nelumbinis 11 parts, Herba Andrographis 10 parts, Herba Otteliae Alismoidis 10 parts.Above-mentioned a kind of preparation method for the treatment of the ointment of burn and scald is:
(1) get Ilex purpurea Hassk.[I.chinensis Sims, Folium et cacumen Breyniae Fruticosae, Folium Polygoni Cuspidati and Herba Andrographis and clean shredding, be placed in container, do not have crude drug 1cm to soak 14 minutes with vinegar, take out, put into frying pan, slow fire stir-fries to surperficial zoom, the yellow wine drenched into crude drug quality 0.2 times is mixed thoroughly, and taking-up cools;
(2) get Semen Plantaginis remove impurity to clean, add the saline soak 23 minutes of concentration 70%, take out and be placed in frying pan, moderate heat stir-fries to there being fragrance to overflow, and taking-up is pulverized, and cools;
(3) get Gypsum Fibrosum roguing, smash, be placed in refractory container, intense fire is calcined to and is popular in, taking-up cools, and is ground into coarse powder, adds candy sugar powder mixing (mass ratio of Gypsum Fibrosum powder and candy sugar powder is 4:1), the micro-stir-fry of little fire 10 minutes, takes out, pulverized 150 mesh sieves together with step (1) (2) made crude drug;
(4) get Radix Ampelopsis Cantoniensis, Cortex berberidis dasystachyae, Radix Rubiae Yunnanensis, Radix Agapetis Mannii, Herba Polygalae Japonicae and Petiolus nelumbinis and clean remove impurity, be placed in marmite, add the soak by water of boiled crude drug quality 6 times, intense fire boils to boiling, add kincup, Herba Elsholtziae Ciliatae, Herba oxytropis glabrae and Herba Otteliae Alismoidis again, turn slow fire boiling 20 minutes, collecting by filtration filtrate, filtering residue adds water and again decocts 14 minutes, merges twice gained filtrate after filtering;
(5) heat the clear paste (70 DEG C) that concentration step (4) gained filtrate to relative density is 1.08, mix with step (3) made medicated powder, then add adjuvant and mix thoroughly, make ointment, obtain ointment.
Model case: xxx, male, 46 years old.Main suit: accidentally by fire burn during patient work, skin surface has blister not of uniform size, and local skin has and comes off, and expose inner red tissue, to examination in hospital, patient shivers with cold, and restlessness, dry mouth and tougue, wound surface has petechia, is diagnosed as deep ii degree burn.
Wound is cleared up and after sterilizing, uses this example gained ointment, be applied in affected part, one day twice, within three days, be a course for the treatment of, after patient uses a course for the treatment of, wound surface is formed a scab gradually, without other uncomfortable diseases, adhere to three courses for the treatment of of use, patient skin returns to normally substantially, and cicatrix is not obvious, after using four courses for the treatment of, patient fully recovers.
