CN109984977A - A kind of Essence of the glycogen containing plant and preparation method thereof - Google Patents
A kind of Essence of the glycogen containing plant and preparation method thereof Download PDFInfo
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- CN109984977A CN109984977A CN201910424185.1A CN201910424185A CN109984977A CN 109984977 A CN109984977 A CN 109984977A CN 201910424185 A CN201910424185 A CN 201910424185A CN 109984977 A CN109984977 A CN 109984977A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
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Abstract
The invention proposes Essences of a kind of glycogen containing plant and preparation method thereof, the Essence includes following component (the percentage w/w with Essence weight): carbomer 0.13%-0.17%, trehalose 0.45%-0.55%, erythrose 0.45%-0.55%, niacinamide 1.5%-2.8%, glycogen 0.28%-0.35%, parahydroxyacet-ophenone 0.3%-1.5%, carboxymethyl chitosan 0.05%-0.12%, Sodium Hyaluronate 1.5%-2.8%, leaf acyl fermentation soybean extract 0.42%-1.57%, and surplus is water.Essence of the invention can penetrate to the skin deep layer, increase skin water content and compact degree.Cell can be made to rejuvenate, reduce senile plaque, improve the colour of skin.
Description
Technical field
The present invention relates to technical field of skin care, particularly relate to a kind of Essence and preparation method thereof of glycogen containing plant.
Background technique
Topical application glycogen can provide the benefit of conditioning and aquation to skin, improve the overall appearance and quality of skin.
The research of Mirexus company also indicates that the human dermal fibroblasts of growth in vitro have higher thin in the presence of glycogen
Intracellular growth speed, produce more hyaluronic acids (HA) collagen-healthy cell characteristic and many anti-ageing benefits
Basis.
Glycogen is a kind of high branched polysaccharides with unique texture, is answered extensively because of its performance of keeping humidity and filming performance
With as the significant energy source of Skin Cell, it helps to restore skin vitality, improves smoothness, while substantially reducing old
Year spot improves the colour of skin, while increasing the compact degree and moisture content of skin, generates significant effect to skin is improved.It can be with
Increase the generation of ceramide by stimulation horn cell, improves the barrier function of moisture of skin and skin, it can also promote
The regeneration of hyaluronic acid and elastin laminin cell in epidermal cell.When you smear on the skin, can generate obvious smooth
Feeling.It can be effectively protected environment from the infringement and pollution of multiple harmful substances, while also can effectively prevent due to certainly
The water loss as caused by base activity and ultraviolet light and damage.But ultraviolet light irradiation can induce the increasing of glycogen content in epidermis
Add, the increase of cell glycogen content is reaction one of of the epidermal cell to damage, and glycogen is considered to provide and is able to satisfy quickly
Energy necessary to the demand of growth is commonly due to the epidermal cell being disturbed.Glycogen is present in embryo's epithelial cell, and
Occur again in the case where epidermal inflammation or paraplasm, these situations are caused by being exposed to ultraviolet light, incised wound or scratch
's.
In view of this, it is necessary for researching and developing the Essence of glycogen containing plant a kind of as skin care item.
Summary of the invention
The present invention proposes a kind of Essence of glycogen containing plant, which can penetrate to the skin deep layer, increases skin
Compact degree and water content.
The present invention also proposes a kind of preparation method of the Essence of glycogen containing plant, and the preparation method is simple, operation is easy,
Stability is high, is convenient for large-scale production.
The technical scheme of the present invention is realized as follows:
A kind of Essence of the glycogen containing plant, including following component (the percentage w/w with Essence weight):
Carbomer 0.13%-0.17%, trehalose 0.45%-0.55%, erythrose 0.45%-0.55%, niacinamide
1.5%-2.8%, glycogen 0.28%-0.35%, parahydroxyacet-ophenone 0.3%-1.5%, carboxymethyl chitosan 0.05%-
0.12%, Sodium Hyaluronate 1.5%-2.8%, leaf acyl fermentation soybean extract 0.42%-1.57%, surplus is water.
It as a preferred technical solution, further include the smart ammonia for accounting for Essence weight 0.10%-0.2% in the Essence
Acid；Account for the biological carbohydrate gum -1 of Essence weight 1.8%-2.2%；And account for Essence weight 0.6%-1.2% magnolol and
Magnolol.
It as a preferred technical solution, further include the EDTA for accounting for Essence weight 0.01%-0.03% in the Essence
Disodium；Account for the methyl propanediol of Essence weight 2.7%-3.5%；And account for the glycerol of Essence weight 2%-6%.
It further include as a preferred technical solution, preservative and essence in the Essence.
