CN110201078A - It is a kind of for treating the external-applied ointment and its preparation process of exanthemv - Google Patents

It is a kind of for treating the external-applied ointment and its preparation process of exanthemv Download PDF

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CN110201078A
CN110201078A CN201910525112.1A CN201910525112A CN110201078A CN 110201078 A CN110201078 A CN 110201078A CN 201910525112 A CN201910525112 A CN 201910525112A CN 110201078 A CN110201078 A CN 110201078A
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parts
exanthemv
external
treating
applied ointment
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韩利志
王淑玲
宫相东
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Abstract

The present invention relates to a kind of for treating the external-applied ointment and its preparation process of exanthemv, which festers especially suitable for treatment diabetes, bedsore, belongs to the external-applied ointment technical field for the treatment of exanthemv.Raw material including following parts by weight: 10-30 parts of Cortex Phellodendri, 10-30 parts of the coptis, 10-30 parts of rheum officinale, 5-20 parts of borneol, 10-200 parts of radix paeoniae rubra, 20-500 parts of Radix Salviae Miltiorrhizae, 20-60 parts of magnetite, 20-60 parts of gypsum, 5-50 parts of dragon's blood, 20-100 parts of safron, 10-20 parts of beeswax.Clearing heat and detoxicating, expelling the stasis for the new of the invention, festering to treatment has special effect, especially treatment diabetes, bedsore, significant effect.

Description

It is a kind of for treating the external-applied ointment and its preparation process of exanthemv
Technical field
The present invention relates to a kind of for treating the external-applied ointment and its preparation process of exanthemv, the ointment especially suitable for Treatment diabetes fester, bedsore, belong to treatment exanthemv external-applied ointment technical field.
Background technique
Currently, diabetes and cerebral infarction, cerebral hemorrhage belong to common disease, frequently-occurring disease, it is most common that diabetes belong to diabetes Complication, and cerebral infarction and cerebral hemorrhage will lead to patient paralysis, long-term bed can induce bedsore, below to diabetes, cotton-padded mattress Sore and current treatment method are briefly described:
Diabetes are also known as diabetic gangrene, belong to Chinese medicine " gangrene of finger or toe " model with Buerger's disease, atherosclerotic occlusive disease Farmland.Traditional Chinese medicine thinks that the disease is mainly deficiency of both qi and yin, obstruction of collaterals by blood stasis, and qi and blood cannot be caused by sensible four limbs.Diabetes are most common In diabetes medical history length, long-term blood glucose controls the bad middle-aged and the old, is one of diabetes severe complication, disease incidence 15%- 20%, it is the main reason for amputation disables.The performance of diabetes initial stage is it is numb, send out cool, perceptibility reduces, vulnerable to wound, shallowly Table wound is not easy to heal, often easily ignored, and the later period deteriorates very fast, it is likely that faces amputation in one week.
Currently, the method for the treatment of diabetes predominantly controls blood glucose, blood lipid and blood pressure in terms of doctor trained in Western medicine, improves blood and follow Ring improves peripheral neuropathy, the dressing processing etc. using antibiotic anti-infective therapy, to ulcer wound surface.Chemical drugs are not yet Specifically for the drug of diabetes, general treatment method is conservative symptomatic treatment, while common chemicals have obviously Side effect, diabetic need eventually to medication, long-term administration can generate adverse effect to body；
The patients such as cerebral infarction, cerebral hemorrhage, fracture clinically long-term bed cannot turn over, and blood circulation function is easily caused to subtract It moves back, causes the germinating of the positions such as tail sacrum portion, back to be festered, septicemia can be caused and threat to life, China is with social astogeny journey The intensification of degree, the disease incidence of bedsore continue to improve.
Currently, some conventional medicines are for bedsore and disease especially large area bedsore of festering, effect is less desirable, some Drug is formed a scab in patient using rear surface, and appearance is seemed and seemingly cured, but actually certain bacterial growths are more savage (such as anaerobic bacteria) oozes out dope from scab film both sides so that keeping the open sore part rotten always to periosteum.With Western medicine antimicrobial be applied with and its His anti-inflammatory drug carries out symptomatic treatment, and effect is not all good enough yet.
