CN110101588A - A kind of whitening and spot-eliminating composition and its shin moisturizer and preparation method - Google Patents
A kind of whitening and spot-eliminating composition and its shin moisturizer and preparation method Download PDFInfo
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- CN110101588A CN110101588A CN201910294008.6A CN201910294008A CN110101588A CN 110101588 A CN110101588 A CN 110101588A CN 201910294008 A CN201910294008 A CN 201910294008A CN 110101588 A CN110101588 A CN 110101588A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/447—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof containing sulfur
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
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- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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Abstract
The invention discloses a kind of whitening and spot-eliminating compositions, including following components by weight: 2-10 parts of ascorbic acid, 0.4-2 parts of kojic acids, 0.1-2 parts of tranexamic acids, 0.1-2 parts of alpha-arbutins, 0.1-1 parts of hydroxyethyl piperazine ethane sulfonic acids and 3-15 parts of tartaric acid and/or precursor.The whitening and spot-eliminating composition passes through generation, the damage absorbed while reducing ultraviolet light to skin metabolic by the acidification cutin-softening of tartaric acid and/or precursor promotion skin cell, improving effective component as biological buffer by hydroxyethyl piperazine ethane sulfonic acid inhibited tyrosinase activity to reduce melanin, the whitening and spot-eliminating composition effectively reduces the formation of melanin by many-sided effect, keeps skin more penetrating.The present invention also provides the shin moisturizer and preparation method thereof containing the whitening and spot-eliminating composition.
Description
Technical field
The present invention relates to daily fine chemicals, and in particular to whitening and spot-eliminating composition and its shin moisturizer and preparation method.
Background technique
The obscure freckle of skin is always to perplex the problem of vast Asia women.It is interior other than Mr.'s reason of genetic aspect
Diacrisis, scytitis, solarization visible light, extraneous contamination and free radical invasion, age increase and aging, chemical substance dirt
The external bad condition such as dye and stimulation is also to cause yellowish-brown, obscure, sunburn several big great reasons of skin.Simultaneous chemistry
Environmental pollution is serious, the addition of diet articles chemistry increases, and the undesirable element of these synthesis leads to the coarse dark and gloomy phenomenon of facial skin
More and more extensiveization and sternnessization.
Skin is dark and gloomy and pigmented spots are from the point of view of angle of physiology, and it is melanin pigmentation due to accumulating over a long period that skin is dark and gloomy,
Color spot is that pigmentation is unevenly distributed, leads to the spot of localized clusters colour of skin depth.Solarization is excessive, endocrine disorder, diet are not advised
Model, the sleep daily schedule is insufficient and lack of standardization, cosmetics improper use initiation pachylosis is dark and gloomy and color spot.In general, beautiful
White nti-freckle answer it is multi-faceted escorted conditioning, achieve the effect that temporary solution again effect a permanent cure.
Summary of the invention
For overcome the deficiencies in the prior art, one of the objects of the present invention is to provide one kind effectively to desalinate blackspot, disappears
Except skin is obscure, the whitening and spot-eliminating composition of promotion skin new life.Pass through raising cell to the whitening and spot-eliminating composition concertedness
Permeability reduces activity and black that ultraviolet light inhibits tyrosinase to the injury of skin, removal aging cutin, multiple action
The formation of element, to make the light spot of skin, whitening, penetrating.
The second object of the present invention is to provide the shin moisturizer comprising the whitening and spot-eliminating composition.In the shin moisturizer effectively at
The water oil dispersed divided is uniform and stable, and effective component permeability is strong.
The third object of the present invention is to provide the preparation method of the shin moisturizer.This method is each effective in technical process
The lossy of ingredient is low, it is effective component be evenly distributed, grease system phase is stablized.
An object of the present invention adopts the following technical scheme that realization:
A kind of whitening and spot-eliminating composition, including following components by weight: 2-10 parts of ascorbic acid, 0.4-2 parts of songs
Acid, 0.1-2 parts of tranexamic acids, 0.1-2 parts of alpha-arbutins, 0.1-1 parts of hydroxyethyl piperazine ethane sulfonic acids and 3-15 parts of tartaric acid and/or preceding
Body.
The whitening and spot-eliminating composition passes through with the Reverse transcriptase of hydroquinone type derivative alpha-arbutin and reproducibility suppression
It is made as the first layer defence to tyrosinase, and inhibits to be used as second by the reproducibility of antioxidants Ascorbic acid and kojic acid
Layer defence, the last Reverse transcriptase using mildly stable tranexamic acid is as third layer defence, thus effectively stability
The formation for inhibiting tyrosinase inhibits the generation of melanin from source.
