CN110200870A - A kind of reparation moisture retention water containing solanum lyratum and Flos Hibisci extract - Google Patents
A kind of reparation moisture retention water containing solanum lyratum and Flos Hibisci extract Download PDFInfo
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
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- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
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Abstract
The invention discloses a kind of reparation moisture retention water and preparation method thereof containing solanum lyratum and Flos Hibisci extract, the reparation moisture retention water contain white hair boisiana extract, Flos Hibisci extract, propylene glycol, glycerol, beta glucan, allantoin, water-soluble jojoba oil, disodium ethylene diamine tetraacetate, citric acid, Phenoxyethanol, deionized water.Functional component extracts gained by solanum lyratum, shrub althea flower.Reparation moisture retention water provided by the invention containing solanum lyratum and Flos Hibisci extract, have certain moisturizing, repair skin barrier, anti-oxidant, antibacterial and other effects；Simple production process of the present invention simultaneously, after smearing without thick and heavy greasy feeling, be easy to absorb, moisturizing water lock works well, and moistens the long-acting water of skin.The white hair boisiana extract of use, Flos Hibisci extract bioactivity are good, mild non-stimulated.
Description
Technical field
The invention belongs to the technical fields of cosmetics, and in particular to a kind of reparation guarantor containing solanum lyratum and Flos Hibisci extract
Wet water.
Background technique
Skin is located at body surface outermost layer, has barrier, absorption, secretion, excretion, metabolism, immune, body heat regulation and sense
Feel function, wherein skin barrier (skin barrier) function is basis.Nineteen eighty-three California, USA university Peter
The structure and function of Damages of Epidermal Permeability Barrier is described in detail in M.Elias professor (skin brick wall structure founder), proposes to be located at skin
The outermost cuticula of skin plays the role of important Damages of Epidermal Permeability Barrier, and image describes it as " brick wall structure ", i.e. angle
Horn cell in matter layer constitutes the brick in " brick wall structure "；Intercellular lipid then constitutes the mortar in " brick wall structure ", angle
This in matter layer by horn cell is mixed in the complex laminate film structure that intercellular lipid is constituted, and to maintain us normal
Damages of Epidermal Permeability Barrier function.The invasion that antigenic substance, microorganism, daylight etc. can externally be resisted, can internally prevent endotrophic
The loss of substance, moisture.Damages of Epidermal Permeability Barrier is impaired, be lost through transepidermal water (transepidermal waterloss,
TEWL) increase, drying, furfur, aging, pigmentation, atopic dermatitis, eczema, psoriasis, ichthyosis, day then occurs in skin
The skin greasings such as the skin sensitivities such as photosensitiveness dermatitis, irritant dermatitis, steroid dependent dermatitis, seborrhea disease, as acne,
Acne rosacea, seborrhea.Meanwhile the resilience of external antigen and microorganism is declined, it can lead to the hair of multiple dermatosis
It is raw.Damages of Epidermal Permeability Barrier and immunization barrier, acid barrier and Tiny ecosystem collectively form a total defense system.The micro- life of epidermis
State, pH value can influence Damages of Epidermal Permeability Barrier, and Damages of Epidermal Permeability Barrier is impaired, and can influence other barrier functions.
With the improvement of living standards, people also increasingly focus on the maintenance of skin, however the environment such as ultraviolet radioactive influence
And the reasons such as body intracellular metabolite is slow, imbalance lead to various skin problems.It is pointed out according to dermatologist, the moisture in baby
80% or more of percentage of liveweight, and intracorporal moisture can successively decrease with the age, since baby has enough moisture, skin can be shown
Obtain careful gloss.In fact, adult has enough sebum secretions, but the moisture content of skin of adult female only has 65% or lower
(wherein cutin only 15%), well below cradle, therefore, water shortage is the root of all skin problems.
Moisture evaporation is three reasons nothing but: the moisture of high temperature, drying and strong wind, skin is no exception.Therefore, a Nian Si
The climate characteristic in season all more or less contains these factors, so requiring replenishing water and preserving moisture throughout the year.Three above is former
Because only environmental factor, skin are lost the problem of moisture further includes skin itself.In addition to this, urban life pressure is big, fatigue,
Work overtime, stay up late, diet it is unreasonable, aggravated the water shortage status of skin.Skin can seem delicate because sufficient moisture content is possessed
Smooth, skin water shortage will lead to dry, jaundice, intensely dark pool, the aging phenomenons such as relaxation, wrinkle, and be easy to tighten, can also be
Now and nose branch shows microgroove.Modern life rhythm is fast simultaneously, and work is worked hard, therefore is badly in need of a kind of easy to use, effective
Skin moisture retention water is to meet the needs of people.Which kind of, however, either approach to give skin moisturizing by, all it is very easy to be evaporated to
In air, and grease is best moisturizing ingredient, can keep skin moisture and not be lost.
In skin care field, replenishing water and preserving moisture is all the time constant topic, how to carry out replenishing water and preserving moisture, is protection skin
Matter of utmost importance.Moisture retention water is many kinds of currently on the market, but replenishing water and preserving moisture effect is not fully up to expectations, most alcohol content
It is higher, and irritation is larger, is not suitable for long-term use.Vegetable fat is different from animal fat, most plants grease in this respect
Liquid, and the substances such as the internal unsaturated fatty acid contained of most plants oil and microelement, vitamin E are in room temperature,
Naturally there are anti-oxidation characteristics.Meanwhile phytochemicals production is mild, do not stimulate, meets most colonial needs, a large amount of clinic is ground
Study carefully and also shows the diversity of natural product active ingredient, tolerance and more more superior than synthetic to the safety of skin
Property.Therefore, in terms of global cosmetics in recent years development trend, ascendant trend is presented in natural cosmetics temperature, this is to natural makeup
Product bring opportunity.
