CN105831318A - Polypeptide tea for blood glucose reduction and manufacturing method of polypeptide tea - Google Patents
Polypeptide tea for blood glucose reduction and manufacturing method of polypeptide tea Download PDFInfo
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- CN105831318A CN105831318A CN201610232048.4A CN201610232048A CN105831318A CN 105831318 A CN105831318 A CN 105831318A CN 201610232048 A CN201610232048 A CN 201610232048A CN 105831318 A CN105831318 A CN 105831318A
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- China
- Prior art keywords
- extract
- tea
- rhizoma polygonati
- radix puerariae
- polygonati odorati
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/06—Treating tea before extraction; Preparations produced thereby
- A23F3/14—Tea preparations, e.g. using additives
Abstract
The invention provides polypeptide tea for blood glucose reduction and a manufacturing method of the polypeptide tea. The tea comprises a bitter gourd extract, a rhizoma polygonati odorati extract, and a radix puerariae extract, and is abundant in effective components including vitamins, trace elements, amino acids, tea polysaccharide, rhizoma polygonati odorati polysaccharide, steroidal glycoside, daidzein, daidzin, puerarin, and puerarin-7-xyloside, and has the efficacy of clearing heat and engendering fluid, reducing blood glucose and wiping off grease, and resolving stasis and free the collateral vessels. The tea is suitable for patients who has abnormal glucose tolerance and suffers from slight diabetes, and has the efficacy of reducing fasting blood glucose. The polypeptide tea for blood glucose reduction has properties as medicines and takes like tea, and the formula of the tea is based on the traditional Chinese medicine curative theory of yin-yang balance and healthy qi reinforcement.
Description
Technical field
The invention belongs to polypeptide beverage field, particularly relate to peptide species blood-sugar reducing tea and a system thereof
Make method.
Background technology
Diabetes spp, in endocrinopathy, is due to internal hypoinsulinism, causes
Sugar, protein and water-electrolyte metabolism are disorderly and the disease that causes, it directly destroy the heart,
Brain, kidney, eye and nervous tissue's organ, be after tumor, cancer and cardiovascular disease
Relatively refractory the third-largest noninfectious more.
From natural plants find pure natural, safe and nontoxic, have no side effect prevent and treat diabetes,
The health food of auxiliary hyperglycemic is an economically viable effective way.
China is the native place of Folium Camelliae sinensis, Shi Chan tea big country, and tea resources is the abundantest, the most always
The Lao Ye of the old Camellia sinensis of tea system, is had because of not good enough the going out of use of taste always for a long time
Effect utilizes, and causes the wasting of resources.China's the most useful coarse tea among the people with Japan is controlled according to records
The tradition of diabetes, Recent study shows that its main composition is tea polysaccharide.Tea is many
The main rich content in the Lao Ye of old Camellia sinensis of sugar, and the age of tree is the highest, Folium Camelliae sinensis is the thickest always contains
Measure the highest.
Radix Puerariae system legume pueraria lobata, containing flavone compound, including Dai, big
Bean glycoside, puerarin, puerarin-7-xyloside, and several amino acids, can be as medicine
Application.Radix Puerariae is cool in nature, sweet in the mouth, pungent, records according to Compendium of Material Medica, have heat clearing away,
Pathogenic fire reducing, effect of toxin expelling, modern medicine study shows, the osajin chemical combination in Radix Puerariae
Thing puerarin has certain curative effect to hypertension, hyperlipidemia, hyperglycemia and cardiovascular and cerebrovascular disease.
In recent years, the development along with collagen extraction techniques and the merit to collagen protein polypeptide
The raising of energy character understanding, the research of collagen protein polypeptide becomes a new heat with application
Point, therefore researches and develops the beverage products rich in collagen protein polypeptide and has the most existing
Sincere justice, relevant patent also gets more and more, as (open in polypeptide milk beverage and preparation method thereof
Number CN101084767A), collagen protein milk drink and production method (publication number thereof
CN1943369A), it is all the beverage adding appropriate collagen protein in milk product.