Tartaric acid and/or preceding physical efficiency in the whitening and spot-eliminating composition effectively soften and remove aging cutin, improve it is coarse and
It is obscure, dry skin and sense of discomfort are reduced, mutually promotes with to tyrosinase constituents for suppressing, to reduce pigmentation, makes skin light
It is sliding bright.Specifically, tartaric acid and/or precursor include hydroxyacetic acid, lactic acid and gluconolactone.Preferably hydroxyacetic acid, lactic acid
1:(1-2 is pressed with gluconolactone): the weight ratio of (1-3) composition, to form in irritation, oxidation resistant combination；
The whitening and spot-eliminating composition can also further include 0.05-2 parts of cysteines.Cysteine is as complexing
Inhibitor, mutually act synergistically with ascorbic acid, kojic acid, tranexamic acid and alpha-arbutin, heavy metal ion, freedom can be effectively reduced
Influence of the base to skin.
The whitening and spot-eliminating composition can also further include 0.1-1 parts of taurines and 0.05-1 parts of panthenols.The two category
In nutrition class moisturizer, skin metabolism can be effectively adjusted, increases cell activity and penetration, improve skin immunity and self is repaired
Reactivation power.
Specifically, which includes following components by weight: 4-6 parts of ascorbic acid, 0.5-1.5
Part kojic acid, 0.5-1.5 parts of tranexamic acids, 0.5-1.5 parts of alpha-arbutins, 0.5-0.8 parts of cysteines, 0.4-0.6 parts of ethoxy piperazines
Piperazine ethane sulfonic acid, 1.5-2.5 part hydroxyacetic acid, 2.5-3.5 parts of lactic acid, 4-6 parts of gluconolactones, 0.4-0.6 parts of taurines and
0.8-1 parts of panthenols.
The second object of the present invention adopts the following technical scheme that realization:
A kind of shin moisturizer, by above-mentioned whitening and spot-eliminating composition and 1-5 parts of urea, 0.05-1.5 parts of PEG-40 hydrogenated castors
It oil, 1-15 parts of auxiliary materials, the alkali for adjusting pH to 4.0-6.0 and supplies 100 parts of water and is made；The auxiliary material includes thickener, pigment
And essence.
The shin moisturizer has stable water oil phase, can effectively moisturizing water lock, absorption of the promotion skin to TYR enzyme press down
The formation of melanin processed promotes the metabolism of skin cell, removes aging cutin, reduces the inflammation of eczema, to keep skin logical
It is thoroughly ruddy.
Further, it includes hydroxyethyl cellulose and PEG/PPG-17/6 copolymerization that the cream as water oil phase, which determines the thickener of agent,
Object.
Further, the shin moisturizer is by whitening and spot-eliminating composition and 2.5-3.5 parts of urea, 0.2-0.8 parts of PEG-40 hydrogenations
Castor oil and auxiliary material are made；
The whitening and spot-eliminating composition includes following components by weight: 4-6 parts of ascorbic acid, 0.5-1.5 parts of songs
Acid, 0.5-1.5 parts of tranexamic acids, 0.5-1.5 parts of alpha-arbutins, 0.5-0.8 parts of cysteines, 0.4-0.6 parts of hydroxyethyl piperazine second
Alkyl sulfonic acid, 1.5-2.5 part hydroxyacetic acid, 2.5-3.5 parts of lactic acid, 4-6 parts of gluconolactones, 0.4-0.6 parts of taurines and 0.8-1
Part panthenol；
Auxiliary material is by 0.1-0.3 parts of hydroxyethyl celluloses, 0.8-1.2 parts of PEG/PPG-17/6 copolymers, 0.4-0.6 parts of pigments
With the alkali composition for adjusting pH to 4.0-6.0.
Wherein, the alkali for adjusting pH is sodium hydroxide or potassium hydroxide.
