CA3029455A1 - Self-assembling peptide matrix for the prevention of esophageal stricture after endoscopic dissection - Google Patents

Self-assembling peptide matrix for the prevention of esophageal stricture after endoscopic dissection Download PDF

Info

Publication number
CA3029455A1
CA3029455A1 CA3029455A CA3029455A CA3029455A1 CA 3029455 A1 CA3029455 A1 CA 3029455A1 CA 3029455 A CA3029455 A CA 3029455A CA 3029455 A CA3029455 A CA 3029455A CA 3029455 A1 CA3029455 A1 CA 3029455A1
Authority
CA
Canada
Prior art keywords
solution
peptide
target area
esophagus
self
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA3029455A
Other languages
English (en)
French (fr)
Inventor
Eun Seok GIL
Marie REVEILLER-BUFFIER
Frederic Prat
Maximilien Louis Francois Benjamin Barret
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Assistance Publique - Hôpitaux de Paris
3D Matrix Ltd
Original Assignee
Assistance Publique - Hôpitaux de Paris
3D Matrix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Assistance Publique - Hôpitaux de Paris, 3D Matrix Ltd filed Critical Assistance Publique - Hôpitaux de Paris
Publication of CA3029455A1 publication Critical patent/CA3029455A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/267—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the respiratory tract, e.g. laryngoscopes or bronchoscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A61K38/1866—Vascular endothelial growth factor [VEGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Vascular Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Otolaryngology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA3029455A 2016-06-27 2017-06-27 Self-assembling peptide matrix for the prevention of esophageal stricture after endoscopic dissection Abandoned CA3029455A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662355111P 2016-06-27 2016-06-27
US62/355,111 2016-06-27
PCT/US2017/039407 WO2018005427A1 (en) 2016-06-27 2017-06-27 Self-assembling peptide matrix for the prevention of esophageal stricture after endoscopic dissection

Publications (1)

Publication Number Publication Date
CA3029455A1 true CA3029455A1 (en) 2018-01-04

Family

ID=59295359

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3029455A Abandoned CA3029455A1 (en) 2016-06-27 2017-06-27 Self-assembling peptide matrix for the prevention of esophageal stricture after endoscopic dissection

Country Status (8)

Country Link
US (1) US20190358290A1 (enExample)
EP (1) EP3474880A1 (enExample)
JP (2) JP2019518569A (enExample)
CN (1) CN109996553A (enExample)
AU (1) AU2017289150A1 (enExample)
BR (1) BR112018077219A2 (enExample)
CA (1) CA3029455A1 (enExample)
WO (1) WO2018005427A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12605489B2 (en) 2018-06-21 2026-04-21 University of Pittsburgh—of the Commonwealth System of Higher Education Use of a urinary bladder ECM hydrogel as an esophageal submucosal fluid cushion
CA3103091A1 (en) * 2018-06-21 2019-12-26 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Use of an extracellular matrix (ecm) hydrogel as an esophageal submucosal fluid cushion
US20210244396A1 (en) 2018-06-21 2021-08-12 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Extracellular matrix (ecm) hydrogel as a submucosal fluid cushion
CN115397454A (zh) 2020-03-31 2022-11-25 立美基股份有限公司 通过辐照对自组装肽进行灭菌
RU2751285C1 (ru) * 2020-07-22 2021-07-12 Федеральное государственное бюджетное научное учреждение "Российский научный центр хирургии имени академика Б.В. Петровского" Способ хирургического лечения стриктур пищеводных анастомозов

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050245788A1 (en) * 2004-04-28 2005-11-03 Medtronic, Inc. Esophageal delivery system and method with position indexing
US9162005B2 (en) * 2005-04-25 2015-10-20 Arch Biosurgery, Inc. Compositions for prevention of adhesions and other barrier applications
JP5263756B2 (ja) * 2005-09-30 2013-08-14 国立大学法人 岡山大学 細胞の培養方法および細胞培養物
US20150105336A1 (en) * 2012-03-09 2015-04-16 3-D Matrix, Ltd. Mucosa-elevating agent
CA2905182A1 (en) * 2013-03-14 2014-09-18 3-D Matrix, Ltd. Materials for gastrointestinal obstruction prevention
DK3116896T3 (en) * 2014-03-10 2019-03-18 3 D Matrix Ltd SELF-PREPARING PEPTIME COMPOSITIONS

Also Published As

Publication number Publication date
AU2017289150A1 (en) 2019-01-24
CN109996553A (zh) 2019-07-09
JP2019518569A (ja) 2019-07-04
BR112018077219A2 (pt) 2019-04-09
EP3474880A1 (en) 2019-05-01
WO2018005427A1 (en) 2018-01-04
JP2022023249A (ja) 2022-02-07
US20190358290A1 (en) 2019-11-28

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20221229