At present, it would be highly desirable to the external-applied ointment and its preparation work of a kind for the treatment of exanthemv that can solve above-mentioned technical problem occur Skill.
Summary of the invention
It is an object of the invention to solve the shortcomings of the prior art, a kind of clearing heat and detoxicating, dissolving stasis life is provided Flesh, festering to treatment has special effect, especially treatment diabetes, bedsore, the external-applied ointment of effective treatment exanthemv And its preparation process.
A kind of external-applied ointment for treating exanthemv is characterized in that the raw material including following parts by weight: Cortex Phellodendri 10- 30 parts, 10-30 parts of the coptis, 10-30 parts of rheum officinale, 5-20 parts of borneol, 10-200 parts of radix paeoniae rubra, 20-500 parts of Radix Salviae Miltiorrhizae, magnetite 20-60 Part, 20-60 parts of gypsum, 5-50 parts of dragon's blood, 20-100 parts of safron, 10-20 parts of beeswax, 10-30 parts of calamine, Radix Notoginseng 30-50 Part；
It preferably, further include 10-200 parts of honeysuckle, 5-15 parts of cow-bezoar in the raw material；
It preferably, further include the raw material of following parts by weight in the raw material: 20-100 parts of vaseline.
A kind of preparation process of external-applied ointment that treating exanthemv, be characterized in that the following steps are included:
1, take 10-30 parts of Cortex Phellodendri, 10-30 parts of the coptis, 10-30 parts of rheum officinale, 10-200 parts of radix paeoniae rubra, 20-500 parts of Radix Salviae Miltiorrhizae clean after from So dry；
2, above-mentioned Chinese medicine is ground to powdered, be placed in container, 80-300 parts of sesame oil are added into container；
3, container is placed in steamer, it is cool to set using moderate heat Steam by water bath 1.5-2.5 hours, filter out medical fluid；
4,5-20 parts of borneols are added in 10-20 parts of beeswaxs, are placed in container and are melted using moderate heat Steam by water bath to beeswax；
5, the medical fluid of step 4 is uniformly mixed with the mixture of step 5, pour into while hot 10-30 parts of calamines, 20-60 parts of magnetites, 20-60 parts of gypsum, 30-50 portions of Radix Notoginseng, 20-100 parts of kumkums；
6,5-50 parts of dragon's blood, 50-100 parts of ethyl alcohol are added in the resulting mixture of step 6 and are uniformly mixed；
7, it is cool but, close the lid preservation, to be installed, pending.
Raw material drug effect of the invention is analyzed as follows:
Cortex Phellodendri: detoxification sore treatment effect.Especially more significant in both the coptis, Cortex Phellodendri amount Synergistic antimicrobial, antiulcer: Cortex Phellodendri is to experiment Property ulcer has significant protective effect；
Calamine: for natural magnesium zinc, it can inhibit local Portugal as anti-corrosion, convergence, treatment scytitis or surface injury external application The growth of grape coccus, can partially absorb wound extract, there is convergence, protective effect；The coptis: heat-clearing and damp-drying drug, purging fire for removing toxin.Pharmacology is made With: antibacterial action, antifungic action, antivirus action, anti-amoeba effect, anti-inflammatory, antioxidation, anti-ulcer effect；
Rheum officinale: heat and toxic materials clearing away, clearing heat-fire, removing pattogenic heat from the blood and toxic material from the body, dispelling stasis of blood and stimulating the menstrual flow.For carbuncle swells furunculosis, traumatic injury burn and scald.Gold Honeysuckle flower: clearing heat and detoxicating, ulcer serious case of furuncle.Anti inflammatory detoxication effect, has stronger scattered carbuncle to carbuncle swells furunculosis, acute appendicitis pulmonary abscess
Detumescence, clearing heat and detoxicating, antiinflammation；
Borneol: this product is clearing heat and detoxicating, erosion prevention and muscle growing, the function of detumescence, is used for sore swell and ache curative, does not hold back after bursting；
