CN108785530A - A kind of liquefaction ointment for growing muscle and healing skin and preparation method thereof - Google Patents
A kind of liquefaction ointment for growing muscle and healing skin and preparation method thereof Download PDFInfo
- Publication number
- CN108785530A CN108785530A CN201810999828.0A CN201810999828A CN108785530A CN 108785530 A CN108785530 A CN 108785530A CN 201810999828 A CN201810999828 A CN 201810999828A CN 108785530 A CN108785530 A CN 108785530A
- Authority
- CN
- China
- Prior art keywords
- ointment
- liquefaction
- powder
- healing skin
- growing muscle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000002674 ointment Substances 0.000 title claims abstract description 51
- 230000035876 healing Effects 0.000 title claims abstract description 48
- 210000003205 muscle Anatomy 0.000 title claims abstract description 47
- 238000002360 preparation method Methods 0.000 title claims abstract description 21
- 239000000843 powder Substances 0.000 claims abstract description 44
- 239000003814 drug Substances 0.000 claims abstract description 41
- 235000019198 oils Nutrition 0.000 claims abstract description 24
- 239000004365 Protease Substances 0.000 claims abstract description 21
- 108010004032 Bromelains Proteins 0.000 claims abstract description 20
- 235000013871 bee wax Nutrition 0.000 claims abstract description 20
- 239000012166 beeswax Substances 0.000 claims abstract description 20
- 235000019835 bromelain Nutrition 0.000 claims abstract description 20
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 claims abstract description 14
- 235000006226 Areca catechu Nutrition 0.000 claims abstract description 14
- 244000025254 Cannabis sativa Species 0.000 claims abstract description 14
- 241001016465 Asplenium rhizophyllum Species 0.000 claims abstract description 13
- 240000003690 Callicarpa japonica Species 0.000 claims abstract description 13
- 235000017595 Callicarpa japonica Nutrition 0.000 claims abstract description 13
- 241000545744 Hirudinea Species 0.000 claims abstract description 13
- 229940099259 vaseline Drugs 0.000 claims abstract description 13
- 235000019484 Rapeseed oil Nutrition 0.000 claims abstract description 12
- 241001313857 Bletilla striata Species 0.000 claims abstract description 11
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 11
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 11
- 235000006040 Prunus persica var persica Nutrition 0.000 claims abstract description 11
- 240000003152 Rhus chinensis Species 0.000 claims abstract description 11
- 235000014220 Rhus chinensis Nutrition 0.000 claims abstract description 11
- NUJOXMJBOLGQSY-UHFFFAOYSA-N manganese dioxide Inorganic materials O=[Mn]=O NUJOXMJBOLGQSY-UHFFFAOYSA-N 0.000 claims abstract description 11
- 244000144730 Amygdalus persica Species 0.000 claims abstract description 9
- 244000080767 Areca catechu Species 0.000 claims abstract 4
- 239000003921 oil Substances 0.000 claims description 23
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 16
- 239000008158 vegetable oil Substances 0.000 claims description 16
- 244000235603 Acacia catechu Species 0.000 claims description 10
- 230000001114 myogenic effect Effects 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 239000002994 raw material Substances 0.000 claims description 3
- 239000002884 skin cream Substances 0.000 claims description 3
- 208000027418 Wounds and injury Diseases 0.000 abstract description 18
- 208000025865 Ulcer Diseases 0.000 abstract description 15
- 231100000397 ulcer Toxicity 0.000 abstract description 15
- 206010053615 Thermal burn Diseases 0.000 abstract description 11
- 210000003141 lower extremity Anatomy 0.000 abstract description 11
- 230000017531 blood circulation Effects 0.000 abstract description 9
- 210000001519 tissue Anatomy 0.000 abstract description 9
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 8
- 210000004369 blood Anatomy 0.000 abstract description 8
- 239000008280 blood Substances 0.000 abstract description 8
- 230000001737 promoting effect Effects 0.000 abstract description 8
- 208000004210 Pressure Ulcer Diseases 0.000 abstract description 5
- 206010047115 Vasculitis Diseases 0.000 abstract description 4
- 208000015181 infectious disease Diseases 0.000 abstract description 4
- 230000008961 swelling Effects 0.000 abstract description 4
- 206010012601 diabetes mellitus Diseases 0.000 abstract description 3
- 230000002980 postoperative effect Effects 0.000 abstract description 3
- 241000894006 Bacteria Species 0.000 abstract description 2
- 230000002155 anti-virotic effect Effects 0.000 abstract description 2
- 235000013372 meat Nutrition 0.000 abstract description 2
- 239000004615 ingredient Substances 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 description 16
- 230000000694 effects Effects 0.000 description 15
- 230000006870 function Effects 0.000 description 13
- 238000011282 treatment Methods 0.000 description 13
- 229940079593 drug Drugs 0.000 description 7
- 230000000144 pharmacologic effect Effects 0.000 description 7
- 239000006071 cream Substances 0.000 description 5
- 230000023597 hemostasis Effects 0.000 description 5
- 231100000241 scar Toxicity 0.000 description 5
- 238000001804 debridement Methods 0.000 description 4
- 238000011156 evaluation Methods 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 238000005469 granulation Methods 0.000 description 4
- 230000003179 granulation Effects 0.000 description 4
- 208000014674 injury Diseases 0.000 description 4
- 239000000546 pharmaceutical excipient Substances 0.000 description 4
- 201000004624 Dermatitis Diseases 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 3
- 206010019468 Hemiplegia Diseases 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 230000003115 biocidal effect Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000008733 trauma Effects 0.000 description 3
