CN109998009A - A kind of solid beverage of Chinese chestnut peptide and preparation method thereof - Google Patents
A kind of solid beverage of Chinese chestnut peptide and preparation method thereof Download PDFInfo
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- CN109998009A CN109998009A CN201811183616.1A CN201811183616A CN109998009A CN 109998009 A CN109998009 A CN 109998009A CN 201811183616 A CN201811183616 A CN 201811183616A CN 109998009 A CN109998009 A CN 109998009A
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- chinese chestnut
- peptide
- temperature
- ginsenoside
- preparation
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- 210000003171 tumor-infiltrating lymphocyte Anatomy 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 230000029812 viral genome replication Effects 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 230000010294 whole body metabolism Effects 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/006—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from vegetable materials
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
- A23L2/39—Dry compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids
Abstract
The invention discloses a kind of solid beverages, especially a kind of solid beverage of Chinese chestnut peptide, the weight percent group ratio of raw material are as follows: Chinese chestnut peptide 80-90%, ginsenoside 5-8%, curcumin 2-5%, pachymaran 1-3%, Schisandra chinens P.E 1-3% and chrysanthemum extract 0.5-1.5%.Meanwhile a kind of preparation method of the solid beverage of above-mentioned Chinese chestnut peptide is additionally provided in the present invention.A kind of solid beverage for Chinese chestnut peptide that the present invention obtains, facilitate repair enteron aisle, it is aid digestion, help for sleep, lower hyperlipidemia, hypertension, hyperglycemia strengthening spleen, tonifying kidney, is promoted longevity, salubrity solid；Meanwhile the preparation method of the solid beverage of one of present invention Chinese chestnut peptide, high with simple process, recovery rate, the significant advantage of good product quality, comprehensive benefit is suitable for factory's expanded production.
Description
Technical field
The present invention relates to a kind of solid beverage and preparation method thereof, the solid beverage of especially a kind of Chinese chestnut peptide and its preparation
Method.
Background technique
Chinese chestnut is perennial deciduous fruit tree arbor, is called great Li, stalwart chestnut.Fruits in Chinese Chestnut is full of nutrition, containing shallow lake in every 100 grams
Powder 51-60%, protein 5.7-10.7%, fatty 2-7.4%, 15 milligrams of calcium, 1.2 milligrams of iron, 1.32 milligrams of zinc, vitamin
E11.45 milligrams, 0.15 milligram of riboflavin .5 milligrams of Catergen, crude fibre, carrotene, vitamin A, B, C and calcium, phosphorus, potassium
Equal minerals, are up to 98% for absorption of human body and the nutritional ingredient utilized.
Although Chinese chestnut has very high medical value and nutriment rich in, since it contains a large amount of shallow lake
Powder and carbohydrate are difficult to be digested, especially diabetes patient, and overeating influences the stabilization of blood glucose.
Past scientific research thinks that protein is mainly absorbed in the form of amino acid after alimentary canal enzymatic hydrolysis.
Nearly scientific research in 2 years thinks that the principal mode of absorption of human body protein not instead of amino acid is absorbed in the form of polypeptide
, this is the important breakthrough of absorption of human body protein Mechanism Study.Scientific experimentation proves that the mechanism of absorption of polypeptide shows several big
Feature:
1., be not required to digest, directly absorb.The polypeptide of human body itself synthesis, which is human body, carries out protein obtained by enzymatic hydrolysis (by
Promote enzyme, digestive ferment, pancreatin, pepsin, gastric acid, alimentary canal alkaline matter to be decomposed, some is broken down into small peptide, some quilts
It is decomposed into amino acid residue, some is broken down into free amino acid, and small peptide is absorbed eventually by small intestine, then thin through human body
Born of the same parents, tissue, organ and blood systemic circulation).And there is layer protecting film on external artificial synthesized small peptide surface, after being taken by human body not
It will receive various enzymes and the secondary hydrolysis of acid-base material of human body, it is directly entered small intestine as the peptide of human body synthesis, by small intestine
It is absorbed, into human recycle system, plays biological function.
