CN110022907A - 非细胞毒性的修饰细胞及其用途 - Google Patents

非细胞毒性的修饰细胞及其用途 Download PDF

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CN110022907A
CN110022907A CN201780074816.0A CN201780074816A CN110022907A CN 110022907 A CN110022907 A CN 110022907A CN 201780074816 A CN201780074816 A CN 201780074816A CN 110022907 A CN110022907 A CN 110022907A
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A·蒙索戈
A·波加多
R·阿特拉斯
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National Institute for Biotechnology in the Negev Ltd
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
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CN201780074816.0A 2016-10-10 2017-10-10 非细胞毒性的修饰细胞及其用途 Pending CN110022907A (zh)

Applications Claiming Priority (3)

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US201662406005P 2016-10-10 2016-10-10
US62/406,005 2016-10-10
PCT/IL2017/051133 WO2018069927A1 (en) 2016-10-10 2017-10-10 Non-cytotoxic modified cells and use thereof

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CN110022907A true CN110022907A (zh) 2019-07-16

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US (2) US12098202B2 (enExample)
EP (1) EP3522936A4 (enExample)
JP (1) JP7213799B2 (enExample)
CN (1) CN110022907A (enExample)
AU (1) AU2017342176A1 (enExample)
CA (1) CA3039774A1 (enExample)
IL (1) IL265962B2 (enExample)
WO (1) WO2018069927A1 (enExample)

Cited By (2)

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CN113490517A (zh) * 2021-04-27 2021-10-08 北京博辉瑞进生物科技有限公司 一种嵌合肽修饰的sis膜、其制备方法及应用
CN117736329A (zh) * 2023-12-25 2024-03-22 华润生物医药有限公司 抗pd-1抗体及其用途

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JP7193628B2 (ja) * 2018-07-06 2022-12-20 北京天成新脉生物技▲術▼有限公司 低ａｄｃｃ／ｃｄｃ機能性モノクローナル抗体、及びその調製方法と使用
BR112021013008A2 (pt) * 2019-01-11 2021-11-23 Wistar Inst Composição para gerar um ou mais anticorpos antiproteína de morte celular programada 1 (pd-1) ou fragmentos dos mesmos, método para tratar uma doença, e, método para aumentar uma resposta imune

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