Solanum lyratum Solanum lyratum Thunb is perennial tendril draft, belongs to Solanaceae nightshade, medicinal history
It is long.The compound isolated from solanum lyratum has soaping agents, organic acid, terpene, Polyphenols, flavonoids, sterols, tonka-bean
Plain class, polysaccharide and other kinds of compound.Steroid alkaloid and saponin(e contained therein has antibacterial activity, wherein tomato
The effect of alkali is stronger, has anti-inflammatory, antiallergy, antipruritic and immunosuppressive action.2001, Wei-Wen Kuo etc. was white in research
The inoxidizability of the crude extract protection epidermal cell of English, the results showed that bittersweet crude extract can remove DPPH, can also postpone agent
The oxidation of dependence low-density lipoprotein is measured, colleague also reduces OxLDL ELISA induction and generates reactive oxygen species, subtracts
The expression of endothelium oxidation protein enzyme is lacked.
Rose of Sharon Hibiscussyriacus belongs to high mallow Hibiscus, machaka or dungarunga.It is a kind of filling that flower garden is common
The wooden seeds of flowering plants is distributed widely in China tropical and subtropical zone area.Shrub althea flower is viscous containing vegetable fat, essential amino acid, polysaccharide, polyalcohol
Liquid matter has the function of moisturizing and anti-oxidant, removing free radical.The total phenol and general flavone content highest of shrub althea flower original seed, antioxygen
The property changed is most strong.The paper " Primary Study of shrub althea flower bioactivity " of Jin Yueting etc. shows that 1g shrub althea flower is equivalent to 5.19mg dimension
Raw element C, there is the ability for removing DPPH；And its oxidation resistance is equivalent to 9.12mg vitamin C.Shrub althea flower extracting solution to bacterium and
Mould has certain inhibiting effect, and is significantly greater than mould to the inhibiting effect of bacterium.Its root skin have cyclic annular peptide,
Procyanidine, therefore equally there is sterilizing effect.This civil useful flower juice washes one's face the custom of beauty.Add in shrub althea flower juice
Add qs glycerin and emulsifier, vitamin E etc., be made into oil-in-water type (O/W) shin moisturizer, is suitable for neutral skin and uses, it is especially right
Person in middle and old age have senile plaque on hand, and person has certain effect of dispelling spots, while playing the effect of lubricating moisturizing again, compensates for common skin care
The insufficient defect of liquid biological active matter ingredient and microelement.The procyanidine contained in shrub althea flower can be in scavenger-cell film
Water-soluble and fat-soluble free radical, therefore, it is suppressed that discharge the process that certain enzymes remove injury capillary wall.Procyanidine connects
It connects on collagen, those can be prevented to destroy the harm of the enzyme of collagen.Procyanidine not only helps collagen fine
Dimension forms cross-linked structure, and can help the damage being excessively crosslinked caused by restoring because of injured and free radical.Excessively crosslinking
Connective tissue can be made to suffocate and hardening, so that skin be made to corrugate and premature aging.Anthocyanidin also protects human body to hurt from sunlight
Evil promotes to cure psoriasis and senile plaque.Procyanidine is also the fabulous additive of the skin cream of local application.Skin can be made young
Change, health, cell are dynamic, can restore its extensibility and elasticity, repair skin.
, there are many antiallergics and repairs skin care item, mainly there is anti-allergic skin care product in the phenomenon that for skin sensitivity water shortage, main
It will be by reducing the stimulation components such as fragrance, pigment, alcohol and preservative, or addition extract solution from aloe, chamomile extract liquor etc.
Raw material reaches antianaphylactic effect；In addition, there is addition hormone, skin can be played centainly after sensitivity phenomenon occurs for skin
Repair.It can be seen from the above, the single effect of existing skin care item, antiallergic and maintenance cannot be reached by being directed to sensitive skin
Double effects, and repairing efficiency is long；Even dependence is generated to containing hormone product.
106236696 B of Chinese patent application CN (application number 201610744048.2) discloses one kind and contains chlorophyll
Shu Min moisture retention water and preparation method thereof.But the problems such as and extraction process unstable there are chlorophyll is cumbersome, effect need to be investigated.
Chinese patent application CN102000011A (application number CN201010561334) discloses a kind of shrub althea flower lotion and its preparation
Method.But its extraction process there are extracting solution it is impure it is more, extraction efficiency is low.Through retrieving, it is not yet found that white hair boisiana extract
With the application of the compound of Flos Hibisci extract in moisturizing cosmetic.
Due to being mixed with a variety of organic compounds in the crude extract of natural products, and bioactivity content is low, unstable, separation
Purifying difficulty is big, and for the plant containing saponins, common water extraction is easy to make its decomposition, and is filtered under diminished pressure and will appear greatly
Measure foam, it is difficult to be concentrated, it is therefore desirable to more efficient purification process, to obtain pure extract.
Summary of the invention
To solve the above-mentioned problems, the present invention provides a kind of reparation moisture retention water containing solanum lyratum, Flos Hibisci extract,
Mild pro-skin easily absorbs, and safe and non-stimulating, moisturizing, Shu Min effect are good, and stable system.
