CN103877151A - Egg butter traditional Chinese medicine ointment for treating oral ulcer - Google Patents
Egg butter traditional Chinese medicine ointment for treating oral ulcer Download PDFInfo
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- CN103877151A CN103877151A CN201410130400.4A CN201410130400A CN103877151A CN 103877151 A CN103877151 A CN 103877151A CN 201410130400 A CN201410130400 A CN 201410130400A CN 103877151 A CN103877151 A CN 103877151A
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Abstract
The invention discloses an egg butter traditional Chinese medicine ointment for treating oral ulcer. The egg-butter traditional Chinese medicine ointment comprises the following active ingredients by weight: 3-8g of cinnabaris, 3-8g of borneol, 2-4g of borax, 2-4g of endothelium corneum gigeriae galli, 1.5-2.5g of mint, 2-4g of alumen, 1.5-2.5g of indigo naturalis, and 4-6g of egg butter. In treatment, the egg butter traditional Chinese medicine ointment is coated or sprayed on the surface of the ulcer for four times per day, the egg butter traditional Chinese medicine ointment can relieve pain and diminish swelling after being sprayed for one to two times, and the mild ulcer can be basically healed for two to three days, so that the egg butter traditional Chinese medicine ointment is high in effect taking speed and high in cure rate. The formula is used by clinical 200 cases of patients with oral ulcer, the ulceration area can be fast reduced, the inflammation exudation can be lightened, pain symptoms can be alleviated, the disease courses can be obviously shortened, and no obvious toxic and side effects are discovered.
Description
Technical field
The present invention relates to a kind of Oleum Ovum Gallus domesticus Flavus Chinese medicinal ointment for the treatment of oral ulcer.
Background technology
Oral ulcer (qalulcer) is the damaged or depression of the local organization because of oral cavity or lingual mucous membrane epithelium, due to the slough disengaging of inflammatory necrosis tissue, and can involve the connective tissue of epithelium holostrome and below.The large I of ulcer is from the grain of rice to Semen Glycines size, rounded or oval, yellow-white, ulcer surface depression and congested around, obvious with normal mucosa boundary, can single-shot or multiple, clinical manifestation is that dispute is burnt, hurt like hell, especially attach most importance to the product of the pungent stimulation of taking food, while very talk, cause dispute unfavorable.Primary disease to be repeatedly to show effect, to delay difficulty more as feature, treats comparatively thornyly, treats mainly with watermelon crystal spray or the application of some antibiotic in the past, clinically takes effect slowly, and cure rate is low.
Summary of the invention
For above-mentioned prior art, the present invention provides a kind of Oleum Ovum Gallus domesticus Flavus Chinese medicinal ointment for the treatment of oral ulcer innovatively, it has nourishing blood and promoting granulation, removing toxic substances putrefaction removing, the more merit of skin ulcer of convergence, and curative effect is rather good clinically, has that curative effect is fast, side effect is little, cost is low, cure rate advantages of higher.
The present invention is achieved by the following technical solutions:
An Oleum Ovum Gallus domesticus Flavus Chinese medicinal ointment for the treatment of oral ulcer, is made up of following crude drug: 3~8 grams, Cinnabaris, 3~8 grams of Borneolum Syntheticums, 2~4 grams of Boraxs, 2~4 grams of Endothelium Corneum Gigeriae Galli, 1.5~2.5 grams of Herba Menthaes, 2~4 grams of Alumens, 1.5~2.5 grams of Indigo Naturaliss, 4~6 grams of Oleum Ovum Gallus domesticus Flavus.
Preferably, formed by following crude drug: 5 grams, Cinnabaris, 5 grams of Borneolum Syntheticums, 3 grams of Boraxs, 3 grams of Endothelium Corneum Gigeriae Galli, 2 grams of Herba Menthaes, 3 grams of Alumens, 2 grams of Indigo Naturaliss, 5 grams of Oleum Ovum Gallus domesticus Flavus.