The Essence includes following component (the percentage w/w with Essence weight) as a preferred technical solution: card
Wave nurse 0.15, trehalose 0.5%, erythrose 0.5%, niacinamide 2%, glycogen 0.3%, parahydroxyacet-ophenone 0.4%, carboxymethyl
Chitin 0.1%, Sodium Hyaluronate 2%, leaf acyl fermentation soybean extract 0.5%, surplus is water.
The Essence includes following component (the percentage w/w with Essence weight) as a preferred technical solution: card
Wave nurse 0.15, trehalose 0.5%, erythrose 0.5%, niacinamide 2%, glycogen 0.3%, parahydroxyacet-ophenone 0.4%, carboxymethyl
Chitin 0.1%, Sodium Hyaluronate 2%, leaf acyl fermentation soybean extract 0.5%, arginine 0.15%, biological carbohydrate gum -1
2%, magnolol honokiol 1%, EDETATE SODIUM 0.02%, methyl propanediol 3%, glycerol 4%, surplus are water.
As a preferred technical solution, the Essence apply in the preparation of skin care item or skin care item.
A kind of preparation method of the Essence of the glycogen containing plant, comprising:
(1) by the water of said ratio, carbomer, trehalose, erythrose, EDETATE SODIUM, methyl propanediol, glycerol, nicotinoyl
Amine, glycogen, parahydroxyacet-ophenone, carboxymethyl chitosan and Sodium Hyaluronate are added to the container, and are heated to 75~80 DEG C, Bian Jiare
While being dispersed with stirring；
(2) mixture after step (1) stirring is cooled down, when temperature is down to 45~50 DEG C, arginine, biology sugar is added
Glue -1, magnolol, magnolol, preservative, leaf acyl fermentation soybean extract and essence continue stirring and dissolving, are lower than 38 to temperature
DEG C when to obtain the final product.
The scheme used that cools down is cooling circulating water as a preferred technical solution,.
Beneficial effect
(1) Essence of the invention can penetrate to the skin deep layer, increase skin water content and compact degree.It can make thin
Born of the same parents rejuvenate, and reduce senile plaque, improve the colour of skin.
(2) Essence of the invention is due to that can make cell rejuvenate, so color spot and obscure accumulation can be reduced,
It is used for a long time, the color of skin can be made to have the effect to bleach.
(3) preparation method of Essence is simple, operation is easy, and stability is high, is convenient for large-scale production.
Specific embodiment
The technical scheme in the embodiments of the invention will be clearly and completely described below, it is clear that described implementation
Example is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field is common
Technical staff's every other embodiment obtained without making creative work belongs to the model that the present invention protects
It encloses.
The skin that the glycogen of fluorescent marker can penetrate the mankind reaches depths, corresponding with skin corium, illustrates to match in emulsifiable paste
The glycogen set can survive, and can reach live skin cells and boost metabolism, and promote biology vital to healthy skin poly-
Close the interior generation of object.The confocal microscopy in the human skin cross section of the glycogen culture marked with rhodamine utilizes breast
The tissue samples of plasty donor mastectomy have studied infiltration of the glycogen to human skin of fluorescent marker.Dermatological specimens exist
Diffusion Cell is cultivated in flow process, culture solution is that 20%w/v plants fibrinolytic.These samples be allowed to in 32 DEG C of different time
Hatch in the glycogen solution of interior (when 1 hour, 2 hours, 4 hours, 6 hours, 12,24 hours).At every point of time, from skin
Take out glycogen solution.
It is characterized using penetrability of the confocal laser scanning microscope, CLSM to dermatological specimens.It is detected in all sample standard deviations
To fluorescence.Maximum intensity is detected near skin surface.In deeper local strength reduction.Still may be used at each position of skin
To observe fluorescence, until about 60-150 microns of depth, this illustrates that glycogen can penetrate into cortex, can be growing
It is absorbed with the living cells of differentiation.
Although most of glycogen storage of human body in liver and muscle, has also discovered a small amount of glycogen and is present in table
Skin.Sugared concentration measurement is that the epidermis of 0.465 μ g/mg is kept essentially constant over time, but is worked as in skin
It then will increase when epidermis is under pressure, such as: solarization or peeling, and it has also been found that more such example in psoriasic lesion
Son.Illustrate that glycogen may grow in cell and play a role in wound healing.
" leaf acyl fermentation soybean extract " in following embodiments is prepared according to following patents.Patent information are as follows:
The patent No. 2008801188773, denomination of invention extract of soybean and folic acid ferment the biopolymer and combinations thereof of generation together
Object, authorized announcement date on December 25th, 2013.