2., absorb it is quick.The polypeptide synthesized outside prosthesis takes orally and enters human body, it fast compared with amino acid 70% speed, fastly
Fastly across the oral cavity of people, stomach, it is directly entered small intestine, by small intestinal absorption, eventually enters into blood circulation of human body system, organ and thin
Born of the same parents' tissue, plays rapidly its physiological action and biological function.
3., in the form of complete absorb.Polypeptide is absorbed and utilized by the body in the form of complete.
4., polypeptide have the characteristics that 100% is absorbed by the body.After absorption, any excreta is not had, and is whole quilts
Absorption of human body and utilization.
5., polypeptide have the characteristics that actively be absorbed by the body.For because of digestive system defect, obstacle, damage, and cannot inhale
Receive nutrition person, polypeptide, which has the characteristics that actively to allow, absorption of human body or forces absorption of human body.This, nutrition poor for those digestion powers
Lack, person in poor health, has great significance.
6., polypeptide has the characteristics that preferentially to be absorbed by the body.Nutriment and the human body degradation that people are eaten usually
In amino acid residue and amino acid, with the absorption competition of polypeptide, polypeptide has the characteristics that preferential absorption.This is actively absorbed from the gastrointestinal tract with it
The characteristics of be undivided.
7., absorption of the human body to polypeptide, have be not required to expend body energy, be not required to increase alimentary canal, especially stomach and intestine function
The characteristics of capable of bearing.There is polypeptide itself extremely strong activity and energy, its active absorption to force absorption, be exactly the work of itself
Property and energy are in action.Therefore, it when being absorbed by the body, the energy that instead of human body does not expend itself goes to absorb it, more
Peptide is with the energy of itself by absorption of human body.Its this distinguishing feature is to the infant of digestive system undeveloped mature, to digestion
System start degenerate the elderly and because overexercise be badly in need of nitrogen source, and not can increase gastrointestinal function burden sportsman,
Physical labourer's important in inhibiting.
8., polypeptide show carrier function in human body, the nutriment that can be eaten mediocrity, especially calcium etc. is to people
The beneficial microelement of body, absorption are pasted, are loaded on the body.
9., polypeptide can play means of transport in human body.Various nutriments can be adsorbed and be transported afterwards on the body
It to each cell of human body, organ, tissue, is absorbed and utilized by the body together with ontology, plays respectively different functions.This
It is exactly that for people using polypeptide raw material midbody as the reason of drug and food formula, its purpose is to reinforce drug effect in the world at present
And enriched nutritive, enhance human body to its absorptivity.
10., after polypeptide is absorbed by the body, courier can be played in human body.It transmits the letter of information as neurotransmitter
Make, commander nerve, play self-acting, safeguard the team spirit and group effect of human nerve, make human body become it is more flexible,
It is sensitive, wise.
Summary of the invention
A kind of solid beverage of Chinese chestnut peptide is provided the purpose of the present invention is to solve above-mentioned the deficiencies in the prior art.
To achieve the goals above, the solid beverage of a kind of Chinese chestnut peptide designed by the present invention, the weight percent of raw material
Group ratio are as follows: Chinese chestnut peptide 80-90%, ginsenoside 5-8%, curcumin 2-5%, pachymaran 1-3%, Schisandra chinens P.E 1-3% and chrysanthemum
Flower extract 0.5-1.5%.
