CN1887306A - Active bitter gourd soft capsule and its prepn - Google Patents
Active bitter gourd soft capsule and its prepn Download PDFInfo
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- CN1887306A CN1887306A CN 200510079756 CN200510079756A CN1887306A CN 1887306 A CN1887306 A CN 1887306A CN 200510079756 CN200510079756 CN 200510079756 CN 200510079756 A CN200510079756 A CN 200510079756A CN 1887306 A CN1887306 A CN 1887306A
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- bitter gourd
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Abstract
The present invention is active bitter gourd soft capsule and its preparation process. The active bitter gourd soft capsule has inclusion comprising superfine active bitter gourd powder, prepared with fresh bitter gourd and through pulping, vacuum low temperature drying and low temperature airflow grinding, special vegetable oil, suspending agent and antioxidant in certain weight proportion; and capsule shell made with the material comprising gelatin, water, glycerin and polyethylene glycol in certain weight proportion. Compared with available technology, the present invention has the advantages of well maintenance of the active matters in bitter gourd, high bioavailability, long preservation period, and raised health function.
Description
Technical field
What the present invention relates to is a kind of medicine or health food and preparation method thereof, and referring in particular to fresh Fructus Momordicae charantiae is active bitter gourd soft capsule of raw material and preparation method thereof.
Background technology
Fructus Momordicae charantiae has another name called balsam pear, brocade (gold) Fructus Litchi, leprosy Fructus Vitis viniferae, Calyx Seu Fructus Physalis, balsam pear, gentleman's dish etc., belongs to annual trailing plant, because its nutritive value and medical value are higher, generally as vegetable growing.The Fructus Momordicae charantiae main component has Charantin, Charantin (being high energy fat eliminating element), insulin-like activity substance (being bitter gourd polypeptide class material) and multivitamin, aminoacid.In addition, according to the trophic analysis data, Fructus Momordicae charantiae nutritious, ascorbic acid content is outstanding in melon, is 14 times of Fructus Cucumidis sativi, 5 times of Fructus Benincasae, 7 times of Fructus Lycopersici esculenti.Contain 0.08 milligram of vitamin A, vitaminB10 .07 milligram, 0.04 milligram of vitamin B2 in per 100 gram fresh fruit meat, 84 milligrams of vitamin Cs, 0.3 milligram of nicotinic acid, 0.9 milligram in protein, 0.2 milligram in fat, carbohydrate 3.2 grams, 0.6 milligram of inorganic salt, calcareous 18 milligrams, 29 milligrams in phosphorus, 0.6 milligram of ferrum, crude fibre 1.1 grams, heat 75.3 kilojoules.
High energy fat eliminating element, i.e. Charantin (RPA), the magistery of this being described as " fatty killer " can make the fat of picked-up and polysaccharide reduce about 40%-60%.Pharmacological research confirms, high energy fat eliminating element does not enter blood of human body, only act on the significant points of absorption of human body fat---small intestinal, by changing the enterocyte mesh, stop the absorption of high heat macromolecular substances such as fat, polysaccharide, thereby the absorption of micromolecule nutrition does not participate in body metabolism again, so without any side effects in the acceleration bodies.
Bitter gourd polypeptide class material has the effect of tangible blood sugar lowering, and zoopery confirms that the para-insulin material not only can make the blood glucose of severe diabetes mellitus animal descend, and makes its recover normal, no matter and injection, oral curative effect all identical; Bitter gourd polypeptide class material has fast gliquidone, regulates islet function, repairs the beta cell, increases the sensitivity of insulin, and prevention improves complication, blood lipid regulation, the effect that improves immunity.
Summary of the invention
The object of the present invention is to provide and a kind ofly utilize fresh Fructus Momordicae charantiae to be active bitter gourd soft capsule of raw material and preparation method thereof.The technical solution used in the present invention is:
Fresh Fructus Momordicae charantiae that at first will newly gather, moderate maturity (blooming back 12-15 days) soaks with clear water removes pesticide residues.To clean fresh Fructus Momordicae charantiae later (full melon connects flesh) with disintegrating machine and break into coarse particles, reuse colloid mill or other slurry milling apparatus further grind coarse particles, obtain Fructus Momordicae charantiae screened stock material.Fructus Momordicae charantiae screened stock material is got 80-150 purpose Fructus Momordicae charantiae fine powder (moisture content is controlled in 5%) through vacuum dehydrating at lower temperature, with the Fructus Momordicae charantiae fine powder with the low temperature supersonic jet mill carry out again micronizing collect 600-2500 purpose Fructus Momordicae charantiae superfine powder.This Fructus Momordicae charantiae superfine powder is owing to adopt wet grinding and the pulverizing of low temperature supersonic airstream, and processing temperature is extremely low, and the biological activity of active substance has obtained preserving to greatest extent in the Fructus Momordicae charantiae.Because slurry is to adopt vacuum dehydrating at lower temperature, thereby has guaranteed that to greatest extent wherein Charantin, bitter gourd polypeptide material, various vitamin, aminoacid isoreactivity material are not decomposed in drying.