The purpose of the present invention is what is be achieved through the following technical solutions:
A kind of reparation moisture retention water containing solanum lyratum and Flos Hibisci extract, is made of following components in parts by weight:
Further, the white hair boisiana extract the preparation method is as follows:
(1) it weighs a certain amount of solanum lyratum and cleans and dry, clayed into power, cross 60 meshes and obtain climbing nightshade, weigh
20~50 parts by weight；
(2) it disperses climbing nightshade in deionized water, stirring is sufficiently mixed to obtain solanum lyratum suspension；Climbing nightshade
Mass ratio with deionized water is 1:10~20；
(3) heating solanum lyratum suspension is subsequently added into 1.0-1.5 part by weight of cellulose enzyme to 40~55 DEG C, stirs, sufficiently
React 2-3h；
(4) pectase of 0.6-1.2 parts by weight, stirring, sufficiently reaction 1-2h are added in the mixed solution of step (3)；
(5) step (4) mixed solution reduces temperature to 35~50 DEG C, adjusts pH to 4~5 with pH adjusting agent, filters, removes
Filter residue；
(6) 120-150 parts by weight are concentrated the filtrate to get white hair boisiana extract.
Further, the Flos Hibisci extract the preparation method is as follows:
A1, by the fresh shrub althea flower just picked clean drain, its petal is separated, then its low temperature is lyophilized；
A2, the shrub althea flower after the drying of 20~40 parts by weight is weighed, is blended into powder, crosses 40 meshes, obtain rose of Sharon pollen
End；
A3, the deionized water that 3 times of weight of shrub althea flower powder are added are impregnated, and are added pH adjusting agent tune pH to 4, are added 0.5~1 weight
Part cellulase, is sufficiently stirred, sets 1.5h in 40~50 DEG C of waters bath with thermostatic control, adds the mass concentration of 5 times of weight of shrub althea flower powder to be
75% ethanol solution 1~2h of refluxing extraction, filters while hot, obtains first time extracting solution and the dregs of a decoction；
A4, ethanol solution 0.5~1h of refluxing extraction that the mass concentration of 5 times of weight of dosing slag is 50% into the dregs of a decoction, take advantage of
Heat filtering obtains second of extracting solution；
A5, first time extracting solution and second of extracting solution being mixed, ethyl alcohol is recycled in evaporation, and centrifugation takes supernatant liquor to use,
Extracting n-butyl alcohol 3 times, volatilize n-butanol, obtains Flos Hibisci extract.
Further, the pH adjusting agent is the hydrochloric acid solution of 2.5mol/L.
The preparation method for repairing moisture retention water containing solanum lyratum and Flos Hibisci extract that the invention also includes a kind of, including it is following
Step:
S1, propylene glycol, glycerol, beta glucan, allantoin, water-soluble jojoba oil, citric acid are added in deionized water
And disodium ethylene diamine tetraacetate, and 70~80 DEG C, under keeping warm mode are heated to, 20~30min of stirring obtains material A to uniform；
S2, material A is cooled to 30~40 DEG C, Phenoxyethanol, white hair boisiana extract and Flos Hibisci extract is added, continued
It is stirred until homogeneous, obtains material B；
S3, material B are cooled to -5~-10 DEG C, and after keeping the temperature 30~60min, filtering, final pasteurising repairs moisture retention water to obtain the final product.
Beneficial effects of the present invention:
1. the present invention uses natural plants, nutrition and pharmacology double action are had concurrently, it is hormone-free, without nocuousness such as heavy metals
Ingredient meets the long-acting requirement with addition natural component of cosmetics without any toxicity and side effects.
2. white hair boisiana extract has anti-oxidant, anti-inflammatory, antibacterial, antiallergic and other effects；Shrub althea flower is containing procyanidine etc. simultaneously
Flavone compound and polysaccharide have moisture-keeping function, can effectively facilitate blood circulation, lighten the stain, and nutrition skin increases skin
Skin elasticity, and there is radiation-resisting functional.
3. the present invention has moisturizing, locks skin moisture, Cucumber Extract, antibacterial is anti-inflammatory, antiallergic, repairs the effect of skin,
And skin is not stimulated mildly.
4. moderate cost of the present invention is suitble to various types skin to use.Especially sensitive skin and skin barrier are impaired
Skin.
5. the method for the present invention is simple, easy to implement；It, can be in certain journey under low temperature using enzyme extraction method and freeze drying technology
On degree, bioactivity is kept, prevents from being lost, improves yield and effect, refining effect is good, solves bioactive ingredients and is adding
The problem of inactivation is easily decomposed during work.Using enzyme extraction method, reaction is mild.
Specific embodiment
In order to better understand the present invention, below by embodiment to the present invention into further explanation, embodiment is served only for
It explains the present invention, any restriction can't be constituted to the present invention.
The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention..Unless otherwise specified, embodiment
Used in the conventional means that are well known to those skilled in the art of technological means, raw materials used is commercial goods.
Embodiment 1
1) it is formulated
A kind of reparation moisture retention water containing solanum lyratum, Flos Hibisci extract is grouped as by the group of following parts by weight:
Solanum lyratum extracting solution: 10 parts；Shrub althea flower extracting solution: 10 parts；Propylene glycol: 1 part；Glycerol: 2 parts；Beta glucan: 1 part；
Allantoin: 1 part；Water-soluble jojoba oil: 0.3 part；EDETATE SODIUM: 0.0008 part；Citric acid: 0.3 part；0.2 part of Phenoxyethanol；
74.1992 parts of deionized water.
2) it prepares
The white hair boisiana extract, is prepared in accordance with the following methods:
(1) solanum lyratum is cleaned and dries, and is clayed into power, and crosses 60 meshes and obtains climbing nightshade, weighs 20 parts by weight；
(2) it disperses climbing nightshade in deionized water, stirring is sufficiently mixed to obtain solanum lyratum suspension；Climbing nightshade
Mass ratio with deionized water is 1:10；
(3) heating solanum lyratum suspension is subsequently added into 1.0 part by weight of cellulose enzymes to 40 DEG C, stirs, sufficiently reaction 2h；
(4) pectase of 0.6 parts by weight is added in the mixed solution of step (3), stirs, sufficiently reaction 1h；
(5) step (4) mixed solution reduces temperature to 35 DEG C, and with the salt acid for adjusting pH of 2.5mol/L to 4~5, filtering is removed
Remove filter residue；
(6) 120 parts by weight are concentrated the filtrate to get white hair boisiana extract.