A kind of preparation method of the solid beverage of Chinese chestnut peptide is provided in the present invention simultaneously comprising following step:
A, the preparation of Chinese chestnut peptide
Chinese chestnut Seed after cleaning is placed in the VC solution or citric acid solution of color protection and impregnates 3-6h, then grinds slurrying；It will
Slurries are 130-135 DEG C in temperature, and mill pressure processing under 6-8 atmospheric pressure, fineness of grind is 120-160 mesh, then passes through 120-150
DEG C ultra high temperature short time sterilization processing, after be cooled to 30-55 DEG C；It is added in slurries after sterilization and accounts for weight of material 1.0-1.5%
Carbohydrase in slurries chestnut starch saccharification handle, time 3-4.5h, temperature be 30-40 DEG C；By the slurries after saccharification
Be heated to 80-100 DEG C of progress destroy the enzyme treatment, after be cooled to 25-40 DEG C, then be then added with hydrochloric acid adjustment pH value to 3.5-5.5
It accounts for the acid protease of weight of material 0.5-2.5% and the lipase of 0.1-0.15% and carries out that 5-10min is sufficiently stirred, it is rear to carry out
Constant temperature stands 12-15h and carries out biochemical degradation condensation；The supernatant obtained after biochemical degradation is condensed extracts, then passes through 90-
Destroy the enzyme treatment under the conditions of 105 DEG C, then refined filtration obtains Chinese chestnut peptide stoste, and Chinese chestnut Gly-His-Lys are made after concentration；
B, the preparation of ginsenoside
Ginseng is cleaned into slice, the distilled water for accounting for weight of material 50-55% is added and is stirred evenly, mixing time 1-3h；By even liquid
It is 60-75 DEG C in temperature, mill pressure processing under 3-5 atmospheric pressure, fineness of grind is 100-150 mesh；Add fermenting microbe into even liquid
Fermentation；Fermentation liquid is imported in extraction kettle, supercritical CO is used2As extractant, beeswax is as entrainer, in extraction temperature
Under 20-25 DEG C, Fluid pressure 25-35MPa, flow velocity 0.1-0.4ml/min, extraction 1-3h obtains extract, extract second
Alcohol absorbs to obtain concentration absorbing liquid；It is concentrated in absorbing liquid onto the pillar equipped with macroporous absorbent resin, applied sample amount is weight resin
The concentration absorbing liquid of equivalent, loading flow control is in 2 bed volumes per hour；With the ethyl alcohol analytic tree of mass fraction 65-75%
The ginsenoside effective component of rouge absorption, elution liquid measure are 6-7 times of weight resin, and elution flow rate is controlled in 1-1.2 per hour
A bed volume collects to obtain ginsenoside eluent；Ginsenoside eluent is put into bleacher, it is corresponding that eluent is added
The magnesia of equivalent gen-seng haulms raw material weight 10% is stirred reflux decoloration 1-1.5h, then carries out plate-frame filtering, washing,
It collects to merge and obtains magnesia decolorization filtering liquid and cleaning solution；It is dense that magnesia decolorization filtering liquid and cleaning solution are subjected to vacuum decompression
Contracting, thickening temperature≤80 DEG C are concentrated vacuum degree≤- 0.08MPa, are concentrated into condensed cream specific gravity 1.1-1.15, rear to be spray-dried, i.e.,
Obtain ginsenoside powder；
C, the preparation of curcumin
It will be granulated under conditions of logical steam after curcuma grinds, granularity is 30-60 mesh；Gained after being granulated
Grain is extracted with leaching liquor, and leaching liquor is ethyl alcohol；It in temperature is 100-110 DEG C by extracting solution, mill pressure is handled under 5-7 atmospheric pressure,
Fineness of grind is 90-150 mesh to get curcumin powder；
D, the preparation of pachymaran
Poria cocos is crushed and screened into 20 mesh coarse powder, 5-10 times of distilled water is then added, ultrasound adverse current heating is boiled 1.5-2h, mentioned
It takes 4 times；Extracting solution is subjected to separation, impurity removal, merging filtrate by centrifuge；Filtrate is with microfiltration membranes PP cotton coarse filtration, coarse filtration temperature
25-35 DEG C, pressure 0.1-0.5Mpa；It is the polysulfone hollow fibre of 10000 dalton by coarse filtration filtrate nominal molecular cut off
Formula ultrafiltration membrane (UF) further refined filtration, 25-35 DEG C of refined filtration temperature, pressure 0.05-0.1Mpa；By refined filtration filtrate temperature be 35-
45 DEG C, mill pressure processing under 8-9 atmospheric pressure, fineness of grind is 100-130 mesh, then is done by way of vacuum freeze drying
It is dry to get arrive pachymaran powder；
E, by above-mentioned Chinese chestnut Gly-His-Lys, ginsenoside powder, curcumin powder and pachymaran powder, then it is subject to Schisandra chinens P.E and chrysanthemum
Extract is mixed to arrive the solid beverage of Chinese chestnut peptide；The wherein weight percent group ratio of raw material are as follows: Chinese chestnut peptide 80-90%,
Ginsenoside 5-8%, curcumin 2-5%, pachymaran 1-3%, Schisandra chinens P.E 1-3% and chrysanthemum extract 0.5-1.5%.