- 244000099147 Ananas comosus Species 0.000 description 2
- 235000007119 Ananas comosus Nutrition 0.000 description 2
- 241000256113 Culicidae Species 0.000 description 2
- 206010015150 Erythema Diseases 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 240000005809 Prunus persica Species 0.000 description 2
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- 208000007536 Thrombosis Diseases 0.000 description 2
- 206010053476 Traumatic haemorrhage Diseases 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000000202 analgesic effect Effects 0.000 description 2
- 230000002924 anti-infective effect Effects 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 208000010668 atopic eczema Diseases 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000003628 erosive effect Effects 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000017074 necrotic cell death Effects 0.000 description 2
- 239000011505 plaster Substances 0.000 description 2
- 239000000955 prescription drug Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 230000029663 wound healing Effects 0.000 description 2
- 239000005996 Blood meal Substances 0.000 description 1
- 206010008132 Cerebral thrombosis Diseases 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 208000032544 Cicatrix Diseases 0.000 description 1
- 206010012435 Dermatitis and eczema Diseases 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 201000001429 Intracranial Thrombosis Diseases 0.000 description 1
- 201000009053 Neurodermatitis Diseases 0.000 description 1
- 206010031252 Osteomyelitis Diseases 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 102000035195 Peptidases Human genes 0.000 description 1
- 206010039509 Scab Diseases 0.000 description 1
- 241000270295 Serpentes Species 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 206010072170 Skin wound Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000003402 anti-promotion Effects 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 229940030225 antihemorrhagics Drugs 0.000 description 1
- 239000003908 antipruritic agent Substances 0.000 description 1
- 230000004596 appetite loss Effects 0.000 description 1
- 206010003230 arteritis Diseases 0.000 description 1
- 230000005784 autoimmunity Effects 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000035568 catharsis Effects 0.000 description 1
- 230000003915 cell function Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 230000002279 cholagogic effect Effects 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000002951 depilatory effect Effects 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 230000003073 embolic effect Effects 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 231100000321 erythema Toxicity 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 210000003746 feather Anatomy 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 230000000025 haemostatic effect Effects 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 230000001976 improved effect Effects 0.000 description 1
- 230000002779 inactivation Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000011221 initial treatment Methods 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 235000021266 loss of appetite Nutrition 0.000 description 1
- 208000019017 loss of appetite Diseases 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000001151 other effect Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 208000001297 phlebitis Diseases 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000017854 proteolysis Effects 0.000 description 1
- 230000037387 scars Effects 0.000 description 1
- 108010048734 sclerotin Proteins 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 230000037314 wound repair Effects 0.000 description 1
- 239000009306 yunnan baiyao Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/32—Manganese; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/22—Cysteine endopeptidases (3.4.22)
- C12Y304/22004—Bromelain (3.4.22.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/35—Extraction with lipophilic solvents, e.g. Hexane or petrol ether
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Insects & Arthropods (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Wood Science & Technology (AREA)
- Animal Husbandry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Marine Sciences & Fisheries (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
Abstract
A kind of liquefaction ointment for growing muscle and healing skin, prescription are preferably:Rapeseed oil, and by based on rapeseed oil weight:Sibirica walking fern herb 3%, leech 4%, the bletilla striata 3%, Radix Notoginseng 3%, peach leaf 3%, Japanses beauty-berry grass 5%, Chinese gall 4%, pyrolusite powder 3%, catechu powder 3%, pearl powder 0.1%-0.6%, bromelain 0.1%-0.2%, beeswax 10%-25%, vaseline 3%.Preparation method is that the brewed rear small fire of the traditional Chinese medicine ingredients such as stirrup grass is added in rapeseed oil to be fried into yellow oil, then sequentially adds beeswax and vaseline and catechu powder while hot, pearl powder and bromelain forms.Suitable for body surface class sore caused by bacterium infection, always rotten lower limb, the rotten foot of diabetes, vasculitis, bedsore, burn and scald, postoperative incision not more and all ulcer, slough be de-, new meat is raw or long cannot the person of closing in, have the function of antibacterial antivirus, Conservative restoration be damaged cortex, promote blood circulation, impermeable surface wound deeply absorbs, is promoting blood circulation and removing blood stasis, swelling and pain relieving, promotion deep spoilage tissue voluntarily liquefy falls off and discharge pus slough etc..