embodiment 4treat an ointment for burn and scald, be prepared from (every part of 10g) primarily of following bulk drugs: Ilex purpurea Hassk.[I.chinensis Sims 13 parts, Radix Ampelopsis Cantoniensis 11 parts, Semen Plantaginis 12 parts, Cortex berberidis dasystachyae 14 parts, kincup 14 parts, Herba Elsholtziae Ciliatae 13 parts, Radix Rubiae Yunnanensis 14 parts, Folium et cacumen Breyniae Fruticosae 12 parts, Radix Agapetis Mannii 12 parts, Herba Polygalae Japonicae 11 parts, 10 parts, Gypsum Fibrosum, Folium Polygoni Cuspidati 14 parts, Herba oxytropis glabrae 12 parts, Petiolus nelumbinis 12 parts, Herba Andrographis 13 parts, Herba Otteliae Alismoidis 11 parts.Above-mentioned a kind of preparation method for the treatment of the ointment of burn and scald is:
(1) get Ilex purpurea Hassk.[I.chinensis Sims, Folium et cacumen Breyniae Fruticosae, Folium Polygoni Cuspidati and Herba Andrographis and clean shredding, be placed in container, do not have crude drug 1cm to soak 20 minutes with vinegar, take out, put into frying pan, slow fire stir-fries to surperficial zoom, the yellow wine drenched into crude drug quality 0.4 times is mixed thoroughly, and taking-up cools;
(2) get Semen Plantaginis remove impurity to clean, add the saline soak 27 minutes of concentration 70%, take out and be placed in frying pan, moderate heat stir-fries to there being fragrance to overflow, and taking-up is pulverized, and cools;
(3) get Gypsum Fibrosum roguing, smash, be placed in refractory container, intense fire is calcined to and is popular in, taking-up cools, and is ground into coarse powder, adds candy sugar powder mixing (mass ratio of Gypsum Fibrosum powder and candy sugar powder is 4:1), the micro-stir-fry of little fire 14 minutes, takes out, pulverized 150 mesh sieves together with step (1) (2) made crude drug;
(4) get Radix Ampelopsis Cantoniensis, Cortex berberidis dasystachyae, Radix Rubiae Yunnanensis, Radix Agapetis Mannii, Herba Polygalae Japonicae and Petiolus nelumbinis and clean remove impurity, be placed in marmite, add the soak by water of boiled crude drug quality 7 times, intense fire boils to boiling, add kincup, Herba Elsholtziae Ciliatae, Herba oxytropis glabrae and Herba Otteliae Alismoidis again, turn slow fire boiling 24 minutes, collecting by filtration filtrate, filtering residue adds water and again decocts 18 minutes, merges twice gained filtrate after filtering;
(5) heat the clear paste (70 DEG C) that concentration step (4) gained filtrate to relative density is 1.12, mix with step (3) made medicated powder, then add adjuvant and mix thoroughly, make ointment, obtain ointment.
embodiment 5treat an ointment for burn and scald, be prepared from (every part of 10g) primarily of following bulk drugs: Ilex purpurea Hassk.[I.chinensis Sims 11.5 parts, Radix Ampelopsis Cantoniensis 10 parts, Semen Plantaginis 11 parts, Cortex berberidis dasystachyae 12.5 parts, kincup 11.5 parts, Herba Elsholtziae Ciliatae 12 parts, Radix Rubiae Yunnanensis 12 parts, Folium et cacumen Breyniae Fruticosae 10 parts, Radix Agapetis Mannii 11 parts, Herba Polygalae Japonicae 10 parts, 9.5 parts, Gypsum Fibrosum, Folium Polygoni Cuspidati 13 parts, Herba oxytropis glabrae 10.5 parts, Petiolus nelumbinis 11.5 parts, Herba Andrographis 11.5 parts, Herba Otteliae Alismoidis 10.5 parts.Above-mentioned a kind of preparation method for the treatment of the ointment of burn and scald is:
(1) get Ilex purpurea Hassk.[I.chinensis Sims, Folium et cacumen Breyniae Fruticosae, Folium Polygoni Cuspidati and Herba Andrographis and clean shredding, be placed in container, do not have crude drug 1cm to soak 17 minutes with vinegar, take out, put into frying pan, slow fire stir-fries to surperficial zoom, the yellow wine drenched into crude drug quality 0.3 times is mixed thoroughly, and taking-up cools;
(2) get Semen Plantaginis remove impurity to clean, add the saline soak 25 minutes of concentration 70%, take out and be placed in frying pan, moderate heat stir-fries to there being fragrance to overflow, and taking-up is pulverized, and cools;
(3) get Gypsum Fibrosum roguing, smash, be placed in refractory container, intense fire is calcined to and is popular in, taking-up cools, and is ground into coarse powder, adds candy sugar powder mixing (mass ratio of Gypsum Fibrosum powder and candy sugar powder is 4:1), the micro-stir-fry of little fire 12 minutes, takes out, pulverized 150 mesh sieves together with step (1) (2) made crude drug;
(4) get Radix Ampelopsis Cantoniensis, Cortex berberidis dasystachyae, Radix Rubiae Yunnanensis, Radix Agapetis Mannii, Herba Polygalae Japonicae and Petiolus nelumbinis and clean remove impurity, be placed in marmite, add the soak by water of boiled crude drug quality 6.5 times, intense fire boils to boiling, add kincup, Herba Elsholtziae Ciliatae, Herba oxytropis glabrae and Herba Otteliae Alismoidis again, turn slow fire boiling 22 minutes, collecting by filtration filtrate, filtering residue adds water and again decocts 16 minutes, merges twice gained filtrate after filtering;
(5) heat the clear paste (70 DEG C) that concentration step (4) gained filtrate to relative density is 1.10, mix with step (3) made medicated powder, then add adjuvant and mix thoroughly, make ointment, obtain ointment.