Radix Notoginseng: dissipating stasis of blood detumescence ding-tong, and significant hematopoiesis function can tighten and improve Coronary microcirculation, expand the effect of blood vessel； Analgesic activity；Anti-inflammatory effect；Antitumor action；Antioxidation；
Radix paeoniae rubra: clearing heat and cooling blood, removing blood stasis and acesodyne.Radix paeoniae rubra inhibits the effect of a variety of coccuses, bacillus and certain pathogenic fungus, dissipates the stasis of blood Analgesic；
Radix Salviae Miltiorrhizae: promoting blood circulation, inducing meastruation to relieve menalgia, cool blood to disappear carbuncle.Pharmacological research finds antibacterial anti-inflammatory: the total-tanshinone in Radix Salviae Miltiorrhizae has Antibacterial action can inhibit staphylococcus aureus and its antibody-resistant bacterium；
Magnetite: metal-inflicted wound is controlled, sore, analgesic, it is applied in magnetite end；
Gypsum: it forges deposited: myogenic hygroscopic sore.Ulcer sores are controlled outside, bursts and does not close up, the burning hot wound of soup；
Dragon's blood: promoting blood circulation analgesic therapy, stagnation resolvation, expelling pus and promoting granulation.There is anti-inflammatory, antibacterial, anti thrombotic action, have an impact to cyclic nucleotide, influences Fibrinolytic activity etc.；
Safron: activating microcirculation and removing stasis medicinal, removing pattogenic heat from the blood and toxic material from the body.Safron hot water extract has significant anticoagulant effect；
Cow-bezoar: tool analgesia, antipyretic, antipyretic and antidote functions are stronger, and for festering, raw sore swells pain has anti-inflammatory, the disease-resistant micro- life of original Object, effect that is anti-oxidant and inhibiting tumour growth；
Beeswax: inducing astrigency, sore, myogenic, analgesic.It is used for unhealing ulcer outside, ulcer on the shank to be rotten to the corn, wound, burn vaseline: medicinal Auxiliary material is used for ointment bases and lubricant.
The present invention carries out above-mentioned Chinese medicine fried in proportion, and ointment is then made for festering patient's external application, achieves fabulous Clinical effectiveness.Use clearing heat and detoxicating, expelling the stasis for the new for principle of reatment according to theory of traditional Chinese medical science, attack malicious method with nontoxic, through pair Thousands of patient clinicals use, efficient up to 99% or more, and cure rate is up to 93.34% or more, it is sufficient to illustrate clinical effectiveness.Among the above Medicine buying is convenient, and festering to treatment has peculiar effect, daily only to use 1-4 times, and general patient of festering suffers from use, applying outside Face can take effect, there is positive effect, excellent treatment effect in 5 days for 2 days.
Specific embodiment
The technical scheme in the embodiments of the invention will be clearly and completely described below, it is clear that described implementation Example is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field is common Technical staff's every other embodiment obtained without making creative work belongs to the model that the present invention protects It encloses.
Embodiment 1
A kind of external-applied ointment for treating exanthemv of the present embodiment, the raw material including following parts by weight: 10 grams of Cortex Phellodendri, the coptis 10 Gram, 10 grams of rheum officinale, 5 grams of borneol, 10 grams of radix paeoniae rubra, 20 grams of Radix Salviae Miltiorrhizae, 20 grams of magnetite, 20 grams of gypsum, 5 grams of dragon's blood, 20 grams of safron, bee 10 grams of wax, 10 parts of calamine, 30 parts of Radix Notoginseng.
Embodiment 2
A kind of external-applied ointment for treating exanthemv of the present embodiment, the raw material including following parts by weight: 30 grams of Cortex Phellodendri, the coptis 30 Gram, 30 grams of rheum officinale, 20 grams of borneol, 200 grams of radix paeoniae rubra, 500 grams of Radix Salviae Miltiorrhizae, 60 grams of magnetite, 60 grams of gypsum, 50 grams of dragon's blood, safron 100 Gram, 20 grams of beeswax, 30 parts of calamine, 50 parts of Radix Notoginseng.