Description
Technical field
The present invention relates to field of medical technology, specifically a kind of liquefaction ointment for growing muscle and healing skin and preparation method thereof.
Background technology
The illnesss such as are not more normal for various wounds and sore class (vasculitis, bedsore, ulcer on the shank), scalpel edge in people's life
See, not only incidence is high, but also degree difference is very big, and some conditions of the injury are serious and complicated, or even jeopardize the life of the wounded.Currently,
The drug for treating above-mentioned illness on the market has very much, but curative effect is different, and the drugs such as clinical common Yunnan Baiyao, burning hot cream all may be used
The wounded's slight illness, auxiliary wound healing, but wound of the existing drug for deep skin, wound can be mitigated to a certain extent
The therapeutic wound healings less effectives such as pyogenic infection, body surface chronic and refractory ulcer.Treat the common antibiotic of above-mentioned illness
Class drug, effect unobvious, and it is expensive, more important is larger side effect can be generated to patient.The side of western medical treatment
Method is typically to use debridement, disinfection, wrapping and operation, and the course for the treatment of is long, and healing is slow, costly, and is easy that there are scars more afterwards.
Invention content
To solve the above-mentioned problems, the present invention provides a kind of antibacterial antivirus with gain, Conservative restoration is damaged cortex, promotees
It is deeply absorbed into blood circulation, impermeable surface wound, promoting blood circulation and removing blood stasis, swelling and pain relieving, promotion deep spoilage tissue voluntarily liquefy and take off
It falls and discharges pus and the functions such as slough, and treatment course is short, the liquefaction ointment for growing muscle and healing skin and preparation method thereof of preventing from scar.
To achieve the goals above, the technical solution of use is as follows:
A kind of liquefaction ointment for growing muscle and healing skin, the prescription that is made for liquefying ointment for growing muscle and healing skin include:Vegetable oil, and by opposite
It is calculated in vegetable oil weight:Sibirica walking fern herb 2.8-3.2%, leech 3.7-4.3%, bletilla striata 2.8-3.2%, Radix Notoginseng 2.8-3.2%,
Peach leaf 2.8-3.2%, Japanses beauty-berry grass 4.5-5.5%, Chinese gall 3.7-4.3%, pyrolusite powder 2.8-3.2%, catechu powder 2.8-
3.2% (under rear), pearl powder 0.1%-0.6%, bromelain 0.1%-0.2%, beeswax 10%-25%, vaseline 2.8-
3.2%.
A kind of liquefaction ointment for growing muscle and healing skin as described above, the vegetable oil are rapeseed oil.
A kind of liquefaction ointment for growing muscle and healing skin as described above, the bromelain are 300,000 units.
A kind of liquefaction ointment for growing muscle and healing skin as described above, the prescription that is made for liquefying ointment for growing muscle and healing skin include:Vegetable oil,
And by calculating relative to vegetable oil weight:Sibirica walking fern herb 3%, leech 4%, the bletilla striata 3%, Radix Notoginseng 3%, peach leaf 3%, Japanses beauty-berry grass
5%, Chinese gall 4%, pyrolusite powder 3%, catechu powder 3%, pearl powder 0.1%-0.6%, bromelain 0.1%-0.2%,
Beeswax 10%-25%, vaseline 3%.
A kind of liquefaction ointment for growing muscle and healing skin as described above, by the beeswax 15%- calculated relative to vegetable oil weight
25%.
A kind of preparation method of above-mentioned liquefaction ointment for growing muscle and healing skin, the preparation method include the following steps:
The first step prepares raw material:
Sibirica walking fern herb, leech, the bletilla striata, Radix Notoginseng, peach leaf, Japanses beauty-berry grass, Chinese gall, pyrolusite powder is taken to immerse plant by set weight
In oil, place a couple of days, it is spare;
Second step, it is fried:
Ready medicine oil in the first step is taken, medicine oil is placed on fire, small fire is slow to decoct;
Third walks, fried completion:
The medicine oil of each Chinese medicine to be mixed decocts yellowly oil, then fried completion;
Beeswax and vaseline is added in 4th step:
The medicine oil that third step has been decocted is filtered into the dregs of a decoction, the beeswax and vaseline of set weight are added while hot, its whole is made to melt
Change;
5th step:Catechu powder, pearl powder and bromelain is added:
Before the medicine oil cooled and solidified that the 4th step obtains, catechu powder, pearl powder and the bromelain of set weight is added.
The preparation method of liquefaction ointment for growing muscle and healing skin as described above further includes:
6th step, it is filling:
It is carried out before the medicine oil cooling that the 5th step obtains filling.
The preparation method of liquefaction ointment for growing muscle and healing skin as described above, it is 7 days or more to place number of days in the first step.
