CN110025529A - A kind of mild shampoo and preparation method thereof suitable for the pregnancy period - Google Patents

A kind of mild shampoo and preparation method thereof suitable for the pregnancy period Download PDF

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Publication number
CN110025529A
CN110025529A CN201910333111.7A CN201910333111A CN110025529A CN 110025529 A CN110025529 A CN 110025529A CN 201910333111 A CN201910333111 A CN 201910333111A CN 110025529 A CN110025529 A CN 110025529A
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Prior art keywords
solution
amino acid
pregnancy period
sodium
added
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Application number
CN201910333111.7A
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Chinese (zh)
Inventor
陈鑫隆
黄惠先
黄寿仙
江华初
陈云奇
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Guangzhou Cohen Biotechnology Co Ltd
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Guangzhou Cohen Biotechnology Co Ltd
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Priority to CN201910333111.7A priority Critical patent/CN110025529A/en
Publication of CN110025529A publication Critical patent/CN110025529A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/732Starch; Amylose; Amylopectin; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/002Preparations for repairing the hair, e.g. hair cure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/596Mixtures of surface active compounds

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cosmetics (AREA)

Abstract

A kind of mild shampoo and preparation method thereof suitable for the pregnancy period, is mainly compounded by amino acid surfactant with amphoteric surfactant, the hydrogenated starch hydrolysate and amino acid humectant for plant origin of arranging in pairs or groups are prepared;Preparation methods steps: (1) by water and cocounut oil acyl protein hydrolysate potassium, sodium lauroyl sarcosine, sodium cocoyl glutamate mixes to obtain solution A;(2) cocamidopropyl betaine is added into solution A, EDTA-2Na obtains solution B;(3) guar hydroxypropyltrimonium chloride is added into solution B, PEG-120 methyl dioleate and Polyquaternium-10 obtain solution C;(4) solution C is added hexylene glycol, parahydroxyacet-ophenone, rose wate, amino acid humectant, hydrogenated starch hydrolysate adjusts pH value and obtain finished product.The present invention has excellent characteristic of mildly releiving suitable for pregnant woman.

