CN110050061A - 从具有MeCP2破坏的诱导多能干细胞生成成熟谱系 - Google Patents
从具有MeCP2破坏的诱导多能干细胞生成成熟谱系 Download PDFInfo
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- CN110050061A CN110050061A CN201780070553.6A CN201780070553A CN110050061A CN 110050061 A CN110050061 A CN 110050061A CN 201780070553 A CN201780070553 A CN 201780070553A CN 110050061 A CN110050061 A CN 110050061A
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662404430P | 2016-10-05 | 2016-10-05 | |
| US62/404,430 | 2016-10-05 | ||
| PCT/US2017/055353 WO2018067826A1 (en) | 2016-10-05 | 2017-10-05 | Generating mature lineages from induced pluripotent stem cells with mecp2 disruption |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110050061A true CN110050061A (zh) | 2019-07-23 |
Family
ID=60153502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780070553.6A Pending CN110050061A (zh) | 2016-10-05 | 2017-10-05 | 从具有MeCP2破坏的诱导多能干细胞生成成熟谱系 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10961505B2 (https=) |
| EP (1) | EP3523422B1 (https=) |
| JP (2) | JP7248571B2 (https=) |
| CN (1) | CN110050061A (https=) |
| AU (2) | AU2017340634B2 (https=) |
| CA (1) | CA3038690A1 (https=) |
| DK (1) | DK3523422T3 (https=) |
| ES (1) | ES3009605T3 (https=) |
| WO (1) | WO2018067826A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114426951A (zh) * | 2020-10-29 | 2022-05-03 | 北京赛尔湃腾科技咨询合伙企业(有限合伙) | 利用多能干细胞制备小胶质细胞样细胞的方法 |
| CN116426472A (zh) * | 2023-06-08 | 2023-07-14 | 呈诺再生医学科技(北京)有限公司 | 一种促进造血干细胞或造血祖细胞分化为红细胞的诱导分化体系及其应用 |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9719068B2 (en) | 2010-05-06 | 2017-08-01 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| CN106661548B (zh) | 2014-05-28 | 2020-12-11 | 儿童医院医疗中心 | 用于经由定向分化将前体细胞转化为胃组织的方法和系统 |
| KR102729404B1 (ko) | 2016-11-04 | 2024-11-14 | 칠드런즈 호스피탈 메디칼 센터 | 간 유사 장기 조성물 및 이를 제조 및 사용하는 방법 |
| US12281334B2 (en) | 2017-04-14 | 2025-04-22 | Children's Hospital Medical Center | Multi donor stem cell compositions and methods of making same |
| EP3694603B1 (en) | 2017-10-10 | 2026-04-08 | Children's Hospital Medical Center | Esophageal tissue and/or organoid compositions and methods of making same |
| US12379372B2 (en) | 2017-12-21 | 2025-08-05 | Children's Hospital Medical Center | Digitalized human organoids and methods of using same |
| KR20210045360A (ko) | 2018-05-16 | 2021-04-26 | 신테고 코포레이션 | 가이드 rna 설계 및 사용을 위한 방법 및 시스템 |
| KR102887406B1 (ko) | 2018-07-26 | 2025-11-19 | 칠드런즈 호스피탈 메디칼 센터 | 간-담도-췌장 조직 및 이를 제조하는 방법 |
| AU2019339410A1 (en) * | 2018-09-12 | 2021-04-15 | Children's Hospital Medical Center | Organoid compositions for the production of hematopoietic stem cells and derivatives thereof |
| WO2020093025A1 (en) * | 2018-11-01 | 2020-05-07 | Synthego Corporation | Methods for knock-out of a target sequence through introduction of a premature stop codon |
| JP7446242B2 (ja) * | 2018-12-20 | 2024-03-08 | 住友化学株式会社 | 胚型赤芽球を含む細胞集団及びその製造方法、細胞培養組成物並びに化合物試験法 |
| WO2020160371A1 (en) | 2019-02-01 | 2020-08-06 | The University Of Hong Kong | Innervated organoid compositions and methods of making same |
| JP7701879B2 (ja) * | 2019-05-28 | 2025-07-02 | エフ. ホフマン-ラ ロシュ アーゲー | 単球前駆細胞を生成するための方法 |
| WO2020243633A1 (en) | 2019-05-31 | 2020-12-03 | Children's Hospital Medical Center | Shaped organoid compositions and methods of making same |
| WO2020243613A1 (en) | 2019-05-31 | 2020-12-03 | Children's Hospital Medical Center | Methods of generating and expanding hematopoietic stem cells |
| JP2022537278A (ja) * | 2019-06-14 | 2022-08-25 | フジフィルム セルラー ダイナミクス,インコーポレイテッド | 帯電表面を使用して誘導多能性幹細胞から複数の系統を産生するための方法 |
| JP7771053B2 (ja) * | 2020-05-13 | 2025-11-17 | Agc株式会社 | ヒトプロフェッショナル抗原提示細胞の製造方法 |
| AU2021275995B2 (en) | 2020-05-22 | 2026-02-12 | Insitro, Inc. | Predicting disease outcomes using machine learned models |
| AU2022229913A1 (en) * | 2021-03-05 | 2023-09-21 | The Children's Medical Center Corporation | Stroma-free nk cell differentiation from human pluripotent stem cells |
| DE202022002866U1 (de) | 2021-04-01 | 2024-03-20 | The Regents Of The University Of California | Genetische Modifikation von Säugetierzellen zur Verleihung von Resistenz gegen CSF1R-Antagonisten |
| KR20240051185A (ko) * | 2021-08-19 | 2024-04-19 | 세다르스-신나이 메디칼 센터 | 노화-관련 및 신경변성 질환의 예방 및 치료에서 ipsc-유래 면역 세포 |
| CN116640728B (zh) * | 2023-07-24 | 2023-10-20 | 呈诺再生医学科技(北京)有限公司 | RO8191和AS2863619在诱导产生表达成人型β珠蛋白的脱核红细胞中的应用 |
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| ES3009605T3 (en) | 2025-03-27 |
| US20180179496A1 (en) | 2018-06-28 |
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| AU2022224800A1 (en) | 2022-09-29 |
| EP3523422A1 (en) | 2019-08-14 |
| JP2019528773A (ja) | 2019-10-17 |
| AU2017340634A1 (en) | 2019-04-18 |
| WO2018067826A1 (en) | 2018-04-12 |
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