Also having some is the product carrying out collagen protein and fruit and vegetable juice being combined, as containing compound ammonia
The watermelon water collagen beverage (publication number CN101491358A) of base acid, a kind of collagen
Protein beverage and preparation method thereof (publication number CN101912132A), collagen beverage
Formula (publication number CN101946961A) and a kind of collagen beverage preparation and
Preparation method (publication number CN102771869A).Although this type of beverage taste is complete, plant
Class is various, but its nutritional labeling is more single, and the various nutritional labelings of needed by human body are not
Can comprehensively be supplemented, and sugar content is higher, easily causes after patients with diabetes mellitus
The most serious carbohydrate metabolism is not normal.
Summary of the invention
In view of this, the present invention one peptide species blood-sugar reducing tea, it is intended to improve having of polypeptide teas
Effective substance composition.
The present invention is achieved in that
One peptide species blood-sugar reducing tea, extracts including Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract and Radix Puerariae
Thing；The mass percent of described Fructus Momordicae charantiae extract be 10～45%, the matter of Rhizoma Polygonati Odorati extract
Amount percentage ratio is 10～the mass percent of 45%, Radix Puerariae extract is 10～45%.
Alternatively, Rhizoma Polygonati, the Radix Astragali, Radix Scutellariae, Poria, Fructus Mume, old tea are also included；Its
In the mass percent of each raw material components be:
Rhizoma Polygonati 5～20%
The Radix Astragali 5～20%
Radix Scutellariae 5～20%
Poria 5～20%
Fructus Mume 5～20%
Old tea 5～20%.
Alternatively, the mass percent of each raw material components is:
Fructus Momordicae charantiae extract 10～30%
Rhizoma Polygonati Odorati extract 10～30%
Radix Puerariae extract 10～30%
Rhizoma Polygonati 5～20%
The Radix Astragali 5～20%
Radix Scutellariae 5～20%
Poria 5～20%
Fructus Mume 5～20%
Old tea 5～20%.
Alternatively, the mass percent of each raw material components is:
Fructus Momordicae charantiae extract 10～20%
Rhizoma Polygonati Odorati extract 10～20%
Radix Puerariae extract 10～20%
Rhizoma Polygonati 5～15%
The Radix Astragali 5～15%
Radix Scutellariae 5～15%
Poria 5～15%
Fructus Mume 5～15%
Old tea 5～15%.
Present invention also offers the manufacture method of a peptide species blood-sugar reducing tea, comprise the following steps:
(1) prepare Fructus Momordicae charantiae extract: after Fructus Momordicae charantiae raw material pulverizing, add 8～15 times of weight
Water, heating extraction, extract 2～3 times, extract 2～5 hours every time, filter, close
And filtrate；Filtrate is concentrated into the 0.1～0.5 of original volume, and concentrated supernatant joins anhydrous second
In alcohol, stirring, stand；Ethanol is recovered by filtration, collects precipitation, be dried under vacuum to constant weight,
Obtain Fructus Momordicae charantiae extract.
(2) prepare Rhizoma Polygonati Odorati extract: after Rhizoma Polygonati Odorati raw material pulverizing, add water, feed liquid quality
Ratio is 1:15～20, and supersound extraction 10～60 minutes are filtered, merging filtrate；Filtrate concentrates
To the 0.1～0.5 of original volume, concentrated supernatant joins in dehydrated alcohol, stirring, stands；
Ethanol is recovered by filtration, collects precipitation, be dried under vacuum to constant weight, obtain Rhizoma Polygonati Odorati extract.
(3) Radix Puerariae extract is prepared:, use superfine communication technique to pulverize dry Radix Puerariae
Obtaining powder of Radix Puerariae, soak, feed liquid mass ratio is 1:300～400, ultrasonic after immersion carries
Take 10～60 minutes, filter, merging filtrate；Filtrate is concentrated into the 0.1～0.5 of original volume,
Concentrated supernatant joins in dehydrated alcohol, stirring, stands；Ethanol is recovered by filtration, receives
Collection precipitation, is dried under vacuum to constant weight, obtains Radix Puerariae extract.
(4) Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract and Radix Puerariae extract it are mixed in proportion.
Alternatively, in step (1)～(3), described water is deionized water.
Alternatively, in step (1)～(3) during vacuum drying, baking temperature is 45 DEG C.
Alternatively, in step (1)～(3) during vacuum drying, dry vacuum is
0.0095MPa.
Alternatively, when in step (1)～(3), concentrated supernatant joins in dehydrated alcohol,
Control final ethanol mass percent concentration in mixed liquor and be maintained at 50～90%.
