CN110050061A - 从具有MeCP2破坏的诱导多能干细胞生成成熟谱系 - Google Patents

从具有MeCP2破坏的诱导多能干细胞生成成熟谱系 Download PDF

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CN110050061A
CN110050061A CN201780070553.6A CN201780070553A CN110050061A CN 110050061 A CN110050061 A CN 110050061A CN 201780070553 A CN201780070553 A CN 201780070553A CN 110050061 A CN110050061 A CN 110050061A
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cells
cell
mecp2
differentiation
hpc
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D·拉杰时
A·斯托鲁瑟
S·伯顿
C·姆恩
B·斯瓦森
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Fuji Film Cell Power Co
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Fuji Film Cell Power Co
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CN201780070553.6A 2016-10-05 2017-10-05 从具有MeCP2破坏的诱导多能干细胞生成成熟谱系 Pending CN110050061A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662404430P 2016-10-05 2016-10-05
US62/404,430 2016-10-05
PCT/US2017/055353 WO2018067826A1 (en) 2016-10-05 2017-10-05 Generating mature lineages from induced pluripotent stem cells with mecp2 disruption

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CN110050061A true CN110050061A (zh) 2019-07-23

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CN201780070553.6A Pending CN110050061A (zh) 2016-10-05 2017-10-05 从具有MeCP2破坏的诱导多能干细胞生成成熟谱系

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US (1) US10961505B2 (https=)
EP (1) EP3523422B1 (https=)
JP (2) JP7248571B2 (https=)
CN (1) CN110050061A (https=)
AU (2) AU2017340634B2 (https=)
CA (1) CA3038690A1 (https=)
DK (1) DK3523422T3 (https=)
ES (1) ES3009605T3 (https=)
WO (1) WO2018067826A1 (https=)

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CN114426951A (zh) * 2020-10-29 2022-05-03 北京赛尔湃腾科技咨询合伙企业(有限合伙) 利用多能干细胞制备小胶质细胞样细胞的方法
CN116426472A (zh) * 2023-06-08 2023-07-14 呈诺再生医学科技(北京)有限公司 一种促进造血干细胞或造血祖细胞分化为红细胞的诱导分化体系及其应用

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US12281334B2 (en) 2017-04-14 2025-04-22 Children's Hospital Medical Center Multi donor stem cell compositions and methods of making same
EP3694603B1 (en) 2017-10-10 2026-04-08 Children's Hospital Medical Center Esophageal tissue and/or organoid compositions and methods of making same
US12379372B2 (en) 2017-12-21 2025-08-05 Children's Hospital Medical Center Digitalized human organoids and methods of using same
KR20210045360A (ko) 2018-05-16 2021-04-26 신테고 코포레이션 가이드 rna 설계 및 사용을 위한 방법 및 시스템
KR102887406B1 (ko) 2018-07-26 2025-11-19 칠드런즈 호스피탈 메디칼 센터 간-담도-췌장 조직 및 이를 제조하는 방법
AU2019339410A1 (en) * 2018-09-12 2021-04-15 Children's Hospital Medical Center Organoid compositions for the production of hematopoietic stem cells and derivatives thereof
WO2020093025A1 (en) * 2018-11-01 2020-05-07 Synthego Corporation Methods for knock-out of a target sequence through introduction of a premature stop codon
JP7446242B2 (ja) * 2018-12-20 2024-03-08 住友化学株式会社 胚型赤芽球を含む細胞集団及びその製造方法、細胞培養組成物並びに化合物試験法
WO2020160371A1 (en) 2019-02-01 2020-08-06 The University Of Hong Kong Innervated organoid compositions and methods of making same
JP7701879B2 (ja) * 2019-05-28 2025-07-02 エフ. ホフマン-ラ ロシュ アーゲー 単球前駆細胞を生成するための方法
WO2020243633A1 (en) 2019-05-31 2020-12-03 Children's Hospital Medical Center Shaped organoid compositions and methods of making same
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JP2022537278A (ja) * 2019-06-14 2022-08-25 フジフィルム セルラー ダイナミクス,インコーポレイテッド 帯電表面を使用して誘導多能性幹細胞から複数の系統を産生するための方法
JP7771053B2 (ja) * 2020-05-13 2025-11-17 Agc株式会社 ヒトプロフェッショナル抗原提示細胞の製造方法
AU2021275995B2 (en) 2020-05-22 2026-02-12 Insitro, Inc. Predicting disease outcomes using machine learned models
AU2022229913A1 (en) * 2021-03-05 2023-09-21 The Children's Medical Center Corporation Stroma-free nk cell differentiation from human pluripotent stem cells
DE202022002866U1 (de) 2021-04-01 2024-03-20 The Regents Of The University Of California Genetische Modifikation von Säugetierzellen zur Verleihung von Resistenz gegen CSF1R-Antagonisten
KR20240051185A (ko) * 2021-08-19 2024-04-19 세다르스-신나이 메디칼 센터 노화-관련 및 신경변성 질환의 예방 및 치료에서 ipsc-유래 면역 세포
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