test example 1a kind of clinical practice for the treatment of the ointment (embodiment 5) of burn and scald of gained of the present invention:
Choose crowd: in February ,-2015 in March, 2014, according to medical case history, in patient 275 example of six hospitals screening burn and scald, age 6-72 year, 32.4 ± 2.3 years old mean age, male patient 140 example, female patient 135 example, wherein scald patient 89 example, fire burn patient 62 example, chemical burn 54 example, burned patient 70 example caused by other reasons.
Before test, patient is divided into two groups at random, experimental group 155 example and matched group 120 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Remove wound before medication, retain residual skin as far as possible, have vesicle person to try one's best drawing liquid or puncture compressing sepage is flowed out, wound surface sterilization.Experimental group uses products obtained therefrom of the present invention, is applied in affected part, one day twice, within three days, is a course for the treatment of; Matched group uses other conventional medicines (SHENGFU GAO, salve for treating burn and scald, traumatology spirit spray etc.).During medication, Continuous Observation is carried out to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: clinical uncomfortable disease is all eliminated, and wound face heals, without cicatrix; (2) take a turn for the better: clinical uncomfortable disease is eliminated substantially, and wound face does not heal completely, part incrustation; (3) invalid: clinical symptoms has no improvement, wound face does not heal.Total effective rate=cure rate+improvement rate.
Clinical effectiveness: after the medication of three courses for the treatment of, the therapeutic outcome of two groups is as follows:
Curing patient in experimental group is 125 examples, and cure rate is 80.6%, and improvement patient is 28 examples, improvement rate is 18.1%, and total effective rate is 98.7%, and the healing patient in matched group is 70 examples, cure rate is 58.3%, improvement patient is 34 examples, and improvement rate is 28.3%, total effective rate 86.6%, be starkly lower than the therapeutic effect of experimental group, illustrate that products obtained therefrom of the present invention is evident in efficacy, efficient recovery wound surface can be had, control inflammation.
The Chinese medicine used in the present invention, Ilex purpurea Hassk.[I.chinensis Sims promoting tissue regeneration and ulcer healing, Radix Ampelopsis Cantoniensis, Cortex berberidis dasystachyae heat-clearing and toxic substances removing, the heat clearing away of Semen Plantaginis diuretic, kincup promoting blood circulation and detumescence, Herba Elsholtziae Ciliatae subduing swelling and detoxicating, Radix Rubiae Yunnanensis promoting tissue regeneration by removing blood stasis, Folium et cacumen Breyniae Fruticosae promoting blood circulation and detoxication, Radix Agapetis Mannii clearing away heat-damp and promoting diuresis, Herba Polygalae Japonicae dissipating blood stasis stops blooding, Gypsum Fibrosum clearing away heat-fire, Folium Polygoni Cuspidati expelling wind and removing dampness, Herba oxytropis glabrae sedation-analgesia, Petiolus nelumbinis regulating QI to expel dampness, Herba Andrographis antibiotic and sterilizing, Herba Otteliae Alismoidis removing toxic substances diuresis, multiple medical material synergism, has effectively given play to effect of promoting blood circulation and detumescence, promoting tissue regeneration and ulcer healing.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. treat an ointment for burn and scald, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Ilex purpurea Hassk.[I.chinensis Sims 9-14; Radix Ampelopsis Cantoniensis 7-13; Semen Plantaginis 8-14; Cortex berberidis dasystachyae 10-15; Kincup 7-16; Herba Elsholtziae Ciliatae 9-15; Radix Rubiae Yunnanensis 8-16; Folium et cacumen Breyniae Fruticosae 6-14; Radix Agapetis Mannii 9-13; Herba Polygalae Japonicae 8-12; Gypsum Fibrosum 7-12; Folium Polygoni Cuspidati 10-16; Herba oxytropis glabrae 8-13; Petiolus nelumbinis 10-13; Herba Andrographis 8-15; Herba Otteliae Alismoidis 9-12.