Present invention also offers a peptide species Hypoglyemic liquid medicine sheet, including Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati
Extract, Radix Puerariae extract, adjuvant；The mass percent of each raw material components is: Fructus Momordicae charantiae
Extract 10～30%, Rhizoma Polygonati Odorati extract 10～30%, Radix Puerariae extract 10～30%, its
Remaining is adjuvant.
The present invention compared with prior art, has the advantage that
(1) this product mainly including, Radix Puerariae extract, Rhizoma Polygonati Odorati extract and Fructus Momordicae charantiae extract
Thing, rich in vitamin, trace element, aminoacid, tea polysaccharide, fragrant solomonseal rhizome polyoses, steroid glycoside,
The effective ingredient such as Dai, daidzin, puerarin, puerarin-7-xyloside, have clear
Heat is promoted the production of body fluid, blood sugar lowering dispels fat, effect of disperse blood stasis and dredge collateral, it is adaptable to impaired glucose tolerance is with slight
Diabetics.
(2) experimentation proves that the present invention has the effect reducing fasting glucose.
(3) the tcm health preserving principle of " equilibrium between yin and yang, recovery consolidate " is followed on formula compatibility,
Get it filled the property of thing, the taste drunk tea.
Detailed description of the invention
The claim of the present invention is done further by the mode below in conjunction with specific embodiment
Describing in detail, but be not intended that any limitation of the invention, anyone weighs in the present invention
The amendment of the limited number of time made in profit claimed range, still in scope of the presently claimed invention
Within.
The invention provides a peptide species blood-sugar reducing tea, extract including Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati
Thing and Radix Puerariae extract；The mass percent of described Fructus Momordicae charantiae extract be 10～40%, beautiful
The mass percent of bamboo extract is 10～the mass percent of 40%, Radix Puerariae extract is
10～40%.
In aforementioned, Fructus Momordicae charantiae has another name called balsam pear, is Cucurbitaceae Cucurbitales Momordica plant, is one
Year life climbing herb.The sarcocarp of Fructus Momordicae charantiae is sliced, dry after can make medicinal, there is heat clearing away
Expelling summer-heat, improving eyesight removing toxic substances, diuresis removing heat from blood, solve labor clear away heart-fire, effect of QI invigorating tonifying YANG.Due to
Fructus Momordicae charantiae contains fat eliminating element, also has blood sugar lowering, antitumor, antiviral, antibacterial, promotion
Immunity etc. act on.
Fragrant solomonseal rhizome polyoses and steroid glycoside are one of principle active component in Rhizoma Polygonati Odorati, and fragrant solomonseal rhizome polyoses includes
Rhizoma Polygonati Odorati mucopolysaccharide and levan.There is nourishing YIN to relieve dryness, the function of promoting the production of body fluid to quench thirst.Modern times grind
Study carefully its physiologically active of proof notable, there is lowering blood pressure and blood fat, improve myocardial ischemia etc.
Effect.
Containing multiple osajin composition in Radix Puerariae, including Dai, daiazi, puerarin,
Puerarin-7-xyloside etc., wherein puerarin (puerarin) is the endemic element of this genus,
There is blood circulation promoting and blood stasis dispelling, improve the effect such as microcirculation, suppression aldose reductase activity.Radix Puerariae
Flavone has effect of lowering blood sugar, and the prevention and treatment to diabetic vascular complications has long-pending
The effect of pole.
It is verified by experiments, when Rhizoma Polygonati Odorati, Fructus Momordicae charantiae and Radix Puerariae are used in conjunction, is remarkably improved Radix Puerariae yellow
The blood sugar reducing function of ketone, the mechanism that its hypoglycemic activity strengthens is: Fructus Momordicae charantiae extract carries with Rhizoma Polygonati Odorati
Take thing jointly to act on down, improve Radix Puerariae flavone concentration in intestinal and to extend it stagnant
Stay the time so that it is preferably play suppression glucosidase activity, strengthen and reduce blood after the meal
The effect of sugar.
Further, Rhizoma Polygonati, the Radix Astragali, Radix Scutellariae, Poria, Fructus Mume, old tea are also included；
The mass percent of the most each raw material components is:
Rhizoma Polygonati 5～20%
The Radix Astragali 5～20%
Radix Scutellariae 5～20%
Poria 5～20%
Fructus Mume 5～20%
Old tea 5～20%.