The Flos Hibisci extract the preparation method is as follows:
(1) the fresh shrub althea flower just picked is cleaned and drains, its petal is separated, then its low temperature is lyophilized；
(2) shrub althea flower after weighing the drying of 20 parts by weight puts it into pulper and blends into powder, crosses 40 meshes, obtain wood
Rose of Sharon pollen end；
(3) deionized water that 3 times of weight of shrub althea flower powder are added is impregnated, and is added 2.5mol/L hydrochloric acid tune pH to 4, is added 0.5 weight
Part cellulase is measured, is sufficiently stirred, sets 1.5h in 40 DEG C of waters bath with thermostatic control, adding 5 times of mass concentrations of shrub althea flower powder is 75% second
Alcoholic solution refluxing extraction 1h, is filtered while hot, obtains first time extracting solution and the dregs of a decoction；
(4) into the dregs of a decoction, the mass concentration of 5 times of weight of dosing slag is 50% ethanol solution refluxing extraction 0.5h, while hot mistake
Filter, obtains second of extracting solution；
(5) first time extracting solution and second of extracting solution are mixed, ethyl alcohol is recycled in Rotary Evaporators evaporation, and centrifugation takes
Layer clear liquid is used, and extracting n-butyl alcohol 3 times, volatilize n-butanol, obtains Flos Hibisci extract.
The reparation moisture retention water containing solanum lyratum, Flos Hibisci extract, is prepared in accordance with the following methods:
(1) propylene glycol, glycerol, beta glucan, allantoin, water-soluble jojoba oil, citric acid are added in deionized water
And disodium ethylene diamine tetraacetate, and 70 DEG C, under keeping warm mode are heated to, stirring 20min obtains material A to uniform；
(2) material A is cooled to 30 DEG C, Phenoxyethanol, white hair boisiana extract and Flos Hibisci extract is added, continues to stir
To uniform, material B is obtained；
(3) material B is cooled to -5 DEG C, and after keeping the temperature 30min, filtering, final pasteurising repairs moisture retention water to obtain the final product.
Embodiment 2
1) it is formulated
A kind of reparation moisture retention water containing solanum lyratum, Flos Hibisci extract is grouped as by the group of following parts by weight:
Solanum lyratum extracting solution: 15 parts；Shrub althea flower extracting solution: 20 parts；Propylene glycol: 2 parts；Glycerol: 2 parts；Beta glucan: 1 part；
Allantoin: 1 part；Water-soluble jojoba oil: 0.3 part；EDETATE SODIUM: 0.002 part；Citric acid: 1 part；0.2 part of Phenoxyethanol；It goes
57.498 parts of ionized water.
2) it prepares
The white hair boisiana extract, is prepared in accordance with the following methods:
(1) it weighs solanum lyratum and cleans and dry, clayed into power, cross 60 meshes and obtain climbing nightshade, weigh 20~50 weights
Measure part；
(2) it disperses climbing nightshade in deionized water, stirring is sufficiently mixed to obtain solanum lyratum suspension；Climbing nightshade
Mass ratio with deionized water is 1:10~1:20.；
(3) heating solanum lyratum suspension is subsequently added into 1.0-1.5 part by weight of cellulose enzyme to 40~55 DEG C, stirs, sufficiently
React 2-3h；
(4) pectase of 1.2 parts by weight is added in the mixed solution of step (3), stirs, sufficiently reaction 1-2h；
(5) step (4) mixed solution reduces temperature to 35~50 DEG C, with the salt acid for adjusting pH of 2.5mol/L to 4~5, mistake
Filter removes filter residue；
(6) 150 parts by weight are concentrated the filtrate to get white hair boisiana extract.
The Flos Hibisci extract the preparation method is as follows:
(1) the fresh shrub althea flower just picked is cleaned and drains, its petal is separated, then its low temperature is lyophilized；
(2) shrub althea flower after weighing the drying of 40 parts by weight puts it into pulper and blends into powder, crosses 40 meshes, obtain wood
Rose of Sharon pollen end；
(3) deionized water that 3 times of weight of shrub althea flower powder are added is impregnated, and is added 2.5mol/L hydrochloric acid tune pH to 4, is added 1 weight
Part cellulase, is sufficiently stirred, sets 1.5h in 40~50 DEG C of waters bath with thermostatic control, and adding 5 times of mass concentrations of shrub althea flower powder is 75%
Ethanol solution refluxing extraction 1h, is filtered while hot, obtains first time extracting solution and the dregs of a decoction；
(4) into the dregs of a decoction, the mass concentration of 5 times of weight of dosing slag is 50% ethanol solution refluxing extraction 1h, while hot mistake
Filter, obtains second of extracting solution；
(5) filtrate merges twice, Rotary Evaporators evaporation, recycles ethyl alcohol, and centrifugation takes supernatant liquor to use, extracting n-butyl alcohol 3
Secondary, volatilize n-butanol, obtains Flos Hibisci extract.
The reparation moisture retention water containing solanum lyratum, Flos Hibisci extract, is prepared in accordance with the following methods:
(1) propylene glycol, glycerol, beta glucan, allantoin, water-soluble jojoba oil, citric acid are added in deionized water
And disodium ethylene diamine tetraacetate, and 80 DEG C, under keeping warm mode are heated to, stirring 30min obtains material A to uniform；
(2) material A is cooled to 40 DEG C, Phenoxyethanol, white hair boisiana extract and Flos Hibisci extract is added, continues to stir
To uniform, material B is obtained；
(3) material B is cooled to -5~-10 DEG C, and after keeping the temperature 60min, filtering, final pasteurising repairs moisture retention water to obtain the final product.