Embodiment 3
A kind of external-applied ointment for treating exanthemv of the present embodiment, the raw material including following parts by weight: 20 grams of Cortex Phellodendri, the coptis 20 Gram, 20 grams of rheum officinale, 13 grams of borneol, 100 grams of radix paeoniae rubra, 260 grams of Radix Salviae Miltiorrhizae, 40 grams of magnetite, 40 grams of gypsum, 26 grams of dragon's blood, safron 60 Part gram, 15 grams of beeswax, 20 parts of calamine, 40 parts of Radix Notoginseng.
Embodiment 4
A kind of external-applied ointment for treating exanthemv of the present embodiment, the difference from embodiment 1 is that: it further include honeysuckle 10 Gram, 5 grams of cow-bezoar, 20 grams of vaseline.
Embodiment 5
A kind of external-applied ointment for treating exanthemv of the present embodiment, the difference from example 2 is that: it further include honeysuckle 200 grams, 15 grams of cow-bezoar, 100 grams of vaseline.
Embodiment 6
A kind of preparation process of the external-applied ointment for treating exanthemv of the present embodiment, comprising the following steps:
1, take 10-30 parts of Cortex Phellodendri, 10-30 parts of the coptis, 10-30 parts of rheum officinale, 10-200 parts of radix paeoniae rubra, 20-500 parts of Radix Salviae Miltiorrhizae clean after from So dry；
2, above-mentioned Chinese medicine is ground to powdered, be placed in container, 80-300 parts of sesame oil are added into container；
3, container is placed in steamer, it is cool to set using moderate heat Steam by water bath 1.5-2.5 hours, filter out medical fluid；
4,5-20 parts of borneols are added in 10-20 parts of beeswaxs, are placed in container and are melted using moderate heat Steam by water bath to beeswax；
5, the medical fluid of step 4 is uniformly mixed with the mixture of step 5, pour into while hot 10-30 parts of calamines, 20-60 parts of magnetites, 20-60 parts of gypsum, 30-50 portions of Radix Notoginseng, 20-100 parts of kumkums；
6,5-50 parts of dragon's blood, 50-100 parts of ethyl alcohol are added in the resulting mixture of step 6 and are uniformly mixed；
7, it is cool but, close the lid preservation, to be installed, pending.
Embodiment 7
A kind of preparation process of external-applied ointment for treating exanthemv of the present embodiment, the difference with embodiment 6 are:
It further include 10-200 parts of honeysuckle, 5-15 parts of cow-bezoar in the raw material of step 1；
Vaseline in step 6 also added with 20-100 parts.
Below by specific treatment case, illustrate the therapeutic effect of the invention.Case 1: so-and-so hall medical centre pair of Yantai 100 patients of festering obtain order through clinic trial after a period of time
The satisfied curative effect of people, wherein the small open sore part patient of 30 neopathies is respectively embrocated once sooner or later using ointment of the invention, Wound can restore in three days to one week, and within 20 square centimeters, depth uses 50 open sore part areas within 2 centimetres Ointment of the invention, early, middle and late respectively to embrocate primary, time healing in one month or so, 20 open sore part areas are larger, deeper Patient embrocated primary, time healing in three months or so every 4 hours using ointment of the invention.