Remaining substance used in following embodiments is commercially available.
Embodiment 1
A kind of Essence of the glycogen containing plant, including following component: on the basis of 100g Essence；
Carbomer 0.15g, trehalose 0.5g, erythrose 0.5g, niacinamide 2g, glycogen 0.3g, parahydroxyacet-ophenone 0.4g,
Carboxymethyl chitosan 0.1g, Sodium Hyaluronate 2g, leaf acyl fermentation soybean extract 0.5g, arginine 0.15g, biological carbohydrate gum -1
2g, magnolol honokiol 1g, EDETATE SODIUM 0.02g, methyl propanediol 3g, glycerol 4g, preservative 0.8, essence 0.1, surplus
For water.
Above-mentioned Essence the preparation method is as follows:
(1) by water, carbomer, trehalose, erythrose, EDETATE SODIUM, methyl propanediol, glycerol, niacinamide, glycogen, right
Hydroxy acetophenone, carboxymethyl chitosan and Sodium Hyaluronate are added to the container, and are opened agitating function, are heated to 75 DEG C, Bian Jiare
While being dispersed with stirring；
(2) mixture after above-mentioned stirring is cooled down, when temperature is down to 45 DEG C, arginine, biological carbohydrate gum -1, lily magnolia is added
Alcohol, magnolol, preservative, leaf acyl fermentation soybean extract and essence continue stirring and dissolving, stop stirring when 35 DEG C of temperature,
Up to Essence.
Embodiment 2
A kind of Essence of the glycogen containing plant, including following component: on the basis of 100g Essence；
Carbomer 0.13g, trehalose 0.55g, erythrose 0.45g, niacinamide 2.8g, glycogen 0.35g, parahydroxyacet-ophenone
0.3g, carboxymethyl chitosan 0.05g, Sodium Hyaluronate 2.8g, leaf acyl fermentation soybean extract 0.42g, arginine 0.1g, biology
- 1 2.2g of carbohydrate gum, magnolol honokiol 1.2g, EDETATE SODIUM 0.01g, methyl propanediol 3.5g, glycerol 2g, surplus is water.
Above-mentioned Essence the preparation method is as follows:
(1) by water, carbomer, trehalose, erythrose, EDETATE SODIUM, methyl propanediol, glycerol, niacinamide, glycogen, right
Hydroxy acetophenone, carboxymethyl chitosan and Sodium Hyaluronate are added to the container, and are opened agitating function, are heated to 80 DEG C, Bian Jiare
While being dispersed with stirring；
(2) mixture after above-mentioned stirring is cooled down, when temperature is down to 50 DEG C, arginine, biological carbohydrate gum -1, lily magnolia is added
Alcohol, magnolol and leaf acyl fermentation soybean extract continue stirring and dissolving, stop stirring when 35 DEG C of temperature to get Essence.
Embodiment 3
A kind of Essence of the glycogen containing plant, including following component: on the basis of 100g Essence；
Carbomer 0.17g, trehalose 0.45g, erythrose 0.55g, niacinamide 1.5g, glycogen 0.28g, parahydroxyacet-ophenone
0.5g, carboxymethyl chitosan 0.12g, Sodium Hyaluronate 1.5g, leaf acyl fermentation soybean extract 0.57g, arginine 0.2g, biology
- 1 1.8g of carbohydrate gum, magnolol honokiol 0.6g, EDETATE SODIUM 0.03g, methyl propanediol 2.7g, glycerol 6g, surplus is water.
Above-mentioned Essence the preparation method is as follows:
(1) by water, carbomer, trehalose, erythrose, EDETATE SODIUM, methyl propanediol, glycerol, niacinamide, glycogen, right
Hydroxy acetophenone, carboxymethyl chitosan and Sodium Hyaluronate are added to the container, and are opened agitating function, are heated to 78 DEG C, Bian Jiare
While being dispersed with stirring；
(2) mixture after above-mentioned stirring is cooled down, when temperature is down to 46 DEG C, arginine, biological carbohydrate gum -1, lily magnolia is added
Alcohol, magnolol and leaf acyl fermentation soybean extract continue stirring and dissolving, stop stirring when 30 DEG C of temperature to get Essence.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
Claims (9)
1. a kind of Essence of glycogen containing plant, which is characterized in that including following component (the percentage w/ with Essence weight
W):
Carbomer 0.13%-0.17%, trehalose 0.45%-0.55%, erythrose 0.45%-0.55%, niacinamide 1.5%-
2.8%, glycogen 0.28%-0.35%, parahydroxyacet-ophenone 0.3%-1.5%, carboxymethyl chitosan 0.05%-0.12%, thoroughly
Bright matter acid sodium 1.5%-2.8%, leaf acyl fermentation soybean extract 0.42%-1.57%, surplus is water.