The preparation method of liquefaction ointment for growing muscle and healing skin as described above, small fire is slow in the second step decoct during, often decoct one section
Time turns down the duration and degree of heating, then restores again, repeatedly several times.
The preparation method of liquefaction ointment for growing muscle and healing skin as described above, described is 2-6 times repeatedly several times repeatedly.
The beneficial effects of the invention are as follows:
The present invention is based on modern clinic experiences, are formed in conjunction with clinical practice and case research, first in inventive formulation
The pharmacological property and pharmacological effect for the every taste medicine being based on carry out as detailed below.
Sibirica walking fern herb, which has, improves autoimmunity, promoting blood circulation and removing blood stasis, hemostasis function of detoxification, primary treatment thrombosis-obstructive vessel
The illnesss such as inflammation, the ulcer of lower limb, hemiplegia, traumatic hemorrhage, neurodermatitis;Leech can improve local circulation, be conducive to nervous function
Recovery, can thrombus, have effects that dissipating blood stasis with potent drugs dredging collateral, metal-inflicted wound, blood vessel bolt disease such as phlebitis, occlusive can be treated
Vasculitis, embolic arteritis etc.;Bletilla striata energy astringing to arrest bleeding, detumescence and promoting granulation can treat traumatic hemorrhage, sore swollen toxin, scald etc.;
Radix Notoginseng has dissipate stasis of blood hemostasis, detumescence ding-tong, sore swell and ache curative, trauma hemostasis, disperse blood stasis and dredge collateral and other effects;Peach leaf is killed with wind-damp dispelling
Worm, clearing heat and detoxicating, eczema, sore are antipruritic, the functions such as inducing meastruation to relieve menalgia;Japanses beauty-berry grass has hemostasis, antibacterial action to trauma of spleen and wound,
Can anti-inflammatory analgetic, have preferable hemostasis work(to dog liver, trauma of spleen, bullet wound using Japanses beauty-berry grass extracting solution as No. 35 styptic powders of main ingredient
Energy;Chinese gall can prevent paddy-field dermatitis, treat cervical erosion, there is convergence antibacterial action;There is catechu promoting blood circulation and stopping pain, hygroscopic to hold back
Sore, myogenic control ulcer, the functions such as treatment skin eczema;Pyrolusite is relieved pain with stasis eliminatings, detumescence and promoting granulation, the main metal-inflicted wound function of ulcer on the shank;
Pearl powder can adjust endocrine, solve taking poison and growing muscle due, to knife wound, scald, burn, can quick-acting haemostatic powder, and it is fast to close up, and puts on flesh fast, disappears
It is scorching fast, and preventing from scar;Beeswax can detoxify, relieve pain, and have treatment burn and scald, myogenic sore pain inside fire attack burst for a long time and does not holds back, dermatitis and eczema etc.
Function can receive cream;Select the rape seed oil in vegetable oil, clearing liver cholagogic, anti-inflammatory skin care that can soften blood vessel.What the present invention selected
Above-mentioned Chinese medicine, is consistent inside and outside being pharmacologically particular about, and is particular about in effect and efficiently suits the medicine to the illness.
Bromelain is combined in the formula of the present invention, uses the principle of zymetology debridement, zymetology debridement is to use certain
A little exogenous enzymes with proteolysis remove the tissue breakdown of necrosis or inactivation, while not damaging normal group neighbouring
It knits.Due to the effect for the inhibiting factor that cell generates, these exogenous proteases usually will not generate hydrolysis to living tissue,
Necrosis or devitalized tissue are only decomposed, so as to play the role of the debridement with high selectivity in theory.Passing through pineapple egg
After the catharsis of white enzyme, liquefaction ointment for growing muscle and healing skin then can farthest transfer the immune system of body itself, and the surface of a wound is made to produce
The raw nutrient solution rich in immunocompetent cell and total local capilary for sticking active factors, can effectively adjust wound tissue cell
Function, to anti-infective and promotion organization healing.Various wounds are not cured, using different external therapys, the present invention attempts will be with
Relative to vegetable oil (rapeseed oil) weight meter, the bromelain of 0.1%-0.2% is added in liquefaction ointment for growing muscle and healing skin, " changes rotten
Method of reproduction " achieves preferable effect, promotes the immediate union of the surface of a wound, shortens the treatment time of patient.
Its scope of application of liquefaction ointment for growing muscle and healing skin of the present invention is:It is body surface class sore caused by bacterium infection, old rotten
The rotten foot of leg, diabetes, vasculitis, bedsore, burn and scald, postoperative incision are not cured.Not suitable for not de-, the new meat of all ulcer, slough
Or it long cannot the person of closing in when life.
