CN109959690B - 一种用于电化学识别色氨酸对映体的环己烷二甲酸衍生物修饰电极的制备方法 - Google Patents
一种用于电化学识别色氨酸对映体的环己烷二甲酸衍生物修饰电极的制备方法 Download PDFInfo
- Publication number
- CN109959690B CN109959690B CN201910291488.0A CN201910291488A CN109959690B CN 109959690 B CN109959690 B CN 109959690B CN 201910291488 A CN201910291488 A CN 201910291488A CN 109959690 B CN109959690 B CN 109959690B
- Authority
- CN
- China
- Prior art keywords
- cyclohexanedicarboxylic acid
- acid derivative
- electrode
- modified electrode
- tryptophan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- QYQADNCHXSEGJT-UHFFFAOYSA-N cyclohexane-1,1-dicarboxylate;hydron Chemical class OC(=O)C1(C(O)=O)CCCCC1 QYQADNCHXSEGJT-UHFFFAOYSA-N 0.000 title claims abstract description 49
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical class C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 title claims abstract description 26
- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- 238000000034 method Methods 0.000 claims abstract description 8
- 238000002848 electrochemical method Methods 0.000 claims abstract description 4
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims description 15
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 claims description 10
- 239000000243 solution Substances 0.000 claims description 10
- 229930182827 D-tryptophan Natural products 0.000 claims description 7
- QIVBCDIJIAJPQS-SECBINFHSA-N D-tryptophane Chemical compound C1=CC=C2C(C[C@@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-SECBINFHSA-N 0.000 claims description 7
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims description 6
- QOSSAOTZNIDXMA-UHFFFAOYSA-N Dicylcohexylcarbodiimide Chemical compound C1CCCCC1N=C=NC1CCCCC1 QOSSAOTZNIDXMA-UHFFFAOYSA-N 0.000 claims description 5
- 238000002484 cyclic voltammetry Methods 0.000 claims description 5
- JRBPAEWTRLWTQC-UHFFFAOYSA-N dodecylamine Chemical compound CCCCCCCCCCCCN JRBPAEWTRLWTQC-UHFFFAOYSA-N 0.000 claims description 5
- 230000000694 effects Effects 0.000 claims description 5
- 239000008055 phosphate buffer solution Substances 0.000 claims description 5
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 claims description 5
- 238000005406 washing Methods 0.000 claims description 5
- 229910021397 glassy carbon Inorganic materials 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 3
- ZOMNIUBKTOKEHS-UHFFFAOYSA-L dimercury dichloride Chemical class Cl[Hg][Hg]Cl ZOMNIUBKTOKEHS-UHFFFAOYSA-L 0.000 claims description 3
- 229910052697 platinum Inorganic materials 0.000 claims description 3
- 238000002390 rotary evaporation Methods 0.000 claims description 3
- 239000002904 solvent Substances 0.000 claims description 3
- 238000010408 sweeping Methods 0.000 claims description 3
- 238000001291 vacuum drying Methods 0.000 claims description 3
- 238000005259 measurement Methods 0.000 claims 1
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 230000003647 oxidation Effects 0.000 description 4
- 238000007254 oxidation reaction Methods 0.000 description 4
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 125000000524 functional group Chemical group 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 239000003960 organic solvent Substances 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 229960004799 tryptophan Drugs 0.000 description 2
- 230000009471 action Effects 0.000 description 1
- -1 amino acid enantiomers Chemical class 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000005557 chiral recognition Methods 0.000 description 1
- 238000001318 differential pulse voltammogram Methods 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 239000003349 gelling agent Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000000655 nuclear magnetic resonance spectrum Methods 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000759 toxicological effect Toxicity 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/308—Electrodes, e.g. test electrodes; Half-cells at least partially made of carbon