Description

A kind of mild shampoo and preparation method thereof suitable for the pregnancy period
Technical field
The present invention relates to wash shield product technical field more particularly to a kind of suitable for the mild shampoo in pregnancy period and its preparation Method.
Background technique
China shampoo market be personal care market development earliest, be at the soonest most hotly competitive market it One.Production firm faces more competitive pressure, releases product and the promotion method of various concept constantly to increase market Competitiveness.Shampoo type on the market is although multifarious, but the hair shampoo article in face of pregnant women it is few again It is few, declare individually shampoo suitable for the pregnancy period it is also most of be to be turned on concept, and remaining in the selection of formula material makes With laruyl alcohol sodium sulfovinate/laureth sodium sulfovinate etc., there is the surfactants of irritation hidden danger.The mother of pregnancy Because constitution and hormonal change, body are stronger to the susceptibility of climatic environment, usually some pinpricks on nursing product Just invite to obtain pregnancy mother's whole body itching.
It can be seen that how to face market needs to provide a kind of mild shampoo suitable for the pregnancy period, can really play Irritation potential problem is cleaned and is not present, this is the current technical issues that need to address in this field.
Summary of the invention
In view of the deficiencies of the prior art, this invention concept customized using private gene, according to different application on human skin bases Because of examining report, skin physiology, dermatopathology, skin situation, season, age, the dimension scientific design of region seven instantly Customize shampoo, accomplish flesh of more accurately taking care of hair, it is solved the technical issues of be irritation of the reduction shampoo to pregnant woman.
In order to solve the above technical problems, the technical solution adopted by the present invention is that a kind of mild shampoo suitable for the pregnancy period, It is made of following components mass percent: cocounut oil acyl protein hydrolysate potassium 2-6%, sodium lauroyl sarcosine 2-6%, cocounut oil acyl paddy ammonia Sour sodium 1-6%, cocamidopropyl betaine 1-6%, Polyquaternium-10 are 0.2~0.5%, PEG-120 methyl, two oil Acid esters 0.1~1%, guar hydroxypropyltrimonium chloride 0.1-0.5%, glycerol 1-5%, hexylene glycol 0.3-0.5%, to hydroxyl Benzoylformaldoxime 0.3-0.5%, rose wate 3-10%, amino acid humectant 0.2-1%, hydrogenated starch hydrolysate 0.1-1%, EDTA-2Na0.05-0.1% and water 70.9%-91.55%.
The amino acid humectant is made of following components mass percent: water 50.09%, Anjidew NL50 15%, sodium lactate 12%, arginine 8%, aspartic acid 5.2%, 2-pyrrolidone-5-carboxylic acid 4.27%, glycine 1.28%, alanine 1.2%, silk ammonia Sour 0.8%, valine 0.64%, proline 0.4%, threonine 0.4%, isoleucine 0.4%, histidine 0.16%, phenylpropyl alcohol Propylhomoserin 0.16%.
The invention solves another technical problem be to provide the preparation side of the above-mentioned mild shampoo suitable for the pregnancy period Method.
For this purpose, technical solution provided by the invention is a kind of preparation method of mild shampoo suitable for the pregnancy period, including Following steps:
(1) it adds water in reaction cylinder, adds cocounut oil acyl protein hydrolysate potassium, sodium lauroyl sarcosine, cocounut oil acyl glutamic acid Sodium is heated to 75~80 DEG C while stirring, is completely dissolved, obtains solution A;
(2) cocamidopropyl betaine, EDTA-2Na are added in Xiang Shangshu solution A, stirs evenly, is cooled to 70~75 DEG C, it is completely dissolved, obtains solution B;
(3) guar hydroxypropyltrimonium chloride, PEG-120 methyl dioleate are added in Xiang Shangshu solution B And Polyquaternium-10, it stirs evenly, is cooled to 55~65 DEG C, adds glycerol, stir evenly, be completely dissolved, obtain solution C;
(4) above-mentioned solution C is cooled to 35~45 DEG C, hexylene glycol, parahydroxyacet-ophenone, rose wate, amino acid is added Moisturizer, hydrogenated starch hydrolysate, while pH value is adjusted, continue to be uniformly mixed, is cooled to room temperature discharging, obtains finished product.
Further, the adjusting pH value is to adjust pH value to 5.5~6.5 using citric acid or sodium citrate.
Compared with prior art, the invention has the advantages that:
Amino acid surfactant has been selected to compound with amphoteric surfactant, not only foam is fine and closely woven also reduces system thorn Swash property;
There is the hydrogenated starch hydrolysate of plant origin skin to releive antipruritic effect;
Amino acid humectant increases hair moisture retention, enhance hair cardability and plentiful degree.
The present invention has good foaming, foam stability, cleans appropriateness and moisturizing effect;There is no because containing sulfate silicone oil, Stimulation potential problem caused by essence, hair after washing is submissive, flexible, cardability is good, safe nothing milder to skin Stimulation is suitable for pregnant women.
