CN110012661A - 普利多匹定用于治疗肌张力障碍的用途 - Google Patents

普利多匹定用于治疗肌张力障碍的用途 Download PDF

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Publication number
CN110012661A
CN110012661A CN201780066796.2A CN201780066796A CN110012661A CN 110012661 A CN110012661 A CN 110012661A CN 201780066796 A CN201780066796 A CN 201780066796A CN 110012661 A CN110012661 A CN 110012661A
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CN
China
Prior art keywords
myodystony
dystonia
twice daily
subject
pridopidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201780066796.2A
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English (en)
Chinese (zh)
Inventor
迈克尔·海登
史派瑞顿·帕帕佩特罗普洛斯
尤哈-马蒂·萨福拉
伊莱·埃亚勒
贝丝·博罗夫斯基
伊戈尔·D·格拉切夫
马克·福勒斯特·戈登
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Prinia Medical Development Co Ltd
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Prinia Medical Development Co Ltd
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Application filed by Prinia Medical Development Co Ltd filed Critical Prinia Medical Development Co Ltd
Publication of CN110012661A publication Critical patent/CN110012661A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201780066796.2A 2016-08-24 2017-08-24 普利多匹定用于治疗肌张力障碍的用途 Pending CN110012661A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662379175P 2016-08-24 2016-08-24
US62/379,175 2016-08-24
US201662395319P 2016-09-15 2016-09-15
US62/395,319 2016-09-15
PCT/US2017/048458 WO2018039475A1 (en) 2016-08-24 2017-08-24 Use of pridopidine for treating dystonias

Publications (1)

Publication Number Publication Date
CN110012661A true CN110012661A (zh) 2019-07-12

Family

ID=61246309

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780066796.2A Pending CN110012661A (zh) 2016-08-24 2017-08-24 普利多匹定用于治疗肌张力障碍的用途

Country Status (12)

Country Link
US (2) US11826361B2 (OSRAM)
EP (1) EP3503890B1 (OSRAM)
JP (2) JP7278210B2 (OSRAM)
CN (1) CN110012661A (OSRAM)
AU (1) AU2017315781B2 (OSRAM)
BR (1) BR112019003731A2 (OSRAM)
CA (1) CA3035099C (OSRAM)
DK (1) DK3503890T3 (OSRAM)
ES (1) ES3009437T3 (OSRAM)
MX (1) MX2019002190A (OSRAM)
PL (1) PL3503890T3 (OSRAM)
WO (1) WO2018039475A1 (OSRAM)

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US11090297B2 (en) 2013-06-21 2021-08-17 Prilenia Neurotherapeutics Ltd. Pridopidine for treating huntington's disease
US11471449B2 (en) 2015-02-25 2022-10-18 Prilenia Neurotherapeutics Ltd. Use of pridopidine to improve cognitive function and for treating Alzheimer's disease
EP3590512A1 (en) 2015-02-25 2020-01-08 Prilenia Neurotherapeutics Ltd. Use of pridopidine to treat epilepsy
JP6912574B2 (ja) 2016-08-24 2021-08-04 プリレニア ニューロセラピューティクス リミテッド 機能低下を治療するためのプリドピジンの使用
BR112019003731A2 (pt) 2016-08-24 2019-07-16 Prilenia Therapeutics Dev Ltd aplicação de pridopidina para tratamento de distonias
US12102627B2 (en) 2016-09-16 2024-10-01 Prilenia Neurotherapeutics Ltd. Use of pridopidine for treating rett syndrome
US12036213B2 (en) 2017-09-08 2024-07-16 Prilenia Neurotherapeutics Ltd. Pridopidine for treating drug induced dyskinesias
MX383462B (es) 2017-09-08 2025-03-14 Prilenia Neurotherapeutics Ltd Pridopidina para el tratamiento de las discinesias inducidas por fármacos
US12357624B2 (en) 2019-02-04 2025-07-15 Prilenia Neurotherapeutics Ltd. Low dose pridopidine for Parkinson's Disease and other diseases associated with parkinsonism
BR112022022427A2 (pt) * 2020-05-04 2022-12-13 Prilenia Neurotherapeutics Ltd Tratamento de infecção, doença ou distúrbio viral com o uso de um agonista de s1r seletivo
AU2023420087A1 (en) * 2022-12-27 2025-07-10 Prilenia Neurotherapeutics Ltd. Pridopidine for treating juvenile huntington's disease
WO2024258929A1 (en) * 2023-06-12 2024-12-19 Unravel Biosciences, Inc. Methods for treating diseases associated with taf1 loss of function
US20250281500A1 (en) * 2024-03-06 2025-09-11 Ovid Therapeutics Inc. Fused amino pyrimidine compounds and pridopidine for treatment of huntington’s disease