Above gained active bitter gourd superfine powder is added a certain proportion of special vegetable oil and adjuvant, be pressed into the soft capsule of 500-1000mg by known soft capsule production equipment and technology.
The present invention is implemented by following scheme.
A kind of active bitter gourd soft capsule of the present invention comprises the soft capsule content of 60-80% and the soft capsule material of 40-20%, and it is made of following component and weight proportion:
By weight percentage
The capsule content is made up of 1 part of active bitter gourd superfine powder, special vegetable oil 0.5-10 part, suspending agent 0-0.5 part, antioxidant 0-0.55 part;
The capsule material is made up of 100 parts in gelatin, water 80-120 part, glycerol 10-60 part, Polyethylene Glycol 0-10 part.
The weight proportion of each component can be preferably:
By weight percentage
The capsule content is made up of 1 part of active bitter gourd superfine powder, special vegetable oil 1.5-6 part, suspending agent 0.02-0.3 part, antioxidant 0.01-0.35 part;
The capsule material is made up of 100 parts in gelatin, water 85-110 part, glycerol 35-55 part, Polyethylene Glycol 0.025-5 part.
Weight proportion the best of each component is:
By weight percentage
The capsule content is made up of 1 part of active bitter gourd superfine powder, special vegetable oil 2-4 part, suspending agent 0.025-0.2 part, antioxidant 0.03-0.25 part;
The capsule material is made up of 100 parts in gelatin, water 90-100 part, glycerol 40-50 part, Polyethylene Glycol 0.03-3 part.
The active bitter gourd soft capsule that mentioned component constitutes, described special vegetable oil is: the superfine product Camellia oil of the Extra Virgin of European Union's standard (Extra Virginolive Oil), GB one-level (Extra Virgin camellia Oil); Described suspending agent is: lecithin, Polyethylene Glycol, Cera Flava; Described antioxidant is: tea polyphenols, apple polyphenol, Herba Rosmarini Officinalis extract, phytic acid.
The soft capsule of producing is used
60The gamma-rays of Co carries out irradiation sterilization to be handled, and also can handle with high frequency sterilization or ultrasonic sterilization.
The present invention compared with prior art has the following advantages:
One, preserved more active substance, its bioavailability is got a greater increase;
Two, not perishable, carry taking convenience;
Three, sterilization is thorough, and major ingredient adjuvant and capsule material are all thoroughly sterilized;
Four, the special vegetable oil that adds of the present invention is European Union's standard Extra Virgin, GB one-level Camellia oil, has not only satisfied the demand of soft capsule pressing process, and Fructus Momordicae charantiae is further strengthened to the treatment and health function of body and expands.
The composition of olive oil
The monounsaturated fatty acid that contains 65.8-84.9% in a, the olive oil.Monounsaturated fatty acid is except supplying with a large amount of heat energy of human body, can also adjust the ratio of high and low density lipoprotein cholesterol in the human plasma, can increase the equilibrium concentration of the intravital high density lipoprotein HDL of people (good cholesterol) behind the edible olive oil, to guarantee the requirement of human body to cholesterol.But also can reduce the concentration of low density lipoprotein, LDL LDL (bad cholesterol) in the blood plasma, excessive to prevent cholesterol in human body.Monounsaturated fatty acid is a significant benefit to the health of the heart, brain, kidney, blood vessel.