Specific embodiment
A specific embodiment of the invention is further described below with reference to embodiment, but is not to limit of the invention It is fixed.
Embodiment 1
A kind of mild shampoo suitable for the pregnancy period, is made of following components mass percent: cocounut oil acyl protein hydrolysate potassium 2%, sodium lauroyl sarcosine 2%, sodium cocoyl glutamate 3%, cocamidopropyl betaine 2%, Polyquaternium-10 are 0.5%, PEG-120 methyl dioleate 0.5%, guar hydroxypropyltrimonium chloride 0.3%, glycerol 2%, oneself two Alcohol 0.5%, parahydroxyacet-ophenone 0.5%, rose wate 5%, amino acid humectant 0.3%, hydrogenated starch hydrolysate 0.3%, EDTA-2Na 0.05%, water 81.05%.
Embodiment 2
A kind of mild shampoo suitable for the pregnancy period, is made of following components mass percent: cocounut oil acyl protein hydrolysate potassium 5%, sodium lauroyl sarcosine 3%, sodium cocoyl glutamate 3%, cocamidopropyl betaine 4%, Polyquaternium-10 are 0.5%, PEG-120 methyl dioleate 0.5%, guar hydroxypropyltrimonium chloride 0.3%, glycerol 2%, oneself two Alcohol 0.5%, parahydroxyacet-ophenone 0.5%, rose wate 8%, amino acid humectant 0.5%, hydrogenated starch hydrolysate 0.5%, EDTA-2Na 0.05%, water 71.65%.
Embodiment 3
A kind of mild shampoo suitable for the pregnancy period, is made of following components mass percent: cocounut oil acyl protein hydrolysate potassium 6%, sodium lauroyl sarcosine 6%, sodium cocoyl glutamate 6%, cocamidopropyl betaine 4%, Polyquaternium-10 are 0.5%, PEG-120 methyl dioleate 0.5%, guar hydroxypropyltrimonium chloride 0.3%, glycerol 2%, oneself two Alcohol 0.5%, parahydroxyacet-ophenone 0.5%, rose wate 10%, amino acid humectant 1%, hydrogenated starch hydrolysate 1%, EDTA-2Na 0.05%, water 61.65%.
1 to 3 preparation method of above-described embodiment, is made up of following steps:
(1) it adds water in reaction cylinder, adds cocounut oil acyl protein hydrolysate potassium, sodium lauroyl sarcosine, cocounut oil acyl glutamic acid Sodium is heated to 75~80 DEG C while stirring, is completely dissolved, obtains solution A;
(2) cocamidopropyl betaine, EDTA-2Na are added in Xiang Shangshu solution A, stirs evenly, is cooled to 70~75 DEG C, it is completely dissolved, obtains solution B;
(3) guar hydroxypropyltrimonium chloride, PEG-120 methyl dioleate are added in Xiang Shangshu solution B And Polyquaternium-10, it stirs evenly, is cooled to 55~65 DEG C, adds glycerol, stir evenly, be completely dissolved, obtain solution C;
(4) above-mentioned solution C is cooled to 35~45 DEG C, hexylene glycol, parahydroxyacet-ophenone, rose wate, amino acid is added Moisturizer, hydrogenated starch hydrolysate, while pH value is adjusted, continue to be uniformly mixed, is cooled to room temperature discharging, obtains finished product.
Further, the adjusting pH value is to adjust pH value to 5.5~6.5 using citric acid or sodium citrate.
Beneficial effect in order to better illustrate the present invention carries out efficacy assessments experiment:
Experimental group: pregnant women 50 between 25-40 years old of selection age are randomly divided into two groups, and each group is in year It records, no significant difference on hair quality, first group of present invention made using the present embodiment, second group available using the market money pregnancy period Shampoo.
The application method of shampoo:
It takes after hair is drenched and is uniformly applied on head after the palm of the hand, rubbing blistering in right amount, gently rubbed from root of hair to the hair tip After rubbing with the hands 2-3 minutes, rinsed well with clear water.
Test result
As a result statistics carries out comprehensive score using investigation point system, washes a hair within every group of crowd every 2 days, continuously washes 15 It, fills in using assessment table.Every using effect total score is 10 points in grade form, and 9-10 points indicate that effect is optimal, and 7-8 points indicate Preferably, 5-6 point indicates general, 4 points and following presentation it is poor.Every using effect average situation is as shown in table 1 below:
Table 1
Test result statistics is as shown above, in scalp clean-up performance and to gap both in hair quality compliance improvement degree Less, but scalp and to scalp irritation this two embodied critical function index of the invention, the present invention is surveying Examination example in without occur itch stimulation phenomenon, and in second group of test group using the market pregnancy period can use shampoo occur two heads Skin itch situation, in contrast, the mild shampoo for being used in pregnant women of the invention have excellent scalp of releiving, mildly Inirritative effect.
Detailed description is made that embodiments of the present invention in conjunction with the embodiments above, but the present invention be not limited to it is described Embodiment.To those skilled in the art, without departing from the principles and spirit of the present invention, to these realities The mode of applying carries out various change, modification, replacement and variant are still fallen in protection scope of the present invention.