2. a kind of Essence of glycogen containing plant according to claim 1, which is characterized in that further include in the Essence
Account for the arginine of Essence weight 0.10%-0.2%；Account for the biological carbohydrate gum -1 of Essence weight 1.8%-2.2%；Account for Essence
The magnolol honokiol of weight 0.6%-1.2%.
3. a kind of Essence of glycogen containing plant according to claim 1, which is characterized in that further include in the Essence
Account for the EDETATE SODIUM of Essence weight 0.01%-0.03%；Account for the methyl propanediol of Essence weight 2.7%-3.5%；Account for essence
The glycerol of magnificent liquid weight 2%-6%.
4. a kind of Essence of glycogen containing plant according to claim 2 or 3, which is characterized in that in the Essence also
Including preservative and essence.
5. a kind of Essence of glycogen containing plant according to claim 1, which is characterized in that the Essence includes as follows
Component (the percentage w/w with Essence weight): carbomer 0.15, trehalose 0.5%, erythrose 0.5%, niacinamide 2%, sugar
Former 0.3%, parahydroxyacet-ophenone 0.4%, carboxymethyl chitosan 0.1%, Sodium Hyaluronate 2%, leaf acyl fermentation soybean extract
0.5%, surplus is water.
6. a kind of Essence of glycogen containing plant according to claim 1, which is characterized in that the Essence includes as follows
Component (the percentage w/w with Essence weight): carbomer 0.15, trehalose 0.5%, erythrose 0.5%, niacinamide 2%, sugar
Former 0.3%, parahydroxyacet-ophenone 0.4%, carboxymethyl chitosan 0.1%, Sodium Hyaluronate 2%, leaf acyl fermentation soybean extract
0.5%, arginine 0.15%, biological carbohydrate gum -1 2%, magnolol honokiol 1%, EDETATE SODIUM 0.02%, methyl propanediol
3%, glycerol 4%, surplus are water.
7. a kind of Essence of glycogen containing plant according to any claim from 1 to 6, which is characterized in that described
Essence apply in the preparation of skin care item or skin care item.
8. a kind of preparation method of the Essence of glycogen containing plant characterized by comprising
(1) by the water of said ratio, carbomer, trehalose, erythrose, EDETATE SODIUM, methyl propanediol, glycerol, niacinamide, sugar
Original, parahydroxyacet-ophenone, carboxymethyl chitosan and Sodium Hyaluronate are added to the container, and are heated to 75~80 DEG C, Bian Jiare is stirred on side
Mix dispersion:
(2) mixture after step (1) stirring is cooled down, when temperature is down to 45~50 DEG C, be added arginine, biological carbohydrate gum -1,
Magnolol, magnolol, preservative, leaf acyl fermentation soybean extract and essence continue stirring and dissolving, when temperature is lower than 38 DEG C
?.
9. a kind of preparation method of the Essence of glycogen containing plant according to claim 8, which is characterized in that the cooling
The scheme used is cooling circulating water.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110711163A (en) * | 2019-11-27 | 2020-01-21 | 珠海伊斯佳科技股份有限公司 | Instant firming essence and preparation method and application thereof |
| CN111991306A (en) * | 2020-09-29 | 2020-11-27 | 珠海远大美业生物科技有限公司 | Anti-aging repairing pure liquid, preparation method and application thereof |
| CN112972295A (en) * | 2021-04-12 | 2021-06-18 | 东晟源研究院(广州)有限公司 | Oil-controlling and acne-inhibiting rosewood seed essence |
| CN114917143A (en) * | 2022-05-19 | 2022-08-19 | 大连大学 | Skin aging resistant sea cucumber polypeptide repair essence and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110711163A (en) * | 2019-11-27 | 2020-01-21 | 珠海伊斯佳科技股份有限公司 | Instant firming essence and preparation method and application thereof |
| CN111991306A (en) * | 2020-09-29 | 2020-11-27 | 珠海远大美业生物科技有限公司 | Anti-aging repairing pure liquid, preparation method and application thereof |
| CN112972295A (en) * | 2021-04-12 | 2021-06-18 | 东晟源研究院(广州)有限公司 | Oil-controlling and acne-inhibiting rosewood seed essence |
| CN114917143A (en) * | 2022-05-19 | 2022-08-19 | 大连大学 | Skin aging resistant sea cucumber polypeptide repair essence and preparation method thereof |
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