Embodiment 3
1) it is formulated
A kind of reparation moisture retention water containing solanum lyratum, Flos Hibisci extract is grouped as by the group of following parts by weight:
Solanum lyratum extracting solution: 15 parts；Shrub althea flower extracting solution: 25 parts；Propylene glycol: 3 parts；Glycerol: 1 part；Beta glucan: 1 part；
Allantoin: 2 parts；Water-soluble jojoba oil: 0.4 part；EDETATE SODIUM: 0.003 part；Citric acid: 2 parts；0.2 part of Phenoxyethanol；It goes
54.498 parts of ionized water.
2) it prepares
The white hair boisiana extract, is prepared in accordance with the following methods:
(1) it weighs solanum lyratum and cleans and dry, clayed into power, cross 60 meshes and obtain climbing nightshade, weigh 20~50 weights
Measure part；
(2) it disperses climbing nightshade in deionized water, stirring is sufficiently mixed to obtain solanum lyratum suspension；Climbing nightshade
Mass ratio with deionized water is 1:10~1:20；
(3) heating solanum lyratum suspension is subsequently added into 1.0-1.5 part by weight of cellulose enzyme to 40~55 DEG C, stirs, sufficiently
React 2-3h；
(4) pectase of 1.2 parts by weight is added in the mixed solution of step (3), stirs, sufficiently reaction 1-2h；
(5) step (4) mixed solution reduces temperature to 35~50 DEG C, with the salt acid for adjusting pH of 2.5mol/L to 4~5, mistake
Filter removes filter residue；
(6) 150 parts by weight are concentrated the filtrate to get white hair boisiana extract.
The Flos Hibisci extract the preparation method is as follows:
(1) the fresh shrub althea flower just picked is cleaned and drains, its petal is separated, then its low temperature is lyophilized；
(2) shrub althea flower after weighing the drying of 40 parts by weight puts it into pulper and blends into powder, crosses 40 meshes, obtain wood
Rose of Sharon pollen end；
(3) deionized water that 3 times of weight of shrub althea flower powder are added is impregnated, and is added 2.5mol/L hydrochloric acid tune pH to 4, is added 1 weight
Part cellulase, is sufficiently stirred, sets 1.5h in 40~50 DEG C of waters bath with thermostatic control, and adding 5 times of mass concentrations of shrub althea flower powder is 75%
Ethanol solution refluxing extraction 1h, is filtered while hot, obtains first time extracting solution and the dregs of a decoction；
(4) into the dregs of a decoction, the mass concentration of 5 times of weight of dosing slag is 50% ethanol solution refluxing extraction 1h, while hot mistake
Filter, obtains second of extracting solution；
(5) filtrate merges twice, Rotary Evaporators evaporation, recycles ethyl alcohol, and centrifugation takes supernatant liquor to use, extracting n-butyl alcohol 3
Secondary, volatilize n-butanol, obtains Flos Hibisci extract.
The reparation moisture retention water containing solanum lyratum, Flos Hibisci extract, is prepared in accordance with the following methods:
(1) propylene glycol, glycerol, beta glucan, allantoin, water-soluble jojoba oil, citric acid are added in deionized water
And disodium ethylene diamine tetraacetate, and 80 DEG C, under keeping warm mode are heated to, stirring 30min obtains material A to uniform；
(2) material A is cooled to 40 DEG C, Phenoxyethanol, white hair boisiana extract and Flos Hibisci extract is added, continues to stir
To uniform, material B is obtained；
(3) material B is cooled to -5~-10 DEG C, and after keeping the temperature 60min, filtering, final pasteurising repairs moisture retention water to obtain the final product.
1 organoleptic examination of test example
1.1 appearances: the visual observations under room temperature and non-direct sunlight of materialsing.
The sample of equivalent and regulation sample (providing by enterprises): being first individually placed in identical container by 1.2 fragrance,
It uses the blotting paper of wide 0.5cm~1.0cm, long 10cm~15cm as fragrant paper is commented, dips sample and regulation sample about 1cm- respectively
2cm (the two should approach), is identified with smell.
1. organoleptic examination result of table:
2 physical and chemical index of test example is examined
2.1 pH: (directly surveying method) is measured by method specified in GB/T135531.1.
2.2 heat-resisting
2.2.1 instrument: constant incubator: accuracy of temperature control ± 1 DEG C.
2.2.2 operation sequence: adjusting constant incubator arrive (40 ± 1) DEG C in advance, packaging one bottle of complete sample
It is placed in constant incubator.It takes out, restores to visual observations after room temperature afterwards for 24 hours.
2.3 cold-resistant
2.3.1 instrument: constant incubator: accuracy of temperature control ± 1 DEG C.
2.3.2 operation sequence: constant incubator is adjusted arrive (5 scholar 1) DEG C in advance, one bottle of sample of Packing Intact is placed in
In constant incubator.It takes out, restores to visual observations after room temperature afterwards for 24 hours.
2. physical and chemical inspection result of table:
3 product skin irritation of test example/erosion test
According to " cosmetics health specification " (version in 2015) skin irritation/corrosion test to Examples 1 to 3 containing white
Hair rattan and Flos Hibisci extract repair moisture retention water carry out dermoreaction scoring, test the present invention to mammal skin part whether
With stimulation or corrosiveness and its degree.Concrete operations are as follows:
3.1 tested materials: Examples 1 to 3 repairs moisture retention water containing solanum lyratum and Flos Hibisci extract, is not required to dilute, can be straight
It connects and uses stoste.