The third object of the present invention adopts the following technical scheme that realization:
A method of preparing above-mentioned shin moisturizer, comprising the following steps:
1) add water to dissolve by heating part thickener, stir；
2) tartaric acid and/or precursor and ascorbic acid, heating stirring dissolution are added into the material 1) obtained；
3) alkali soluble is obtained into pH in water and adjusts liquid, pH is added into the material that step 2) obtains adjusted liquid and be adjusted to pH and be
4.0-6.0；
4) whitening and spot-eliminating composition, urea and pigment are mixed, is added in the material of step 3)；
5) thickener of surplus, Cremophor RH40 and essence are uniformly mixed, are added in the material of step 4),
Matter；
6) material of step 5) is adjusted into liquid by pH and is adjusted to pH=4.0-6.0, obtain shin moisturizer.
Further, the thickener in step 1) is hydroxyethyl cellulose, and thickener is PEG/PPG-17/6 in step 2)
Copolymer
Compared with prior art, the beneficial effects of the present invention are:
Whitening and spot-eliminating composition of the invention by biological buffer hydroxyethyl piperazine ethane sulfonic acid, cutin softening removal at
The multiple action for dividing tartaric acid and/or precursor and tyrosine inhibition ingredient kojic acid, tranexamic acid and alpha-arbutin, can effectively reduce flesh
Free-radical oxidation, the black and white element of skin are calm, provide the whitening and spot-eliminating composition of the low stimulation of one kind, high moisturizing, high skin toner sense；
The present invention provides a kind of shin moisturizer including above-mentioned whitening and spot-eliminating composition, passes through the moisturizing of urea, PEG-40 hydrogen
Homogeneous and thickener the stabilization etc. for changing castor oil makes the shin moisturizer have more stable water oil phase state and preferable
Feel skin sense, the water lock using rear skin are good.
The present invention, which passes through, also provides a kind of preparation method of shin moisturizer, by way of grouping mixing and step-wise dissolution,
The loss of effective component is effectively reduced, makes preferably to be distributed in system between effective component, meanwhile, form stable water
Oily phase, long shelf-life.
Specific embodiment
In the following, being described further in conjunction with specific embodiment to the present invention, it should be noted that is do not collided
Under the premise of, new embodiment can be formed between various embodiments described below or between each technical characteristic in any combination.This reality
Apply employed in example to material be commercially available.
The present invention provides a kind of whitening and spot-eliminating composition, including following components by weight: 2-10 parts of ascorbic acid,
0.4-2 parts of kojic acids, 0.1-2 parts of tranexamic acids, 0.1-2 parts of alpha-arbutins, 0.1-1 parts of hydroxyethyl piperazine ethane sulfonic acids and 3-15 portions of fruits
Acid and/or precursor.
The present invention provides a kind of shin moisturizer, by above-mentioned whitening and spot-eliminating composition and 1-5 parts of urea, 0.05-1.5 parts of PEG-40
It rilanit special, 1-15 part auxiliary material, the alkali for adjusting pH to 4.0-6.0 and supplies 100 parts of water and is made；The auxiliary material includes thickening
Agent, pigment and essence.
The present invention also provides a kind of methods for preparing above-mentioned shin moisturizer.
A method of preparing above-mentioned shin moisturizer, comprising the following steps:
1) add water to dissolve by heating part thickener, stir；
2) tartaric acid and/or precursor and ascorbic acid, heating stirring dissolution are added into the material 1) obtained；
3) alkali soluble is obtained into pH in water and adjusts liquid, pH is added into the material that step 2) obtains adjusted liquid and be adjusted to pH and be
4.0-6.0；
4) whitening and spot-eliminating composition, urea and pigment are mixed, is added in the material of step 3)；
5) thickener of surplus, Cremophor RH40 and essence are uniformly mixed, are added in the material of step 4),
Matter；
6) material of step 5) is adjusted into liquid by pH and is adjusted to pH=4.0-6.0, obtain shin moisturizer.
It is specific embodiment of the present invention below, used raw material, equipment etc. remove special limit in the following embodiments
It can be obtained by buying pattern outside fixed.In following specific embodiments, documented pigment is burnt sugar coloring, is made into before use
The aqueous solution of 10wt%.
Embodiment 1:
A kind of whitening and spot-eliminating composition, is made of following components by weight: 5 parts of ascorbic acid, 1 part of kojic acid, 1 part
Tranexamic acid, 1 part of alpha-arbutin, 0.6 part of cysteine, 0.5 part of hydroxyethyl piperazine ethane sulfonic acid, 2 parts of hydroxyacetic acids, 3 parts of lactic acid,
5 parts of gluconolactones, 0.5 part of taurine and 1 part of panthenol.