Preferably, curcuma described in above-mentioned steps c includes one or more of turmeric, curcuma zedoary and Radix Curcumae.
Chinese chestnut peptide is a kind of novel polypeptide in present component, has antibacterial, antitumor, enhancing conventional antibiotic to resistance to
The activity of medicine bacterium promotes the multinomial biological functions such as wound healing.There is strong antibacterial activity, has a broad antifungal spectrum, bacterium to be not easy to produce for it
The features such as raw tolerance.It actively can quickly be absorbed by human body in the form of complete.
Ginsenoside is a kind of steroid compound, triterpenoid saponin in present component.It is primarily present in Panax medicinal material
In.Ginsenoside is considered to be the active constituent in ginseng, and efficiency is as follows: 1. tonifying Qi emergency treatment of collapse: supplement vigour, slow to various urgency
Property disease caused by physical strength it is weak or temporary collapse it is effective, it can promote physical strength；2. beneficial blood answers arteries and veins: promoting blood raw
At, promote lung splenic function, whole body metabolism caused by improving because of anaemia, while with hematopoiesis and blood circulation can be promoted；3. supporting
Heart and tranquilizing mind: calming nerves of feeling at ease, mitigate due to blood have some setbacks or heart function decline caused by spirit uneasiness；4. promoting the production of body fluid to quench thirst:
Improve the function of lung, spleen, stomach, promotes physical efficiency；Ginseng can serve as the necessary body fluid of human body, to mitigate thirsty symptom, i.e.,
It is effective to treatment diabetes；5. tonifying spleen Dingchuan: it is effective to the symptoms such as wheeze and cough caused by decline in pulmonary function, pass through enhancement
The function supplement vital essence of spleen, stomach, the i.e. illness by stablizing respiratory therapy respiratory system；6. invigorating the spleen to arrest diarrhea: strengthening intestinal tube, stop
It rushes down, strengthens digestive organs, with aid digestion；7. eliminating toxic close sore: reject vivotoxin, to degenerating because of metabolism caused by disease it is strong
Change resistance, makes skin function normalization, it is also effective to tumour.
Curcumin has effects that following in present component: 1. anti-inflammatory activity: curcumin is to acute, subacute and chronic
Inflammation has anti-inflammatory effect；Curcumin mainly stimulates cortin to increase, while inhibiting the formation of neutrophil leucocyte leukotriene, subtracts
Neutrophil infiltration in light tissue, so as to improve its lesion degree；2. effect for reducing blood fat: it is solid that curcumin can reduce total gallbladder in blood
Alcohol, triglycerides (TG) are horizontal, it is horizontal to improve aPoA, and reduce lipid peroxide in blood and liver, promote liver and adrenal gland
Metabolism to low-density lipoprotein (LDL) and lipoprotein (a) increases gall-bladder and drains to LDL, inhibits intake of the spleen to LDL, makes blood
The content of middle LDL and lipoprotein (a) reduces, to play the role of reducing blood lipid and antiatherosclerosis；3. improving heart function
Can: curcumin can make isoprel induction myocardial ischemia sexually revise mitigation, myocardial hypoxia tolerance also can be improved, to cardiac muscle
Ischemia injury have certain protective effect；4. resisting HIV acts on: curcumin has antiviral activity,
Main active, the relevant protease of suppressing virus replication by inhibition human immunodeficiency virus (H IV) long terminal repeats,
To play inhibiting effect to HIV；5. the protective effect to liver: turmeric and curcumin in vivo and in vitro to various poisonous substances such as
Carbon tetrachloride, aflatoxin B1, paracetamol, iron and the hepatic injury of cyclophosphamide induction have protective effect；It can inhibit
The inhibition from mutation rate of aflatoxin B1 inducible strain thyph/mur/um detection of Salmonella TA98 and TAl00 are more than 80%；6. to kidney