Contain the polyunsaturated fatty acid about 3.5-22% in b, the olive oil, polyunsaturated fatty acid not only can be divided into omega-fatty acid (being mainly linolenic acid) and ω-6 fatty acid (being mainly linoleic acid). and these are necessary and human bodies of human body but also can not self synthetic fatty acid.So also be called essential fatty acid, according to world medical circle many decades studies have shown that the essential fatty acid of human body: when the ratio of the essential fatty acid content omega-fatty acid of human body and ω-6 fatty acid was 1: 4, various diseases was difficult to the invasion human body.And the ratio of contained essential fatty acid just in time is 1: 4 in the olive oil, and is similar with human milk.
Contain abundant trace element Squalene, Flavonoid substances and polyphenolic substance in c, the olive oil, can strengthen the immunity of human body, slow down aging.
D, it also contains the beta-carotene of 0.03 to 0.36 milligram of every hectogram, and the vitamin E of 1.2-43 milligram, and multiple fatsoluble vitamiies such as vitamin A, D, F, K are the necessary nutrient substance of human organ.Therefore current medical circle is known as olive oil and benefits one of healthy eating oil most.
The composition of Camellia oil is extremely similar to olive oil, ratio between composition also slightly is better than olive oil, also contains in the Oleum Camelliae " unexistent specific biological active substances of olive oil such as camellianin, tsubakisaponin; tea polyphenols etc.; wherein camellianin has cardiotonic, tsubakisaponin have the thrombus dissolving effect, can prevent the multiple cardiovascular and cerebrovascular disease that sclerosis of blood vessels causes; and tea polyphenols has cholesterol reducing; multiple effects such as chemoprophylaxis tumor, thereby, Oleum Camelliae be otherwise known as " long life oil ".
The specific embodiment:
Embodiment 1
By weight percentage
Get 1 part of active bitter gourd superfine powder, 2 parts in primary olive oil, 0.55 part of composition of Herba Rosmarini Officinalis extract capsule content, carry out homogenizing with high speed shear formula homogenizer and handle stand-by;
Get 100 parts in gelatin, 90 parts in water, 40 parts of glycerol, 0.03 part of composition of Polyethylene Glycol capsule material, set aside for use after the heating in water bath dissolving stirs;
The two is put into the soft capsule production equipment be pressed into soft capsule, the soft capsule after the dried packing is used
60The gamma-rays of Co is assisted according to sterilization treatment, or handles with high frequency sterilization, ultrasonic sterilization.
Embodiment 2
By weight percentage
Get 1 part of active bitter gourd superfine powder, 10 parts of Camellia oil, 0.5 part in lecithin, 0.2 part of composition of phytic acid capsule content, carry out homogenizing and handle stand-by;
Get 100 parts in gelatin, 95 parts in water, 42 parts of glycerol, 0.5 part of composition of Polyethylene Glycol capsule material, set aside for use after the heating in water bath dissolving stirs;
The two is put into the soft capsule production equipment be pressed into soft capsule, the capsule content accounts for 60% of weight in the soft capsule of making, and the capsule material accounts for 40% of weight.Soft capsule after the dried packing is used
60The gamma-rays of Co is assisted according to sterilization treatment, or handles with high frequency sterilization, ultrasonic sterilization.
Embodiment 3
By weight percentage
Get 1 part of active bitter gourd superfine powder, 0.5 part in olive oil, 0.03 part of Polyethylene Glycol, 0.04 part of composition of tea polyphenols capsule content, carry out homogenizing and handle stand-by;
Get 100 parts in gelatin, 100 parts in water, 30 parts of glycerol, 1 part of composition of Polyethylene Glycol capsule material, set aside for use after the heating in water bath dissolving stirs;
The two is put into the soft capsule production equipment be pressed into soft capsule, the capsule content accounts for 60% of weight in the soft capsule of making, and the capsule material accounts for 40% of weight.Soft capsule after the dried packing is used
60The gamma-rays of Co is assisted according to sterilization treatment, or handles with high frequency sterilization, ultrasonic sterilization.
Embodiment 4
By weight percentage
Get 1 part of active bitter gourd superfine powder, 4 parts of Oleum Camelliae, 0.05 part in Cera Flava, 0.001 part of composition of apple polyphenol capsule content, carry out homogenizing and handle stand-by;
Get 100 parts in gelatin, 100 parts in water, 30 parts of glycerol, 10 parts of compositions of Polyethylene Glycol capsule material, set aside for use after the heating in water bath dissolving stirs;
The two is put into the soft capsule production equipment be pressed into soft capsule, the capsule content accounts for 60% of weight in the soft capsule of making, and the capsule material accounts for 40% of weight.Soft capsule after the dried packing is used
60The gamma-rays of Co is assisted according to sterilization treatment, or handles with high frequency sterilization, ultrasonic sterilization.