2. a kind of ointment for the treatment of burn and scald as claimed in claim 1, is characterized in that, Ilex purpurea Hassk.[I.chinensis Sims 10-13; Radix Ampelopsis Cantoniensis 9-11; Semen Plantaginis 10-12; Cortex berberidis dasystachyae 11-14; Kincup 9-14; Herba Elsholtziae Ciliatae 11-13; Radix Rubiae Yunnanensis 10-14; Folium et cacumen Breyniae Fruticosae 8-12; Radix Agapetis Mannii 10-12; Herba Polygalae Japonicae 9-11; Gypsum Fibrosum 9-10; Folium Polygoni Cuspidati 12-14; Herba oxytropis glabrae 9-12; Petiolus nelumbinis 11-12; Herba Andrographis 10-13; Herba Otteliae Alismoidis 10-11.
3. a kind of ointment for the treatment of burn and scald as claimed in claim 1, is characterized in that, Ilex purpurea Hassk.[I.chinensis Sims 11.5; Radix Ampelopsis Cantoniensis 10; Semen Plantaginis 11; Cortex berberidis dasystachyae 12.5; Kincup 11.5; Herba Elsholtziae Ciliatae 12; Radix Rubiae Yunnanensis 12; Folium et cacumen Breyniae Fruticosae 10; Radix Agapetis Mannii 11; Herba Polygalae Japonicae 10; Gypsum Fibrosum 9.5; Folium Polygoni Cuspidati 13; Herba oxytropis glabrae 10.5; Petiolus nelumbinis 11.5; Herba Andrographis 11.5; Herba Otteliae Alismoidis 10.5.
4. a kind of preparation method for the treatment of the ointment of burn and scald as described in as arbitrary in claim 1-3, it is characterized in that, step is as follows:
(1) get Ilex purpurea Hassk.[I.chinensis Sims, Folium et cacumen Breyniae Fruticosae, Folium Polygoni Cuspidati and Herba Andrographis and clean shredding, be placed in container, do not have crude drug 1cm to soak 12-22 minute (preferably: soak 14-20 minute with vinegar; Be more preferably: soak 17 minutes), take out, put into frying pan, slow fire stir-fries to surperficial zoom, drenches and mixes thoroughly into yellow wine, and taking-up cools;
(2) get Semen Plantaginis remove impurity to clean, add the saline soak of concentration 70%, take out and be placed in frying pan, moderate heat stir-fries to there being fragrance to overflow, and taking-up is pulverized, and cools;
(3) get Gypsum Fibrosum roguing, smash, be placed in refractory container, intense fire is calcined to and is popular in, taking-up cools, and is ground into coarse powder, adds candy sugar powder mixing (mass ratio of Gypsum Fibrosum powder and candy sugar powder is 4:1), the micro-stir-fry of little fire, takes out, pulverized 150 mesh sieves together with step (1) (2) made crude drug;
(4) get Radix Ampelopsis Cantoniensis, Cortex berberidis dasystachyae, Radix Rubiae Yunnanensis, Radix Agapetis Mannii, Herba Polygalae Japonicae and Petiolus nelumbinis and clean remove impurity, be placed in marmite, decoct with water, intense fire boils to boiling, add kincup, Herba Elsholtziae Ciliatae, Herba oxytropis glabrae and Herba Otteliae Alismoidis again, it is (preferred: to turn slow fire boiling 20-24 minute to turn slow fire boiling 16-28 minute; Be more preferably: turn slow fire boiling 22 minutes), collecting by filtration filtrate, filtering residue adds water and again decocts, and merges twice gained filtrate after filtering;
(5) heat concentration step (4) gained filtrate to clear paste, mix with step (3) made medicated powder, then add adjuvant and mix thoroughly, make ointment, obtain ointment.