Protective effect: the renal damage and ischemia-reperfusion renal damage that curcumin induces the renal damage of caused by doxorubicin, oxidative stress
All have protective effect；7. anti-fibrosis effect: curcumin can obviously inhibit the total number of cells of bronchovesicular, total protein concentration,
Angiotensin-Converting content and alkaline phosphatase activities, it may be a kind of for no matter prompting curcumin in vivo or in vitro
Anti fibrosis；8. cancer-resisting acts on: curcumin reduces nitrous acid category compound by keeping nitrite anions ineffective
It is formed and plays protective effect on cancer risk；9. inhibiting tumor cell proliferation: curcumin can also make kinds of tumor cells be gathered in the S phase, cannot
It is significantly inhibited into next cell generation cycle, is in dose-effect relationship；10. inducing tumour cell
Apoptosis: its lethal effect of curcumin is more sensitive to tumor proliferation phase cell, and it is non-to belong to advantage killing proliferation period Cell Cycle
Specific Anti-Cancer medicine, inducing apoptosis of tumour cell are its important role modes；Improve immunologic cellular activity: curcumin can also be bright
It is aobvious to improve natural killer cells, Tumor-infiltrating lymphocytes activity, increase the number of CIM+, CD8+ cell in spleen, from
And adjust cellular immune function.
Chinese chestnut Gly-His-Lys, ginsenoside powder and pachymaran powder in present component, then it is subject to Schisandra chinens P.E and chrysanthemum
Extract is mixed, and reaches nutrition complement, prominent is the effect of peptide and small molecular organic acid that human body directly absorbs.
A kind of solid beverage for Chinese chestnut peptide that the present invention obtains, facilitate repair enteron aisle, it is aid digestion, help for sleep, drop
Three height strengthening spleen, tonifying kidney, are promoted longevity, salubrity solid.Meanwhile the preparation side of the solid beverage of one of present invention Chinese chestnut peptide
Method, high with simple process, recovery rate, the significant advantage of good product quality, comprehensive benefit is suitable for factory and expands metaplasia
It produces.
Specific embodiment
Below with reference to embodiment, the present invention is further described.
Embodiment 1:
A kind of solid beverage of Chinese chestnut peptide provided in this embodiment, the weight percent group ratio of raw material are as follows: Chinese chestnut peptide 80%, ginseng
Saponin(e 8%, curcumin 5%, pachymaran 3%, Schisandra chinens P.E 3% and chrysanthemum extract 1%.
A kind of preparation method of the solid beverage of above-mentioned Chinese chestnut peptide comprising following step:
A, the preparation of Chinese chestnut peptide
Chinese chestnut Seed after cleaning is placed in the VC solution or citric acid solution of color protection and impregnates 3-6h, then grinds slurrying；It will
Slurries are 130-135 DEG C in temperature, and mill pressure processing under 6-8 atmospheric pressure, fineness of grind is 120-160 mesh, then passes through 120-150
DEG C ultra high temperature short time sterilization processing, after be cooled to 30-55 DEG C；It is added in slurries after sterilization and accounts for weight of material 1.0-1.5%
Carbohydrase in slurries chestnut starch saccharification handle, time 3-4.5h, temperature be 30-40 DEG C；By the slurries after saccharification
Be heated to 80-100 DEG C of progress destroy the enzyme treatment, after be cooled to 25-40 DEG C, then be then added with hydrochloric acid adjustment pH value to 3.5-5.5
It accounts for the acid protease of weight of material 0.5-2.5% and the lipase of 0.1-0.15% and carries out that 5-10min is sufficiently stirred, it is rear to carry out
Constant temperature stands 12-15h and carries out biochemical degradation condensation；The supernatant obtained after biochemical degradation is condensed extracts, then passes through 90-