Claims (7)
1, a kind of active bitter gourd soft capsule is made up of capsule content 60-80% and capsule material 40-20%, it is characterized in that they are made of following component and weight proportion:
The capsule content is made up of 1 part of active bitter gourd superfine powder, special vegetable oil 0-10 part, suspending agent 0-0.5 part, antioxidant 0-0.55 part; The capsule material is made up of 100 parts in gelatin, water 80-120 part, glycerol 10-60 part, Polyethylene Glycol 0-10 part.
2, as claims 1 described active bitter gourd soft capsule, it is characterized in that the weight proportion of each component is preferably: the capsule content is formed by 1 part of active bitter gourd superfine powder, special vegetable oil 1.5-6 part, suspending agent 0.02-0.3 part, antioxidant 0.01-0.35 part;
The capsule material by 100 parts in gelatin, water 85-110 part, glycerol 35-55 part, Polyethylene Glycol 0.025-5 part, formed.
3, as claims 1 described active bitter gourd soft capsule, it is characterized in that weight proportion the best of each component is: the capsule content is formed by 1 part of active bitter gourd superfine powder, special vegetable oil 2-4 part, suspending agent 0.025-0.2 part, antioxidant 0.03-0.25 part;
The capsule material is formed by 100 parts in gelatin, water 90-100 part, glycerol 40-50 part, Polyethylene Glycol 0.03-3 part.
4, be characterised in that as claims 1 or 2 or 3 described active bitter gourd soft capsules: described active bitter gourd superfine powder is that fresh Fructus Momordicae charantiae is through preliminary defibrination, drop into fine grinding in colloid mill or other slurry milling apparatus again, with fine grinding slurry with vacuum dehydrating at lower temperature gained powder, again through the low temperature supersonic airstream pulverize collect 600-2500 order superfine powder.
5, be characterised in that as claims 1 or 2 or 3 described active bitter gourd soft capsules: described special vegetable oil is: the superfine product Camellia oil (Extra Virgin camellia Oil) of the Extra Virgin of European Union's standard (Extra Virgin olive Oil), GB one-level.
6, be characterised in that as claims 1 or 2 or 3 described active bitter gourd soft capsules: described suspending agent is Polyethylene Glycol, lecithin, Cera Flava.
7, be characterised in that as claims 1 or 2 or 3 described active bitter gourd soft capsules: described antioxidant is tea polyphenols, apple polyphenol, Herba Rosmarini Officinalis extract, phytic acid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510079756 CN1887306A (en) | 2005-06-28 | 2005-06-28 | Active bitter gourd soft capsule and its prepn |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510079756 CN1887306A (en) | 2005-06-28 | 2005-06-28 | Active bitter gourd soft capsule and its prepn |
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| Publication Number | Publication Date |
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| CN1887306A true CN1887306A (en) | 2007-01-03 |
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| CN 200510079756 Pending CN1887306A (en) | 2005-06-28 | 2005-06-28 | Active bitter gourd soft capsule and its prepn |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101816657A (en) * | 2010-04-14 | 2010-09-01 | 湖州老恒和酿造有限公司 | Process for preparing vinegar powder soft capsules |
| CN103431372A (en) * | 2013-05-22 | 2013-12-11 | 安徽省农业科学院园艺研究所 | Preparation process for trichosanthes kirilowii seed oil unsaturated fatty acid microcapsule |
| CN105831318A (en) * | 2016-04-14 | 2016-08-10 | 朱从恩 | Polypeptide tea for blood glucose reduction and manufacturing method of polypeptide tea |
-
2005
- 2005-06-28 CN CN 200510079756 patent/CN1887306A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101816657A (en) * | 2010-04-14 | 2010-09-01 | 湖州老恒和酿造有限公司 | Process for preparing vinegar powder soft capsules |
| CN103431372A (en) * | 2013-05-22 | 2013-12-11 | 安徽省农业科学院园艺研究所 | Preparation process for trichosanthes kirilowii seed oil unsaturated fatty acid microcapsule |
| CN105831318A (en) * | 2016-04-14 | 2016-08-10 | 朱从恩 | Polypeptide tea for blood glucose reduction and manufacturing method of polypeptide tea |
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