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US20130150406A1 (en) * 2011-12-08 2013-06-13 IVAX International GmbH Hydrobromide salt of pridopidine
US20150202302A1 (en) * 2014-01-22 2015-07-23 IVAX International GmbH Modified release formulations of pridopidine
CN105592848A (zh) * 2013-06-21 2016-05-18 梯瓦制药国际有限责任公司 高剂量普利多匹定用于治疗亨廷顿舞蹈症的用途

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EA201390332A1 (ru) 2010-09-03 2013-08-30 Ивакс Интернэшнл Гмбх Дейтерированные аналоги придопидина, применимые в качестве допаминергических стабилизаторов
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EA027748B1 (ru) 2012-04-04 2017-08-31 Тева Фармасьютикалз Интернэшнл Гмбх Применение придопидина в комбинации с тетрабеназином для лечения двигательных нарушений и ожирения
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BR112019003731A2 (pt) 2016-08-24 2019-07-16 Prilenia Therapeutics Dev Ltd aplicação de pridopidina para tratamento de distonias
JP6912574B2 (ja) 2016-08-24 2021-08-04 プリレニア ニューロセラピューティクス リミテッド 機能低下を治療するためのプリドピジンの使用
JP2019529411A (ja) 2016-09-15 2019-10-17 プリレニア ニューロセラピューティクス リミテッド 不安症およびうつ病の治療のためのプリドピジンの使用
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US20130150406A1 (en) * 2011-12-08 2013-06-13 IVAX International GmbH Hydrobromide salt of pridopidine
CN105592848A (zh) * 2013-06-21 2016-05-18 梯瓦制药国际有限责任公司 高剂量普利多匹定用于治疗亨廷顿舞蹈症的用途
US20150202302A1 (en) * 2014-01-22 2015-07-23 IVAX International GmbH Modified release formulations of pridopidine

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Also Published As

Publication number Publication date
AU2017315781B2 (en) 2021-01-28
MX2019002190A (es) 2019-09-11
DK3503890T3 (da) 2025-01-27
JP2021119189A (ja) 2021-08-12
WO2018039475A1 (en) 2018-03-01
JP7278210B2 (ja) 2023-05-19
CA3035099A1 (en) 2018-03-01
BR112019003731A2 (pt) 2019-07-16
JP7278327B2 (ja) 2023-05-19
AU2017315781A1 (en) 2019-04-11
US20190192496A1 (en) 2019-06-27
PL3503890T3 (pl) 2025-03-24
CA3035099C (en) 2023-01-17
EP3503890A1 (en) 2019-07-03
EP3503890A4 (en) 2020-05-06
US20240075021A1 (en) 2024-03-07
WO2018039475A8 (en) 2018-10-04
US11826361B2 (en) 2023-11-28
JP2019524897A (ja) 2019-09-05
ES3009437T3 (en) 2025-03-26
EP3503890B1 (en) 2024-12-18

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Address after: Herzliya

Applicant after: Prinia Neuropathy Co., Ltd.

Address before: Herzliya

Applicant before: Prinia Medical Development Co., Ltd.