In above-mentioned, Rhizoma Polygonati (Polygonatum sibiricum Red.) is the dry of liliaceous plant
Dry tuber, is China's Chinese medicine, has long blood sugar lowering applicating history.On the market
Many hypoglycemic pcm such as its main sugar-lowering components such as blood sugar lowering Tongmai Tablet, Rhizoma Polygonati Jiangtang capsule
It is Rhizoma Polygonati.Polygonatum polysaccharide is its main active, has blood sugar lowering, defying age work
With, strengthen the multiple efficacies such as immunologic function.
The Radix Astragali has dual regulation to blood glucose, and Radix Astragali saponin can be by promoting that islets of langerhans β is thin
Intracrine insulin plays hypoglycemic activity, and astragalus polysaccharides is protected to the cardiac muscle of diabetes
Effect.
The experimental results shows, diabetics interior free yl raises and raises with blood glucose
There is substantial connection.SOD is the important enzyme of scavenging activated oxygen, is removing in organism
The main defence line of oxygen-derived free radicals, has protection cell DNA, protein and the merit of cell membrane
Energy.Hyperglycemia can produce saccharification react with the Lysine binding in SOD active center, make
SOD activity decrease, weakens its removing to free radical.A large amount of free radicals produced are drawn
The oxidative damage risen, not only promotes diabetic cataract, microangiopathies and glycosuria
The generation of sick nephropathy etc., be also in early days arteriosclerosis and peripheral neuropathy be deformed into important
Factor, therefore removes the key that interior free yl is prevention diabetic complication.
Baicalin is one of Radix Scutellariae main component, makes the SOD activity in liver organization notable
Increasing, enhance the removing of free radical in liver, it is right because of free radical that baicalin can reduce
The damage of diabetics tissue.
Poria is a kind of aerobic saprophytic fungus, and slightly sweet flavor is put down, and enters the heart, lung, spleen channel.
There is eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, effect of mind tranquilizing and the heart calming.
Citric acid in Fructus Mume can promote the absorption of effective ingredient in this polypeptide blood-sugar reducing tea, and
Its mouthfeel can be regulated.
Recent study shows that old tea main composition is tea polysaccharide.Tea polysaccharide mainly exists
Rich content in the Lao Ye of old Camellia sinensis, and the age of tree is the highest, the thickest old content of Folium Camelliae sinensis is the highest,
There is preferable blood sugar lowering dispel effect of fat；Fructus Mume and Poria all can adjust old tea bitterness simultaneously
Mouthfeel.
The purpose of the present invention can be achieved through the following technical solutions: the polypeptide that the present invention provides
Blood-sugar reducing tea, the mass percent of each raw material components is:
Fructus Momordicae charantiae extract 10～30%
Rhizoma Polygonati Odorati extract 10～30%
Radix Puerariae extract 10～30%
Rhizoma Polygonati 5～20%
The Radix Astragali 5～20%
Radix Scutellariae 5～20%
Poria 5～20%
Fructus Mume 5～20%
Old tea 5～20%.
Further, the mass percent of each raw material components is:
Fructus Momordicae charantiae extract 10～20%
Rhizoma Polygonati Odorati extract 10～20%
Radix Puerariae extract 10～20%
Rhizoma Polygonati 5～15%
The Radix Astragali 5～15%
Radix Scutellariae 5～15%
Poria 5～15%
Fructus Mume 5～15%
Old tea 5～15%.
Present invention also offers the manufacture method of a peptide species blood-sugar reducing tea, comprise the following steps:
Step (1): prepare Fructus Momordicae charantiae extract: after Fructus Momordicae charantiae raw material pulverizing, adds 8～15
The water of times weight, heating extraction, extract 2～3 times, extract 2～5 hours, mistake every time
Filter, merging filtrate；Filtrate is concentrated into the 0.1～0.5 of original volume, and concentrated supernatant joins
In dehydrated alcohol, stirring, stand；Ethanol is recovered by filtration, collects precipitation, vacuum drying
To constant weight, obtain Fructus Momordicae charantiae extract.
In above-mentioned, utilize water alcohol method to extract the effective ingredient in Fructus Momordicae charantiae, add 8～15 times
The water of weight, heating extraction can shorten extraction time, improves the mouthfeel of Fructus Momordicae charantiae, needs reason
Solving, heating-up temperature is unsuitable too high, it is to avoid destroy the bioactive ingredients in Fructus Momordicae charantiae.