Destroy the enzyme treatment under the conditions of 105 DEG C, then refined filtration obtains Chinese chestnut peptide stoste, and Chinese chestnut Gly-His-Lys are made after concentration；
B, the preparation of ginsenoside
Ginseng is cleaned into slice, the distilled water for accounting for weight of material 50-55% is added and is stirred evenly, mixing time 1-3h；By even liquid
It is 60-75 DEG C in temperature, mill pressure processing under 3-5 atmospheric pressure, fineness of grind is 100-150 mesh；Add fermenting microbe into even liquid
Fermentation；Fermentation liquid is imported in extraction kettle, supercritical CO is used2As extractant, beeswax is as entrainer, in extraction temperature
Under 20-25 DEG C, Fluid pressure 25-35MPa, flow velocity 0.1-0.4ml/min, extraction 1-3h obtains extract, extract second
Alcohol absorbs to obtain concentration absorbing liquid；It is concentrated in absorbing liquid onto the pillar equipped with macroporous absorbent resin, applied sample amount is weight resin
The concentration absorbing liquid of equivalent, loading flow control is in 2 bed volumes per hour；With the ethyl alcohol analytic tree of mass fraction 65-75%
The ginsenoside effective component of rouge absorption, elution liquid measure are 6-7 times of weight resin, and elution flow rate is controlled in 1-1.2 per hour
A bed volume collects to obtain ginsenoside eluent；Ginsenoside eluent is put into bleacher, it is corresponding that eluent is added
The magnesia of equivalent gen-seng haulms raw material weight 10% is stirred reflux decoloration 1-1.5h, then carries out plate-frame filtering, washing,
It collects to merge and obtains magnesia decolorization filtering liquid and cleaning solution；It is dense that magnesia decolorization filtering liquid and cleaning solution are subjected to vacuum decompression
Contracting, thickening temperature≤80 DEG C are concentrated vacuum degree≤- 0.08MPa, are concentrated into condensed cream specific gravity 1.1-1.15, rear to be spray-dried, i.e.,
Obtain ginsenoside powder；
C, the preparation of curcumin
It will be granulated under conditions of logical steam after curcuma grinds, granularity is 30-60 mesh；Gained after being granulated
Grain is extracted with leaching liquor, and leaching liquor is ethyl alcohol；It in temperature is 100-110 DEG C by extracting solution, mill pressure is handled under 5-7 atmospheric pressure,
Fineness of grind is 90-150 mesh to get curcumin powder；
D, the preparation of pachymaran
Poria cocos is crushed and screened into 20 mesh coarse powder, 5-10 times of distilled water is then added, ultrasound adverse current heating is boiled 1.5-2h, mentioned
It takes 4 times；Extracting solution is subjected to separation, impurity removal, merging filtrate by centrifuge；Filtrate is with microfiltration membranes PP cotton coarse filtration, coarse filtration temperature
25-35 DEG C, pressure 0.1-0.5Mpa；It is the polysulfone hollow fibre of 10000 dalton by coarse filtration filtrate nominal molecular cut off
Formula ultrafiltration membrane (UF) further refined filtration, 25-35 DEG C of refined filtration temperature, pressure 0.05-0.1Mpa；By refined filtration filtrate temperature be 35-
45 DEG C, mill pressure processing under 8-9 atmospheric pressure, fineness of grind is 100-130 mesh, then is done by way of vacuum freeze drying
It is dry to get arrive pachymaran powder；
E, by above-mentioned Chinese chestnut Gly-His-Lys, ginsenoside powder, curcumin powder and pachymaran powder, then it is subject to Schisandra chinens P.E and chrysanthemum
Extract is mixed to arrive the solid beverage of Chinese chestnut peptide.
Embodiment 2:
A kind of solid beverage and preparation method thereof of Chinese chestnut peptide provided in this embodiment, preparation method are consistent with embodiment 1.
But a kind of solid beverage of Chinese chestnut peptide in the present embodiment, the weight percent group ratio of raw material are as follows: Chinese chestnut peptide 90%,
Ginsenoside 5%, curcumin 2%, pachymaran 1%, Schisandra chinens P.E 1% and chrysanthemum extract 1%.