Each taste prescription drug of the present invention is selected by clinical test for many years many times on the basis of theoretical research
Fixed, the dosage of each taste prescription drug is also gone through to be verified repeatedly, this makes its feature of the liquefaction ointment for growing muscle and healing skin of the present invention not be
Be limited to more to the ill, purposes is wide, but on the basis of fully having studied the general character of its targeted each indication mainly for
The breakthrough of drug effect, therefore it is totally different from all kinds of omnipotent plaster in the market, relative to plaster in the market, liquefaction of the invention
Ointment for growing muscle and healing skin more emphasizes the support of mechanism and the castering action of drug effect.
In summary it analyzes, liquefaction ointment for growing muscle and healing skin provided by the present invention, the following functions with gain:1, antibacterial to kill
Malicious function;2, Conservative restoration is damaged the function of cortex;3, promote the blood circulation in affected part;4, impermeable surface wound, deeply absorption
Function;5, promoting blood circulation and removing blood stasis, swelling and pain relieving function;6, promote deep spoilage tissue voluntarily liquefy fall off and discharge pus and
The function of slough.In addition, as another outstanding feature, liquefaction ointment for growing muscle and healing skin provided by the invention, treatment course is short, no
Stay scar.
Specific embodiment
The illustrative embodiments of the disclosure are described in more detail below.It is to be appreciated that providing these embodiments is
In order to be best understood from the disclosure, and the scope of the present disclosure can be completely communicated to those skilled in the art
Member, may be realized in various forms the disclosure, without should be limited by embodiments set forth herein.
Embodiment 1
A kind of liquefaction ointment for growing muscle and healing skin, the prescription that is made for liquefying ointment for growing muscle and healing skin include:Rapeseed oil, and by opposite
It is calculated in rapeseed oil weight:Sibirica walking fern herb 3%, leech 4%, the bletilla striata 3%, Radix Notoginseng 3%, peach leaf 3%, Japanses beauty-berry grass 5%, Chinese gall
4%, pyrolusite powder 3%, catechu powder 3% (under rear), pearl powder 0.1%-0.6%, bromelain 0.1%-0.2%, beeswax
15%-25%, vaseline 3%.
The preparation method of above-mentioned liquefaction ointment for growing muscle and healing skin, the preparation method include the following steps:
The first step prepares raw material:
Sibirica walking fern herb, leech, the bletilla striata, Radix Notoginseng, peach leaf, Japanses beauty-berry grass, Chinese gall, pyrolusite powder 8 are taken by the weight of above-mentioned determination
Kind Chinese medicine immerses in vegetable oil, place 7 days or more, it is spare;
Second step, it is fried:
Ready medicine oil in the first step is taken, medicine oil is placed on fire, small fire is slow to decoct, and has to here slow with minimum fire
It decocts, not paste, during which, often decoct a period of time, the duration and degree of heating is turned down, is then restored again, 2-6 times repeatedly, such as preferably repeatedly 4
It is secondary;
Third walks, fried completion:
The medicine oil of each Chinese medicines such as to be mixed sibirica walking fern herb, leech, Japanses beauty-berry grass decocts yellowly oil, then fried completion, here still
So it is noted that cannot paste, paste that can only just to outwell again feeding fried;
Beeswax and vaseline is added in 4th step:
The medicine oil that third step has been decocted is filtered into the dregs of a decoction, the beeswax and vaseline of above-mentioned determining weight are added while hot, keeps it complete
Melt in portion;
5th step:Catechu powder, pearl powder and bromelain is added:
Before the medicine oil cooled and solidified that the 4th step obtains, catechu powder, pearl powder and the pineapple egg of above-mentioned determining weight is added
White enzyme.
6th step, it is filling:
It is carried out before the medicine oil cooling that the 5th step obtains filling.
Embodiment 2
The present embodiment be for pearl powder, bromelain, beeswax dosage in embodiment 1 still more preferably, here
Still it presses and is calculated relative to rapeseed oil weight, pearl powder 0.3%, bromelain 0.1%, beeswax 20%;Alternatively, pearl powder
0.5%, bromelain 0.2%, beeswax 22%.In addition to this, other prescription dosages of the present embodiment and liquefaction life
The preparation method of muscle and healing skin cream is identical as having been described in embodiment 1.
Embodiment 3
A kind of liquefaction ointment for growing muscle and healing skin, the prescription that is made for liquefying ointment for growing muscle and healing skin include:Rapeseed oil, and by opposite
It is calculated in rapeseed oil weight:Sibirica walking fern herb 2.9%, leech 4.1%, the bletilla striata 2.9%, Radix Notoginseng 3.2%, peach leaf 2.9%, Japanses beauty-berry grass
5.2%, Chinese gall 3.8%, pyrolusite powder 3.1%, catechu powder 3.2% (under rear), pearl powder 0.2%, bromelain
0.1%, beeswax 20%, vaseline 2.9%.The preparation method of this liquefaction ointment for growing muscle and healing skin, it is in the same manner as in Example 1, it is no longer superfluous
It states.