Preferably, the temperature of described heating extraction is 25～30 DEG C.
(2) prepare Rhizoma Polygonati Odorati extract: after Rhizoma Polygonati Odorati raw material pulverizing, add water, feed liquid quality
Ratio is 1:15～20, and supersound extraction 10～60 minutes are filtered, merging filtrate；Filtrate concentrates
To the 0.1～0.5 of original volume, concentrated supernatant joins in dehydrated alcohol, stirring, stands；
Ethanol is recovered by filtration, collects precipitation, be dried under vacuum to constant weight, obtain Rhizoma Polygonati Odorati extract.
In above-mentioned, water alcohol method combines ultrasonic extraction, shortens the cycle of extraction process,
The preferably effective ingredient in protection Rhizoma Polygonati Odorati raw material.
(3) Radix Puerariae extract is prepared:, use superfine communication technique to pulverize dry Radix Puerariae
Obtaining powder of Radix Puerariae, soak, feed liquid mass ratio is 1:300～400, ultrasonic after immersion carries
Take 10～60 minutes, filter, merging filtrate；Filtrate is concentrated into the 0.1～0.5 of original volume,
Concentrated supernatant joins in dehydrated alcohol, stirring, stands；Ethanol is recovered by filtration, receives
Collection precipitation, is dried under vacuum to constant weight, obtains Radix Puerariae extract.
In above-mentioned, water alcohol method combines ultrasonic extraction and combines, and shortens the week of extraction process
Phase, decrease the loss of active substance composition in Radix Puerariae, preferably save the battalion of Radix Puerariae
Support and be worth.
(4) Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract and Radix Puerariae extract it are mixed in proportion.
In above-mentioned, step (1)～(3) use different extraction works for different raw materials
Skill, has stronger specific aim, reduces the loss of each group of material effective component.
Further, in step (1)～(3), described water is deionized water.
In above-mentioned, deionized water, the holding time is better than distilled water, is difficult to cause antibacterial
Breeding, the holding time is longer.
Further, in step (1)～(3) during vacuum drying, baking temperature is 45 DEG C.
In above-mentioned, baking temperature is unsuitable too high, it is to avoid destroy the biology of each effective constituents
Activity.
Further, in step (1)～(3) during vacuum drying, dry vacuum is
0.0095MPa.
In above-mentioned, when dry vacuum is 0.0095MPa, vacuum to be less than saturated steaming
Vapour pressure, dry effect is more preferable.
Further, in step (1)～(3), concentrated supernatant joins in dehydrated alcohol
Time, control final ethanol mass percent concentration in mixed liquor and be maintained at 50～90%.
In above-mentioned, ethanol mass percent concentration final in mixed liquor is unsuitable too high, keeps away
Exempt to destroy the biological activity of each effective constituents.Preferably, in described mixed liquor finally
Ethanol mass percent be 80%.
Present invention also offers a peptide species Hypoglyemic liquid medicine sheet, including Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati
Extract, Radix Puerariae extract, adjuvant；The mass percent of each raw material components is: Fructus Momordicae charantiae
Extract 10～30%, Rhizoma Polygonati Odorati extract 10～30%, Radix Puerariae extract 10～30%, its
Remaining is adjuvant.
Above-mentioned, the adjuvant of polypeptide blood sugar lowering decoction pieces includes acid source and the disintegrate soda acid of alkali source composition
Right, this acid source and alkali source can react generation carbon dioxide in water.It is understood that
Described polypeptide blood sugar lowering decoction pieces can also make polypeptide blood sugar lowering effervescent tablet, it is also possible to makes many
Peptide Jiangtang capsule.
It is to be appreciated that polypeptide blood-sugar reducing tea can also drink together with other beverages or make
For drinking for compound beverage, as made polypeptide blood sugar lowering green tea with green tea, technological process is as follows:
Dry polypeptide blood-sugar reducing tea solids powder is dissolved in water, control water temperature 30～50 DEG C, take
Green tea, mixing is pulled Folium Camelliae sinensis out, is vacuum dried and obtains polypeptide blood-sugar reducing tea green tea after soaking.
In above-mentioned, green tea extract has suppression to alpha-glucosidase and α-amylase
Effect.