Embodiment 2:
A kind of whitening and spot-eliminating composition, is made of following components by weight: 6 parts of ascorbic acid, 1.5 parts of kojic acids,
1.5 parts of tranexamic acids, 0.5 part of alpha-arbutin, 0.5 part of cysteine, 0.6 part of hydroxyethyl piperazine ethane sulfonic acid, 1.5 parts of hydroxyl second
Acid, 3.5 parts of lactic acid, 6 parts of gluconolactones, 0.6 part of taurine and 0.8 part of panthenol.
Embodiment 3:
A kind of whitening and spot-eliminating composition, is made of following components by weight: 4 parts of ascorbic acid, 0.5 part of kojic acid,
0.5 part of tranexamic acid, 1.5 parts of alpha-arbutins, 0.8 part of cysteine, 0.4 part of hydroxyethyl piperazine ethane sulfonic acid, 2.5 parts of hydroxyl second
Acid, 2.5 parts of lactic acid, 4 parts of gluconolactones, 0.4 part of taurine and 0.9 part of panthenol.
Embodiment 4:
A kind of shin moisturizer, the whitening and spot-eliminating composition obtained by embodiment 1,0.2 part of hydroxyethyl cellulose, 3 parts of urea,
0.3 part of Cremophor RH40,1 part of PEG/PPG-17/6 copolymer, 0.5 part of pigment and the hydrogen-oxygen for adjusting pH to 4.0-6.0
Change sodium composition.
Embodiment 5:
A kind of shin moisturizer, the whitening and spot-eliminating composition obtained by embodiment 2,0.1 part of hydroxyethyl cellulose, 3.5 parts of urea,
0.8 part of Cremophor RH40,1.2 parts of PEG/PPG-17/6 copolymers, 0.6 part of pigment, the hydrogen-oxygen for adjusting pH to 4.0-6.0
Change sodium and 0.1 part of essence composition.
Embodiment 6:
A kind of shin moisturizer, the whitening and spot-eliminating composition obtained by embodiment 3,0.3 part of hydroxyethyl cellulose, 2.5 parts of urea,
0.2 part of Cremophor RH40,0.8 part of PEG/PPG-17/6 copolymer, 0.4 part of pigment, the hydrogen-oxygen for adjusting pH to 4.0-6.0
Change sodium and 0.5 part of essence composition.
Prepare shin moisturizer shown in embodiment 4-6, comprising the following steps:
1) hydroxyethyl cellulose adds water to be heated to 75-80 DEG C of dissolution, insulated and stirred；
2) it is molten that hydroxyacetic acid, lactic acid, gluconolactone and ascorbic acid, heating stirring are added into the material 1) obtained
Solution；
3) hydroxide is dissolved in water and obtains the pH adjusting liquid that concentration is 10wt%, pH is added into the material that step 2) obtains
Adjusting liquid and being adjusted to pH is 4.0-6.0；
4) auxiliary material of the whitening and spot-eliminating composition of surplus, surplus is mixed, is added in the material of step 3)；
5) PEG/PPG-17/6 copolymer, Cremophor RH40 and essence are uniformly mixed, add to the object of step 4)
In material, homogeneous；
6) material of step 5) is adjusted into liquid by pH and is adjusted to pH=4.0-6.0, obtain shin moisturizer.
Performance detection and effect assessment
1. white-skinned face function is tested
Female volunteers 60 of volunteer 20-40 years old are selected, are randomly divided into 3 groups, every group of 20 people try out embodiment respectively
4, it uses after 5,6 shin moisturizer face cleaning every night 1 time, as a comparison case using commercially available Eradicates spot frost, after 2 months, uses
Situation result feedback is as follows:
Table 1 uses the observed result after 2 months
30 days after the test, the skin of volunteer is observed, as a result as shown in the table.
Observed result after 2 off-test of table 30 days
Just as shown in Table 1 and Table 2, the shin moisturizer provided by the invention containing whitening and spot-eliminating composition has preferable whitening
Light spot ingredient, allergic reaction situation are less.And shin moisturizer provided by the invention deactivates rear allergic conditions and subsides completely, but skin
Skin has no obvious obscure.
2. storage stability is tested
By the obtained shin moisturizer of embodiment 4-6 be placed in 42 ± 2 DEG C baking oven store 14 days, respectively record the 1st day, the 3rd day,
The character of 6th day and the 14th day shin moisturizer, as a result as shown in the table:
The test of 3 thermal-stable of table
As seen from the above table, shin moisturizer provided by the invention does not generate apparent water oil phase, system tool under thermal environment
There is preferable stability.
