CN110214008A - 一种非布司他控释组合物及其制备方法 - Google Patents

一种非布司他控释组合物及其制备方法 Download PDF

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Publication number
CN110214008A
CN110214008A CN201880008325.0A CN201880008325A CN110214008A CN 110214008 A CN110214008 A CN 110214008A CN 201880008325 A CN201880008325 A CN 201880008325A CN 110214008 A CN110214008 A CN 110214008A
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CN
China
Prior art keywords
febustat
controlled release
floating
item
preparation
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Pending
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CN201880008325.0A
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English (en)
Inventor
顾国祥
王立坤
王捷
张凤娥
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Jiangsu Hengrui Medicine Co Ltd
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Jiangsu Hengrui Medicine Co Ltd
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Publication of CN110214008A publication Critical patent/CN110214008A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents

Abstract

一种非布司他控释组合物及其制备方法，所述非布司他控释组合物含有非布司他速释组分和非布司他漂浮组分，从而可以有效降低血浆中药物浓度峰值，延长有效药物作用时间，减少副作用，提高患者的依从性。

Description

PCT国内申请，说明书已公开。

Claims (32)

  1. PCT国内申请，权利要求书已公开。
CN201880008325.0A 2017-06-14 2018-06-13 一种非布司他控释组合物及其制备方法 Pending CN110214008A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201710448092 2017-06-14
CN2017104480923 2017-06-14
PCT/CN2018/091101 WO2018228440A1 (zh) 2017-06-14 2018-06-13 一种非布司他控释组合物及其制备方法

Publications (1)

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CN110214008A true CN110214008A (zh) 2019-09-06

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CN201880008325.0A Pending CN110214008A (zh) 2017-06-14 2018-06-13 一种非布司他控释组合物及其制备方法

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CN (1) CN110214008A (zh)
TW (1) TWI745598B (zh)
WO (1) WO2018228440A1 (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112336696A (zh) * 2020-12-01 2021-02-09 苏州中化药品工业有限公司 一种长效脉冲制剂及其制备方法

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112972396A (zh) * 2019-12-17 2021-06-18 南京海辰药业股份有限公司 一种非布司他控释组合物及其制备方法

Citations (5)

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US5626876A (en) * 1988-02-05 1997-05-06 Lts Lohmann Therapie-Systeme Gmbh & Co., Kg Floating system for oral therapy
CN101658505A (zh) * 2009-09-29 2010-03-03 北京华禧联合科技发展有限公司 非布索坦的缓释制剂及其制备方法
WO2010136823A1 (en) * 2009-05-29 2010-12-02 University Of Dundee Angina treatment
CN103210084A (zh) * 2010-06-16 2013-07-17 武田制药美国有限公司 黄嘌呤氧化还原酶抑制剂或黄嘌呤氧化酶抑制剂的新的改进的释放剂型
CN103432131A (zh) * 2013-09-11 2013-12-11 中国药科大学 一种含有盐酸吡格列酮和盐酸二甲双胍的复方制剂及其制备方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5626876A (en) * 1988-02-05 1997-05-06 Lts Lohmann Therapie-Systeme Gmbh & Co., Kg Floating system for oral therapy
WO2010136823A1 (en) * 2009-05-29 2010-12-02 University Of Dundee Angina treatment
CN101658505A (zh) * 2009-09-29 2010-03-03 北京华禧联合科技发展有限公司 非布索坦的缓释制剂及其制备方法
CN103210084A (zh) * 2010-06-16 2013-07-17 武田制药美国有限公司 黄嘌呤氧化还原酶抑制剂或黄嘌呤氧化酶抑制剂的新的改进的释放剂型
CN103432131A (zh) * 2013-09-11 2013-12-11 中国药科大学 一种含有盐酸吡格列酮和盐酸二甲双胍的复方制剂及其制备方法

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ANH Q. VO ET AL.: "A novel floating controlled release drug delivery system prepared by hot-melt extrusion", 《EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS》 *
元英进主编: "《制药工艺学下册》", 31 December 2006, 化学工业出版社 *
冯小权等: "胃漂浮片的研究进展及其在中药制剂中的应用", 《广州中医药大学学报》 *
方亮主编: "《药剂学》", 31 March 2016, 中国医药科技出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112336696A (zh) * 2020-12-01 2021-02-09 苏州中化药品工业有限公司 一种长效脉冲制剂及其制备方法
CN112336696B (zh) * 2020-12-01 2022-08-05 苏州中化药品工业有限公司 一种长效脉冲制剂及其制备方法

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WO2018228440A1 (zh) 2018-12-20
TW201904572A (zh) 2019-02-01
TWI745598B (zh) 2021-11-11

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