The preparation method of the Oleum Ovum Gallus domesticus Flavus Chinese medicinal ointment of described treatment oral ulcer is: get Cinnabaris, Borneolum Syntheticum, Borax, Endothelium Corneum Gigeriae Galli, Herba Menthae, Alumen and Indigo Naturalis, after grinding, mix, mix with Oleum Ovum Gallus domesticus Flavus, mix, must treat the Oleum Ovum Gallus domesticus Flavus Chinese medicinal ointment of oral ulcer, bottling sealing, be for external application, when use, be overlying on affected part, or be applied to ulcer surface with cotton swab, every day 4 times, when serious symptom, can spray for several times.During application, should forbid irritable food, after medication, in several minutes, must not take food, drink water, the unsuitable prolonged application of this product.
The Oleum Ovum Gallus domesticus Flavus Chinese medicinal ointment for the treatment of oral ulcer of the present invention, is the prescription forming according to the characteristics of incidence of oral ulcer, and according to oral ulcer characteristics of incidence, Cinnabaris has calm removing toxic substances anticorrosion to affected part, can suppress or kill skin bacterium and parasite.The antiinflammatory of Borneolum Syntheticum pain relieving antiseptic and inhibiting bacteria function.Borax heat clearing away expectorant, detoxify anticorrosion.Endothelium Corneum Gigeriae Galli is containing gastric hormone, keratin, and promoting tissue regeneration and wound healing is controlled ulcer.Alumen has expectorant, dampness, hemostasis antiinflammatory.Herba Menthae wind-dispelling heat-dissipating, reduces inflammation and oozes out, and promotes the effect that ulcer surface absorbs.Indigo Naturalis heat clearing away, removing heat from blood, removing toxic substances.Oleum Ovum Gallus domesticus Flavus has sending down the abnormal ascending QI, effect of YIN nourishing, and among the people in order to treat the diarrhea and vomiting of the simple dyspepsia of children's, the present invention finds that it all has good removing the necrotic tissue and promoting granulation effect to mucosal ulcer, skin ulceration and tinea class.All medicine compatibilities, local application's successful, wind-dispelling heat-dissipating, remove the rotten and let fresh grow, rapid-action and side effect is little.When treatment, apply or be sprayed on ulcer surface, every day 4 times (can be coated with when serious symptom 6~8 times), general medication gets final product alleviating pain and detumescence 1~2 time, and light disease is almost recovered for 2~3 days, instant effect, and cure rate is high.This prescription uses through clinical more than 200 routine oral ulcer patients, can dwindle rapidly ulcer surface, reduce inflammation and ooze out, ease the pain symptom, obviously shortens the course of disease, does not find obvious toxic-side effects.
Described Oleum Ovum Gallus domesticus Flavus is existing raw material of Chinese medicine medicine in prior art, cooking eating method is: egg Fructus Forsythiae is boiled, shell breaking and albumen, stay egg yolk, put pot interior slow fire temper get oil (correct: if not fuel-displaced, not anti-trial is with vigorous fire, the egg yolk of taking scoop firmly to press to be partly charred or can be fuel-displaced).Attention: use is oil instead of the egg yolk after finishing here.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
The unguentum of embodiment 1 preparation treatment oral ulcer
Formula is: 5 grams, Cinnabaris, 5 grams of Borneolum Syntheticums, 3 grams of Boraxs, 3 grams of Endothelium Corneum Gigeriae Galli, 2 grams of Herba Menthaes, 3 grams of Alumens, 2 grams of Indigo Naturaliss, 5 grams of Oleum Ovum Gallus domesticus Flavus.
Preparation method is: get Cinnabaris, Borneolum Syntheticum, Borax, Endothelium Corneum Gigeriae Galli, Herba Menthae, Alumen and Indigo Naturalis, mix, mix with Oleum Ovum Gallus domesticus Flavus, mix, must treat the Oleum Ovum Gallus domesticus Flavus Chinese medicinal ointment of oral ulcer, bottling sealing, be for external application, when use, be overlying on affected part, or be applied to ulcer surface with cotton swab, every day 4 times, when serious symptom, can spray for several times.During application, should forbid irritable food, after medication, in several minutes, must not take food, drink water, the unsuitable prolonged application of this product.General medication gets final product alleviating pain and detumescence 1~2 time, and light disease is almost recovered for 2~3 days.