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
- G01N27/3277—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a redox reaction, e.g. detection by cyclic voltammetry
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
Abstract
Description
Claims (4)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910291488.0A CN109959690B (zh) | 2019-04-12 | 2019-04-12 | 一种用于电化学识别色氨酸对映体的环己烷二甲酸衍生物修饰电极的制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910291488.0A CN109959690B (zh) | 2019-04-12 | 2019-04-12 | 一种用于电化学识别色氨酸对映体的环己烷二甲酸衍生物修饰电极的制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN109959690A CN109959690A (zh) | 2019-07-02 |
CN109959690B true CN109959690B (zh) | 2021-03-16 |
Family
ID=67026053
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201910291488.0A Active CN109959690B (zh) | 2019-04-12 | 2019-04-12 | 一种用于电化学识别色氨酸对映体的环己烷二甲酸衍生物修饰电极的制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN109959690B (zh) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105758915B (zh) * | 2016-03-02 | 2018-01-02 | 常州大学 | 一种羧甲基纤维素‑壳聚糖复合材料的制备及其修饰电极电化学法识别色氨酸对映体 |
CN108017725B (zh) * | 2018-01-18 | 2020-05-12 | 西北师范大学 | 多壁碳纳米管-n-羧甲基壳聚糖手性材料的制备及应用 |
CN108490048A (zh) * | 2018-03-16 | 2018-09-04 | 常州大学 | 一种用于电化学识别氨基酸对映体的ctab自组装杯芳烃的手性传感器的制备方法 |
CN108918621A (zh) * | 2018-05-16 | 2018-11-30 | 常州大学 | 一种用于电化学识别色氨酸对映体的ctab自组装杯芳烃衍生物的手性传感器的制备方法 |
CN108645902A (zh) * | 2018-05-16 | 2018-10-12 | 常州大学 | 一种用于电化学法识别色氨酸对映体的手性杯芳烃衍生物修饰电极的制备方法 |
-
2019
- 2019-04-12 CN CN201910291488.0A patent/CN109959690B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
CN109959690A (zh) | 2019-07-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN106226370B (zh) | 一种草甘膦分子印迹电化学传感器的制备方法 | |
CN104297316B (zh) | 一种基于β-环糊精的手性传感器及其制备方法 | |
CN104792844A (zh) | 一种壳聚糖-碳量子点复合膜修饰电极的制备及其应用于电化学识别色氨酸对映体 | |
CN105044173B (zh) | 一种石墨烯量子点/β‑环糊精复合膜修饰电极的制备及其应用于电化学法识别色氨酸对映体 | |
CN107490611B (zh) | 一种手性mof-聚苯胺杂化材料及其制备方法和应用 | |
CN105223248A (zh) | 基于苯硼酸印迹聚合物/碳纳米管修饰电极及其制备方法和应用 | |
CN105044178A (zh) | 基于壳聚糖/海藻酸钠的手性传感器对含有锌离子的色氨酸对映体的手性识别 | |
CN106841354A (zh) | 基于壳聚糖/α‑环糊精双核铜自组装手性传感器的制备与应用 | |
CN108645902A (zh) | 一种用于电化学法识别色氨酸对映体的手性杯芳烃衍生物修饰电极的制备方法 | |
CN109959690B (zh) | 一种用于电化学识别色氨酸对映体的环己烷二甲酸衍生物修饰电极的制备方法 | |
CN109975379A (zh) | 一种用于电化学识别色氨酸对映体的壳聚糖/脱氧核糖核酸修饰电极的制备方法 | |
CN104655708B (zh) | 聚对氨基苯磺酸/印迹聚邻苯二胺修饰电极及其制备方法和应用 | |
CN111257388B (zh) | 一种利用手性超分子凝胶修饰电极电化学识别色氨酸对映体的方法 | |
CN109752433A (zh) | 一种磷酸镍/Co-MOFs复合材料及其制备方法和应用 | |
CN103399063A (zh) | 一种基于植酸分散的石墨烯纳米材料修饰的玻碳电极及其制备方法和应用 | |
Brinić et al. | Bismuth film random array carbon fiber microelectrodes for determination of cysteine and N-acetyl cysteine | |
CN107219277B (zh) | 分子印迹过氧化聚吡咯/聚对氨基苯磺酸修饰电极的制备 | |
CN106645359A (zh) | 用电化学传感分析技术测定ⅱ型拟除虫菊酯农药残留的方法 | |
CN108562628B (zh) | 一种可应用于电化学手性识别的α-环糊精包结谷胱甘肽复合材料修饰电极的制备 | |
CN108841034A (zh) | 一种可用于电化学识别色氨酸对映体的分子印迹二氧化硅/海藻酸钠复合材料的制备方法 | |
CN114045540B (zh) | 碳纳米管/芘四羧酸/壳聚糖手性材料、制备方法及应用 | |
CN109828011A (zh) | 一种铁基有机骨架材料MIL-100(Fe)及其电化学制备方法与应用 | |
CN110330579B (zh) | 一种应用于电化学手性识别的β-环糊精类索烃分子的制备方法 | |
CN113567516A (zh) | 一种磺胺间甲氧嘧啶分子印迹电极及其制备方法、应用 | |
CN108918621A (zh) | 一种用于电化学识别色氨酸对映体的ctab自组装杯芳烃衍生物的手性传感器的制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20190702 Assignee: Shandong Hongde Yuheng Information Technology Co.,Ltd. Assignor: CHANGZHOU University Contract record no.: X2024980008518 Denomination of invention: Preparation method of cyclohexane dicarboxylic acid derivative modified electrode for electrochemical recognition of tryptophan enantiomers Granted publication date: 20210316 License type: Common License Record date: 20240702 |