CN110049970B - 作为细菌氨酰-trna合成酶抑制剂的2-氨基-n-(芳基亚磺酰基)-乙酰胺化合物 - Google Patents

作为细菌氨酰-trna合成酶抑制剂的2-氨基-n-(芳基亚磺酰基)-乙酰胺化合物 Download PDF

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CN110049970B
CN110049970B CN201780074911.0A CN201780074911A CN110049970B CN 110049970 B CN110049970 B CN 110049970B CN 201780074911 A CN201780074911 A CN 201780074911A CN 110049970 B CN110049970 B CN 110049970B
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CN110049970A (zh
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保罗·威廉·芬
迈克尔·查尔顿
格雷斯·埃德蒙
艾加尔斯·吉尔格森斯
艾纳斯·洛萨
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Oxford Drug Design Ltd
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CN201780074911.0A 2016-10-07 2017-10-06 作为细菌氨酰-trna合成酶抑制剂的2-氨基-n-(芳基亚磺酰基)-乙酰胺化合物 Active CN110049970B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1617064.9 2016-10-07
GBGB1617064.9A GB201617064D0 (en) 2016-10-07 2016-10-07 Compounds and their therapeutic use
PCT/EP2017/075567 WO2018065611A1 (en) 2016-10-07 2017-10-06 2-amino-n-(arylsulfinyl)-acetamide compounds as inhibitors of bacterial aminoacyl-trna synthetase

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CN110049970A CN110049970A (zh) 2019-07-23
CN110049970B true CN110049970B (zh) 2023-04-11

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US (1) US11802110B2 (https=)
EP (1) EP3523282A1 (https=)
JP (1) JP6906608B2 (https=)
KR (1) KR102437676B1 (https=)
CN (1) CN110049970B (https=)
AU (1) AU2017339104B2 (https=)
CA (1) CA3038892C (https=)
EA (1) EA201990855A1 (https=)
GB (1) GB201617064D0 (https=)
IL (1) IL265790B2 (https=)
MA (1) MA46449A (https=)
MX (1) MX388072B (https=)
WO (1) WO2018065611A1 (https=)
ZA (1) ZA201902765B (https=)

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EA036995B1 (ru) * 2015-02-13 2021-01-25 Оксфорд Драг Дизайн Лимитед НОВЫЕ N-АЦИЛАРИЛСУЛЬФОНАМИДНЫЕ ПРОИЗВОДНЫЕ В КАЧЕСТВЕ ИНГИБИТОРОВ АМИНОАЦИЛ-тРНК СИНТЕТАЗЫ
GB201617064D0 (en) 2016-10-07 2016-11-23 Inhibox Limited And Latvian Institute Of Organic Synthesis The Compounds and their therapeutic use
CN110642758A (zh) * 2019-09-05 2020-01-03 浙江杰上杰新材料有限公司 一种对甲苯磺酰氨基脲发泡剂的合成方法
CN110642760A (zh) * 2019-09-05 2020-01-03 浙江杰上杰新材料有限公司 一种对甲苯亚磺酸锌的合成方法
CN110642759A (zh) * 2019-09-05 2020-01-03 浙江杰上杰新材料有限公司 一种苯亚磺酸锌的合成方法
MX2022007500A (es) * 2019-12-19 2022-07-04 Oxford Drug Design Ltd Compuestos de 2-amino-n-(amino-oxo-aril-lambda6-sulfanilideno)acet amida y su uso terapeutico.
WO2025108986A1 (en) 2023-11-21 2025-05-30 Oxford Drug Design Limited 2-amino-n-(oxo-aryl-lambda6-sulfanylidene)acetamide compounds and their therapeutic use
CN117510380B (zh) * 2024-01-08 2024-04-05 寿光诺盟化工有限公司 一种苯磺酸酯的制备方法

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CN110049970A (zh) 2019-07-23
MA46449A (fr) 2021-05-05
ZA201902765B (en) 2021-10-27
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AU2017339104A1 (en) 2019-05-23
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