The ointment for growing muscle and healing skin that liquefies described in various embodiments of the present invention can treat the rotten foot of always rotten lower limb, diabetes, osteomyelitis, cotton-padded mattress
Sore, postoperative incision be not cured, burn and scald etc., clinical that analysis and pharmacological evaluation are first carried out by taking burn and scald as an example.It is cured using Chinese medicine myogenic
Clinical 23 observation of curative effect of skin cream external-used burn and scald treating, for effective percentage up to 100%, cure rate does not stay scar up to 99% or more
Trace, short treating period is easy to use, obtains many patients and the approval of medical worker.Now such as by clinical analysis and pharmacological evaluation report
Under:
One, analysis
In 23, the oldest 55 years old, minimum 1 years old, male patient 14, female patient 9, maximum area of burning
Human body 25% is accounted for, minimum about 3% or so, course of disease longest 98 days is most 1 hour short, 7.7 days average, administration time longest 30 days, most
It is 2 days short, it is 16 days average.
Two, drug composition and dosage form
The sibirica walking fern herb of the effects that selecting anti-infective, promoting blood circulation and removing blood stasis, swelling and pain relieving, putrefaction-removing granulation-promoting, sore benefit skin, leech, three
The seven equal kinds of traditional Chinese medicines as described in the present embodiment 1, are improved using traditional ointment manufacture craft, are aided with the matrix of moisturizing, are made
The pure Chinese medicine external-use ointment for having the non-stimulated odorless of pitch sample gloss as a kind of yellow black, have resistance to evaporation, it is anti-it is dry and cracked without
The advantages that being easy to run off.
Three, pharmacological experimental method
Skin irritation test
1, reagent and drug:The second spring depilatory cream:The 9th pharmaceutical factory's product of Shanghai;Chinese medicinal ointment:The Juye clinics Yi Shoushen.
2, animal:The small domesticated dog of adult healthy, 5 kilograms of weight.
3, practice content and method:1. intact skin once daily skin irritatin;2. intact skin multiple dosing skin
Stimulation;3. damaged skin single administration skin irritatin;4. the stimulation of damaged skin multiple dosing.
4. result:Above-mentioned four experimental results observation does not occur erythema and oedema, by the scoring of skin wound repair
Scale is 0, nonirritant by skin irritatin intensity evaluation standard.
Animal scalds pharmacological action experiment
Experimental method:Healthy domesticated dog 5 is taken, back is lost hair or feathers 200cm2After 24 hours, domesticated dog is fixed, uses liquid wax
Constant temperature ----metal object is in direct contact 5 seconds, contact area 30*15cm at 200 ± 1 DEG C with dog skin2, every 4 pieces of domesticated dog scald,
And 4 groups are randomly divided into, it is confirmed as II ° of scald through pathological examination.
1. administration group:Apply Chinese medicinal ointment;2. positive control group:Apply snake oil;3. excipients group:Apply excipients;4. blank
Control group:It is without any processing.
Table 1:Experimental result
Group | Number of animals (only) | Scab forming time (day) |
Administration group | 5 | 8±0 |
Positive group | 5 | 10±4.4 |
Excipients group | 5 | 13±1.1 |
Blank control group | 5 | 13±1.2 |
The result shows that:For administration group compared with blank and excipients group, recovery from illness is very fast, and the positive is slightly faster than compared with positive group
Group.
Table 2:Bacteriostatic experiment result
Strain | Staphylococcus aureus | Pseudomonas aeruginosa | Escherichia coli |
Strain concentration | 0.049% | 0.049% | 0.049% |
Culture medium PH | 6.6 | 7.6 | 7.6 |
Antibacterial activity | ++ | + | - |
From the experimental results:The medicine has preferable antibacterial ability to staphylococcus aureus, also has antibacterial to Pseudomonas aeruginosa
Effect acts on unobvious to Escherichia coli.
Four, it summarizes
We are not cured using the various wounds of Chinese medicine ointment treatment burn, and by pharmacological evaluation and clinic trial, this cream is nontoxic
Side effect, treatment time is short, curative for effect.This medicine has infection control, convergence growing muscle and healing skin effect to the surface of a wound, is widely applying
In the case of antibiotic, drug resistance is generated quickly, and applies Chinese medicine myogenic paste, can reduce the side effect that Western medicine is brought, and
There is apparent analgesic effect, therefore traditional Chinese medicinal ointment is a kind of ideal medicament being worthy of promotion and application.