The Chinese medicinal ointment of embodiment 2 preparation treatment oral ulcer
Formula is: 3 grams, Cinnabaris, 8 grams of Borneolum Syntheticums, 2 grams of Boraxs, 4 grams of Endothelium Corneum Gigeriae Galli, 1.5 grams of Herba Menthaes, 4 grams of Alumens, 1.5 grams of Indigo Naturaliss, 6 grams of Oleum Ovum Gallus domesticus Flavus.
Preparation method and using method are with embodiment 1.
The Chinese medicinal ointment of embodiment 3 preparation treatment oral ulcer
Formula is: 8 grams, Cinnabaris, 3 grams of Borneolum Syntheticums, 4 grams of Boraxs, 2 grams of Endothelium Corneum Gigeriae Galli, 2.5 grams of Herba Menthaes, 2 grams of Alumens, 2.5 grams of Indigo Naturaliss, 4 grams of Oleum Ovum Gallus domesticus Flavus.
Preparation method and using method are with embodiment 1.
Clinical case data: treat altogether various oral pathology 168 examples from 2009 in Decembers, 12 to 2013, apply Drug therapy 88 examples of the present invention, separately treat 80 examples by control drug. now the observed result such as clinical efficacy, untoward reaction is reported as follows:
Case selection: patient's 168 examples, minimum 5 years old, maximum 65 years old, man's 81 examples, female's 87 examples, sick time 1~4 day, ulcer is single-shot or multiple, concentrates on 35 examples of lingual surface, is distributed in 80 examples of cheek, be distributed in 8 examples of gums, it is concurrent that remaining 45 examples are tongue, cheek, gums many places, and ulcer diameter is at 0.3~1.5cm, wherein 50 examples were once taken antimicrobial drug, Vc, B1, B2 etc., without other general disease.
Case grouping: adopt double blinding layering, randomized blocks, be divided into treatment group and matched group, treatment group 88 examples, matched group 80 examples.
Therapeutic Method: treatment group: the Chinese medicinal ointment treatment that adopts embodiment 1 to prepare, first cleaning oral cavity, ulcer place is directly coated with 1mm left and right coating with cotton swab, at least in 2h, does not drink water, and does not eat food, and gargles again, to extend drug effect as far as possible without clear water.Matched group adopts watermelon crystal spray, and its using method is the same, treats observe the curative effect after 3 days.
The standard of curative effect evaluation:
Recovery from illness: within a course for the treatment of, ulcer surface and pain disappear, it is normal that mucosa recovers.
Take a turn for the better: within a course for the treatment of, be clearly better, symptom obviously alleviates, and ulcer surface dwindles 70%.
Invalid: within a course for the treatment of, symptom is without improvement.
Result:
The harmony of data: two groups of Genders and the distribution situation at age, learn by statistics inspection there are no significant difference (p> 0.05), the formation that the sex and age of test group and matched group is described is thus balanced, has comparability.
Efficacy analysis: (1) treatment group: 88 examples, after treatment 3d, recovery from illness 80 examples (transference cure, ulcer healing); 7 examples that take a turn for the better (symptom obviously alleviates, and ulcer surface dwindles 70%); Invalid 1 example (symptom is without improving).After half a year, follow up a case by regular visits to, 86 examples do not recur, recurrence 2 examples.(2) matched group: 80 examples, after treatment 3d, recovery from illness 50 examples (transference cure, ulcer healing); 22 examples that take a turn for the better (symptom obviously alleviates, and ulcer surface dwindles 70%); Invalid 8 examples (symptom is without improving).After half a year, follow up a case by regular visits to, 70 examples do not recur, recurrence 10 examples.
Untoward reaction: all cases in test group and matched group are showed no the untoward reaction of local and whole body.