Case 2: so-and-so hospital of Tianjin obtains satisfactory curative effect by clinical application 200, wherein male 140, Female 60, the age 64 years old to 83 years old, 73.5 years old average, case is Patients with Stroke, and many places bedsore gives conventional disappear first Poison, debridement, then external application it is of the invention treatment exanthemv external-applied ointment, severe three times a day, moderate patient daily one to Secondary, slight person is not required to debridement, can directly be applied with, and sore face is kept not to be pressurized, the healing of 2~3 days sore faces of mild person, moderate and again It heals within disease person 5~7 days, total effective rate is up to 99% and preventing from scar, and many patients are because routed sore causes 39 DEG C of high fever or more, for a long time not It moves back, is controlled quickly with the state of an illness after the medicine；
Mr. Wang, female, 56 years old, pelvic bone bottom patient have diameter 19cm long, four degree of 3cm wide fester it is rotten to fascia, it can be seen that bone Slag, houseful cacosmia is unpleasant, 39 DEG C of body temperature, using ointment of the invention, embrocates daily 4 times, cures after treating two weeks, applicant Proved by clinical practice: ointment of the present invention festers to diabetes, bedsore, acne, canker sore, furuncle, insect-bite, swells Tumor, prickly heat, scald, verruca vulgaris etc. have obvious curative effects；
Mr. Wang, female, 53 years old, thigh osteocarcinoma was in semi-annular jade pendant top hospital surgical of giving birth, afterwards because obtaining diabetes, because the heat lamp that has a pain in the leg is roasting broken by lamp , do not heal always, suppurate always, went to primary Yu Huangding hospital to operate on cleaning once every two months, be continued for half It as long as year, with ointment of the invention, respectively embrocates sooner or later once, two weeks just thoroughly cures, and has pass by within 2 years again not multiple It sent out；
Week certain, male 73 years old, because of cerebral thrombosis long-term bed, suffers from bedsore, more than 5 years, and because blood glucose is high, has used various methods It does not cure, has used ointment of the invention upon somebody's introduction, at a bit light rotten five or six less than one centimeter or so of the bedsore of whole body, With ointment one and a half months or so of the invention, primary, just healing is respectively embrocated sooner or later daily, stress in hip two rotten to bone Wound have seven or eight centimeters big, overgrow with new meat, 4 half a months healings by 3 half a months；
Poplar, male, 62 years old, always rotten lower limb, blood glucose was high, all blacked from calf to toe finger, on instep at focile ankle It is rotten to arrive bone more than a year, it is not also cured with various medicines, amputation is suggested by hospital, has used medicine of the invention after being introduced Cream, it is early, middle and late respectively to embrocate primary, just healing in three months, and also the color of shank and foot becomes normal color by blacking；
Lee, male, 03 months 1 years old, his mother endured a basin maize gruel, and because naughty, Lee is reached into maize gruel, hand from It is taken out in basin at a glance, hand all scalds rotten, and pinkie only remains a bone, his mother arrives Qixia the People's Hospital, hospital with him It says and does not control, higher level hospital is allowed to control, his mother has turned several pharmacies with her, all says and does not control, after being introduced, embrocates this hair Bright ointment, one day interval are embrocated once for 3 hours, and the hand scald position less than month Lee grows new meat, less than one Month, the new meat overall length of the hand of Lee is good, and does not have scar a bit.
The present invention carries out above-mentioned Chinese medicine fried in proportion, and ointment is then made for festering patient's external application, achieves fabulous Clinical effectiveness.Use clearing heat and detoxicating, expelling the stasis for the new for principle of reatment according to theory of traditional Chinese medical science, attack malicious method with nontoxic, through pair Thousands of patient clinicals use, efficient up to 100% or more, it is sufficient to illustrate clinical effectiveness.Chinese medicine material buying side of the invention Just, festering to treatment has peculiar effect, need to only use 1-4 times daily, and general patient of festering suffers from face in use, applying outside, and 2 It can take effect, and have positive effect, excellent treatment effect in 5 days.
Using the external-applied ointment for the treatment of exanthemv of the invention, the ointment of the treatment exanthemv of current commercial type 30 patients of festering are treated respectively, treating total course for the treatment of is 30 days, and usage is that external-applied ointment is directly applied to rotten position, 2 times/day of usage, control group be give pharmacy sale treatment fester ointment smearing, 2 times a day.
Observation method
Each patient all records medical history, sign, diagnosis, painful area and property and related physics, physiology inspection.
Efficacy assessment standard
Recovery from illness: illness all disappears after treatment, reaches clinical cure standard；
Effective: state of an illness sign is obviously improved after treatment；
Effective: state of an illness sign makes moderate progress after treatment；
It is invalid: unchanged before and after treatment.
Treatment analysis
By the collated analysis of patient clinical data, by treatment group and control group in recovery from illness, effective, effective and invalid four standards It is compared.