To further demonstrate that the clinical application of the present invention, some clinical cases are set forth below:
Bedsore model case
×× is opened, it is male, 70 years old, Juye supply and marketing cooperative retired cadre, in June, 2011 because apoplexy (cerebral thrombosis) enters county people
People hospital, through medical treatment sb.'s illness took a favorable turn stablize, there are the sequelae such as hemiplegia.Because of long-term bed, limitation of activity, in being admitted to hospital
Bedsore is formed after three months at coccyx, through with antibiotic effect unobvious, therefore leaves hospital and arrives here diagnosis and treatment.Symptom body disappeared at that time
Thin, sallow complexion is indigestion and loss of appetite, hemiplegia, has at sacrococcyx at the ulcer surface two of 8*3cm sizes, and edge is red and swollen, and there is sheet in centre
Adherency, color is dark dim, has thin fester to ooze out, and intermediate visible sclerotin is exposed, 38.9 DEG C of body temperature, with ointment for growing muscle and healing skin sliver to cotton-padded mattress
Sore deep is added medicine to, and by ointment ribbon gauze complete mulching sore face, wrapping, dressing once a day, the 6th, slough took off, and edge redness disappears
Lose, ulcer surface has the new granulation of pale red to grow, and local circumstance is good within the 9th day, and sore face is reduced into 4*2cm, after use this cream to be total to always
Treatment 20 days, sore face all healed.
Ulcer of lower limb model case
×× is opened, it is male, 81 years old, retired employees of brewery of county, first visit on April 23 in 2011.
Main suit:Right lower extremity ulcer 3 days.Medical history:Before 3 days, right lower extremity is scratched by bite by mosquitos, preceding right lower extremity by bite by mosquitos
Sore face constantly expands after broken, through multi-treatment, curative effect unobvious.Previously there is double lower limb varication history 11 years, checks right lower extremity
See the ulcer of 10cm*8cm at 1/3 under inside, sore covering weave canescence changes, and has downright bad sample tissue, with yellow diffusate,
Sore face is recessed, and notch is played on side, and the shallow erosion of ulcer surrounding skin table changes with pigmentation sample, and suffering limb has pitting edema.
Laboratory examination:Blood leukocytes 8.3*109/ L, neutrality 78%, empty stomach blood meal 5.21mmol/L.Diagnosis:Right lower extremity
Chronic ulcer.
With liquefaction ointment for growing muscle and healing skin after 3 dressings, sore face slough gradually falls off, and tissue gradually turns fresh and alive, and sees there is new life
Granulation is grown, and after continuing dressing 20 days, right lower extremity ulcer surface is obviously reduced, and only there are the sore faces of 3cm*2cm, continue dressing 45
It, sore face all healed and receive work(, with controlling more than 1 year no relapse.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto,
Any one skilled in the art in the technical scope disclosed by the present invention, the change or replacement that can be readily occurred in,
It should be covered by the protection scope of the present invention.Therefore, protection scope of the present invention should be with the protection model of the claim
Subject to enclosing.
Claims (10)
1. a kind of liquefaction ointment for growing muscle and healing skin, which is characterized in that it is described liquefaction ointment for growing muscle and healing skin the prescription that is made include:Vegetable oil,
And by calculating relative to vegetable oil weight:Sibirica walking fern herb 2.8-3.2%, leech 3.7-4.3%, bletilla striata 2.8-3.2%, Radix Notoginseng
2.8-3.2%, peach leaf 2.8-3.2%, Japanses beauty-berry grass 4.5-5.5%, Chinese gall 3.7-4.3%, pyrolusite powder 2.8-3.2%, youngster
Tea powder 2.8-3.2% (rear under), pearl powder 0.1%-0.6%, bromelain 0.1%-0.2%, beeswax 10%-25% are all
Intellectual circle 2.8-3.2%.
2. a kind of liquefaction ointment for growing muscle and healing skin according to claim 1, which is characterized in that the vegetable oil is rapeseed oil.
3. a kind of liquefaction ointment for growing muscle and healing skin according to claim 1, which is characterized in that the bromelain is 300,000 single
Position.
4. according to a kind of liquefaction ointment for growing muscle and healing skin of claim 1-3 any one of them, which is characterized in that the liquefaction myogenic is cured
The prescription that is made of skin cream includes:Vegetable oil, and by calculating relative to vegetable oil weight:Sibirica walking fern herb 3%, leech 4%, the bletilla striata
3%, Radix Notoginseng 3%, peach leaf 3%, Japanses beauty-berry grass 5%, Chinese gall 4%, pyrolusite powder 3%, catechu powder 3% (under rear), pearl powder
0.1%-0.6%, bromelain 0.1%-0.2%, beeswax 10%-25%, vaseline 3%.
5. a kind of liquefaction ointment for growing muscle and healing skin according to claim 4, which is characterized in that calculated by relative to vegetable oil weight
The beeswax be 15%-25%.