Claims (5)

1. a kind of mild shampoo suitable for the pregnancy period, which is characterized in that be made of following components mass percent: cocounut oil acyl water Solve albumen potassium 2-6%, sodium lauroyl sarcosine 2-6%, sodium cocoyl glutamate 1-6%, cocamidopropyl betaine 1- 6%, Polyquaternium-10 is 0.2~0.5%, PEG-120 methyl dioleate 0.1~1%, melon rubber hydroxypropyl trimethylammonium Ammonium chloride 0.1-0.5%, glycerol 1-5%, hexylene glycol 0.3-0.5%, parahydroxyacet-ophenone 0.3-0.5%, rose wate 3- 10%, amino acid humectant 0.2-1%, hydrogenated starch hydrolysate 0.1-1%, EDTA-2Na 0.05-0.1% and water 70.9%- 91.55%.
2. the mild shampoo according to claim 1 suitable for the pregnancy period, which is characterized in that by following components quality percentage Than being made: cocounut oil acyl protein hydrolysate potassium 5%, sodium lauroyl sarcosine 3%, sodium cocoyl glutamate 3%, cocamidopropyl sweet tea Dish alkali 4%, Polyquaternium-10 0.5%, PEG-120 methyl dioleate 0.5%, melon rubber Hydroxyproyl Trimethyl chlorine Change ammonium 0.3%, glycerol 2%, hexylene glycol 0.5%, parahydroxyacet-ophenone 0.5%, rose wate 8%, amino acid humectant 0.5%, hydrogenated starch hydrolysate 0.5%, EDTA-2Na 0.05%, water 71.65%.
3. the mild shampoo according to claim 1 or 2 suitable for the pregnancy period, which is characterized in that the amino acid moisturizing Agent is made of following components mass percent: water 50.09%, Anjidew NL50 15%, sodium lactate 12%, arginine 8%, aspartic acid 5.2%, 2-pyrrolidone-5-carboxylic acid 4.27%, glycine 1.28%, alanine 1.2%, serine 0.8%, valine 0.64%, dried meat Propylhomoserin 0.4%, threonine 0.4%, isoleucine 0.4%, histidine 0.16%, phenylalanine 0.16%.
4. a kind of preparation method suitable for the mild shampoo in pregnancy period as claimed in claim 1 or 2, which is characterized in that packet Include following steps:
(1) it adds water in reaction cylinder, adds cocounut oil acyl protein hydrolysate potassium, sodium lauroyl sarcosine, sodium cocoyl glutamate, side Stirring side is heated to 75~80 DEG C, is completely dissolved, obtains solution A;
(2) cocamidopropyl betaine, EDTA-2Na are added in Xiang Shangshu solution A, stirs evenly, is cooled to 70~75 DEG C, It is completely dissolved, obtains solution B;
(3) it is added guar hydroxypropyltrimonium chloride in Xiang Shangshu solution B, PEG-120 methyl dioleate and poly- Quaternary ammonium salt -10, stirs evenly, and is cooled to 55~65 DEG C, adds glycerol, stir evenly, be completely dissolved, obtains solution C;
(4) above-mentioned solution C is cooled to 35~45 DEG C, hexylene glycol, parahydroxyacet-ophenone, rose wate, amino acid moisturizing is added Agent, hydrogenated starch hydrolysate, while pH value is adjusted, continue to be uniformly mixed, is cooled to room temperature discharging, obtains finished product.
5. a kind of preparation method suitable for the mild shampoo in pregnancy period as claimed in claim 4, which is characterized in that step (4) in, the adjusting pH value is to adjust pH value to 5.5~6.5 using citric acid or sodium citrate.
CN201910333111.7A 2019-04-24 2019-04-24 A kind of mild shampoo and preparation method thereof suitable for the pregnancy period Withdrawn CN110025529A (en)

Priority Applications (1)

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CN201910333111.7A CN110025529A (en) 2019-04-24 2019-04-24 A kind of mild shampoo and preparation method thereof suitable for the pregnancy period

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Application Number Priority Date Filing Date Title
CN201910333111.7A CN110025529A (en) 2019-04-24 2019-04-24 A kind of mild shampoo and preparation method thereof suitable for the pregnancy period

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CN110025529A true CN110025529A (en) 2019-07-19

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110897988A (en) * 2019-12-17 2020-03-24 湖北省麦诗特生物科技有限公司 Hair-strengthening and hair-nourishing amino acid shampoo containing sturgeon roe extract liposome and preparation method thereof
CN112426375A (en) * 2020-12-15 2021-03-02 金发拉比妇婴童用品股份有限公司 Maltose shampoo

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110897988A (en) * 2019-12-17 2020-03-24 湖北省麦诗特生物科技有限公司 Hair-strengthening and hair-nourishing amino acid shampoo containing sturgeon roe extract liposome and preparation method thereof
CN110897988B (en) * 2019-12-17 2022-05-03 湖北省麦诗特生物科技有限公司 Hair-strengthening and hair-nourishing amino acid shampoo containing sturgeon roe extract liposome and preparation method thereof
CN112426375A (en) * 2020-12-15 2021-03-02 金发拉比妇婴童用品股份有限公司 Maltose shampoo
CN112426375B (en) * 2020-12-15 2023-02-17 金发拉比妇婴童用品股份有限公司 Maltose shampoo

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Application publication date: 20190719

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