Discuss: 1, this medicine is effective Chinese medicinal ointment medicine of topical application treatment recurrent oral ulceration, and this side is the new formulation taking Oleum Ovum Gallus domesticus Flavus as Main Ingredients and Appearance.The treatment of the present invention to recurrent oral ulceration, shows through clinical research: Oleum Ovum Gallus domesticus Flavus Chinese medicinal ointment is treated above oral disease totally 88 examples, and total effective rate is 90.9%, illustrates that egg yolk ointment can obtain more satisfied curative effect to above oral disease.
2, in recurrent oral ulceration, observed pain, affected variation of feed situation, hyperemia and ulcer etc., all had significant difference compared with matched group, illustrated that Oleum Ovum Gallus domesticus Flavus Chinese medicinal ointment has the effects such as obvious antiinflammatory, hemostasis, pain relieving and promotion ulcer healing.
3, Oleum Ovum Gallus domesticus Flavus is the natural goods of artificial preparation, for nontoxic, non-stimulated, without anaphylactoid medicine.The present invention is doing also once to do stimulation oversaturation test (comprising skin and eye irritant test) before clinical research, and experimental result shows equal nonirritant, in this clinical verification research, does not also find whole body and local untoward reaction, is therefore easily accepted by doctor and patient.
Claims (3)
1. an Oleum Ovum Gallus domesticus Flavus Chinese medicinal ointment for the treatment of oral ulcer, is characterized in that: be made up of following crude drug: 3~8 grams, Cinnabaris, 3~8 grams of Borneolum Syntheticums, 2~4 grams of Boraxs, 2~4 grams of Endothelium Corneum Gigeriae Galli, 1.5~2.5 grams of Herba Menthaes, 2~4 grams of Alumens, 1.5~2.5 grams of Indigo Naturaliss, 4~6 grams of Oleum Ovum Gallus domesticus Flavus.
2. Oleum Ovum Gallus domesticus Flavus Chinese medicinal ointment according to claim 1, is characterized in that: be made up of following crude drug: 5 grams, Cinnabaris, 5 grams of Borneolum Syntheticums, 3 grams of Boraxs, 3 grams of Endothelium Corneum Gigeriae Galli, 2 grams of Herba Menthaes, 3 grams of Alumens, 2 grams of Indigo Naturaliss, 5 grams of Oleum Ovum Gallus domesticus Flavus.
3. the preparation method of the Oleum Ovum Gallus domesticus Flavus Chinese medicinal ointment described in claim 1,2, it is characterized in that: get Cinnabaris, Borneolum Syntheticum, Borax, Endothelium Corneum Gigeriae Galli, Herba Menthae, Alumen and Indigo Naturalis, mix, mix with Oleum Ovum Gallus domesticus Flavus, mix, must treat the Oleum Ovum Gallus domesticus Flavus Chinese medicinal ointment of oral ulcer.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104721233A (en) * | 2015-04-02 | 2015-06-24 | 屈喜 | Pharmaceutical preparation for treating heart diseases and cardiovascular diseases |
Citations (2)
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CN1207924A (en) * | 1998-08-07 | 1999-02-17 | 刘克贤 | Medicine for diseases of oral cavity, throat and gullet and its preparation |
CN101085045A (en) * | 2006-06-09 | 2007-12-12 | 方生洋 | Traditional Chinese medicine preparation for treating stomatitis |
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- 2014-04-02 CN CN201410130400.4A patent/CN103877151A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1207924A (en) * | 1998-08-07 | 1999-02-17 | 刘克贤 | Medicine for diseases of oral cavity, throat and gullet and its preparation |
CN101085045A (en) * | 2006-06-09 | 2007-12-12 | 方生洋 | Traditional Chinese medicine preparation for treating stomatitis |
Non-Patent Citations (2)
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张务良: "青冰矾散治疗口腔溃疡", 《山东中医杂志》 * |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104721233A (en) * | 2015-04-02 | 2015-06-24 | 屈喜 | Pharmaceutical preparation for treating heart diseases and cardiovascular diseases |
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Application publication date: 20140625 |