Embodiment 3:
A kind of solid beverage and preparation method thereof of Chinese chestnut peptide provided in this embodiment, preparation method are consistent with embodiment 1.
But a kind of solid beverage of Chinese chestnut peptide in the present embodiment, the weight percent group ratio of raw material are as follows: Chinese chestnut peptide 85%,
Ginsenoside 7%, curcumin 4%, pachymaran 2%, Schisandra chinens P.E 1.5% and chrysanthemum extract 0.5%.
The sample of above-described embodiment 1 to embodiment 3 is used for tests on white mice.Prepare test white mouse 40, be divided into A, B, C and
D group, every group 10.Wherein, A group white mouse goes back fed continuous embodiment 1 within the six months of test duration in addition to diet
In Chinese chestnut peptide solid beverage；B group white mouse goes back fed continuous implementation within the six months of test duration in addition to diet
The solid beverage of Chinese chestnut peptide in example 2；C group white mouse goes back fed continuous within the six months of test duration in addition to diet
The solid beverage of Chinese chestnut peptide in embodiment 3；And D group white mouse only diet within the six months of test duration.Test knot
Fruit shows the D group that compares, the vital signs such as pulse, breathing, blood pressure, body temperature, the blood oxygen saturation (SpO2) of A-C group white mouse it is steady
Rate is determined obviously higher than D group.
The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, for the skill of this field
For art personnel, the invention may be variously modified and varied.All within the spirits and principles of the present invention, made any to repair
Change, equivalent replacement, improvement etc., should all be included in the protection scope of the present invention.
Claims (3)
1. a kind of solid beverage of Chinese chestnut peptide, it is characterized in that the weight percent group ratio of raw material are as follows: Chinese chestnut peptide 80-90%, ginsenoside
5-8%, curcumin 2-5%, pachymaran 1-3%, Schisandra chinens P.E 1-3% and chrysanthemum extract 0.5-1.5%.
2. a kind of preparation method of the solid beverage of Chinese chestnut peptide, it is characterized in that including the following steps:
A, the preparation of Chinese chestnut peptide
Chinese chestnut Seed after cleaning is placed in the VC solution or citric acid solution of color protection and impregnates 3-6h, then grinds slurrying；It will
Slurries are 130-135 DEG C in temperature, and mill pressure processing under 6-8 atmospheric pressure, fineness of grind is 120-160 mesh, then passes through 120-150
DEG C ultra high temperature short time sterilization processing, after be cooled to 30-55 DEG C；It is added in slurries after sterilization and accounts for weight of material 1.0-1.5%
Carbohydrase in slurries chestnut starch saccharification handle, time 3-4.5h, temperature be 30-40 DEG C；By the slurries after saccharification
Be heated to 80-100 DEG C of progress destroy the enzyme treatment, after be cooled to 25-40 DEG C, then be then added with hydrochloric acid adjustment pH value to 3.5-5.5
It accounts for the acid protease of weight of material 0.5-2.5% and the lipase of 0.1-0.15% and carries out that 5-10min is sufficiently stirred, it is rear to carry out
Constant temperature stands 12-15h and carries out biochemical degradation condensation；The supernatant obtained after biochemical degradation is condensed extracts, then passes through 90-
Destroy the enzyme treatment under the conditions of 105 DEG C, then refined filtration obtains Chinese chestnut peptide stoste, and Chinese chestnut Gly-His-Lys are made after concentration；
B, the preparation of ginsenoside
Ginseng is cleaned into slice, the distilled water for accounting for weight of material 50-55% is added and is stirred evenly, mixing time 1-3h；By even liquid
It is 60-75 DEG C in temperature, mill pressure processing under 3-5 atmospheric pressure, fineness of grind is 100-150 mesh；Add fermenting microbe into even liquid