3.2 experimental animals and feeding environment
Preferred 4 adults, health, the white rabbit of skin zero damage, female and male, but jenny should be not
It is pregnant and do not farrow sternly.Experimental animal answers single cage to raise, and animal will at least adapt to 3d in experimental animal room environment before testing
Time.
Experimental animal and experimental animal room meet national respective specified.Selection standard mixed feed, drinking-water do not limit.
3.3 acute skin irritation test procedures
3.3.1 before test about for 24 hours, experimental animal back backbone diamond wool is cut, epidermis, unhairing range can not be damaged
Left and right each about 3cmx3cm.
3.3.2 Example 1~3 is repaired moisture retention water about 0.5mL (g) containing solanum lyratum and Flos Hibisci extract and is coated directly on
On skin, then with two layers of gauze (2.5cmx2.5cm) and one layer of glassine paper or the like cover, then with nonirritant adhesive plaster with
Bandage is fixed.Other side skin is as control.Using blocking test.It smears 1 time daily, continuously smears 14d.From second day
Start, cropping before smearing every time, removes residual tested material with water.After 1 hour observation smear position dermoreaction, by table 3,4 into
Row dermoreaction scoring, check plot and trial zone are equally handled.
3.3.3 daily every animal average integral evaluation of result: is calculated according to the following formula.Determine that skin irritatin is strong with table 5
Degree.
Daily every animal average integral=(∑ erythema oedema integral/animal subject number)/14
Skin wound repair evaluation criterion:
3 erythema of table and eschar evaluation criterion
| Dermoreaction | Integral |
| Without erythema | 0 |
| Slight erythema | 1 |
| Obvious erythema | 2 |
| Moderate~severe erythema | 3 |
| Severe erythema (aubergine) to slight eschar is formed | 4 |
| Top | 4 |
4 hydroderma evaluation criterion of table
5 skin irritation evaluation criterion of table
| Integral | Stimulus intensity standard |
| 0~0.5 | It is nonirritant |
| 0.5~2.0 | Slight stimulation |
| 2.0~6.0 | Moderate irritation meter |
| 6.0~8.0 | Strong and stimulating |
6 skin irritatin intensity ratings result of table
Conclusion: being known by table 6, trial zone and check plot, is formed almost without erythema and oedema occurs, illustrate that this contains solanum lyratum
Moisture retention water is repaired to the no skin irritation of white rabbit with Flos Hibisci extract.
The test of 4 Human body contrast of test example
Skin irritation test is carried out to the present invention, 6 adult females for choosing skin health do skin irritation test, in the past
Regiones brachii medialis domain is recipient site, and side is test block, and the other side is check plot, takes three pieces of cotton pads, is coated respectively containing implementation
Solanum lyratum and shrub althea flower moisture retention water 0.05g, Opera adlay water 0.05g, common vetch Nuo Nashumin skin-moisturizing, skin water prepared by example 1
0.05g is attached to inner forearm test block, is fixed with medical proof fabric, and the not edible maror of person, irritation food are applicable in during test
Object, Test sites do not get wet.Observation sight is opened for 24 hours to look into and the results are shown in Table 7.
Reparation moisture retention water Skin-test testing result of the table 7. containing solanum lyratum, Flos Hibisci extract:
Test result: the adlay that experimental group has been listed containing reparation moisture retention water and the control group of solanum lyratum, Flos Hibisci extract
Water, the result no significant difference of common vetch Nuo Nashumin skin-moisturizing, skin water and check plot also indifference.
The evaluation of 5 product efficacy of test example
5.1 moistening effects test: gravimetric detemination percentage of water loss experiment
5.1.1 preparing gravimetric detemination moisturizer percentage of water loss before test must carry out in a constant temperature, constant humidity environment.
5.1.2 proxima luce (prox. luc) is tested, the unsaturated carbonate potassium solution of certain volume is placed in drier bottom, keeps liquid depth big
In 1cm, porous barrier is placed thereon, is closed the lid, and is kept sealing state, is placed in 25 DEG C of environment, to water vapor in air
Divide it is constant after, about 43% relative humidity can be maintained.
5.1.3 using Examples 1 to 3 containing solanum lyratum, Flos Hibisci extract reparation moisture retention water as sample to be tested.
5.1.4 a certain amount of sample is weighed, the glass plate (relative humidity of 5cm × 5cm for posting 3M adhesive tape is coated uniformly on.
Amount of samples is about 2mg/cm2, is placed in the drier for filling potassium carbonate saturated aqueous solution (RH43%), after the placement section time
(2h, 4h, 6h, 8h) weighs the quality of sample, tests, is averaged three times in parallel.
5.1.5 percentage of water loss is calculated.
5.1.6 percentage of water loss
M1The quality of sample before placing；
M2The quality of sample after placement.
5.1.7 percentage of water loss the results are shown in Table 7.
7. percentage of water loss test result of table
| Time | 2h | 4h | 6h | 8h |
| Embodiment 1 | 5% | 12% | 17% | 35% |
| Embodiment 2 | 7% | 11% | 16% | 38% |
| Embodiment 3 | 5% | 11% | 13% | 36% |
The test of 5.2 antibacterial effects:
5.2.1 Bacteria Culture: taken before test staphylococcus aureus, escherichia coli, detection of Salmonella, pseudomonas aeruginosa,
The fresh strain inclined plane such as Candida albicans, it is seeded in nutrient broth medium and improvement Martin's culture medium, is trained in preference temperature
After supporting suitable time, with normal saline dilution to suitable concentration, viable count is measured, it is spare.