Two groups of therapeutic effects are relatively shown in Table 1.Use the external-applied ointment effective percentage for the treatment of exanthemv of the invention for 99%, Cure rate is 93.34%, better than the cure rate of control group 36.66%.
1: two group of therapeutic effect of table compares
Two groups of cure time comparison sheets 2 show that the external-applied ointment course for the treatment of of treatment exanthemv of the invention is significantly shorter than control Group does not find that external-applied ointment of the invention has any adverse reaction in therapeutic process.
2: two groups of healing time comparison sheets of table
Show that the external-applied ointment for treating exanthemv of the invention is significantly shorter than control by two groups of healing time comparison sheets Group does not find that external-applied ointment of the invention has any adverse reaction in therapeutic process.
The present invention carries out above-mentioned Chinese medicine fried in proportion, and ointment is then made for festering patient's external application, achieves fabulous Clinical effectiveness.Use clearing heat and detoxicating, expelling the stasis for the new for principle of reatment according to theory of traditional Chinese medical science, attack malicious method with nontoxic, through pair Thousands of patient clinicals use, efficient up to 99% or more, and cure rate is up to 93.34% or more, it is sufficient to illustrate clinical effectiveness.Among the above Medicine buying is convenient, and festering to treatment has peculiar effect, daily only to use 1-4 times, and general patient of festering suffers from use, applying outside Face can take effect, there is positive effect, excellent treatment effect in 5 days for 2 days.

Claims (5)

1. a kind of external-applied ointment for treating exanthemv, it is characterised in that the raw material including following parts by weight: Cortex Phellodendri 10-30, Huang Even 10-30 parts, 10-30 parts of rheum officinale, 5-20 parts of borneol, 10-200 parts of radix paeoniae rubra, 20-500 parts of Radix Salviae Miltiorrhizae, 20-60 parts of magnetite, gypsum 20-60 parts, 5-50 parts of dragon's blood, 20-100 parts of safron, 10-20 parts of beeswax, 10-30 parts of calamine, 30-50 parts of Radix Notoginseng.
2. a kind of external-applied ointment for treating exanthemv described in accordance with the claim 1, it is characterised in that also wrapped in the raw material Include 10-200 parts of honeysuckle, 5-15 parts of cow-bezoar.
3. a kind of external-applied ointment for treating exanthemv according to claim 1 or 2, it is characterised in that in the raw material also Raw material including following parts by weight: 20-100 parts of vaseline.
4. a kind of preparation process for the external-applied ointment for treating exanthemv, it is characterised in that the following steps are included:
1), take 10-30 parts of Cortex Phellodendri, 10-30 parts of the coptis, 10-30 parts of rheum officinale, 10-200 parts of radix paeoniae rubra, 20-500 parts of Radix Salviae Miltiorrhizae clean after Naturally dry；
2), above-mentioned Chinese medicine is ground to powdered, be placed in container, 80-300 parts of sesame oil are added into container；
3), container is placed in steamer, it is cool to set using moderate heat Steam by water bath 1.5-2.5 hours, filter out medical fluid；
4), 5-20 parts of borneols are added in 10-20 parts of beeswaxs, is placed in container and is melted using moderate heat Steam by water bath to beeswax；
5) medical fluid of step 4 is uniformly mixed with the mixture of step 5, pours into 10-30 parts of calamines, 20-60 parts of magnetic while hot Stone, 20-60 part gypsum, 30-50 portions of Radix Notoginseng, 20-100 parts of kumkums；
6), 5-50 parts of dragon's blood, 50-100 parts of ethyl alcohol are added in the resulting mixture of step 6 and are uniformly mixed；
7), it is cool but, close the lid preservation, to be installed, pending.
5. a kind of preparation process for the external-applied ointment for treating exanthemv according to claim 4, it is characterised in that described It further include 10-200 parts of honeysuckle, 5-15 parts of cow-bezoar in the raw material of step 1).
CN201910525112.1A 2019-06-18 2019-06-18 It is a kind of for treating the external-applied ointment and its preparation process of exanthemv Withdrawn CN110201078A (en)

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