Fermentation；Fermentation liquid is imported in extraction kettle, supercritical CO is used2As extractant, beeswax is as entrainer, in extraction temperature
Under 20-25 DEG C, Fluid pressure 25-35MPa, flow velocity 0.1-0.4ml/min, extraction 1-3h obtains extract, extract second
Alcohol absorbs to obtain concentration absorbing liquid；It is concentrated in absorbing liquid onto the pillar equipped with macroporous absorbent resin, applied sample amount is weight resin
The concentration absorbing liquid of equivalent, loading flow control is in 2 bed volumes per hour；With the ethyl alcohol analytic tree of mass fraction 65-75%
The ginsenoside effective component of rouge absorption, elution liquid measure are 6-7 times of weight resin, and elution flow rate is controlled in 1-1.2 per hour
A bed volume collects to obtain ginsenoside eluent；Ginsenoside eluent is put into bleacher, it is corresponding that eluent is added
The magnesia of equivalent gen-seng haulms raw material weight 10% is stirred reflux decoloration 1-1.5h, then carries out plate-frame filtering, washing,
It collects to merge and obtains magnesia decolorization filtering liquid and cleaning solution；It is dense that magnesia decolorization filtering liquid and cleaning solution are subjected to vacuum decompression
Contracting, thickening temperature≤80 DEG C are concentrated vacuum degree≤- 0.08MPa, are concentrated into condensed cream specific gravity 1.1-1.15, rear to be spray-dried, i.e.,
Obtain ginsenoside powder；
C, the preparation of curcumin
It will be granulated under conditions of logical steam after curcuma grinds, granularity is 30-60 mesh；Gained after being granulated
Grain is extracted with leaching liquor, and leaching liquor is ethyl alcohol；It in temperature is 100-110 DEG C by extracting solution, mill pressure is handled under 5-7 atmospheric pressure,
Fineness of grind is 90-150 mesh to get curcumin powder；
D, the preparation of pachymaran
Poria cocos is crushed and screened into 20 mesh coarse powder, 5-10 times of distilled water is then added, ultrasound adverse current heating is boiled 1.5-2h, mentioned
It takes 4 times；Extracting solution is subjected to separation, impurity removal, merging filtrate by centrifuge；Filtrate is with microfiltration membranes PP cotton coarse filtration, coarse filtration temperature
25-35 DEG C, pressure 0.1-0.5Mpa；It is the polysulfone hollow fibre of 10000 dalton by coarse filtration filtrate nominal molecular cut off
Formula ultrafiltration membrane (UF) further refined filtration, 25-35 DEG C of refined filtration temperature, pressure 0.05-0.1Mpa；By refined filtration filtrate temperature be 35-
45 DEG C, mill pressure processing under 8-9 atmospheric pressure, fineness of grind is 100-130 mesh, then is done by way of vacuum freeze drying
It is dry to get arrive pachymaran powder；
E, by above-mentioned Chinese chestnut Gly-His-Lys, ginsenoside powder, curcumin powder and pachymaran powder, then it is subject to Schisandra chinens P.E and chrysanthemum
Extract is mixed to arrive the solid beverage of Chinese chestnut peptide；The wherein weight percent group ratio of raw material are as follows: Chinese chestnut peptide 80-90%,
Ginsenoside 5-8%, curcumin 2-5%, pachymaran 1-3%, Schisandra chinens P.E 1-3% and chrysanthemum extract 0.5-1.5%.
3. the preparation method of the solid beverage of a kind of Chinese chestnut peptide according to claim 2, it is characterized in that institute in above-mentioned steps c
Stating curcuma includes one or more of turmeric, curcuma zedoary and Radix Curcumae.
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| CN110679817A (en) * | 2019-10-29 | 2020-01-14 | 徐州三源医药科技集团有限公司 | A solid beverage for improving dyspepsia and its preparation method |
| CN111543573A (en) * | 2020-06-28 | 2020-08-18 | 广东亨盛维嘉食品工业有限公司 | Peptide solid beverage for beauty treatment |
| CN111567714A (en) * | 2020-06-28 | 2020-08-25 | 广东亨盛维嘉食品工业有限公司 | Solid beverage capable of effectively helping sleep |
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