CN109996553A - 用于在内窥镜剥离术后预防食管狭窄的自组装肽基质 - Google Patents

用于在内窥镜剥离术后预防食管狭窄的自组装肽基质 Download PDF

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Publication number
CN109996553A
CN109996553A CN201780052885.1A CN201780052885A CN109996553A CN 109996553 A CN109996553 A CN 109996553A CN 201780052885 A CN201780052885 A CN 201780052885A CN 109996553 A CN109996553 A CN 109996553A
Authority
CN
China
Prior art keywords
solution
peptide
oesophagus
self
target region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201780052885.1A
Other languages
English (en)
Chinese (zh)
Inventor
吉恩锡
玛丽·雷韦勒-布菲耶
弗里德里克·普拉特
马克西米利安·路易斯·弗朗西斯·本杰明·巴雷特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Paris Public Trust Fund (ap-Hp)
3D Matrix Ltd
Original Assignee
Paris Public Trust Fund (ap-Hp)
3D Matrix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Paris Public Trust Fund (ap-Hp), 3D Matrix Ltd filed Critical Paris Public Trust Fund (ap-Hp)
Publication of CN109996553A publication Critical patent/CN109996553A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/267—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the respiratory tract, e.g. laryngoscopes, bronchoscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A61K38/1866—Vascular endothelial growth factor [VEGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Vascular Medicine (AREA)
  • Zoology (AREA)
  • Otolaryngology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201780052885.1A 2016-06-27 2017-06-27 用于在内窥镜剥离术后预防食管狭窄的自组装肽基质 Pending CN109996553A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662355111P 2016-06-27 2016-06-27
US62/355,111 2016-06-27
PCT/US2017/039407 WO2018005427A1 (en) 2016-06-27 2017-06-27 Self-assembling peptide matrix for the prevention of esophageal stricture after endoscopic dissection

Publications (1)

Publication Number Publication Date
CN109996553A true CN109996553A (zh) 2019-07-09

Family

ID=59295359

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780052885.1A Pending CN109996553A (zh) 2016-06-27 2017-06-27 用于在内窥镜剥离术后预防食管狭窄的自组装肽基质

Country Status (8)

Country Link
US (1) US20190358290A1 (enExample)
EP (1) EP3474880A1 (enExample)
JP (2) JP2019518569A (enExample)
CN (1) CN109996553A (enExample)
AU (1) AU2017289150A1 (enExample)
BR (1) BR112018077219A2 (enExample)
CA (1) CA3029455A1 (enExample)
WO (1) WO2018005427A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2966711T3 (es) 2018-06-21 2024-04-23 Univ Pittsburgh Commonwealth Sys Higher Education Hidrogel de matriz extracelular (ECM) como almohadilla líquida submucosa
US20210244855A1 (en) * 2018-06-21 2021-08-12 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Use of an extracellular matrix (ecm) hydrogel as an esophageal submucosal fluid cushion
US11534528B2 (en) 2020-03-31 2022-12-27 3-D Matrix, Ltd. Sterilization of self-assembling peptides by irradiation
RU2751285C1 (ru) * 2020-07-22 2021-07-12 Федеральное государственное бюджетное научное учреждение "Российский научный центр хирургии имени академика Б.В. Петровского" Способ хирургического лечения стриктур пищеводных анастомозов

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015138514A1 (en) * 2014-03-10 2015-09-17 3-D Matrix, Ltd. Self-assembling peptide compositions
US20160000966A1 (en) * 2013-03-14 2016-01-07 3-D Matrix, Ltd. Materials for gastrointestinal obstruction prevention

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050245788A1 (en) * 2004-04-28 2005-11-03 Medtronic, Inc. Esophageal delivery system and method with position indexing
US9162005B2 (en) * 2005-04-25 2015-10-20 Arch Biosurgery, Inc. Compositions for prevention of adhesions and other barrier applications
JP5263756B2 (ja) * 2005-09-30 2013-08-14 国立大学法人 岡山大学 細胞の培養方法および細胞培養物
US20150105336A1 (en) * 2012-03-09 2015-04-16 3-D Matrix, Ltd. Mucosa-elevating agent

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160000966A1 (en) * 2013-03-14 2016-01-07 3-D Matrix, Ltd. Materials for gastrointestinal obstruction prevention
CN105339020A (zh) * 2013-03-14 2016-02-17 立美基股份有限公司 预防胃肠梗阻的材料
WO2015138514A1 (en) * 2014-03-10 2015-09-17 3-D Matrix, Ltd. Self-assembling peptide compositions

Also Published As

Publication number Publication date
BR112018077219A2 (pt) 2019-04-09
CA3029455A1 (en) 2018-01-04
US20190358290A1 (en) 2019-11-28
WO2018005427A1 (en) 2018-01-04
JP2019518569A (ja) 2019-07-04
JP2022023249A (ja) 2022-02-07
AU2017289150A1 (en) 2019-01-24
EP3474880A1 (en) 2019-05-01

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Application publication date: 20190709