It takes sterilizing small test tube several when 5.2.2 testing, contains solanum lyratum, the rose of Sharon with corresponding culture medium dilution embodiment 1
The reparation moisture retention water of flower extract is respectively 100,50,25,12.5,6.25,3.12,1.56,0.78mg/ml be respectively charged into every pipe
Each 1ml takes suitable dilution grade bacterium solution 0.1ml in each antibacterial test tube, inoculum concentration be 105 test organisms, shake up, make test organisms with
Medical fluid comes into full contact with, and is placed in culture 16-24 observation test organisms growing state in 37 DEG C of incubators.With the non-growing minimum medicine of bacterium
Object concentration is the minimum inhibitory concentration of the drug.
5.2.3 antibacterial the results are shown in Table 8.
Fungistatic effect measurement result of the table 8. containing solanum lyratum, the reparation moisture retention water of Flos Hibisci extract:
Remarks: -- indicate no long bacterium ,+indicate a small amount of long bacterium, ++ indicate the long bacterium of appropriateness, +++ indicate a large amount of long bacterium.
Antibacterial inhibition zone result of the table 9. containing solanum lyratum, the reparation moisture retention water of Flos Hibisci extract:
| Strain name | Escherichia coli | Staphylococcus aureus | Bacillus subtilis |
| Bacteriostatic diameter | 8.02mm | 12.01mm | 11.02mm |
Known by table 8, containing solanum lyratum, Flos Hibisci extract reparation moisture retention water to staphylococcus aureus, large intestine angstrom sterilization,
The minimum inhibitory concentration (MIC) of detection of Salmonella, Candida albicans is 100mg/ml, to the minimum inhibitory concentration of pseudomonas aeruginosa
It (MIC) is 50mg/ml.
Test criterion according to antibacterial circle: it is extremely sensitive that antibacterial loop diameter, which is greater than 20mm,；15~20mm is high sensitive；10
~15mm is middle sensitivity；7~9mm is muting sensitive sense；It is insensitive less than 7mm.As shown in Table 9, it is extracted containing solanum lyratum, shrub althea flower
The bacterium that the reparation moisture retention water of object is common to three of the above has certain antibiotic property.
The evaluation of 6 human body experience sense of test example
It invites 90 between 20~50 years old, the female volunteers of skin health, is randomly divided into 9 groups, every group of 20 people, average year
Age 22 ± 2 years old, moisture retention water made from Examples 1 to 3 was tried out respectively, observes and experience using effect.Application method: volunteer is clear
After clean face, above-mentioned moisture retention water about 3mL is poured in cotton pads, soak cotton pads but will not be dripped, and determines cotton piece side
To so that cotton piece fiber orientation and finger vertical, are all covered on skin surface for cotton piece, gently press with finger, gently wipe
It wipes, so that repairing moisture retention water penetrates into skin, after wiping, accelerates to permeate with the mode patted, it is each daily morning and evening to use once,
Adhere to using one month, at least checks that once whether there is or not whole bodies and local adverse reaction with understanding weekly, and record result in detail.It surveys
Try assessment result such as the following table 10:
On probation (one month) feedback conclusive table of the table 10. containing solanum lyratum, the reparation moisture retention water of Flos Hibisci extract
From upper table 10:
Real the liking and approving by volunteer on probation of the present invention, it is mildly close that volunteer on probation indicates that this repairs moisture retention water
Skin is not stimulated, is easily absorbed, and using the salubrious non-greasy of rear face, feels dry skin, coarse, red capillary etc. after trying out one month
Problem be improved significantly, pore is reduced, and skin becomes smooth water profit, flexible.
All there is allergic phenomena in non-someone in volunteer on probation simultaneously, does not also occur pruitus, shouting pain, redness etc.
Situation.
Therefore, a kind of reparation moisture retention water containing solanum lyratum and Flos Hibisci extract of the present invention is mildly safe, can be used for a long time.
The above-described embodiments merely illustrate the principles and effects of the present invention, and is not intended to limit the present invention.It is any ripe
The personage for knowing this technology all without departing from the spirit and scope of the present invention, carries out modifications and changes to above-described embodiment.Cause
This, institute is complete without departing from the spirit and technical ideas disclosed in the present invention by those of ordinary skill in the art such as
At all equivalent modifications or change, should be covered by the claims of the present invention.
Claims (5)
1. a kind of reparation moisture retention water containing solanum lyratum and Flos Hibisci extract, which is characterized in that by following components in parts by weight system
At:
10 ~ 20 parts of solanum lyratum extracting solution；
10 ~ 20 parts of shrub althea flower extracting solution；
1 ~ 3 part of propylene glycol；
1 ~ 3 part of glycerol；
1 ~ 3 part of beta glucan；
1 ~ 3 part of allantoin；
0.2 ~ 0.5 part of water-soluble jojoba oil；
0.0008-0.002 parts of disodium ethylene diamine tetraacetate；
0.3 ~ 1 part of citric acid；
0.1 ~ 0.4 part of Phenoxyethanol；
Remaining is deionized water, and total amount is 100 parts.
2. a kind of reparation moisture retention water containing solanum lyratum and Flos Hibisci extract according to claim 1, which is characterized in that described
White hair boisiana extract the preparation method is as follows:
(1) solanum lyratum is cleaned and dries, clayed into power, cross 60 meshes and obtain climbing nightshade, weigh 20~50 parts by weight；
(2) it disperses climbing nightshade in deionized water, stirring is sufficiently mixed to obtain solanum lyratum suspension；Climbing nightshade with go
The mass ratio of ionized water is 1:10 ~ 20；
(3) heating solanum lyratum suspension is subsequently added into 1.0-1.5 part by weight of cellulose enzyme to 40~55 DEG C, stirs, and sufficiently reacts
2-3h；
(4) pectase of 0.6-1.2 parts by weight, stirring, sufficiently reaction 1-2h are added in the mixed solution of step (3)；
(5) step (4) mixed solution reduces temperature to 35~50 DEG C, adjusts pH to 4~5 with pH adjusting agent, filtering removes filter
Slag；
(6) 120-150 parts by weight are concentrated the filtrate to get white hair boisiana extract.