In diabetes hypoglycemic medicines family alpha-glucosidase inhibitor be one group by prolonging
The digestion of slow sugar and absorption reduce the oral antidiabetic drug of post-prandial glycemia purpose, and it is made
It is that the final step suppression disaccharidase digested at sugar is degraded to monosaccharide by feature.α-amylase presses down
Preparation also can slow down food starch digestion in intestinal, the liter of suppression level of postprandial blood sugar
High.
For the ease of understanding the present invention, further illustrate the present invention below in conjunction with embodiment
Technical scheme.Applicant states, the present invention illustrates the present invention by above-described embodiment
Detailed process equipment and technological process, but the invention is not limited in above-mentioned detailed process
Equipment and technological process, i.e. do not mean that the present invention has to rely on above-mentioned detailed process equipment
Could implement with technological process.Person of ordinary skill in the field it will be clearly understood that to this
Any improvement of invention, the equivalence of raw material each to product of the present invention is replaced and auxiliary element
Interpolation, concrete way choice etc., all fall within protection scope of the present invention and open scope
Within.
Embodiment 1
The polypeptide blood-sugar reducing tea that the present invention provides, the mass percent of each raw material components is:
Fructus Momordicae charantiae extract 45%
Rhizoma Polygonati Odorati extract 45%
Radix Puerariae extract 10%
Embodiment 2
The polypeptide blood-sugar reducing tea that the present invention provides, the mass percent of each raw material components is:
Fructus Momordicae charantiae extract 10%
Rhizoma Polygonati Odorati extract 45%
Radix Puerariae extract 45%
Embodiment 3
The polypeptide blood-sugar reducing tea that the present invention provides, the mass percent of each raw material components is:
Fructus Momordicae charantiae extract 45%
Rhizoma Polygonati Odorati extract 10%
Radix Puerariae extract 45%
Embodiment 4
The polypeptide blood-sugar reducing tea that the present invention provides, the mass percent of each raw material components is:
Fructus Momordicae charantiae extract 30%
Rhizoma Polygonati Odorati extract 10%
Radix Puerariae extract 10%
Rhizoma Polygonati 5%
The Radix Astragali 10%
Radix Scutellariae 5%
Poria 5%
Fructus Mume 5%
Old tea 20%.
Embodiment 5
The polypeptide blood-sugar reducing tea that the present invention provides, the mass percent of each raw material components is:
Fructus Momordicae charantiae extract 10%
Rhizoma Polygonati Odorati extract 10%
Radix Puerariae extract 30%
Rhizoma Polygonati 10%
The Radix Astragali 20%
Radix Scutellariae 5%
Poria 5%
Fructus Mume 5%
Old tea 5%.
Embodiment 6
The polypeptide blood-sugar reducing tea that the present invention provides, the mass percent of each raw material components is:
Fructus Momordicae charantiae extract 20%
Rhizoma Polygonati Odorati extract 20%
Radix Puerariae extract 10%
Rhizoma Polygonati 5%
The Radix Astragali 20%
Radix Scutellariae 5%
Poria 10%
Fructus Mume 5%
Old tea 5%.
Embodiment 7
The polypeptide blood-sugar reducing tea that the present invention provides, the mass percent of each raw material components is:
Fructus Momordicae charantiae extract 15%
Rhizoma Polygonati Odorati extract 15%
Radix Puerariae extract 15%
Rhizoma Polygonati 5%
The Radix Astragali 15%
Radix Scutellariae 20%
Poria 5%
Fructus Mume 5%
Old tea 5%.
Embodiment 8
The polypeptide blood-sugar reducing tea that the present invention provides, the mass percent of each raw material components is:
Fructus Momordicae charantiae extract 10%
Rhizoma Polygonati Odorati extract 10%
Radix Puerariae extract 10%
Rhizoma Polygonati 10%
The Radix Astragali 10%
Radix Scutellariae 10%
Poria 20%
Fructus Mume 10%
Old tea 10%.
Embodiment 9
The polypeptide blood-sugar reducing tea that the present invention provides, the mass percent of each raw material components is:
Fructus Momordicae charantiae extract 10%
Rhizoma Polygonati Odorati extract 10%
Radix Puerariae extract 10%
Rhizoma Polygonati 10%
The Radix Astragali 10%
Radix Scutellariae 10%
Poria 10%
Fructus Mume 20%
Old tea 10%.