6. a kind of a kind of preparation method of liquefaction ointment for growing muscle and healing skin described in claim 1-5 any one, which is characterized in that institute
The preparation method stated includes the following steps:
The first step prepares raw material:
Sibirica walking fern herb, leech, the bletilla striata, Radix Notoginseng, peach leaf, Japanses beauty-berry grass, Chinese gall, pyrolusite powder is taken to immerse vegetable oil by set weight
In, it places a couple of days, it is spare;
Second step, it is fried:
Ready medicine oil in the first step is taken, medicine oil is placed on fire, small fire is slow to decoct;
Third walks, fried completion:
The medicine oil of each Chinese medicine to be mixed decocts yellowly oil, then fried completion;
Beeswax and vaseline is added in 4th step:
The medicine oil that third step has been decocted is filtered into the dregs of a decoction, the beeswax and vaseline of set weight are added while hot, it is made all to melt;
5th step:Catechu powder, pearl powder and bromelain is added:
Before the medicine oil cooled and solidified that the 4th step obtains, catechu powder, pearl powder and the bromelain of set weight is added.
7. the preparation method of liquefaction ointment for growing muscle and healing skin according to claim 6, which is characterized in that further include:
6th step, it is filling:
It is carried out before the medicine oil cooling that the 5th step obtains filling.
8. the preparation method of liquefaction ointment for growing muscle and healing skin according to claim 6, which is characterized in that placed in the first step
Number of days is 7 days or more.
9. the preparation method of liquefaction ointment for growing muscle and healing skin according to claim 6, which is characterized in that small fire in the second step
It is slow to decoct period, a period of time is often decocted, the duration and degree of heating is turned down, is then restored again, repeatedly several times.
10. the preparation method of liquefaction ointment for growing muscle and healing skin according to claim 9, which is characterized in that it is described repeatedly several times
It is 2-6 times repeatedly.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810999828.0A CN108785530A (en) | 2018-08-30 | 2018-08-30 | A kind of liquefaction ointment for growing muscle and healing skin and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810999828.0A CN108785530A (en) | 2018-08-30 | 2018-08-30 | A kind of liquefaction ointment for growing muscle and healing skin and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN108785530A true CN108785530A (en) | 2018-11-13 |
Family
ID=64081599
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810999828.0A Withdrawn CN108785530A (en) | 2018-08-30 | 2018-08-30 | A kind of liquefaction ointment for growing muscle and healing skin and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN108785530A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114558123A (en) * | 2020-12-20 | 2022-05-31 | 天津中医药大学第二附属医院 | Pharmaceutical composition for treating foot ulcer |
-
2018
- 2018-08-30 CN CN201810999828.0A patent/CN108785530A/en not_active Withdrawn
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114558123A (en) * | 2020-12-20 | 2022-05-31 | 天津中医药大学第二附属医院 | Pharmaceutical composition for treating foot ulcer |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US11571452B2 (en) | Method of treating a skin wound with a liquid-state topical pharmaceutical composition | |
CN101310748B (en) | Ointment for treating empyrosis | |
CN106728727A (en) | It is a kind of to treat ointment of sore and preparation method thereof | |
CN102366544A (en) | Bedsore ointment and preparation method thereof | |
CN110292602A (en) | Yellow burn oil formula of a kind of compound five and preparation method thereof | |
CN102357203B (en) | Cortex ulmis burn ointment for curing burns | |
CN103893557A (en) | Traditional Chinese medicine preparation for treating bedsore | |
CN108785530A (en) | A kind of liquefaction ointment for growing muscle and healing skin and preparation method thereof | |
CN101401890B (en) | External use medicament capable of effectively treating wound surface infection | |
CN102872244B (en) | Burn and scald treatment medicament and preparation method thereof | |
CN102698086B (en) | Chinese medicinal emulsion for treating bedsore accumulated toxin decay | |
CN111991471A (en) | A topical Chinese medicinal preparation for treating knife wound, burn and scald, and its preparation method | |
CN101036712A (en) | Scald and burn ointment | |
CN101703739B (en) | Chinese medicinal linimentum for treating trauma and traumatic infection | |
CN104147315A (en) | Emulsion medicine for treating scald and burn and preparation method thereof | |
CN110859902A (en) | Medicine for treating burn, scald and trauma | |
CN110384748A (en) | A kind of weapons wound badu shengji powder | |
CN110063992A (en) | Burn and scald medication and preparation method thereof | |
CN102178795B (en) | External medicine for treating burns and scalds and preparation method of medicine | |
CN106728069A (en) | It is a kind of to treat the putrefaction-removing granulation-promoting paste for scalding burn | |
CN101357153B (en) | No-scar medicine for treating burn and scald and preparation method thereof | |
CN115120656A (en) | Medicine for wound repair and preparation method thereof | |
CN113768993A (en) | A Chinese medicinal composition for treating soft tissue contusion such as burn, scald and bedsore, and its preparation method | |
CN104435730A (en) | Externally applied traditional Chinese medicine ointment for treating skin ulcer | |
CN116531460A (en) | Traditional Chinese medicine powder for treating huge bedsores and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WW01 | Invention patent application withdrawn after publication |
Application publication date: 20181113 |
|
WW01 | Invention patent application withdrawn after publication |