5. a kind of preparation method for the treatment of the ointment of burn and scald as claimed in claim 4, is characterized in that, it is the 0.2-0.4 of crude drug quality doubly (preferred: drenching into yellow wine amount is 0.3 times of crude drug quality) that step (1) is drenched into yellow wine amount.
6. a kind of preparation method for the treatment of the ointment of burn and scald as claimed in claim 4, is characterized in that, it is (preferred: to soak 23-27 minute that step (2) adds saline soak 20-30 minute of concentration 70%; Be more preferably: soak 25 minutes).
7. a kind of preparation method for the treatment of the ointment of burn and scald as claimed in claim 4, is characterized in that, step (3) little fire micro-stir-fry 8-16 minute is (preferred: little fire micro-stir-fry 10-14 minute; Be more preferably: the micro-stir-fry of little fire 12 minutes).
8. a kind of preparation method for the treatment of the ointment of burn and scald as claimed in claim 4, is characterized in that, the 5-8 that step (4) amount of water is boiled crude drug quality is doubly (preferred: the 6-7 that amount of water is boiled crude drug quality doubly; Be more preferably: amount of water is 6.5 times of boiled crude drug quality).
9. a kind of preparation method for the treatment of the ointment of burn and scald as claimed in claim 4, is characterized in that, step (4) filtering residue add water again decoct 12-20 minute (preferred: filtering residue adds water and again decocts 14-18 minute; Be more preferably: filtering residue adds water and again decocts 16 minutes).
10. a kind of preparation method for the treatment of the ointment of burn and scald as claimed in claim 4, it is characterized in that, step (5) heating concentration step (4) gained filtrate to relative density is that the clear paste of 1.05-1.15 is (preferred: heating is concentrated into the clear paste that relative density is 1.08-1.12; Be more preferably: heating is concentrated into the clear paste that relative density is 1.10).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510610086.4A CN105125769A (en) | 2015-09-23 | 2015-09-23 | Ointment for treating burns and scalds and preparation method |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510610086.4A CN105125769A (en) | 2015-09-23 | 2015-09-23 | Ointment for treating burns and scalds and preparation method |
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| Publication Number | Publication Date |
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| CN105125769A true CN105125769A (en) | 2015-12-09 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105456578A (en) * | 2016-01-15 | 2016-04-06 | 李丽 | Traditional Chinese medicine ointment for treating scars and preparing method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103251727A (en) * | 2013-04-25 | 2013-08-21 | 康付英 | Chinese medicine powder and paste for treating burn |
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2015
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103251727A (en) * | 2013-04-25 | 2013-08-21 | 康付英 | Chinese medicine powder and paste for treating burn |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105456578A (en) * | 2016-01-15 | 2016-04-06 | 李丽 | Traditional Chinese medicine ointment for treating scars and preparing method thereof |
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Address after: 561000 Guizhou province Xixiu District of Anshun City Zhonghua Road No. 45 Huaxia District 1 building 1-502 Applicant after: Li Xiaotao Address before: 250000 Ji'nan, China Hi tech Zone, Shandong Chong Hua Road, No. 1586 Applicant before: Li Xiaotao |
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Application publication date: 20151209 |