Embodiment 10
The polypeptide blood-sugar reducing tea that the present invention provides, the mass percent of each raw material components is:
Fructus Momordicae charantiae extract 10%
Rhizoma Polygonati Odorati extract 10%
Radix Puerariae extract 10%
Rhizoma Polygonati 10%
The Radix Astragali 10%
Radix Scutellariae 10%
Poria 10%
Fructus Mume 10%
Old tea 20%.
Embodiment 11
The polypeptide blood-sugar reducing tea that the present invention provides, the mass percent of each raw material components is:
Fructus Momordicae charantiae extract 16%
Rhizoma Polygonati Odorati extract 15%
Radix Puerariae extract 15%
Rhizoma Polygonati 10%
The Radix Astragali 10%
Radix Scutellariae 10%
Poria 8%
Fructus Mume 8%
Old tea 8%.
Embodiment 12
The polypeptide blood-sugar reducing tea that the present invention provides, the mass percent of each raw material components is:
Fructus Momordicae charantiae extract 15%
Rhizoma Polygonati Odorati extract 15%
Radix Puerariae extract 16%
Rhizoma Polygonati 10%
The Radix Astragali 10%
Radix Scutellariae 10%
Poria 8%
Fructus Mume 8%
Old tea 8%.
Matched group 1
Blood-sugar reducing tea common in market, is mainly composed of Radix Puerariae extract and Folium Nelumbinis extract.
Matched group 2
Blood-sugar reducing tea common in market, is mainly composed of Radix Puerariae extract, Fructus Momordicae, jasmine
Jasmine, flower of Radix Notoginseng and Folium Psidii Guajavae.
Specific experiment process: recruiting 35 example Western medicine diagnoses is the patient of type ii diabetes, year
Age between 35～68 years old, give the present invention provide polypeptide blood-sugar reducing tea, every day 2 times,
1g every time, with 1 month as observation period, the fasting glucose observing type ii diabetes patient becomes
Change situation.
MAIN OUTCOME MEASURES: fasting glucose (FPG), fasting glucose (FPG) observes knot
Fruit is shown in Table 1.
Table 1: the comparison before and after fasting glucose (FPG) treatment
| Embodiment | Before treatment | After treatment |
| Embodiment 1 | 6.31±0.08 | 3.96±0.13 |
| Embodiment 2 | 6.31±0.08 | 3.95±0.20 |
| Embodiment 3 | 6.31±0.08 | 4.02±0.15 |
| Embodiment 4 | 6.31±0.08 | 3.98±0.11 |
| Embodiment 5 | 6.31±0.08 | 3.88±0.20 |
| Embodiment 6 | 6.31±0.08 | 3.97±0.03 |
| Embodiment 7 | 6.31±0.08 | 3.90±0.15 |
| Embodiment 8 | 6.31±0.08 | 4.01±0.21 |
| Embodiment 9 | 6.31±0.08 | 3.92±0.14 |
| Embodiment 10 | 6.31±0.08 | 3.99±0.12 |
| Embodiment 11 | 6.31±0.08 | 3.92±0.20 |
| Embodiment 12 | 6.31±0.08 | 3.94±0.04 |
| Matched group 1 | 6.31±0.08 | 4.59±0.10 |
| Matched group 2 | 6.31±0.08 | 4.66±0.22 |
From table 1, significant difference (p before and after fasting glucose (FPG) after treating 1 month
＜ 0.05), illustrate that polypeptide blood-sugar reducing tea of the present invention has and preferably reduce fasting glucose (FPG)
Effect.
Claims (10)
1. a peptide species blood-sugar reducing tea, it is characterised in that: include Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract and Radix Puerariae extract；The mass percent of described Fructus Momordicae charantiae extract is 10～the mass percent of 45%, Rhizoma Polygonati Odorati extract is 10～the mass percent of 45%, Radix Puerariae extract is 10～45%.
2. polypeptide blood-sugar reducing tea as claimed in claim 1, it is characterised in that: also include Rhizoma Polygonati, the Radix Astragali, Radix Scutellariae, Poria, Fructus Mume, old tea；The mass percent of the most each raw material components is:
Rhizoma Polygonati 5～20%
The Radix Astragali 5～20%
Radix Scutellariae 5～20%
Poria 5～20%
Fructus Mume 5～20%
Old tea 5～20%.