The above embodiment is only the preferred embodiment of the present invention, and the scope of protection of the present invention is not limited thereto,
The variation and replacement for any unsubstantiality that those skilled in the art is done on the basis of the present invention belong to institute of the present invention
Claimed range.
Claims (10)
1. a kind of whitening and spot-eliminating composition, which is characterized in that including following components by weight: 2-10 parts of ascorbic acid,
0.4-2 parts of kojic acids, 0.1-2 parts of tranexamic acids, 0.1-2 parts of alpha-arbutins, 0.1-1 parts of hydroxyethyl piperazine ethane sulfonic acids and 3-15 portions of fruits
Acid and/or precursor.
2. whitening and spot-eliminating composition as described in claim 1, which is characterized in that the tartaric acid and/or precursor include hydroxyl second
Acid, lactic acid and gluconolactone.
3. whitening and spot-eliminating composition as described in claim 1, which is characterized in that further include 0.05-2 parts of cysteines.
4. whitening and spot-eliminating composition as described in claim 1, which is characterized in that further include 0.1-1 parts of taurines and 0.05-1
Part panthenol.
5. whitening and spot-eliminating composition as described in claim 1, which is characterized in that including following components by weight: 4-6
Part ascorbic acid, 0.5-1.5 parts of kojic acids, 0.5-1.5 parts of tranexamic acids, 0.5-1.5 parts of alpha-arbutins, 0.5-0.8 parts of cysteines,
0.4-0.6 parts of hydroxyethyl piperazine ethane sulfonic acids, 1.5-2.5 parts of hydroxyacetic acids, 2.5-3.5 parts of lactic acid, 4-6 parts of gluconolactones,
0.4-0.6 parts of taurines and 0.8-1 parts of panthenols.
6. a kind of shin moisturizer, which is characterized in that urinated by the described in any item whitening and spot-eliminating compositions of claim 1-5 and 1-5 parts
Element, 0.05-1.5 parts of Cremophor RH40s, 1-15 parts of auxiliary materials, the alkali for adjusting pH to 4.0-6.0 and the water system for supplying 100 parts
At；The auxiliary material includes thickener, pigment and essence.
7. shin moisturizer as claimed in claim 6, which is characterized in that the thickener includes hydroxyethyl cellulose and PEG/PPG-
17/6 copolymer.
8. shin moisturizer as claimed in claim 6, which is characterized in that by whitening and spot-eliminating composition and 2.5-3.5 parts of urea, 0.2-
0.8 part of Cremophor RH40 and auxiliary material are made；
The whitening and spot-eliminating composition includes following components by weight: 4-6 parts of ascorbic acid, 0.5-1.5 parts of kojic acids,
0.5-1.5 parts of tranexamic acids, 0.5-1.5 parts of alpha-arbutins, 0.5-0.8 parts of cysteines, 0.4-0.6 parts of hydroxyethyl piperazine ethane sulphurs
Acid, 1.5-2.5 parts of hydroxyacetic acids, 2.5-3.5 parts of lactic acid, 4-6 parts of gluconolactones, 0.4-0.6 parts of taurines and 0.8-1 parts are general
Alcohol；
Auxiliary material is by 0.1-0.3 parts of hydroxyethyl celluloses, 0.8-1.2 parts of PEG/PPG-17/6 copolymers, 0.4-0.6 parts of pigments and tune
Save the alkali composition of pH to 4.0-6.0.
9. a kind of prepare the method such as the described in any item shin moisturizer of claim 6-8, which comprises the following steps:
1) add water to dissolve by heating part thickener, stir；
2) tartaric acid and/or precursor and ascorbic acid, heating stirring dissolution are added into the material 1) obtained；
3) alkali soluble is obtained into pH in water and adjusts liquid, it is 4.0- that pH is added into the material that step 2) obtains and adjusts liquid to be adjusted to pH
6.0；
4) the whitening and spot-eliminating composition of surplus, urea and pigment are mixed, is added in the material of step 3)；
5) thickener of surplus, Cremophor RH40 and essence are uniformly mixed, are added in the material of step 4), homogeneous；
6) material of step 5) is adjusted into liquid by pH and is adjusted to pH=4.0-6.0, obtain shin moisturizer.
10. method as claimed in claim 9, which is characterized in that the thickener in step 1) is hydroxyethyl cellulose, step 2)
Middle thickener is PEG/PPG-17/6 copolymer.
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