3. a kind of reparation moisture retention water containing solanum lyratum and Flos Hibisci extract according to claim 1, which is characterized in that described
Flos Hibisci extract the preparation method is as follows:
A1, by fresh shrub althea flower clean drain, its petal is separated, then its low temperature is lyophilized；
A2, the shrub althea flower after the drying of 20~40 parts by weight is weighed, is blended into powder, crosses 40 meshes, obtain shrub althea flower powder；
A3, the deionized water that 3 times of weight of shrub althea flower powder are added are impregnated, and pH adjusting agent tune pH to 4 is added, and add 0.5 ~ 1 parts by weight fine
Plain enzyme is tieed up, is sufficiently stirred, sets 1.5h in 40 ~ 50 DEG C of waters bath with thermostatic control, adding the mass concentration of 5 times of weight of shrub althea flower powder is 75%
Ethanol solution 1 ~ 2h of refluxing extraction, is filtered while hot, obtains first time extracting solution and the dregs of a decoction；
A4, ethanol solution 0.5 ~ 1h of refluxing extraction that the mass concentration of 5 times of weight of dosing slag is 50% into the dregs of a decoction, are filtered while hot,
Obtain second of extracting solution；
A5, first time extracting solution and second of extracting solution are mixed, ethyl alcohol is recycled in Rotary Evaporators evaporation, and centrifugation takes upper layer clear
Liquid is used, and extracting n-butyl alcohol 3 times, volatilize n-butanol, obtains Flos Hibisci extract.
4. a kind of reparation moisture retention water containing solanum lyratum and Flos Hibisci extract according to Claims 2 or 3, it is characterised in that:
The pH adjusting agent is the hydrochloric acid solution of 2.5mol/L.
5. a kind of preparation method of the reparation moisture retention water containing solanum lyratum and Flos Hibisci extract, which is characterized in that including following step
It is rapid:
S1, propylene glycol, glycerol, beta glucan, allantoin, water-soluble jojoba oil, citric acid and second are added in deionized water
Edetate disodium, and be heated to 70~80 DEG C, under keeping warm mode, 20 ~ 30min of stirring obtain material A to uniform；
S2, material A is cooled to 30~40 DEG C, Phenoxyethanol, white hair boisiana extract and Flos Hibisci extract is added, continues to stir
To uniform, material B is obtained；
S3, material B are cooled to -5 ~ -10 DEG C, and after keeping the temperature 30 ~ 60min, filtering, final pasteurising repairs moisture retention water to obtain the final product.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112754970A (en) * | 2021-03-10 | 2021-05-07 | 福建师范大学 | Facial mask liquid containing hibiscus flower extract and preparation method thereof |
| CN113018232A (en) * | 2021-03-10 | 2021-06-25 | 福建师范大学 | Eye cream containing hibiscus flower extract and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102000011A (en) * | 2010-11-26 | 2011-04-06 | 大连大学 | Shrub althea flower lotion and preparation method thereof |
| CN103446487A (en) * | 2013-10-07 | 2013-12-18 | 刘惠敏 | Preparation method of traditional Chinese medicine lotion for curing dried-ginger-overeating type bartholinitis |
| CN103446448A (en) * | 2013-10-07 | 2013-12-18 | 梅霞 | Preparation method of traditional Chinese medicine lotion for curing itching type bartholinitis |
| CN106456680A (en) * | 2013-08-20 | 2017-02-22 | 施韦特-莫迪国际公司 | Product comprising a plant for medicinal, cosmetic, coloring or dermatologic use |
| CN107308038A (en) * | 2017-06-09 | 2017-11-03 | 佛山汇沐化学科技有限公司 | It is a kind of that there is the facial mask for improving skin quality effect |
-
2019
- 2019-06-27 CN CN201910570117.6A patent/CN110200870A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102000011A (en) * | 2010-11-26 | 2011-04-06 | 大连大学 | Shrub althea flower lotion and preparation method thereof |
| CN106456680A (en) * | 2013-08-20 | 2017-02-22 | 施韦特-莫迪国际公司 | Product comprising a plant for medicinal, cosmetic, coloring or dermatologic use |
| CN103446487A (en) * | 2013-10-07 | 2013-12-18 | 刘惠敏 | Preparation method of traditional Chinese medicine lotion for curing dried-ginger-overeating type bartholinitis |
| CN103446448A (en) * | 2013-10-07 | 2013-12-18 | 梅霞 | Preparation method of traditional Chinese medicine lotion for curing itching type bartholinitis |
| CN107308038A (en) * | 2017-06-09 | 2017-11-03 | 佛山汇沐化学科技有限公司 | It is a kind of that there is the facial mask for improving skin quality effect |
Non-Patent Citations (1)
| Title |
|---|
| 宋丽雅: "《化妆品植物添加剂的研究与开发》", 30 September 2011 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112754970A (en) * | 2021-03-10 | 2021-05-07 | 福建师范大学 | Facial mask liquid containing hibiscus flower extract and preparation method thereof |
| CN113018232A (en) * | 2021-03-10 | 2021-06-25 | 福建师范大学 | Eye cream containing hibiscus flower extract and preparation method thereof |
| CN112754970B (en) * | 2021-03-10 | 2022-05-13 | 福建师范大学 | Facial mask liquid containing hibiscus flower extract and preparation method thereof |
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