3. polypeptide blood-sugar reducing tea as claimed in claim 2, it is characterised in that: the mass percent of each raw material components is:
Fructus Momordicae charantiae extract 10～30%
Rhizoma Polygonati Odorati extract 10～30%
Radix Puerariae extract 10～30%
Rhizoma Polygonati 5～20%
The Radix Astragali 5～20%
Radix Scutellariae 5～20%
Poria 5～20%
Fructus Mume 5～20%
Old tea 5～20%.
4. polypeptide blood-sugar reducing tea as claimed in claim 2, it is characterised in that: the mass percent of each raw material components is:
Fructus Momordicae charantiae extract 10～20%
Rhizoma Polygonati Odorati extract 10～20%
Radix Puerariae extract 10～20%
Rhizoma Polygonati 5～15%
The Radix Astragali 5～15%
Radix Scutellariae 5～15%
Poria 5～15%
Fructus Mume 5～15%
Old tea 5～15%.
5. the manufacture method of a peptide species blood-sugar reducing tea, it is characterised in that comprise the following steps:
(1) prepare Fructus Momordicae charantiae extract: after Fructus Momordicae charantiae raw material pulverizing, add the water of 8～15 times of weight, heating extraction, extract 2～3 times, extract 2～5 hours every time, filter, merging filtrate；Filtrate is concentrated into the 0.1～0.5 of original volume, and concentrated supernatant joins in dehydrated alcohol, stirring, stands；Ethanol is recovered by filtration, collects precipitation, be dried under vacuum to constant weight, obtain Fructus Momordicae charantiae extract；
(2) preparing Rhizoma Polygonati Odorati extract: after Rhizoma Polygonati Odorati raw material pulverizing, add water, feed liquid mass ratio is 1:15～20, supersound extraction 10～60 minutes, filters, merging filtrate；Filtrate is concentrated into the 0.1～0.5 of original volume, and concentrated supernatant joins in dehydrated alcohol, stirring, stands；Ethanol is recovered by filtration, collects precipitation, be dried under vacuum to constant weight, obtain Rhizoma Polygonati Odorati extract；
(3) Radix Puerariae extract is prepared:, use superfine communication technique to pulverize dry Radix Puerariae and obtain powder of Radix Puerariae, soak, feed liquid mass ratio is 1:300～400, supersound extraction 10～60 minutes after immersion, filters, merging filtrate；Filtrate is concentrated into the 0.1～0.5 of original volume, and concentrated supernatant joins in dehydrated alcohol, stirring, stands；Ethanol is recovered by filtration, collects precipitation, be dried under vacuum to constant weight, obtain Radix Puerariae extract；
(4) after being mixed in proportion Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract and Radix Puerariae extract, it is dried, sieves, prepare polypeptide blood-sugar reducing tea.
6. the manufacture method of polypeptide blood-sugar reducing tea as claimed in claim 5: it is characterized in that, in step (1)～(3), described water is deionized water.
7. the manufacture method of polypeptide blood-sugar reducing tea as claimed in claim 5: it is characterized in that, in step (1)～(3) during vacuum drying, baking temperature is 45 DEG C.
8. the manufacture method of polypeptide blood-sugar reducing tea as claimed in claim 5: it is characterized in that, in step (1)～(3) during vacuum drying, dry vacuum is 0.0095MPa.
9. the manufacture method of polypeptide blood-sugar reducing tea as claimed in claim 5: it is characterized in that, when concentrated supernatant joins in dehydrated alcohol in step (1)～(3), control final ethanol mass percent concentration in mixed liquor and be maintained at 50～90%.
10. a peptide species Hypoglyemic liquid medicine sheet, it is characterised in that: include Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract, Radix Puerariae extract, adjuvant；The mass percent of each raw material components is: Fructus Momordicae charantiae extract 10～30%, Rhizoma Polygonati Odorati extract 10～30%, Radix Puerariae extract 10～30%, remaining is adjuvant.
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| CN106236855A (en) * | 2016-08-25 | 2016-12-21 | 成都润馨堂药业有限公司 | A kind of compositions of assisting in reducing blood sugar |
| CN106261428A (en) * | 2016-10-25 | 2017-01-04 | 孙光周 | Clearing away summer-heat drink and compound method thereof |
| CN109275752A (en) * | 2017-07-20 | 2019-01-29 | 张家界茶坤缘生物科技开发有限公司 | A kind of diabetes recuperating tea and preparation method thereof |
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